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2020

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Articles 165841 - 165870 of 169292

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Efficacy Of The Population-Based Pilot Colorectal Cancer Screening, Csongrád County,Hungary, 2015, Mariann Rutka, Renáta Bor, Tamás Molnár, Klaudia Farkas, Anna Fábián, Márk Györffy, Anita Bálint, Ágnes Milassin, Mónika Szücs, László Tiszlavicz, Ferenc Nagy, Zoltán Szepes Jan 2020

Efficacy Of The Population-Based Pilot Colorectal Cancer Screening, Csongrád County,Hungary, 2015, Mariann Rutka, Renáta Bor, Tamás Molnár, Klaudia Farkas, Anna Fábián, Márk Györffy, Anita Bálint, Ágnes Milassin, Mónika Szücs, László Tiszlavicz, Ferenc Nagy, Zoltán Szepes

Turkish Journal of Medical Sciences

Background/aim: In Hungary, a nationwide colorectal screening program is about to be introduced in order to improve the high mortality rate of colorectal cancer (CRC). The aim was to summarize experiences from and assess short-term efficacy of the populationbased pilot colorectal screening program in 2015 in Csongrád county, Hungary. Materials and methods: Asymptomatic individuals between the ages of 50 and 70 with average risk of colorectal cancer participated in the program that was based on the two-step screening method: immune fecal blood test and colonoscopy. The short-term efficacy was assessed as the change in total CRC incidence and initial tumor …

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Which Bayley-Iii Cut-Off Values Should Be Used In Different Developmental Levels?, Peli̇n Çeli̇k, İclal Ayranci Sucakli, Hali̇l İbrahi̇m Yakut Jan 2020

Which Bayley-Iii Cut-Off Values Should Be Used In Different Developmental Levels?, Peli̇n Çeli̇k, İclal Ayranci Sucakli, Hali̇l İbrahi̇m Yakut

Turkish Journal of Medical Sciences

Background/aim: Latest version of Bayley Scales (Bayley-III) and its predecessor (BSID-II) are the most widely used standardized developmental tools in infancy and early childhood. Recent studies showed that Bayley-III scores were higher than BSID-II in 18-24 month-old and mostly premature infants. We aimed to evaluate the generalization of inflated scores of Bayley-III to children aged 6-42 months with different disease groups, and to find out which cut-off points should be used in Bayley-III to detect mild, moderate, and severe developmental delay according to BSID-II standard cut-off points. Materials and methods: Two hundred and fifty-five children aged 6-42 months with different …

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The Effects Of Blood Group Types On The Risk Of Covid-19 Infection And Its Clinical Outcome, Hakan Göker, Eli̇fcan Aladağ Karakulak, Haluk Demi̇roğlu, Çağlayan Merve Ayaz Ceylan, Yahya Büyükaşik, Ahmet Çağkan İnkaya, Salih Aksu, Ni̇lgün Sayinalp, İbrahi̇m Celaletti̇n Haznedaroğlu, Ömrüm Uzun, Murat Akova, Osman İlhami̇ Özcebe, Serhat Ünal Jan 2020

The Effects Of Blood Group Types On The Risk Of Covid-19 Infection And Its Clinical Outcome, Hakan Göker, Eli̇fcan Aladağ Karakulak, Haluk Demi̇roğlu, Çağlayan Merve Ayaz Ceylan, Yahya Büyükaşik, Ahmet Çağkan İnkaya, Salih Aksu, Ni̇lgün Sayinalp, İbrahi̇m Celaletti̇n Haznedaroğlu, Ömrüm Uzun, Murat Akova, Osman İlhami̇ Özcebe, Serhat Ünal

Turkish Journal of Medical Sciences

Background/aim: COVID-19 (Coronavirus disease of 2019) is an infectious disease outbreak later on declared as a pandemic, caused by the SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2). It spreads very rapidly and can result in severe acute respiratory failure. The clinical studies have shown that advanced age and chronic diseases increase the risk of infection. However, influence of the blood groups on COVID-19 infection and its outcome remains to be confirmed. The aim of this study is to investigate whether there exists a relationship between the blood groups of the patients and risk of SARS-CoV-2 infection and the clinical outcomes in …

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The Needle Electromyography Findings In The Neurophysiological Classification Of Ulnar Neuropathy At The Elbow, Hali̇t Fi̇danci, İlker Öztürk, Ahmet Candan Köylüoğlu, Mehmet Yildiz, Şencan Buturak, Zülfi̇kar Arlier Jan 2020

The Needle Electromyography Findings In The Neurophysiological Classification Of Ulnar Neuropathy At The Elbow, Hali̇t Fi̇danci, İlker Öztürk, Ahmet Candan Köylüoğlu, Mehmet Yildiz, Şencan Buturak, Zülfi̇kar Arlier

