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2020

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Articles 166951 - 166980 of 169265

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3d Magneto-Buoyancy-Thermocapillary Convection Of Cnt-Water Nanofluid In The Presence Of A Magnetic Field, Lioua Kolsi, Salem Algarni, Hussain A. Mohammed, Walid Hassen, Emtinene Lajnef, Walid Aich, Mohammed Almeshaal Jan 2020

3d Magneto-Buoyancy-Thermocapillary Convection Of Cnt-Water Nanofluid In The Presence Of A Magnetic Field, Lioua Kolsi, Salem Algarni, Hussain A. Mohammed, Walid Hassen, Emtinene Lajnef, Walid Aich, Mohammed Almeshaal

Research outputs 2014 to 2021

Anumerical study is performed to investigate the effects of adding Carbon Nano Tube (CNT) and applying a magnetic field in two directions (vertical and horizontal) on the 3D-thermo-capillary natural convection. The cavity is differentially heated with a free upper surface. Governing equations are solved using the finite volume method. Results are presented in term of flow structure, temperature field and rate of heat transfer. In fact, results revealed that the flow structure and heat transfer rate are considerably affected by the magnitude and the direction of the magnetic field, the presence of thermocapillary forces and by increasing nanoparticles volume fraction. …

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A Sensorimotor Control Framework For Understanding Emotional Communication And Regulation, Justin H.G. Williams, Charlotte F. Huggins, Barbra Zupan, Megan Willis, Tamsyn E. Van Rheenen, Wataru Sato, Romina Palermo, Catherine Ortner, Martin Krippl, Mariska Kret, Joanne M. Dickson, Chiang-Shan R. Li, Leroy Lowe Jan 2020

A Sensorimotor Control Framework For Understanding Emotional Communication And Regulation, Justin H.G. Williams, Charlotte F. Huggins, Barbra Zupan, Megan Willis, Tamsyn E. Van Rheenen, Wataru Sato, Romina Palermo, Catherine Ortner, Martin Krippl, Mariska Kret, Joanne M. Dickson, Chiang-Shan R. Li, Leroy Lowe

Research outputs 2014 to 2021

Our research team was asked to consider the relationship of the neuroscience of sensorimotor control to the language of emotions and feelings. Actions are the principal means for the communication of emotions and feelings in both humans and other animals, and the allostatic mechanisms controlling action also apply to the regulation of emotional states by the self and others. We consider how motor control of hierarchically organised, feedback-based, goal-directed action has evolved in humans, within a context of consciousness, appraisal and cultural learning, to serve emotions and feelings. In our linguistic analysis, we found that many emotion and feelings words …

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Medical-Attention Injuries In Community Cricket: A Systematic Review, Geordie Mcleod, Siobhan O'Connor, Damian Morgan, Alex Kountouris, Caroline F. Finch, Lauren V. Fortington Jan 2020

Medical-Attention Injuries In Community Cricket: A Systematic Review, Geordie Mcleod, Siobhan O'Connor, Damian Morgan, Alex Kountouris, Caroline F. Finch, Lauren V. Fortington

Research outputs 2014 to 2021

Objectives: The aim was to identify and describe outcomes from original published studies that present the number, nature, mechanism and severity of medically treated injuries sustained in community-level cricket. Design: Systematic review. Methods: Nine databases were systematically searched to December 2019 using terms "cricket∗" and "injur∗". Original, peer-reviewed studies reporting injury for at least one injury descriptor (body region, nature of injury and/or mechanism of injury) in community-level cricketers of all ages were included. Qualitative synthesis, critical appraisal and descriptive summary results are reported within the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Results: Six studies were …

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Correction To: Bilingualism Is Associated With A Delayed Onset Of Dementia But Not With A Lower Risk Of Developing It: A Systematic Review With Meta-Analyses, Stefano Brini, Hamid R. Sohrabi, Jeffrey J. Hebert, Mitchell R. L. Forrest, Matti Laine, Heikki Hämäläinen, Mira Karrasch, Jeremiah J. Peiffer, Ralph N. Martins, Timothy J. Fairchild Jan 2020

