Digital Commons Network^™

Recovery Of Altered Diabetic Myofibroblast Heterogeneity And Gene Expression Associated With Cd301b+ Macrophages, Maryellen R. Haas, Darlene V. Nguyen, Brett A. Shook

Biochemistry and Molecular Medicine Faculty Publications

No abstract provided.

Analysis Of Hendra Virus Fusion Protein N-Terminal Transmembrane Residues, Chelsea T. Barrett, Hadley E. Neal, Kearstin Edmonds, J. Lizbeth Reyes Zamora, Carole L. Moncman, Andreea Popa, Everett Clinton Smith, Stacy R. Webb, Rebecca Ellis Dutch

Molecular and Cellular Biochemistry Faculty Publications

Hendra virus (HeV) is a zoonotic enveloped member of the family Paramyoxviridae. To successfully infect a host cell, HeV utilizes two surface glycoproteins: the attachment (G) protein to bind, and the trimeric fusion (F) protein to merge the viral envelope with the membrane of the host cell. The transmembrane (TM) region of HeV F has been shown to have roles in F protein stability and the overall trimeric association of F. Previously, alanine scanning mutagenesis has been performed on the C-terminal end of the protein, revealing the importance of β-branched residues in this region. Additionally, residues S490 and Y498 have …

The Aesthetic Legacy Of Evolution: The History Of The Arts As A Window Into Human Nature, Aaron Kozbelt

Publications and Research

No abstract provided.

High-Resolution Late Devonian Magnetostratigraphy From The Canning Basin, Western Australia: A Re-Evaluation, Theodore Green, Sarah P. Slotznick, Plinio Jaqueto, Timothy D. Raub, Eric Tohver, Ted E. Playton, Peter W. Haines, Joseph L. Kirschvink, Roger M. Hocking, Paul Montgomery

Dartmouth Scholarship

Late Devonian time was a period of rapid upheaval in the Earth system, including climate change, sea level changes, widespread ocean anoxia, and the Frasnian-Famennian mass extinction; the cause(s) of these changes remain(s) uncertain. The Lennard Shelf of the Canning Basin in Western Australia contains carbonate reef sections spanning much of the Late Devonian Epoch and has been sampled for paleomagnetic analysis with studies by Hansma and colleagues in 2015 and Playton and colleagues in 2016. However, previous paleomagnetic directions were scattered and their use for magnetostratigraphy has been questioned. Here, rock magnetic data and magnetostratigraphy for a late Devonian …

Punctuated Evolution In The Learned Songs Of African Sunbirds, Jay P. Mcentee, Gleb Zhelezov, Chacha Werema, Nadje Najar, Joshua V. Peñalba, Elia Mulungu, Maneno Mbilinyi, Sylvester Karimi, Lyubov Chumakova, For Complete List Of Authors, See Publisher's Website.

College of Natural and Applied Sciences

Learned traits are thought to be subject to different evolutionary dynamics than other phenotypes, but their evolutionary tempo and mode has received little attention. Learned bird song has been thought to be subject to rapid and constant evolution. However, we know little about the evolutionary modes of learned song divergence over long timescales. Here, we provide evidence that aspects of the territorial songs of Eastern Afromontane sky island sunbirds evolve in a punctuated fashion, with periods of stasis of the order of hundreds of thousands of years or more, broken up by evolutionary pulses. Stasis in learned songs is inconsistent …

Promoter Considerations In The Design Of Lentiviral Vectors For Use In Treating Lysosomal Storage Diseases, Estera Rintz, Takashi Higuchi, Hiroshi Kobayashi, Deni S Galileo, Grzegorz Wegrzyn, Shunji Tomatsu

Department of Pediatrics Faculty Papers

More than 50 lysosomal storage diseases (LSDs) are associated with lysosomal dysfunctions with the frequency of 1:5,000 live births. As a result of missing enzyme activity, the lysosome dysfunction accumulates undegraded or partially degraded molecules, affecting the entire body. Most of them are life-threatening diseases where patients could die within the first or second decade of life. Approximately 20 LSDs have the approved treatments, which do not provide the cure for the disorder. Therefore, the delivery of missing genes through gene therapy is a promising approach for LSDs. Over the years, ex vivo lentiviral-mediated gene therapy for LSDs has been …

Nuanced Networks: How Social Relationships And Power Influence Participation In Private Lands Conservation Programs, Ellen Loechner

