Digital Commons Network^™

Satellite-Based Modelling Of Potential Tsetse (Glossina Pallidipes) Breeding And Foraging Sites Using Teneral And Non-Teneral Fly Occurrence Data, Stella Gachoki, Thomas Groen, Anton Vrieling, Michael Okal, Andrew Skidmore, Daniel Masiga

All Peer-Reviewed Publications

Background: African trypanosomiasis, which is mainly transmitted by tsetse flies (Glossina spp.), is a threat to public health and a significant hindrance to animal production. Tools that can reduce tsetse densities and interrupt disease transmission exist, but their large-scale deployment is limited by high implementation costs. This is in part limited by the absence of knowledge of breeding sites and dispersal data, and tools that can predict these in the absence of ground-truthing. Methods: In Kenya, tsetse collections were carried out in 261 randomized points within Shimba Hills National Reserve (SHNR) and villages up to 5 km from the reserve …

Water Immersion Tolerance By Larval Instars Of Stable Fly, Stomoxys Calcitrans, L1758 (Diptera: Muscidae) Impairs The Fitness Performance Of Their Subsequent Stages, Steve B.S. Baleba

All Peer-Reviewed Publications

Background: In holometabolous insects, environmental factors experienced in pre-imaginal life stages affect the life-history traits within that stage and can also influence subsequent life stages. Here, I assessed tolerance to water immersion by the larval instars of the stable fly, Stomoxys calcitrans L. (Diptera: Muscidae) and its impact on the life-history traits of their subsequent life stages. Results: After submerging the three larval instars of S. calcitrans in distilled water, I found that the first instar larvae remained active for longer as compared to the second and third instar larvae. Also, the first instar larvae took a longer period to …

Ehrlichia Spp. Close To Ehrlichia Ruminantium, Ehrlichia Canis, And “Candidatus Ehrlichia Regneryi” Linked To Heartwater-Like Disease In Kenyan Camels (Camelus Dromedarius), Mario Younan, Daniel O. Ouso, Boku Bodha, Edward K. Keitany, Hezron O. Wesonga, Rinah Sitawa, Joshua Kimutai, Wilson Kuria, Wario Sori Sake, Nicholas Svitek, Tobias Landmann, Diba Dida Wako, Jandouwe Villinger

All Peer-Reviewed Publications

We present findings from an outbreak of a heartwater-like disease in camels that killed at least 2000 adult animals in Kenya in 2016. Clinical signs included excitability, head pressing, aimless wandering, recumbency, and fast breathing followed by death after about 4 days. The observed morbidity in one herd was 40% with an average mortality of 7.5% in animals that received early antibiotic treatments. In untreated adults, the case fatality rate reached 100%. Gross pathology showed pulmonary edema, pleural exudate, hydrothorax, hydropericardium, ascites, enlarged “cooked” liver, nephrosis, and blood in the abomasum and intestine. Using established PCR-based protocols for tick-borne pathogens, …

Gene Co-Expression Network Analysis Of Trypanosoma Brucei In Tsetse Fly Vector, Kennedy W. Mwangi, Rosaline W. Macharia, Joel L. Bargul

All Peer-Reviewed Publications

Background: Trypanosoma brucei species are motile protozoan parasites that are cyclically transmitted by tsetse fly (genus Glossina) causing human sleeping sickness and nagana in livestock in sub-Saharan Africa. African trypanosomes display digenetic life cycle stages in the tsetse fly vector and in their mammalian host. Experimental work on insect-stage trypanosomes is challenging because of the difficulty in setting up successful in vitro cultures. Therefore, there is limited knowledge on the trypanosome biology during its development in the tsetse fly. Consequently, this limits the development of new strategies for blocking parasite transmission in the tsetse fly. Methods: In this study, RNA-Seq …

Plant Nutrient Quality Impacts Survival And Reproductive Fitness Of The Dengue Vector Aedes Aegypti, Vincent Odhiambo Nyasembe, David Poumo Tchouassi, Martha Njeri Muturi, Christian W.W. Pirk, Catherine L. Sole, Baldwyn Torto

