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2021

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Airframe And Systems Design, Analysis, And Testing Of The Horizon Morphing-Wing Aircraft, Sabrina A. Snow Dec 2021

Airframe And Systems Design, Analysis, And Testing Of The Horizon Morphing-Wing Aircraft, Sabrina A. Snow

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Morphing trailing edge technology can provide the ability to dynamically alter the twist distribution, and therefore lift distribution, of an aircraft during flight. There are certain optimal lift distributions which can be chosen to create proverse yawing effects and eliminate the need for vertical control surfaces. The purpose of this project is to support the design and testing of a morphing, crescent flying wing airframe which will be used to evaluate yaw control in an aircraft without vertical control surfaces. There are three main objectives of this project, which are to perform static and dynamic analysis on the crescent wing …


Forecasting Stock Market Prices: A Machine Learning Approach, Abraham Alhomadi Dec 2021

Forecasting Stock Market Prices: A Machine Learning Approach, Abraham Alhomadi

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

There has been extensive literature written about the efficiency of the stock market. Practitioners and academicians have debated whether investors can exploit publicly available information to generate excess returns. Clearly predicting the stock market’s return with high accuracy has been enormously difficult, but we are interested in contributing to the continuous exploration of the efficiency of the stock market using machine learning techniques. We also want to examine the relationship between our dataset’s macroeconomic indicators and foreign nations’ stock markets with our target feature—the S&P 500. In this paper, we will be using supervised machine learning models, like Linear Regression, …


Willingness To Pay For Fact-Checking About Immigration: The Effect Of Partisan Cues, Jennifer Morales Dec 2021

Willingness To Pay For Fact-Checking About Immigration: The Effect Of Partisan Cues, Jennifer Morales

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

I analyze the results of an online experiment designed to elicit individuals’ willingness to pay for fact-checking of statements related to immigration. Using a control and treatment group, I test whether individuals’ willingness to pay is affected by partisan cues. First, I outline this research’s position related to existing literature. I then describe the experimental design and analyze the results. Partisan cues are shown to have no statistically significant effect on participants’ willingness to pay for fact-checking.


Health Reform Reconstruction, Lindsay F. Wiley, Elizabeth Mccuskey, Matthew B. Lawrence, Erin C. Fuse Brown Dec 2021

Health Reform Reconstruction, Lindsay F. Wiley, Elizabeth Mccuskey, Matthew B. Lawrence, Erin C. Fuse Brown

Faculty Scholarship

This Article connects the failed, inequitable U.S. coronavirus pandemic response to conceptual and structural constraints that have held back U.S health reform for decades and calls for reconstruction. For more than a half-century, a cramped "iron triangle" ethos has constrained health reform conceptually. Reforms aimed to balance individual interests in cost, quality, and access to health care, while marginalizing equity, solidarity, and public health. In the iron triangle era, reforms unquestioningly accommodated four legally and logistically entrenched fixtures - individualism, fiscal fragmentation, privatization, and federalism - that distort and diffuse any reach toward social justice. The profound racial disparities and …


Lung Nodules Identification In Ct Scans Using Multiple Instance Learning., Wiem Safta Dec 2021

Lung Nodules Identification In Ct Scans Using Multiple Instance Learning., Wiem Safta

Electronic Theses and Dissertations

Computer Aided Diagnosis (CAD) systems for lung nodules diagnosis aim to classify nodules into benign or malignant based on images obtained from diverse imaging modalities such as Computer Tomography (CT). Automated CAD systems are important in medical domain applications as they assist radiologists in the time-consuming and labor-intensive diagnosis process. However, most available methods require a large collection of nodules that are segmented and annotated by radiologists. This process is labor-intensive and hard to scale to very large datasets. More recently, some CAD systems that are based on deep learning have emerged. These algorithms do not require the nodules to …


Materials And Process Design For Ceramic Fused Filament Fabrication (Cf3) Of Hydroxyapatite., Kavish Sudan Dec 2021

Materials And Process Design For Ceramic Fused Filament Fabrication (Cf3) Of Hydroxyapatite., Kavish Sudan

