Digital Commons Network^™

Biom 427.01: General Parasitology, James David Driver

University of Montana Course Syllabi

No abstract provided.

Artz 105a.02: Visual Language - Drawing, Karl Yonner Schwiesow

University of Montana Course Syllabi

No abstract provided.

Bioo 475.04: Mammalogy Lab, Jedediah Farrell Brodie, Angela Hornsby

University of Montana Course Syllabi

No abstract provided.

Biol 338-001: Ecology Of Dining Hall, Maria Stanko

Biology Syllabi

No abstract provided.

Sts 221-451: Introduction To Sociology, Maria Paradiso

Humanities Syllabi

No abstract provided.

Sts 221-453: Introduction To Sociology, Maria Paradiso

Humanities Syllabi

No abstract provided.

Sts 360-451: Ethics And The Environment, Adam See

Humanities Syllabi

No abstract provided.

Sts 360-453: Ethics And The Environment, Adam See

Humanities Syllabi

No abstract provided.

Phil 337-451: World Religions, Charles Brooks

Humanities Syllabi

No abstract provided.

Phil 337-453: World Religions, Charles Brooks

Humanities Syllabi

No abstract provided.

Phil 334-005: Engineering Ethics, Adam See

Humanities Syllabi

No abstract provided.

Phil 334-457: Engineering Ethics, Amber George

Humanities Syllabi

No abstract provided.

Phil 334-459: Engineering Ethics, Amber George

Humanities Syllabi

No abstract provided.

Eng 340-H01: Oral Presentation, Carol Johnson

Humanities Syllabi

No abstract provided.

Eng 340-H03: Oral Presentation, Carol Johnson

Humanities Syllabi

No abstract provided.

Can Fingernail Quality Predict Bone Damage In Type 2 Diabetes Mellitus? A Pilot Study, Praveer Sihota, Rimesh Pal, Ram N. Yadav, Deepak Neradi, Shailesh Karn, Vijay G. Goni, Siddhartha Sharma, Vishwajeet Mehandia, Sanjay Kumar Bhadada, Navin Kumar, Sudhaker D. Rao

Endocrinology Articles

Type 2 diabetes mellitus (T2DM) adversely affects the normal functioning, intrinsic material properties, and structural integrity of many tissues, including bone. It is well known that the clinical utility of areal bone mineral density (aBMD) is limited to assess bone strength in individuals with T2DM. Therefore, there is a need to explore new diagnostic techniques that can better assist and improve the accuracy of assessment of bone tissue quality. The present study investigated the link between bone and fingernail material/compositional properties in type 2 diabetes mellitus (T2DM). For that, femoral head and fingernail samples were obtained from twenty-five adult female …

Integration Of Crop-Livestock Systems: An Opportunity To Protect Grasslands From Conversion To Cropland In The Us Great Plains, Alexander J. Smart, Daren Redfearn, Robert Mitchell, Tong Wang, Cody Zilverberg, Peter J. Bauman, Justin D. Derner, Julie Walker, Cody Wright

Native Plant Focused Publications

The Great Plains is a mixture of cropland and grassland mainly used for agricultural purposes, with grasslands under continual threat of conversion to cropland. Agriculturists are advocating for the integration of crop-livestock systems (ICLS) to recouple nutrient cycles, improve biodiversity, and increase resilience of agricultural operations. We address the benefits of ICLS in the Great Plains, contending that focus on improving soil health and financial stability of agricultural operations should reduce the conversion of grasslands to cropland. Using US Department of Agriculture National Agricultural Statistics Service Census of Agriculture survey data from the 1925−2017 category “cropland used only for pasture …

Digital Sustainability And Entrepreneurship: How Digital Innovations Are Helping Tackle Climate Change And Sustainable Development, Gerard George, Ryan K. Merrill, Simon J. D. Schillebeeckx

Research Collection Lee Kong Chian School Of Business

We explore how digital technologies are helping address grand challenges to tackle climate change and promote sustainable development. With digital technologies, entrepreneurial organizations have adopted innovative approaches to tackle seemingly intractable societal challenges. We refer to these broadly as digital sustainability activities. By focusing on the digital toolbox employed by pioneering organizations, we propose a research agenda that generates novel questions for entrepreneurship, business models, and ecosystems as well as new ways of thinking about trust and institutional logics. We believe that digital sustainability can spur empirical advances in entrepreneurship, innovation, and strategy with potential for positive impact on society.

