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Selective Interactions Of O-Methylated Flavonoid Natural Products With Human Monoamine Oxidase-A And -B, Narayan D. Chaurasiya, Jacob Midiwo, Pankaj Pandey, Regina N. Bwire, Robert J. Doerksen, Ilias Muhammad, Babu L. Tekwani

Faculty and Student Publications

A set of structurally related O-methylated flavonoid natural products isolated from Senecio roseiflorus (1), Polygonum senegalense (2 and 3), Bhaphia macrocalyx (4), Gardenia ternifolia (5), and Psiadia punctulata (6) plant species were characterized for their interaction with human monoamine oxidases (MAO-A and -B) in vitro. Compounds 1, 2, and 5 showed selective inhibition of MAO-A, while 4 and 6 showed selective inhibition of MAO-B. Compound 3 showed ~2-fold selectivity towards inhibition of MAO-A. Binding of compounds 1-3 and 5 with MAO-A, and compounds 3 and 6 with MAO-B was reversible and not time-independent. The analysis of enzyme-inhibition kinetics suggested a …

The Blood Money Of The Human Body Parts In Islamic Jurisprudence, Jamal Zaid Kielani, Adnan Thahir

An-Najah University Journal for Research - B (Humanities)

In This research, entitled (The blood money of the Benefits of the human body partsin Islamic jurisprudence) we talked about the concept of the blood money (Dyia). We have also talked about related terms and the meaning of blood money, which is the financial the victim or heirs of a victim in the cases of murder, bodily harm or property damage. The research also discussed the principles in which the blood money is required and the amount of duty for each sex according to the type and condition of the killing.We concluded the research by showing the amount of blood …

Ethoxylation And Polymerization Of Cardanol Derived Bifunctional Monomers, James Mgaya

Journal of Humanities and Social Sciences

Cardanol and its derivative; 3-(non-8-enyl)phenol (obtained by ethenolysis reaction of cardanol) were ethoxylated via one-pot reaction with urea and ethylene glycol using Na2CO3/ZnO as co-catalysts. The ethoxylates were later methoxycarbonylated using a 1,2-bis(ditertbutylphosphinomethyl)benzene (DTBPMB) modified palladium catalyst to produce ethoxylated bifunctional monomers. Polymerization of these monomers by heating in the presence of a standard polymerization catalyst, Ti(OBu)4, formed oligomers that were plastic-like. Analysis of these oligomers by MALDI-TOF MS indicated the condensation of up to nine monomer units.

The Rural-Urban Divide In Tanzania: Residential Context And Socioeconomic Inequalities In Maternal Health Care Utilization, Neema Langa, Tirth Bhatta

Sociology Faculty Research

Background Existing studies in Tanzania, based mostly on rural samples, have primarily focused on individual behaviors responsible for the lower utilization of maternal health care. Relatively less attention had been paid to inequalities in structural circumstances that contribute to reduced utilization of maternal health care. More importantly, scholarship concerning the impact of the rural-urban divide on socioeconomic disparities in the utilization of maternal health care is virtually nonexistent in Tanzania. Methods Drawing from the Demographic Health Survey (2015-2016) conducted in Tanzania, our study includes a total of 3,595 women aged between 15-49 years old, who had given birth in five …

Finding Aid For The Sterling Plumpp Collection (Mum00368)

Archives & Special Collections: Finding Aids (alphabetical)

Collection contains typed and handwritten manuscripts, poems, notebooks, prose and reviews, galleys, correspondence, journals and magazines, and several cataloged books related to the life and work of Sterling Plumpp. Items were created 1962-1986.

Genetics And Geography Of Leukocyte Telomere Length In Sub-Saharan Africans, Steven C Hunt, Michael A Province, Et Al.

