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Anemia Among Women Of Reproductive Age: An Overview Of Global Burden, Trends, Determinants, And Drivers Of Progress In Low- And Middle-Income Countries, Aatekah Owais, Catherine Merritt, Christopher Lee, Zulfiqar Ahmed Bhutta

Centre of Excellence in Women and Child Health

Relatively little progress has been made in reducing anemia prevalence among women of reproductive age (WRA anemia). Interventions, policies and programs aimed at reducing WRA anemia have the potential to improve overall not only women's, but also children's health and nutrition outcomes. To our knowledge, this is the first review that aimed to compile evidence on the determinants and drivers of WRA anemia reduction in low- and middle-income countries (LMICs). We synthesized the available evidence on the determinants and drivers, including government policies and programs, of WRA anemia and their mitigation strategies across a wide range of countries and geographies, …

Moderate Plant–Soil Feedbacks Have Small Effects On The Biodiversity–Productivity Relationship: A Field Experiment, Josephine Grenzer, Andrew Kulmatiski, Leslie Forero, Anne Ebeling, Nico Eisenhauer, Jeanette Norton

Wildland Resources Student Research

Plant–soil feedback (PSF) has gained attention as a mechanism promoting plant growth and coexistence. However, most PSF research has measured monoculture growth in greenhouse conditions. Translating PSFs into effects on plant growth in field communities remains an important frontier for PSF research. Using a 4-year, factorial field experiment in Jena, Germany, we measured the growth of nine grassland species on soils conditioned by each of the target species (i.e., 72 PSFs). Plant community models were parameterized with or without these PSF effects, and model predictions were compared to plant biomass production in diversity–productivity experiments. Plants created soils that changed subsequent …

Pgc1Α Is Required For The Renoprotective Effect Of Lncrna Tug1 In Vivo And Links Tug1 With Urea Cycle Metabolites, Daniel L Galvan, Paul A Overbeek, Lin Tan, Shwetha V Kumar, Wai Kin Chan, Phillip L Lorenzi, Benny H Chang, Farhad R Danesh

Faculty, Staff and Students Publications

lncRNA taurine-upregulated gene 1 (Tug1) is a promising therapeutic target in the progression of diabetic nephropathy (DN), but the molecular basis of its protection remains poorly understood. Here, we generate a triple-mutant diabetic mouse model coupled with metabolomic profiling data to interrogate whether Tug1 interaction with peroxisome proliferator-activated receptor gamma coactivator 1α (PGC1α) is required for mitochondrial remodeling and progression of DN in vivo. We find that, compared with diabetic conditional deletion of Pgc1α in podocytes alone (db/db; Pgc1αPod-f/f), diabetic Pgc1α knockout combined with podocyte-specific Tug1 overexpression (db/db; TugPodTg; Pgc1αPod-f/f) reverses the protective phenotype of …

Adipose Tissue Hyaluronan Production Improves Systemic Glucose Homeostasis And Primes Adipocytes For Cl 316,243-Stimulated Lipolysis, Mason Bartels, Sophie Dogné, Shangang Zhao, Xi Chen, Clair Crewe, Leon Straub, Lavanya Vishvanath, Zhuzhen Zhang, Mengle Shao, Yongjie Yang, Christy M Gliniak, Ruth Gordillo, Gordon I Smith, William L Holland, Rana K Gupta, Bingning Dong, Nathalie Caron, Yong Xu, Yucel Akgul, Samuel Klein, Philipp E Scherer

Faculty, Staff and Students Publications

Plasma hyaluronan (HA) increases systemically in type 2 diabetes (T2D) and the HA synthesis inhibitor, 4-Methylumbelliferone, has been proposed to treat the disease. However, HA is also implicated in normal physiology. Therefore, we generated a Hyaluronan Synthase 2 transgenic mouse line, driven by a tet-response element promoter to understand the role of HA in systemic metabolism. To our surprise, adipocyte-specific overproduction of HA leads to smaller adipocytes and protects mice from high-fat-high-sucrose-diet-induced obesity and glucose intolerance. Adipocytes also have more free glycerol that can be released upon beta3 adrenergic stimulation. Improvements in glucose tolerance were not linked to increased plasma …

Gaiety, April 1976

Gaiety, 1975-1977

Editor-in-Chief: Gary Poe. News Editor: Fred Harris. Staff Writers: Martha Brummett, Buddy Haynes. Staff Artist: Mary Jo Cowart. Jackson (TN) Correspondent: Wayne Maness.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Gaiety, October 1975

Gaiety, 1975-1977

Co-Editors: Gary Poe, Lila Baker. News Editor: Fred Harris. Graphics: Jim Alley

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

A Single Cell Pair Mechanical Interrogation Platform To Study Cell–Cell Adhesion Mechanics, Amir Monemianesfahani

