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Independently Validated Sex-Specific Nomograms For Predicting Survival In Patients With Newly Diagnosed Glioblastoma: Nrg Oncology Rtog 0525 And 0825, Minesh Mehta

All Publications

No abstract provided.

Consensus Guidelines For The Definition Of Time-To-Event End Points In Image-Guided Tumor Ablation: Results Of The Sio And Datecan Initiative, Govindarajan Narayanan

All Publications

There is currently no consensus regarding preferred clinical outcome measures following image-guided tumor ablation or clear definitions of oncologic end points. This consensus document proposes standardized definitions for a broad range of oncologic outcome measures with recommendations on how to uniformly document, analyze, and report outcomes. The initiative was coordinated by the Society of Interventional Oncology in collaboration with the Definition for the Assessment of Time-to-Event End Points in Cancer Trials, or DATECAN, group. According to predefined criteria, based on experience with clinical trials, an international panel of 62 experts convened. Recommendations were developed using the validated three-step modified Delphi …

Developing Risk Assessment Tool For Patients’ In-Hospital Falls Using Predictive Modeling, Rasika Patil

Theses

Inpatient falls are a serious cause of fatal and non-fatal injuries among patients of all ages leading to disability and stillness. The post-fall treatment comes with rising medical costs and a stressful recovery phase. The present assessment tools align with analyzing causes of falls from historical data instead of present conditions. The key focus area of this research is to develop general-purpose fall risk assessment tools using machine learning-based predictive modeling. We used performance metrics to compare the accuracy and suggest the best suitable model for each shift. This general-purpose fall risk assessment tool can be used for all age …

Quantum Correlations Using Classical Detectors, Chamithri Adikarige

Theses

Single photons are vital to quantum computing, information processing, and transportation. Popular single-photon experiments are one or two-photon interference, classification of the light source, and characterization of detectors. Currently, the most efficient detector in the telecom wavelength is the Superconducting Nanowire detector. How- ever, experiments have been successful in demonstrating single-photon measurements can be done with unconventional detectors. One such method employed an EMCCD camera to observe spatial correlations between pixels with single photons. This thesis aims to test non-single photon-counting PIN photodetectors to observe time-correlation measurement. The improved detection model uses a high-resolution 2GHz oscilloscope and a cross-correlation algorithm. …

Medicaid To Schools Technical Assistance Guide, Lucy Hodder, Kelsi West, Victoria Forkus, Department Of Health And Human Services (Dhhs), Medicaid To Schools (Mts) Team

All Materials

Purpose: The purpose of this Medicaid to Schools (MTS) Technical Assistance Guide is to memorialize in one document the formal existing rules and guidance approved by New Hampshire Department of Health and Human Services for the Medicaid to Schools program. The administrative rules (He-W) and formal guidance in the form of “Information Bulletins” is referenced and categorized by topic. The user can link internally to sections for clarification and can link to external sources for clarification.

Scope: This Technical Assistance Guide includes only those resources that have been formally adopted by DHHS.

Contents: Each section of this Technical Assistance Guide …

Closing The Contextual And Chronological Gap: A Design And Development Study Of A Systematic Tool For The Selection Of Learning And Performance Support Interventions, James Knapp Iii

STEMPS Theses & Dissertations

Gaps in human performance resulting from a lack of skills and knowledge require solutions – interventions. The process of selecting the most effective intervention (solution) for closing a skills and knowledge gap—such as classroom training, e-Learning, Structured on-the-job Training (SOJT), or job-aid—is a fundamental and vital practice for Human Performance Technology (HPT) practitioners. Unlike other activities in the Performance Improvement/HPT (PI/HPT) model, the activity of intervention selection is ambiguous. Meaning, there is currently no systematic process or tool in place for selecting learning and performance-improvement solutions that is reflective of the learning science. Consequently, the critical activity of intervention selection …

Shipboard Lidar As A Tool For Remotely Measuring The Distribution And Bulk Characteristics Of Marine Particles, Brian Leigh Collister

