Digital Commons Network^™

Effects Of Intermittent Fasting On Cognition And Neurodegeneration, Dureshahwar Kanwar, Mohammad Wasay

Pakistan Journal of Neurological Sciences (PJNS)

Intermittent fasting (IF) can facilitate neurodegenerative, neuroadaptive and neuroprotective processes leading to profound effects on cognition and dementias. The impact that IF has on the central nervous system is still not fully known. Several factors come into likely effect including changes in energy metabolism, oxidative damage, insulin sensitivity, inflammation, and functional changes related to various neurotransmitters and hormones. During IF ketones are produced in large quantities and the brain consumes these for energy. The presence of ketone bodies increases the expression of the genes for brain derived neurotrophic factor which has a powerful effect on dementia and cognition. Brain derived …

Assessing The Water Quality Of Three Bar-Built Estuaries In The Central Coast Of California, Micaelina Sarmiento Martinez

Master of Science in Environmental Sciences and Management Projects

Estuaries are coastal confluences with innumerable ecosystem services. With the continuous change in land use including the increasing number of people moving to live in coastal areas and on-going agricultural operations, these coastal systems are being adversely impacted. Climate change is also negatively affecting estuaries. Subsequently, this research study assessed the water quality, monthly, at three different locations of three bar-built estuaries in the Central Coast of California. Water quality was evaluated by the change in chlorophyll-a, nitrogen, phosphorus, pH, temperature, dissolved oxygen, and specific conductivity over the course of 19 months. The eutrophication potential and the role of open …

Quantification Of Marine Acoustic Environments, Dylan Charles Wilford

Master's Theses and Capstones

The soundscape is an acoustic environment made up of all sounds arriving at a receiver. A methodology for the analysis of soundscapes was developed in an attempt to facilitate efficient and accurate soundscape comparisons across time and space. The methodology included generating and combining results from a collection of traditional soundscape metrics, statistical measures, and acoustic indices that were selected to quantify several salient properties of marine soundscapes: amplitude, impulsiveness, periodicity, and uniformity. The metrics were calculated using approximately 30 hours using semi-continuous passive acoustic data gathered in seven unique acoustic environments. The calculated values for each candidate metric were …

Impact Of National And Municipal Environmental Standards On The Development Of Effective Solid Waste Management Systems In Jeddah, Kingdom Of Saudi Arabia, Raed Bin Sadan

Dissertations & Theses

The following research paper analyzes the impact of national and municipal environmental standards on the development of effective Solid waste management systems in Jeddah, Kingdom of Saudi Arabia. The research is essential in ensuring that there are notable positive changes in the disposal of solid waste by both the local government and the national government of the Kingdom of Saudi Arabia. The following paper follows a strategic plan and procedure in ensuring achievement of the goal and purpose of the research. The approach used in this paper is a comparison of the current local system and a proposed improvement of …

September 2021 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Tick Salivary Gland Extract Induces Alpha-Gal Syndrome In Alpha-Gal Deficient Mice, Shailesh K. Choudhary, Shahid Karim, Onyinye I. Iweala, Shivangi Choudhary, Gary Crispell, Surendra Raj Sharma, Claire T. Addison, Mike Kulis, Brian H. Herrin, Susan E. Little, Scott P. Commins

Faculty Publications

Introduction: Alpha-gal syndrome (AGS) is characterized by delayed hypersensitivity to non-primate mammalian meat in people having specific immunoglobulin E (sIgE) to the oligosaccharide galactose-alpha-1,3-galactose. AGS has been linked to tick bites from Amblyomma americanum (Aa) in the U.S. A small animal model of meat allergy is needed to study the mechanism of alpha-gal sensitization, the effector phase leading to delayed allergic responses and potential therapeutics to treat AGS.

Methods: Eight- to ten-weeks old mice with a targeted inactivation of alpha-1,3-galactosyltransferase (AGKO) were injected intradermally with 50 μg of Aa tick salivary gland extract (TSGE) on days …

Cripping The Welfare Queen: The Radical Potential Of Disability Politics, Jina B. Kim

English Language and Literature: Faculty Publications

Drawing together feminist- and queer-of-color critique with disability theory, this essay offers a literary-cultural reframing of the welfare queen in light of critical discourses of disability. It does so by taking up the discourse of dependency that casts racialized, low-income, and disabled populations as drains on the state, reframing this discourse as a potential site of coalition among antiracist, anticapitalist, and feminist disability politics. Whereas antiwelfare policy cast independence as a national ideal, this analysis of the welfare mother elaborates a version of disability and women-of-color feminism that not only takes dependency as a given but also mines the figure …