Turkish Journal of Medical Sciences

Background/aim: Although ulnar neuropathy at the elbow (UNE) is the second most common entrapment mononeuropathy, there are few reports on its neurophysiological classification. In this study, we tried to find out the role of needle electromyography (EMG) in the neurophysiological classification of UNE. Materials and methods: UNE patients who met the clinical and neurophysiological diagnostic criteria and healthy individuals were included in this study. Reference values of nerve conduction studies were obtained from healthy individuals. Needle EMG was performed to all UNE patients. According to the neurophysiological classification proposed by Padua, UNE patients were classified as mild, moderate, and severe. …

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Clinical Characteristics And Long-Term Outcome Of Takayasu Arteritisin Iran: A Multicentre Study, Aida Malek Mahdavi, Nadereh Rashtchizadeh, Hadiseh Kavandi, Mehrzad Hajialilo, Sousan Kolahi, Mohammad-Reza Nakhjavani, Ali-Asghar Ebrahimi, Seyedmostafa Seyedmardani, Mansour Salesi, Mohsen Soroush, Alireza Khabbazi Jan 2020

Clinical Characteristics And Long-Term Outcome Of Takayasu Arteritisin Iran: A Multicentre Study, Aida Malek Mahdavi, Nadereh Rashtchizadeh, Hadiseh Kavandi, Mehrzad Hajialilo, Sousan Kolahi, Mohammad-Reza Nakhjavani, Ali-Asghar Ebrahimi, Seyedmostafa Seyedmardani, Mansour Salesi, Mohsen Soroush, Alireza Khabbazi

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the demographic, clinical, angiographic and prognostic characteristics of Takayasu arteritis (TA) in Iran. Materials and methods: A total of 75 patients with TA based on the American College of Rheumatology 1990 criteria for TA classification referred to the Rheumatology Centres, were followed-up from 1989 to 2019. Demographic, clinical, angiographic and prognostic characteristics were collected at baseline and last visit. Results: The mean age was 31.9 ± 9.8 years at the disease onset. Female to male ratio was 14. The median latency in diagnosis was 24 months. Pulse discrepancy in the arms, blood pressure discrepancy …

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Thiol/Disulphide Homeostasis In Intensive Care Unit Patients With Sepsis And Septic Shock, Hami̇t Yildiz Jan 2020

Thiol/Disulphide Homeostasis In Intensive Care Unit Patients With Sepsis And Septic Shock, Hami̇t Yildiz

Turkish Journal of Medical Sciences

Background/aim: Sepsis is a condition caused by infection followed by unregulated inflammatory response which may lead to organ dysfunction. The aim of this study is to be the first in the literature and it has been designed to show the thiol/disulphide changes in patients with sepsis and septic shock and their correlation with acute phase reactants. Material and methods: A total of 113 patients (septic shock 53 and sepsis 60) and 60 healthy control subjects have been enrolled in this study from the period February 2018 to 2019. The patients were divided in 2 groups: nonsurvivors (74) and survivors (39). …

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Are Clinicians Successful In Diagnosing Cutaneous Adnexal Tumors? A Retrospective, Clinicopathological Study, Melek Aslan Kayiran, Ayşe Serap Karadağ, Yasi̇n Küçük, Bengü Çobanoğlu Şi̇mşek, Vefa Asli Erdemi̇r, Necmetti̇n Akdeni̇z Jan 2020

Are Clinicians Successful In Diagnosing Cutaneous Adnexal Tumors? A Retrospective, Clinicopathological Study, Melek Aslan Kayiran, Ayşe Serap Karadağ, Yasi̇n Küçük, Bengü Çobanoğlu Şi̇mşek, Vefa Asli Erdemi̇r, Necmetti̇n Akdeni̇z

Turkish Journal of Medical Sciences

Background/aim: Cutaneous adnexal tumors (CAT) are rare tumors originating from the adnexal epithelial parts of the skin. Due to its clinical and histopathological characteristics comparable with other diseases, clinicians and pathologists experience difficulties in its diagnosis. We aimed to reveal the clinical and histopathological characteristics of the retrospectively screened cases and to compare the prediagnoses and histopathological diagnoses of clinicians. Materials and methods: The data of the last 5 years were scanned and patients with histopathological diagnosis of CAT were included in the study. Results: A total of 65 patients, including 39 female and 26 male patients aged between 8 …

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Should The Dose Of Levothyroxine Be Changed In Hypothyroidism Patients Fasting Duringramadan?, Arzu Or Koca, Murat Dağdevi̇ren, Mustafa Altay Jan 2020

