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“We Are Working For A Caste-Free India”: An Interview With M. M. Vinodini, Bonnie Zare

Journal of International Women's Studies

The present interview with M.M. Vinodini extends the context of her two stories printed in this issue, “Block” and “Villain’s Suicide” and the contemporary context for Telugu Dalit women writers. It enables readers to consider the combination of factors that must align for a woman and therefore, a secondary citizen of a severely stigmatized community to take action and protest through activist organizing and creative storytelling. Discrimination, self-respect, and assertion are repeated themes in Vinodini’s body of work and here she discusses changing views of caste among young people, the reception of her work, the ongoing mistreatment of sanitation workers, …

Inhibitory Learning Theory And Emotional Processing Theory For Proper Extinction Learning In Specific Phobias: A Comprehensive Comparison, Arturo Peña

McNair Scholars Research Journal

Emotional processing theory (EPT) is the underlying framework for traditional exposure therapy (Barlow, 2004). EPT relies on a process known as habituation, presuming that the amount of fear reduction from peak fear levels within an exposure therapy session predicts successful extinction learning. Prevailing research in behavioral psychology challenges the EPT framework for its capacity to accurately predict long-term extinction learning. Inhibitory learning theory (ILT) offers a different approach to exposure therapy, centered around forming new non-threat associations (e.g., memories) by way of fear acceptance rather than attempts to down-regulate aversive emotions (Craske et al., 2008). By examining pertinent literature on …

Life In The Fast Lane: Is The Pace-Of-Life Syndrome Supported In Tarantulas?, Peter Landor

McNair Scholars Research Journal

Pace-of-Life Syndrome (PoLS) hypothesizes that there is a correlation between life history, behavior, and physiology along an axis from slow to fast. Fast-paced species reach sexual maturity faster while also exhibiting faster growth rates, which, in turn, correspond to a higher rate of metabolism. Tarantulas are good model organisms for studying PoLS because species fit along the spectrum from very slow-growing species to species that mature, reproduce, and die within a relatively short time span. Our study will determine if the PoLS is supported in tarantulas. Specifically, we compared species with different lifespans and measured metabolic rates and growth rates. …

Mental Health Stigma Amongst Adolescents: Causes And Solutions Thereof, John Michael Garcez

McNair Scholars Research Journal

Mental health is one of the most prevalent issues in our society today, especially amongst adolescents. A 2018 survey from the Substance Abuse and Mental Health Services Administration (SAMHSA) found that 14.4% of the U.S. teenagers surveyed had experienced a major depressive episode in the past year, an increase of 6.1% from their 2008 survey (SAMHSA, 2019). Given that mental health issues are more widespread than ever, especially during a pandemic, it is imperative to study barriers to mental health treatment, with one of these being stigma. As Nearchou et al. (2018) explained, stigmatization leads to individuals not seeking treatment …

Gastrointestinal Nematode Infections In Grazing Domestic Ruminants, M. Eysker

IGC Proceedings (1977-2023)

World wide gastrointestinal nematode infections impair production of ruminants. Particularly in small ruminants control of these infections is seriously hampered by the development of resistance of the parasites against anthelmintic drugs. This implies that alternative control measures have to be implemented in order to maintain a sustainable ruminant industry. In this paper the various possibilities to achieve this are briefly discussed. The possibilities discussed include grazing management, vaccination, selective breeding, biological control, nutrition and the use of bioactive forages such as for instance plants containing condensed tannins. At the end it is concluded that combinations of these options should preferably …

Plant Secondary Compounds; Their Impact On Forage Nutritive Value And Upon Animal Production, T. N. Barry, D. M. Mcneill, W. C. Mcnabb

IGC Proceedings (1977-2023)

Both the anti-nutritional and beneficial effects of secondary compounds in a range of temperate and tropical forages have been reviewed. Major secondary compounds in temperate and tropical forage plants occur in the phenolic fraction and include condensed and hydrolysable tannins, phenolic monomers and lignin. Condensed tannins (CT) bind to plant protein by pH-reversible hydrogen bonding. In temperate legume forages this reduces rumen protein degradation and can increase the absorption of essential amino acids (EAA) from the small intestine, with reactivity depending on CT concentration, molecular weight and chemical structure. Low concentrations of CT in Lotus corniculatus (20-40g/kg DM) increased EAA …

