Digital Commons Network^™

Forgotten In Local Jails: A Carceral System Created To Fail Women., Hayley Jackey

Online Theses and Dissertations

The United States has seen an influx of incarcerated women since the 1980s with a 750% increase between 1980 and 2017. There is a substantial amount of literature about how women experience prison and the unique challenges they face as they reenter society such as motherhood, previous abuse, mental health, and housing. Conclusions drawn suggest that the current structure fails to prepare women for a society that denounces women who have been incarcerated. What is less known is how this research translates to the jail environment. For reasons to be discussed, it is likely that local jails are even less …

The Phylogenetic Analysis Of Genes Encoding Specific Steps In The Glutathione Pathway Within Industrial Beer Brewing Strains: Saccharomyces Cerevisiae, Saccharomyces Pastorinus, And The Spoilage Microbe Brettanomyces, Miles Tyler Johnson

Online Theses and Dissertations

The Glutathione pathway, (GSH) is an antioxidant system in yeast that increases cell viability and contributes to the production of desirable beer flavors during industrial fermentation. Despite its importance, studies using the GSH pathway: GSH1, GSH2, GLR1, and SOD1 genes, to trace the evolutionary history of beer strains are lacking. As a result, the investigator sought to elucidate the phylogenetic relationships between four commonly used industrial beer strains: California Ale, London Ale, Oktoberfest, and Brettanomyces bruxellensis through single-gene sequencing analysis of the GSH pathway. It was hypothesized that the actions of these GSH genes are unique and potentially upregulated in …

Not Angry But Angy: The Rhetorical Effects Of Non-Standard Language In Memes, Cailin Rhiannon Wile

Online Theses and Dissertations

The use of non-standard language on the internet has long been a topic of controversy, as some believe its prevalence indicates carelessness or a lack of intelligence in the (mostly) younger generations who use it. Non-standard language can refer to spelling or grammar that deviates from preferred language conventions, and is popular in what are called internet “memes.” Though the definition of a “meme” can vary, the term can be used to refer to pieces of culture that are remixed and disseminated by internet users. This thesis identifies patterns of non-standard language in memes to demonstrate that these changes are …

Lifeglows Through The Anthropocene: Development Of The Radical Imagination And Response-Ability Within Superhero Comics, Reed G. Puc

Graduate Student Theses, Dissertations, & Professional Papers

Scholars such as Amitav Ghosh, Timothy Clark, and Timothy Morton emphasize the importance of and challenge within the task of representing the power, scope, and scale of climate change in art and literature. These interrogations often emphasize the failures of extant works to animate their viewers towards action in a time of environmental crisis, but struggle to find any work that meets their expectations. This ‘game-over’ attitude, I argue, is the direct result of the cruel optimism present in the current scholarship’s attachment to ‘traditional’ forms of art and literature. By interrogating the conclusions Ghosh reaches about the novel’s function …

The Worm In Heaven, Daniela Rae Garvue

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

A Personal History Of Invasive Hands And Endangered Lovers, Samuel Paul Boudreau

Graduate Student Theses, Dissertations, & Professional Papers

I thought I could be ridden hard and put away wet, wet, wet. I thought death and rape and drunkenness and unrequited love were functions of a typical life, a this-is-how-it-goes kinda world. But, as I’ve emerged from hellish muck, there has been a realization: the way we treat each other and the soil, the aching earth, needs to change. “A Personal History of Invasive Hands and Endangered Lovers” explores the relationship between intimacy and pain through a history of ecology and consumption, a melancholy of sorts. It amplifies trauma as a call-to-action and refuses to sit and take it. …

A Large Flock Of Small Birds: Essays, Rebecca Hanna Jacobson

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

Albuquerque, Suzanne Joy Garcia Pino

Graduate Student Theses, Dissertations, & Professional Papers

This story is about living in Albuquerque, New Mexico in 2017 as a mixed-race woman with Hispanic, European, and Indigenous Mexican and Puebloan ancestry. Albuquerque seeks to understand how marginalized cultures become subsumed and ultimately lost by the dominate culture. As a child of mixed heritage, I am interested in the internalization of this cultural disappearance, and all the subtle yet profound choices my ancestors have made: my grandparents refused to teach Spanish to their children so they would fit in better with the whites, my Indian great grandfather fled Mexico, leaving behind his tribe and culture, never to return. …