Electronic Theses and Dissertations

Ceramic fused filament fabrication (CF3) enables the fabrication of highly customizable ceramic parts at relatively lower costs compared to other AM technologies. Advanced ceramics, having specific or niche applications, call for a high level of accuracy to meet the performance requirements. For achieving the desired level of accuracy in any manufacturing process, it is important to know the effect of involved parameters at different stages of fabrication. CF3 has been around for a while but there has been a severe lack of literature dealing with understanding the effect of process parameters on the final part properties. In this study, Hydroxyapatite …


The Economic Rationality Of Consumption In The Mycenaean Political Economy And Its Role In The Reproduction Of Social Personae: Modeling Prestige Networks., Devin Alexander Stephens Dec 2021

The Economic Rationality Of Consumption In The Mycenaean Political Economy And Its Role In The Reproduction Of Social Personae: Modeling Prestige Networks., Devin Alexander Stephens

Electronic Theses and Dissertations

This thesis is a theoretical examination of the economic rationality of consumption as it existed within the Mycenaean political economy. Using a modified paradigm of social network analysis, a semiotic approach is used in the study of identity expression and economic stratification present at three Late Helladic cemeteries. In doing so, the claim that exchange strategies which existed outside of palatial redistribution were present in the Late Helladic was substantiated as a similar logic of mortuary stratification which existed during the palatial era was also found to have existed after the shift to the post-palatial era and the collapse of …


Income Inequality And Oil Resources: Panel Evidence From The United States, Edmond Berisha, Carolyn Chisadza, Matthew Clance, Rangan Gupta Dec 2021

Income Inequality And Oil Resources: Panel Evidence From The United States, Edmond Berisha, Carolyn Chisadza, Matthew Clance, Rangan Gupta

Department of Economics Faculty Scholarship and Creative Works

The resource curse is sometimes associated with poor resource-rich countries. However, using panel evidence from the United States, we find that the resource curse is also prevalent in a wealthy resource-rich country. This study investigates the impact of oil resources on income inequality, with a particular focus on distinguishing between the effects from oil abundance (i.e. production) versus oil dependency (i.e. consumption). We observe contrasting non-monotonic outcomes from oil abundance in comparison to oil dependency. For oil abundance, states with low oil production will have less inequality if they increase oil production, and states with high oil production will have …


Implementing Big Data Analytics In Marketing Departments: Mixing Organic And Administered Approaches To Increase Data-Driven Decision Making, Devon S. Johnson, Debika Sihi Dec 2021

Implementing Big Data Analytics In Marketing Departments: Mixing Organic And Administered Approaches To Increase Data-Driven Decision Making, Devon S. Johnson, Debika Sihi

Department of Marketing Faculty Scholarship and Creative Works

This study examines the experience of marketing departments to become fully data-driven decision-making organizations. We evaluate an organic approach of departmental sensemaking and an administered approach by which top management increase the influence of analytics skilled employees. Data collection commenced with 15 depth interviews of marketing and analytics professionals in the US and Europe involved in the implementation of big data analytics (BDA) and was followed by a survey data of 298 marketing and analytics middle management professionals at United States based firms. The survey data supports the logic that BDA sensemaking is initiated by top management and is comprised …


Moral Encroachment And The Epistemic Impermissibility Of (Some) Microaggressions, Javiera Perez Gomez Dec 2021

Moral Encroachment And The Epistemic Impermissibility Of (Some) Microaggressions, Javiera Perez Gomez

Philosophy Faculty Research and Publications

A recent flurry of philosophical research on microaggression suggests that there are various practical and moral reasons why microaggression may be objectionable, including that it can be offensive, cause epistemic harms, express demeaning messages about certain members of our society, and help to reproduce an oppressive social order. Yet little attention has been given to the question of whether microaggression is also epistemically objectionable. This paper aims to further our understanding of microaggression by appealing to recent work on moral encroachment—the idea that knowledge is sensitive to the moral stakes of believing—to argue that microaggression can be irrational in a …


Investigations Of Potential Mechanisms Underlying Spinal Cord Injury-Induced Polyuria., Jason H. Gumbel Dec 2021

Investigations Of Potential Mechanisms Underlying Spinal Cord Injury-Induced Polyuria., Jason H. Gumbel