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Cell-cell adhesion complexes are macromolecular adhesive organelles that integrate cells into tissues. Perturbations of the cell-cell adhesion structure or relatedmechanotransduction pathways lead to pathological conditions such as skin and heart diseases, arthritis, and cancer. Mechanical stretching has been used to stimulate the mechanotransduction process originating from the cell-cell adhesion and cell-extracellular matrix (ECM) complexes. The current techniques, however, have limitations on their ability to measure the cell-cell adhesion force directly and quantitatively. These methods use a monolayer of cells, which makes it impossible to quantify the forces within a single cell-cell adhesion complex. Other methods using single cells or cell …

The New American Dream: Neoliberal Transformation As Character Development In Schitt’S Creek, William Joseph Sipe

Department of Communication Studies: Faculty Publications

This article contextualizes the popular sitcom Schitt’s Creek within an era of unprecedented economic inequality and growing distain for the ultrawealthy. Via its over-the-top and self-effacing humor, the program invites audiences to discipline the Rose family for their former life of leisure and ultimately celebrate as each character is transformed into an ideal neoliberal subject via economic precarity and entrepreneurism. Through an analysis of the show’s 6 seasons, this essay articulates how the myth of the American Dream has adapted to neoliberal ideology that prizes precarity as a state of possibility and rejects leisure as laziness. Schitt’s Creek is emblematic …

Flip: An Interaction Design Project For Helping People To Break Echo Chamber, Rong Zhao

Theses

Social media constantly instills you with the things you like and the things you are willing to believe in, even disinformation, creating an echo chamber in which users will never have other opinions. People are controlled by algorithms so that social media platforms ensure we only get a single side of every story. The personalization of social media minimizes people's view of the world and causes the division of society. My thesis explores the interaction methods to encourage people to be exposed to multiple perspectives about things by reading the same story from different sources. To solve the problem, I …

Do Early-Successional Weeds Facilitate Or Compete With Seedlings In Forest Restoration? Disentangling Abiotic Versus Biotic Factors, Mylen Arias, Rupesh R. Kariyat, Kimberly Wahl-Villarreal, Stephany Mendez, Jesus Chavana, Bradley O. Christoffersen

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

1. Semi-arid forests need cost-effective restoration strategies to address their severe degradation. Tree shelters are often used to minimize abiotic and biotic stress during seedling establishment. We asked if early-successional weeds act as a natural shelter by facilitating native seedlings, contingent on abiotic and biotic stressors and seedling ecological strategy.

2. We conducted a manipulative weed exclusion experiment at a semi-arid site in South Texas targeted for large-scale forest restoration to discern the net effect of weeds on the growth and survival of target thornscrub tree and shrub seedlings. We assessed the roles of contrasting seedling ecological strategies (fast vs. slow growth …

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Performance And Locus Of Control Of Small Farmers In Yunnan Province, Alan Mcdermott

IGC Proceedings (1977-2023)

No abstract provided.

Mission Concept For Demonstrating Small-Spacecraft True Anomaly Estimation Using Millisecond X-Ray Pulsars, Anant Kandala, Aashka Oza, Bharath Saiguhan, Shreya Mishra, Priyadarshnam Hari, Samir Mandal, Harsh Simha

Small Satellite Conference

Navigation based on X-ray pulsars was first suggested in 1981 for deep space navigation as an alternative to the conventional Deep Space Network (DSN) which is inaccurate at large distances from the Earth. This idea was recently demonstrated using the NICER/SEXTANT instrument onboard the ISS. X-ray pulsar-based navigation is of of great interest as it eliminates the reliance on Earth-based systems, and is yet to be implemented as an autonomous navigation system for deep space missions. For the purpose of navigation, X-ray millisecond pulsars are the most appropriate celestial sources. They emit unique, stable and periodic radiation that exhibits high …

A Sat-To-Sat Inspection Demonstration With The Aerocube-10 1.5u Cubesats, Joseph W. Gangestad, Catherine C. Venturini, David A. Hinkley, Garrett Kinum

Small Satellite Conference

In the summer of 2020, the pair of AeroCube-10 1.5U CubeSats completed a series of mutual proximity operations as close as 22 meters separation and captured several sets of satellite-to-satellite resolved imagery, inspecting all faces of a vehicle in each pass with a resolution less than 8 mm. AeroCube-10 was designed and built by The Aerospace Corporation with the primary missions of atmospheric science and the maturation of nanosatellite technologies, including a new star tracker design, warm-gas propulsion system, GPS receiver, and a low-noise focal plane. Investigating the possibility of using CubeSats for satellite inspection missions, the AeroCube-10 team designed …