A Strategy For Detecting Natural Anthelmintic Constituents Of The Grassland Species Plantago Lanceolata, D. L. Gustine, M. A. Sanderson, J. Getzie, S. Donner, R. Gueldner, N. Jennings

IGC Proceedings (1977-2023)

A strategy to detect anthelmintic constituents in plantain (Plantago lanceolata) using a bioassay-driven purification approach was tested. Plantain consumed by cattle may control or reduce internal parasite titers, possibly due to the iridoid glucoside aucubin. Lyophilized, ground leaves of wild P. lanceolata were extracted with 95 % ethanol or boiling water containing calcium carbonate. Partially purified extracts (0 to 250 mg ml^-1), 5 μg ml^-1 of the anthelmintic levamisole, or 5 mg ml^-1 of aucubin were tested with sheathed bovine parasites (Ostertagia ostertagi). The percent moving worms was unchanged for water controls …

Shirley Ann Williams And Joseph L. Williams Jr. -- Part 2, Kelli Johnson

Oral Histories – NPS AACR Civil Rights In Appalachia Grant

Part 2 of Kelli Johnson's oral history interview with Shirley Ann and Joseph L. Williams Jr..

This oral history is part of the National Park Service African American Civil Rights History and Appalachia Grant Program.

Proceedings - Climate Change: Threats, Risks And Vulnerabilities, Centre For Business And Economic Research (Cber), Hanns Seidel Foundation, Pakistan

Conference Proceedings

Pakistan is one of the world’s most climate vulnerable countries ranking fifth in the list. It has experienced various disasters in recent decades, including floods, droughts and intense heat waves causing thousands of fatalities. Moreover, due to the deterioration of the Indus Delta approximately 1.2 million people dispersed and shifted to urban hubs like Karachi. Researchers have projected an increase in frequency and severity of these catastrophic environmental events, causing food and water scarcity, health and socio-economic issues in coming decades.

Climate change is no longer a threat but has become an existential crisis. There is a need for immediate …

High-Fat Diet-Induced Obese Effects Of Adipocyte-Specific Cxcr2 Conditional Knockout In The Peritoneal Tumor Microenvironment Of Ovarian Cancer, Deokyeong Choe, Eun-Sook Lee, Alicia Beeghly-Fadiel, Andrew J. Wilson, Margaret M. Whalen, Samuel E. Adunyah, Deok-Soo Son

Chemistry Faculty Research

Obesity contributes to ovarian cancer (OC) progression via tumorigenic chemokines. Adipocytes and OC cells highly express CXCR2, and its ligands CXCL1/8, respectively, indicating that the CXCL1/8-CXCR2 axis is a molecular link between obesity and OC. Here, we investigated how the adipocyte-specific CXCR2 conditional knockout (cKO) affected the peritoneal tumor microenvironment of OC in a high-fat diet (HFD)-induced obese mouse model. We first generated adipocyte-specific CXCR2 cKO in mice: adipose tissues were not different in crown-like structures and adipocyte size between the wild-type (WT) and cKO mice but expressed lower levels of CCL2/6 compared to the obese WT mice. HFD-induced obese …

The Diamond, October 8, 2021, Dordt University

Dordt Diamond

• Front Page: Dordt University, Hoekstra, Ask Sioux Center for $2 Million; Art, But in the Prairie; Peter and the Starcatcher: Belonging and Family
• News: Dr. Culpepper Shares the Story of The Book; Smit to Depart for a Year; F.L.A.M.E.'s 55th Open in Mornings; Music with Friends; Defender Forever: A New Way to Stay Connected
• Arts & Entertainment: Dear Evan Hansen... ; Dear Evan Hansen and Mental Health; Super Fascia: A Glimpse into the Human Mind
• Opinion: The Bike Bandwagon; Album Review: Montero by Lil Nas X; The Op-Ed is Dead
• Feature: Vero's Taco …

Prioritization Of Molecular Targets For Antimalarial Drug Discovery, Barbara Forte, Daniel E Goldberg, Eva S Istvan, Et Al

2020-Current year OA Pubs

There is a shift in antimalarial drug discovery from phenotypic screening toward target-based approaches, as more potential drug targets are being validated in

Damaschke '85 Accepts Tony Awards For Best Musical, Kailee Galloway

News and Events (Discontinued Series)

No abstract provided.

