Digital Commons Network^™

Evaluating The Use Of Marine Protected Areas By Endangered Species: A Habitat Selection Approach, Kelsey E. Roberts, Brian J. Smith, Derek Burkholder, Kristen M. Hart

Marine & Environmental Sciences Faculty Articles

1. Optimizing the design of marine protected area (MPA) networks for the conservation of migratory marine species and their habitats involves a suite of important considerations, such as appropriate scale requirements and the distribution of anthropogenic impacts. Often, a fundamental component of the conservation planning process is delineating areas of high use or high biodiversity within a region of interest.

2. However, basing conservation strategies off merely the number of individuals in an ecosystem is outdated and potentially subject to arbitrary thresholds. To be effective at protecting marine megafauna, MPAs would ideally encompass habitats used by focal species. Through satellite-tracking …

Interactions Of Change In Nutrition After Ai On Plasma Metabolites, Steroid Hormone Production, And Uterine Environment, Taylor N. Andrews, Kaitlin M. Epperson, Jerica J.J. Rich, Saulo Menegatti Zoca, Adalaide C. Kline, Lacey K. Quail, Abigail L. Zezeski, Thomas W. Geary, Julie A. Walker, George A. Perry

SDSU Beef Day 2021 Summary Publication

Objective
The objective was to evaluate the impact of nutritional changes post artificial insemination (AI) on plasma metabolites, steroid hormones, and uterine environment.
Study Description
Beef heifers (n = 43) were randomly assigned to two dietary treatment groups (High = 161.5% or Low = 77.5% of maintenance energy) for 14 d after AI (post-AI). Post-AI dietary treatments continued until uteri were flushed for embryo recovery (d 14 post-AI). Blood samples were collected on d -3, 0 (day of AI), 3, 6, 9, 12, and 14 for analysis of plasma glucose, proteins, non-esterified fatty acids (NEFAs), and cholesterol using colorimetric assays. …

The Genetic Basis Of Inter-Individual Variation In Recovery From Traumatic Brain Injury., Daniel Cortes, Martin Pera

Faculty Research 2021

Traumatic brain injury (TBI) is one of the leading causes of death among young people, and is increasingly prevalent in the aging population. Survivors of TBI face a spectrum of outcomes from short-term non-incapacitating injuries to long-lasting serious and deteriorating sequelae. TBI is a highly complex condition to treat; many variables can account for the observed heterogeneity in patient outcome. The limited success of neuroprotection strategies in the clinic has led to a new emphasis on neurorestorative approaches. In TBI, it is well recognized clinically that patients with similar lesions, age, and health status often display differences in recovery of …

Cognitive Reserve In Model Systems For Mechanistic Discovery: The Importance Of Longitudinal Studies., Joseph A Mcquail, Amy R Dunn, Yaakov Stern, Carol A Barnes, Gerd Kempermann, Peter R Rapp, Catherine C Kaczorowski, Thomas C Foster

Faculty Research 2021

The goal of this review article is to provide a resource for longitudinal studies, using animal models, directed at understanding and modifying the relationship between cognition and brain structure and function throughout life. We propose that forthcoming longitudinal studies will build upon a wealth of knowledge gleaned from prior cross-sectional designs to identify early predictors of variability in cognitive function during aging, and characterize fundamental neurobiological mechanisms that underlie the vulnerability to, and the trajectory of, cognitive decline. Finally, we present examples of biological measures that may differentiate mechanisms of the cognitive reserve at the molecular, cellular, and network level.

Munden V. Bannock County

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Diet Of An Important Wetland Resident, The California Killifish, Fundulus Parvipinnis, In A Natural And Created Marsh Habitat In Mission Bay, California, Katie Robinson-Filipp

Theses

The California killifish, Fundulus parvipinnis Girard, is an ecologically important marsh resident. Fundulus parvipinnis is a low-level carnivore, displaying high-site fidelity and occurring in high densities across a range of environmental conditions. Despite the importance of F. parvipinnis to the ecosystem functions of the threatened coastal wetlands of southern California and the Baja California Peninsula, there are critical gaps in our knowledge of this species. In particular, information on their diet and food habits is lacking.