Correction To: Bilingualism Is Associated With A Delayed Onset Of Dementia But Not With A Lower Risk Of Developing It: A Systematic Review With Meta-Analyses, Stefano Brini, Hamid R. Sohrabi, Jeffrey J. Hebert, Mitchell R. L. Forrest, Matti Laine, Heikki Hämäläinen, Mira Karrasch, Jeremiah J. Peiffer, Ralph N. Martins, Timothy J. Fairchild

Research outputs 2014 to 2021

The original version of this article unfortunately contained the following mistakes. 1. In the Results section under the paragraph Disease Severity, the sentence “The PIs ranged between -0.47 and 0.57 MMSE points” should read -0.49 and 0.59 MMSE points. 2. In Figs. 3, 5, and 7, the labels “favour bilinguals” and “favours monolinguals” should be inverted. Therefore, it should be “favours monolinguals” and “favours bilinguals”. Please see below for the correct figures. © 2020, The Author(s).

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Solids Velocity Measurement Using Electric Capacitance Sensor Assemblies, Usama Abrar, Liu Shi, Nasif Raza Jaffri, Qin Li, Hassan Raza Sindhu, Mian Waqas Omar Jan 2020

Solids Velocity Measurement Using Electric Capacitance Sensor Assemblies, Usama Abrar, Liu Shi, Nasif Raza Jaffri, Qin Li, Hassan Raza Sindhu, Mian Waqas Omar

Research outputs 2014 to 2021

This paper covers the application of the cross-correlation method for measuring the velocity of solid particles. Capacitive electrodes are used as primary sensors to measure the time required by the solid particles to cover a known distance between the electrodes. The capacitive variations of both the electrode sensors are stored in computer synchronously for offline estimation of the velocity of the solid particles. Single glass marble is used as a solid particle to conduct the performance in the lab for its good signal to noise ratio (SNR) and vivid graphs. Matlab R2018a is used as a programming tool to perform …

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How Special Is Special Interest Tourism – And How Special Are Special Interest Tourists? A Perspective Article In A Chinese Context, Jun Wen, Mao-Ying Wu Jan 2020

How Special Is Special Interest Tourism – And How Special Are Special Interest Tourists? A Perspective Article In A Chinese Context, Jun Wen, Mao-Ying Wu

Research outputs 2014 to 2021

Special interest tourism has emerged as a valuable niche market for tourism destinations in the past decade. However, tourism scholars have generally struggled to answer McKercher and Chan’s [2005. How special is special interest tourism? Journal of Travel Research, 44(1), 21–31] question, ‘How special is special interest tourism?’ Such ambiguity extends to the related enquiry, ‘How special are special interest tourists?’, in attempting to define special interest tourists. This perspective research letter discusses these questions in terms of Chinese outbound tourism. Based upon the reflection of previous research, the authors’ thoughts and ongoing research in this area, knowledge …

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Rebuilding As Research: Noongar Song, Language And Ways Of Knowing, Clint Bracknell Jan 2020

Rebuilding As Research: Noongar Song, Language And Ways Of Knowing, Clint Bracknell

Research outputs 2014 to 2021

In Australia, language and song are integral to maintaining Aboriginal knowledge systems. British colonisation and ensuing Australian government policies of assimilation have adversely impacted these knowledge systems, at least partially by functioning to dramatically diminish the vitality of many Aboriginal languages and song traditions. As a Noongar researcher motivated by community-oriented goals, I employ a multidisciplinary approach to enhance the revitalisation of the endangered Noongar language and its song traditions in the south coast region of Western Australia. This work draws on established methods from ethnomusicology and linguistics, engaging with community knowledge-holders and archival records to rebuild repertoire while increasing …

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The Implications Of The Non-Linguistic Modes Of Meaning For Language Learners In Science: A Review, Melanie Williams Jan 2020

The Implications Of The Non-Linguistic Modes Of Meaning For Language Learners In Science: A Review, Melanie Williams

Research outputs 2014 to 2021

In response to the globally escalating number of language learners tasked with learning science through a foreign language, this review seeks to bring new perspectives by reframing research findings, still dominated by historical language assumptions, through a contemporary language lens. We aim to unearth, amalgamate and expose the potentials of non-linguistic modes described by the theory of multiliteracies that appear sporadic and fragmentary within studies due to their linguistic focus, as we surmise they offer language learners alternative avenues for meaning-making. 40 peer-reviewed empirical studies published between 1995 and 2019 were systematically found and examined using theoretical thematic analysis to …

