Digital Commons Network^™

Decline In Land Condition In Astrebla Grassland During Prolonged Drought In Australia, David G. Phelps, David M. Orr, I. W. Houston, L. Rolfe, J. Silcock

IGC Proceedings (1977-2023)

No abstract provided.

Resilience Of Ecosystem Structure And Function During Succession Following Prescribed Burning In A Shrub‐Steppe Ecosystem In Wyoming, Usa, E. Pendall, M. B. Cleary, B. E. Ewers, K. Naithani, H. Kwon

IGC Proceedings (1977-2023)

No abstract provided.

A Rapid Assessment Technique To Evaluate Rangeland Health, Michael Pellant, Jeffrey E. Herrick, P. L. Shaver, F. Busby, D. A. Pyke

IGC Proceedings (1977-2023)

No abstract provided.

Plant Species Diversity As An Indicator Of Sustainable Use Of Astrebla Grasslands In Australia, David M. Orr, David G. Phelps

IGC Proceedings (1977-2023)

No abstract provided.

Current Status And Development Prospects Of Environmental Regulatory System (Historical And Legal Analysis), Nariman Rajabov

Review of law sciences

In this article analyzes the issues of further improving ecological standardization system, with special attention paid to the important question of how the procedure for establishing environmental standards. This issue is discussed in the historical and legal, theoretical and scientific aspect, and justifies the author's suggestions.

Finding Home: Belonging During A Pandemic, Mark Burstein

Presidential Addresses

Lawrence University President Mark Burstein officially opens the university’s 172nd academic year, along with its 2020-21 convocation series, with his virtual matriculation address, “Finding Home: Belonging During a Pandemic.”

Now in his eighth year as Lawrence’s 16th president, Burstein has focused on creating learning communities in which all members can reach their full potential.

A Naturalistic Ethic Supporting A Vegan Diet, Michael Morris

Between the Species

Nutritional evidence suggests that a vegan diet is the most adaptive one for humans. An ethical principle based on following our biological nature (naturalistic ethic) could therefore provide additional support for a vegan diet. However, some argue that humans in the natural world could not eat a vegan diet, since it relies on supplements, particularly vitamin B12. This leads to the conclusion that humans are naturally omnivores, and therefore our natural diet should include small amounts of animal products.

Three approaches to this conclusion are discussed. The first rejects a naturalistic ethic in favour of normative principles based on animal …

General Psychology For Honors Students, Kate Votaw

Open Educational Resources Collection

What are the most effective methods to study for a test? What are the meanings of dreams? How do illusions work? With whom are you most likely to fall in love? These are just a few of the questions that have been asked by psychologists since the birth of the field as an area of scientific research in the 1870’s. This text surveys the basic concepts, theories, and pivotal findings over the past 100 years in the science of Psychology, with special emphasis on contemporary concepts and findings focused on the relation of the brain to normal and pathological behaviors. …

Inhibition Of Mitochondrial Oxidative Metabolism Attenuates Emcv Replication And Protects B-Cells From Virally Mediated Lysis, Joshua D. Stafford, Zachary R. Shaheen, Chay Teng Yeo, John A. Corbett

Biological Sciences Faculty Research & Creative Works

Viral infection is one environmental factor that may contribute to the initiation of pancreatic b-cell destruction during the development of autoimmune diabetes. Picornaviruses, such as encephalomyocarditis virus (EMCV), induce a pro-inflammatory response in islets leading to local production of cytokines, such as IL-1, by resident islet leukocytes. Furthermore, IL-1 is known to stimulate b-cell expression of iNOS and production of the free radical nitric oxide. The purpose of this study was to determine whether nitric oxide contributes to the b-cell response to viral infection. We show that nitric oxide protects b-cells against virally mediated lysis by limiting EMCV replication. This …

The Indiana Statesman, September 24, 2020, Indiana State University

Student Newspaper

Celebrating intellectual freedom; COVID-19 surge caused by Labor Day; Officer indicted in Breonna Taylor case; Schumer seeks to block court replacement before Election Day

Core Neuropsychological Measures For Obesity And Diabetes Trials: Initial Report, Kimberlee D'Ardenne, Cary R. Savage, Dana Small, Uku Vainik, Luke E. Stoeckel

Center for Brain, Biology, and Behavior: Faculty Publications

Obesity and diabetes are known to be related to cognitive abilities. The Core Neuropsychological Measures for Obesity and Diabetes Trials Project aimed to identify the key cognitive and perceptual domains in which performance can influence treatment outcomes, including predicting, mediating, and moderating treatment outcome and to generate neuropsychological batteries comprised of well-validated, easy-to-administer tests that best measure these key domains. The ultimate goal is to facilitate inclusion of neuropsychological measures in clinical studies and trials so that we can gather more information on potential mediators of obesity and diabetes treatment outcomes. We will present the rationale for the project and …

Acer 2018-2019 Annual Report, Australian Council For Educational Research (Acer)

ACER Annual Reports

No abstract provided.

