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2020

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Pengaruh Project Based Learning Terhadap Perilaku Prososial Anak Usia Dini, Santi Dianita, Triyono Triyono, Imron Arifin Sep 2020

Pengaruh Project Based Learning Terhadap Perilaku Prososial Anak Usia Dini, Santi Dianita, Triyono Triyono, Imron Arifin

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Early childhood needs to have prosocial behavior to socialize. Conventional learning causes low prosocial behavior. The purpose of this study was to determine the effect of project based learning on prosocial behavior of young children. This study uses a single subject research experimental design with three Group B kindergarten children as research subjects. Data collection using a rating scale prosocial behavior, showed an increase in prosocial behavior in all three subjects. The results of this study indicate that project based learning influences prosocial behavior of young children.


Efektivitas Model Project-Based Learning Terintegrasi Stem (Pjbl-Stem) Terhadap Keterampilan Berpikir Kreatif Siswa Kelas X, Jimmi Andrew Mamahit, Duran Corebima Aloysius, Hadi Suwono Sep 2020

Efektivitas Model Project-Based Learning Terintegrasi Stem (Pjbl-Stem) Terhadap Keterampilan Berpikir Kreatif Siswa Kelas X, Jimmi Andrew Mamahit, Duran Corebima Aloysius, Hadi Suwono

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Creative thinking skills are individual skills in using their thinking processes to generate new ideas. Creative thinking skills make students active in learning, able to express opinions, and process information easily. Creative thinking skills also enhance collaborative learning in which student-centered learning activities. One of the learning models that can be used is the STEM integrated Project Based Learning (PjBL-STEM) learning model. The research was conducted to determine the success of the PjBL-STEM model on students' creative thinking skills. This research was conducted in class X IPA SMAN 5 Malang with this type of research in the form of a …


Kompetensi Profesional Dan Pedagogik Guru Dalam Pengelolaan Pembelajaran Di Sekolah Dasar, Saraya Faridah, Ery Tri Djatmika, Sugeng Utaya Sep 2020

Kompetensi Profesional Dan Pedagogik Guru Dalam Pengelolaan Pembelajaran Di Sekolah Dasar, Saraya Faridah, Ery Tri Djatmika, Sugeng Utaya

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This study aims to study teacher competencies in managing learning, teacher professional strategies and learning in improving education quality. Descriptive research method with qualitative research. Data collection techniques are carried out through interviews, observation, and documentation studies. Based on the results of the study concluded from professional competence and pedagogical knowledge the teacher shows: (1) competencies needed by teachers in learning in preparing lesson plans, preparation of syllabus, planning media and learning resources accompanied by learning in accordance with the instructions provided, but there are some teachers who teach not make learning planning; (2) the teacher's professional strategy in implementing …


Isolated Central Nervous System Metastasis From Neuroendocrine Carcinoma Of The Cervix Without Pulmonary Metastasis, Fabiola Valenzuela, Sohum Desai Sep 2020

Isolated Central Nervous System Metastasis From Neuroendocrine Carcinoma Of The Cervix Without Pulmonary Metastasis, Fabiola Valenzuela, Sohum Desai

School of Medicine Publications

Neuroendocrine carcinoma of the cervix (NECC) accounts for 2% of all cervical cancers. Brain metastasis is rare, with few cases described in the literature, and is usually associated with preceding pulmonary metastasis. We describe an additional case of isolated brain metastasis without pulmonary metastasis from NECC and reflect on unique management.

A 37-year-old woman with a history of NECC presented with severe headache post-total hysterectomy with pelvic lymph node dissection. The computed tomography (CT) scan demonstrated obstructive hydrocephalus with several intra-axial lesions located in the pineal region, left cerebellar hemisphere, and left frontal operculum. A right frontal ventriculostomy was initially …


Transcriptomic Study For Identification Of Major Nitrogen Stress Responsive Genes In Australian Bread Wheat Cultivars, Nigarin Sultana, Shahidul Islam, Angela Juhasz, Rongchang Yang, Maoyun She, Zaid Alhabbar, Jingjuan Zhang, Wujun Ma Sep 2020

Transcriptomic Study For Identification Of Major Nitrogen Stress Responsive Genes In Australian Bread Wheat Cultivars, Nigarin Sultana, Shahidul Islam, Angela Juhasz, Rongchang Yang, Maoyun She, Zaid Alhabbar, Jingjuan Zhang, Wujun Ma

