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2021

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Chlorine Decay And Pathogen Cross Contamination Dynamics In Fresh Produce Washing Process, Mohammadreza Dehghan Abnavi Jan 2021

Chlorine Decay And Pathogen Cross Contamination Dynamics In Fresh Produce Washing Process, Mohammadreza Dehghan Abnavi

ETD Archive

In this study, we developed a comprehensive mathematical model to predict the free chlorine (FC) concentration and bacterial cross-contamination during produce wash processes. A second-order chemical reaction model for FC decay which utilizes a proportion of chemical oxygen demand (COD) as an indicator of organic content in the wash water was employed, yielding an apparent reaction rate of 9.45 ± 0.22 x 10-4 ^M-1.min-1. Using a proportion of successive changes in COD in the wash water due to produce washing, typically ranging from 6 to 11% across produce types, the model was able to consistently predict experimental FC levels, however, …


Is Hearing Loss Over-Diagnosed Due To Impaired Cognition In Elderly Patients?, Emilee A. Witt Jan 2021

Is Hearing Loss Over-Diagnosed Due To Impaired Cognition In Elderly Patients?, Emilee A. Witt

ETD Archive

The prevalence of hearing loss due to old age is rapidly growing amongst the elderly population impacting over 450 million people worldwide making it the third most chronic disease (Lohler et al., 2019). While highly prevalent, hearing loss still remains one of the least studied factors, yet it has one of the greatest impacts on public health as 67% of adults age 70 and up have a hearing loss that impedes daily communication (Lin & Albert, 2014). Research has found a connection between hearing loss and cognitive deficits. People with hearing loss experience cognitive decline 30% to 40% faster than …


University Of Richmond Magazine, Winter 2021 Jan 2021

University Of Richmond Magazine, Winter 2021

University of Richmond Magazine

The University of Richmond's Alumni Magazine was first published as The Alumni Bulletin in 1936 and continues to this day as the University of Richmond Magazine.


Fish & Wildlife News: Winter 2021, Matt Trott Jan 2021

Fish & Wildlife News: Winter 2021, Matt Trott

Fish and Wildlife News

No abstract provided.


A Civil Society: The Public Space Of Freemason Women In France, 1744–1944, James Smith Allen Jan 2021

A Civil Society: The Public Space Of Freemason Women In France, 1744–1944, James Smith Allen

University of Nebraska Press: Sample Books and Chapters

A Civil Society explores the struggle to initiate women as full participants in the masonic brotherhood that shared in the rise of France’s civil society and its “civic morality” on behalf of women’s rights. As a vital component of the third sector during France’s modernization, freemasonry empowered women in complex social networks, contributing to a more liberal republic, a more open society, and a more engaged public culture.

James Smith Allen shows that although women initially met with stiff resistance, their induction into the brotherhood was a significant step in the development of French civil society, including the promotion of …


Symposium: The Roberts Court And Free Speech: Transcript, Michael Cahill, Joel Gora, Geoffrey Stone Jan 2021

Symposium: The Roberts Court And Free Speech: Transcript, Michael Cahill, Joel Gora, Geoffrey Stone

Articles

No abstract provided.


Implications Of Historical And Contemporary Processes On Genetic Differentiation Of A Declining Boreal Songbird: The Rusty Blackbird, R. E. Wilson, S. M. Matsuoka, L. L. Powell, J. A. Johnson, D. W. Demarest, D. Stralberg, S. Sonsthagen Jan 2021

Implications Of Historical And Contemporary Processes On Genetic Differentiation Of A Declining Boreal Songbird: The Rusty Blackbird, R. E. Wilson, S. M. Matsuoka, L. L. Powell, J. A. Johnson, D. W. Demarest, D. Stralberg, S. Sonsthagen

School of Natural Resources: Faculty Publications

No abstract provided.


North Atlantic Right Whales: Common Misconceptions Jan 2021

North Atlantic Right Whales: Common Misconceptions

United States Marine Mammal Commission

No abstract provided.