Braf Mutations May Identify A Clinically Distinct Subset Of Glioblastoma, Samantha N Mcnulty, Katherine E Schwetye, Cole Ferguson, Chad E Storer, George Ansstas, Albert H Kim, David H Gutmann, Joshua B Rubin, Richard D Head, Sonika Dahiya

Open Access Publications

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Prior studies examining the mutational landscape of GBM revealed recurrent alterations in genes that regulate the same growth control pathways. To this regard, ~ 40% of GBM harbor EGFR alterations, whereas BRAF variants are rare. Existing data suggests that gain-of-function mutations in these genes are mutually exclusive. This study was designed to explore the clinical, pathological, and molecular differences between EGFR- and BRAF-mutated GBM. We reviewed retrospective clinical data from 89 GBM patients referred for molecular testing between November 2012 and December 2015. Differences in tumor mutational profile, …

Assessment Of Sewage Workers’ Exposure To Hazardous Materials In Iraq: Sewage Workers Exposure And Hazardous Materials, Estabraq Alwasiti

Iraqi National Journal of Medicine

Background:Sewage workers, who maintain the sewage system and provide an essential service for public health protection, may come in direct contact with sewage hazards which then may induce DNA damage and oxidative stress. The aim of this studyis to assess the level of nitric oxide, homocysteine, 8 OHdG, and vitamin s A & E in the plasma of sewage workers for different periods of exposure.Results:Nitric oxide, vitamin A, and vitamin E showed a significant reduction in sewage workers when compared with anon-exposed control group. However, homocysteine and 8 OHdGlevels were increased in sewage workers when compared with thenon-exposed control group.Conclusions:Sew …

Ghb Dependent Changes In Pea-15 Gene Expression In Different Human Cell Lines: Ghb Dependent Changes In Pea-15 Gene Expression In Different Human Cell Lines, Asia Abdullah, Elizabeth Elli

Iraqi National Journal of Medicine

Background. Gamma-hydroxybutyric acid (GHB) is found to be present endogenously in mammalian brains. It has been abused increasingly in recent years, particularly in date rape sexual assaults. Metabolism of GHB happens very rapidly; it disappears within 12 hours, making its detection in criminal cases very complicated._x000D_ Aim. This study intended to determine whether PEA-15 gene expression in human cell lines can be used as a marker for expanding the window of GHB detection beyond 12 hours._x000D_ Methods. The effects of GHB on cell viability was determined by use of the MTT assay. Quantitative real-time PCR and western blots were used …

Human Astrovirus Among Children With Cancer In Basrah: Human Astrovirus Among Children With Cancer In Basrah, Morroge Jassim, Janan Hasan, Hassan Hasony

Iraqi National Journal of Medicine

Background. The impairment of the T-lymphocyte system leads to reduced viral clearance, resulting in intensified disease and the possibility of prolonged infection.(2) The poor functioning of B lymphocytes makes the host susceptible to bacterial and viral infections, especially in cases of malignant disease._x000D_ Aim of the study. The present study set out to determine the frequency of human astrovirus infection among patients who suffered from malignancies who were being treated in the Oncology Center of the Basrah Children’s Specialty Hospital._x000D_ Patients and Method. A cross-sectional study was approved for a population of children with cancers during the period from October …

Writing And Linguistics News, Georgia Southern University

Writing & Linguistics News (2012-2022)

• Georgia Poetry Circuit presents Paisley Rekdal on November 11

Teaching Advanced Technology With Higher Education: Computer Animation, Film Production And Broadcasting, Erika Grodzki, Mark Coné, Leslie Wing Orúe, John Conway, Hung Chum Kao

Faculty and Staff Publications & Presentations

This panel will discuss the current industry trend of Animation Technology and how it effects and changes the higher education from the history of Animation & Film, 2d & 3D Animation, Motion Graphic Animation and Motion Capture Animation fields. Through this presentation and peers discussions we should have a strong understanding of how the modern animation technology transform the traditional animation in current industry and higher education.