Understanding wetland food web linkages, interactions, and trophic transfer is essential for informing effective habitat management and contributes to our ability to evaluate the …

Therapeutic Development Of Group B Streptococcus Meningitis By Targeting A Host Cell Signaling Network Involving Egfr, Ningyu Zhu, Chengxian Zhang, Atish Prakash, Zheng Hou, Wei Liu, Weifeng She, Andrew J. Morris, Kwang Sik Kim

Gill Heart & Vascular Institute Faculty Publications

Group B Streptococcus (GBS) remains the most common Gram‐positive bacterium causing neonatal meningitis and GBS meningitis continues to be an important cause of mortality and morbidity. In this study, we showed that GBS penetration into the brain occurred initially in the meningeal and cortex capillaries, and exploits a defined host cell signaling network comprised of S1P₂, EGFR, and CysLT1. GBS exploitation of such network in penetration of the blood–brain barrier was demonstrated by targeting S1P₂, EGFR, and CysLT1 using pharmacological inhibition, gene knockout and knockdown cells, and gene knockout animals, as well as interrogation of the …

Lindenwood Sciences Prepare Students For Real Success, Lindenwood University

Archived Lindenwood Press Releases

No abstract provided.

2021-January-21-Tiny Mammal Teeth Reveal Ancient Climates, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY (January 21, 2021) – If you were planning a visit to Gray, Tennessee, five million years ago, you would want to dress like you were headed to Atlanta, Georgia, but pack rain gear like you would for Tampa, Florida. That’s according to an estimate of the ancient climate of the Gray Fossil Site, part of the results of a new study that uses fossil teeth to explore how climate has changed across North America over the past 37 million years.

It might not seem obvious at first, but teeth are related to climate. In any given place, the …

Dave Martinidez, Cardozo’S Beloved Dean Of Admissions, Passes Away, Benjamin N. Cardozo School Of Law

Cardozo News 2021

The Cardozo community is deeply saddened to announce that David Martinidez, the Associate Dean of Admissions, died of complications from cancer on January 19 th .

Munden V. Bannock County Appellant's Brief Dckt. 47978

Idaho Supreme Court Records & Briefs, All

No abstract provided.

The Effect Of Alcalase Concentration On The Proteins From The Shells Of Litopenaeus Setiferus (White Shrimp), Liam T. Quan

Journal of the South Carolina Academy of Science

Chitin is a naturally abundant polymer that also happens to be biodegradable. Chitin can be used in a variety of different products such as biodegradable plastics, papers, medical products, foods, and medical treatments. To extract chitin, shells must be demineralized and deproteinized. The goal of this experiment was to examine the effect of the protease Alcalase in the deproteinization of litopenaeus setiferus shells. The hypothesis was that if the concentration of Alcalase increased, then the absorbance of proteins in the spectrophotometer reading would increase. The null hypothesis was that if the concentration increased there would be no change in absorption. …

The Effect Of Whey, Azadirachta Indica, And Powdered Whole Milk On Monilinia Fructicola, Evelyn Plakal

Journal of the South Carolina Academy of Science

No abstract provided.

Wmu Board Of Trustees Formal Session January 21, 2021, Wmu Board Of Trustees

WMU Board of Trustees Meetings

• Acceptance of the Agenda – Chen-Zhang
• Approval of the Minutes (December 12, 2019 Meeting) – Chen-Zhang
• Remarks by the Chair – Chen-Zhang
• Remarks by the President – Montgomery
• Comments by the Faculty Senate President – Kritzman
• Comments by the Western Student Association President – West
• Comments by the Graduate Student Association President – Morris
• Presentation – Arcadia Flats – Anderson
• Presentation – Connecting with Students: Retention through Coordinated Outreach – Bott
• Public Comments Regarding Action Items – Schuemann

• Action Items – Chen-Zhang

• Board of Trustee Officer Election – Schuemann
  Consumers Energy Utility Easement Request– Van Der Kley
  Amendment to the …

Intergenerative Transdisciplinarity In “Glocal” Learning And Collaboration, Peter J. Whitehouse

Faculty Scholarship

In this report, authors from North America, Africa, Europe, and Asia share commonalities and differences in the lessons we are learning from COVID-19, especially about scholarship and collaboration. We represent different ages and disciplines hence our focus on intergenerational perspectives and transdisciplinary considerations. Our work is intergenerative{that is going "between to go beyond" by connecting creative sources of culture and focusing on the emergent, that is responding to changes in the context in which we work. And importantly in our view, we will point beyond whatever the next phase of COVID or even the next pandemic brings to a more …