Should The Dose Of Levothyroxine Be Changed In Hypothyroidism Patients Fasting Duringramadan?, Arzu Or Koca, Murat Dağdevi̇ren, Mustafa Altay

Turkish Journal of Medical Sciences

Background/aim: Muslims worship by fasting from predawn (suhoor) until sunset (iftar) for 30 days in the religious month of Ramadan. In addition to prolonged hunger, patients fasting with a diagnosis of hypothyroidism take their doses of levothyroxine (LT4) outside of daytime fasting hours. The purpose of our study is to compare the values of hypothyroid patients which have been obtained through thyroid function tests before and after Ramadan. Materials and methods: Ninety-seven patients; ranging from 18 to 65 years old, who were followed with a diagnosis of hypothyroidism, who fasted during Ramadan, and who had no change of their LT4 …

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Validity And Reliability Of The Turkish Version Of The Michigan Neuropathy Screeninginstrument, Duygu Aktar Reyhani̇oğlu, Süleyman Cem Adiyaman, Murat Bektaş, Onur Bulut, Başak Özgen Saydam, Firat Bayraktar, Bi̇lge Kara Jan 2020

Validity And Reliability Of The Turkish Version Of The Michigan Neuropathy Screeninginstrument, Duygu Aktar Reyhani̇oğlu, Süleyman Cem Adiyaman, Murat Bektaş, Onur Bulut, Başak Özgen Saydam, Firat Bayraktar, Bi̇lge Kara

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to demonstrate the validity and reliability of the Turkish version of the Michigan Neuropathy Screening Instrument (MNSI-TR). Materials and methods: The study included 127 patients aged 45-76 years who were previously diagnosed with type 1 or 2 diabetes. Stability of the instrument was assessed by intraclass correlation coefficient. Reliability of the MNSI-TR was assessed using the Kuder- Richardson formula 20 test, item-total correlations, and floor/ceiling effect. Validity was evaluated with receiver operating characteristic curve analysis. A logistic regression model was used to determine to what degree the MNSI-TR explain nerve conduction study (NCS) …

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Relationship Between Helicobacter Pylori Infection And Pityriasis Versicolor:Can Helicobacter Pylori Infection Be A New Etiologic Factor For Pityriasis Versicolor?, Ömer Kutlu, Zeynal Doğan, Hati̇ce Meral Ekşi̇oğlu, Murat Keki̇lli̇ Jan 2020

Relationship Between Helicobacter Pylori Infection And Pityriasis Versicolor:Can Helicobacter Pylori Infection Be A New Etiologic Factor For Pityriasis Versicolor?, Ömer Kutlu, Zeynal Doğan, Hati̇ce Meral Ekşi̇oğlu, Murat Keki̇lli̇

Turkish Journal of Medical Sciences

Background/aim: H. pylori has been found to be related to certain dermatological diseases. However, there is no data as yet to propose an association between H. pylori and pityriasis versicolor. In this study, we aimed to evaluate the association between H. pylori and pityriasis versicolor. Materials and methods: This was a prospective study performed in the Gastroenterology and Dermatology and Venereology departments of the Health Sciences University, Ankara Training and Research Centre. A total of 57 consecutive patients (27 pityriasis versicolor, 30 telogen effluvium) were enrolled from the Department of Dermatology and Venereology. All patients were screened for H. pylori …

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Body Awareness And Chronic Low Back Pain: Validity And Reliability Study Of Turkish Version Of Body Awareness Rating Scale, Aynur Demi̇rel, Di̇lara Onan, Yasemi̇n Özel Asliyüce, Müzeyyen Öz, Utku Berberoğlu, Özlem Ülger Jan 2020

Body Awareness And Chronic Low Back Pain: Validity And Reliability Study Of Turkish Version Of Body Awareness Rating Scale, Aynur Demi̇rel, Di̇lara Onan, Yasemi̇n Özel Asliyüce, Müzeyyen Öz, Utku Berberoğlu, Özlem Ülger

Turkish Journal of Medical Sciences

Background/aim: Previous studies reported that patients with chronic low back pain (CLBP) had trouble describing senses or body functions. A questionnaire, the body awareness rating questionnaire (BARQ), was recently developed for assessing body awareness. The aim of the study was to develop a Turkish version of the BARQ and investigate the validity and reliability in patients with CLBP. Materials and methods: BARQ translated to Turkish with forward-backward method. Ninety-nine patients with CLBP and 101 healthy controls (HC) completed the BARQ-T. Fifty-one of patients with CLBP and HC repeated BARQ-T 3 days later. In addition to BARQ-T, Oswestry disability index (ODI), …

