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The Saga Of The Notre Dame Law School Class Of 1969 “Fierce Competition, Stronger Friendships”, Notre Dame Law School, Class Of 1969, Jim Starshak, Joe Kennedy

About the Law School

The Saga is a collective memorial of the Notre Dame Law School class of 1969 of their time spent at the law school.

Front Matter

• Memorial Names
• Introductory Note
• The First of the Fighting Irish

Introduction
Before the Beginning
In the Beginning

• Our Class
• Orientation with Dean O'Meara

First Semester

• Football
• Preliminary Matters
• Courses
• Miscellaneous Matters
• Social Activities
• Lunch with Dean O'Meara
• Food

Second Semester

• Courses
• Lunch with Dean O'Meara
• Cartels and Comprehensive Exams
• Social Activities
• Summer Recess

Third Semester

• Courses
• Social Activities

Fourth Semester

• Courses
• Social Activities
• Dean Joseph O'Meara's Retirement
• Robert F. Kennedy at Notre Dame
• MLK Candlelight …

Evaluating Otter Reintroduction Outcomes Using Genetic Spatial Capture-Recapture Modified For Dendritic Networks, Sean M. Murphy, Jennifer R. Adams, Lisette P. Waits, John J. Cox

Forestry and Natural Resources Faculty Publications

Monitoring the demographics and genetics of reintroduced populations is critical to evaluating reintroduction success, but species ecology and the landscapes that they inhabit often present challenges for accurate assessments. If suitable habitats are restricted to hierarchical dendritic networks, such as river systems, animal movements are typically constrained and may violate assumptions of methods commonly used to estimate demographic parameters. Using genetic detection data collected via fecal sampling at latrines, we demonstrate applicability of the spatial capture–recapture (SCR) network distance function for estimating the size and density of a recently reintroduced North American river otter (Lontra canadensis) population in …

Novel Insights Into Negative Pressure Wound Healing From An In Situ Porcine Perspective, Jacob G. Hodge, Ashley L. Pistorio, Christopher A. Neal, Hongyan Dai, Jennifer G. Nelson-Brantley, Molly E. Steed, Richard A. Korentager, David S. Zamierowski, Adam J. Mellott

School of Medicine Faculty Research

Negative pressure wound therapy (NPWT) is used clinically to promote tissue formation and wound closure. In this study, a porcine wound model was used to further investigate the mechanisms as to how NPWT modulates wound healing via utilization of a form of NPWT called the vacuum-assisted closure. To observe the effect of NPWT more accurately, non-NPWT control wounds containing GranuFoam™ dressings, without vacuum exposure, were utilized. In situ histological analysis revealed that NPWT enhanced plasma protein adsorption throughout the GranuFoam™, resulting in increased cellular colonization and tissue ingrowth. Gram staining revealed that NPWT decreased bacterial dissemination to adjacent tissue with …

Terrestrial Snails And Slugs Of Nevada, Usa: An Overview Of Taxa, Biogeography, And Habitat Affinities, Mark A. Ports

Western North American Naturalist

The biogeography and habitat affinities of the Recent taxa of terrestrial mollusks of Nevada, western USA, are discussed herein. A total of 52 land snails and slug species were found in Nevada, of which 21 are newly reported records. Two native land snails found previously were not found by this author, and 6 additional species are possible for the state. Of the 47 species of land snail found in the state, 42 are considered native, while 5 are introduced. Only one slug, Deroceras laeve, is considered native, while 4 others are introduced. Land mollusks in eastern and central Nevada …

Recent Applications Of Quantitative Systems Pharmacology And Machine Learning Models Across Diseases, Sara Sadat Aghamiri1, Rada Amin, Tomáš Helikar