“Communication Is Important. I Learned That On The Fresh Prince Show.” Soft Skills Portrayed In Five Prime-Time Television Comedies: A Quantitative Content Analysis, Jacquelyn Bader

Graduate Theses & Dissertations

This research study merged the seemingly divergent challenges of a soft skills shortage among workforce-ready young adults and the need to develop curricula that are interesting enough to hold students’ attention. This study, based on social learning and human capital theories, explored the portrayal of soft skills in five prime-time television (TV) comedies from the 2019-2020 broadcast season, with the idea that, if the portrayals were sufficiently frequent, readily identifiable, and led to what the TV characters wanted to achieve by exercising those skills, then perhaps the viewing of TV comedies could constitute part of the elusive yet engaging and …

Nanoparticle T-Cell Engagers As A Modular Platform For Cancer Immunotherapy, Kinan Alhallak, Jennifer Sun, Katherine Wasden, Nicole Guenthner, Julie O'Neal, Barbara Muz, Justin King, Daniel Kohnen, Ravi Vij, Samuel Achilefu, John F Dipersio, Abdel Kareem Azab

Open Access Publications

T-cell-based immunotherapy, such as CAR-T cells and bispecific T-cell engagers (BiTEs), has shown promising clinical outcomes in many cancers; however, these therapies have significant limitations, such as poor pharmacokinetics and the ability to target only one antigen on the cancer cells. In multiclonal diseases, these therapies confer the development of antigen-less clones, causing tumor escape and relapse. In this study, we developed nanoparticle-based bispecific T-cell engagers (nanoBiTEs), which are liposomes decorated with anti-CD3 monoclonal antibodies (mAbs) targeting T cells, and mAbs targeting the cancer antigen. We also developed a nanoparticle that targets multiple cancer antigens by conjugating multiple mAbs against …

Library Environment :Microbial Quality Assessment And Antibacterial Activity Of Cinnamomum Verum And Piper Nigrum With Respect To Microorganisms Of Srcw Library, Shyamala R, Mekala M

Library Philosophy and Practice (e-journal)

Abstract

BACKGROUND:

Background research interest focuses on medicinal herbs such as Cinnamomum verum and Piper nigrum extracts can be used to trap the microbes from the atmosphere.

• To collect bark of Cinnamomum verum and Piper nigrum plants and make a dry powder.
• To perform Phytochemicals analysis for the extracted powder.
• To perform antimicrobial susceptibility test and MIC against different strains.
• To develop herbal coated tissue paper.

METHODOLOGY:

• The bark of Cinnamomum verum and Piper nigrum were collected and finely powdered.
• Different extracts of C. verum and P. nigrum (10 μl to 40 μl) were loaded on to the wells of …

Fictional Characters And Their Discontents : A Prolegomena To Any Future Metaphysics Of Fictional Entities, Shamik Chakravarty

Lingnan Theses (MPhil & PhD)

In recent metaphysics, the questions of whether fictional entities exist, what their nature is, and how to explain truths of statements such as “Sherlock Holmes lives in 221B Baker Street” and “Holmes was created by Arthur Conan Doyle” have been subject to much debate. The main aim of my thesis is to wrestle with key proponents of the abstractionist view that fictional entities are abstract objects that exist (van Inwagen 1977, 2018, Thomasson 1999 and Salmon 1998) as well as Walton’s (1990) pretense view, which denies the existence of such entities. In the process, I propose modifications to these views …

Associations Of Maternal Dietary Inflammatory Potential And Quality With Offspring Birth Outcomes: An Individual Participant Data Pooled Analysis Of 7 European Cohorts In The Alphabet Consortium, Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Elzbieta Trafalska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Liesbeth Duijts, Barbara Heude, James R. Hébert Scd, Fionnuala M. Mcauliffe, Cecily C. Kelleher, Catherine M. Phillips

Faculty Publications

Background

Adverse birth outcomes are major causes of morbidity and mortality during childhood and associate with a higher risk of noncommunicable diseases in adult life. Maternal periconception and antenatal nutrition, mostly focusing on single nutrients or foods, has been shown to influence infant birth outcomes. However, evidence on whole diet that considers complex nutrient and food interaction is rare and conflicting. We aim to elucidate the influence of whole-diet maternal dietary inflammatory potential and quality during periconceptional and antenatal periods on birth outcomes.

