Digital Commons Network^™

Rsif Weekly Vol.2 No.2 - Making It To The Phd, Regional Scholarship And Innovation Fund (Rsif)

Rsif Newsletters

No abstract provided.

Daily Digest - Wednesday, January 20, 2021 Covid-19 Updates, University Of Mississippi

COVID-19 Website Archives

Campus Update Daily Digest for Wednesday, January 20, 2021

The Lumberjack, January 20, 2021

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

2021-01-20 Undergraduate Curriculum Committee Meeting Minutes, Morehead State University. Faculty Senate., Undergraduate Curriculum Committee.

Faculty Senate Records

Undergraduate Curriculum Committee meeting minutes for January 20, 2021.

Genetic Approach To Elucidate The Role Of Cyclophilin D In Traumatic Brain Injury Pathology, Ryan D. Readnower, W. Brad Hubbard, Olivia J. Kalimon, James W. Geddes, Patrick G. Sullivan

Spinal Cord and Brain Injury Research Center Faculty Publications

Cyclophilin D (CypD) has been shown to play a critical role in mitochondrial permeability transition pore (mPTP) opening and the subsequent cell death cascade. Studies consistently demonstrate that mitochondrial dysfunction, including mitochondrial calcium overload and mPTP opening, is essential to the pathobiology of cell death after a traumatic brain injury (TBI). CypD inhibitors, such as cyclosporin A (CsA) or NIM811, administered following TBI, are neuroprotective and quell neurological deficits. However, some pharmacological inhibitors of CypD have multiple biological targets and, as such, do not directly implicate a role for CypD in arbitrating cell death after TBI. Here, we reviewed the …

The Association Of Circulating Amylin With Β-Amyloid In Familial Alzheimer's Disease, Han Gia Ly, Nirmal Verma, Savita Sharma, Deepak Kotiya, Sanda Despa, Erin L. Abner, Peter T. Nelson, Gregory A. Jicha, Donna M. Wilcock, Larry B. Goldstein, Rita Guerreiro, José Brás, Angela J. Hanson, Suzanne Craft, Andrew J. Murray, Geert Jan Biessels, Claire Troakes, Henrik Zetterberg, John Hardy, Tammaryn Lashley, Alzheimer’S Disease Exome Sequencing Group, Florin Despa

Pharmacology and Nutritional Sciences Faculty Publications

Introduction

This study assessed the hypothesis that circulating human amylin (amyloid‐forming) cross‐seeds with amyloid beta (Aβ) in early Alzheimer's disease (AD).

Methods

Evidence of amylin‐AD pathology interaction was tested in brains of 31 familial AD mutation carriers and 20 cognitively unaffected individuals, in cerebrospinal fluid (CSF) (98 diseased and 117 control samples) and in genetic databases. For functional testing, we genetically manipulated amylin secretion in APP/PS1 and non‐APP/PS1 rats.

Results

Amylin‐Aβ cross‐seeding was identified in AD brains. High CSF amylin levels were associated with decreased CSF Aβ42 concentrations. AD risk and amylin gene are not correlated. Suppressed amylin secretion protected …

C-Reactive Protein-Based Strategy To Reduce Antibiotic Dosing For The Treatment Of Pneumococcal Infection, Donald N. Ngwa, Sanjay K. Singh, Alok Agrawal

ETSU Faculty Works

C-reactive protein (CRP) is a component of innate immunity. The concentration of CRP in serum increases in microbial infections including Streptococcus pneumoniae infection. Employing a mouse model of pneumococcal infection, it has been shown that passively administered human wild-type CRP protects mice against infection, provided that CRP is injected into mice within two hours of administering pneumococci. Engineered CRP (E-CRP) molecules have been reported recently; unlike wild-type CRP, passively administered E-CRP protected mice against infection even when E-CRP was injected into mice after twelve hours of administering pneumococci. The current study was aimed at comparing the protective capacity of E-CRP …

Environmental Effects Of Stratospheric Ozone Depletion, Uv Radiation, And Interactions With Climate Change: Unep Environmental Effects Assessment Panel, Update 2020, Laura S. Bruckman