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Surgical Considerations And Audiological Results Of Cochlear Implantation In Patients With Otosclerosis, Tolgahan Çatli, Taşkin Tokat, Ergül Başaran Bozkurt, Zehra Hi̇lal Adibelli̇, Uğurtan Ergün, Enver Altaş, Levent Olgun Jan 2020

Surgical Considerations And Audiological Results Of Cochlear Implantation In Patients With Otosclerosis, Tolgahan Çatli, Taşkin Tokat, Ergül Başaran Bozkurt, Zehra Hi̇lal Adibelli̇, Uğurtan Ergün, Enver Altaş, Levent Olgun

Turkish Journal of Medical Sciences

Background/aim: To emphasize the role of cochlear implantation (CI) in the auditory rehabilitation of patients with otosclerosis (OS) and share our surgical experiences on this rare group of patients. Materials and methods: Retrospective analysis of the patients who have a diagnosis of otosclerosis and implanted between January 1998-May 2019 was performed. Preoperative and postoperative clinical, radiological, audiological and surgical findings are presented. Results: Among 2195 patients who have been implanted in our institution, 12 (0.54%) met the diagnostic criteria of OS according to their preoperative (clinical, radiological, audiological) and peroperative (surgical) findings. Electrode insertion was performed via "round window membrane …

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The Effect Of Iatrogenic Subclinical Hyperthyroidism On Anxiety, Depression And Quality Of Life In Differentiated Thyroid Carcinoma, Nazli Gülsoy Kirnap, Özlem Turhan İyi̇di̇r, Yusuf Bozkuş, Şeri̇fe Mehli̇ka Işildak, Cüneyd Anil, Sevde Nur Firat, Canan Demi̇r, Asli Nar, Nesli̇han Başçil Tütüncü Jan 2020

The Effect Of Iatrogenic Subclinical Hyperthyroidism On Anxiety, Depression And Quality Of Life In Differentiated Thyroid Carcinoma, Nazli Gülsoy Kirnap, Özlem Turhan İyi̇di̇r, Yusuf Bozkuş, Şeri̇fe Mehli̇ka Işildak, Cüneyd Anil, Sevde Nur Firat, Canan Demi̇r, Asli Nar, Nesli̇han Başçil Tütüncü

Turkish Journal of Medical Sciences

Background/aim: Overt thyroidism is known to cause neuropsychiatric disorders but studies on subclinical hyperthyroidism (SCH) are limited. Subclinical hyperthyroidism induction by administering L-Thyroxine (LT4) is the standard treatment method in differentiated thyroid carcinoma (DTC) follow-up. Our aim was to investigate whether anxiety, depression and quality of life are affected in DTC patients followed-up with exogenous SCH. Materials and methods: The patients were divided into exogenous SCH by LT4-DTC (n = 127), euthyroid-DTC (n = 66) and exogenous euthyroid-benign thyroid noduüle (BTN) who underwent thyroidectomy for benign thyroid pathology (n = 85) groups. Results: The rate of moderate/severe anxiety was significantly …

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The Assessment Of Skin Sebum And Moisture Content Of Infants With Atopic Dermatitis, Hati̇ce Güneş, Hülya Nazi̇k, Mehmet Yaşar Özkars, Nurgül Parlak, Ayten Yildiz, Ömer Duyuran, Bahaüddi̇n Ahmed Yalçin Jan 2020

The Assessment Of Skin Sebum And Moisture Content Of Infants With Atopic Dermatitis, Hati̇ce Güneş, Hülya Nazi̇k, Mehmet Yaşar Özkars, Nurgül Parlak, Ayten Yildiz, Ömer Duyuran, Bahaüddi̇n Ahmed Yalçin

Turkish Journal of Medical Sciences

Background/aim: Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterized by dry skin, pruritus and eczematous lesions. The aim of this study is to evaluate the skin moisture and sebum content of the infants with AD and its relationship between the disease severity. Materials and methods: For this cross-sectional and case-control study we included 49 infants with AD aged between 2 and 24 months and 34 healthy infants with the same age and sex as a control group. Skin moisture and sebum content were measured by the bio- impedance method and recorded. Skin prick tests, total IgE levels and …

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The Association Between The Route Of Nutrition And Serum Levels Of Adipokines In Critical Illness: A Pilot Study, Kürşat Gündoğan, Ender Doğan, Nurhayat Tuğra Özer, Gülşah Güneş Şahi̇n, Serap Şahi̇n, Murat Sungur, İsmai̇l Hakki Akbudak, Sabahatti̇n Muhtaroğlu, Muhammet Güven, Thomas R. Ziegler Jan 2020