Overhearers’ Perceptions Of Familiarity Between Interlocutors In Computer-Mediated Communication Based On Gif Usage, Alexa F. Druckmiller

Master's Theses and Doctoral Dissertations

Given the ever-growing presence of computer-mediated communication (CMC), it is important to understand CMC and how it relates to communication in general. Despite considerable research on CMC, various features are still underrepresented, such as GIF communication. This study examines what GIF usage suggests about interlocutors’ social relationships. In particular, through a perception experiment among young adults, this study investigates how GIF usage affects perceptions of social closeness between interlocutors. I find that participants perceive interlocutors to be significantly closer when one responds to another with a GIF with embedded text instead of a text-only response, an effect that I link …

Development, Validity And Reliability Study Of A Compliance Scale For The Covid-19 Outbreak Prevention Recommendations, Eli̇f Köse, Esra Yazici, Ahmet Bülent Yazici, Abdülkadi̇r Aydin, Hasan Çeti̇n Ekerbi̇çer, Oğuz Karabay

Turkish Journal of Medical Sciences

Background/aim: During the intense periods of the COVID-19 pandemic, legal measures were taken for its containment. However, since legal precautions cannot be implemented continuously, hand washing, mask usage and obeying social distance rules are important in combating the pandemic. Complying with these rules is mostly individual decisions. The behavior of individuals has a prominent place in the course of the pandemic. In this study, we aimed to develop a scale which could measure compliance with outbreak measures. Materials and methods: This study was conducted in two stages after evaluation of the content validity of the item pool formed by the …

The Study Of Sirtuins In Breast Cancer Patients Before And After Radiotherapy, Nazli Helvaci, Hati̇ce Saraçoğlu, Oğuz Gali̇p Yildiz, Eser Kiliç

Turkish Journal of Medical Sciences

Background/aim: Targeting the new and unique proteins is an important medical strategy for treating breast cancer. It is quite important to find out proteins that have a role in the development of cancer. Sirtuins (SIRT) are well related in different physiological activities and connected with cancer. We aimed to determine the effect of radiotherapy on SIRT1 and SIRT2, which have not been yet been clarified as a tumor suppressor or promoter. Materials and methods: Twenty-two women with nonmetastatic breast cancer enrolled in the study. Blood samples were taken before and after radiotherapy, soluble SIRT1 and SIRT2 levels were determined with …

Wnt Signaling Pathway Activities May Be Altered In Primary Sjogren's Syndrome, Ahmet Karataş, Zühal Ömerci̇koğlu, Burak Öz, Adi̇le Ferda Dağli, Onur Çatak, Fazi̇let Erman, Kazim Şahi̇n, Nevzat Gözel, Süleyman Serdar Koca

Turkish Journal of Medical Sciences

Background/aim: Sjögren's syndrome (SS) is an autoimmune disease and its pathogenesis is still not completely clear. The wingless (Wnt)/ß-catenin pathway has recently been shown to play an important role in inflammation. This study aims to determine the serum and saliva levels of Dickkopf (DKK)1 and sclerostin and to evaluate Wnt-1 and Wnt-3a expression in the salivary gland in patients with primary SS. Materials and methods: This study included 30 patients diagnosed with SS, 30 patients diagnosed with systemic lupus erythematosus (SLE), and 29 healthy controls. Serum and saliva levels of DKK1 and sclerostin were measured and the expressions of Wnt1 …

Allergic Diseases In The Elderly Population: A Single-Center Experience, Eray Yildiz, Fati̇h Çölkesen, Şevket Arslan, Recep Evcen, Fi̇li̇z Sadi̇ Aykan, Mehmet Kilinç, Gökhan Ayteki̇n