Faculty Scholarship

This assessment by the Environmental Effects Assessment Panel (EEAP) of the United Nations Environment Programme (UNEP) provides the latest scientific update since our most recent comprehensive assessment (Photochemical and Photobiological Sciences, 2019, 18, 595–828). The interactive effects between the stratospheric ozone layer, solar ultraviolet (UV) radiation, and climate change are presented within the framework of the Montreal Protocol and the United Nations Sustainable Development Goals. We address how these global environmental changes affect the atmosphere and air quality; human health; terrestrial and aquatic ecosystems; biogeochemical cycles; and materials used in outdoor construction, solar energy technologies, and fabrics. In many cases, …

Experimental Pharmacotherapies In Models Of Alcohol Addiction, Mousumi Akter Sumi

Theses and Dissertations

The USA faces $220 billion economic loss and eighty thousand deaths per year due to alcohol abuse while affecting more than 15 million people, making it the third largest life-style related cause of death. The U.S. FDA has approved four medications namely, disulfiram, acamprosate, oral naltrexone, and injectable long-acting naltrexone. These existing drugs are trashed with side effects, have a low success rate, indicating a demand for new potential drugs. We studied the effects of the CB1 negative allosteric modulator, PSNCBAM-1, and the dopamine D4 receptor antagonist, L-745,870 in mouse models of alcohol addiction. PSNCBAM-1 did not significantly reduce CPP …

Office Of Research, Economic Engagement And Outreach Update, January 20, 2021, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

The Effect Innovation Of Information Technology, Product, Work, And Service Toward Development Performance Academic Business Laboratory In Indonesia, Ilham M, Tanti Handriana, Fendy Suhariadi

Library Philosophy and Practice (e-journal)

This study was conducted to compile a work plan and create an integrated laboratory information system and improve academic services at Uin Sunan Ampel Surabaya based on the implementation of work programs towards a world class university. The purpose of this research activity is to design and implement a system capable of providing work information for each manager of the integration laboratory and maximizing the utilization of the integration laboratory so that the use of the integration laboratory is better and more precise. The results of this research can form an integrated laboratory information system that can optimize the performance …

Forecast Of China’S Economic Growth Rate In 2021 And Policy Suggestions, Xikang Chen, Cuihong Yang, Kunfu Zhu, Huijuan Wang, Xinru Li, Qingyan Jiang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Under the joint impact of the COVID-19 epidemic and the complex international situation, the future direction of China's economic development has attracted much attention. This study systematically analyzes and forecasts the development trend and regularity of China's medium and long-term economic growth rate. It is expected that the medium and long-term economic growth rate of China will show a downward trend in a wave shape. Based on the systematic integrated prediction approach on annual GDP growth proposed by our team, this study reviews China's economic development in 2020 and forecasts China's economic growth rate in 2021. It is expected that …

Establish Integrated Crop-Livestock Production To Promote Ammonia Reduction In Livestock Industry, Hongnan Liu, Yulong Yin

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Get To Know: Bella Gamez, Georgia Southern University

Athletics: News & Publications

• Get to Know: Bella Gamez

Intervention Of Climate‐Smart Practices In Wheat Under Rice‐ Wheat Cropping System In Nepal, Jamma Jaya Gairhe, Mandeep Adhikari, Deepak Ghimire, Arun Kjatri-Chhetri, Dinesh Panday

Department of Agronomy and Horticulture: Faculty Publications

Besides a proper agronomic management followed by Nepalese farmers, wheat (Triticum aestivum L.) production has been severely affected by changing climate. There are many interventions, including climate‐smart practices, to cope with this situation and possibly enhance crop and soil productivity. Field experiments were set up in a randomized complete block design with six treatments (TRT) with four replications in three locations (LOC) during wheat‐growing seasons in Nepal from 2014 to 2016. Treatments included (i) Controlled Practice (CP), (ii) Improved Low (IL), (iii) Improved High (IH), (iv) Climate Smart Agriculture Low (CSAL), (v) Climate Smart Agriculture Medium (CSAM), and (vi) Climate …

The Bg News January 20, 2021, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 20, 2021. Volume 100-Issue 17.

