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2021

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Summer Field Report, June-July 2021, W. Ross Silcock Sep 2021

Summer Field Report, June-July 2021, W. Ross Silcock

Nebraska Bird Review

Last summer my opening sentences were: “Overall, this was a fairly routine summer although birders in Nebraska know that ‘routine’ still holds promise of a few happenings out of the ordinary. The summer season primarily examines new breeding records, range expansions, and changes in numbers, up or down.” This summer was also rather routine but had its share of startling events. Foremost among these were only the second colony breeding of American White Pelicans, involving 1200 on nests; two, possibly the same, male Evening Grosbeaks in the southeast; record late by about a month Townsend’s Solitaire; two Lincoln’s Sparrows together …


Diminishing Returns: Results Of Black Rail Surveys In Nebraska, Joel G. Jorgensen, Lauren Greenwalt, Nancy E. Drilling, Caleb Strand, Stephen J. Brenner Sep 2021

Diminishing Returns: Results Of Black Rail Surveys In Nebraska, Joel G. Jorgensen, Lauren Greenwalt, Nancy E. Drilling, Caleb Strand, Stephen J. Brenner

Nebraska Bird Review

The uncertain status of the Black Rail in Nebraska is problematic. Different authors have interpreted existing reports differently resulting in varying conclusions about the species’ status. The exercise of deciphering the limited details of existing reports and litigating their credibility is of little value. The Black Rail is now a threatened species and there is almost no published information on whether it occurs regularly in Nebraska. Furthermore, the species has not been searched for in any consistent form or systematic manner. Without information and understanding about the species’ occurrence, taking actions to benefit and protect this species will undoubtedly be …


The Nebraska Bird Review, Volume 89 September 2021 Number 3 Sep 2021

The Nebraska Bird Review, Volume 89 September 2021 Number 3

Nebraska Bird Review

Summer Field Report, June - July 2021 by W. Ross Silcock 106

Diminishing Returns: Results of Black Rail Surveys in Nebraska by Joel G. Jorgensen, Lauren Greenwalt, Nancy E. Drilling, Caleb Strand and Stephen J. Brenner 128

A Brown-capped Black-capped Chickadee (Poecile atricapillus) in Sarpy County, Nebraska by W. Ross Silcock and Phil Swanson 136

2020 (32nd) Report of the NOU Records Committee by Mark A. Brogie 139

Black-throated Gray Warbler in Knox County, Nebraska by Mark A. Brogie 146

Subscription and Organization Information 147


New Ams Radiocarbon Ages From The Preceramic Levels Of Coxcatlan Cave, Puebla, Mexico: A Pleistocene Occupation Of The Tehuacan Valley?, Andrew D. Somerville, Isabel Casar, Joaquín Arroyo-Cabrales Sep 2021

New Ams Radiocarbon Ages From The Preceramic Levels Of Coxcatlan Cave, Puebla, Mexico: A Pleistocene Occupation Of The Tehuacan Valley?, Andrew D. Somerville, Isabel Casar, Joaquín Arroyo-Cabrales

KIP Articles

Archaeological studies at Coxcatlan Cave in the Tehuacan Valley of southern Puebla, Mexico, have been instrumental to the development of the chronology for the region and for our understanding of the origins of food production in the Americas. This article refines the Preceramic chronology of the Tehuacan Valley by presenting 14 new accelerated mass spectrometry (AMS) radiocarbon ages from faunal bone samples uncovered from early depositional levels of the rock shelter. Although bones associated with the El Riego (9893–7838 cal BP), Coxcatlan (7838–6375 cal BP), and Abejas (6375–4545 cal BP) phase zones of the cave yielded ages similar to those …


Climate Change And Vulnerability: Enhancing The Adaptive Capacity Of The Population Of Pakistan, G.M. Arif, Kiren Khan, Zeba Sathar Sep 2021

Climate Change And Vulnerability: Enhancing The Adaptive Capacity Of The Population Of Pakistan, G.M. Arif, Kiren Khan, Zeba Sathar

Climate and Environmental Changes

No abstract provided.