OES Theses and Dissertations

Light detection and ranging (lidar) can provide remote estimates of the vertical distribution of optical properties in the ocean, potentially revolutionizing our ability to characterize the spatial structure of upper ocean ecosystems. However, challenges associated with quantifying the relationship between lidar measurements and biogeochemical properties of interest have prevented its adoption for routinely mapping the vertical structure of marine ecosystems. To address this, we developed a shipboard oceanographic lidar that measures attenuation (α) and linear depolarization (δ) at scales identical to those of in-water optical and biogeochemical measurements. The instrument’s ability to resolve the distribution of optical and biogeochemical properties …

A Copula Model Approach To Identify The Differential Gene Expression, Prasansha Liyanaarachchi

Mathematics & Statistics Theses & Dissertations

Deoxyribonucleic acid, more commonly known as DNA, is a complex double helix-shaped molecule present in all living organisms and hosts thousands of genes. However, only a few genes exhibit differential expression and play a vital role in a particular disease such as breast cancer. Microarray technology is one of the modern technologies developed to study these gene expressions. There are two major microarray technologies available for expression analysis: Spotted cDNA array and oligonucleotide array. The focus of our research is the statistical analysis of data that arises from the spotted cDNA microarray. Numerous models have been proposed in the literature …

Synthesis And Characterization Of 4,6-Protected Glucosamine Derivatives And Branched Glycoconjugates, Jonathan Bietsch

Chemistry & Biochemistry Theses & Dissertations

Low molecular weight gelators (LMWGs) are small molecules that self-assemble in appropriate solvents to form three dimensional networks that immobilize the solvent, creating a supramolecular gel. The self-assembly of LMWGs occurs through non-covalent interactions such as hydrogen bonding, aromatic interactions, donor-acceptor interactions, Van der Waals interactions, hydrophobic forces, halogen bonding, etc. Due to self-assembly occurring through reversible non-covalent interactions, supramolecular gels can undergo a gel to solution transformation. Because of this, these materials can be sensitive to external stimuli such as temperature changes, pH changes, and other stimuli that effect non-covalent interactions. This makes the synthesis of LMWG’s an appealing …

The Cross-Sectional Association Of Cognition With Diabetic Peripheral And Autonomic Neuropathy–The Grade Study, Joshua I Barzilay, Alokananda Ghosh, Rodica Pop Busui, Andrew Ahmann, Ashok Balasubramanyam, Mary Ann Banerji, Robert M Cohen, Jennifer Green, Faramarz Ismail-Beigi, Catherine L Martin, Elizabeth Seaquist, José A Luchsinger, Grade Research Group

Faculty, Staff and Students Publications

BACKGROUND: Studies examining whether measures of cognition are related to the presence of diabetic peripheral neuropathy (DPN) and/or cardiovascular autonomic neuropathy (CAN) are lacking, as are data regarding factors potentially explaining such associations.

METHODS: Participants were from the Glycemia Reduction Approaches in Diabetes Study (GRADE) that examined 5047 middle-aged people with type 2 diabetes of(memory) were assessed with the Spanish English Verbal Learning Test; frontal executive function and processing speed with the Digit Symbol Substitution Test; and ability to concentrate and organize data with word and animal fluency tests. DPN was assessed with the Michigan Neuropathy Screening Instrument and CAN …

Joint Linear And Nonlinear Computation With Data Encryption For Efficient Privacy-Preserving Deep Learning, Qiao Zhang

Electrical & Computer Engineering Theses & Dissertations

Deep Learning (DL) has shown unrivalled performance in many applications such as image classification, speech recognition, anomalous detection, and business analytics. While end users and enterprises own enormous data, DL talents and computing power are mostly gathered in technology giants having cloud servers. Thus, data owners, i.e., the clients, are motivated to outsource their data, along with computationally-intensive tasks, to the server in order to leverage the server’s abundant computation resources and DL talents for developing cost-effective DL solutions. However, trust is required between the server and the client to finish the computation tasks (e.g., conducting inference for the newly-input …

Securities Law: Overview And Contemporary Issues, Neal Newman, Lawrence J. Trautman

Faculty Scholarship

This is not your grandfather’s SEC anymore. Rapid technological change has resulted in novel regulatory issues and challenges, as law and policy struggles to keep pace. The U.S. Securities and Exchange Commission (SEC) reports that “the U.S. capital markets are the deepest, most dynamic, and most liquid in the world. They also have evolved to become increasingly fast and extraordinarily complex. It is our job to be responsive and innovative in the face of significant market developments and trends.” With global markets increasingly interdependent and interconnected and, “as technological advancements and commercial developments have changed how our securities markets operate, …