Methods and findings

We harmonized and pooled individual participant data (IPD) from up to 24,861 mother–child pairs …

Increased Carbon Capture By A Silicate-Treated Forested Watershed Affected By Acid Deposition, Lyla L. Taylor, Charles T. Driscoll, Peter M. Groffman, Greg H. Rau, Joel D. Blum, David J. Beerling J. Beerling

Advanced Science Research Center

Meeting internationally agreed-upon climate targets requires carbon dioxide removal (CDR) strategies coupled with an urgent phase-down of fossil fuel emissions. However, the efficacy and wider impacts of CDR are poorly understood. Enhanced rock weathering (ERW) is a land-based CDR strategy requiring large-scale field trials. Here we show that a low 3.44 t ha−1 wollastonite treatment in an 11.8 ha acid-rain-impacted forested watershed in New Hampshire, USA, led to cumulative carbon capture by carbonic acid weathering of 0.025–0.13 t CO2 ha−1 over 15 years. Despite a 0.8–2.4 t CO2 ha−1 logistical carbon penalty from mining, grinding, transportation, and spreading, by 2015 …

What Can A Worm Learn? Nonlinear Categorization By Caenorhabditis Elegans Using A Hydrochloric Acid Gradient, Parth Desai

Journal of the South Carolina Academy of Science

No abstract provided.

Spliceosome-Targeted Therapies Trigger An Antiviral Immune Response In Triple-Negative Breast Cancer, William Wu, Nicholas J Neill, Ik Sun Kim, Siddhartha Tyagi, Mayra Orellana, Sarah J Kurley, Rocio Dominguez-Vidaña, Hsiang-Ching Chung, Tiffany Y-T Hsu, Julien Dubrulle, Alexander B Saltzman, Heyuan Li, Jitendra K Meena, Gino M Canlas, Srinivas Chamakuri, Swarnima Singh, Lukas M Simon, Calla M Olson, Lacey E Dobrolecki, Michael T Lewis, Bing Zhang, Ido Golding, Jeffrey M Rosen, Damian W Young, Anna Malovannaya, Fabio Stossi, George Miles, Matthew J Ellis, Lihua Yu, Silvia Buonamici, Charles Y Lin, Kristen L Karlin, Xiang H-F Zhang, Thomas F Westbrook

Faculty, Staff and Students Publications

Many oncogenic insults deregulate RNA splicing, often leading to hypersensitivity of tumors to spliceosome-targeted therapies (STTs). However, the mechanisms by which STTs selectively kill cancers remain largely unknown. Herein, we discover that mis-spliced RNA itself is a molecular trigger for tumor killing through viral mimicry. In MYC-driven triple-negative breast cancer, STTs cause widespread cytoplasmic accumulation of mis-spliced mRNAs, many of which form double-stranded structures. Double-stranded RNA (dsRNA)-binding proteins recognize these endogenous dsRNAs, triggering antiviral signaling and extrinsic apoptosis. In immune-competent models of breast cancer, STTs cause tumor cell-intrinsic antiviral signaling, downstream adaptive immune signaling, and tumor cell death. Furthermore, RNA …

Mussel Musings On The Powell River, Aggy Vanderpool

Cumberland Mountain Naturalist

No abstract provided.

"Of Cabbages And Kings": Biographies For Children, Leah Van Belle

Michigan Reading Journal

No abstract provided.

Assessing Reading Knowledge With An Informal Reading Inventory And Connecting The Results With Informal Instructional Assessment, Tanya Christ, Ron Cramer

Michigan Reading Journal

No abstract provided.

The Directed Reading-Thinking Activity: Developing Thoughtful Predictions & Thoughtful Readers, Lisa Wujczyk

Michigan Reading Journal

No abstract provided.

Couched Literacy: Family Interactions With Texts At Home, Paula S. Vergunst, Susan V. Piazza

Michigan Reading Journal

No abstract provided.

The Well-Stocked Bookshelf: Must Reads, Ed Spicer

Michigan Reading Journal

No abstract provided.

Book Awards: A Key To Gems From New And Established Authors And Illustrators, Karen I. Adams, Leah Van Belle

Michigan Reading Journal

No abstract provided.