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Vortex Fluidic Mediated Synthesis Of Polysulfone, Aghil Igder, Scott Pye, Ahmed Hussein Mohammed Al-Antaki, Alireza Keshavarz, Colin L. Raston, Ata Nosrati Jan 2020

Vortex Fluidic Mediated Synthesis Of Polysulfone, Aghil Igder, Scott Pye, Ahmed Hussein Mohammed Al-Antaki, Alireza Keshavarz, Colin L. Raston, Ata Nosrati

Research outputs 2014 to 2021

Polysulfone (PSF) was prepared under high shear in a vortex fluidic device (VFD) operating in confined mode, and its properties compared with that prepared using batch processing. This involved reacting the pre-prepared disodium salt of bisphenol A (BPA) with a 4,4′-dihalodiphenylsulfone under anhydrous conditions. Scanning electron microscopy (SEM) established that in the thin film microfluidic platform, the PSF particles are sheet-like, for short reaction times, and fibrous for long reaction times, in contrast to spherical like particles for the polymer prepared using the conventional batch synthesis. The operating parameters of the VFD (rotational speed of the glass tube, its tilt …

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Green And Secure Computation Offloading For Cache-Enabled Iot Networks, M. Ishtiaque A. Zahed, Iftekhar Ahmad, Daryoush Habibi, Quoc Viet Phung Jan 2020

Green And Secure Computation Offloading For Cache-Enabled Iot Networks, M. Ishtiaque A. Zahed, Iftekhar Ahmad, Daryoush Habibi, Quoc Viet Phung

Research outputs 2014 to 2021

The ever-increasing number of diverse and computation-intensive Internet of things (IoT) applications is bringing phenomenal growth in global Internet traffic. Mobile devices with limited resource capacity (i.e., computation and storage resources) and battery lifetime are experiencing technical challenges to satisfy the task requirements. Mobile edge computing (MEC) integrated with IoT applications offloads computation-intensive tasks to the MEC servers at the network edge. This technique shows remarkable potential in reducing energy consumption and delay. Furthermore, caching popular task input data at the edge servers reduces duplicate content transmission, which eventually saves associated energy and time. However, the offloaded tasks are exposed …

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‘Not Shap’D For Sportive Tricks:’ Representations Of Disability In Film And Digital Broadcast Cinema Adaptations Of Early Modern Drama, Grace Mccarthy Jan 2020

‘Not Shap’D For Sportive Tricks:’ Representations Of Disability In Film And Digital Broadcast Cinema Adaptations Of Early Modern Drama, Grace Mccarthy

Theses and Dissertations (Comprehensive)

In films that feature disability, we see the recursive and discussion-limiting impulse to say “this representation is negative. Therefore, the representation should not be seen,” based on critical theories and methodologies outside the purview of film studies. Unfortunately, the overlay of an English, narratological, sociological, or medical methodology and terminology onto a film representation of disability is ultimately recursive and self-limiting; critical and advocate calls for accuracy to the lived experience of people with disabilities in on-screen representations decline to engage with the visual construction of cinematic representations of disability and the often fascinating cinematographic and thematic patterns that emerge …

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2019 Hrs/Ehra/Aphrs/Lahrs Expert Consensus Statement On Catheter Ablation Of Ventricular Arrhythmias, Edmond M Cronin, Phillip Cuculich, Et Al. Jan 2020

2019 Hrs/Ehra/Aphrs/Lahrs Expert Consensus Statement On Catheter Ablation Of Ventricular Arrhythmias, Edmond M Cronin, Phillip Cuculich, Et Al.

2020-Current year OA Pubs

Ventricular arrhythmias are an important cause of morbidity and mortality and come in a variety of forms, from single premature ventricular complexes to sustained ventricular tachycardia and fibrillation. Rapid developments have taken place over the past decade in our understanding of these arrhythmias and in our ability to diagnose and treat them. The field of catheter ablation has progressed with the development of new methods and tools, and with the publication of large clinical trials. Therefore, global cardiac electrophysiology professional societies undertook to outline recommendations and best practices for these procedures in a document that will update and replace the …

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Reflections On Post-Bailout Policy Analysis In Ireland, Mary Murphy, John Hogan Jan 2020