Cellular Activity Of Salmonella Typhimurium Artab Toxin And Its Receptor-Binding Subunit, Elise Overgaard, Brad Morris, Omid Mohammad Mousa, Adriana Rodriguez, Leyla Cufurovic, Richard S. Beard, Juliette K. Tinker Sep 2021

Cellular Activity Of Salmonella Typhimurium Artab Toxin And Its Receptor-Binding Subunit, Elise Overgaard, Brad Morris, Omid Mohammad Mousa, Adriana Rodriguez, Leyla Cufurovic, Richard S. Beard, Juliette K. Tinker

Biology Faculty Publications and Presentations

Salmonellosis is among the most reported foodborne illnesses in the United States. The Salmonella enterica Typhimurium DT104 phage type, which is associated with multidrug-resistant disease in humans and animals, possesses an ADP-ribosylating toxin called ArtAB. Full-length artAB has been found on a number of broad-host-range non-typhoidal Salmonella species and serovars. ArtAB is also homologous to many AB5 toxins from diverse Gram-negative pathogens, including cholera toxin (CT) and pertussis toxin (PT), and may be involved in Salmonella pathogenesis, however, in vitro cellular toxicity of ArtAB has not been characterized. artAB was cloned into E. coli and initially isolated …


(Re)Proposal Of Three Cambrian Subsystems And Their Geochronology, Ed Landing, Gerd Geyer, Mark D. Schmitz, Thomas Wotte, Artem Kouchinsky Sep 2021

(Re)Proposal Of Three Cambrian Subsystems And Their Geochronology, Ed Landing, Gerd Geyer, Mark D. Schmitz, Thomas Wotte, Artem Kouchinsky

Geosciences Faculty Publications and Presentations

The Cambrian is anomalous among geological systems as many reports divide it into three divisions of indeterminate rank. This use of “lower”, “middle”, and “upper” has been a convenient way to subdivide the Cambrian despite agreement it consists of four global series. Traditional divisions of the system into regional series (Lower, Middle, Upper) reflected local biotic developments not interprovincially correlatable with any precision. However, use of “lower”, “middle”, and “upper” is unsatisfactory. These adjectives lack standard definition, evoke the regional series, and are misused. Notably, there is an almost 50 year use of three Cambrian subsystems and a 1997 proposal …


An Extended Essay On Church Autonomy, Carl H. Esbeck Sep 2021

An Extended Essay On Church Autonomy, Carl H. Esbeck

Faculty Publications

The doctrine of church autonomy has its own exclusive line of precedent running from Watson v. Jones (1872) through Kedroff v. St. Nicholas Cathedral (1952) - where the doctrine was first recognized as having First Amendment stature - and culminating with renewed vigor for religious institutional autonomy in the unanimous decision of Hosanna-Tabor Evangelical Lutheran Church and School v. EEOC (2012). Attention to church autonomy has expanded rapidly since the Supreme Court’s decision in Hosanna-Tabor, and its scope is much disputed as it pushes aside other claims and interests. In its most familiar form—the “ministerial exception” - it is …


Critical Dialogue And Regulation: Learning From Engineering Mistakes, Robert Eli Rosen Sep 2021

Critical Dialogue And Regulation: Learning From Engineering Mistakes, Robert Eli Rosen

Transportation Law Journal

Effective regulation requires knowledge. New forms of regulation, sometimes called "co-regulation," propose promoting learning and continual improvement in the regulated. In particular, inducing experimentalism has been named as a regulator's task.

This Article argues that regulators also need to become adept in critical dialogue. In the regulatory process, the critique of the rationality of extant techniques and practices can be an engine to advance public interests. Such critical thinking is attentive to false objectifications and the limitations of truth-claims. The examples in this Article demonstrate that regulatory goals can be advanced when regulators induce critical thinking. Both the regulated and …


Ce 611 Syllabus: Development Over The Lifespan, Mary Fawcett Sep 2021

Ce 611 Syllabus: Development Over The Lifespan, Mary Fawcett

Counselor Education Syllabi

The purpose of this course is to promote students’ thinking and learning about human growth, adaptation, and change throughout the lifespan. Major theories, issues, eras, and trends in human development will be addressed.