Crippling Rapid Evolution Of Metastasis And Drug Resistance In A549 Non-Small Cell Lung Cancer Cells With The Clinically Relevant Hsp90 Inhibitor Auy922, Nickolas Anthony Bacon Jan 2021

Crippling Rapid Evolution Of Metastasis And Drug Resistance In A549 Non-Small Cell Lung Cancer Cells With The Clinically Relevant Hsp90 Inhibitor Auy922, Nickolas Anthony Bacon

Theses, Dissertations and Capstones

The ability for species to evolve new features in response to changing circumstances in order to survive and propagate is a ubiquitous observation on both the macroscopic and microscopic levels of living systems. It should be no surprise, then, that diseases such as cancer utilize their own forms of adaptation to perpetuate themselves when exposed to external threats. Indeed, concepts drawn from Darwinian evolution are now widely accepted to help explain certain aspects of carcinogenesis and malignant progression, the sum of which have come to be known as the theory of tumor evolution. Since metastasis and drug resistance are features …


No. 48: Covid-19 And Emergency Food Security Policies In Urban China, Taiyang Zhong, Jonathan Crush, Zhenzhong Si, Steffanie Scott Jan 2021

No. 48: Covid-19 And Emergency Food Security Policies In Urban China, Taiyang Zhong, Jonathan Crush, Zhenzhong Si, Steffanie Scott

Hungry Cities Partnership

The COVID-19 pandemic has continued to spread worldwide, threatening people’s health as well as their food security. Yet, empirical research investigating its impacts on food security is scant. Limited attention has been paid to the local food security management implications of an infectious disease pandemic. To narrow these gaps, this study investigated the development of emergency food policies in Wuhan and Nanjing in China and households’ food security, based on a combination of online surveys of household food security and policy document analysis. This study shows that COVID-19 and associated quarantine measures caused many households to experience food insecurity. There …


Tagtools: Software Supporting Biologging Research, Sam Fynewever, Racheal Tejevbo, Stacy L. De Ruiter Jan 2021

Tagtools: Software Supporting Biologging Research, Sam Fynewever, Racheal Tejevbo, Stacy L. De Ruiter

Summer Research

Observing animals in obscure habitats has long posed a challenge in biology. Biologging addresses this broad problem, obtaining data about animals like their acceleration, GPS position, etc. using electronic tags. Data from tags can lead to important knowledge of animal behavior, as DeRuiter et al. (2013) have shown1 . However, data is often shared raw, causing inconsistencies. This project maintains TagTools, software addressing this specific problem. TagToolsfunctions (in Matlab, Octave & R) calibrate data and help analyze behavior. TagTools software is traditionally taught at in-person workshops. Our old documents (practicals) were hosted online, but had bugs & were very long, …


Using Mesa To Test Our Theory Of Contact Binary Star Evolution, Lauren Henderson, Jenn Lau, Larry A. Molnar Jan 2021

Using Mesa To Test Our Theory Of Contact Binary Star Evolution, Lauren Henderson, Jenn Lau, Larry A. Molnar

Summer Research

A contact binary star system consists of two stars orbiting each other so closely that they share a common atmosphere. Nearly 1% of stars like our sun are contact binaries, yet there is not a comprehensive model of their lives. Our goal is to understand the formation, life, and explosive demise of these objects. This summer we did the first comprehensive calculations of contact binary lifetimes from when they first come into contact until they reach instability.


Environmental Contaminants And Bacterial Infection During Pregnancy: Pilot Study Of Pregnant Murine Co-Exposure To Trichloroethylene (Tce) And Group B Streptococcus (Gbs), Eleanor Scheeres, Emily Schellenboom, Sean Harris, Erica Boldenow Jan 2021

Environmental Contaminants And Bacterial Infection During Pregnancy: Pilot Study Of Pregnant Murine Co-Exposure To Trichloroethylene (Tce) And Group B Streptococcus (Gbs), Eleanor Scheeres, Emily Schellenboom, Sean Harris, Erica Boldenow

Summer Research

  • TCE is a volatile organic solvent used in industrial processes and a known human carcinogen.
  • GBS is a common bacteria in the vaginal flora but can lead to complications such as preterm birth during pregnancy.
  • Co-treatment (GBS+DCVC) in placental membranes lead to inhibition of pathogen stimulated cytokine secretion
  • We hypothesized that along with cytokine secretion, GBS+DCVC co-exposure would have impacts on MMP-9 (a protein involved in gestational membrane degradation) 4 and prostaglandin E2 (a hormone involved in cervical ripening and labor induction) 5, two important proteins in pregnancy and labor


Physiology Of Ischyrobacter In Cephalotes Guts, Yangzhou Su, John T. Wertz Jan 2021

Physiology Of Ischyrobacter In Cephalotes Guts, Yangzhou Su, John T. Wertz

Summer Research

Nitrogen is an essential element for living organisms. For herbivorous ants like Cephalotes (Turtle ants), obtaining sufficient nitrogen is difficult. Previous studies have shown that the diet of turtle ants is nitrogen-limited. Hence they rely on bacterial gut symbionts to provision nitrogen through uric acid recycling. Metagenomic studies suggest the nitrogen recycling process involves multiple symbionts that together can degrade uric acid and produce amino acids. Of the symbionts in the ant gut, the recently cultured Ischyrobacter davidsoniae st. CV33 is an abundant member of the gut community that can degrade uric acid. What is not known is if this …


Nutech Ventures Annual Report 2020-2021 Jan 2021

Nutech Ventures Annual Report 2020-2021

NUtech Ventures: Publications

NUTech Ventures annual report 2020-2021.