Reflections On Post-Bailout Policy Analysis In Ireland, Mary Murphy, John Hogan

Articles

This short article reflects on observations from the forthcoming volume Policy Analysis in Ireland, edited by Hogan & Murphy. The volume forms part of the International Library of Policy Analysis series, which covers more than twenty countries, published by Policy Press and edited by Michael Howlett and Iris Geva-May. While various themes emerge from the Irish volume, this article focuses on only one core question: whether and how the 2008 economic crisis contracted and expanded the capacity for policy analysis in Ireland. The troika of the International Monetary Fund, European Central Bank and the European Commission are associated with policy …

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Blockchain And Insurance: A Review For Operations And Regulation, Richard Brophy Jan 2020

Blockchain And Insurance: A Review For Operations And Regulation, Richard Brophy

Articles

The purpose of this paper is to examine the operational and regulatory positions of the employment of Blockchain in the insurance industry. Blockchain technology has attracted wide interest from various stakeholders. Many theorists are predicting that this technology will disrupt financial services, including insurance. As stated that the development of blockchain is dependent on regulatory acceptance of this technology, it is essential to establish the current state of play with regard to the application and use of blockchain from a commercial and regulatory standpoints.

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Interest Rate Volatility And Macroeconomic Dynamics: Heterogeneity Matters, Michael Curran, Adnan Velic Jan 2020

Interest Rate Volatility And Macroeconomic Dynamics: Heterogeneity Matters, Michael Curran, Adnan Velic

Articles

We examine the relation between real interest rate volatility and aggregate fluctuations for a diverse sample of countries. Compiling a new dataset including emerging and advanced countries, the substantial variation in our data yields novel results: (a) stochastic volatility outperforms Markovswitching in representing interest rates, (b) some advanced economies can be more volatile than emerging markets, and (c) creditors take on more debt following volatility shocks. We show how an equilibrium business cycle model with uncertainty shocks can generate these facts. Sample heterogeneity produces significant parameter differences, playing an important role in distinguishing the effects of volatility shocks.

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Uses And Gratifications Of Generation Z Within Social Networks: A Dialectical Investigation Into The Facebook Domain, Ryan O'Carroll, Tara Rooney Jan 2020

Uses And Gratifications Of Generation Z Within Social Networks: A Dialectical Investigation Into The Facebook Domain, Ryan O'Carroll, Tara Rooney

Articles

To date, little research has considered how various types of gratifications operate within SNSs such as Facebook (LaRose et al. 2001; Quan-Haase and Young, 2010; Wang, 2015). To address this gap, we explore Generation Z’s motivational behaviour through the lens of Uses and Gratifications Theory. Additionally, we investigate the types of gratification obtained by Generation Z through Facebook. The research adopted an interpretivist philosophy and employed a qualitative approach. The data collection method used semi-structured interviews, in conjunction with qualitative digital diary research. Research participants were requested to record emotions, behaviours and opinions in their digital diaries over a consecutive …

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Exploring The Relationship Between Immigrant Enclave Theory And Transnational Diaspora Entrepreneurial Opportunity Formation, Osa Godwin Osaghae Dr, Thomas M. Cooney Jan 2020

Exploring The Relationship Between Immigrant Enclave Theory And Transnational Diaspora Entrepreneurial Opportunity Formation, Osa Godwin Osaghae Dr, Thomas M. Cooney

Articles

Immigrant Enclave Theory (IET) investigates the concentration and localisation of immigrants in a specific geographic area. Some IET studies have highlighted the resilience of these communities and described such enclaves as sources of mutual support, collective political power and beneficial social relationships. Other studies have examined the influence of IET on immigrant entrepreneurial activity within these geographic areas, although some of these studies have highlighted IET as a contributor to low profit margin businesses due to over-representation of immigrant enterprises within the same sector and geographic locality. This article considers the potential for Transnational Diaspora Entrepreneurship (TDE) as an alternative …

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Golden Parachutes And The Limits Of Shareholder Voting, Andrew C.W. Lund, Albert H. Choi, Robert Schonlau Jan 2020

Golden Parachutes And The Limits Of Shareholder Voting, Andrew C.W. Lund, Albert H. Choi, Robert Schonlau