2020-Current year OA Pubs

Leukocyte telomere length (LTL) might be causal in cardiovascular disease and major cancers. To elucidate the roles of genetics and geography in LTL variability across humans, we compared LTL measured in 1295 sub-Saharan Africans (SSAs) with 559 African-Americans (AAms) and 2464 European-Americans (EAms). LTL differed significantly across SSAs (P = 0.003), with the San from Botswana (with the oldest genomic ancestry) having the longest LTL and populations from Ethiopia having the shortest LTL. SSAs had significantly longer LTL than AAms [P = 6.5(e-16)] whose LTL was significantly longer than EAms [P = 2.5(e-7)]. Genetic variation in SSAs explained 52% of …

Covid-19 Information Seeking Strategies Of Rural Dwellers In Delta North, Nigeria, Rhima Tracy Efe

Library Philosophy and Practice (e-journal)

The study assessed the COVID-19 information seeking strategies of rural dwellers in Delta North, Nigeria. This study adopted a survey research design. Fifty (50) respondents were randomly selected from each of the rural communities in Delta North used for the study, which amounted to 450 respondents used for the study. Out of the 450 copies of the questionnaire distributed to the respondents, the researcher was able to retrieve 418 copies of the questionnaire from the rural dwellers, thus there was 92% response rate. The method of data analysis adopted was descriptive statistics covering frequency count and percentage. The finding of …

Validation Of Kiswahili Version Of Hoqolhivbref Questionnaire Among People Living With Hiv/Aids In Tanzania: A Cross-Sectional Study, Nuru Kondo, Tumbwene Mwansisya, Eric Aghan, Riaz Ratansi

Faculty of Health Sciences, East Africa

Background: Quality of life is an important element of surveillance in people living with HIV/AIDS. WHO has developed an HIV specific quality of life tool (WHOQOLHIV-Bref) for assessing Quality of life of HIV individuals. This tool takes into account the different cultural variations that exist worldwide and hence enable assessment of the quality of life across different cultures. Despite its preliminary sound validity and reliability from several studies, the developers recommend it to be validated in different cultures to fully assess its psychometric properties before its adaptation.

Objectives: To evaluate the validity and reliability of WHOQOLHIV-Bref questionnaire in …

State Transition Modeling Of Complex Monitored Health Data, Jörn Schulz, Jan Terje Kvaløy, Kjersti Engan, Trygve Eftestol, Samwel Jatosh, Hussein Kidanto, Hege Ersdal

Faculty of Health Sciences, East Africa

This article considers the analysis of complex monitored health data, where often one or several signals are reflecting the current health status that can be represented by a finite number of states, in addition to a set of covariates. In particular, we consider a novel application of a non-parametric state intensity regression method in order to study time-dependent effects of covariates on the state transition intensities. The method can handle baseline, time varying as well as dynamic covariates. Because of the non-parametric nature, the method can handle different data types and challenges under minimal assumptions. If the signal that is …

The Influence Of Economic Factors And Policies On Deforestation In Tanzania, Thadei D. Sagamiko, Nyimvua Shaban Mbare

Journal of Humanities and Social Sciences

In this paper we analysed the influence of economic factors and policy on the rate of deforestation in Tanzania. A multiple linear regression model was formulated and the effects of each factor on deforestation were tested. The ordinary least squares method was used to estimate the model parameters. Correlation analysis revealed that per capita income, per capita purchasing power, and electricity consumption have positive relationship with deforestation rate; while inflation rate and poverty rate have a negative relationship with deforestation rate. All factors were found to be significant and were used for regression analysis. By considering the p-value at 5% …

Overview Of Antiretropulsion Devices For Prevention Of Inadvertent Stone Migration During Pneumatic Lithotripsy For Ureteric Stone, Ali Akbar Zehri, Miten Patel, Philip Adebayo, Authar Ali

General Surgery, East Africa

The purpose of the present chapter is to provide an update about the use of preventive devices used to stop retrograde stone migration during pneumatic lithotripsy for ureteric stone management. The aim to reduce the cost, ancillary procedure, reduce the operative time and improve the stone free rate. The hunt for ideal cadget to stop retrograde stone migration is still continue in 21 century.