Visualizing Women: Teaching Modern Images And Medieval Texts About Pre-Modern Women, Esther Liberman Cuenca Jan 2021

Visualizing Women: Teaching Modern Images And Medieval Texts About Pre-Modern Women, Esther Liberman Cuenca

Quidditas

This paper examines two visual texts for teaching a course called “Saints, Wives and Witches” at the University of Houston-Victoria: Jennifer A. Rea’s graphic novel Perpetua’s Journey (Oxford, 2018), which illustrates the eponymous North African martyr’s third-century prison diary, and the film Vision: From the Life of Hildegard von Bingen (2009), directed by Margarethe von Trotta, who drew on feminist readings of Hildegard of Bingen’s writings for the purposes of dramatization. The course itself followed a chronology that took students from antiquity to the early modern period and was divided into thematic units that highlighted women’s intersecting identities with regards …


A Devised Ethnodrama: Conscious Voices, Sonia Pasqual Jan 2021

A Devised Ethnodrama: Conscious Voices, Sonia Pasqual

Master of Liberal Studies Theses

Using techniques of storytelling, dance, poems, and monologues in the process of re-enacting life stories, the ensemble display issues that may be impeding society’s growth—discrimination against body image, blackness, females, and LGBTQ individuals. In addition, engagement in storytelling and performance can help the audience increase their cognitive skills, empathy, and ability to live a communal life. This evidence-based practice can transform lives and society. It has the potential of continuing to other faculties and with other departments, such as film, musical, and additional narratives. This specific work could be extended out beyond art and education into populations of any communities …


Combined Responses Of Primary Coral Polyps And Their Algal Endosymbionts To Decreasing Seawater Ph, Federica Scucchia, Assaf Malik, Paul Zaslansky, Hollie M. Putnam, Tali Mass Jan 2021

Combined Responses Of Primary Coral Polyps And Their Algal Endosymbionts To Decreasing Seawater Ph, Federica Scucchia, Assaf Malik, Paul Zaslansky, Hollie M. Putnam, Tali Mass

Biological Sciences Faculty Publications

With coral reefs declining globally, resilience of these ecosystems hinges on successful coral recruitment. However, knowledge of the acclimatory and/or adaptive potential in response to environmental challenges such as ocean acidification (OA) in earliest life stages is limited. Our combination of physiological measurements, microscopy, computed tomography techniques and gene expression analysis allowed us to thoroughly elucidate the mechanisms underlying the response of early-life stages of corals, together with their algal partners, to the projected decline in oceanic pH. We observed extensive physiological, morphological and transcriptional changes in surviving recruits, and the transition to a less-skeleton/more-tissue phenotype. We found that decreased …


Hepatotoxicity Reports In The Fda Adverse Event Reporting System Database: A Comparison Of Drugs That Cause Injury Via Mitochondrial Or Other Mechanisms, Payal Rana, D. Aleo, Xuerong Wen, Stephen Jon Kogut Jan 2021

Hepatotoxicity Reports In The Fda Adverse Event Reporting System Database: A Comparison Of Drugs That Cause Injury Via Mitochondrial Or Other Mechanisms, Payal Rana, D. Aleo, Xuerong Wen, Stephen Jon Kogut

Pharmacy Practice and Clinical Research Faculty Publications

Drug-induced liver injury (DILI) is a leading reason for preclinical safety attrition and post-market drug withdrawals. Drug-induced mitochondrial toxicity has been shown to play an essential role in various forms of DILI, especially in idiosyncratic liver injury. This study examined liver injury reports submitted to the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) for drugs associated with hepatotoxicity via mitochondrial mechanisms compared with non-mitochondrial mechanisms of toxicity. The frequency of hepatotoxicity was determined at a group level and individual drug level. A reporting odds ratio (ROR) was calculated as the measure of effect. Between the two DILI …