Data From A Public–Industry Partnership For Enhancing Corn Nitrogen Research, Curtis J. Ransom, Jason Clark, Gregory Mac Bean, Chris Bandura, Matthew E. Shafer, Newell R. Kitchen, Et.Al

Agronomy, Horticulture and Plant Science Faculty Publications

Improving corn (Zeamays L.) N managementis pertinent to economic andenvironmental objectives. However, there are limited comprehensive data sources to develop and test N fertilizer decision aid tools across a wide geographic range of soil and weather scenarios. Therefore, a public-industry partnership was formed to conduct standardized corn N rate response field studies throughout the U.S. Midwest. This research was conducted using a standardized protocol at 49 site-years across eight states over the 2014–2016 growing seasons with many soil, plant, and weather related measurements. This note provides the data (found in supplemental files), outlines the data, summarizes key findings, and highlights …

Nepalese In Denmark: How Their International Education Aspirations Transformed Into A Quest For ‘Greener Pasture’

Journal of Comparative & International Higher Education

No abstract provided.

Banning Imports Of Hunting Trophies And Protecting Endangered Wildlife, Stephen Hernick

Denver Journal of International Law & Policy

No abstract provided.

Vol. 50, No. 1: Title Page, Denver Journal Of International Law & Policy

Denver Journal of International Law & Policy

No abstract provided.

Vol. 50, No. 1: Full Issue, Denver Journal Of International Law & Policy

Denver Journal of International Law & Policy

No abstract provided.

Relationship Between Sexual Activity, Contraceptive Utilization And Biopsychosocial Characteristics Among Homeless Shelter Adolescents., Brittney A Gaudet, Nina Liu, Allison N Kayne, Taylor L Jarvill, Cecilia Zemanek, Jeffrey M Downen, Hoonani M Cuadrado, Amy B Smith, Marna R Greenberg, Jessica L Jacoby, Joanne N Quinones

Department of Emergency Medicine

Objective: To determine whether biopsychosocial factors are associated with sexual activity and contraceptive utilization among homeless shelter adolescents. Methods: A retrospective study of 440 adolescents at a shelter in Pennsylvania between February 2015 and September 2019 was conducted. The cohort was evaluated to determine what relationship age, gender identity, substance use, and trauma history have with sexual activity and contraceptive utilization. Results: Sexual activity was significantly related to age (mean 15.8+1.4 years in sexually active vs. 14.7+1.6 years in abstinent youth, p<0.001); remote history of self-harm behavior (relative risk ratio (RR) 1.23 [95% CI 1.03-1.46]; p=0.02), history of aggressive behavior (RR 1.21 [95% CI 1.01-1.46]; p=0.04), history of trauma (RR 1.24 [95% CI 1.04-1.48]; p=0.03), and substance use (RR 2.27 [95%CI 1.86-2.77]; p<0.001). There were 55.7% sexually active females vs. 42.50% males reporting contraception use (p=0.01). After adjustment, older age and substance use remained significantly associated with sexual activity (adjusted odds ratio (AOR) 1.58 [95% CI 1.36-1.83]; p<0.001 and AOR 5.18 [95% CI 3.28-8.18]; p<0.001, respectively). Conclusions: Females self-reported sexual activity using contraception more than males. After adjustment, older age and substance use were associated with sexual activity. By better understanding the impact these factors can have on contraceptive utilization, informed policy and practice interventions can be developed and implemented to help increase safe sex practices in spaces where homeless adolescents access healthcare.

Ipo Newsletter, September 2021, State University Of New York College At Cortland

International Programs

Newsletter of the International Programs Office including information for study abroad, international students at SUNY Cortland, and contact information.

Tennessee Farm Bureau News - September 2021, Tennessee Farm Bureau Federation

Tennessee Farm Bureau News

No abstract provided.