Seasonal Feeding And Movement Responses Of Resident Sculpin In The Canadian Arctic, Nathan Thomas Hermann Sep 2021

Seasonal Feeding And Movement Responses Of Resident Sculpin In The Canadian Arctic, Nathan Thomas Hermann

Master's Theses and Capstones

Environments change across space and time, requiring organisms to adapt behaviorally and/or physiologically. In the Arctic, where productivity varies greatly among seasons, many marine species exploit a resource pulse associated with annual ice melt. Melting sea-ice releases zooplankton on and within the ice into open water causing many consumers to migrate with the receding ice; however, resident species may too rely on the ephemeral prey source. Fourhorn Sculpin (Myoxocephalus quadricornis) and Slimy Sculpin (Cottus cognatus) are residents of Tremblay Sound, Nunavut Canada which is known as a seasonally productive system in the Arctic. I characterized the seasonal behavior of sculpin …


Csd 320.01: Phonological Development & Phonetics, Amy M. Glaspey Sep 2021

Csd 320.01: Phonological Development & Phonetics, Amy M. Glaspey

University of Montana Course Syllabi, 2021-2025

No abstract provided.


Wild 346.01: Wildlife Physiological Ecology, Creagh W. Breuner Sep 2021

Wild 346.01: Wildlife Physiological Ecology, Creagh W. Breuner

University of Montana Course Syllabi, 2021-2025

No abstract provided.


Wild 105n.01: Wildlife And People, Erim Gomez Sep 2021

Wild 105n.01: Wildlife And People, Erim Gomez

University of Montana Course Syllabi, 2021-2025

No abstract provided.


Evaluation Of In-Cab Air Quality For Nonroad Diesel Construction Equipment, Phil Lewis, Sherif El Khouly, Adam Mayer, Jeremy Johnson Sep 2021

Evaluation Of In-Cab Air Quality For Nonroad Diesel Construction Equipment, Phil Lewis, Sherif El Khouly, Adam Mayer, Jeremy Johnson

The Professional Constructor

Previous research indicates that air quality near the cabs of nonroad diesel equipment may exceed recommended exposure limits for certain pollutants. The objective of this case study was to collect and analyze air pollutant data near the cabs of nonroad diesel equipment while performing real world activities. Using state-of-the-art instrumentation, the research team conducted 24 tests on nine different items of nonroad equipment. The team collected data related to pollutant concentrations of carbon monoxide, carbon dioxide, nitric oxide, nitrogen dioxide, particulate matter, and black carbon. Average concentrations of carbon monoxide and nitric oxide did not exceed published exposure limits on …


Understanding And Avoiding Ai Failures: A Practical Guide, Robert Williams, Roman Yampolskiy Sep 2021

Understanding And Avoiding Ai Failures: A Practical Guide, Robert Williams, Roman Yampolskiy

Faculty and Staff Scholarship

As AI technologies increase in capability and ubiquity, AI accidents are becoming more common. Based on normal accident theory, high reliability theory, and open systems theory, we create a framework for understanding the risks associated with AI applications. This framework is designed to direct attention to pertinent system properties without requiring unwieldy amounts of accuracy. In addition, we also use AI safety principles to quantify the unique risks of increased intelligence and human-like qualities in AI. Together, these two fields give a more complete picture of the risks of contemporary AI. By focusing on system properties near accidents instead of …


Differential Effects Of Polyphenols On Insulin Proteolysis By The Insulin-Degrading Enzyme, Qiuchen Zheng, Micheal T. Kebede, Bethany Lee, Claire A. Krasinski, Saadman Islam, Liliana A. Wurfl, Merc M. Kemeh, Valerie A. Ivancic, Charles E. Jakobsche, Donald E. Spratt, Noel Lazo Sep 2021

Differential Effects Of Polyphenols On Insulin Proteolysis By The Insulin-Degrading Enzyme, Qiuchen Zheng, Micheal T. Kebede, Bethany Lee, Claire A. Krasinski, Saadman Islam, Liliana A. Wurfl, Merc M. Kemeh, Valerie A. Ivancic, Charles E. Jakobsche, Donald E. Spratt, Noel Lazo

Chemistry

The insulin-degrading enzyme (IDE) possesses a strong ability to degrade insulin and Aβ42 that has been linked to the neurodegeneration in Alzheimer’s disease (AD). Given this, an attractive IDE-centric strategy for the development of therapeutics for AD is to boost IDE’s activity for the clearance of Aβ42 without offsetting insulin proteostasis. Recently, we showed that resveratrol enhances IDE’s activity toward Aβ42. In this work, we used a combination of chromatographic and spectroscopic techniques to investigate the effects of resveratrol on IDE’s activity toward insulin. For comparison, we also studied epigallocatechin-3-gallate (EGCG). Our results show that the two polyphenols affect the …


Blackness And Existential Crimes In The Modern Racial State, Natalie P. Byfield Sep 2021