Research outputs 2014 to 2021

High nitrogen use efficiency (NUE) in bread wheat is pivotal to sustain high productivity. Knowledge about the physiological and transcriptomic changes that regulate NUE, in particular how plants cope with nitrogen (N) stress during flowering and the grain filling period, is crucial in achieving high NUE. Nitrogen response is differentially manifested in different tissues and shows significant genetic variability. A comparative transcriptome study was carried out using RNA-seq analysis to investigate the effect of nitrogen levels on gene expression at 0 days post anthesis (0 DPA) and 10 DPA in second leaf and grain tissues of three Australian wheat (Triticum …


Effects Of Germline And Somatic Events In Candidate Brca-Like Genes On Breast-Tumor Signatures, Weston R. Bodily, Brian H. Shirts, Tom Walsh, Suleyman Gulsuner, Mary-Claire King, Alyssa Parker, Moom Roosan, Stephen R. Piccolo Sep 2020

Effects Of Germline And Somatic Events In Candidate Brca-Like Genes On Breast-Tumor Signatures, Weston R. Bodily, Brian H. Shirts, Tom Walsh, Suleyman Gulsuner, Mary-Claire King, Alyssa Parker, Moom Roosan, Stephen R. Piccolo

Pharmacy Faculty Articles and Research

Mutations in BRCA1 and BRCA2 cause deficiencies in homologous recombination repair (HR), resulting in repair of DNA double-strand breaks by the alternative non-homologous end-joining pathway, which is more error prone. HR deficiency of breast tumors is important because it is associated with better responses to platinum salt therapies and PARP inhibitors. Among other consequences of HR deficiency are characteristic somatic-mutation signatures and gene-expression patterns. The term “BRCA-like” (or “BRCAness”) describes tumors that harbor an HR defect but have no detectable germline mutation in BRCA1 or BRCA2. A better understanding of the genes and molecular events associated with tumors being …


Study On The Grinding Time Duration Impact On The Properties Of Paper From Alternative Raw Materials, Z. K. Galimova Sep 2020

Study On The Grinding Time Duration Impact On The Properties Of Paper From Alternative Raw Materials, Z. K. Galimova

Technical science and innovation

Both raw and recycled fiber materials are used for paper production. The increase in percentage use of the latter is due to their paper-forming properties, availability and low cost. The article explores the possibility of using pulp from the inner layer of mulberry twig bark. Mulberry twigs, after removing leaves, which are the main raw material in silk production, have no practical industrial application. Recycling waste - mulberry branches - for the production of pulp is therefore relevant as it is aimed at solving raw material and environmental problems. The purpose of this work is to use local raw materials …


Coral Gardens Reef, Belize: A Refugium In The Face Of Caribbean-Wide Acropora Spp. Coral Decline, Lisa Greer, Tara Clark, Tanner Waggoner, James Busch, Thomas P. Guilderson, Karl Wirth, Jian-Xin Zhao, H. Allen Curran Sep 2020

Coral Gardens Reef, Belize: A Refugium In The Face Of Caribbean-Wide Acropora Spp. Coral Decline, Lisa Greer, Tara Clark, Tanner Waggoner, James Busch, Thomas P. Guilderson, Karl Wirth, Jian-Xin Zhao, H. Allen Curran

Geosciences: Faculty Publications

Caribbean Acropora spp. corals have undergone a decline in cover since the second half of the twentieth century. Loss of these architecturally complex and fast-growing corals has resulted in significant, cascading changes to the character, diversity, and available eco spaces of Caribbean reefs. Few thriving Acropora spp. populations exist today in the Caribbean and western North Atlantic seas, and our limited ability to access data from reefs assessed via long-term monitoring efforts means that reef scientists are challenged to determine resilience and longevity of existing Acropora spp. reefs. Here we used multiple dating methods to measure reef longevity and determine …


Prostitusi Online: Penjualan Suami Oleh Istri (Perubahan Relasi Gender Dan Seksualitas Di Era Digital), Vinita Susanti Sep 2020

Prostitusi Online: Penjualan Suami Oleh Istri (Perubahan Relasi Gender Dan Seksualitas Di Era Digital), Vinita Susanti

Jurnal Hukum & Pembangunan

This article discusses online prostitution in the digital age, by showing changes in gender relations between victims and perpetrators, which are analyzed with the view of radical feminists and Bourdieu's theory, symbolic violence. Women in gender ideology are placed as victims, so in this article there is social deconstruction, where women occupy positions as perpetrators. This change was demonstrated through an online prostitution case: the selling of a husband by a wife. The discussion begins with the case of online prostitution, women in reality studies: victims of online prostitution, the study of radical feminist thought and symbolic violence from Bourdieu's …