Humboldt In The Time Of Covid - Digital Achieve, Viviana Sanchez

Humboldt in the Time of COVID - Digital Archive

• "The overview of my project was to a look into a student or resident of Humboldt County in their day to day lives, their outlook on COVID-19, and how it has affected them mentally.
• Items that were talked about that are related to COVID-19, are the challenges they faced and the impact it has put on them either mentally, financially, or physically.
• The participants live in both Eureka and Arcata which help to get a feel or both cities and the outlook COVID has on them either in the major or minor city.
• The main subjects in my study were …

Determining The Accuracy Of Holstein Bull Semen Prices With A Two-Tier Efficiency Model, Loren W. Tauer

Journal of Applied Farm Economics

The pricing accuracy of dairy bull semen available for artificial insemination is investigated using a price model cast in terms of a two-tier efficiency model, which allows estimating an overprice and underprice given the net return the bull’s daughter is expected to contribute to the farm based upon the transmittable trait characteristics of a bull. The estimation produces statistically significant coefficients, including the coefficients for the overpricing and underpricing of the semen. The average estimate of overpricing is around 25%, and the average estimate of underpricing is around 33%. As expected, low semen prices tend to be underpriced and high …

Farm Efficiency And Productivity Growth: The Effect Of Commodity Prices, Elizabeth Canales, Jason S. Bergtold, Allen Featherstone

Journal of Applied Farm Economics

Crop prices can affect farm productivity through input- output decisions. This study assesses the relationship between crop prices and productivity changes among a sample of Kansas farms. The changes in total factor productivity are evaluated using a nonparametric approach with a Malmquist productivity index and potential drivers of technical efficiency and productivity change are analyzed. Farms with higher leverage and greater diversification are likely to be more efficient and experience productivity change. Lower productivity occurred during years with higher crop prices, suggesting that innovation is more likely to occur when margins are tight.

Tree Competition Reduces Cattle Growth Rates In Eucalypt Woodlands Of Queensland, T. J. Hall, J. R. Douglas

IGC Proceedings (1977-2023)

The wiregrass/bluegrass (Aristida/Bothriochloa) native pasture community in Eucalypt woodlands is a major cattle producing resource in Queensland. The effects of poplar box tree (Eucalyptus populnea) competition (at 5 m²/ha tree basal area) and grazing pressure on pastures and on growth of Brahman-cross steers were measured in a grazing experiment. Treatments were 2 tree competition levels (live trees or clearing) by 3 grazing pressures (low - 25%, medium - 50% and high - 75% utilisation of annual pasture growth). Pasture yield and pasture foliage cover increased for 3 years from the reduction in tree competition …

Perloline, The Forgotten Plant Alkaloid, L. P. Bush

IGC Proceedings (1977-2023)

Perloline, a biologically active plant alkaloid, accumulated in vegetative tissue of tall fescue during the summer months. Perloline content increased with increased available nitrogen and light. Total perloline accumulation was greatest with NO₃-N fertilizer, but greatest perloline content per unit of dry wt was measured with NH₄-N. In mature plants greatest perloline accumulation occurred in the leaves and immature inflorescences, but was not detected in the seed. Leaves of meadow fescue contained the greatest amounts of perloline, tall fescue was intermediate and giant fescue, and ryegrasses and yellow foxtail had low amounts of the alkaloid. Tryptophan …

Bloat In Ruminants: The Cell Rupture Hypothesis, B. P. Berg, T. A. Mcallister, K.-J. Cheng

IGC Proceedings (1977-2023)

An alfalfa (Medicago sativa L.) cultivar with a low initial rate of digestion (LIRD), AC Grazeland B, was developed to test the hypothesis that the rate of cell rupture was a cause of frothy bloat in cattle or sheep. The amount of cell wall increases and digestibility declines as plants mature. Thus the cell rupture theory also predicts that the bloat potential of alfalfa is related to maturity. This study compared the digestibility of cell walls (NDF) in LIRD cultivars with that of a standard, Beaver, in relation to maturity and bloat incidence. Fresh alfalfa was fed to wethers …