Blackness And Existential Crimes In The Modern Racial State, Natalie P. Byfield

Connecticut Law Review

This Essay presents the concept of “existential crime.” It argues that our notion of crime has conflated acts that challenge the racial premise on which a state is founded with acts that breach what Karim Murji (2009) calls “norms of propriety.”1 It argues that the conflation of these different types of social acts into our conceptualization of crime is a problem because this unnecessary and deliberate synthesis (1) privileges Western liberal philosophies that presume justice for everyone is achievable in states that were originally built on criteria for racial inclusion/exclusion, e.g., racial domination of one group over others; and (2) …


The Link Between Diabetes Mellitus And Tau Hyperphosphorylation: Implications For Risk Of Alzheimer's Disease, Amy L. Hobday, Mayur S. Parmar Sep 2021

The Link Between Diabetes Mellitus And Tau Hyperphosphorylation: Implications For Risk Of Alzheimer's Disease, Amy L. Hobday, Mayur S. Parmar

HPD Articles

Diabetes mellitus (DM) is characterized by hyperglycemia caused by a lack of insulin, insulin resistance, or both. It is associated with the development of secondary complications resulting in several comorbidities. Recent studies have revealed an increased risk of developing cognitive dysfunction or dementia in diabetes patients. Diabetes mellitus is considered a risk factor for many neurodegenerative diseases, including Alzheimer's disease (AD). There is increasing evidence to support a link between DM and AD. Studies have shown the dysfunction of insulin signaling in the brain, resulting in increased tau protein phosphorylation (hyperphosphorylation), a hallmark and biomarker of AD pathology, leading to …


Kentucky Traffic Collision Facts 2020, Eric Green, Paul Ross, Christopher Blackden, Michael Fields, Kenneth Agent Sep 2021

Kentucky Traffic Collision Facts 2020, Eric Green, Paul Ross, Christopher Blackden, Michael Fields, Kenneth Agent

Kentucky Transportation Center Research Report

KENTUCKY’S TRAFFIC COLLISION FACTS report is based on collision reports submitted to the Kentucky State Police Records Branch. As required by Kentucky Revised Statutes 189.635:

“Every law enforcement agency whose officers investigate a vehicle accident of which a report must be made...shall file a report of the accident...within ten days after investigation of the accident upon forms supplied by the bureau.”

The stated purpose of this requirement is to utilize data on traffic collisions for such purposes as will improve the traffic safety program in the Commonwealth.


Tapping Into Food Industry: A Comparative Dual-Model Study Of Religion And Culture On Food Products’ Purchase Intention, Sumera Syed, Fauziah S. Ahmad, Syed R. H. Shah Sep 2021

Tapping Into Food Industry: A Comparative Dual-Model Study Of Religion And Culture On Food Products’ Purchase Intention, Sumera Syed, Fauziah S. Ahmad, Syed R. H. Shah

Journal of Mediterranean Tourism Research

Due to increased trend of globalization and immigration to advanced countries during the past decade, Halal food consumers are being observed not only in Islamic countries but also in Western European countries. Moreover, the concepts of hygiene, quality and cleanliness, being often related to Halal food, make it equally favorable for consumption to non-Muslims. However, this vast area of Halal food sector still needs further exploration. Though recent studies have, to some extent, tried to explore the impact of religiosity on Halal food purchase intention, but still the impact of religion on Halal food purchase intention remains unexplored. Moreover, almost …


Covid-19 Pandemic On Youth Tourism, Kübra Asan Sep 2021

Covid-19 Pandemic On Youth Tourism, Kübra Asan

Journal of Mediterranean Tourism Research

The COVID-19 pandemic, which affected the entire world, has profoundly affected the tourism sector based on human mobility. However, it is estimated that the effects of the pandemic will be less in youth tourism. The study aims to explain the effects of the pandemic on the youth tourism market. In this context, a survey study was conducted in the InterRail Turkey Community/Unirail Group. The data collected by using the online survey technique were subjected to principal component analeymiş. After the analysis, it was seen that the effects of the pandemic on the tourism behavior of the participants can be explained …


Motherism, African Women And Ecological Advocacy In Aminata Sow Fall’S L’Ex-Père De La Nation And Douceurs Du Bercail, Olubunmi O. Ashaolu Sep 2021

Motherism, African Women And Ecological Advocacy In Aminata Sow Fall’S L’Ex-Père De La Nation And Douceurs Du Bercail, Olubunmi O. Ashaolu