Tyranny Of The Task Force: Police Abolition And The Counterinsurgent Campus, Dylan Rodríguez

Connecticut Law Review

No abstract provided.

Keeping Nutrient Pollution At Bay: An Analysis Of Efforts To Mitigate Non-Point Source Pollution In The Chesapeake Bay, Madison Hinkle

West Virginia Law Review

The Chesapeake Bay is one of the most important estuaries in the United States, adding to the region’s ecological, economic, recreational, historic, and cultural value. In 1982, a study was conducted that determined that a rapid loss of aquatic life in the Bay was due to nutrient pollution, specifically nitrogen and phosphorus, the majority of which is associated with the agricultural industry. A number of the jurisdictions2 within the Bay Watershed established the first Chesapeake Bay Agreement in 1983, aimed at abating the issues. Over the next four decades, the Agreement was then modified and resigned, additional jurisdictions have signed …

Aurora Kinase A Inhibition Reverses The Warburg Effect And Elicits Unique Metabolic Vulnerabilities In Glioblastoma, Trang T. T. Nguyen, Enyuan Shang, Chang Shu, Sungsoo Kim, Angeliki Mela, Nelson Humala, Aayushi Mahajan, Hee Won Yang, Hasan Orhan Akman, Catarina M. Quinzii, Guoan Zhang, Mike-Andrew Westhoff, Georg Karpel-Massler, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin

Publications and Research

Aurora kinase A (AURKA) has emerged as a drug target for glioblastoma (GBM). However, resistance to therapy remains a critical issue. By integration of transcriptome, chromatin immunoprecipitation sequencing (CHIP-seq), Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq), proteomic and metabolite screening followed by carbon tracing and extracellular flux analyses we show that genetic and pharmacological AURKA inhibition elicits metabolic reprogramming mediated by inhibition of MYC targets and concomitant activation of Peroxisome Proliferator Activated Receptor Alpha (PPARA) signaling. While glycolysis is suppressed by AURKA inhibition, we note an increase in the oxygen consumption rate fueled by enhanced fatty acid oxidation (FAO), which was …

Antimicrobial Resistance: Is Health Technology Assessment Part Of The Solution Or Part Of The Problem?, Abigail Colson, Alec Morton, Christine Årdal, Kalipso Chalkidou, Sally Davies, Louis Garrison, Mark Jit, Ramanan Laxminarayan, Itamar Megiddo, Chantal Morel, Justice Nonvignon, Kevin Outterson, John Rex, Abdur Razzaque Sarker, Mark Sculpher, Beth Woods, Yue Xiao

Faculty Scholarship

Antimicrobial resistance is a serious challenge to the success and sustainability of our healthcare systems. There has been increasing policy attention given to antimicrobial resistance in the last few years, and increased amounts of funding have been channeled into funding for research and development of antimicrobial agents. Nevertheless, manufacturers doubt whether there will be a market for new antimicrobial technologies sufficient to enable them to recoup their investment. Health technology assessment (HTA) has a critical role in creating confidence that if valuable technologies can be developed they will be reimbursed at a level that captures their true value. We identify …

Selective Serotonin Reuptake Inhibitors And Adverse Effects: A Narrative Review, Amber N. Edinoff, Haseeb A. Akuly, Tony A. Hanna, Carolina O. Ochoa, Shelby J. Patti, Yahya A. Ghaffar, Alan David Kaye, Omar Viswanath, Ivan Urits, Andrea G. Boyer, Elyse M. Cornett, Adam M. Kaye

School of Pharmacy Faculty Articles

Depression is the most prevalent psychiatric disorder in the world, affecting 4.4% of the global population. Despite an array of treatment modalities, depressive disorders remain difficult to manage due to many factors. Beginning with the introduction of fluoxetine to the United States in 1988, selective serotonin reuptake inhibitors (SSRIs) quickly became a mainstay of treatment for a variety of psychiatric disorders. The primary mechanism of action of SSRIs is to inhibit presynaptic reuptake of serotonin at the serotonin transporter, subsequently increasing serotonin at the postsynaptic membrane in the serotonergic synapse. The six major SSRIs that are marketed in the USA …

Mechanically Transduced Immunosorbent Assay To Measure Protein-Protein Interactions, Christopher J. Petell, Kathyrn Randene, Michael Pappas, Diego Sandoval, Brian Dstrahl, Joseph S. Harrison, Joshua P. Steimel