All Peer-Reviewed Publications

Background: In a recent study using DNA barcoding, we identified the plants fed upon by four Afro-tropical mosquito species that vector dengue, malaria, and Rift Valley fever. Herein, we have expanded on this study by investigating the role of three of the plants, Pithecellobium dulce (Fabaceae), Leonotis nepetifolia (Lamiaceae), and Opuntia ficus-indica (Cactaceae), on the survival, fecundity, and egg viability of the dengue vector Aedes aegypti. Methods: We tested these effects using females that received (i) an initial three rations of blood meals and (ii) no blood meal at all. Two controls were included: age-matched females fed on glucose solution …

Molecular Prevalence And Risk Factors Associated With Tick-Borne Pathogens In Cattle In Western Kenya, Tatenda Chiuya, Jandouwe Villinger, Daniel K. Masiga, Dickens O. Ondifu, Maurice K. Murungi, Lillian Wambua, Armanda D.S. Bastos, Eric M. Fèvre, Laura C. Falzon

All Peer-Reviewed Publications

Background: Tick-borne pathogens (TBPs) are of global importance, especially in sub-Saharan Africa where they represent a major constraint to livestock production. Their association with human disease is also increasingly recognized, signalling their zoonotic importance. It is therefore crucial to investigate TBPs prevalence in livestock populations and the factors associated with their presence. We set out to identify TBPs present in cattle and to determine associated risk factors in western Kenya, where smallholder livestock production is important for subsistence and market-driven income. Results: Tick-borne pathogen infections in blood samples collected from cattle at livestock markets and slaughterhouses between May 2017 and …

Noise Types Adaptation For Speech Enhancement With Recurrent Neural Network, Xiang Lan

All Theses

Speech enhancement is a critical part in automatic speech recognition systems. Recently with the development of deep learning based techniques, those speech enhancement systems trained with neural networks can significantly improve performance. While many of the latest speech enhancement systems show advantages in maximizing the perceptual quality of the noisy signals, they expose drawbacks when the test noisy signals have noise types that never exist during the system training process. The systems have relatively poor performance when handling noisy signals with unseen noise in contrast to noisy signals with seen noise. The dissimilarity between the training and testing circumstances can …

In The Pines: Dung Beetle Community Composition In Longleaf Pine Habitat, Kelsea Lynn Young

All Theses

Dung beetle assemblages are recognized as ecological bioindicators, allowing us to monitor ecological impacts by observing community shifts. Acting as primary nutrient cyclers, they establish niche segregation by sometimes selecting dung based on species (e.g. coyote vs. deer) and by using dung in different ways (e.g. rollers vs. tunnelers). Longleaf pine savannahs are recognized as global hotspots for diversity. Species of dung beetles found within these ecosystems may differ substantially from those found in surrounding agricultural, residential or other forest land. Our objective was to investigate whether the exclusion of mammalian meso-predator exclusion impacts dung beetle abundance, species composition and …

Effect Of Metal Ions On Stability Of Ascorbic Acid And Niacin Determined By Hplc, Jhongyan Huang

All Theses

Water-soluble vitamins, such as vitamin C and vitamin B, exist in various food stuffs, including vegetables, fruits, fortified grains, milk, and meat, etc. Those vitamers play essential roles in many biochemical functions in human body, thus are significant components for maintaining human health. However, the stability of vitamers is susceptible to many factors, such as light, temperature, metal ions, levels of oxygen concentration, and moisture contents, etc. As vitamers are prone to further degradation, their bioactivities can be remarkably affected and even lost in food processing and food products.In this study, effect of different metal ions (i.e., Na+, K+, Ca2+, …

An Analysis Of Environmental Conditions Impacting Cyanobacterial Algal Blooms In Drinking Water Sources In Upstate South Carolina, Gregory Langlois

All Theses

Maintaining water quality in reservoirs used for drinking water has been an issue in recent years due to the presence of algal blooms. Algal blooms are a perennially recurring problem that can have negative impacts on tourism, recreation, and overall water quality. Additionally, algal blooms will often produce an assortment of chemicals, some of which are hazardous to the health of humans, and some of which that, while relatively innocuous, result in unpleasant tastes and odors in water. Geosmin and 2-methylisoborneol are two taste and odor compounds that are notoriously difficult to treat out of drinking water sources by traditional …