Indigenous Environmental Network And North Coast Rivers Alliance V. President Donald J. Trump, Et Al. And Tc Energy Corporation, Et Al., Kirsten D. Gerbatsch Ms.

Public Land & Resources Law Review

A single cross-border pipeline project has been the epicenter of environmental litigation for the last decade—and it is not over yet. For years, TransCanada Keystone Pipeline, LP and TC Energy have sought to construct and maintain a segment of the Keystone pipeline between the United States and Canada to connect existing pipeline infrastructure and transport crude oil. To do so, the company must first apply and be approved for a permit. Between 2008 and 2012, President Obama twice denied TransCanada Keystone Pipeline and TC Energy’s applications. Then, in 2017 and again in 2019, President Trump unilaterally invited TC Energy’s application …

Neutrophil: A New Player In Metastatic Cancers, Mengyue Wu, Mutian Ma, Zhenya Tan, Hong Zheng, Xia Liu

Toxicology and Cancer Biology Faculty Publications

The interaction between cancer cells and immune cells is important for the cancer development. However, much attention has been given to T cells and macrophages. Being the most abundant leukocytes in the blood, the functions of neutrophils in cancer have been underdetermined. They have long been considered an “audience” in the development of cancer. However, emerging evidence indicate that neutrophils are a heterogeneous population with plasticity, and subpopulation of neutrophils (such as low density neutrophils, polymorphonuclear-myeloid-derived suppressor cells) are actively involved in cancer growth and metastasis. Here, we review the current understanding of the role of neutrophils in cancer development, …

Raman-Guided Subcellular Pharmaco-Metabolomics For Metastatic Melanoma Cells., Jiajun Du, Yapeng Su, Chenxi Qian, Dan Yuan, Kun Miao, Dongkwan Lee, Alphonsus H C Ng, Reto S Wijker, Antoni Ribas, Raphael D Levine, James R Heath, Lu Wei

Articles, Abstracts, and Reports

Non-invasively probing metabolites within single live cells is highly desired but challenging. Here we utilize Raman spectro-microscopy for spatial mapping of metabolites within single cells, with the specific goal of identifying druggable metabolic susceptibilities from a series of patient-derived melanoma cell lines. Each cell line represents a different characteristic level of cancer cell de-differentiation. First, with Raman spectroscopy, followed by stimulated Raman scattering (SRS) microscopy and transcriptomics analysis, we identify the fatty acid synthesis pathway as a druggable susceptibility for differentiated melanocytic cells. We then utilize hyperspectral-SRS imaging of intracellular lipid droplets to identify a previously unknown susceptibility of lipid …

Research Boost, Robbin Ray

UNH Today Archive

No abstract provided.

Improvement Of Drinking Water Properties Using A Novel Biosorbent Material., Mohamed Hussen, Mohamed Gar Alalam, Hisham El-Etriby

Mansoura Engineering Journal

In the present study, a new material has been discovered in the world of natural coagulants and adsorbents to improve drinking water properties. Flaxseed husk was used as a natural coagulant and adsorbent to remove turbidity, natural organic matter and iron from underground water for several wells in Al-Jouf region in the north of the Kingdom of Saudi Arabia. To remove turbidity and natural organic matter, modified flaxseed husk (MFH) was prepared by addition of aluminum sulfate (AS) to flaxseed husk (FH) after removing mucilage and oil. The characterization of FH shows high specific surface area (125.18 m2/g) with average …

When Pandemic Hits: Exercise Frequency And Subjective Well-Being During Covid-19 Pandemic, Ralf Brand, Sinika Timme, Sanaz Nosrat

Publications and Research

The governmental lockdowns related to the COVID-19 pandemic have forced people to change their behavior in many ways including changes in exercise. We used the brief window of global lockdown in the months of March/April/May 2020 as an opportunity to investigate the effects of externally imposed restrictions on exercise-related routines and related changes in subjective well-being. Statistical analyses are based on data from 13,696 respondents in 18 countries using a cross-sectional online survey. A mixed effects modeling approach was used to analyze data. We tested whether exercise frequency before and during the pandemic would influence mood during the pandemic. Additionally, …

Unh Receives $1.8 Million For Biomolecular Research In Diabetes And Cancer, Robbin Ray

Media Relations

No abstract provided.