The Experiences Of Black Women In Diversity Roles At 4-Year Predominantly White Institutions, Tristen Brena� Johnson Sep 2020

The Experiences Of Black Women In Diversity Roles At 4-Year Predominantly White Institutions, Tristen Brena� Johnson

Theses and Dissertations

Many Black women professionals at predominantly White colleges and universities share similar experiences regarding racism, sexism, and classism at their institutions. However, there is a dearth of research regarding the experiences of Black women who specifically work in diversity related positions at four-year predominantly White institutions (PWI). The purpose of this study was to explore the lived experiences of Black women who hold diversity related roles at PWIs. For the purpose of this study, diversity positions were defined as roles held in housing and residence life as well as in multicultural affairs departments and centers. Using a qualitative research approach …


Needs Analysis For Mobile Learning Of Plant Structure And Development Topic, Ahya Mujahidin, Murni Sapta Sari, Suhadi Suhadi Sep 2020

Needs Analysis For Mobile Learning Of Plant Structure And Development Topic, Ahya Mujahidin, Murni Sapta Sari, Suhadi Suhadi

Jurnal Pendidikan Sains

Digital media has the potential to support learning, such as Mobile Learning. The fact show that students currently have not matched their ability to use digital media for the sake of obtaining information. The purpose of this study was to analyze the media learning needs of Plant Structure and Development material. This type of research is descriptive qualitative with observations and surveys. Research instruments in the form of observation sheets and questionnaires. This research was conducted from July to September 2019 at the Biology Education Study Program, FMIPA, UM. The research subjects consisted of 33 students and 1 lecturer. The …


Mind Mapping In The Argument Driven Inquiry (Adi) Model To Improve Students' Cognitive Learning Outcomes On Reaction Rate Topic, Mentari Arie Dian Safitri, Endang Budiasih, Siti Marfu’Ah Sep 2020

Mind Mapping In The Argument Driven Inquiry (Adi) Model To Improve Students' Cognitive Learning Outcomes On Reaction Rate Topic, Mentari Arie Dian Safitri, Endang Budiasih, Siti Marfu’Ah

Jurnal Pendidikan Sains

The purpose of this study was to determine the effect of mind mapping with Argument Driven Inquiry (ADI) model on student’s cognitive learning outcomes (CLO) in the rate of reaction material. This study was a quasi-experimental design with a 2x2 design factorial. The results showed that: (1) there were differences in CLO for students who were learned using ADI-mind mapping and ADI in the rate of reaction material; (2) there were differences in CLO for students with high initial abilities and students who have low initial abilities learned using ADI-mind mapping and ADI in the rate of reaction material; (3) …


Dampak Psbb Dan Psbb Transisi Di Dki Jakarta Dalam Pengendalian Covid-19, Hermawan Saputra, Nadilah Salma Sep 2020

Dampak Psbb Dan Psbb Transisi Di Dki Jakarta Dalam Pengendalian Covid-19, Hermawan Saputra, Nadilah Salma

Media Kesehatan Masyarakat Indonesia

The COVID-19 pandemic has negative impacts on various sectors so that Government wisdom in determining evidence-based intervention priorities becomes very important. DKI Jakarta Regional Government has chosen the Transitional PSBB policy as an effort economy relaxation but how effective the policy is in controlling COVID-19. The research finds out the impact of the implementation of the PSBB and Transitional PSBB (Large-Scale Social Restrictions) in DKI Jakarta as well as the health system capacity in the context of handling and controlling COVID-19. This is a qualitative study using desk research and expert studies on PSBB and its implementation. The case situation …


Perilaku Swamedikasi Pada Perokok Di Indonesia, Via Dolorosa Halilintar, Amal Chalik Sjaaf Sep 2020

Perilaku Swamedikasi Pada Perokok Di Indonesia, Via Dolorosa Halilintar, Amal Chalik Sjaaf

Media Kesehatan Masyarakat Indonesia

Self-Medication practices are considered to be a quick solution in treatment when a person can not access the formal health services, but on the other hand, this behavior can cast up the economic burden and health losses if not properly monitored. Meanwhile, smoking is seen as a negative behavior, which can also cause a double burden, both in terms of increased expenditure also has a negative effect on health. This study aims to describe self-medication behavior among smokers in Indonesia and the determinants that influence it. This study is a quantitative study using secondary data from the Indonesia National Socio-Economic …