Tanzanian Rule While Zanzibar Plays The Fool? The Invalidity Of Zanzibari Unease Over Tanzanian Mainland Dominance, 1964–1991, Bhadrajee S. Hewage

Armstrong Undergraduate Journal of History

On April 26, 1964, the People’s Republic of Zanzibar merged with the Republic of Tanganyika to form the Tanzanian Union. Yet the circumstances surrounding the formation of this Union and the nature of the Union itself raise several unanswered questions. Indeed, some Zanzibaris fear that their island archipelago has been effectively “taken over” by Tanganyika through the guise of the Union government of the Tanzanian mainland. This manuscript explains how Zanzibari fears over the archipelago’s usurpation have no basis since the current and evolving nature of Zanzibar’s autonomy and legal rights have enabled the islands to become a strong player …

Comparison Of Centrifugation And Solid Phase Extraction (Spe) Methods Of Sample Preparations In Determination Of Residues Of Drugs Of Abuse In Urine, John Mahugija, Anastazia Wandwi, Kessy Kilulya

Tanzania Journal of Science

Detection of drugs of abuse in urine samples depends on their composition, absorption, distribution, physical and chemical properties, concentrations, elimination properties, and the techniques employed. This study compared the performance of centrifugation and solid phase extraction (SPE) methods in the determination of levels of drugs of abuse and their metabolites in urine samples collected from drug abusers. Analysis was performed using liquid chromatography-tandem mass spectrometry (LC-MS-MS). Calibration was done using both internal and external standards. The recovery values were generally greater in centrifugation method than in SPE method, but the recoveries in both methods were within an acceptable range. Linearity …

Antibacterial And Anti-Hiv-1 Reverse Transcriptase Activities Of Selected Medicinal Plants And Their Synthesized Zinc Oxide Nanoparticles, Rose J. Masalu, Sai Ngassa, Grace A. Kinunda, Cyprian B. Mpinda

Tanzania Journal of Science

Human Immunodeficiency Virus infection and Acquired Immune Deficiency Syndrome (HIV/AIDS) and associated opportunistic infections are still global health concerns. Traditional medicines have been used for managing these infections, with little about their biological activities being known. This study evaluated antimicrobial and anti-HIV-1 Reverse Transcriptase (RT) activities of medicinal plants; Harungana madagascariensis, Sapium ellipticum, Pseudospondias microcarpa, Capparis erythrocarpos, and Plectranthus barbatus; and activities of zinc oxide nanoparticles synthesized from aqueous extracts of H.  madagascariensis. Results revealed that aqueous and ethyl acetate extracts of H. madagascariensis, S. ellipticum, P. microcarpa; and ethyl acetate extracts from P. barbatus exhibited minimum inhibitory concentrations ranging …

Detection Of Extended Spectrum Beta-Lactamase Producing Escherichia Coli From Urinary Tract Infection In General Hospital, Minna, Nasiru U. Adabara, Naimat D. Bakinde, Sherifat O. Enejiyon, Tijani Salami, Doosuur Iorzua

Tanzania Journal of Science

Possession of virulence factors such as extended spectrum beta lactamase (ESBL) by pathogens generally exacerbates morbidity as well as increases healthcare costs. This study determined the production of ESBL among Escherichia coli isolated from the urinary tracts of subjects attending General Hospital, Minna, Nigeria. One hundred and fifty (150) urine samples were collected from subjects and cultured on CLED agar for the isolation of E. coli. Antibiotic susceptibility testing was done using Kirby Bauer disk diffusion method, while the phenotypic identification of ESBL-producing strains was carried out using double disk synergy test. All results were interpreted based on Clinical and …

Improved Image Quality In Digital Mammography Using Anti-Scatter Grids, Samson O. Omondi, Peter K. Msaki, Ramadhan R. Kazema, Innocent J. Lugendo

Tanzania Journal of Science

Curability and effective management of breast cancer are dependent on its early detection. Early diagnosis strategies focus on providing timely access to breast cancer treatments by reducing barriers and improving access to effective early diagnosis. Mammography is the screening method of choice but suffers from degrading effects of scatter photons obstructing visualization of ductal carcinoma in situ and micro-calcifications in the breast. Quantitative evaluation of scatter suppression by anti-scatter grid using the beam stopper method has been investigated. Breast tissue equivalent phantom, polymethyl methacrylate was evaluated at X-ray mammographic nominal energy ranges. The anti-scatter grid used had aluminium interspace material …