Geography ETDs

Because the majority of land in the Midwestern United States is privately owned, the responsibility for creating and maintaining space for wildlife conservation falls upon private landowners. Numerous state and federal agencies and non-governmental organizations (NGOs) host private lands conservation programs that offer landowners financial and technical support to complete conservation projects on their property (Echols, Front, and Cummins 2019). While the individual motivations and priorities of a landowner may inform how they use and manage their property, a landowner’s ability to connect with the agricultural and conservation communities may determine if they have the opportunity to participate in these …

Optimizing Yield And Quality Of Orchardgrass Pasture In Temperate Silvipastoral Systems, P. L. Peri, R. J. Lucas, D. J. Moot, A. C. Varella, D. L. Mcneil

IGC Proceedings (1977-2023)

The objective of this study was to provide grazing management recommendations for a silvipastoral system by determining the effects of shade and nitrogen (N) on the pattern of dry matter accumulation and nutritive value of orchardgrass (Dactylis glomerata) in a subhumid temperate environment. Orchardgrass in open pasture (100% transmittance) and under 10 year old Pinus radiata tree shade (60% transmittance) at 200 stems/ha was used as the main plot and nitrogen (0 and 300 kg N/ha as synthetic urine) was the subplot factor. Dry matter (DM) production of orchardgrass in the first 60-day spring rotation was similar in …

Herbage Characteristics As Affected By The Canopies Of Dominant Trees In A Savanna Of Southern Mozambique, James P. Muir, A. Alage, Inacio C. Maposse

IGC Proceedings (1977-2023)

This study surveyed the species composition, forage yield and forage nitrogen concentration of the herbaceous layer 50, 100 and 200% of the canopy radius from the trunks of many-stemmed false thorn, knob thorn, scented thorn and marula trees in a southern Mozambican savanna. Tree species did not affect herbaceous DM yield or species diversity. Neither direction nor distance from the tree trunk affected DM or specific diversity. Crude protein percentages were 15% higher for legumes and 9% higher for grasses at 50% canopy than at 200% canopy. Grasses under the marulas, the only non-legume tree in the study, had 18% …

Selecting New Brachiaria For Brazilian Pastures, Cacilda B. Do Valle, Valéria P. B. Euclides, Manuel C. M. Macedo, José R. Valério, S. Calixto

IGC Proceedings (1977-2023)

Brazilian beef production relies heavily on cultivated pastures, of which about 80% are planted mainly to two Brachiaria cultivars. The narrowness of diversity associated with reproduction by apomixis of most plants in this genus prompted an intense search for new cultivars amongst recently collected and introduced ecotypes from Africa. This paper reports results for a three-year evaluation of 21 pre-selected ecotypes in two typical Cerrado ecosystems. Plots, replicated four times, were seeded in rows and cut every 6 weeks during the rainy season followed by a cut in the middle and one at the end of the dry season. Significant …

Virus, Violence And (In)Visible Women: #Lockdownmeinlockup And Embodied Resistance During Covid-19, Ishani Mukherjee

Journal of International Women's Studies

Drawing on the #LockDownMeinLockUp visual campaign against domestic violence, this paper conceptually leverages embodied resistance, performed connectivity, and (in)visibility politics to explore how gender, body, power, affect, celebrity, performance, and injustice are framed by digital media in the context of an unprecedented global health crisis. The forms, forces, and incidences of domestic violence (DV) are rooted in local power relations and unique cultural practices and so should their interventions and representations be. Since the March 2020 lockdown, the pandemic worsened the conditions of DV victims in India. Many women were forced to cohabit with abusive partners and families. Data on …

Vicente Pazos, Agent For The Amelia Island Filibusters, 1818, Charles H. Bowman, Jr.

Florida Historical Quarterly

The appearance of a North American squadron under John D. Henley and a land force under James Bankhead at the mouth of the St. Marys River on December 18, 1817, with orders to move against Luis Aury and his establishment on Amelia Island, compelled the filibusters to abandon posthaste their illfated Republic of the Floridas. Aury had occupied the island since September under the flag of Mexico. It was obvious that the North American fighting power was superior to any that Aury could muster and that surrender of the island was inevitable.