A Document Analysis And Examination Of Attitudes Toward Transgender Membership Eligibility In Single-Sex, Greek-Letter, Social Fraternities And Sororities, William Wallace Weaver Sep 2020

A Document Analysis And Examination Of Attitudes Toward Transgender Membership Eligibility In Single-Sex, Greek-Letter, Social Fraternities And Sororities, William Wallace Weaver

Student Theses and Dissertations

Because the civil rights of the LGBT community have risen to the forefront in American culture since the turn of the twenty-first century, this study sought to analyze membership eligibility policies and attitudes of single-sex, Greek-letter, social fraternal organizations in regards to transgender individuals. Title IX of the United States Education Amendment of 1972 provides protection from discrimination by institutes of higher learning that receive federal financial assistance. However, section 1681 of Title IX provides an exemption for social fraternities and sororities with primary active membership of students enrolled at a shelter institution. This exemption allows social fraternal organizations to …


Quantitative Analysis Of Phytochemical Compounds In Barks And Leaves Of Okoubaka Aubrevillei Collected From Iwo, Southwestern Nigeria, Oluwatoyin Opeyemi Akintola, Adeboyin Funmi Aderounmu, Isaac Oluwaseyi Abiola, Kolawole Emmanuel Abodurin, Tunde Adeniran, Festus Agboola, Oluwayemisi Samuel Olokeogun Sep 2020

Quantitative Analysis Of Phytochemical Compounds In Barks And Leaves Of Okoubaka Aubrevillei Collected From Iwo, Southwestern Nigeria, Oluwatoyin Opeyemi Akintola, Adeboyin Funmi Aderounmu, Isaac Oluwaseyi Abiola, Kolawole Emmanuel Abodurin, Tunde Adeniran, Festus Agboola, Oluwayemisi Samuel Olokeogun

Journal of Bioresource Management

Okoubaka aubrevillei is an indigenous and sacred tropical tree in Africa. It is rare with allelopathic properties and has relatively little information available in terms of what is responsible for its usage for medicinal and traditional usage. The phytochemical screening and quantitative analysis of the compounds in the barks and leaves of Okoubaka aubrevillei was determined to ascertain and establish its earlier claimed usage as traditional and modern medicine. The most important classes of secondary metabolites (phytochemical compounds) specifically alkaloids, flavonoids, tannins, saponins, anthraquinnes, mucilages, oses, holosides, coumarin and glycosides were detected in both, the leaves and barks of the …


Midweek Memo, Georgia Southern University Sep 2020

Midweek Memo, Georgia Southern University

Midweek Memo

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The Montclarion, September 30, 2020, The Montclarion Sep 2020

The Montclarion, September 30, 2020, The Montclarion

The Montclarion

Student Newspaper of Montclair State University, Special Edition, Best of the Month: September


Studi Eksplorasi Perkuliahan Perkembangan Embrio Mamalia Matakuliah Struktur Perkembangan Hewan Ii, Ardiyas Robi Saputra, Mohamad Amin, Umie Lestari Sep 2020

Studi Eksplorasi Perkuliahan Perkembangan Embrio Mamalia Matakuliah Struktur Perkembangan Hewan Ii, Ardiyas Robi Saputra, Mohamad Amin, Umie Lestari

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This study aims to determine the teaching material requirements that will be developed in the topic of mammalian embryo development in SPH II course. This data collection of research uses questionnaire sheets to students and lecturer. The difficulties experienced by students during the SPH II lecture included the complexity of the topic and learning resources. Students assessed the teaching materials need to be develop and interested to use teaching material based on research. The conclusion of this study is necessary to develop module as teaching materials based on research results so that students can learn independently through intact material.


Research Practice And Productivity On Electronic Resources In India: Scientometrics Study Based On Scopus Database, Mohammad Rafiqur Rahman, Dr.V.P Khare Sep 2020

Research Practice And Productivity On Electronic Resources In India: Scientometrics Study Based On Scopus Database, Mohammad Rafiqur Rahman, Dr.V.P Khare

Library Philosophy and Practice (e-journal)

This paper aims to examine research practice and performance on the electronics resources in India during the year 2011 to 2020 on different parameters namely yearly research growth, relative growth rate and doubling time, forms of research, most prolific authors and Institutions, Collaborative country, degree of collaboration, and funding agency etc. The data of the current research paper about electronic resources indexed in the Scopus database have been retrieved. The records with topic search (includes Title, Abstract, Keywords and Keywords Plus) “Electronic resources” were extracted. MS Excel and VOS viewer have analyzed these data. The search result shows that a …