Electronic Theses and Dissertations

Spinal cord injury (SCI) results in neurological impairments including motor, sensory, and autonomic dysfunction. These neurological deficits result in a litany of complications apart from muscular paralysis, including bladder, bowel, cardiovascular, and sexual function. SCI-induced polyuria (the overproduction/passage of urine) remains understudied, and therefore mechanisms behind it are largely unknown and require extensive investigation for potential targeted therapies to improve quality of life. The objective of this dissertation was to investigate potential mechanisms of SCI-induced polyuria and explore potential therapies to improve quality of life in the SCI population. Metabolic cages, Western blot, enzyme-linked immunoassay, and immunostaining were first used …


Towards Long Term Colloid Suspension In A Vertically Rotated System., Md Mahmudur Rahman Dec 2021

Towards Long Term Colloid Suspension In A Vertically Rotated System., Md Mahmudur Rahman

Electronic Theses and Dissertations

Within a colloidal suspension gravity may compromise the observation of governing physical interactions, especially those that are weak and/or take significant time to develop. Conducting the experiment in a long-term microgravity environment is a viable option to negate gravitational effects, though significant resources are required to do so. While it may not be possible to simulate long-term microgravity terrestrially, particles can resist quick sedimentation in a confined suspension system rotating vertically with appropriate rotation speed. The goal of the investigation is to demonstrate the existence of long-term particle suspension regime for a certain colloidal suspension while characterizing colloidal behavior due …


Local Feature Selection For Multiple Instance Learning With Applications., Aliasghar Shahrjooihaghighi Dec 2021

Local Feature Selection For Multiple Instance Learning With Applications., Aliasghar Shahrjooihaghighi

Electronic Theses and Dissertations

Feature selection is a data processing approach that has been successfully and effectively used in developing machine learning algorithms for various applications. It has been proven to effectively reduce the dimensionality of the data and increase the accuracy and interpretability of machine learning algorithms. Conventional feature selection algorithms assume that there is an optimal global subset of features for the whole sample space. Thus, only one global subset of relevant features is learned. An alternative approach is based on the concept of Local Feature Selection (LFS), where each training sample can have its own subset of relevant features. Multiple Instance …


First Principle Studies Of The Effects Of Alkali-Metal Intercalation On Structural Transition From Black To Blue Phosphorene And The Adsorption Of N2h4 On Ws2 Layers., Md Rajib Khan Musa Dec 2021

First Principle Studies Of The Effects Of Alkali-Metal Intercalation On Structural Transition From Black To Blue Phosphorene And The Adsorption Of N2h4 On Ws2 Layers., Md Rajib Khan Musa

Electronic Theses and Dissertations

A comprehensive density functional theory calculation has been conducted to seek a potential structural transition from black to blue phosphorene layers, with a focus on the roles played by alkali-metal intercalation in black phosphorene/phosphorus. This study reveals that at sufficiently high Li concentration and specific, well-defined configurations, a phase transition from black to blue phosphorene can take place. The Li atoms intercalated in black phosphorene could act as a “catalyst” in the“reactive region” of the lone pair of P atoms, leading to a P-P bond breaking and, subsequently, a local structural transformation from an orthorhombic lattice to an assembly of …


A Remote Sensing Perspective: Mapping The Human Footprint In The Zambezi Region Of Namibia., Ariel E Weaver Dec 2021

A Remote Sensing Perspective: Mapping The Human Footprint In The Zambezi Region Of Namibia., Ariel E Weaver

Electronic Theses and Dissertations

The “human footprint” can be used as a general proxy to estimate human activities across the landscape. The human footprint in the Zambezi Region of Namibia is critically important for regional management of conservation efforts and land use planning. The land covers in the Zambezi Region are characteristically difficult to separate spectrally, due to a highly heterogeneous savanna landscape. Object Based Image Analysis (OBIA) and Random Forest (RF) methods are notable for their ability to improve classification accuracies of remotely sensed imagery. In this study, I investigate the extent of the human footprint in the Zambezi Region of Namibia, using …


Visualizing Anhydrobiosis: Liquid-Liquid Phase Separation, Membraneless Organelles, And Cellular Reorganization., Clinton J. Belott Dec 2021

Visualizing Anhydrobiosis: Liquid-Liquid Phase Separation, Membraneless Organelles, And Cellular Reorganization., Clinton J. Belott