Damned Ol' Dirt, Molly Morningglory

All Theses

damned ol’ dirt centers mindfulness and embodiment practices to foster relationships with the self, each other, and the land. These relationships intend to collectively imagine and then build an emotionally and environmentally sustainable and joyful future. My practice foregrounds clay with digital video, photography, and fabric dyeing, recording the imprint of performance. I use my hereditary understanding of clay and fibers, a trained attunement to the natural world, and my background of performance in craft (via demonstration of tactile techniques) to transfer knowledge and skill to the viewer. Through the creation of tableaus and documents of rituals based in materiality, …

Effects Of Cashew Nut Shell Extract On Nutrient Digestibility And Ruminal Fermentation Under In Vitro Batch Culture And Continuous Culture Conditions, Chandler Compton

All Theses

The overall objective of this research was to determine the effects of cashew nut shell extract (CNSE; 59% anacardic acid and 18% cardol) on nutrient digestibility and rumen fermentation profile under in vitro batch culture (Chapter 2) and continuous culture conditions (Chapter 3). The second objective was to determine an optimal supplementation dosage for dairy cows. The batch culture study was organized as a randomized complete block design with 15 replicates per treatment incubated for 24 h during four incubation runs. Each incubation was inoculated with rumen contents collected from ruminally fistulated cows fed either a close-up ( …

How “Interested” Criticism Fueled The Formulation Of Nineteen Eighty-Four’S Cultural Afterlife, John Cameron Bosch

All Theses

George Orwell’s Nineteen Eighty-Four carries a “cultural afterlife” as a result of “interested” criticism, which has a set political/practical barometer or motive. While everyone agrees that the novel presents a frightening dystopia, many also consider it a prophetic piece that illuminates the possible corruption of executive power of a nation thanks to this cultural afterlife; the modern and popular term “Orwellian” resulted from these sorts of analyses and have only escalated in the years since its inception. As a result, within the past decade, multiple scholars, analysts, and journalists have referenced Orwell’s novel as a factual representation of this executive …

Chasing Target Zero: Contributing Factors Of Fatal Crashes In South Carolina, Matthew Stanley

All Theses

South Carolina consistently ranks in the top-10 in fatal crashes per 100,000 capita and 100 million vehicle miles traveled. This thesis summarizes an analysis of contributing factors for fatal crashes in South Carolina. A primary objective of this thesis is to investigate differences in contributing factors for fatal crashes as compared to all crashes in South Carolina. 2018 South Carolina fatal crashes (N=970) and all crashes (N=152,973) were analyzed and compared using classic Venn diagrams to compare differences in contributing factors between fatal crashes and all crashes. Fatal, non-fatal, and all crashes were aggregated into one of seven possible contributing …

Studies In Consumption And Production Of South Carolina Aquaculture Products, David Cheplick

All Theses

Market demand for seafood products among South Carolina (SC) consumers has led to increased aquaculture production as a means of supporting the seafood supply chain across the state. Our objective is broken into four distinct parts; (1) understanding consumer’s preferences and perceptions of seafood, (2) calculating their willingness to pay (WTP) for seafood products available in SC using attributes of sustainability and locality; and (3) gathering production metric and anecdotal data from SC oyster growers. Previous research assessing the market channels of seafood in South Carolina is compared to survey results. Respondents indicated that taste and quality were the most …

Investigation On Effects Of Lactate Adaptation Using Metabolic Indicators And Amino Acids To Explore Cell Metabolism, Lisa Uy

All Theses

Biopharmaceutical products are drugs that are made from living cells. One protein type of high importance to biopharmaceuticals is monoclonal antibodies. Monoclonal antibodies allow for highly specific, targeted treatment of diseases and detection of molecules related to diseases. With major roles in detecting and/or treating diseases like human immunodeficiency virus (HIV), coronavirus disease 2019 (COVID-19), and some cancers, monoclonal antibodies are in demand. This demand has led to a need for efficient cell culture systems to produce high yields of protein with minimal waste. The most commonly used cell culture system for these high-value proteins is Chinese hamster ovary (CHO) …

The Use Doctrine In Trademark Law: Issues From Trade And Transborder Reputation, Srividhya Ragavan

Faculty Scholarship

Mindful of the current trend within the United States to revive the focus on the use of trademark to determine a mark’s ability to act as a source indicator, in this paper I highlight how focusing on use can create disparate results by examining the role of use when dealing with well-known marks. Hence, this paper implicates the prescriptions from the harmonized trade regime, especially trademark law. In doing so, the paper outlines larger public policy concerns that will ensue especially considering the role of the use doctrine in the context of international harmonization of protection of well-known trademarks. In …