The Association Between The Route Of Nutrition And Serum Levels Of Adipokines In Critical Illness: A Pilot Study, Kürşat Gündoğan, Ender Doğan, Nurhayat Tuğra Özer, Gülşah Güneş Şahi̇n, Serap Şahi̇n, Murat Sungur, İsmai̇l Hakki Akbudak, Sabahatti̇n Muhtaroğlu, Muhammet Güven, Thomas R. Ziegler

Turkish Journal of Medical Sciences

Background/aim: Adipokines play an important role in the regulation of metabolism. In critical illness, they alter serum levels and are suspected to worsen clinical outcomes. But the effect of the route of nutrition on adipokines is not known. The purpose of this study was to evaluate the association between the route of nutrition and adipokine levels in critically ill patients. Materials and methods: This prospective study was performed in an intensive care unit (ICU). Patients admitted to the ICU for least 72 h and receiving either enteral nutrition (EN) via tube feeding or parenteral nutrition (PN) were enrolled. Serum was …

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Subclinical Cardiac Structural And Electrical Abnormalities In Fibromyalgia Syndrome, Ekrem Aksu, Ejder Berk, Abdullah Sökmen, Güli̇zar Sökmen, Enes Çeli̇k Jan 2020

Subclinical Cardiac Structural And Electrical Abnormalities In Fibromyalgia Syndrome, Ekrem Aksu, Ejder Berk, Abdullah Sökmen, Güli̇zar Sökmen, Enes Çeli̇k

Turkish Journal of Medical Sciences

Background/aim: In the literature, there is a paucity of data about the effects of fibromyalgia syndrome (FMS) on myocardial function and electrophysiological properties of atrium and ventricles. In this study, we investigated cardiac functions and noninvasive predictors of arrhythmias in patients with FMS. Materials and methods: The study included 43 female patients diagnosed with FMS and 30 age- and sex-matched healthy subjects. The presence of fragmented QRS (fQRS) morphology, P dispersion, QT dispersion, inter- and intraatrial electromechanical delay was evaluated in the groups with 12-lead ECG and standard and tissue Doppler echocardiography. Results: Among electrocardiographic parameters, P dispersion, QT dispersion, …

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Reliability And Validity Of The Turkish Version Of The Vocal Fatigue Index, Seher Şi̇ri̇n, Mehmet Fati̇h Öğüt, Cem Bi̇lgen Jan 2020

Reliability And Validity Of The Turkish Version Of The Vocal Fatigue Index, Seher Şi̇ri̇n, Mehmet Fati̇h Öğüt, Cem Bi̇lgen

Turkish Journal of Medical Sciences

Background/aim: The aim of this study is to evaluate the reliability and validity of the Turkish version of the Vocal Fatigue Index (VFI). Materials and methods: The study was conducted with 535 participants including 285 patients with voice disorders and 250 healthy controls. Internal consistency and test-retest reliability were calculated for the reliability analysis. The mean VFI factor scores of both groups were compared. The strength and direction of the relation between VFI and Voice-Related Quality of Life (V-RQOL) measure was evaluated for the validity analysis. Results: The Cronbach's alpha coefficient of VFI factor scores was found to be 0.920 …

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Preoperative Estimation Of Breast Resection Weight In Patients Undergoing Inferior Pedicle Reduction Mammoplasty: The Bilgen Formula, Fatma Bi̇lgen, Alper Ural, Mehmet Bekereci̇oğlu Jan 2020

Preoperative Estimation Of Breast Resection Weight In Patients Undergoing Inferior Pedicle Reduction Mammoplasty: The Bilgen Formula, Fatma Bi̇lgen, Alper Ural, Mehmet Bekereci̇oğlu

Turkish Journal of Medical Sciences

Background/aim: Symptomatic breast hypertrophy has a significant impact on the quality of life of women. The amount of tissue to be excised may be preoperatively estimated by an experienced surgeon. However, this remains a subjective assessment. Accurate quantification of the amount of breast tissue to be resected in the preoperative period will be a guide for both patient information and the surgeon during the operation. The aim of this study is to develop a new method based on simple measurements that can accurately estimate the resection weight in the preoperative period in a wide range of patients undergoing reduction mammoplasty. …

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Comparing The Complications Of Laparoscopically Performed Simple, Radical And Donor Nephrectomy, Erkan Ölçücüoğlu Jan 2020

Comparing The Complications Of Laparoscopically Performed Simple, Radical And Donor Nephrectomy, Erkan Ölçücüoğlu