Electronic Theses and Dissertations

Water is an integral and necessary component of life. It is then, exceedingly remarkable that some species are capable of surviving virtually complete water loss for extended periods of time. Several decades of intense research into anhydrobiosis, or life without water, have given significant insights into the molecular mechanisms governing this phenomenon. Anhydrobiosis-related intrinsically disordered (ARID) proteins have been demonstrated to be critically important for desiccation tolerance in many anhydrobiotic species and exhibit a considerably wide range of protective properties that include membrane stabilization, reinforcing bioglass formation, and protein stabilization. This dissertation begins with cellular dielectrophoresis suggesting that two ARID …


Decisive Neutrality, Restricted Decisive Neutrality, And Split Decisive Neutrality On Median Semilattices And Median Graphs., Ulf Högnäs Dec 2021

Decisive Neutrality, Restricted Decisive Neutrality, And Split Decisive Neutrality On Median Semilattices And Median Graphs., Ulf Högnäs

Electronic Theses and Dissertations

Consensus functions on finite median semilattices and finite median graphs are studied from an axiomatic point of view. We start with a new axiomatic characterization of majority rule on a large class of median semilattices we call sufficient. A key axiom in this result is the restricted decisive neutrality condition. This condition is a restricted version of the more well-known axiom of decisive neutrality given in [4]. Our theorem is an extension of the main result given in [7]. Another main result is a complete characterization of the class of consensus on a finite median semilattice that satisfies the axioms …


Design Of A 300cm2 Pemfc Stack With Force And Cfd Simulation To Optimize Flow Channels, Gasket Design, And Clamping Forces., Robert M. Ench Dec 2021

Design Of A 300cm2 Pemfc Stack With Force And Cfd Simulation To Optimize Flow Channels, Gasket Design, And Clamping Forces., Robert M. Ench

Electronic Theses and Dissertations

Proton exchange membrane fuel cells are important to the future of green energy as hydrogen can be made with green technologies and store energy for later use. Fuel cells can efficiently convert the hydrogen to electricity as needed. This study uses Solidworks simulation to make design improvements to the fuel cell before the prototype build stage of testing; this saves money and time by reducing the prototype builds needed.

In this study, a multi-channel serpentine design with two outlets versus a single outlet is evaluated using CFD to investigate pressure drop. Lower pressure drops are desirable as less energy input …


Translating Particulate Hexavalent Chomium-Induced Chromosome Instability, Loss Of Homologous Recombination Repair And Targeting Of Rad51 From Human Lung Fibroblasts To Human Bronchial Epithelial Cells., Idoia Meaza Isusi Dec 2021

Translating Particulate Hexavalent Chomium-Induced Chromosome Instability, Loss Of Homologous Recombination Repair And Targeting Of Rad51 From Human Lung Fibroblasts To Human Bronchial Epithelial Cells., Idoia Meaza Isusi

Electronic Theses and Dissertations

Particulate hexavalent chromium [Cr(VI)] is a well-established human lung carcinogen. RAD51, a key protein in homologous recombination repair pathway, is inhibited after prolonged exposure to Cr(VI), leading to an increase in chromosome instability after prolonged exposures in human lung fibroblasts. chromosome instability is the proposed driver of Cr(VI) carcinogenesis. Since tumors from chromate workers develop from epithelial cells, we sought to translate these findings from human bronchial fibroblasts to human bronchial epithelial cells. We hypothesized Cr(VI) inhibits RAD51 after prolonged exposure leading to an increase in chromosome instability in human bronchial epithelial cells (BEP2D). We characterized the cytotoxicity and measured …


Identification Of Disease-Linked Hyperactivating Mutations In Ube3a Through Large-Scale Functional Variant Analysis, Kellan P. Weston, Xiaoyi Gao, Jinghan Zhao, Kwang Soo Kim, Susan E. Maloney, Jill Gotoff, Sumit Parikh, Yen Chen Leu, Kuen Phon Wu, Marwan Shinawi, Joshua P. Steimel, Joseph S. Harrison, Jason J. Yi Dec 2021

Identification Of Disease-Linked Hyperactivating Mutations In Ube3a Through Large-Scale Functional Variant Analysis, Kellan P. Weston, Xiaoyi Gao, Jinghan Zhao, Kwang Soo Kim, Susan E. Maloney, Jill Gotoff, Sumit Parikh, Yen Chen Leu, Kuen Phon Wu, Marwan Shinawi, Joshua P. Steimel, Joseph S. Harrison, Jason J. Yi