Department of Biochemistry: Faculty Publications

Quantitative systems pharmacology (QSP) is a quantitative and mechanistic platform describing the phenotypic interaction between drugs, biological networks, and disease conditions to predict optimal therapeutic response. In this meta-analysis study, we review the utility of the QSP platform in drug development and therapeutic strategies based on recent publications (2019–2021). We gathered recent original QSP models and described the diversity of their applications based on therapeutic areas, methodologies, software platforms, and functionalities. The collection and investigation of these publications can assist in providing a repository of recent QSP studies to facilitate the discovery and further reusability of QSP models. Our review …

Assemblages Of Acari In Shallow Burials: Mites As Markers Of The Burial Environment, Of The Stage Of Decay And Of Body‑Cadaver Regions, Jas K. Rai, Brian J. Pickles, M. Alejandra Perotti

Harold W. Manter Laboratory of Parasitology: Library Materials

The burial of a cadaver results in reduced arthropod activity and disruptions in colonisation patterns. Here, the distribution and diversity of mite taxa was studied across decomposition stages of shallowly buried pig carcasses (Sus scrofa domesticus). In total 300 mites (88 species) were collected from three pig shallow graves compared to 129 mites (46 species) from control (bare) soil samples at the same depth. A successional pattern of Acari higher taxa and families was observed, and species richness and biodiversity fluctuated throughout decomposition, whereas active decay showed the greatest biodiversity. Mesostigmata mites were the most abundant in ‘cadaver …

Media Frames And Abortion Issue Polarization, Shianne Galuska

Master's Theses

The abortion issue is one of the most polarizing topics within the public and media sphere. How the media chooses to frame the abortion debate may influence public opinion and individual reactions. Specifically, articles that use incongruent abortion frames (pro-life/pro-abortion & anti-abortion/pro-choice) may be contributing to an ingroup versus outgroup mentality by highlighting who is the ingroup and who is the outgroup, thus generating moral disgust and polarization (characterized by anger, bias, and activism) amongst those with opposing views. This study sought to answer whether presenting individuals with an incongruent abortion frame increases anger, bias, and activism (polarization), as well …

Free-Floating Immunostaining Of Mouse Brains, Longlong Tu, Nan Zhang, Kristine M Conde, Jonathan C Bean, Chunmei Wang, Yong Xu

Children’s Nutrition Research Center Staff Publications

Immunohistochemical staining of mouse brains is a routine technique commonly used in neuroscience to investigate central mechanisms underlying the regulation of energy metabolism and other neurobiological processes. However, the quality, reliability, and reproducibility of brain histology results may vary among laboratories. For each staining experiment, it is necessary to optimize the key procedures based on differences in species, tissues, targeted proteins, and the working conditions of the reagents. This paper demonstrates a reliable workflow in detail, including intra-aortic perfusion, brain sectioning, free-floating immunostaining, tissue mounting, and imaging, which can be followed easily by researchers in this field.

Also discussed are …

Using Bibliometrics To Evaluate Outcomes And Influence Of Translational Biomedical Research Centers, Kristine M. Bragg, Gwen C. Marchand, Jonathan C. Hilpert, Jeffrey L. Cummings

Educational Psychology, Leadership, and Higher Education Faculty Research

Introduction. Federal grant funding to support infrastructure development of translational biomedical research centers is a form of public health intervention. Establishing rigorous methods for measuring center success and outcomes is essential to justify continued funding. Methods. Bibliometric data compiled from a 5-year funding cycle of a neurodegeneration and translational neuroscience research center was analyzed using the package bibliometrix for open source software R and the NIH-developed research tool iCite. Results. The research team and their collaborators (n=485) produced 157 grant-citing publications from 2015-2020. The science was produced by small research teams clustered around three main communities of topics: Alzheimer's Disease, …

Collaborative Metaphor Analysis Research Methodology: A Retrospective Self-Study, Donita Shaw, Sue Christian Parsons, Sheri Vasinda

The Qualitative Report

The purpose of this manuscript is to explicate the metaphor analysis process we employed in a recent study to make this methodology more accessible to future researchers. To explain and demystify metaphor analysis as a method, we describe in detail the three rounds of data analysis leading to findings. We seek to make transparent the messiness and thoughtfulness of the refining process as well as the methodological rigor and trustworthiness. In the discussion that follows, researchers share experiences with and resulting insights into the methodology in hopes of providing future researchers with support for their own metaphor analysis work.

