Digital Commons Network^™

Evaluating Flow Features For Network Application Classification, Carlos Alcantara

Open Access Theses & Dissertations

Communication networks provide the foundational services on which our modern economy depends. These services include data storage and transfer, video and voice telephony, gaming, multimedia streaming, remote invocation, and the world wide web. Communication networks are large-scale distributed systems composed of heterogeneous equipment. As a result of scale and heterogeneity, communication networks are cumbersome to manage (e.g., configure, assess performance, detect faults) by human operators. With the emergence of easily accessible network data and machine learning algorithms, there is a great opportunity to move network management towards increasing automation. Network management automation will allow for a reduced likelihood of human …

The Effect Of Waterpipe/Hookah On Platelet Function And The Impact Of Inhibition Of Gβγ Subunits On Hemostasis And Thrombogenesis, Ahmed Alarabi

Open Access Theses & Dissertations

Abstract (Hookah)

Cardiovascular diseases (CVD’s) is a major public health problem. Among CVD’s risk factors, tobacco smoking is considered the single most preventable cause of death, with thrombosis being the main mechanism of CVD’s mortality in smokers. While tobacco smoking has been on the decline, the use of waterpipe/hookah has been rising, mainly due to the perception that they are “less harmful” than regular cigarettes. Strikingly, there are few studies on the negative effects of waterpipes on the cardiovascular system, and none regarding their direct contribution to thrombus formation. We employed a waterpipe whole-body exposure protocol that mimics real‐life human …

Does The Type Of Housing A Child Lives In Predict Blood Lead Level?, Elizabeth Alvarado Navarro

Open Access Theses & Dissertations

Background and Significance: Childhood lead exposure continues to be a global health problem that can compromise children's long-term health. Identifying factors that predict which children may be at the highest risk of exposure is a strategy that could help focus child lead surveillance. Lead is a natural element found in small amounts in the earth's crust and has been widely used in industry and consumer products since the time of the Romans. Lead, however, is highly toxic for humans and serves no biological purpose in the human body. There is substantial evidence that, even at the lowest levels of exposure, …

Lévy Processes: Characterizing Volcanic And Financial Time Series, Peter Kwadwo Asante

Open Access Theses & Dissertations

In this work, we use the Diffusion Entropy Analysis (DEA) to analyze and detect the scaling properties of time series from both emerging and well established markets as well as volcanic eruptions recorded by a seismic station, both financial and volcanic time series data are known to have high frequencies (i.e they are collected at an extremely fine scale). The objective is to determine the characterization i.e whether they follow a Gaussian or Lévy distribution. If they do follow a Lévy distribution we are then interested in finding if they are characterized by a Lévy walk which has a finite …

A Survey Of The Current State Of The Practice In Bridging The Gap Between Engineering Ontologies And Modeling Profiles For Engineering Applications, John Artus

Open Access Theses & Dissertations

Model-Based Systems Engineering holds the promise of enhancing systems engineering tasks and product quality through better, more efficient exchange of data across tools, personnel, and departments, a higher quality of analysis resulting from greater access to cross-discipline data, better coordination between engineering activities and those of program management, and many other benefits. Yet, there is still no standardized method for achieving commonality of architecture vocabulary across projects, across, companies, across industries such that entities operating in the same domain produce products that speak the same technical language. Some specialized domains, such as the Department of Defense (DoD), have developed Architecture …

Fabrication, Development, And Characterization Of Hipco Swcnt - Alginate Hydrogel Composites For Cellular Product Applications, Fabian Armando Alvarez-Primo

Open Access Theses & Dissertations

In this study, we designed, synthesized, and characterized ultrahigh purity single-walled carbon nanotube (SWCNT)-alginate hydrogel composites. Among the parameters of importance in the formation of an alginate-based hydrogel composite with single-walled carbon nanotubes, are their varying degrees of purity, their particulate agglomeration and their dose-dependent correlation to cell viability, all of which have an impact on the resultant compositeâ??s efficiency and effectiveness towards biomedical applications. To promote their homogenous dispersion by preventing agglomeration of the SWCNT, at first, we used three different surfactants-sodium dodecyl sulfate (SDS-anionic), cetyltrimethylammonium bromide (CTAB-cationic), and Pluronic F108 (nonionic). After experimentation and corroboration through evidence obtained …

Abstraction Techniques In Security Games With Underlying Network Structure, Anjon Basak