Integrity, Freedom, And Trust – A Comprehensive Understanding Of Corruption And Its Effect On Human Rights, Nelu Burcea, Lucile Sabas, Carlos Biaggi

Faculty Publications

Book of Abstracts, UNEQUAL WORLD Conference Third Edition

Efficacy Of Sediment Contaminant Remediation Of The Benthos In A Segment Of The Southern Branch Of The Elizabeth River, Colton Martin

Biological Sciences Theses & Dissertations

The bottom sediment of the Southern Branch of the Elizabeth River, a tributary of Chesapeake Bay, was historically contaminated with hydrocarbons from industrial sources especially wood treatment facilities. The Elizabeth River Project selected a section of the bottom off Money Point in the Southern Branch for a sediment contaminant remediation effort. Prior to initiation of remediation efforts, a survey occurred in summer 2010 to characterize the ecological condition of the benthic communities off Money Point compared to benthic communities of a benthic region across the channel and northwest of Money Point near Blows Creek. That study characterized the benthos of …

Population Connectivity In Voles (Microtus Sp.) As A Gauge For Tall Grass Prairie Restoration In Midwestern North America, Marlis R. Douglas, Steven M. Mussmann, Tyler Chafin, Whitney J.B. Anthonysamy, Mark A. Davis, Matthew P. Mulligan, Robert L. Schooley, Wade Louis, Michael E. Douglas

Biological Sciences Faculty Publications and Presentations

Ecological restoration can promote biodiversity conservation in anthropogenically fragmented habitats, but effectiveness of these management efforts need to be statistically validated to determine ’success.’ One such approach is to gauge the extent of recolonization as a measure of landscape permeability and, in turn, population connectivity. In this context, we estimated dispersal and population connectivity in prairie vole (Microtus ochrogaster; N = 231) and meadow vole (M. pennsylvanicus; N = 83) within five tall-grass prairie restoration sites embedded within the agricultural matrix of midwestern North America. We predicted that vole dispersal would be constrained by the …

Cnidarian Hair Cell Development Illuminates An Ancient Role For The Class Iv Pou Transcription Factor In Defining Mechanoreceptor Identity, Ethan Ozment, Arianna N. Tamvacakis, Jianhong Zhou, Pablo Yamild Rosiles-Loeza, Estaban Elias Escobar-Hernandez, Selene L. Fernandez-Valverde, Nagayasu Nakanishi

Biological Sciences Faculty Publications and Presentations

Although specialized mechanosensory cells are found across animal phylogeny, early evolutionary histories of mechanoreceptor development remain enigmatic. Cnidaria (e.g. sea anemones and jellyfishes) is the sister group to well-studied Bilateria (e.g. flies and vertebrates), and has two mechanosensory cell types - a lineage-specific sensory effector known as the cnidocyte, and a classical mechanosensory neuron referred to as the hair cell. While developmental genetics of cnidocytes is increasingly understood, genes essential for cnidarian hair cell development are unknown. Here, we show that the class IV POU homeodomain transcription factor (POU-IV) - an indispensable regulator of mechanosensory cell differentiation in Bilateria and …

Comparative Metabolism Of Aflatoxin B1 In Two Quail Genera Coturnix Japonica And Callipepla Californica, Sean Moody

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Avian species are highly susceptible to the hepatotoxic mycotoxin aflatoxin B₁ (AFB₁). Domesticated turkeys are exquisitely sensitive, due to a combination of highly-efficient hepatic cytochrome P450 (CYP)-mediated bioactivation, and to dysfunctional alpha-class glutathione S-transferases (GSTAs) which typically detoxify the bioactivated electrophilic metabolite exo-AFB₁-8,9-epoxide (AFBO). Wild turkeys are relatively resistant to AFB₁ in large part due to expression of functional GSTAs. Quail, a related Galliforme, are slightly less sensitive in vivo to AFB₁, but whether this is related to the hepatic metabolic profiles of these two critical enzymes has not been rigorously evaluated. …

Absorption Kinetics Of Berberine And Dihydroberberine And Their Impact On Glycemia: A Randomized, Controlled, Crossover Pilot Trial, Jessica M. Moon, Kayla M. Ratliff, Anthony M. Hagele, Richard A. Stecker, Petey W. Mumford, Chad M. Kerksick