Mesencephalic Astrocyte-Derived Neurotrophic Factor (Manf) Regulates Neurite Outgrowth Through The Activation Of Akt/Mtor And Erk/Mtor Signaling Pathways, Wen Wen, Yongchao Wang, Hui Li, Hong Xu, Mei Xu, Jacqueline A. Frank, Murong Ma, Jia Luo

Pharmacology and Nutritional Sciences Faculty Publications

Neurite outgrowth is essential for brain development and the recovery of brain injury and neurodegenerative diseases. In this study, we examined the role of the neurotrophic factor MANF in regulating neurite outgrowth. We generated MANF knockout (KO) neuro2a (N2a) cell lines using clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 and demonstrated that MANF KO N2a cells failed to grow neurites in response to RA stimulation. Using MANF siRNA, this finding was confirmed in human SH-SY5Y neuronal cell line. Nevertheless, MANF overexpression by adenovirus transduction or addition of MANF into culture media facilitated the growth of longer neurites in RA-treated N2a …

Whalesong 2020-09-24 (V.40 No.4), Mike Flunker, Baylee Schneider, Kenedy Williams, Sierra Lissick, Rosemarie Alexander, Heidi Pearson

Whalesong

No abstract provided.

Roosting Ecology Of A Declining Population Of Northern Long-Eared Bats (Myotis Septentrionalis) In The Ozark-St. Francis National Forest Of Arkansas, Kyle Norris Edmonds

Student Theses and Dissertations

Ecological and monetary values associated with bat species are immense. Unfortunately, these benefits are at risk as disease and habitat loss have resulted in significant declines of bat populations throughout the eastern United States. Wildlife biologists and managers work tirelessly to combat the effects of these threats. Collections of species-level data during surveys provide managers with invaluable information that can be used in identification of emerging population trends. This material can then be used to generate new habitat management plans or revise existing plans in order to address the objectives of primary management goals. This thesis outlines anthropogenic factors, interspecific …

Orientocardiochiles, A New Genus Of Cardiochilinae (Hymenoptera, Braconidae), With Descriptions Of Two New Species From Malaysia And Vietnam, Ilgoo Kang, Khuat Dang Long, Michael J. Sharkey, James B. Whitfield, Nathan P. Lord

Entomology Faculty Publications

For the first time in 21 years, a new genus of cardiochiline braconid wasp, Orientocardiochiles Kang & Long, gen. nov. (type species Orientocardiochiles joeburrowi Kang, sp. nov.), is discovered and described. This genus represents the ninth genus in the Oriental region. Two new species (O. joeburrowi Kang, sp. nov. and O. nigrofasciatus Long, sp. nov.) are described and illustrated, and a key to species of the genus, with detailed images, is added. Diagnostic characters of the new genus are analyzed and compared with several other cardiochiline genera to allow the genus to key out properly using an …

Global Convergence Of Covid-19 Basic Reproduction Number And Estimation From Early-Time Sir Dynamics, Gabriel G. Katul, Asaad Mrad, Sara Bonetti, Gabriele Manolia, Anthony J. Parolari

Civil and Environmental Engineering Faculty Research and Publications

The SIR (‘susceptible-infectious-recovered’) formulation is used to uncover the generic spread mechanisms observed by COVID-19 dynamics globally, especially in the early phases of infectious spread. During this early period, potential controls were not effectively put in place or enforced in many countries. Hence, the early phases of COVID-19 spread in countries where controls were weak offer a unique perspective on the ensemble-behavior of COVID-19 basic reproduction number inferred from SIR formulation. The work here shows that there is global convergence (i.e., across many nations) to an uncontrolled R_o=4.5 that describes the early time spread of COVID-19. This value …

Verification And Utility In The Arabic Commentaries On The Canon Of Medicine: Examples From The Works Of Fakhr Al-Dīn Al-Rāzī (D. 1210) And Ibn Al-Nafīs (D. 1288), Nahyan Fancy

History Faculty publications

Although over two dozen Arabic commentaries on the Canon of Medicine were composed between the twelfth and fourteenth centuries, historians of medicine have paid scant attention to them. Instead, these commentaries have often been dismissed as being uncritical expositions that further entrenched the dogma of Galenic/Avicennan medical theory. In this article, I shall show that in fact the opposite was the case for at least a subset of the Canon commentaries from this period. Fakhr al-Dīn al-Rāzī developed a new style of verification commentary across his philosophical corpus that he also deployed in his Canon commentary. Even though Fakhr al-Dīn …