Implications Of Oligomeric Amyloid-Beta (Oaβ42) Signaling Through Α7Β2-Nicotinic Acetylcholine Receptors (Nachrs) On Basal Forebrain Cholinergic Neuronal Intrinsic Excitability And Cognitive Decline, Andrew A George, Jaime M Vieira, Cameron Xavier-Jackson, Michael T Gee, John R Cirrito, Heather A Bimonte-Nelson, Marina R Picciotto, Ronald J Lukas, Paul Whiteaker

2020-Current year OA Pubs

Neuronal and network-level hyperexcitability is commonly associated with increased levels of amyloid-β (Aβ) and contribute to cognitive deficits associated with Alzheimer's disease (AD). However, the mechanistic complexity underlying the selective loss of basal forebrain cholinergic neurons (BFCNs), a well-recognized characteristic of AD, remains poorly understood. In this study, we tested the hypothesis that the oligomeric form of amyloid-β (oAβ

Breeding And Utilization Of Poa Pratensis L. Cv. Daqingshan, Suying Wen

IGC Proceedings (1977-2023)

No abstract provided.

Beef Cattle Performance In A Silvopastoral System Fertilized With N And K, In Brazilian Cerrado, F. S. Bernardino, R. Garcia, J. C. L. Neves, R. G. Tonucci

IGC Proceedings (1977-2023)

No abstract provided.

Evaluation Of Reproductive Phenology And Ecology Of The Eastern Wild Turkey (Meleagris Gallopavo Silvestris) In West-Central Louisiana, Erin E. Ulrey

LSU Master's Theses

Nest predation is the primary source of nest failure, with vegetative conditions at the nest sites considered drivers of reproductive success. Our current understanding of how incubating Eastern wild turkeys (Meleagris gallopavo silvestris, hereafter, wild turkey) use vegetative characteristic relating to specific predators of wild turkey nests is limited. We quantified the occurrence, diversity, and distribution of potential wild turkey nest predator species across Kisatchie National Forest and Peason Ridge WMA in central Louisiana in relation to vegetative conditions located within incubation ranges used by nesting female wild turkeys. We used 210 camera trap sites surveying 5,144 trap nights …

Psu With Electronic Bug Repellent Solution, Hp Inc

Defensive Publications Series

The disclosure below provides a unique solution of a power supply unit (PSU) using an electronic

device emitting ultrasonic sound to repel bugs (small insects, cockroaches, etc.) that may crawl

inside the PSU and caused it to fail by shorting and damaging various components.

As it is impossible to entirely eliminate these small insects in our home and office environment,

some find their way to a PSU of an electronic device causing immediate failure. Product design of

electronic products usually does not include any bug protection features.

Ua12/2/1 College Heights Herald, Vol. 96, No. 14, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Deppen, Laurel. In Loving Memory of Our Friend, Elliott Wells
• Collins, Michael. Quarantine Housing Relocates, Updates Meals
• Deppen, Laurel. The Only Consistent Thing is Change
• Mallon, Sam. Delayed – Maggie Smith
• Bertucci, Leo. WKU Aids in Contact Tracing for Spring 2021
• Murray, Debra. COVID-19 Vaccine
• Kieser, Nick. TOPCARE Focuses on Athletes’ Mental Health
• Toennies, Drew. Lady Toppers to Host Middle Tennessee State University – Basketball
• Gaylord, Kaden. Hilltoppers Poised for Second Sweep – Basketball

Connectivity And Savings Propensity Among Odisha Tribals, P.V. Viswanath

Faculty Working Papers and Articles

Tribal areas are some of the poorest regions of India. An increase in local savings is an important tool in fostering sustainable growth in these areas. This paper uses the results of a survey to examine the factors affecting saving in a rural part of Odisha state populated primarily by tribals. We find that an important determinant of savings propensity is connectivity, which we interpret as a measure of the extent to which individuals feel connected to the broader economy, and an indication of their economic optimism. This interpretation is buttressed by the relationship between savings propensity and variables such …

Treading Water: How Citizens, States, And The Environmental Protection Agency Can Restore Proper Criminal Enforcement Of The Clean Water Act's National Pollutant Discharge Elimination System, Marley Kimelman

Washington Journal of Environmental Law & Policy

Upon the passage of the Clean Water Act (“CWA”) in 1972, primary responsibility for protecting the United States' water quality and preventing water pollution shifted from the states to the Environmental Protection Agency (“EPA”). The program at the heart of the Clean Water Act, the National Pollutant Discharge Elimination System (“NPDES”), requires anyone who discharges pollutants into the waters of the United States to abide by the terms of a permit issued under the program. If a discharge occurs in violation of the permit or without a permit, and prosecutors are able to prove the responsible party acted with ordinary …