College of the Pacific Faculty Articles

The mechanisms that underlie the extensive phenotypic diversity in genetic disorders are poorly understood. Here, we develop a large-scale assay to characterize the functional valence (gain or loss-of-function) of missense variants identified in UBE3A, the gene whose loss-of-function causes the neurodevelopmental disorder Angelman syndrome. We identify numerous gain-of-function variants including a hyperactivating Q588E mutation that strikingly increases UBE3A activity above wild-type UBE3A levels. Mice carrying the Q588E mutation exhibit aberrant early-life motor and communication deficits, and individuals possessing hyperactivating UBE3A variants exhibit affected phenotypes that are distinguishable from Angelman syndrome. Additional structure-function analysis reveals that Q588 forms a regulatory site …


A Global Agenda For Advancing Freshwater Biodiversity Research, Alain Maasri, Sonja C. Jähnig, Hendrik Freitag, 93 Co-Authors Dec 2021

A Global Agenda For Advancing Freshwater Biodiversity Research, Alain Maasri, Sonja C. Jähnig, Hendrik Freitag, 93 Co-Authors

Biology Faculty Publications

Global freshwater biodiversity is declining dramatically, and meeting the challenges of this crisis requires bold goals and the mobilisation of substantial resources. While the reasons are varied, investments in both research and conservation of freshwater biodiversity lag far behind those in the terrestrial and marine realms. Inspired by a global consultation, we identify 15 pressing priority needs, grouped into five research areas, in an effort to support informed stewardship of freshwater biodiversity. The proposed agenda aims to advance freshwater biodiversity research globally as a critical step in improving coordinated actions towards its sustainable management and conservation.


Synthesis Methodologies For Robust And Reconfigurable Clock Networks, Necati Uysal Dec 2021

Synthesis Methodologies For Robust And Reconfigurable Clock Networks, Necati Uysal

Electronic Theses and Dissertations, 2020-2023

In today's aggressively scaled technology nodes, billions of transistors are packaged into a single integrated circuit. Electronic Design Automation (EDA) tools are needed to automatically assemble the transistors into a functioning system. One of the most important design steps in the physical synthesis is the design of the clock network. The clock network delivers a synchronizing clock signal to each sequential element. The clock signal is required to be delivered meeting timing constraints under variations and in multiple operating modes. Synthesizing such clock networks is becoming increasingly difficult with the complex power management methodologies and severe manufacturing variations. Clock network …


Part-Time., Anthony Mark Piedmonte Dec 2021

Part-Time., Anthony Mark Piedmonte

Electronic Theses and Dissertations

This thesis is a creative writing project in prose covering the first 70 pages of a novel manuscript titled Part-time. Part-time will center around a 25-year-old medical school dropout starting a new job at a neighborhood golf clubhouse and gym. This coming-of-age narrative follows Danny as he struggles with his sexual identity, student debt, and job outlook after returning to the privileged community he grew up in. This sample will introduce the major characters, the clubhouse setting, and the forming relationship dynamics. By the end of these pages, readers will gain insight into how the part-time employees of the Longwood …


Literacy Abilities Of Children And Adolescents With Williams Syndrome., Caroline Greiner De Magalhaes Dec 2021

Literacy Abilities Of Children And Adolescents With Williams Syndrome., Caroline Greiner De Magalhaes

Electronic Theses and Dissertations

In this dissertation I report findings from two studies of the literacy abilities of children with Williams syndrome (WS), a genetic disorder associated with intellectual disability. I had two overarching goals: 1) evaluate the applicability of theories of reading and spelling acquisition developed based on typically developing children to children with WS; and 2) provide results that would inform the development of targeted assessments and interventions. In Study 1, individual differences in phonological awareness, visual spatial perception, vocabulary, overall intellectual abilities, and reading instruction approach (systematic phonics vs. other approaches) for sixty-nine 6 – 7-year-olds (most of whom were in …


Charting The Unknown: Examining The Prevalence And Correlates Of Seconday Traumatic Stress In Kentucky Probation And Parole Officers., Amanda Marie Roberts Dec 2021

Charting The Unknown: Examining The Prevalence And Correlates Of Seconday Traumatic Stress In Kentucky Probation And Parole Officers., Amanda Marie Roberts