Design And Testing Of Autonomous Distributed Space Systems, Nicholas Cramer, Daniel Cellucci, Caleb Adams, Adam Sweet, Mohammad Hejase, Jeremy Frank, Richard Levinson, Sergei Gridnev, Lara Brown

Small Satellite Conference

Distributed Space Systems (DSS) are an emerging class of mission designs that enable new scientific and commercial opportunities. In order to enable those new opportunities, these systems will need to have significantly expanded autonomous capabilities compared to their single-spacecraft predecessors. In this paper, we present Distributed Spacecraft Autonomy (DSA) project, a payload on NASA’s Starling spacecraft experiment. We first describe a step-by-step process for characterizing what features are needed in an autonomous DSS, and show how this process applied to DSA. We then describe the Starling mission, a four-spacecraft swarm hosting multiple DSS payloads. We then describe DSA, which will …

Volume 34, Numbers 1, 2, 3, 4, Fall 1996/Winter 1997/Spring 1997/Summer 1997 Speaker And Gavel

Speaker & Gavel

Complete digitized volume (volume 34, numbers 1-4, Fall 1996/Winter 1997/Spring 1997/Summer 1997) of Speaker & Gavel.

Volume 31, Numbers 1, 2, 3, 4, Fall 1993/Winter 1994/Spring 1994/Summer 1994

Speaker & Gavel

Complete digitized volume (volume 31, numbers 1-4, Fall 1993/Winter 1994/Spring 1994/Summer 1994) of Speaker & Gavel.

Volume 30, Numbers 1, 2, 3, 4, Fall 1992/Winter 1993/Spring 1993/Summer 1993 Speaker And Gavel

Speaker & Gavel

Complete digitized volume (volume 30, numbers 1-4, Fall 1992/Winter 1993/Spring 1993/Summer 1993) of Speaker & Gavel.

Asian American Undergraduates Sense Of Belonging At A Predominantly White Institution, Miso Jang

M.A. in Higher Education Leadership: Action Research Projects

In the fall of 2019, institutionalized data reported that Asian American undergraduate students had a lower sense of belonging at the University of San Diego (USD) in comparison to white peers. This action research paper explores the needs and experiences of the Asian American undergraduate student population at USD— a predominantly white, private, religious-based institution. This research is centered around the question, “How can Student Affairs professionals better understand and support Asian American undergraduate students and their sense of belonging at a predominantly White institution?” Through ten semi-structured interviews and one community focus group, participating students associated their sense of …

El Testimonio Literario Traducido: Retos Y Desafíos., Jocelyn Madelein Silva

Theses and Dissertations

Translation is one of the oldest professions in the history of humanity. Without it, it would be impossible to access other civilizations historical, social, and cultural records. The most translated text worldwide is the Bible. One of the literary genres that has not received much attention is the testimony. This literary genre is important because it provides a voice to those who do not have it. In this thesis, four testimonies from Puentes, a Mexican-Chicano journal of literature, culture, and art, are translated into Spanish. Besides the translations, this thesis addresses the history of translation and the testimony as a …

Episode 6: Kate Mansfield: Turtle Research And Marine Biology, University Of Central Florida

Knights Do That Podcast Transcripts

In this week’s Knights Do That episode, we speak with Davis-Schein Endowed Professor in Conservation Biology Kate Mansfield. She is a marine scientist who is the lab director for the UCF Marine Turtle Research Group and graduate coordinator for UCF's Department of Biology in the College of Sciences.

In this episode, we learn how Mansfield got into this field, some of the coolest things that she’s discovered over the years and what hands-on experiences for her students look like.

Produced by UCF, the podcast highlights students, faculty, staff, administrators and alumni who do incredible things on campus, in the community …

The Problem Of Heaven With Dr. Kevin Timpe, Kevin Timpe

University Faculty Publications and Creative Works

No abstract provided.

Roles Of A Bradykinin Storm And A Cytokine Storm In Covid-19 Cases, Nouha H. Odeh

Honors College Theses

In the light of recent events, it is imperative to understand the key inflammatory response elements that appear to be the source of more severe ailments resulting from a SARS-CoV-2 viral infection known as Covid-19 The more severe cases of Covid-19 are characterized by a severe inflammatory response resulting in tissue damage. My research proposal aims to investigate the two possible culprits of this response: a bradykinin (BK) storm and an interleukin-6 (IL-6) mediated cytokine storm. In both systems respectively, the excess release of these signals subsequently signals the production of even more of the same response element, resulting in …

Modulation Of The Effects Of Class Ib Antiarrhythmics On Cardiac Nav1.5-Encoded Channels By Accessory Navβ Subunits, Wandi Zhu, Wei Wang, Paweorn Angsutararux, Rebecca L. Mellor, Lori L. Isom, Jeanne M. Nerbonne, Jonathan R. Silva