The Effect Of Project-Based Learning (Pjbl) Learning Model On Students' Science Process Skills On Colloidal Topics, Nurbani Jusuf, Anugrah Ricky Wijaya, I Wayan Dasna

Jurnal Pendidikan Sains

This study focused on the application of a Project-Based Learning (PjBL) model in chemistry learning using local wisdom from the Ternate area and examined the differences in students’ science process skills between those taught using the Project-Based Learning model and those taught using conventional learning models on colloidal topics, viewed from achievement motivation. The study employed a quasi-experimental design with a posttest-only groups design. The sample in this study consisted of students from one of the MAN schools in Ternate City. The results showed that there was a significant difference in students’ science process skills and achievement motivation between the …

Montanan, Fall 2021, University Of Montana--Missoula

Montanan Magazine, 1969-2024

This is the magazine of the University of Montana with news about the University for UM alumni as well as current faculty, students, staff, and administrators. This is volume 38.

Antimicrobial Resistance: A Challenge Awaiting The Post-Covid-19 Era, Tekle Airgecho Lobie, Aklilu Abrham Roba, James Alexander Booth, Knut Ivan Kristiansen, Abraham Aseffa, Kirsten Skarstad, Magnar Bjørås

Research on Antimicrobial Resistance

Microbe exposure to pharmaceutical and non-pharmaceutical agents plays a role in the development of antibiotic resistance. The risks and consequences associated with extensive disinfectant use during the COVID-19 pandemic remain unclear. Some disinfectants, like sanitizers, contain genotoxic chemicals that damage microbial DNA, like phenol and hydrogen peroxide. This damage activates error-prone DNA repair enzymes, which can lead to mutations that induce antimicrobial resistance. Public health priority programs that have faced drug-resistance challenges associated with diseases, such as tuberculosis, HIV, and malaria, have given less attention to risks attributable to the COVID-19 pandemic. Pathogen-specific programs, like the directly observed treatment strategy …

Parent–Child Joint Behaviors In Novel Object Play Create High‐Quality Data For Word Learning, C Chen, Dm Houston, C Yu

School of Psychology

This research takes a dyadic approach to study early word learning and focuses on toddlers’ (N = 20, age: 17–23 months) information seeking and parents’ information providing behaviors and the ways the two are coupled in real-time parent–child interactions. Using head-mounted eye tracking, this study provides the first detailed comparison of children’s and their parents’ behavioral and attentional patterns in two free-play contexts: one with novel objects with to-be-learned names (Learning condition) and the other with familiar objects with known names (Play condition). Children and parents in the Learning condition modified their individual and joint behaviors when encountering novel objects …

Tcf7l2 Genetic Variants Do Not Influence Insulin Sensitivity Or Secretion Indices In Autoantibody-Positive Individuals At Risk For Type 1 Diabetes, Maria J Redondo, Megan V Warnock, Ingrid M Libman, Laura E Bocchino, David Cuthbertson, Susan Geyer, Alberto Pugliese, Andrea K Steck, Carmella Evans-Molina, Dorothy Becker, Jay M Sosenko, Fida Bacha, Type 1 Diabetes Trialnet Study Group

Children’s Nutrition Research Center Staff Publications

Objective: We aimed to test whether type 2 diabetes (T2D)-associated TCF7L2 genetic variants affect insulin sensitivity or secretion in autoantibody-positive relatives at risk for type 1 diabetes (T1D).

Research design and methods: We studied autoantibody-positive TrialNet Pathway to Prevention study participants (N = 1,061) (mean age 16.3 years) with TCF7L2 single nucleotide polymorphism (SNP) information and baseline oral glucose tolerance test (OGTT) to calculate indices of insulin sensitivity and secretion. With Bonferroni correction for multiple comparisons, P values < 0.0086 were considered statistically significant.

Results: None, one, and two T2D-linked TCF7L2 alleles were present in 48.1%, 43.9%, and 8.0% of the participants, respectively. Insulin sensitivity …

The Role Of Gip Receptor In The Cns For The Pathogenesis Of Obesity, Makoto Fukuda

Children’s Nutrition Research Center Staff Publications

Glucose-dependent insulinotropic polypeptide (GIP) (also known as gastric inhibitory polypeptide) is a hormone produced in the upper gut and secreted to the circulation in response to the ingestion of foods, especially fatty foods. Growing evidence supports the physiological and pharmacological relevance of GIP in obesity. In an obesity setting, inhibition of endogenous GIP or its receptor leads to decreased energy intake, increased energy expenditure, or both, eventually causing weight loss. Further, supraphysiological dosing of exogenous long-lasting GIP agonists alters energy balance and has a marked antiobesity effect. This remarkable yet paradoxical antiobesity effect is suggested to occur primarily via the …

Using A Community Of Inquiry Framework To Make The Transition To Teaching Law Online, Audrey Fried

Journal of Legal Education

No abstract provided.