The Goose

The literary discourse of francophone Africa, has been indicted for ecocritical passivity. Yet many literary texts emanating from francophone Africa are replete with portraits of the environment. Even though Aminata Sow Fall, the Senegalese socio-realist falls within the category of authors who seek equilibrium in their treatment of African postcolonial issues, most of her works are laden with ecocritical concerns. Hidden within the literary portraits of postcolonial and environmental chaos of Africa lies Sow Fall’s projection of African problems and their alternative solution via her characters’ sensitization of ecological consciousness in readers. Through the theoretical framework of Catherine O. Acholonu’s …


The Effects And Mechanisms Of Phytochemicals On Alzheimer’S Disease Neuropathology, David Ross Sep 2021

The Effects And Mechanisms Of Phytochemicals On Alzheimer’S Disease Neuropathology, David Ross

Loma Linda University Electronic Theses, Dissertations & Projects

Alzheimer’s disease effects millions of people, yet pharmacological treatments are limited. In the absence of effective treatments, identifying factors that can decrease the risk of developing Alzheimer’s disease is of significant interest. A growing body of epidemiological and experimental evidence suggests that dietary fruits and vegetables can have neuroprotective effects against the harmful effects of oxidative stress, neuroinflammation, and aging. These effects are mediated by various phytochemicals, which are compounds found in plants that can possess antioxidant, anti-inflammatory, and other beneficial properties. This review addresses epidemiological and experimental evidence for the effects and potential mechanisms of several commonly consumed phytochemicals …


Women's Age Of First Exposure To Internet Pornography Predicts Sexual Victimization, Sarah J. Harsey, Laura K. Noll, Melissa J. Miller, Ryan A. Shallcross Sep 2021

Women's Age Of First Exposure To Internet Pornography Predicts Sexual Victimization, Sarah J. Harsey, Laura K. Noll, Melissa J. Miller, Ryan A. Shallcross

Dignity: A Journal of Analysis of Exploitation and Violence

Increases in the availability and accessibility of Internet pornography have led growing numbers of children to become consumers of sexually explicit media. Research has identified negative behavioral and attitudinal outcomes associated with Internet pornography use in childhood and adolescence, but few studies have examined sexual victimization as a correlate. The current study aimed to examine the association between age of first Internet pornography exposure and sexual victimization. Data from 154 undergraduate women yielded several important findings. Women who viewed Internet pornography unintentionally at a younger age reported more sexual victimization. Specifically, compared to women who were first unintentionally exposed to …


“My Daughter Was Sacrificed By My Mother”: Women’S Involvement In Ritually Motivated Violence And Murder In Contemporary Africa, Chima Agazue Sep 2021

“My Daughter Was Sacrificed By My Mother”: Women’S Involvement In Ritually Motivated Violence And Murder In Contemporary Africa, Chima Agazue

Dignity: A Journal of Analysis of Exploitation and Violence

Ritually motivated crimes are grave crimes that continue to plague contemporary Africa. Occasionally, victims abducted for ritual purposes are discovered and set free. Fresh or decomposing bodies are spotted somewhere, often with missing parts taken by the ritual killers who killed the victims. Some missing persons in the continent are presumed to have been abducted or killed by ritually motivated criminals. Although ritually motivated crimes take different forms, most of them involve brutal acts of violence and murder. The barbaric manner in which these criminals attack or slaughter their victims creates fear and panic. Traditionally, men commit serious crimes involving …


Alzheimer's Disease Alters Oligodendrocytic Glycolytic And Ketolytic Gene Expression, Erin R Saito, Justin B Miller, Oscar Harari, Carlos Cruchaga, Kathie A Mihindukulasuriya, John S K Kauwe, Benjamin T Bikman Sep 2021

Alzheimer's Disease Alters Oligodendrocytic Glycolytic And Ketolytic Gene Expression, Erin R Saito, Justin B Miller, Oscar Harari, Carlos Cruchaga, Kathie A Mihindukulasuriya, John S K Kauwe, Benjamin T Bikman

2020-Current year OA Pubs

INTRODUCTION: Sporadic Alzheimer's disease (AD) is strongly correlated with impaired brain glucose metabolism, which may affect AD onset and progression. Ketolysis has been suggested as an alternative pathway to fuel the brain.