The Utah Statesman, January 19, 2021, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Long Non-Coding Rna Meg3 Deficiency Impairs Glucose Homeostasis And Insulin Signaling By Inducing Cellular Senescence Of Hepatic Endothelium In Obesity, Xiao Cheng, Mohamed Sham Shihabudeen Haider Ali, Matthew Moran, Martonio Ponte Viana, Sarah L. Schlichte, Matthew C. Zimmerman, Oleh Khalimonchuk, Mark W. Feinberg, Xinghui Sun

Department of Biochemistry: Faculty Publications

Obesity-induced insulin resistance is a risk factor for diabetes and cardiovascular disease. However, the mechanisms underlying endothelial senescence in obesity, and how it impacts obesity-induced insulin resistance remain incompletely understood. In this study, transcriptome analysis revealed that the long non-coding RNA (lncRNA) Maternally expressed gene 3 (Meg3) is one of the top differentially expressed lncRNAs in the vascular endothelium in diet-induced obese mice. Meg3 knockdown induces cellular senescence of endothelial cells characterized by increased senescence-associated β–galactosidase activity, increased levels of endogenous superoxide, impaired mitochondrial structure and function, and impaired autophagy. Moreover, Meg3 knockdown causes cellular senescence of hepatic endothelium in …

The Prospector, January 19, 2021, Utep Student Publications

The Prospector

Headline: Wecome Back Miners!

Memory-Related Frontal Brainwaves Predict Transition To Mild Cognitive Impairment In Healthy Older Individuals Five Years Before Diagnosis, Yang Jiang, Juan Li, Frederick A. Schmitt, Gregory A. Jicha, Nancy B. Munro, Xiaopeng Zhao, Charles D. Smith, Richard J. Kryscio, Erin L. Abner

Behavioral Science Faculty Publications

BACKGROUND: Early prognosis of high-risk older adults for amnestic mild cognitive impairment (aMCI), using noninvasive and sensitive neuromarkers, is key for early prevention of Alzheimer's disease. We have developed individualized measures in electrophysiological brain signals during working memory that distinguish patients with aMCI from age-matched cognitively intact older individuals.

OBJECTIVE: Here we test longitudinally the prognosis of the baseline neuromarkers for aMCI risk. We hypothesized that the older individuals diagnosed with incident aMCI already have aMCI-like brain signatures years before diagnosis.

METHODS: Electroencephalogram (EEG) and memory performance were recorded during a working memory task at baseline. The individualized baseline neuromarkers, …

Independent And Cumulative Impacts Of Adverse Childhood Experiences On Adolescent Subgroups Of Anxiety And Depression, Isak Kim, Angélica Galván, Nayoung Kim

Counseling Faculty Publications

The purpose of this study is to investigate the independent and cumulative impacts of Adverse Childhood Experiences (ACEs) on the subgroups of anxiety and depression among 12–17 aged adolescents in the U.S. A sample of 21,496 cases was derived from the 2017–2018 National Survey of Children’s Health (NSCH). Four adolescent subgroups were identified depending on their mental health condition: Anxiety-only (7.2%), Depression-only (1.5%), Anxiety-Depression (6.3%), and None (85.0%). All sociodemographic characteristics such as sex, age, race/ethnicity, and family structure had significant associations with the subgroups. Two multinomial logistic regression analyses were conducted to examine the independent and cumulative effects of …

Coxsackievirus B3 Infection Early In Pregnancy Induces Congenital Heart Defects Through Suppression Of Fetal Cardiomyocyte Proliferation, Vipul Sharma, Lisa S Goessling, Anoop K Brar, Chetanchandra S Joshi, Indira U Mysorekar, Pirooz Eghtesady

Open Access Publications

Background Coxsackievirus B (CVB) is the most common cause of viral myocarditis. It targets cardiomyocytes through coxsackie and adenovirus receptor, which is highly expressed in the fetal heart. We hypothesized CVB3 can precipitate congenital heart defects when fetal infection occurs during critical window of gestation. Methods and Results We infected C57Bl/6 pregnant mice with CVB3 during time points in early gestation (embryonic day [E] 5, E7, E9, and E11). We used different viral titers to examine possible dose-response relationship and assessed viral loads in various fetal organs. Provided viral exposure occurred between E7 and E9, we observed characteristic features of …