Turkish Journal of Medical Sciences

Background/aim: Although allergic diseases are generally considered to be diseases of childhood and youth, the first symptoms of allergic diseases can be seen in old age sometimes. The aim of this study was to determine the prevalence and characteristics of allergic diseases in the elderly population admitted to the allergy unit on an outpatient basis. Materials and methods: The files of the patients who applied to our clinic's allergy unit during the 8-year period were retrospectively analyzed. The data of patients aged ≥ 65 years were obtained from the files of our allergy unit archive. Results: A total of 1272 …

Common Worlding Pedagogies: Opening Up To Learning With Worlds, Affrica Taylor, Tatiana Zakharova, Maureen Cullen

Research outputs 2014 to 2021

Common worlding is a collective pedagogical approach. It is also a deliberate move to open up education to worlds beyond narrow human preoccupations and concerns and beyond its standard framing as an exclusively social practice. In this article, we identify some of the guiding principles that underpin this approach and explain how they work out in practice. We do so by offering a selection of illustrative vignettes drawn from the Walking with Wildlife in Wild Weather Times early childhood research project in Canberra, Australia, and from the Witnessing the Ruins of Progress early childhood research collaboratory in Ontario, Canada.

Judges’ Evaluation Reliability Changes Between Identifiable And Anonymous Performance Of Hip-Hop Dance Movements, Nahoko Sato, Luke S. Hopper

Research outputs 2014 to 2021

© 2021 Sato, Hopper. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hip-hop competitions are performed across the world. In the recent inclusion in the 2018 Youth Olympic Games, the assessment of hip-hop performance is undertaken by a panel of judges. The purpose of this study was to determine the reliability of different visualisation tools utilised in the assessment of the hip-hop dance movements. Ten dancers performed basic rhythmic hip-hop movements which were captured …

The Right To Development, Integral Human Development, And Integral Ecology In The Amazon, Diane A. Desierto, Ilaria Schnyder Von Wartensee

Journal Articles

From the Article

This article discusses the reorientation of environmental protection in Amazonia away from the paradigm of individual and collective natural resource management of regional or global commons, to the more radical thesis of Integral Ecology as the vindication of human dignity, environmental stewardship and collective responsibility - a concept deeply related to the Church's own pioneering of Integral Human Development as the 'authentic development development of every person and of the whole person'. Under the concept of integral Ecology, we argue that this expressive elaboration of the Catholic Church's core social teaching of Integral Human Development ultimately hearkens …

Fiduciary Judgment Rules, Julian Velasco

Journal Articles

Because of the strong moral rhetoric and robust equitable remedies available in fiduciary law, it is not surprising to find lawyers and legal scholars seeking to expand the reach of fiduciary law principles into new relationships and new areas of law. However, expansion often does not work very well because of the demanding and pervasive nature of fiduciary duties. Thus, jurists often turn to the business judgment rule and its policy of underenforcement of fiduciary duties as a way to fit fiduciary law principles into other areas of law. The problem with this approach is that it is based on …

Tuesday Afternoons With Schlegel, Barry Cushman

Journal Articles

I confess that I’m not at all certain why I was invited to this distinguished gathering. I suppose that it’s because Schlegel and I are friends; but that just pushes the mystery back a remove. Because as Jack surely recognizes, it is not at all obvious that (or why) we should be friends. We are from different generations—Schlegel is my senior by nearly twenty years. I don’t imagine that anyone would suggest that our personal styles bear a strong resemblance to one another. And our approaches to scholarship are almost antagonistic. Jack’s message accompanying the invitation to this conference strongly …

Leverage, Randy J. Kozel

Journal Articles

Sometimes government operates by inducement rather than order. Congress distributes money to the states. A state grants funds to nonprofit organizations. An administrative agency offers wages and professional opportunities to its staff. A high school provides instruction to its students. In each situation, the government furnishes something of value. And in each situation, it asks something in return-whether implementation of a government program, forbearance from activities deemed inconsistent with operational goals, conduct in pursuit of an employment mission, or compliance with standards of academic discipline. Though they arise in different contexts, these varied forms of government action present the same …