Synthesis And Ftir Characterization Of Mg-Hydroxylapatite Derived From Dolostone With High Dolomite Mineral Content, Wilson L. Mahene, Charles Gervas, Askwar H. Hilonga, Revocatus L. Machunda

Tanzania Journal of Science

We present the synthesis of magnesium-substituted hydroxylapatite starting from locally available dolostone. The apatite was prepared by a reaction between heat pre-treated dolostone powder with phosphoric acid, maintained at the pH of 12.5 using sodium hydroxide. The resultant material was then calcined at 500 °C, 600 °C, 700 °C, 800 °C and 900 °C. The precursor dolostone was characterized by organic elemental analyser (CHNS-O analyser), X-ray fluorescence (XRF) and Fourier transform infrared spectroscopy (FTIR), while the synthesized material was characterized by using FTIR. Results indicated that the dominant mineral in the carbonate rock materials was near-stoichiometric dolomite, while the synthesized …

Microbiological, Physicochemical And Heavy Metals Assessments Of Soils And Selected Vegetables Grown On Rumde-Doubeli Irrigated Farmland In Yola Nigeria, Mohammed Inuwa Ja’Afaru, Joel Uyi Ewansiha, Abdulwahab Dahiru, Konjerimam Ishaku Chimbekujwo

Tanzania Journal of Science

Leaf parts of vegetable plants grown on irrigated farmlands and are easily accessed by contaminants; pose greater risks of being contaminated with heavy metals. Soil, irrigation water and edible vegetable plants were collected and evaluated for concentrations of heavy metals using Atomic Absorption Spectrophotometry (AAS) and standard laboratory methods. Physicochemical parameters of irrigation water, compared with WHO limits for chloride (326.14 + 7.03 mg/L, 250 mg/L), total hardness (196.0 + 8.72 mg/L, 150 mg/L), chemical oxygen demand (286.4 ±1.35 mg/L; 150 mg/L) and alkalinity (171.0 + 4.36 mg/L, 120 mg/L) were significantly (p ˂ 0.05) higher than the control sites …

Socio-Demographic Evaluation Of Ownership Levels And Utilization Rates Of Llins Against Malaria Vectors Within Urban Settlements Of Osogbo District, Osun State, Nigeria, Kamilu A. Fasasi, Akinlabi M. Rufai, Damilola H. Familoni, Monsuru A. Adeleke

Tanzania Journal of Science

Globally, malaria is one of the major endemic diseases of public health importance caused by Plasmodium spp. and transmitted by Anopheles mosquitoes. Efforts to eradicate malaria disease are on the decline despite appreciable progress recorded in the past. This warranted holistic review of malaria interventions which include among others, the assessment of Long Lasting Insecticidal Treated Nets (LLINs). Adopted questionnaires from Roll Back Malaria (RBM), World Health Organization (WHO) and United Nations Children’s Fund (UNICEF) were administered to evaluate ownership levels and utilization rates of LLINs against malaria vectors in urban settlements of Osogbo district, Osun state, Nigeria. Out of …

Anti-Diarrhoeal Effects Of Aqueous Extract Of Vitex Doniana Stem Bark In Castor Oil-Induced Wistar Rats, Aliyu O. Amuzat, Yakubu Ndatsu, Mohammed J. Adisa, Rukayyah S. Sulaiman, Hadiza Mohammed, Abubakar A. Yusuf, Hauwa M. Ndayako

Tanzania Journal of Science

Vitex doniana is a medicinal plant commonly used in traditional medicine for the treatment of diarrhoea-related disorders.  In the present study, aqueous extract of Vitex doniana stem bark was evaluated for anti-diarrhoeal effects. Thirty albino rats of average weight 124 ± 4.35 g were distributed into five groups. Groups 1, 2, 3, 4 and 5 were orally administered 2 mL of normal saline, 2.5 mg/kg bodyweight (bw) loperamide, 100, 200, 400 mg/kg bodyweight of aqueous extract of V. doniana stem bark, respectively. The extract was evaluated using feacal characteristics, gastrointestinal motility and enteropooling test. Results for phytochemical screening revealed the …