Book Reviews, Florida Historical Society

Florida Historical Quarterly

THE EVERGLADES: FROM YESTERDAY TO TOMORROW, by Wyatt Blassingame, reviewed by Thelma Peters; THE NEW FLORIDA ATLAS: PATTERNS OF THE SUNSHINE STATE, by Roland Wood and Edward A. Fernald, reviewed by Robert B. Marcus; WEST GEORGIA COLLEGE STUDIES IN THE SOCIAL SCIENCES, VOLUME XII, GEOGRAPHIC PERSPECTIVES ON SOUTHERN DEVELOPMENT, edited by John C. Upchurch and David C. Weaver, reviewed by Shannon McCune; MONEY AND POLITICS IN AMERICA, 1755-1775: A STUDY IN THE CURRENCY ACT OF 1764 AND THE POLITICAL ECONOMY OF REVOLUTION, by Joseph Albert Ernst, reviewed by Richard B. Sheridan; THE OLD DOMINION AND THE NEW NATION, 1788-1801, by …

The Case Of Tom Tiger's Horse: An Early Foray Into Indian Rights, Harry A. Kersey, Jr.

Florida Historical Quarterly

At a time in our national history when the American Indian’s claim to social and political justice is being vigorously pursued, and dramatically portrayed through mass media coverage of incidents such as the occupation of Alcatraz, disruption at the Bureau of Indian Affairs in Washington, and a “Second Wounded Knee,” it might be well to consider in calmer retrospective one of those little known efforts to secure Indian rights which occurred in Florida at the turn of the century. The participants included an aggrieved Seminole headman of the Cow Creek band and his white friends who displayed an unusual zeal …

Florida Seminoles: 1900-1920, James W. Covington

Florida Historical Quarterly

The Florida Seminoles at the beginning of the twentieth century enjoyed a relatively good life. The more than 500 Indians were able to roam freely throughout a 20,000 square mile area situated in the lower part of the peninsula and lying mostly between the settled portions of the east and west coasts of Florida. Since the total population in this wilderness area including Indians, squatters, hunters, and trappers did not number more than 600 persons, there was room for all concerned. The Seminoles supported themselves by otter, plume, and alligator hunting, and they traded these feathers, hides, and skins for …

Greens, Grist And Guernseys: Development Of The Florida State Agricultural Marketing System, Martin M. Lagodna

Florida Historical Quarterly

The Federal Governments role in aiding farmers is well known; the states’s relationship to agriculture has not been very well chronicled. Florida, for example, was slow in responding to federal stimuli in the early twentieth century, but once underway the state developed innovative programs to help farmers with their economic problems. Agriculture specialists believed that distribution of goods rather than production was the major problem. In the American capitalist system the markets functioned as the distributive agencies. The economists focused their attention on agricultural marketing and importuned government to assist with this endeavor.

When A Minority Becomes The Majority: Blacks In Jacksonville Politics, 1887-1907, Edward N. Akin

Florida Historical Quarterly

With the end of Reconstruction in 1876, the national Republican party abandoned the blacks of the South to state governments controlled by native southern whites. This traditional textbook interpretation of the plight of blacks in the Bourbon South rested on two implicit assumptions: the black was dependent on national Republicanism for protection; and, with the end of this protective system, blacks ceased to be a viable independent political element.1 When blacks did vote during the Bourbon era, they were pictured as sheep being led by conservative whites. An example of this voting behavior in an urban setting is recounted in …

Book Reviews, Florida Historical Society

Florida Historical Quarterly

THE SEGREGATION FACTOR IN THE FLORIDA DEMOCRATIC GUBERNATORIAL PRIMARY OF 1956, by Helen L. Jacobstein, reviewed by Joseph A. Tomberlin; MINING IN THE NEW WORLD, by Carlos Prieto, reviewed by Luis Rafael Arana; THE PRICE OF LOYALTY: TORY WRITINGS FROM THE REVOLUTIONARY ERA, edited by Catherine S. Crary, reviewed by Geraldine M. Meroney; THE GENET MISSION, by Harry Ammon, reviewed by George C. Rogers, Jr.; THE PAPERS OF JOHN C. CALHOUN: VOLUME VII, 1822-1823, edited by W. Edwin Hemphill, reviewed by Thomas P. Govan; MR. POLK’S WAR: AMERICAN OPPOSITION AND DISSENT, 1846-1848, by John H. Schroeder, reviewed by Gerald M. …

Tallahassee Through The Storebooks: Era Of Radical Reconstruction, 1867-1877, Clifton Paisley