Adjuvantation Of Influenza Vaccines To Induce Cross-Protective Immunity, Zhoufan Li, Yiwen Zhao, Yibo Li, Xinyuan Chen Jan 2021

Adjuvantation Of Influenza Vaccines To Induce Cross-Protective Immunity, Zhoufan Li, Yiwen Zhao, Yibo Li, Xinyuan Chen

Biomedical and Pharmaceutical Sciences Faculty Publications

Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of hemagglutinin and lack cross-protection. Vaccine adjuvants have been approved to enhance seasonal influenza vaccine efficacy in the elderly and spare influenza vaccine doses. Clinical studies found that MF59 and AS03-adjuvanted influenza vaccines could induce cross-protective immunity against non-vaccine viral strains. In addition to MF59 and AS03 adjuvants, experimental adjuvants, such as Toll-like receptor agonists, saponin-based adjuvants, cholera toxin and heat-labile enterotoxin-based mucosal adjuvants, and physical adjuvants, …


Inulin-Containing Fructo-Oligosaccharides And Anxiety Scores In College Students, Spencer Herkes Jan 2021

Inulin-Containing Fructo-Oligosaccharides And Anxiety Scores In College Students, Spencer Herkes

Graduate Research Theses & Dissertations

The purpose of this study was to determine the effects of inulin, in the form of fructo-oligosaccharides (FOS), on anxiety symptoms in college students. With a prevalence of 40 million adults in the United States, or 18.1% of the population, anxiety is the most common mental illness in the United States. Previous studies have viewed gut microbiota and its potential link to anxiety both in humans and in mice. However, no previous studies viewed college students. Thirteen subjects were assigned to receive either 4.9 g per day of inulin as a treatment (TX) or no supplement as a control (CON) …


Limiting Iron Acquisition Of E. Coli With Anti-Tonb1 And Antitonb2​, Jose Diaz, Ryan Luib, Seethal Doki Jan 2021

Limiting Iron Acquisition Of E. Coli With Anti-Tonb1 And Antitonb2​, Jose Diaz, Ryan Luib, Seethal Doki

Protein Modeling Reports

The bacteria E Coli infect approximately 200,000 individuals in the United States and can lead to critical illnesses. The transfer of iron from the bloodstream to bacteria is one of the main requirements for the survival. One of the mechanisms to obtain iron by use of siderophores and the protein FhuA was investigated. Undergraduate students grouped into teams to each explain a unique molecular story- modeled in Jmol/Pymol and demonstrated through a poster and PowerPoint. Using the PDB file, 2GRX, a drug to inhibit the TonB-Ton Box interaction which provides the FhuA iron mechanism energy to operate was researched. A …


Cardio-Renal Mechanisms Of Fructose-Induced Salt-Sensitive Hypertension, Peter Eric Levanovich Jan 2021

Cardio-Renal Mechanisms Of Fructose-Induced Salt-Sensitive Hypertension, Peter Eric Levanovich

Wayne State University Dissertations

Dietary consumption of fructose facilitates increased intestinal fluid absorption and renal sodium reabsorption, thereby increasing fluid retention. The net result of this is a sustained increased in extracellular fluid volume that leads to states of hypervolemia and subsequent hypertension. Simultaneously, arterial pressure is being elevated by increased autonomic drive stemming from the sympathetic nervous system and various other endovascular proteins that induce vasoconstriction. Under these conditions, the addition of high dietary sodium promotes hypertension prior to the development of significant metabolic disturbances; the subtlety of which may go unnoticed by patients for prolonged periods. While much is understood regarding the …


The Efficacy Of A Novel Facebook-Based Psychosocial Intervention For Adults With Chronic Pain: A Randomized Clinical Trial, Bethany Danielle Pester Jan 2021

The Efficacy Of A Novel Facebook-Based Psychosocial Intervention For Adults With Chronic Pain: A Randomized Clinical Trial, Bethany Danielle Pester

Wayne State University Dissertations

Social networking-based groups such as Facebook groups have become increasingly popular among people with chronic conditions, and the affordances of such groups make them a promising platform for chronic disease intervention. Yet, there have been few controlled tests of the effects of social networking-based groups. Our team developed a Facebook-based intervention that focuses on enhancing social support by connecting adults with peers who also have chronic pain. Using a randomized controlled clinical trial, we aimed to understand the efficacy of this intervention and to explore whether a professional-led support group leads to greater effects than a support group alone. The …


Pharmaceuticals In The Environment: Health Implications And Environmental Toxicity, Jessica Phillips Jan 2021