Measuring The Art Of International Law, Mary Ellen O'Connell

Journal Articles

Social science methodology is a useful adjunct to law, but it cannot replace the humanist ideas that constitute law. Scholars developed social science at the end of the nineteenth century and were soon using it to measure and assess material facts associated with far older intellectual disciplines like law. They have been able to confirm facts about such issues as the origins and impact of law. These studies rely, however, on a humanist definition of the object of the study. Humanist methods reveal that law is the result of transcendent concepts developed through natural law method. By the early twenty-first …

Roe And Casey Were Grievously Wrong And Should Be Overruled, Charles J. Cooper, Richard W. Garnett, Peter A. Patterson, Brian W. Barnes, John D. Ohlendorf

Journal Articles

This essay, based on an amicus curiae brief filed in the Dobbs case, explains that the Roe and Casey decisions were "grievously wrong", that no traditional stare decisis considerations weigh in favor of retaining them, and that they should be overruled.

The Morality Of Fiduciary Law, Paul B. Miller

Journal Articles

Recent work of fiduciary theory has provided conceptual synthesis requisite to understanding core fiduciary principles and the structure of fiduciary liability. However, normative questions have received only sporadic attention. What values animate fiduciary law? How does, or ought, fiduciary law prove responsive to them?

Where in other areas of private law theory – notably, tort theory – pioneering scholars went directly at normative questions like these, fiduciary theory has been exceptional for the reticence shown toward them. The reticence is sensible. Fiduciary principles are the product of equity’s most extended and convoluted program of supplementing surrounding law. They span several …

Rethinking Protections For Indigenous Sacred Sites, Stephanie H. Barclay, Michalyn Steele

Journal Articles

Meaningful access to sacred sites is among the most important principles to the religious exercise of Indigenous peoples, yet tribes have been repeatedly thwarted by the federal government in their efforts to vindicate this practice of their religion. The colonial, state, and federal governments of this Nation have been desecrating and destroying Native American sacred sites since before the Republic was formed. Unfortunately, the callous destruction of Indigenous sacred sites is not just a troubling relic of the past. Rather, the threat to sacred sites and cultural resources continues today in the form of spoliation from development, as well as …

Negative-Value Property, Bruce R. Huber

Journal Articles

Ownership is commonly regarded as a powerful tool for environmental protection and an essential solution to the tragedy of the commons. But conventional property analysis downplays the possibility of negative-value property, a category which includes contaminated, depleted, or derelict sites. Owners have little incentive to retain or restore negative-value property and much incentive to alienate it. Although the law formally prohibits the abandonment of real property, avenues remain by which owners may functionally abandon negative-value property, as demonstrated recently by busts in certain coal and oil & gas markets. When negative-value property is abandoned, whether formally or functionally, the rehabilitation …

Dissenting From The Bench, Christine M. Venter

Journal Articles

This paper examines the oral dissents of Justices Antonin Scalia and Ruth Bader Ginsburg from the year 2000 to the times of their respective deaths. It explores the concept and purpose of oral dissent and details the kinds of cases in which each justice was more likely to orally dissent. The paper analyzes the kinds of rhetoric that each justice used to refer to their subject matter, and argues that Scalia's rhetoric evinces a view of the law as "autonomous", operating independently of the facts of the case. In contrast, Ginsburg's view espouses a view of the law as responsive …

Disruption Of Fdps/Rac1 Axis Radiosensitizes Pancreatic Ductal Adenocarcinoma By Attenuating Dna Damage Response And Immunosuppressive Signalling, Parthasarathy Seshacharyulu, Sushanta Halder, Rama Krishna Nimmakayala, Satyanarayana Rachagani, Sanjib Chaudhary, Pranita Atri, Ramakanth C. Venkata, Michel M. Ouellette, Joseph Carmicheal, Shailendra K. Gautam, Raghupathy Vengoji, Shuo Wang, Sicong Li, Lynette M. Smith, Geoffrey A. Talmon, Kelsey Klute, Quan P. Ly, Bradley N. Reames, Jean L. Grem, Lyudmyla Berim, James C. Padussis, Sukhwinder Kaur, Sushil Kumar, Moorthy P. Ponnusamy, Maneesh Jain, Chi Lin, Surinder K. Batra