Turkish Journal of Medical Sciences

Bacground/aim: The aim of this study was to compare the complications of laparoscopic simple, radical and donor nephrectomies performed in a single center. Materials and methods: The study was conducted on 392 patients who underwent laparoscopic nephrectomy in University of Health Sciences, Ankara Türkiye Yüksek İhtisas Training and Research Hospital between January 1, 2008 and January 30, 2019. Clinical and laboratory parameters were recorded. Postoperative complications were recorded and graded as per Clavien-Dindo classification (CDC). All analyses were performed on SPSS v21.0 (IBM Corp., Armonk, NY, USA). Results: The mean age of the patients was 49.13 ± 15.45 years. The …

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Effects Of Different Analgesic Methods Used For Vaginal Delivery On Mothers And Fetuses, Gülçi̇n Babaoğlu, Banu Kiliçaslan, Aysun Ankay Yilbaş, Bi̇lge Çelebi̇oğlu Jan 2020

Effects Of Different Analgesic Methods Used For Vaginal Delivery On Mothers And Fetuses, Gülçi̇n Babaoğlu, Banu Kiliçaslan, Aysun Ankay Yilbaş, Bi̇lge Çelebi̇oğlu

Turkish Journal of Medical Sciences

Background/aim: Knowledge regarding pain relief during labor remains insufficient. We aimed to determine and compare the effectiveness and safety of epidural analgesia, combined spinal-epidural analgesia, and parenteral meperidine on both mothers and fetuses. Materials and methods: This study was designed as an observational case-control study. We collected prospective data from patients whose labor pain management was conducted with meperidine in addition to retrospective cohort data of neuraxial methods; 138 patients were enrolled. Epidural analgesia group consisted of 68 patients, whereas combined spinal-epidural (CSE) analgesia group and meperidine group consisted of 50 and 20 patients, respectively. We compared the delivery patterns, …

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The Profitmap-Neck - A Questionnaire For Measuring Symptoms And Functional Limitations In Neck Pain: Reliability, Validity And Cross-Cultural Adaptation Of The Turkish Version, Hati̇ce Çeti̇n, Nezi̇re Köse, Sevi̇l Bi̇lgi̇n, Haluk Tekerlek, Esra Dülger, Ceyhun Türkmen, Jale Karakaya Jan 2020

The Profitmap-Neck - A Questionnaire For Measuring Symptoms And Functional Limitations In Neck Pain: Reliability, Validity And Cross-Cultural Adaptation Of The Turkish Version, Hati̇ce Çeti̇n, Nezi̇re Köse, Sevi̇l Bi̇lgi̇n, Haluk Tekerlek, Esra Dülger, Ceyhun Türkmen, Jale Karakaya

Turkish Journal of Medical Sciences

Background/aim: The Profile Fitness Mapping neck questionnaire (ProFitMap-neck) is a reliable and valid assessment instrument for measuring neck-related symptoms and functional limitations in people with neck pain, but a Turkish version of it had not been published. The purpose of this study was to investigate the adaptation, validity, and intrarater reliability of the Turkish version of the ProFitMap-neck. Materials and methods: Two hundred and thirty-five individuals with chronic neck pain were enrolled in the study. Intrarater reliability was assessed by intraclass correlation coefficient (ICC) and Cronbach's alpha was calculated for internal consistency. For concurrent validity, ProFitMap-neck scores were compared with …

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Factors Associated With Severe Lung Disease In An Adult Population With Cystic Fibrosis: A Single-Center Experience, Berri̇n Er, Ebru Çelebi̇oğlu, Ebru Yalçin, Deni̇z Doğru, Özlem Erden Aki̇, Ömrüm Uzun, Murat Akova, Uğur Özçeli̇k, Nural Ki̇per, Sali̇h Emri̇ Jan 2020

Factors Associated With Severe Lung Disease In An Adult Population With Cystic Fibrosis: A Single-Center Experience, Berri̇n Er, Ebru Çelebi̇oğlu, Ebru Yalçin, Deni̇z Doğru, Özlem Erden Aki̇, Ömrüm Uzun, Murat Akova, Uğur Özçeli̇k, Nural Ki̇per, Sali̇h Emri̇

Turkish Journal of Medical Sciences

Background/Aim: The patients with cystic fibrosis (CF) are living longer compared to the past, but respiratory failure is still the most common cause of mortality. The aim of this study is to investigate factors associated with severe lung disease in a cohort of adult patients with CF. Materials and methods: Demographic data, clinical and laboratory findings of the patients aged 18 years and more were collected and the patients were grouped according to forced expiratory volume in 1 s (FEV1) as severe group:

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Validating The Turkish Version Of The Weinstein Noise Sensitivity Scale: Effects Of Age, Sex, And Education Level, Meli̇s Keski̇n Yildiz, Yusuf Kemal Kemaloğlu, Yetki̇n Tuaç, Güven Mengü, Recep Karamert, Çağil Gökdoğan Jan 2020