Florida Historical Quarterly

Leon was the largest and richest county in Florida at the outbreak of the Civil War. Its population numbered 12,343, and its property was assessed at $8,843,095 in 1860. It led the state in agriculture; its farms were valued at $2,482,211, and during the crop year 1859 they produced 16,686 bales of cotton, 421,654 bushels of corn, and 136,038 bushels of sweet potatoes. It ranked third in manufacturing. Twenty-six establishments in 1859 employed 239 male and seven female workers and produced products worth $261,200. The county, like the rest of Florida and the South, suffered grievous economic losses during the …

Florida History Research In Progress, Florida Historical Society

Florida Historical Quarterly

This list shows the amount and variety of Florida history research and writing currently underway and as reported to the Florida Historical Quarterly. Doctoral dissertations and masters theses completed in 1973 are included. Research in Florida history, sociology, authropology, political science, archeology, geography, and urban studies is included.

Book Reviews, Florida Historical Society

Florida Historical Quarterly

SLAVERY AND PLANTATION GROWTH IN ANTEBELLUM FLORIDA, 1821-1860, by Julia Floyd Smith, reviewed by Clifton Paisley; JOURNEY THROUGH THE OLD EVERGLADES: THE LOG OF THE MINNEHAHA, edited by Pat Dodson, reviewed by Charlton W. Tebeau; EVERGLADES COUNTRY: A QUESTION OF LIFE OR DEATH, by Patricia Lauber, reviewed by Thelma Peters; PALMETTO RAMBLER, by Walter R. Hellier, reviewed by Eugene Lyon; FRANCISCO PAREJA’S 1613 CONFESSIONARIO: A DOCUMENTARY SOURCE FOR TIMUCUAN ETHNOGRAPHY, edited by Jerald T. Milanich and William C. Sturtevant, reviewed by Charles Hudson; SHIPPING, MARITIME TRADE AND THE ECONOMIC DEVELOPMENT OF COLONIAL NORTH AMERICA, by James F. Shepherd and Gary …

East Florida In 1834: Letters Of Dr. John Durkee, W. Stanley Hoole

Florida Historical Quarterly

In the summer of 1833 Dr. John Durkee, for more than ten years a practicing physician in Meredith Bridge (now a part of Laconia), New Hampshire, traveled to East Florida for the benefit of his health.1 Settling in Jacksonville, a village of fewer than 250 people and about twenty houses and stores, he soon recuperated sufficiently to lead an active life.2 He rode horseback into the hinterland of Duval County, hunted, fished, and because of his scientific background interested himself primarily in such subjects as alligators, snakes, deer, birds, trees, cattle, soils, and Indian archeology. Meantime, he kept abreast of …

Book Reviews, Florida Historical Society

Florida Historical Quarterly

RIVER OF THE GOLDEN IBIS, by Gloria Jahoda, reviewed by Frank G. Slaughter; TALES OF OLD BREVARD, by Georgiana Kjerulff, reviewed by Ernest Lyons; HUNTED LIKE A WOLF: THE STORY OF THE SEMINOLE WAR, by Milton Meltzer, reviewed by James W. Covington; FLORIDA PROMOTERS: THE MEN WHO MADE IT BIG, by Charles E. Harner, reviewed by Thomas S. Graham; SUGAR AND SLAVES: THE RISE OF THE PLANTER CLASS IN THE ENGLISH WEST INDIES, 1624-1713, by Richard S. Dunn, reviewed by Robert R. Rea; THE PAPERS OF HENRY LAURENS, VOLUME THREE: JAN. 1, 1759-AUG. 31, 1763, edited by Philip M. Hamer …

Book Reviews, Florida Historical Society

Florida Historical Quarterly

FLORIDA, LAND OF IMAGES, by Nixon Smiley, reviewed by William M. Goza; PAPA: HEMINGWAY IN KEY WEST, by James McLendon, reviewed by Kathryn Hall Proby; FRANCIS DRAKE, PRIVATEER CONTEMPORARY NARRATIVES AND DOCUMENTS, edited by John Hampden, reviewed by Paul E. Hoffman; BLAZE OF GLORY: THE FIGHT FOR NEW ORLEANS, 1814-1815, by Samuel Carter, III, reviewed by Frank L. Owsley, Jr.; THE MALLORYS OF MYSTIC: SIX GENERATIONS IN AMERICAN MARITIME ENTERPRISE, by James P. Baughman, reviewed by Edward A. Mueller; DANIEL LEE, AGRICULTURIST: HIS LIFE NORTH AND SOUTH, by E. Merton Coulter, reviewed by James C. Bonner; BOOKER T. WASHINGTON: THE …