A Bibliometric Analysis Of Research Productivity On Diabetes Modeling And Artificial Pancreas 2001 To 2020, Karim A. Jabali, Murtaza Ashiq, Shakil Ahmad, Shafiq Ur Rehman Sep 2020

A Bibliometric Analysis Of Research Productivity On Diabetes Modeling And Artificial Pancreas 2001 To 2020, Karim A. Jabali, Murtaza Ashiq, Shakil Ahmad, Shafiq Ur Rehman

Library Philosophy and Practice (e-journal)

The prevalence of diabetes apparently increases all over the world. Thus, significant research works have been carried out in all aspects of the disease to control and mitigate its effects. Many researchers looked to the disease as a biomedical control engineering problem where the main task is identifying the model that can be used to mimic the healthy person's metabolism and therefore relieving the lives of millions of diabetics. This work aims to explore the dynamics of the produced scientific research in the area of diabetes modeling and control from a bibliometric method. In this work, a comprehensive bibliometric analysis …


Growth, Physiological And Biochemical Responses Of Winged Bean (Psophocarpus Tetragonolobus) Towards Different Shade Levels, Murthazar Naim Raai Sep 2020

Growth, Physiological And Biochemical Responses Of Winged Bean (Psophocarpus Tetragonolobus) Towards Different Shade Levels, Murthazar Naim Raai

Student Works (2020-2029)

Ambiguous evidence suggests that shade could regulate the indeterminate growth habit of winged bean (Psophocarpus tetragonolobus), an underutilized protein-rich legume from the tropics. This study was conducted to examine the effects of three different shade levels, including 60% (heavy shade), 30% (moderate shade), and 0% (as control) on 25 traits associated with morphological features, photosynthetic and agronomic characteristics of winged bean. The shade-house experiment was conducted using a completely randomized design. Collectively, approximately 80% of the studied variables displayed significant differences (P< 0.05) between at least two shade treatments. Shading generally showed the most pronounced effect on the physiological traits of the legume, whereby the stomatal conductance, photosynthetic and transpiration rates differed significantly (P< 0.05) among plants for all treatments. Overall, non-shaded plants were observed to have superior growth and physiological responses than the shaded plants, especially being significantly taller with higher stomatal conductance, photosynthetic and transpiration rates. Interestingly, the moderately shaded plants exhibited the highest yield per plant (28.9 g �} 1.47), which significantly differed from the non-shaded (23.8 g �} 1.06) and heavily shaded (21.4 g �} 1.48) plants. These findings suggested that winged bean plants can adapt to partial shaded conditions or canopy cover, making it a potential nitrogen-fixing cash crop which can be planted together with fruit and oil trees in commercial plantations. Given that there were no significant differences between the moderately shaded and heavily plants with respect to their seed protein content (P>0.05), this project also demonstrates that winged bean can grow and yield well while maintaining its protein content …


Effects Of Germline And Somatic Events In Candidate Brca-Like Genes On Breast-Tumor Signatures, Weston R. Bodily, Brian H. Shirts, Tom Walsh, Suleyman Gulsuner, Mary-Claire King, Alyssa Parker, Moom Roosan, Stephen R. Piccolo Sep 2020

Effects Of Germline And Somatic Events In Candidate Brca-Like Genes On Breast-Tumor Signatures, Weston R. Bodily, Brian H. Shirts, Tom Walsh, Suleyman Gulsuner, Mary-Claire King, Alyssa Parker, Moom Roosan, Stephen R. Piccolo

Faculty Publications

Mutations in BRCA1 and BRCA2 cause deficiencies in homologous recombination repair (HR), resulting in repair of DNA double-strand breaks by the alternative non-homologous end-joining pathway, which is more error prone. HR deficiency of breast tumors is important because it is associated with better responses to platinum salt therapies and PARP inhibitors. Among other consequences of HR deficiency are characteristic somatic-mutation signatures and gene-expression patterns. The term “BRCA-like” (or “BRCAness”) describes tumors that harbor an HR defect but have no detectable germline mutation in BRCA1 or BRCA2. A better understanding of the genes and molecular events associated with tumors being …


Konsep Kepemilikan Tanah Ulayat Masyarakat Adat Minangkabau, Fitrah Akbar Citrawan Sep 2020

Konsep Kepemilikan Tanah Ulayat Masyarakat Adat Minangkabau, Fitrah Akbar Citrawan