Fuel Load, Stand Structure, And Understory Species Composition Following Prescribed Fire In An Old-Growth Coast Redwood (Sequoia Sempervirens) Forest, David Cowman, Will Russell

Faculty Research, Scholarly, and Creative Activity

Background: With the prevalence of catastrophic wildfire increasing in response to widespread fire suppression and climate change, land managers have sought methods to increase the resiliency of landscapes to fire. The application of prescribed burning in ecosystems adapted to fire can reduce fuel load and fire potential while minimizing impacts to the ecosystem as a whole. Coast redwood forests have historically experienced fire from both natural and anthropogenic sources, and are likely to respond favorably to its reintroduction. Results: Random sampling was conducted in three burned sites and in three unburned sites, in an old-growth coast redwood (Sequoia sempervirens [D. …

Species And Population Specific Gene Expression In Blood Transcriptomes Of Marine Turtles, Shreya M. Banerjee, Jamie Adkins Stoll, Camryn D. Allen, Jennifer M. Lynch, Heather S. Harris, Lauren Kenyon, Richard E. Connon, Eleanor J. Sterling, Eugenia Naro-Maciel, Kathryn Mcfadden, Margaret M. Lamont, James Benge, Nadia B. Fernandez, Jeffrey A. Seminoff, Scott R. Benson, Rebecca L. Lewison, Tomoharu Eguchi, For Full Author List, See Comments Below

Faculty Research, Scholarly, and Creative Activity

Background: Transcriptomic data has demonstrated utility to advance the study of physiological diversity and organisms’ responses to environmental stressors. However, a lack of genomic resources and challenges associated with collecting high-quality RNA can limit its application for many wild populations. Minimally invasive blood sampling combined with de novo transcriptomic approaches has great potential to alleviate these barriers. Here, we advance these goals for marine turtles by generating high quality de novo blood transcriptome assemblies to characterize functional diversity and compare global transcriptional profiles between tissues, species, and foraging aggregations. Results: We generated high quality blood transcriptome assemblies for hawksbill (Eretmochelys …

Resources For The Homeless Youth, Cindy Garcia-Silva

Capstone Projects and Master's Theses

The internship was completed at Youth Alliance, across all of their projects. The rise in homelessness around San Benito county and its adjacent counties has caused numerous people to lose their homes. Most of these people are low income and their children have to go through losing their home, living in shelters, or seeking shelter with a family member or family friend. This project was devised and used to provide research and background information on homelessness and what it can do to youth who have to experience homelessness. The purpose for developing this binder is to help address the high …

Educating Asian American College Students On The Importance Of Community And Mentorship, Jeah Limbag

Capstone Projects and Master's Theses

Many college students may find it challenging to discover and create a supportive and consistent community or establish meaningful relationships in school. Asian American college students, in particular, have cultural values, experiences, and ideologies that can limit seeking mentors and establishing a social support network. The consequences of this could be increased feelings of loneliness and isolation, worse mental health, lower academic performance, lower attendance, and an increased likelihood of dropping out of school. To address these challenges, I have created an interactive presentation bringing awareness of the importance of mentorship and community to students in the Asian and Pacific …

Assigning Assessment Accommodations To English Learners: A Phenomenological Study, Heather May Villalobos Pavia

Dissertations

The English learner (EL) student population has grown steadily for the past 20 years. During this time, the use of standardized assessments has increased as well. Teacher understanding of assessment accommodations that best support ELs is low, despite the research that shows the unreliability of standardized achievement tests that measure the academic achievement of ELs. The purpose of this qualitative, phenomenological study was to examine how 10 teachers engage in the assessment accommodation selection process. Teachers were intentionally selected from intermediate elementary grades where the most native (primary/home) language accommodations are available on state assessments. Data were collected through surveys, …

The Relationship Between Trauma, Attachment, Self-Compassion, And Emotion Regulation: A Structural Equation Model, Susanna Jane Turner

Dissertations

Previous research has examined the relationship between trauma, attachment, selfcompassion, and emotion regulation, but never with an incarcerated population. Given the link between emotion regulation and illegal behaviors, it may be helpful to more fully understand this relationship in order to lay the groundwork for future intervention research. I gathered data from 378 participants. I then examined the relationships between these constructs on data from 204 participants, the number that remained after cleaning the data, by way of a structural equation model. Findings suggest that greater experiences of trauma may lead to insecure attachment styles, impacting individuals’ ability to trust …