Faculty Publications

With the passage of the Dodd-Frank Wall Street Reform and Consumer Protection Act in 2010, Congress attempted to constrain change-in-control payments (also known as “golden parachutes”) by giving shareholders the right to approve or disapprove such payments on an advisory basis. This Essay is the first to empirically examine the experience with the Say-on-Golden-Parachute (“SOGP”) vote. We find that unlike shareholder votes on proposed mergers, there is a significant amount of variation with respect to votes on golden parachutes. Notwithstanding the variation, however, the SOGP voting regime is likely ineffective in controlling golden parachute (“GP”) compensation. First, proxy advisors seem …

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Supplemental Seeding And Seed Predation In A Newly Planted Tallgrass Prairie, Isabella Betzer Jan 2020

Supplemental Seeding And Seed Predation In A Newly Planted Tallgrass Prairie, Isabella Betzer

Honors Program Theses

The Iowa around today looks vastly different from the Iowa that was originally around. What once used to house vast tallgrass prairies is now home to about 0.1% of what was originally here (Smith 1998). However, conservationists have been working hard to restore even a fraction of what originally here despite high costs and low yields in restoration prairies. Recently experiments have been done on the use of sacrificial seed to potentially increase plant yield in restoration with successful results. This study was done to further research the effects of supplemental seeding on seed predation and if seedling emergence would …

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Genetic Variation Within A Broadly Distributed Chewing Louse Genus (Thomomydoecus), Clarissa Elizabeth Bruns Jan 2020

Genetic Variation Within A Broadly Distributed Chewing Louse Genus (Thomomydoecus), Clarissa Elizabeth Bruns

Honors Program Theses

No broad study has been conducted to examine the genetics of Thomomydoecus species and their patterns of geographic variation. Chewing lice and their parasite-host relationships with pocket gophers have been studied as a key example of cophylogeny (Demastes et al., 2012). Despite this, genetic data on interspecific and intraspecific variation in Thomomydoecus is unexplored, and prior studies consisted within the narrow frame of one complex or species and its relative host gopher. This project collected, and analyzed genetic data, then generated phylogenetic trees. Many of the existing relationships between Thomomydoecus species was confirmed, and there were a number of unexpected …

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Characterization Of An Aryl Piperazine/2-Hydroxypropyl-Β-Cyclodextrin Association, A Complex With Antidiabetic Potential, R. Devine, D.S.D. Martin, Gemma Kinsella, J.B.C. Findlay, J.C. Stephens Jan 2020

Characterization Of An Aryl Piperazine/2-Hydroxypropyl-Β-Cyclodextrin Association, A Complex With Antidiabetic Potential, R. Devine, D.S.D. Martin, Gemma Kinsella, J.B.C. Findlay, J.C. Stephens

Articles

This study explores the molecular association between 4-(thiophen-2-yl)-1-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)butan-1-one (RTC1), an antidiabetic compound recently reported by our research group with challenging aqueous solubility, and 2-hydroxypropyl-β-cyclodextrin (HPBCD). The formation of a RTC1/HPBCD complex resulted in improved solubility. A phase-solubility diagram was used to determine the complex stability constant and stoichiometric ratio. 2D 1H NMR spectroscopy was utilized to study the molecular interaction between RTC1 and HPBCD in the complex. Differential scanning calorimetry and scanning electron microscopy was also employed to confirm complex formation. In vitro biological evaluation, using a glucose uptake assay, showed that the homogeneous RTC1/HPBCD complex solution showed the …

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Bioactive Indanes: Development And Validation Of An Lc-Ms/Ms Bioanalytical Method For The Determination Of Ph46a, A New Potential Anti-Inflammatory Agent, In Dog And Rat Plasma And Its Application To A Pharmacokinetic Study In Dog, Gaia Scalabrino, Tao Zhang, Neil Frankish, Helen Sheridan Jan 2020

Bioactive Indanes: Development And Validation Of An Lc-Ms/Ms Bioanalytical Method For The Determination Of Ph46a, A New Potential Anti-Inflammatory Agent, In Dog And Rat Plasma And Its Application To A Pharmacokinetic Study In Dog, Gaia Scalabrino, Tao Zhang, Neil Frankish, Helen Sheridan