Pharmaceuticals In The Environment: Health Implications And Environmental Toxicity, Jessica Phillips

Wayne State University Dissertations

Approximately 2.9 billion prescriptions are written annually in the United States, with a multitude of biochemical actions, with 63151 tons used by food producing animals worldwide and an additional 55-77 million prescriptions written for companion animals. With increasing prescription and unknown toxicologic effects of many of these chemicals, zebrafish (danio rerio), an NIH approved human model, were used to model potentially health effects. Significant abnormalities were seen with extended duration metformin exposure from 4 hours post fertilization up to 5 days post fertilization, although short term metformin exposure for 24 hours at 4-5 days post fertilization did not lead to …


Association Of Gestational Opioid Exposure And Risk Of Major And Minor Congenital Malformations, Xuerong Wen, Nicholas Belviso, Emily Murray, Adam K. Lewkowitz, Kristina E. Ward, Kimford J. Meador Jan 2021

Association Of Gestational Opioid Exposure And Risk Of Major And Minor Congenital Malformations, Xuerong Wen, Nicholas Belviso, Emily Murray, Adam K. Lewkowitz, Kristina E. Ward, Kimford J. Meador

Pharmacy Practice and Clinical Research Faculty Publications

Importance: The rapid increase of opioid-related overdoses and deaths has become a public health concern in the US. Use of prescription opioids in pregnant women has increased; results from teratogenicity studies remain controversial.

Objective: To evaluate the association between maternal prescription opioid use (excluding opioid use disorders) during pregnancy and the incidence of congenital malformations.

Design, Setting, and Participants: This retrospective population-based cohort study evaluated linked Rhode Island Medicaid claims and vital statistics data of live births from January 1, 2008, to December 31, 2016. Data analysis was conducted from May 1, 2019, to May 31, 2020. …


Jesus’ First Visit To The Temple, S. Kent Brown Jan 2021

Jesus’ First Visit To The Temple, S. Kent Brown

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

In this rich and detailed description, S. Kent Brown paints an evocative, historically contextualized account of Jesus Christ’s first visit to the Jerusalem Temple since his infancy, when at age twelve he traveled with his family to attend Passover.


Glad Tidings From Cumorah: Interpreting The Book Of Mormon Through The Eyes Of Someone In Hell, Steve Fotheringham Jan 2021

Glad Tidings From Cumorah: Interpreting The Book Of Mormon Through The Eyes Of Someone In Hell, Steve Fotheringham

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

This article offers evidence that at least some Book of Mormon authors may have understood the potential for post-mortal preaching of the gospel. Indeed, they may have recognized that the future Book of Mormon would be a tool to spread the gospel not only among the living but also among those in the spirit world. Prophecies about the message of the Book of Mormon and the restored gospel being for all mankind may have broader scope than previously recognized, with application on both sides of the veil.


Deprivation Of The Right To Counsel For Federal Pretrial Detainees During The 2019 Novel Coronavirus Pandemic, 54 Uic L. Rev. 659 (2021), Mary Vukovich Jan 2021

Deprivation Of The Right To Counsel For Federal Pretrial Detainees During The 2019 Novel Coronavirus Pandemic, 54 Uic L. Rev. 659 (2021), Mary Vukovich

UIC Law Review

No abstract provided.


Review: Perspective On High-Performing Dairy Cows And Herds, J. H. Britt, R. A. Cushman, C. D. Dechow, H. Dobson, P. Humblot, M. F. Hutjens, G. A. Jones, F. M. Mitloehner, P. L. Ruegg, I. M. Sheldon, J. S. Stevenson Jan 2021

Review: Perspective On High-Performing Dairy Cows And Herds, J. H. Britt, R. A. Cushman, C. D. Dechow, H. Dobson, P. Humblot, M. F. Hutjens, G. A. Jones, F. M. Mitloehner, P. L. Ruegg, I. M. Sheldon, J. S. Stevenson

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Milk and dairy products provide highly sustainable concentrations of essential amino acids and other required nutrients for humans; however, amount of milk currently produced per dairy cow globally is inadequate to meet future needs. Higher performing dairy cows and herds produce more milk with less environmental impact per kg than lower performing cows and herds. In 2018, 15.4% of the world's dairy cows produced 45.4% of the world's dairy cow milk, reflecting the global contribution of high-performing cows and herds. In high-performing herds, genomic evaluations are utilized for multiple trait selection, welfare is monitored by remote sensing, rations are formulated …