An Investigation Of Outsourcing Ticket Sales In Division I College Athletics, Kyle John Brannigan

Dissertations

Understanding the phenomenon of outsourcing ticket sales in collegiate athletics can help athletic departments make more informed ticketing decisions. The purpose of this qualitative phenomenological research study was to help create new and emerging knowledge of outsourcing ticket sales in collegiate athletics from the interactions with the study’s participants. The study had 15 participants who experienced the decision-making process as well as the stakeholder impact of outsourcing ticket sales in collegiate athletics. After doing a thematic analysis of the data, eight final themes were used to help describe the phenomenon. It was clear that the importance of being able to …

Evaluation Of Recommended Modular Email Building Approaches, Palak Sadhwani

Electronic Theses, Projects, and Dissertations

Customer relationship management acts as the backbone of marketing. For any company marketing is the most important sector to promote a company and attract customers. Email marketing is one of the most effective ways of digital marketing. However, the cost of design and development is time consuming and redundant. Marketers and project managers are frequently unassertive about how to solve these issues. Although there are blogs, articles and services available for marketing email development, the lack of research in the effectiveness of email building architecture bolsters the need for this study. The project presents an architecture that modularizes the way …

Human Resource Information Systems: Implementing Data Analytics Techniques In Human Resource Functions, Prachi Tembhekar

Electronic Theses, Projects, and Dissertations

This project investigated analytical techniques used by organizations across many industries for HR functions, and how data analytical techniques can help HR departments work efficiently. The goal was to look into the obstacles and opportunities that companies have when using HR analytics as a tool in their businesses. This project used secondary data acquired from earlier research articles, journals from the years 2016 to 2019, blogs, and websites to investigate theories and applications of HR analytics. It also examined the need of analytics to assist HR leaders in thinking about the implications of these technologies in future work and how …

Enhancing The Relationship Between Students And Teachers In A Socially Distanced World By Humanizing Online Education: A Guide For Higher Education Instructors, Gilma Linette Ramirez Reyes

Electronic Theses, Projects, and Dissertations

To maintain and continue to build long-lasting professional, educational, and personal relationships, this project provides a formal academic way of teaching for instructors, but it also that reflects what the heart of teaching should be about. It shows how instructors can facilitate care and demonstrate genuine positive intentions to their students when facilitating learning in an online environment. This goes beyond the only course content materials presented and moves to an educational experience that is cultivated through the student-instructor community.

The humanizing approach to online instruction for this project is defined as the center of communication and presence which includes …

Beginning The Information Security Journey For Small And Medium Enterprises Through Business Continuity Planning And Infrastructure Automation, Aaron Chamberlain

Electronic Theses, Projects, and Dissertations

Technology has become an essential component of enterprises, driving productivity, innovation, and defining entire processes and product categories. However, these advances come with additional risk; the devices that drive an enterprise can fail at any time or be attacked by malicious actors. Larger enterprises have learned to deal with these risks, but small and medium-sized enterprises (SMEs) have been largely left behind. This project sought to investigate the cybersecurity-related problems SMEs experience and what SMEs can do to solve them. In addition, the project examines the types of information security incidents that occur within SMEs and their financial preparedness for …

Correctional Career Pathways: A Jail Reentry Program Evaluation, Grace Gass

Electronic Theses and Dissertations

There are numerous types of reentry programs available to inmates to help avoid the cycle of recidivism. There is little research on the impacts of reentry programs in jail populations. This current study sought to provide more research in this area by evaluating a local jail reentry program’s effect on recidivism. A quasi-experimental design was used to estimate the program’s effectiveness by comparing the recidivism statistics of inmates that have participated in the reentry program to a control group of inmates that did not. Inmates in the control group were matched according to their gender, age, race, and current offense …

School Accountability And Chronic Absenteeism In The State Of Tennessee, Heidi Campbell

Electronic Theses and Dissertations

The purpose of this quantitative, non-experimental study was to explore a possible relationship between the number of students in grades 9-12 classified as chronically absent and the inclusion of the Chronically Out of School indicator in Tennessee’s accountability model for schools and school districts. Using publicly available data from the Tennessee Department of Education, the research study examined 6 years of data from the 2014-2015 to 2019-2020 school years. Data were divided into 3 years before and 3 years after implementation.