College of the Pacific Faculty Articles

Measuring protein-protein interaction (PPI) affinities is fundamental to biochemistry. Yet, conventional methods rely upon the law of mass action and cannot measure many PPIs due to a scarcity of reagents and limitations in the measurable affinity ranges. Here, we present a novel technique that leverages the fundamental concept of friction to produce a mechanical signal that correlates to binding potential. The mechanically transduced immunosorbent (METRIS) assay utilizes rolling magnetic probes to measure PPI interaction affinities. METRIS measures the translational displacement of protein-coated particles on a protein-functionalized substrate. The translational displacement scales with the effective friction induced by a PPI, thus …

Castor Canadensis Fall 2021, Jedediah Smith Society

Castor Canadensis - Jedediah Smith Society

Newsletter of the Jedediah Smith Society

Season Of Prescribed Fire Determines Grassland Restoration Outcomes After Fire Exclusion And Overgrazing, Erin N. Novak, Michelle Bertelsen, Dick Davis, Devin M. Grobert, Kelly G. Lyons, Jason P. Martina, W. Matt Mccaw, Matthew O'Toole, Joseph W. Veldman

Biology Faculty Research

Fire exclusion and mismanaged grazing are globally important drivers of environmental change in mesic C₄ grasslands and savannas. Although interest is growing in prescribed fire for grassland restoration, we have little long-term experimental evidence of the influence of burn season on the recovery of herbaceous plant communities, encroachment by trees and shrubs, and invasion by exotic grasses. We conducted a prescribed fire experiment (seven burns between 2001 and 2019) in historically fire-excluded and overgrazed grasslands of central Texas. Sites were assigned to one of four experimental treatments: summer burns (warm season, lightning season), fall burns (early cool season), winter …

The Goose Picks: Race, Colonization, And Environment, Anita Girvan, Julien Defraeye, Alec Follett, David Huebert, Jordan Kinder, Rina Garcia Chua, Siobhan Angus

The Goose

Reading recommendations by The Goose team on race, colonization, and the environment.

In Situ Imaging Of Bacterial Outer Membrane Projections And Associated Protein Complexes Using Electron Cryo-Tomography, Mohammed Kaplan, Georges Chreifi, Lauren Ann Metskas, Janine Liedtke, Cecily R. Wood, Catherine M. Oikonomou, William J. Nicolas, Poorna Subramanian, Lori A. Zacharoff, Yuhang Wang, Yi-Wei Chang, Morgan Beeby, Megan J. Dobro, Yongtao Zhu, Mark J. Mcbride, Ariane Briegel, Carrie L. Shaffer, Grant J. Jensen

Veterinary Science Faculty Publications

The ability to produce outer membrane projections in the form of tubular membrane extensions (MEs) and membrane vesicles (MVs) is a widespread phenomenon among diderm bacteria. Despite this, our knowledge of the ultrastructure of these extensions and their associated protein complexes remains limited. Here, we surveyed the ultrastructure and formation of MEs and MVs, and their associated protein complexes, in tens of thousands of electron cryo-tomograms of ~90 bacterial species that we have collected for various projects over the past 15 years (Jensen lab database), in addition to data generated in the Briegel lab. We identified outer MEs and MVs …

2021-September-01-Gray Fossil Site Volunteers Can Help Uncover The Ancient Past, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY, Tenn. – Individuals who would like to join East Tennessee State University’s world-class team of paleontologists exploring the ancient history of East Tennessee are invited to volunteer this fall at the Gray Fossil Site and Museum.

Volunteers needed!

At top: Wet screening takes place on the grounds of the Gray Fossil Site, behind the museum. This essential process has relied on volunteer help for …

2020 (32nd) Report Of The Nou Records Committee, Mark A. Brogie

Nebraska Bird Review

ebraska: 2017” (NOURC 2017).

Nebraska State List: The following includes all revisions made by the American Ornithological Society (Chesser et al. 2020) in 2020 including scientific name changes and taxonomic realignment that affect the current published “Official List of the Birds of Nebraska: 2017” (NOURC 2017, wwwNOUbirds.org). This report includes all accounts submitted during the 2020 calendar year covering 29 records with accession numbers 2258 – 2286.

2020 Additions/Deletions to the “Official List of the Birds of Nebraska”: Two new species were added in 2020.: Black Phoebe (Sayornis nigricans) 1. A single bird was photographed (Class 1-P, TL) 26 April …