Jurnal Hukum & Pembangunan

Land is a very important factor in the life of the people of Indonesia, especially in the environment of the West Sumatra customary law community, where most of its population depend their lives and livelihoods from the land. In West Sumatra, in reality there are still acknowledged lands in the customary law community whose management, use and use are based on the provisions of local customary law and are recognized by the residents of the customary law community as their communal land. Ulayat Land Minangkanbau in the concept of ownership includes in the narrow sense that it is in the …


Annals Of The Hoồng Bàng Clan: From Ancient Legend To Modern Molecular Biology Evidence, Hoang Huu Phuoc Sep 2020

Annals Of The Hoồng Bàng Clan: From Ancient Legend To Modern Molecular Biology Evidence, Hoang Huu Phuoc

Asia-Pacific Social Science Review

The biography of the Hồng Bàng Clan is considered as a legend, a semi-historical document and an important part of the Viet’s cultural heritage. According to this work, the Viet people are the descendants of Shen Nong (an ancestor of the Han Chinese), migrating from China to the Red River Delta. A large number of scholars have built a Hundred Viet/ 百越 hypothesis, also known as “migration-from-the-north hypothesis” from this document. Throughout the long history, Hồng Bàng legend has created popular misunderstandings of the Viet about their origin and misconceptions for later researchers of various subjects, such as literature, linguistics, …


Psychological Distress Of Filipino Deaf: Role Of Environmental Vulnerabilities, Self-Efficacy, And Perceived Functional Social Support, Marcella L. Sintos Sep 2020

Psychological Distress Of Filipino Deaf: Role Of Environmental Vulnerabilities, Self-Efficacy, And Perceived Functional Social Support, Marcella L. Sintos

Asia-Pacific Social Science Review

Researches on Deaf mental health show that Deaf individuals are two to three times more vulnerable to psychological distress compared to their hearing counterparts because they have been exposed to several environmental vulnerabilities. Using the assumptions of stress-vulnerability-protective factors model of Liberman (2008), this study looked into the moderating role of protective factors (general self-efficacy and perceived functional social support) on the effect of vulnerabilities in the psychological distress of 120 self-contained Deaf college students aged 18 to 25 (M=21.83; SD=4.11). Results show that (a) there is a non-significant relationship between environmental vulnerabilities and psychological distress, and (b) general self-efficacy …


Diffusing Social Innovations In Philippine Apitourism, John Paolo R. Rivera, Lailani L. Alcantara, Anahata Harikumar Sep 2020

Diffusing Social Innovations In Philippine Apitourism, John Paolo R. Rivera, Lailani L. Alcantara, Anahata Harikumar

Asia-Pacific Social Science Review

No abstract provided.


Contributors, Global Insight Editorial Team Sep 2020

Contributors, Global Insight Editorial Team

Global Insight

No abstract provided.


Gay Rights, Religious Liberty, And The Misleading Racism Analogy, Andrew Koppelman Sep 2020

Gay Rights, Religious Liberty, And The Misleading Racism Analogy, Andrew Koppelman

BYU Law Review

No abstract provided.


Exploration Of The Neisseria Resistome Reveals Resistance Mechanisms In Commensals That May Be Acquired By N. Gonorrhoeae Through Horizontal Gene Transfer, Michael A. Fiore, Jordan C. Raisman, Narayan H. Wong, André O. Hudson, Crista B. Wadsworth Sep 2020

Exploration Of The Neisseria Resistome Reveals Resistance Mechanisms In Commensals That May Be Acquired By N. Gonorrhoeae Through Horizontal Gene Transfer, Michael A. Fiore, Jordan C. Raisman, Narayan H. Wong, André O. Hudson, Crista B. Wadsworth

Articles

Nonpathogenic Neisseria transfer mutations encoding antibiotic resistance to their pathogenic relative Neisseria gonorrhoeae. However, the resistance genotypes and subsequent phenotypes of nonpathogens within the genus have been described infrequently. Here, we characterize the minimum inhibitory concentrations (MICs) of a panel of Neisseria (n = 26)—including several commensal species—to a suite of diverse antibiotics. We furthermore use whole genome sequencing and the Comprehensive Antibiotic Resistance Database Resistance Gene Identifier (RGI) platform to predict putative resistance-encoding mutations. Resistant isolates to all tested antimicrobials including penicillin (n = 5/26), ceftriaxone (n = 2/26), cefixime (n = 3/26), tetracycline (n = 10/26), azithromycin (n …