Articles

A new chemical entity, which is a chiral indane dimer, PH46A, has been developed by our research group. As a clinical candidate. PH46A has recently completed Phase I clinical studies in man. Previously, during its pre-clinical development, in in vivo pre-clinical studies PH46A showed potent anti-inflammatory properties, which can be targeted at a range of diseases, including inflammatory bowel disease (IBD). To support the pre-clinical development of this drug candidate, we developed a LC MS/MS method for determining PH46 (the acid form of PH46A salt) in both dog and rat plasma using Compound 1 as internal standard (IS). Those species …

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Investigation Of A Large Gap Cold Plasma Reactor For Continuous In-Package Decontamination Of Fresh Strawberries And Spinach, Dana Ziuzina, N. N. Misra, Lu Han, Patrick J. Cullen, T. Moiseev, Jean-Paul Mosnier, K. Keener, E. Gaston, Paula Bourke Jan 2020

Investigation Of A Large Gap Cold Plasma Reactor For Continuous In-Package Decontamination Of Fresh Strawberries And Spinach, Dana Ziuzina, N. N. Misra, Lu Han, Patrick J. Cullen, T. Moiseev, Jean-Paul Mosnier, K. Keener, E. Gaston, Paula Bourke

Articles

The aim of this work was to investigate the efficacy of a large gap atmospheric cold plasma (ACP) generated with an open-air high-voltage dielectric barrier discharge (DBD) pilot-scale reactor, operated in either static (batch) or continuous mode for produce decontamination and quality retention. Significant reductions in the bacterial populations inoculated on the strawberries and spinach were obtained after the static mode of ACP treatment with 2.0 and 2.2 log10 CFU/ml reductions for E. coli and 1.3 and 1.7 log10 CFU/ml reductions for L. innocua, respectively. Continuous treatment was effective against L. innocua inoculated on strawberries, with 3.8 log10 CFU/ml …

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Bioactive Indanes: Proof Of Concept Study For Enantioselective Synthetic Routes To Ph46a, A New Potential Anti-Inflammation Agent, Tao Zhang, Gaia Scalabrino, Neil Frankish, Helen Sheridan Jan 2020

Bioactive Indanes: Proof Of Concept Study For Enantioselective Synthetic Routes To Ph46a, A New Potential Anti-Inflammation Agent, Tao Zhang, Gaia Scalabrino, Neil Frankish, Helen Sheridan

Articles

PH46A is a single enantiomer and a member of the 1,2-indane dimer family. It has two contiguous stereogenic centers with S,S configurations, one of which being a quaternary center, which has been developed as a clinical candidate for the treatment of inflammatory and autoimmune conditions. The current synthetic route to PH46A involves the generation of an unwanted enantiomer (R,R)-7, thus reducing the final yield significantly. Therefore, we have investigated potential alternatives to improve the efficiency of this synthesis. The first phase of the study has demonstrated proof of principle for a chiral alkylation of ketone 3 using phase-transfer …

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Drug Discovery: Novel Indane Scaffolds With Anticancer Activity, Vilmar Bandero, Tao Zhang, Kit Chan, Lorraine O’Driscoll, Claire Corcoran, Neil Frankish, Helen Sheridan Jan 2020

Drug Discovery: Novel Indane Scaffolds With Anticancer Activity, Vilmar Bandero, Tao Zhang, Kit Chan, Lorraine O’Driscoll, Claire Corcoran, Neil Frankish, Helen Sheridan

Articles

No abstract provided.

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Novel Mast Cell-Stabilising Amine Derivatives Of 3,4 Dihydronaphthalen-1(2h)-One And 6,7,8,9-Tetrahydro-5h-Benzo[7]Annulen-5-One, James W. Barlow, Tao Zhang, Orla Woods, Adam J. Byrne, John J. Walsh Jan 2020

Novel Mast Cell-Stabilising Amine Derivatives Of 3,4 Dihydronaphthalen-1(2h)-One And 6,7,8,9-Tetrahydro-5h-Benzo[7]Annulen-5-One, James W. Barlow, Tao Zhang, Orla Woods, Adam J. Byrne, John J. Walsh

Articles

In an investigation of 4-amino-3,4-dihydronaphthalen-1(2H)-ones as novel modulators of allergic and inflammatory phenomena, we have investigated a series of cyclic analogues. Tertiary amines of structural types 9, 10, 20 and 21 were synthesised and evaluated for mast cell stabilising activity. In vitro and in vivo studies showed that of these compounds, the cyclohexenylamino derivatives of tetralone and benzosuberone of series 20 and 21 exhibited interesting activity both in vitro and in vivo.