Open Access Theses & Dissertations

In a multi-agent system, multiple intelligent agents interact with each other in an environment to achieve their objectives. They can do this because they know which actions are available to them and which actions they prefer to take in a particular situation. The job of game theory is to analyze the interactions of the intelligent agents by different solution techniques and provide analysis such as predicting outcomes or recommending courses of action to specific players. To do so game theory works with a model of real-world scenarios which helps us to make a better decision in our already complex daily …

Assessment Of Hydraulic And Structural Behavior Of Inundated Pavements, Mojtaba Asadi

Open Access Theses & Dissertations

Severe flooding events have increasingly inundated the transportation infrastructure, including road networks, across the world and the Unites States. Such extreme events induce significant ingress of water into the pavement layers, which in turn leads to structural defects due to the reduction of the shear strength and resilient moduli of the soil layers, asphalt stripping in flexible pavements, pumping effect in rigid pavements, migration of fines into drainable layers, and swelling of expansive soils. Consequently, premature pavement failure may take place that can impose unforeseen maintenance/rehabilitation costs to highway agencies. Although some experimental research studies have been conducted to assess …

Understanding The Digital Lives Of Transnational Students: A Case Study, Chowaing Chagra Belekeh

Open Access Theses & Dissertations

The proliferation and the fast-paced evolution of digital information communication technologies (ICTs) in contemporary times have arguably raised concern for us to comprehend what we do with these technologies and what these technologies do for us. The experience of engaging these technologies may not necessarily be the same for everyone—especially students who come from around the world to attain post-graduate degrees in the United States. This research focused on understanding the digital lives, choices, and experiences of transnational students who navigate and negotiate geopolitical borders and boundaries (physical)– in their quest for education. Using a case study analysis and collecting …

Adiposity And Arterial Stiffness: Associations With Prefrontal Cortex Hemodynamic Response And Response Inhibition, John William Capps

Open Access Theses & Dissertations

Obesity is a global health crisis associated with increased arterial stiffness, diminished brain reactivity, and diminished executive functioning. Inhibitory control, a specific domain of executive functioning, is known to be especially important to behaviors influencing health. The current study aimed to determine if increased adiposity and arterial stiffness were associated with performance and brain activation for two inhibitory control subtypes, response restraint, and response cancellation. Carotid-femoral pulse wave velocity, the Cued Go/No-go Task, the Stop Signal Task, and functional Near-Infrared Spectroscopy (fNIRS) were used to investigate these relationships. Pearson correlations indicated that slower stop-signal reaction time was associated with a …

Low Weight Design Of A Pressure-Fed System For A Small Payload Launch Vehicle, Lucero Buendia

Open Access Theses & Dissertations

Carbon fiber reinforced polymer (CFRP) composites have become of great interests to aerospace industries because of their low-cost, lightweight and their tailorable mechanical properties. In aerospace structures, for example, heavy metals have been used in cryogenic fuel and oxidizer tanks for over 50 years. However, weight savings can be substantial if materials such as composites are used instead. From Delta IV heavy-lift launch vehicle it is known that cryogenic composite tanks can save approximately up to 30% of weight in fuel and oxidizer tanks. Although there is a wealth of studies in the mechanical behavior of composites at room temperature, …

Formulation Strategies To Enhance Solubility And Permeability Of Small Molecules For Drug Delivery Applications, Pradeep Kumar Bolla

Open Access Theses & Dissertations

All the new chemical entities/drug molecules intended for therapeutic use must be administered using an appropriate delivery system/dosage form to achieve maximum bioavailability. However, designing a drug delivery system is complex as several factors such as lipophilicity, molecular mass, crystallinity, ionic charge, polymorphic forms and hydrogen bonding) affect the solubility and permeability of these molecules. Biopharmaceutics drug classification system (BCS) categorizes the existing drugs into four classes based on the aqueous solubility and membrane permeability and it is reported that >70% of the drugs are poorly soluble and belong to BCS class II and BCS class IV. Several physical, chemical …

Morphological Production Accuracy Patterns In Younger And Older Spanish-English Bilingual Children, Isabel Angelica Cano