Journal Articles: Biochemistry & Molecular Biology

BACKGROUND: Radiation therapy (RT) has a suboptimal effect in patients with pancreatic ductal adenocarcinoma (PDAC) due to intrinsic and acquired radioresistance (RR). Comprehensive bioinformatics and microarray analysis revealed that cholesterol biosynthesis (CBS) is involved in the RR of PDAC. We now tested the inhibition of the CBS pathway enzyme, farnesyl diphosphate synthase (FDPS), by zoledronic acid (Zol) to enhance radiation and activate immune cells.

METHODS: We investigated the role of FDPS in PDAC RR using the following methods: in vitro cell-based assay, immunohistochemistry, immunofluorescence, immunoblot, cell-based cholesterol assay, RNA sequencing, tumouroids (KPC-murine and PDAC patient-derived), orthotopic models, and PDAC patient's …

Differential Gene Expression-Based Connectivity Mapping Identified Novel Drug Candidate And Improved Temozolomide Efficacy For Glioblastoma, Raghupathy Vengoji, Pranita Atri, Muzafar A. Macha, Parthasarathy Seshacharyulu, Naveenkumar Perumal, Kavita Mallya, Yutong Liu, Lynette M. Smith, Satyanarayana Rachagani, Sidharth Mahapatra, Moorthy P. Ponnusamy, Maneesh Jain, Surinder K. Batra, Nicole Shonka

Journal Articles: Biochemistry & Molecular Biology

BACKGROUND: Glioblastoma (GBM) has a devastating median survival of only one year. Treatment includes resection, radiation therapy, and temozolomide (TMZ); however, the latter increased median survival by only 2.5 months in the pivotal study. A desperate need remains to find an effective treatment.

METHODS: We used the Connectivity Map (CMap) bioinformatic tool to identify candidates for repurposing based on GBM's specific genetic profile. CMap identified histone deacetylase (HDAC) inhibitors as top candidates. In addition, Gene Expression Profiling Interactive Analysis (GEPIA) identified HDAC1 and HDAC2 as the most upregulated and HDAC11 as the most downregulated HDACs. We selected PCI-24781/abexinostat due to …

The Healers Issue (2021), University Of Montana--Missoula. School Of Journalism

Byline

Taking the Reins: Providing therapeutic horseback riding to Montanans in need -- More than Superstition: A haunted prison fosters connection during COVID-19 -- Public Health: Local healers leave after divisive legislative session -- Misrepresented and Misunderstood: Why media needs to listen to autistics -- Confronting the Past: Recovering from Native American boarding school trauma -- Welcoming Them Home: The return of native species is healing the land of the Aaniiih and Nakoda -- No Place to Stay: The pandemic is pushing people into Montana - and others out -- They didn't bring any houses with them -- As Missoula affordable …

Mitochondrial Aspects Of Neuronal Pathology In Triple-Transgenic Alzheimer’S Disease Mice, John Zachary Cavendish

Graduate Theses, Dissertations, and Problem Reports (ETD)

Alzheimer’s disease (AD) is a fatal, progressive neurodegenerative disease afflicting millions of people in the United States alone and is the only one of the top leading causes of morbidity and mortality with no effective disease-modifying therapies. It is the most common form of dementia, affecting one in three people over the age of 85. While the hallmarks of the disease include accumulation of beta-amyloid-based extracellular plaques and hyperphosphorylated tau-based intracellular neurofibrillary tangles, treatment strategies centered on removing or mitigating these components of AD have all failed in humans. Mitochondrial dysfunction has been increasingly recognized as an early and consistent …

“Don't Give Me Bullshit”: Constructing A Framework Of Response To Fake News, Genevieve Garcia De Mueller, Randall W. Monty

Writing and Language Studies Faculty Publications

No abstract provided.