Geological And Geochemical Characterisation Of Pegmatites Around Olode, Southwestern Nigeria, Razak O. Jimoh, Akinade S. Olatunji

Tanzania Journal of Science

Olode is prolific in terms of pegmatites, occurring in different ways as large intrusive bodies, as veins and dykes, discordantly intruding the host rocks of mica schist, gneiss and granite. This study is aimed at the geological and geochemical characterisation of pegmatites around Olode. Field investigation was undertaken to determine the occurrences and relationships of the pegmatites with the host rocks. Fresh pegmatite samples were studied petrographically and geochemically. Two main lithologically and chronologically different groups of pegmatites were distinguishable in the study area. These were the tourmaline pegmatites associated with the Older Granite rocks and the NE-SW trending beryl-bearing …

Annual Committed Effective Doses Of Primordial Radionuclides And Excess Lifetime Cancer Risk To The Consumers Of Some Foodstuffs In Lagos, Southwest Of Nigeria, Olusegun Sowole, Sadudeen Kayode Aliyu

Tanzania Journal of Science

Food plays vital role in the survival of man as it provides necessary nutrients to the body in order to carry out the daily activities and also to be in good health. Activity concentrations of 40K, 238Uand 232Th in some foodstuffs from three highly rated markets   in Lagos, Southwest of Nigeria have been determined by gamma spectrometry method using NaI (TI) detector coupled with a pre-amplifier base to a multiple channel analyzer (MCA). Fifteen (15) samples of maize flour, yam flour, beans, cassava flour and rice were randomly purchased from the markets: Ketu, Oyingbo and Ikeja. The highest activity concentrations …

Trypsin Immobilization On Thiol Functionalized Mesoporous Silicas Prepared Using Castor Oil Template, James E. Mgaya

Tanzania Journal of Science

Mesoporous thiol modified silicas have been prepared using castor oil as a templating agent. The preparation was done through a co-condensation of 3-mercaptopropyltriethoxysilane and tetraethylorthosilicate in a 1:4 molar ratio. Physisorption studies showed that the prepared mesoporous silicas have an average pore diameter of 9 nm, pore volume of 1.0336 cm3/g and surface areas of up to 605 m2/g. FTIR confirmed the attachment of thiol groups on the surface of the prepared mesoporous silica as evidenced with an absorption band at around 2600 cm–1. SEM images indicated agglomeration of the prepared particles. The prepared thiol modified silicas were successfully immobilized …

Cashew Plant-Mediated Biosynthesis Of Silver Nanoparticles And Evaluation Of Their Applications As Antimicrobial Additive For Consumer Care Products, Isiaka A. Adelere, David O. Aboyeji, Felicia O. Akindurodoye, Nasiru U. Adabara, Hausatu Babayi

Tanzania Journal of Science

This study reports the biogenic synthesis of silver nanoparticles (AgNPs) using aqueous extract obtained from Anacardium occidentale stem bark and evaluation of their antibacterial activities as well as their potential applications as antimicrobial additives for detergent and toothpaste. The biosynthesized AgNPs were analyzed using UV–Vis spectroscopy, Fourier-transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The particles were dark brown in colour with maximum absorbance at wavelength 419 nm. They were mainly spherical in shape with size ranges from 20 to 60 nm. The peaks of FTIR spectrum revealed that their formation was facilitated by protein molecules present in the …

Levels And Exposure Risks Of Lead, Arsenic And Mercury From Selected Lipstick And Nail Polish Cosmetics Marketed In Dar Es Salaam, Tanzania, Gerald S. Kulwa, Matobola J Mihale

Tanzania Journal of Science

Presence of Pb, As and Hg in selected lipstick and nail polish cosmetics sold at different shopping malls and retail outlets in Dar es Salaam was determined by microwave plasma  atomic emission spectrometry due to their public health effects. Pb was detected in 100% (n = 25) of lipsticks and 53.3% (n = 15) of nail polishes. Arsenic was detected in 36% of lipsticks and 86.7% of nail polishes, and Hg was detected in 44% of lipsticks and 80% of nail polishes. All metal levels in both cosmetics were below the World Health Organisation (WHO) and Tanzania Bureau of Standards …