Open Access Theses & Dissertations

Clinicians require a model of typical bilingual language development. Morphological production accuracy patterns vary in Spanish-English (S-E) bilingual children considering differences in the exposure and use of their two languages compared to their monolingual peers. The purpose of the current study was to examine morphological production accuracy patterns in thirty younger (3- to 4-years old) and older (5- to 6-years old) S-E bilingual children utilizing English and Spanish Morphosyntax subtests from a bilingual language screener. Across development, older bilingual children were more accurate on all forms in both English and Spanish than younger bilingual children. Across languages, all S-E bilingual …

At The Mercy Of The Mexican Supreme Court: The Implications Of Party Capability On Indigenous People's Cases, Alan Cardenas

Open Access Theses & Dissertations

Indigenous Peoples in Mexico have long struggled in securing their rights in colonizing states. Applying party capability theory, this paper seeks to empirically understand the Mexican Supreme Court's behavior in cases pertaining to Indigenous Peoples. This paper thus evaluates the degree to which the Mexican Supreme Court is indeed an impartial actor that produces "equal protection under the law" for everyone (Galanter, 1974). Specifically, this paper examines the questions: To what extent does the Mexican Supreme Court protect Indigenous Peoples' rights? Are Indigenous Peoples legally affected by the power disparity perpetuated by the inequality in the country? This paper thus …

A Comparative Study Of The Impact Of Depth In Deep Learning Architectures, Kirsten Byers

Open Access Theses & Dissertations

Machine Learning continues to evolve as applications become more complex. Neural Networks, or Deep Networks, are integral to machine learning and the entire taxonomy of Artificial Intelligence [Sze17]. Intelligent structures and algorithms continue to advance, keeping pace with the complexi-ty of data. Changes in architecture, algorithms, and parameters are necessary to keep up with com-putational complexity and data available. This study focuses on how changes in depth of the archi-tecture affect performance on three distinct datasets, including one on Heart Disease. An adaptable network is created in original code, trained, and tested on these datasets. Its performance parameters are observed …

A Mixed Methods Approach To Studying Risk Perceptions Among Latina Patients In The Emergency Department: Gender Roles And Hiv Risk Behaviors, Juliana Cardoso Smith

Open Access Theses & Dissertations

The intersection of race and gender are critical determinants of healthcare experiences. Women from minority groups face unequal access to healthcare, such as HIV testing; consequently, leading to worse outcomes in several health conditions compared to Non-Hispanic White females, including HIV rates. Human Immunodeficiency Virus (HIV) affects an estimated 1.2 million individuals in the United States, disproportionately affecting ethnic minorities. Latinas are estimated to be four times more likely to be diagnosed with HIV compared to white females. Despite the availability of HIV testing in Emergency Departments across the United States, patients may still underreport their HIV risk and have …

Graduate School Application Accessibility For International Students, Estefania Castillo

Open Access Theses & Dissertations

The graduate school application is a time consuming, yet important, process that can often be complicated for students. However, this process is made even more complicated for international students who often face extra steps and other obstacles when applying to graduate programs in the US. Following my own experience of applying to a master's program as an international student, I set out to further explore how international students experienced and navigated this process. This research project explored the graduate school application process through the experiences of international students that were shared in testimonios through platicas, or open and friendly conversations. …

Autonomous Trading Strategies For Dynamic Energy Markets, Moinul Morshed Porag Chowdhury

Open Access Theses & Dissertations

With increasing energy demand and an intermittent supply of renewable energy sources, our current energy grid needs a transformation towards a more robust, reliable energy trading architecture. The smart grid promises this architecture as the future of the present energy market, where traders will use digital technologies to automate the management of power delivery. It will improve many issues of the current energy grid such as sustainable, clean, renewable, reliable and secure energy supply, customer participation in markets, distributed generation, and transparency in energy trading. Using autonomous trading agents, we can bridge several dynamic energy markets and ensure an efficient …

Association Of A Repetitive Manual Task On Inflammatory Biomarker Expression, Heart Rate Variability And Rating Of Perceived Exertion, Daniel Conde

Open Access Theses & Dissertations

The National Institute for Occupational Safety and Health (NIOSH) defines work related musculoskeletal disorders (WMSDs) as a group of disorders involving muscles, tendons, and nerves. The WMSDs symptoms are considered the most common occupational disease, causing limitations in daily activities. Even though there is an association between repetitive manual tasks involving short work cycles, force demanding tasks, and the development of WMSDs, the specific cause of the physiological changes over a long period of time is a cause of debate. The study of mechanisms underlying the physiological changes is essential for the early detection, diagnosis, and appropriate management of WMSDs.