Rn7sk Small Nuclear Rna Controls Bidirectional Transcription Of Highly Expressed Gene Pairs In Skin, Roberto Bandiera, Rebecca E Wagner, Thiago Britto-Borges, Christoph Dieterich, Sabine Dietmann, Susanne Bornelöv, Michaela Frye

Open Access Publications

Pausing of RNA polymerase II (Pol II) close to promoters is a common regulatory step in RNA synthesis, and is coordinated by a ribonucleoprotein complex scaffolded by the noncoding RNA RN7SK. The function of RN7SK-regulated gene transcription in adult tissue homoeostasis is currently unknown. Here, we deplete RN7SK during mouse and human epidermal stem cell differentiation. Unexpectedly, loss of this small nuclear RNA specifically reduces transcription of numerous cell cycle regulators leading to cell cycle exit and differentiation. Mechanistically, we show that RN7SK is required for efficient transcription of highly expressed gene pairs with bidirectional promoters, which in the epidermis …

Inhibition Of The Nlrp3 Inflammasome Improves Lifespan In Animal Murine Model Of Hutchinson-Gilford Progeria, Alvaro González-Dominguez, Raúl Montañez, Beatriz Castejón-Vega, Jéssica Nuñez-Vasco, Débora Lendines-Cordero, Chun Wang, Gabriel Mbalaviele, José M Navarro-Pando, Elísabet Alcocer-Gómez, Mario D Cordero

Open Access Publications

Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson-Gilford progeria syndrome (HGPS). In this study, we present evidence of increased expression of the components of the NLRP3 inflammasome pathway in HGPS skin fibroblasts, an outcome that was associated with morphological changes of the nuclei of the cells. Lymphoblasts from HGPS patients also showed increased basal levels of NLRP3 and caspase 1. Consistent with these results, the expression of caspase 1 and Nlrp3, but not of the other inflammasome receptors was higher in the heart and liver of Zmpste24

Beyond Sperm And Male Accessory Gland Proteins: Exploring Insect Reproductive Metabolomes, Francesca Scolari, Fathiya M. Khamis, Diana Pérez-Staples

All Peer-Reviewed Publications

Insect seminal fluid, the non-sperm component of the ejaculate, comprises a variegated set of molecules, including, but not limited to, lipids, proteins, carbohydrates, salts, hormones, nucleic acids, and vitamins. The identity and functional role of seminal fluid proteins (SFPs) have been widely investigated, in multiple species. However, most of the other small molecules in insect ejaculates remain uncharacterized. Metabolomics is currently adopted to deepen our understanding of complex biological processes and in the last 15years has been applied to answer different physiological questions. Technological advances in high-throughput methods for metabolite identification such as mass spectrometry and nuclear magnetic resonance (NMR) …

The George-Anne, Georgia Southern University

The George-Anne

• LUNDSFORD OUT, INTERIM BRINGS BIG WIN
• Pregame Fail
• Join our Newsletter
• News Briefs
• What Twitter Said About The Firing Of Chad Lunsford
• Defensive lineman suspended after chugging beer atop moving yellow bus
• How to Set Goals
• Being Black at a PWI
• My Life as a COVID-19 Long Hauler
• A Look Into Suicide Prevention
• Yoga Guide: Beginners Edition
• Kemp and the "Aids vaccine"
• Public Health Dean questions mask mandates; effects on learning
• Education has no age

Receiver Apprehension & Listener Style Retention, Karlene T. Clark

Librarian Posters and Presentations

Receiver apprehension is the anxiety patrons feel when approaching someone for help. There are different types of ways in which people process information, some of which can be a detriment to the person hoping to learn something or just have a question answered. This presentation looks at the different styles of listeners and how librarians can utilize this knowledge to better meet the needs of patrons coming to the reference desk for assistance.