Economic Basis Of The Seventeenth-Century Florida Missions, Robert Allen Matter

Florida Historical Quarterly

Many Americans are familiar with the chain of Franciscan missions in Spanish California. Less well-known is the significant Franciscan mission system that flourished among the Florida Indians more than a century before the friars founded their first Upper California mission at San Diego in 1769. The Franciscans began their program in Florida in the late sixteenth century, fter the collapse in martyrdom of a relatively weak, five-year Jesuit effort. Within a hundred years the friars had forged their mission chains from the presidio at St. Augustine some 200 miles north along the Florida and Georgia coasts, to the vicinity of …

A Light Unseen: The History Of Catholic Legal Education In The United States: A Response To Our Colleagues And Critics, John M. Breen, Lee J. Strang

Journal of Catholic Legal Studies

(Excerpt)

We are enormously grateful to the Journal of Catholic Legal Studies for hosting the conference on February 14, 2020, dedicated to a review of our book manuscript, A Light Unseen: The History of Catholic Legal Education in the United States, and for publishing the papers of the conference participants. We are also grateful for the opportunity to offer some reply in the pages of the Journal. A Light Unseen sets forth a comprehensive history of the book’s subject matter. The book describes the purposes for which Catholic law schools were founded, the schools maturation and success in …

A Comparison Of Treatment Options For Carpal Boss: A Critically Appraised Topic, Megan M. Collins, Matthew J. Rivera

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Context: Carpal bossing is a bony growth or mass that typically occurs at the 2^nd or 3^rd carpometacarpal joint. Carpal bossing is often overlooked placing the patient at an increased risk for pain or injury, such as osteoarthritis or inflammatory joint disease if left untreated. Individuals such as combat sport athletes who experience repetitive trauma to this area are at a high risk to develop carpal bossing. The literature suggests conservative or surgical interventions to manage symptoms. The goal of this systematic review is to synthesize the current literature for clinical knowledge and intervention outcomes for carpal bossing. …

Differentiation Of Fetal Hematopoietic Stem Cells Requires Arid4b To Restrict Autocrine Kitlg/Kit-Src Signaling., In-Chi Young, Bogang Wu, Jaclyn Andricovich, Sung-Ting Chuang, Rong Li, Alexandros Tzatsos, Ray-Chang Wu, Mei-Yi Wu

Anatomy and Regenerative Biology Faculty Publications

No abstract provided.

Soil Bacteria In Urban Community Gardens Have The Potential To Disseminate Antimicrobial Resistance Through Horizontal Gene Transfer, Abdullah Ibn Mafiz, Yingshu He, Wei Zhang, Yifan Zhang

Agricultural and Environmental Sciences Faculty Research

Fifteen soil and 45 vegetable samples from Detroit community gardens were analyzed for potential antimicrobial resistance contamination. Soil bacteria were isolated and tested by antimicrobial susceptibility profiling, horizontal gene transfer, and whole-genome sequencing. High-throughput 16S rRNA sequencing analysis was conducted on collected soil samples to determine the total bacterial composition. Of 226 bacterial isolates recovered, 54 were from soil and 172 from vegetables. A high minimal inhibitory concentration (MIC) was defined as the MIC greater than or equal to the resistance breakpoint of Escherichia coli for Gram-negative bacteria or Staphylococcus aureus for Gram-positive bacteria. The high MIC was observed in …

Insulin-Like Growth Factor-1 Differentially Modulates Glutamate-Induced Toxicity And Stress In Cells Of The Neurogliovascular Unit, Cellas A. Hayes, Brandon G. Ashmore, Akshaya Vijayasankar, Jessica P. Marshall

Faculty and Student Publications

The age-related reduction in circulating levels of insulin-like growth factor-1 (IGF-1) is associated with increased risk of stroke and neurodegenerative diseases in advanced age. Numerous reports highlight behavioral and physiological deficits in blood-brain barrier function and neurovascular communication when IGF-1 levels are low. Administration of exogenous IGF-1 reduces the extent of tissue damage and sensorimotor deficits in animal models of ischemic stroke, highlighting the critical role of IGF-1 as a regulator of neurovascular health. The beneficial effects of IGF-1 in the nervous system are often attributed to direct actions on neurons; however, glial cells and the cerebrovasculature are also modulated …