Validating The Turkish Version Of The Weinstein Noise Sensitivity Scale: Effects Of Age, Sex, And Education Level, Meli̇s Keski̇n Yildiz, Yusuf Kemal Kemaloğlu, Yetki̇n Tuaç, Güven Mengü, Recep Karamert, Çağil Gökdoğan

Turkish Journal of Medical Sciences

Background/aim: Subjective noise sensitivity (SNS) is not only one of the most important predictors of perceived noise annoyance for the subjects exposed to the noise, but also strongly related with some psychological conditions and poor health perception of the subjects. Weinstein's Noise Sensitivity Scale (WNSS) is widely used for measuring of SNS. Materials and methods: In this study we adapted WNSS to Turkish (Tr-WNSS) and evaluated its psychometric properties and effect of age, sex and education level on SNS. Results: The study included 105 males and 105 female subjects between 18 and 55 years of age. Conclusion: Our data demonstrated …

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Risk Indices That Predict In-Hospital Mortality Of Elderly Patients, Di̇lek Dülger, Özgür Albuz Jan 2020

Risk Indices That Predict In-Hospital Mortality Of Elderly Patients, Di̇lek Dülger, Özgür Albuz

Turkish Journal of Medical Sciences

Background/aim: Mortality in the elderly population tends to be higher than in all other age groups; the risk factors that predict mortality among those in this age cohort are not fully understood. This large-scale clinical study aimed to identify effective risk factors that predict mortality in the elderly population with a particular focus on age and hospitalization status. Material and methods: We retrospectively analyzed outcomes from patients with clinical follow-up between July 2015 and January 2020 at 29 Mayıs State Hospital, Ankara, Turkey. Patient records with missing or ambiguous data were excluded. Age, sex, length of hospital stay, comorbidities, consultation …

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The Effect Of Sacrospinous Ligament Fixation During Vaginal Hysterectomy On Postoperative De Novo Stress Incontinence Occurrence: A Prospective Study With 2-Year Follow-Up, Eralp Başer, Kerem Doğa Seçki̇n, Pinar Kadi̇roğullari, Hüseyi̇n Kiyak Jan 2020

The Effect Of Sacrospinous Ligament Fixation During Vaginal Hysterectomy On Postoperative De Novo Stress Incontinence Occurrence: A Prospective Study With 2-Year Follow-Up, Eralp Başer, Kerem Doğa Seçki̇n, Pinar Kadi̇roğullari, Hüseyi̇n Kiyak

Turkish Journal of Medical Sciences

Background/aim: To investigate the risk of de novo stress urinary incontinence (SUI) occurrence in women who were treated for pelvic organ prolapse (POP) with sacrospinous ligament fixation (SSLF) in addition to vaginal hysterectomy (VAH) and antero-posterior colporrhaphy (CAP) over a 24-month follow-up period. Materials and methods: A prospective randomized study was designed. Women without occult or obvious SUI were randomized into either one of the study groups: Group 1: VAH + CAP, and Group 2: VAH + CAP + SSLF. Postoperatively, the patients were reevaluated for de novo SUI occurrence. Results: A total of 150 women were analyzed [G1 = …

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Evaluation Of The Effects Of Ss1-Selective Beta-Blockers On Bone Mineral Density And Fracture Risk In Postmenopausal Women, Betül Yavuz Keleş, Meltem Vural, Burcu Önder, Kadri̇ye Öneş Jan 2020

Evaluation Of The Effects Of Ss1-Selective Beta-Blockers On Bone Mineral Density And Fracture Risk In Postmenopausal Women, Betül Yavuz Keleş, Meltem Vural, Burcu Önder, Kadri̇ye Öneş

Turkish Journal of Medical Sciences

Background/aim: ß1-selective beta-blockers (BBs) are sympatholytic agents, and discerning their effects on bone health would be of great importance. This study aimed to investigate the influence of ß1-selective BBs on bone mineral density (BMD) and fracture risk. Materials and methods: This study included postmenopausal women who used ß1-selective BBs (BB group) and control group. Sociodemographic characteristics, BMD and previous fragility fractures were recorded. Additionally, the 10-year probability of a major osteoporotic and hip fracture was calculated using the fracture risk assessment tool (FRAX). Results: A total of 60 participants were included in the study. L1-4 and L2-4 BMD values were …

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Evaluation Of The Cardioprotective Effects Of Crystalloid Del Nido Cardioplegia Solution Via A Rapid And Accurate Cardiac Marker: Heart-Type Fatty Acid-Binding Protein, Mehmet Ki̇ri̇şci̇, Aydemi̇r Koçarslan, Duygun Altintaş Aykan, Fi̇li̇z Alkan Baylan, Adem Doğaner, Yavuz Orak Jan 2020