Open Access Publications

Native myocardial voltage-gated sodium (NaV) channels function in macromolecular complexes comprising a pore-forming (α) subunit and multiple accessory proteins. Here, we investigated the impact of accessory NaVβ1 and NaVβ3 subunits on the functional effects of 2 well-known class Ib antiarrhythmics, lidocaine and ranolazine, on the predominant NaV channel α subunit, NaV1.5, expressed in the mammalian heart. We showed that both drugs stabilized the activated conformation of the voltage sensor of domain-III (DIII-VSD) in NaV1.5. In the presence of NaVβ1, the effect of lidocaine on the DIII-VSD was enhanced, whereas the effect of ranolazine was abolished. Mutating the main class Ib …

Taspase1 Orchestrates Fetal Liver Hematopoietic Stem Cell And Vertebrae Fates By Cleaving Tfiia, Hidetaka Niizuma, Adam C. Searleman, Shugaku Takeda, Scott A. Armstrong, Christopher Y. Park, Emily H. Cheng, James J. Hsieh

Open Access Publications

Taspase1, a highly conserved threonine protease encoded by TASP1, cleaves nuclear histone-modifying factors and basal transcription regulators to orchestrate diverse transcription programs. Hereditary loss-of-function mutation of TASP1 has recently been reported in humans as resulting in an anomaly complex syndrome, which manifests with hematological, facial, and skeletal abnormalities. Here, we demonstrate that Taspase1-mediated cleavage of TFIIAα-β, rather than of MLL1 or MLL2, in mouse embryos was required for proper fetal liver hematopoiesis and correct segmental identities of the axial skeleton. Homozygous genetic deletion of Taspase1 disrupted embryonic hematopoietic stem cell self-renewal and quiescence states and axial skeleton fates. Strikingly, mice …

The Olympics Look Back Part Ii, Richard C. Crepeau

On Sport and Society

As the 2008 Games approached, there was fear that air pollution in Beijing would cast a pall over the games. Essentially what happened was the rulers of the People’s Republic ordered the pollution to go away.

New Forces Influencing Savanna Conservation: Increasing Land Prices Driven By Gentrification And Speculation At The Landscape Scale, Peter Tyrrell, Robin Naidoo, David W. Macdonald, Johan T. Du Toit

Wildland Resources Faculty Publications

Land transformation reduces biodiversity and regional sustainability, with land price being an indicator of the opportunity cost to a landowner of resisting land conversion. However, reliable spatially explicit databases of current land prices are generally lacking in developing countries. We used tools from data science to scrape 1,487 georeferenced land prices in southern Kenya from the internet. Prices were higher for land near cities and in areas of high agricultural productivity, but also around the Maasai Mara National Reserve. Predicted land prices ranged from US$662 to US$4,618,805 per acre. Land speculation associated with expanding urbanization increases the opportunity and acquisition …

Dean's Spotlight August 9, 2021, Seattle University School Of Law Dean

Dean's Spotlight

No abstract provided.

Clinical And Epidemiological Features Of Acute Zika Virus Infections In León, Nicaragua, Natalie M. Bowman, Filemón Bucardo, Matthew H. Collins, Yaoska Reyes, Edwing Centeno Cuadra, Bryan Blette, Premkumar Lakshmanane, Enrique Paulo Guerra, Rebecca Rubinstein, Guei-Jiun Alice Liou, Aravinda M. De Silva, Sylvia Becker-Dreps

Student Publications

The American Zika virus (ZIKV) epidemic has highlighted the need to gain a better understanding of this emerging virus. The goal of this study was to describe the clinical symptoms, laboratory findings, and risk factors for symptomatic ZIKV infection in an area with ongoing transmission of other arboviral infections. We recruited patients at least 2 years of age seeking care at public health centers in León, Nicaragua, between January 2016 and August 2017, for fever, maculopapular rash, and/or nonsuppurative conjunctivitis with a duration of less than 1 week. A laboratory diagnosis of ZIKV was established using a combination of molecular …

Assessing The Short-Term Effects Of Translocation On Freshwater Mussels: Is Habitat Or Water Quality More Important?, Joshua D. Arnold

Masters Theses

Freshwater mussels (Order: Unionida) are very important to the function of aquatic ecosystems and are typically indicators of good water quality. They provide a valuable link between the water column and the benthic substrate in which they live and are a valuable food resource for many species of animals. However, most species native to North America are currently threatened with extinction, to the point that more than 70% of native freshwater mussels are listed as either threatened or endangered at the state or federal level. The cause of this decline can be attributed to historical over exploitation, habitat alteration, and …

Gaiety, July 1975

Gaiety, 1975-1977

Gary Poe, Editor. Martha Brummet, Production. Michael Maurer, Graphics.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.