Full Circle: From Disabled Law Student To Law Professor, Katherine Pérez

Journal of Legal Education

No abstract provided.

The Power Of Presence In Socratic Teaching: The Effect Of Substituting Videoconferencing For In-Person Classes, William S. Blatt

Journal of Legal Education

No abstract provided.

Current Status Of Non-Disease Modifying Gene Therapy In Parkinson’S Disease, Muhammad Shariq Shaikh, Syed Ahsan Ali, Dureshahwar Kanwar

Pakistan Journal of Neurological Sciences (PJNS)

Parkinson’s disease (PD) is a chronic progressive neurological disorder characterized by bradykinesia, tremor, muscular rigidity, and postural instability. The world-wide prevalence is expected to rise further with increasing mean age. Theoretically, if all desired elements required for dopamine synthesis are functionally available, need for exogenous L-DOPA administration can be eliminated or markedly reduced. However, lack of effective long-term treatment has led to extensive gene therapy research focusing both on disease modifying as well as non-disease modifying aspects. Since genetic lesions are found in both familial as well as sporadic PD cases, the principle of introducing a normal gene to cure …

Don't Hate The Player, Hate The Game: Video Game Loot Boxes, Gambling, And A Call For Administrative Regulation, Jason Egielski

Hofstra Law Review

No abstract provided.

A Nutrient-Rich Traditional Insect For Improving Food Security And Reducing Biodiversity Loss In Madagascar And Sub-Saharan Africa, Cortni Borgerson, Brian L. Fisher, Be Noel Razafindrapaoly, Be Jean Rodolph Rasolofoniaina, Jeanne Mathilde Randriamanetsy, Be Lexion Razafindrapaoly, Delox Rajaona, Patsy Herrera, Joost Van Itterbeeck, Kenneth M. Martinez, Matthew L. Aardema

Department of Anthropology Faculty Scholarship and Creative Works

Forests, and the vertebrate species within them, are irreplaceable sources of food and nutrition for millions of people living in areas of high biodiversity. Unfortunately, many of these forests are being cleared for agriculture, and many animals are threatened with extinction from unsustainable hunting. Forest clearing and the hunting of threatened species are untenable solutions to long-term food insecurity and adequate nutrition, jeopardizing these species' survival, the healthy functioning of ecosystems, and the cultural identities of local people. Working with communities to develop culturally appropriate ways for people to obtain sustainable and legal sources of food from forests outside of …

Intravital Imaging Of Neocortical Heterotopia Reveals Aberrant Axonal Pathfinding And Myelination Around Ectopic Neurons, Alice M. Li, Robert A. Hill, Jaime Grutzendler

Dartmouth Scholarship

Neocortical heterotopia consist of ectopic neuronal clusters that are frequently found in individuals with cognitive disability and epilepsy. However, their pathogenesis remains poorly understood due in part to a lack of tractable animal models. We have developed an inducible model of focal cortical heterotopia that enables their precise spatiotemporal control and high-resolution optical imaging in live mice. Here, we report that heterotopia are associated with striking patterns of circumferentially projecting axons and increased myelination around neuronal clusters. Despite their aberrant axonal patterns, in vivo calcium imaging revealed that heterotopic neurons remain functionally connected to other brain regions, highlighting their potential …

The Pacific Sentinel: September 2021, Portland State University. Student Publications Board

The Pacific Sentinel

Editor: Vivian Veidt

Articles in this issue include:

• Letter From the Editor
• The Opaque Places of Cinema
• A “PIG” in Portland
• Jazzed to be Back
• Notes from Behind the Bar
• The Predicament of Mayor Wheeler
• The City of Portland Must Cut Ties With Israel

Airway Obstacle Course For Teaching Prehospital Providers Airway Techniques., Robert Young, John O Elliott, Brad D Gable

OhioHealth Research Institute Articles

BACKGROUND:  Early airway intervention is a vital step in the management of critically ill patients. Emergency medical service (EMS) providers are often first in the chain of survival with equipment to manage airway problems that arise. Therefore, it is paramount that they receive thorough training in aspects of airway management. Often, the training providers currently undergo does not reflect the environmental challenges inherent in EMS. Our obstacle course not only offers trainees a situational environment that simulates common challenges associated with the prehospital environment, but also provides a break from traditional tabletop and lecture-based training methods.

METHODS:  An airway obstacle …