Evaluation Of The Cardioprotective Effects Of Crystalloid Del Nido Cardioplegia Solution Via A Rapid And Accurate Cardiac Marker: Heart-Type Fatty Acid-Binding Protein, Mehmet Ki̇ri̇şci̇, Aydemi̇r Koçarslan, Duygun Altintaş Aykan, Fi̇li̇z Alkan Baylan, Adem Doğaner, Yavuz Orak

Turkish Journal of Medical Sciences

Background/aim: Our aim in this study was to compare the efficacy and safety of crystalloid del Nido solution and cold blood cardioplegia solution on clinical and laboratory parameters. Materials and methods: Sixty patients who underwent elective coronary bypass operation between July 2019 and January 2020 were included in our study. Patients were divided into 2 groups of 30 patients using del Nido solution (DNS) and cold blood cardioplegia solution (CBCS), which were given for cardiac arrest. Demographic data, preoperative, postoperative 0th h, 6th h and 4th day creatine kinase myocardial band (CK-MB) and troponin I values were compared with a …

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Spectrum Of Germline Cancer Susceptibility Gene Mutations In Turkish Colorectal Cancer Patients: A Single Center Study, Haktan Bağiş Erdem, Taha Bahsi̇ Jan 2020

Spectrum Of Germline Cancer Susceptibility Gene Mutations In Turkish Colorectal Cancer Patients: A Single Center Study, Haktan Bağiş Erdem, Taha Bahsi̇

Turkish Journal of Medical Sciences

Background/aim: Quarter of colorectal cancer patients have a family history and 6% of these comprise hereditary cancer syndromes. For developing national health strategies for genetic screening, it is crucial to determine the spectrum of damaging alterations in causative genes and to describe frequent founder mutations. Materials and methods: One hundred and thirty six unrelated colorectal cancer cases were investigated. Qiagen large hereditary cancer panel and Hereditary Cancer Solution v1.1 panel were used for sequencing. The sequencing process was performed on the Illumina MiSeq system. The data analyses were performed on QIAGEN Clinical Insight (QCITM) Analyze software and Sophia DDM software. …

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The Relationship Of The Immune Response Mediator Genes' Polymorphic Variants With The Methotrexate Efficacy In Juvenile Idiopathic Arthritis, Liliia Nazarova, Ksenia Danilko, Viktor Malievsky, Denis Karimov, Akhat Bakirov, Tatiana Viktorova Jan 2020

The Relationship Of The Immune Response Mediator Genes' Polymorphic Variants With The Methotrexate Efficacy In Juvenile Idiopathic Arthritis, Liliia Nazarova, Ksenia Danilko, Viktor Malievsky, Denis Karimov, Akhat Bakirov, Tatiana Viktorova

Turkish Journal of Medical Sciences

Background/aim: The aim of the study was to analyze the relationship of the immune response mediator genes' polymorphic loci (TNFA rs1800629, LTA rs909253, IL1B rs16944, IL2-IL21 rs6822844, IL2RA rs2104286, IL6 rs1800795, IL10 rs1800872, MIF rs755622, CTLA4 rs3087243, NFKB1 rs28362491, PTPN22 rs2476601, PADI4 rs2240336) variants with the methotrexate efficacy in juvenile idiopathic arthritis (JIA). Materials and methods: The study included 274 JIA patients from the Republic of Bashkortostan, Russia. Achieving the American College of Rheumatology Pediatric 30 (ACR Pedi 30) response was regarded as the presence of the response to methotrexate (otherwise, as the absence), while achieving clinical remission on medication …

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Optimization Of Isothermal Amplification Method For Mycobacterium Tuberculosis Detection And Visualization Method For Fieldwork, Hati̇ce Esra Ağel, Hasan Sağcan, İsmai̇l Ceyhan, Riza Durmaz Jan 2020

Optimization Of Isothermal Amplification Method For Mycobacterium Tuberculosis Detection And Visualization Method For Fieldwork, Hati̇ce Esra Ağel, Hasan Sağcan, İsmai̇l Ceyhan, Riza Durmaz

Turkish Journal of Medical Sciences

Background/aim: Tuberculosis is still one of the most contagious diseases around the world. Key factors of tuberculosis control are rapid diagnostic, efficient treatment, and prevention of contamination by surveillance and monitoring. However, culture is the gold standard method for laboratory diagnosis of tuberculosis; the results are several weeks to obtain. In order to prevent contamination of tuberculosis, diagnosis must be made in short time and treatment should be started as soon as possible. The aim of this study is to optimize the loop-mediated isothermal amplification (LAMP) method, which provides a much faster and more sensitive result than the polymerase chain …

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