Results of the study indicated that the mean number of chronically absent students in grades 9-12 were significantly lower …

Sprinkler Irrigation System Field Checklist, Charles C. Hillyer, R. Troy Peters, Xin Qiao, Derek M. Heeren, Jake Larue, Clarence Prestwich, Sandeep Bhatti

Department of Agricultural and Biological Systems Engineering: Faculty Publications

This recommendation came out of a noted need by the ASABE NRES-241 sprinkler irrigation committee in 2019 committee meeting for a simple checklist to quickly educate new center pivot operators on what to look for to determine if a center pivot is operating at designed performance. This checklist is meant to be simple and user friendly. Simple and clear language was incorporated purposefully. It is intended as a quick guide to new irrigators, or as a reminder to more experienced irrigators as to what to check to ensure efficient and effective center pivot and linear move irrigation system operation for …

Narrative Review-Drug Delivery In Age-Related Macular Degeneration, Rachel Israilevich, Raziyeh Mahmoudzadeh, Mirataollah Salabati, David Xu

Wills Eye Hospital Papers

This narrative review highlights routes of ocular drug delivery for age-related macular degeneration (AMD). AMD is the leading cause of irreversible blindness in industrialized countries and accounts for 8.7% of blindness worldwide. Advanced AMD can be classified into two subtypes: late-stage dry AMD [known as geographic atrophy (GA)] and neovascular AMD (nAMD). GA is often bilateral and results from progressive and irreversible loss of photoreceptors and areas of the retinal pigment epithelium. Wet AMD is characterized by angiogenesis from the choroid to the normally avascular regions underneath the retinal pigment epithelium (RPE) or retina, a process known as choroidal neovascularization …

Movin’ On Up? A Survey Experiment On Mobility Enhancing Policies, Jared Barton, Xiaofei Pan

Economics Faculty Journal Articles

We use a nationwide survey experiment in the United States to measure whether information on intergenerational economic mobility or policy-specific arguments influence support for six pro-mobility policies advocated by political entrepreneurs. We find the information treatments do not affect support, but the argument treatments significantly increase support for three of the policies. We also include a behavioral measure by allowing respondents the opportunity to write their U.S. Senators. We find argument treatments significantly increase the likelihood that letters address economic mobility and significantly promote advocacy for that policy in the letter, but no increase in advocacy from the information treatments. …

Research On The Impact Of Social Responsibility Of Chinese Real Estate Enterprises On Their Competitiveness, Yajiang Xing

Dissertations and Theses Collection (Open Access)

The real estate industry has become the pillar industry of China's national economy and should perform more social responsibilities. Then how to guide enterprises to perform relevant social responsibilities, how to make full use of social responsibilities to enhance enterprise competitiveness, and how to measure the aspects in which corporate social responsibility promotes the development of competitiveness have aroused the discussion and research of the government and relevant academic circles.Therefore, this paper first puts forward a series of assumptions from the perspective of stakeholders.Secondly, establish the evaluation index system of social responsibility and social competitiveness of real estate enterprises through …

Contrast-Enhanced Ultrasound Of Muscle Perfusion May Indicate Patient Response To Left Ventricular Assist Device Therapy., Lauren J. Delaney, Kathleen Fitzgerald, Maria Stanczak, Priscilla Machado, John W..C. Entwistle, Flemming Forsberg, Gordon R. Reeves

Department of Radiology Faculty Papers

PURPOSE: Left ventricular assist device (LVAD) support is associated with peripheral vascular abnormalities beyond those associated with heart failure (HF). These abnormalities are associated with persistent functional impairments that adversely impact quality of life (QoL). Methods for measuring peripheral vascular function in this population are needed.

METHODS: This pilot study investigated the use of contrast-enhanced ultrasound (CEUS) using standardized protocols to estimate changes in peripheral (quadriceps) muscle perfusion among patients with HF (INTERMACS profile 3) undergoing LVAD implantation (n = 7). Patients were then stratified by those who did ("responders", n = 4) and did not ("nonresponders", n = 3) …