Avian Reproductive Success Is Associated With Multiple Vegetation Characteristics At An Active Grassland Restoration Site In Central Georgia, Kayla Allen, Katie Stumpf

Georgia Journal of Science

Grassland bird populations are experiencing major declines due to habitat degradation, pesticide use, and fire suppression throughout North America. Large-scale grassland restoration efforts to improve and provide suitable habitat are ongoing, but there is little data on productivity of birds breeding in restored habitats, nor on the impact of specific vegetation characteristics on reproductive success. Since 2005, agriculture fields at Panola Mountain State Park in central Georgia have been undergoing restoration to warm-season grasslands; however, until now, data on nest success or productivity was lacking. The goals of this project were to: (1) quantify reproductive success and (2) determine which …

Learning During A Pandemic: The Impact Of Digital Badges On Staff Training, Jennifer Wright

South Carolina Libraries

During the pandemic, the Spartanburg County Public Libraries implemented a new learning management system with a digital badging component. The digital badges were enthusiastically received by staff and increased training completion rates significantly. Even without an LMS, other libraries can create badging for continuing education using a variety of online resources. Digital badging is an important motivational tool to use for continuing education, especially as training goes virtual due to the COVID-19 pandemic.

Full Issue

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

No abstract provided.

California North Coast Vehicle And Human Use Beach Survey Of False Klamath Cove, Ruthie A. Maloney, John W. Corbett

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

This study looks to provide accurate, base-line-data of north coast beach usage and will identify activities in the vicinity of False Klamath Cove (FKC) bird sanctuary, which is a giant smokestack rock bird rookery of some 40,000 seabirds called False Klamath Rock. A research review showed that the north coast does not have adequate statistical information for FKC nor on other north coast beach areas for beach use. In the absence of such local data other beach studies are used. Most of these surveys are in beach areas of Southern California. Such extrapolations often result in an overestimation of beach …

Eddylines, Ann Nehaya Walsh

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

No abstract provided.

Effects Of Redwood Bark And Leaf Leachate On Different Lichen Populations Found Within The Redwood Forest Of Arcata, Ca, Courtney Michelle Harris, Phoebe Hughes

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

No abstract provided.

A Historical And Contextual Review Of The Adverse Psychological Effects Of The Trauma Of Colonialization On Alaska Native Peoples, Gwendolyn Barnhart, Andrew D. May

Psychology from the Margins

Through a historical review, the authors sought to provide an analysis of the adverse psychological effects of the traumatization of colonialization in Alaska Native Peoples. In the context of oppression, the authors discuss the potentially harmful implications of approaching psychology from a framework development largely out of Western philosophical thought and the medical model. In an attempt to be more culturally sensitive to the unique history and needs of Alaska Natives, the contextual FHORT model is proposed as a more appropriate conceptual framework to start from. Details of the various facets of colonialization and their associations and suspected contributions to …

Extensive Livestock Production And Emerging Social Ethics For Animals, Bernard E. Rollin

IGC Proceedings (1977-2023)

The last 50 years have witnessed a dazzling array of social ethical revolutions in Western society. Such moral movements as feminism, civil rights, environmentalism, affirmative action, consumer advocacy, homosexual rights, children’s rights, the student movement, antiwar activism, public rejection of biotechnology, have forever changed the way governments and public institutions comport themselves. And this is equally true for private enterprise; to be successful, businesses must be seen as operating solidly in harmony with changing and emerging social ethics. It is arguable that morally based boycotting of South African business was instrumental in bringing about the end of apartheid, and similar …

The Importance Of Animal Comfort For Animal Production In Intensive Grassland Systems, P. H. Hemsworth, J. L. Barnett

IGC Proceedings (1977-2023)