Faculty Scholarship

Berberine is a natural alkaloid used to improve glycemia but displays poor bioavailability and increased rates of gastrointestinal distress at higher doses. Recently, dihydroberberine has been developed to combat these challenges. This study was designed to determine the rate and extent to which berberine appeared in human plasma after oral ingestion of a 500 mg dose of berberine (B500) or 100 mg and 200 mg doses of dihydroberberine (D100 and D200). In a randomized, double-blind, crossover fashion, five males (26 ± 2.6 years; 184.2 ± 11.6 cm; 91.8 ± 10.1 kg; 17.1 ± 3.5% fat) completed a four-dose supplementation protocol …

The Use Doctrine In Trademark Law: Issues From Trade And Transborder Reputation, Srividhya Ragavan

Cardozo Law Review

No abstract provided.

Triple Oxygen Isotope Constraints On Atmospheric O2 And Biological Productivity During The Mid-Proterozoic, Peng Liu, Jingjin Liu, Aoshaung Ji, Christopher T. Reinhard, Noah J. Planavsky, Dmitri Babikov, Raymond G. Najjar, James F. Kasting

Chemistry Faculty Research and Publications

Reconstructing the history of biological productivity and atmospheric oxygen partial pressure (pO₂) is a fundamental goal of geobiology. Recently, the mass-independent fractionation of oxygen isotopes (O-MIF) has been used as a tool for estimating pO₂ and productivity during the Proterozoic. O-MIF, reported as Δ′¹⁷O, is produced during the formation of ozone and destroyed by isotopic exchange with water by biological and chemical processes. Atmospheric O-MIF can be preserved in the geologic record when pyrite (FeS₂) is oxidized during weathering, and the sulfur is redeposited as sulfate. Here, sedimentary sulfates from …

The Lumberjack, December 01-B, 2021

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

Moral Injury In Sexual Brokenness: Using Military Models Of Mi To Address Civilian Issues, Vanessa M. Close

Theology Undergraduate Work

Moral injury (MI) has long been an emotional and psychological wound carried by military servicemembers in response to their experiences during war or active duty. Since the conception of moral injury in the late 20th century, dedication toward researching the topic has increased to provide better psychological treatment to veterans and active-duty military. As a result of an increased understanding of MI, researchers have begun to explore the application of MI models to civilian experiences and traumas. This paper seeks to join the conversation through exploring the occurrence of moral injury throughout a unique state of sexual distress labeled by …

Handbook For Sdg-Aligned Food Companies: Four Pillar Framework Standards, Nora Mardirossian, GaëLle Espinosa, Rico RincóN, Diana Marcela, Erin O’Dwyer, Abrania Marrero, Regan Plekenpol, Claudia P. Baethgen, Urvi Agarwal, Lisa E. Sachs, Jeffrey D. Sachs

Columbia Center on Sustainable Investment Staff Publications

The world food system is in crisis. Outright hunger, unhealthy diets and malnutrition occur parallel to food losses and waste. Farming families in poor countries suffer from extreme poverty. And food production is environmentally unsustainable and increasingly vulnerable to extreme weather events caused by climate change. A historic change of direction is needed to bring about a new era of food system sustainability. Our work aims to help companies, investors and other stakeholders move towards a more sustainable food system that is aligned with the Sustainable Development Goals.

Transforming the world food system to achieve sustainability in all its dimensions …

Newsletter Catholic Deaf Of Detroit, December 2021

Newsletter Catholic Deaf of Detroit

A newsletter published for Deaf Catholics in Detroit, MI

Newsletter Catholic Deaf of Detroit Finding Aid

Expanding The Conservation Genomics Toolbox: Incorporating Structural Variants To Enhance Genomic Studies For Species Of Conservation Concern, Stephanie J. Galla

Biology Faculty Publications and Presentations

Structural variants (SVs) are large rearrangements (>50 bp) within the genome that impact gene function and the content and structure of chromosomes. As a result, SVs are a significant source of functional genomic variation, that is, variation at genomic regions underpinning phenotype differences, that can have large effects on individual and population fitness. While there are increasing opportunities to investigate functional genomic variation in threatened species via single nucleotide polymorphism (SNP) data sets, SVs remain understudied despite their potential influence on fitness traits of conservation interest. In this future-focused Opinion, we contend that characterizing SVs offers the conservation genomics …