Electronic Theses and Dissertations

The purpose of this dissertation was to discern the prevalence and magnitude of both exposure to traumatic events and Secondary Traumatic Stress (STS); as well as potential correlates of STS in a group of Probation and Parole officers in the state of Kentucky Department of Corrections (KY DOC). Participants (N=302) completed a written survey which asked them to indicate demographic variables (age, gender, and ethnicity), as well as several important occupational variables, namely years of experience in the KY DOC, caseload volume, prison work experience, and whether or not they are responsible for a sexual offender caseload. Participants were also …


Effects Of Chemosensory Experience And Context On Consummatory Behaviors., Saphira M. Chiu Dec 2021

Effects Of Chemosensory Experience And Context On Consummatory Behaviors., Saphira M. Chiu

Electronic Theses and Dissertations

Eating food generates associations between odors and tastes (i.e., flavor) that guide future choices. Experience with an odor-taste mixture links an odor with a taste’s quality and hedonic value, resulting in a preference for an odor paired with a palatable taste over an odor paired with an unpalatable taste. However, experience with a neutral stimulus (i.e., latent inhibition) or environment (i.e., context) can influence the formation of conditioned associations. Here, I used a two-bottle brief-access task to determine whether rats display an innate preference between unpaired odors (isoamyl acetate and benzaldehyde), how preexposure to the unpaired odors impacts mixture-dependent consummatory …


Video Error Concealment Using Convolutional Neural Network, Shashi Khanal Dec 2021

Video Error Concealment Using Convolutional Neural Network, Shashi Khanal

Graduate Theses/Dissertations

Missing information in the video frames is estimated as close as possible to the actual data during video error concealment process. Blocks or slices of information in the video frames can be missing in the decoder due to various reasons like corrupt media drives, network congestion, etc. which reduces the quality of experience for the viewers. One approach to deal with missing information in the video decoder is to use error concealment techniques to fill the missing information. Until now many of these error concealment techniques were based on conventional methods such as block copy, motion vector prediction, and interpolation. …


Boxed In: Hinge Closing Performance Of Ornate Box Turtles (Terrapene Ornata), Gina L. Buelow Dec 2021

Boxed In: Hinge Closing Performance Of Ornate Box Turtles (Terrapene Ornata), Gina L. Buelow

Graduate Theses/Dissertations

Turtles are perhaps best known for the bony shells that encase them, a unique morphological trait that provides protection against predators. Many taxa have even evolved the ability to enclose themselves using hinges that can be used to create a seal between the carapace and plastron. I measured the hinge closing force of Ornate Box Turtles (Terrapene ornata) to assess the performance of this unusual yet ecologically important trait. I sampled head-started turtles from Thomson Sand Prairie in the Upper Mississippi River National Wildlife and Fish Refuge and wild turtles collected in northern Oklahoma. To assess the effects of head-starting …


Effects Of "Lemongrass Factor" On Galleria Mellonella Hemocytes, Jennifer C. Rice Dec 2021

Effects Of "Lemongrass Factor" On Galleria Mellonella Hemocytes, Jennifer C. Rice

Graduate Theses/Dissertations

The use of conventional chemical insecticides to control agricultural pest has become problematic as they may have a negative impact towards human health and the environment, resulting in a need to research alternative methods to insect pest control. Plant derived substances like essential oils have been used for generations as toxicants, repellants, and anti-feedants to control agricultural pest. More research is needed to understand how insect immune systems react to essential oils and if cellular immune responses of phagocytosis, encapsulation, and nodulation can be inhibited by such. Subjecting Galleria mellonella to various concentrations of “lemongrass factor” lets the researcher/scientist know …


Geochemical Investigation Of Monogenetic Volcanoes From The Pribilof Islands, Bering Sea, Alaska, Clayton L. Reinier Dec 2021

Geochemical Investigation Of Monogenetic Volcanoes From The Pribilof Islands, Bering Sea, Alaska, Clayton L. Reinier

Graduate Theses/Dissertations

Small-volume basaltic magmas found at continental intraplate environments have not been as extensively studied compared to their polygenetic counterparts. Specifically, regions such as the Bering Sea basalt province, described as a diffuse igneous province, have commonly been overlooked. Assumptions that these systems are invoked by simple, single batches of magma has subsequently left a gap in understanding the processes responsible for primary magma generation away from plate boundaries with little tectonic influence. The following studies that constitute this thesis focus on an in-depth geochemical investigation at the crystal and sub-crystal scale to evaluate lithospheric mantle heterogeneities, processes that govern primary …