METHODS: RNA-seq profiles of post mortem AD brains were used to determine whether dysfunctional AD brain metabolism can be determined by impairments in glycolytic and ketolytic gene expression. Data were obtained from the Knight Alzheimer's Disease Research Center (62 cases; 13 controls), Mount Sinai Brain Bank (110 cases; 44 controls), and the Mayo Clinic Brain Bank (80 cases; 76 controls), and were normalized to cell type: astrocytes, microglia, …


Amygdala Functional Connectivity And Negative Reactive Temperament At Age 4 Months, Courtney A. Filippi, Sanjana Ravi, Maya Bracy, Anderson M. Winkler, Chad Sylvester, Daniel Samuel Pine, Nathan A. Fox Sep 2021

Amygdala Functional Connectivity And Negative Reactive Temperament At Age 4 Months, Courtney A. Filippi, Sanjana Ravi, Maya Bracy, Anderson M. Winkler, Chad Sylvester, Daniel Samuel Pine, Nathan A. Fox

School of Medicine Publications

Objective

Infant amygdalaconnectivity correlates with maternal reports of infant temperament characterized by novelty-evoked distress and avoidance. However, no studies have examined how human infant amygdala connectivity relates to direct observations of novelty-evoked distress. This study examined the link between amygdala connectivity and infant novelty-evoked distress using direct observation of temperament.

Method

Novelty-evoked distress was assessed at 4 months of age (N = 90) using a standardized reactivity assessment and parent report. Within 3 weeks of assessment, resting-state functional magnetic resonance imaging was collected in a subset of infants (n = 34). Using a whole-brain voxelwise approach, amygdala connectivity associated …


Effectiveness And Safety Of Oral Anticoagulants Among Nonvalvular Atrial Fibrillation Patients With Active Cancer, Steve Deitelzweig, Allison V. Keshishian, Yan Zhang, Amiee Kang, Amol D. Dhamane, Xuemei Luo, Christian Klem, Mauricio Ferri, Jenny Jiang, Huseyin Yuce, Gregory Y.H. Lip Sep 2021

Effectiveness And Safety Of Oral Anticoagulants Among Nonvalvular Atrial Fibrillation Patients With Active Cancer, Steve Deitelzweig, Allison V. Keshishian, Yan Zhang, Amiee Kang, Amol D. Dhamane, Xuemei Luo, Christian Klem, Mauricio Ferri, Jenny Jiang, Huseyin Yuce, Gregory Y.H. Lip

Publications and Research

BACKGROUND Patients with cancer are more likely to develop nonvalvular atrial fibrillation (NVAF). Currently there are no definitive clinical trials or treatment guidelines for NVAF patients with concurrent cancer.

OBJECTIVES This subgroup analysis of the ARISTOPHANES study compared the risk of stroke/systemic embolism (stroke/SE) and major bleeding (MB) among NVAF patients with active cancer who were prescribed non–vitamin K antagonist oral anticoagulants (NOACs) or warfarin.

METHODS A retrospective observational study was conducted in NVAF patients with active cancer who newly initiated apixaban, dabigatran, rivaroxaban, or warfarin from January 1, 2013, through September 30, 2015, with the use of Medicare and …


Bioactive In Situ Crosslinkable Polymer-Peptide Hydrogel For Cell Delivery To The Intervertebral Disc In A Rat Model, Marcos N Barcellona, Julie E Speer, Liufang Jing, Deepanjali S Patil, Munish C Gupta, Jacob M Buchowski, Lori A Setton Sep 2021

Bioactive In Situ Crosslinkable Polymer-Peptide Hydrogel For Cell Delivery To The Intervertebral Disc In A Rat Model, Marcos N Barcellona, Julie E Speer, Liufang Jing, Deepanjali S Patil, Munish C Gupta, Jacob M Buchowski, Lori A Setton

2020-Current year OA Pubs

Degeneration of the intervertebral disc (IVD) is associated with significant biochemical and morphological changes that include a loss of disc height, decreased water content and decreased cellularity. Cell delivery has been widely explored as a strategy to supplement the nucleus pulposus (NP) region of the degenerated IVD in both pre-clinical and clinical trials, using progenitor or primary cell sources. We previously demonstrated an ability for a polymer-peptide hydrogel, serving as a culture substrate, to promote adult NP cells to undergo a shift from a degenerative fibroblast-like state to a juvenile-like NP phenotype. In the current study, we evaluate the ability …