Corn Stover As Substrate For Biogas Generation And Precursor For Biosilica Production Via Anaerobic Digestion, Akinola D. Olugbemide, Lajide Labunmi, Ikhazuagbe H Ifijen, Damilare I. Ogungbemide

Tanzania Journal of Science

Production of fuels and chemicals from renewable biomass is crucial to sustainability of bio-based economy. In this study, anaerobic digestion of corn stover (CS) was carried out to produce biogas under mesophilic conditions. The study also investigated the potential of corn stover digestate ash as a potential source for biosilica production. A cumulative volume of 930 mL of biogas was produced with methane content of 85.87%. Higher and lower calorific values of biogas were calculated to be 36.30 MJ/m3 and 32.70 MJ/m3, respectively. Calcination of raw CS (RCS) and the digestate (CSD) was carried out at 600 °C for 3 …

Total And Available Fluoride Content In Toothpastes Sold In Dar Es Salaam, Tanzania, Monica Mbaraka Ndoile

Tanzania Journal of Science

A total of eleven (11) different toothpaste brands (imported and manufactured in Tanzania) sold in Dar es Salaam were evaluated for Total Fluoride (TF) and Total Soluble Fluoride (TSF) concentrations. To protect the subject’s identity, the samples were coded. Four selected toothpastes were analyzed for potentially bioavailable fluoride by examining the relationship between TSF in tooth brushing residues and in that of the toothpaste. The results indicated that measured TF of the toothpaste samples coded as TPSA, TPSC and TPSH were consistent to the one declared by the manufacturers. On the other hand, samples coded as TPSB, TPSD, TPSE, TPSF, …

Coal Exploration Using Electrical Resistivity Method In Some Parts Of Benue Trough, Nigeria, Saminu Olatunji, Abdulgafar T. Jimoh

Tanzania Journal of Science

Geoelectrical resistivity sounding technique was used to delineate the occurrence and extents of coal seam. Fifteen points were sounded with Schlumberger configuration in the suspected coal deposit site bounded by longitudes 7.344° E and 7.366° E, and latitudes 7.318° N and 7.33° N. The vertical electrical sounding (VES) data were analyzed and the corresponding geo-electric parameters at various depths were modeled. The earth model within the study area was correlated with available lithology of a nearby mine site. The sounding signatures are KQHK and KHK curve types which revealed five to six distinct geo-electrical equivalent layers. The wet to dry …

Performance Evaluation Of Aspect Dependent-Based Ghost Suppression Methods For Through-The-Wall Radar Imaging, Mugundu Rambika, Abdi T. Abdalla, Baraka J. Maiseli, Alfred J. Mwambela

Tanzania Journal of Science

There are many approaches which address multipath ghost challenges in Through-the-Wall Radar Imaging (TWRI) under Compressive Sensing (CS) framework. One of the approaches, which exploits ghosts’ locations in the images, termed as Aspect Dependent (AD), does not require prior knowledge of the reflecting geometry making it superior over multipath exploitation based approaches. However, which method is superior within the AD based category is still unknown. Therefore, their performance comparison becomes inevitable, and hence this paper presents their performance evaluation in view of target reconstruction. At first, the methods were grouped based on how the subarrays were applied: multiple subarray, hybrid …

Radiation Dose To The Contralateral Breast And Effectiveness Of Superflab In Dose Reduction During Treatment Of Breast Cancer By Cobalt-60 External Beam, Julius S. Chiuyo, Peter K. Msaki, Ismail N. Makundi

Tanzania Journal of Science

Radiation therapy for breast cancer inevitably results in scattered dose to contralateral breast. Breast tissues being highly sensitive to ionizing radiations, the chance of the contralateral breast developing second cancer after radiation therapy is high. This study investigated dose to contralateral breast and its reduction by superflab during the course of breast cancer radiation therapy. A thorax breast phantom constructed from tissue-equivalent materials and diodes (type IVD2 1137) were used to measure surface doses to the contralateral breast. The mean doses received by the contralateral breast were 2.2% and 7.1% of the prescribed dose of 200 cGy for 5 × …