Animals utilise a wide range of regulatory systems to control the conditions within their bodies or homeostasis. These regulatory systems control for example, body temperature, nutritional state, water balance, social interactions and fear and these systems react to environmental and endogenous stimuli so as to correct or prevent displacements from the optimal range. The behavioural and physiological responses utilised by the animal are usually proportional to the challenge to homeostasis. The stress response commences with the central nervous system perceiving a potential challenge to homeostasis. Once the central nervous system perceives a threat, it develops a biological response or defence …

Effect Of Caloric Stress On Milk Production And Animal Comfort, Mónica B. Sacido, F. Loholaberry, N. Sánchez, J. Intruvini

IGC Proceedings (1977-2023)

The objective of this study was to determine the effect of the environmental factors on the animal behaviour of grazing dairy cows, estimated through the THI (Temperature-Humidity Index) and the relationship with the daily milk production, quality of milk, consumption and the detection of zeal. The study was carried out in Azul , in the province of Buenos Aires, Argentina and was developed from December 1999 to February 2000. The effect of the half shade was quantified based on the production in litres of milk/day, % protein, % fat and detection of zeal. In the period analyzed, the THI usually …

Dags In Sheep Grazing Temperate Pastures: Causes And Consequences Of Faecal Adhesion To Wool, Garry C. Waghorn

IGC Proceedings (1977-2023)

Dags are the accumulation of faeces on wool in the perianal (breech) region of sheep and are a common problem in sheep fed good quality ryegrass based pastures in New Zealand. Their removal, or prevention, is costly but the consequences of doing nothing are severe. There is a high correlation between dags and flystrike (development of maggots) on sheep with dags, and dags reduce fleece value, live-weight gain and reproductive performance. Information summarised here suggests a range of factors contribute to the incidence of dags: lush (high quality) feeds, high voluntary feed intakes, presence of parasites in the gastro-intestinal tract, …

Jordan's Public Policy Response To Covid-19 Pandemic: Insight And Policy Analysis, Wa’Ed Alshoubaki, Michael Harris

Public Administration Faculty Research

The aim of this study was to gain an understanding of how the Jordanian government has responded and continues to respond to the COVID-19 pandemic. It utilizes the interpretive policy analysis approach through document analysis. The analysis showed that Jordan created social protection policies to assist people who lost their jobs or whose work was suspended due to the coronavirus. The economic policies build solidarity and facilitate the private sector’s recovery. The health care measures firmly applied included lockdown, wearing masks, and restrictions on gatherings and public events. Jordan uses hard power and imposes sanctions on any violation that threatens …

Curriculum Subcommittee Agenda, October 6, 2021, Utah State University

Educational Policies Committee

• Approval of 2 September 2021 Minutes
• Program Proposals
• Semester Course Approval Reviews
• Other Business

Educational Policies Committee Minutes, October 6, 2021, Utah State University

Educational Policies Committee

• Approval of 2 September 2021 Minutes
• Curriculum Subcommittee Report
• Academic Standards Subcommittee Report
• General Education Subcommittee Report
• Other Business

Hindlimb Suspension In Wistar Rats: Sex-Based Differences In Muscle Response, Marie Mortreux, Megan E. Rosa-Caldwell, Ian D. Stiehl, Dong-Min Sung, Nicholas T. Thomas, Christopher S. Fry, Seward B. Rutkove

Athletic Training and Clinical Nutrition Faculty Publications

Ground-based animal models have been used extensively to understand the effects of microgravity on various physiological systems. Among them, hindlimb suspension (HLS), developed in 1979 in rats, remains the gold-standard and allows researchers to study the consequences of total unloading of the hind limbs while inducing a cephalic fluid shift. While this model has already brought valuable insights to space biology, few studies have directly compared functional decrements in the muscles of males and females during HLS. We exposed 28 adult Wistar rats (14 males and 14 females) to 14 days of HLS or normal loading (NL) to better assess …