Regulation Of Schlafen 11 Expression, Christian Waldemar Corona Ayala

Open Access Theses & Dissertations

Schlafen 11 (SLFN11) is a member a family of proteins that can be found in mammals. Members of this family are involved in important functions. SLFN11 in particular has been identified as a restriction factor for several evolutionarily disparate viruses such as HIV-1 and Flaviviruses and to play an important role in DNA repair, sensitizing cells to chemotherapy. Despite its relevance SLFN11 remains largely uncharacterized. The aim of this research was to achieve a more comprehensive understanding the regulation mechanism of SLFN 11 expression. Before our research, it was only known that type I interferon (IFN) regulates SLFN11 levels. However, …

Insulin Restores The Neurochemical Effects Of Nicotine In The Mesolimbic Pathway Of Diabetic Rats, Bryan Cruz

Open Access Theses & Dissertations

This study examined whether insulin modulates the neurochemical effects of nicotine in the mesolimbic pathway of diabetic rats. Rats received vehicle or streptozotocin (STZ) to induce hypoinsulinemia. A subset of STZ-treated rats was implanted with insulin pellets that rapidly normalized glucose levels. Two-weeks later, dialysis probes were implanted into the nucleus accumbens (NAc) and ipsilateral ventral tegmental area (VTA). The next day, dialysate samples were collected during baseline and then following systemic administration of nicotine. Samples were also collected following intra-VTA administration of the gamma-aminobutyric acid (GABA)A receptor antagonist, bicuculline. Dopamine, acetylcholine (ACh), GABA, and glutamate levels were assessed using …

Structural Analysis Of Deformed Caprock Associated With A Salt Shoulder At Gypsum Valley Salt Wall, Paradox Basin, Colorado, Hanah Draper

Open Access Theses & Dissertations

This study documents the style and distribution of deformation present in Triassic-age gypsic and carbonate caprock associated with the Gypsum Valley Salt Wall Salt Shoulder in the Paradox Basin, Colorado in order to determine the mechanism and timing of deformation. Mapping of gypsic and carbonate capstone facies shows that the caprock layering that was generated during formation has been deformed by large-and-small-scale folding and faulting, brecciation, and boudinage. Deformation within the caprock resulted in widely variable orientations along the length of the salt shoulder, that also varies locally in intensity of deformation and with proximity to the passively rising diapir …

Sensory Integration And Its Role In Behavioral Plasticity In Children Diagnosed With Autism Spectrum Disorder, Clarissa Diaz

Open Access Theses & Dissertations

Although commonly characterized by communicative and social impairments, Autism Spectrum Disorder (ASD) presents a number of developmental deficits related to movement planning and action. The extent of these deficits to the entire neuromuscular system, as well as the individual input/output loops are still not well understood. Given the dynamic interplay between our plans, actions and outcomes lay the foundation for later mature motor behavior, it is critical to understand the unique motor learning processes these nervous systems face while a higher level of training plasticity may be present. A recent study examined the kinematics (acceleration, velocity, smoothness, etc.) of upper …

Behavioral Ecology Of A Desert Ambush Predator: Assessing Movement Patterns, Habitat And Microhabitat Use, And The Innate Feeding Response Of Eastern Black-Tailed Rattlesnakes (Crotalus Ornatus) In The Northern Chihuahuan Desert, James Emerson

Open Access Theses & Dissertations

Research on the ecology and evolution of rattlesnakes has been sporadic over the past 80 years, but has seen recent expansion into the diverse fields of physiology, physiological ecology, life history, behavioral ecology, ethology, reproductive biology, chemical ecology, venom biochemistry and medicine, conservation, and many other subdisciplines. The development of small, implantable VHF radiotransmitters in the 1980s revolutionized research in the field of behavioral ecology for rattlesnakes, which are uniquely suited for radiotelemetry studies because they possess several morphological, physiological, and behavioral characteristics that are unique among terrestrial vertebrates. The widespread application of radiotelemetry by the mid-1980s advanced the model …

Juvenile Fluoxetine Treatment Mediates An Anxiogenic Phenotype That Is Ameliorated By Its Re-Exposure In Adulthood, Francisco Javier Flores Ramirez