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N-Cyclo­Pentyl-N-(3-Oxo-2,3-Dihydro-1h-Inden-1-Yl)Acetamide, Tao Zhang, Tom Mccabe, Bartosz Marzec, Neil Frankish, Helen Sheridan Jan 2020

N-Cyclo­Pentyl-N-(3-Oxo-2,3-Dihydro-1h-Inden-1-Yl)Acetamide, Tao Zhang, Tom Mccabe, Bartosz Marzec, Neil Frankish, Helen Sheridan

Articles

The title mol­ecule, C16H19NO2, consists of an indane moiety, which is connected through an N atom to an acetamide group and a cyclo­pentane ring. The N atom adopts planar triangular geometry. Inter­molecular inter­actions, such as π–π stacking or hydrogen bonding, were not observed.

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Molecular Structure Studies Of (1s,2s)-2-Benzyl-2,3-Dihydro-2-(1hinden- 2-Yl)-1h-Inden-1-Ol, Tao Zhang, Krzysztof Paluch, Gaia Scalabrino, Neil Frankish, Anne-Marie Healy, Helen Sheridan Jan 2020

Molecular Structure Studies Of (1s,2s)-2-Benzyl-2,3-Dihydro-2-(1hinden- 2-Yl)-1h-Inden-1-Ol, Tao Zhang, Krzysztof Paluch, Gaia Scalabrino, Neil Frankish, Anne-Marie Healy, Helen Sheridan

Articles

The single enantiomer (1S,2S)-2-benzyl-2,3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol (2), has recently been synthesized and isolated from its corresponding diastereoisomer (1). The molecular and crystal structures of this novel compound have been fully analyzed. The relative and absolute configurations have been determined by using a combination of analytical tools including X-ray crystallography, X-ray Powder Diffraction (XRPD) analysis and Nuclear Magnetic Resonance (NMR) spectroscopy.

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Mast Cell Stabilisers, Tao Zhang, Deirdre Frances Finn, James William Barlow, John Jarlath Walsh Jan 2020

Mast Cell Stabilisers, Tao Zhang, Deirdre Frances Finn, James William Barlow, John Jarlath Walsh

Articles

Mast cells play a critical role in type 1 hypersensitivity reactions. Indeed, mast cell mediators are implicated in many different conditions including allergic rhinitis, conjunctivitis, asthma, psoriasis, mastocytosis and the progression of many different cancers. Thus, there is intense interest in the development of agents which prevent mast cell mediator release or which inhibit the actions of such mediators once released into the environment of the cell. Much progress into the design of new agents has been made since the initial discovery of the mast cell stabilising properties of khellin from Ammi visnaga and the clinical approval of cromolyn sodium. …

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Characterization Of Antimicrobial Effects Of Plasma-Treated Water (Ptw) Produced By Microwave-Induced Plasma (Midiplexc) On Pseudomonas Fluorescens Biofilms, Oliver Handorf, Viktoria Isabella Pauker, Thomas Weihe, Eric Freund, Sander Bekeschus, Katharina Riedel, Uta Schnabel, Jörg Ehlbeck Jan 2020

Characterization Of Antimicrobial Effects Of Plasma-Treated Water (Ptw) Produced By Microwave-Induced Plasma (Midiplexc) On Pseudomonas Fluorescens Biofilms, Oliver Handorf, Viktoria Isabella Pauker, Thomas Weihe, Eric Freund, Sander Bekeschus, Katharina Riedel, Uta Schnabel, Jörg Ehlbeck

Articles

stract: For the decontamination of surfaces in the food production industry, plasma generated compounds (PGCs) such as plasma-treated water (PTW) or plasma processed air (PPA) offer many promising possibilities for future applications. Therefore, the antimicrobial effect of water treated with microwave-induced plasma (MidiPLexc) on Pseudomonas fluorescensbiofilms was investigated. 10 ml deionized water was treated with the MidiPLexc plasma source for 100 s, 300 s and 900 s (pre-treatment time) and the bacterial biofilms were exposed to the PTW for 1 min, 3 min and 5 min (post treatment time). To investigate the influence of PTW on P. fluorescensbiofilms, microbiological assays …

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