Effect Of Storage Time And Temperature On Recovery Of Synergistes Jonesii From Rumen Fluid And Feces, W. M. Andrew, M. J. Williams, M. J. Allison, C. C. Chase Jr., C. G. Chambliss, R. S. Kalmbacher, W. E. Kunkle

IGC Proceedings (1977-2023)

Synergistes jonesii is a rumen bacterium that degrades 3,4-dihydroxypyridine (3,4 DHP), the toxic breakdown product of mimosine in leucaena (Leucaena leucocephala). Fecal culture is the most practical way to determine S. jonesii presence in zoological ruminants, particularly if feces can be collected from night penning facilities. Fresh rumen fluid and fecal or fecal slurry (sheep [Ovis spp.] only, 1:4 wt to vol. feces and culture media) from cattle (Bos spp.) and sheep, known to be colonized by S. jonesii, were subjected various storage times (0, 6, 12, and 24 h) and temperatures (5, 23, and …

Intein Inhibitors As Novel Antimicrobials: Protein Splicing In Human Pathogens, Screening Methods, And Off-Target Considerations, Diana A. Wall, Chunyu Wang, Kenneth Mills, Christopher W. Lennon

Faculty & Staff Research and Creative Activity

Protein splicing is a post-translational process by which an intervening polypeptide, or intein, catalyzes its own removal from the flanking polypeptides, or exteins, concomitant with extein ligation. Although inteins are highly abundant in the microbial world, including within several human pathogens, they are absent in the genomes of metazoans. As protein splicing is required to permit function of essential proteins within pathogens, inteins represent attractive antimicrobial targets. Here we review key proteins interrupted by inteins in pathogenic mycobacteria and fungi, exciting discoveries that provide proof of concept that intein activity can be inhibited and that this inhibition has an effect …

Tartuffe By Molière

Theatre Programs

No abstract provided.

Cellular Origins Of Egfr-Driven Lung Cancer Cells Determine Sensitivity To Therapy, Fan Chen, Jinpeng Liu, Robert M. Flight, Kassandra J. Naughton, Alexsandr Lukyanchuk, Abigail R Edgin, Xiulong Song, Haikuo Zhang, Kwok-Kin Wong, Hunter N. B. Moseley, Chi Wang, Christine F. Brainson

Toxicology and Cancer Biology Faculty Publications

Targeting the epidermal growth factor receptor (EGFR) with tyrosine kinase inhibitors (TKIs) is one of the major precision medicine treatment options for lung adenocarcinoma. Due to common development of drug resistance to first- and second-generation TKIs, third-generation inhibitors, including osimertinib and rociletinib, have been developed. A model of EGFR-driven lung cancer and a method to develop tumors of distinct epigenetic states through 3D organotypic cultures are described here. It is discovered that activation of the EGFR T790M/L858R mutation in lung epithelial cells can drive lung cancers with alveolar or bronchiolar features, which can originate from alveolar type 2 (AT2) cells …

Systematic Review Of Polyherbal Combinations Used In Metabolic Syndrome, Amber Hanif Palla, Faridah Amin, Bilqees Fatima, Arooj Shafiq, Najeeb Ur Rehman, Ikram Ul Haq, Anwar-Ul-Hassan Gilani

Department of Biological & Biomedical Sciences

Background: Metabolic syndrome (MetS) is a multifactorial disease, whose main stay of prevention and management is life-style modification which is difficult to attain. Combination of herbs have proven more efficacious in multi-targeted diseases, as compared to individual herbs owing to the "effect enhancing and side-effect neutralizing" properties of herbs, which forms the basis of polyherbal therapies This led us to review literature on the efficacy of herbal combinations in MetS.
Methods: Electronic search of literature was conducted by using Cinnahl, Pubmed central, Cochrane and Web of Science, whereas, Google scholar was used as secondary search tool. The key words used …