Open Access Theses & Dissertations

Accumulating preclinical evidence indicates that early-life exposure to psychotropic medications induce an anxiogenic-like behavioral profile in later life. However, these preclinical approaches have been conducted primarily using male subjects. This is problematic since clinical data indicates that women are more likely to be diagnosed with anxiety disorders than their male counterparts, and thus, women are prescribed with psychotropic medications like fluoxetine (FLX), a selective serotonin reuptake inhibitor (SSRI), at significantly higher rates. Therefore, the goal of this Dissertation is to examine whether alterations in behavioral responses to anxiety-eliciting stimuli are exhibited in adulthood, as a result of early-life FLX exposure. …

Principals' Perceptions Of Their Preparedness To Lead Inclusive Schools For Students With Disabilities: An Action Research Study Of A Principal Preparation Program On The U.S.-Mexico Border, Ignacio Estorga Iii

Open Access Theses & Dissertations

In the "age of accountability," every student counts. This includes students with disabilities. Principals play a vital role in ensuring that students with disabilities receive a high-quality education. How are university-based preparation programs preparing aspiring administrators to meet the challenges of ensuring a fair and equal education for every student, including students with disabilities? Nearly 25 years ago, a study of principal preparation programs concluded that most principals were ill prepared when they began their leadership tenure. In 2009, a study found that, although there had been an increase in the number of hours that principal preparation programs required for …

We Are All Green: Stereotypes For Female Soldiers And Veterans, Katherine French

Open Access Theses & Dissertations

As the number of females in the U.S. military continues to rise, the need for research concerning this cohort becomes increasingly important. In consideration of gender role theory, society may assume that soldiers and veterans are male, due to stereotypes. Thus, it was hypothesized that participants would be more likely to implicitly associate military (i.e. prior military or combat veteran) as male compared the neutral condition (i.e. prior Peace Corp volunteer). The current study (N = 174) used gender pronouns as implicit measures of gender assumptions. Participants were assigned to read six gender neutral scenarios; three focal scenarios (i.e. combat …

Identification Of A Novel Single Amino Acid Substitution (V666g) Of Jak1 From A Patient With Acute Lymphoblastic Leukemia Impairs Jak3 Mediated Il-2 Signaling, Alice Hernandez Grant

Open Access Theses & Dissertations

The Janus kinase (JAK) family, notably JAK1, JAK2 and JAK3 are recognized as oncogenic drivers in high risk Acute Lymphoblastic Leukemia (ALL). The bulk of activating JAK mutations are thought to occur within functional hot-spots across Janus Homology (JH) domains. The most frequently mutated regions is the JH2 pseudo-kinase, which provides a negative regulatory role to the adjacent catalytically active JH1 kinase domain. Despite the prevalence of JAK activating mutations and a need for new therapeutic inhibitors, there is a lack of understanding in the allosteric regulation of JAK kinases. Here we sought to identify mutations involved in driving ALL …

Trials Of Belonging: Indigenous Peoples' Struggle With Law And Power In Twentieth-Century North America, Kevin Thomas Guay

Open Access Theses & Dissertations

Spanning multiple fields of scholarly inquiry, the bulk of this study concerns itself with competing notions of sovereignty, citizenship, boundary-making, and belonging in twentieth and twenty-first century Indigenous North America. Situated at the productive confluence of Borderlands history, Native American and Indigenous Studies, Critical Legal Studies, and Immigration history, this Dissertation analyzes the numerous treaties, codes, edicts, bylaws and other expressions of settler colonial jurisprudence that penetrated the everyday lives of Indigenous peoples across North America. These statutes-designed to limit Native power, dissolve Indigenous cultural identity, and strip tribal peoples of their landholdings and personhood-constituted an ongoing settler colonial project …

Region-Specific Modifications Of Synaptic Proteins In Response To Early-Life Adversity In The Rat Brain, Jameel Nasser Hamdan

Open Access Theses & Dissertations

Drug addiction is a serious condition affecting approximately 19.7 million people in the United States alone (SAMHSA 2018). Exposure to stress and other adverse conditions has been shown to impact drug-taking behavior and making individuals more vulnerable to addiction. In those already suffering from addiction, abstaining from drug use often gives way to relapse after a stressful event (Lu, Shepard et al. 2003; Shaham, Erb et al. 2000). The experience of adversity during early-life can cause long-lasting changes in the brain, affecting development, behavior, learning and memory, and critical thinking processes, which may persist into adulthood (Aisa, Tordera et al. …