Crosstalk Between The Antioxidant And Cell Wall Integrity Systems In Fungi By 2-Hydroxy-4-Methoxybenzaldehyde, Jong H. Kim, Kathleen L. Chan, Christina C. Tam, Luisa W. Cheng, Kirkwood M. Land

Pacific Faculty Work

We would like to comment on a recent study where the redox-modulatory anti-protozoal drug chloroquine has shown to trigger a crosstalk between the antioxidant and cell wall integrity systems in the yeast Saccharomyces cerevisiae. This note discusses the redox-active potential of the natural compound 2-hydroxy-4-methoxybenzaldehyde (2H4M) which could also serve as a potent redox-cycler in fungal (yeast, molds) pathogens. Using S. cerevisiae as a molecular tool, we determined how 2H4M negatively affected both the antioxidant and cell wall integrity systems of fungi, thus indicating a similar crosstalk between the two systems under 2H4M-induced toxicity. The crosstalk functions as a fungal …

Age Induced Modifications In The Persistency Of Voluntary Sway When Actively Tracking The Complex Motion Of A Visual Target, Haralampos Sotirakis, Nick Stergiou, Dimitrios A. Patikas, Vassilia Hatzitaki

Journal Articles

Movement persistency, reflected in systematic cycle to cycle fluctuations of a rhythmical task such as walking or voluntary sway, is compromised with increasing age, making older adults more susceptible to falls. In the present study, we tested whether it is possible to improve rhythmic voluntary sway persistency in old age by actively tracking the complex (i.e. persistent) motion of a visual target. Twenty healthy young and 20 older adults performed 132 cycles of anterior-posterior sway under two conditions: a) self-paced sway and b) sway while tracking the vertical motion of a complex visual target. The persistency of sway cycle amplitude …

Prevalence And Determinants Of Anemia Among Women Of Reproductive Age In Thatta Pakistan: Findings From A Cross-Sectional Study, Sumera Aziz Ali, Zahid Abbasi, Babar Shahid, Ghazal Moin, K Michael Hambidge, Nancy F. Krebs, Jamie E. Westcott, Elizabeth M. Mcclure, Robert L. Goldenberg, Sarah Saleem

Community Health Sciences

Background: Anemia is a major public health concern among women of reproductive age leading to high maternal mortality in low- and middle-income countries. Of the prior studies conducted in Pakistan, most focused on large urban areas and did not explore the determinants of anemia among women of reproductive age (WRA) across socio-demographic, dietary, reproductive, and biological domains. Thus, we aimed to study the prevalence and determinants of anemia among WRA in rural Pakistan.
Methods: We conducted a cross-sectional study in the Thatta district of Pakistan from September 2018 to January 2019 and enrolled 150 non-pregnant, married women. Data collectors administered …

Impact Of Metformin On Feeding, Behavior, And Metabolism In Drosophila Melanogaster., Erica E. Hassoun, Heba Kourhabi, Jason Bui Ho, Dae-Sung Hwangbo

Undergraduate Research Events

Metformin is a first-line drug used in the treatment of type II diabetes mellitus and is the 4th-most prescribed drug in the United States. It functions in lowering blood glucose levels and increasing insulin sensitivity. Despite its wide scale use, the degree to which it affects aspects of behavior and metabolism unrelated to diabetes is not fully understood.

Recent studies have attempted to fill this gap, particularly in the context of metformin’s impact on lifespan. We decided to extend this research by focusing on measurable behaviors as well as traits related to metabolism and physiology. Using the fruit fly Drosophila …

Choice Of Molecular Assay Determines Ranavirus Detection Probability And Inferences About Prevalence And Occurrence, Felicity J. Wynne, Robert Puschendorf, Mairi E. Knight, Stephen J. Price

School of Biological and Marine Sciences

Ranaviruses are emerging pathogens that can cause morbidity, mortality and population declines in ectothermic hosts; however, there is no standardized approach to diagnostics. Here, we compared the inter-assay variation and intra-assay precision among 2 commonly used quantitative PCRs (qPCRs), a conventional and a nested PCR assay (used as a gold standard), using laboratory-propagated ranavirus (FV3 and CMTV) and field-collected samples. A qPCR assay (‘Leung’) detected viral DNA in dilutions 2 orders of magnitude lower than other assays regardless of the viral lineage of the cultured isolate (FV3/CMTV). The second qPCR (‘Brunner’) was slightly more sensitive than the conventional PCR (‘Mao’ …