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Maternal Preventive Dental Services Utilization: The Role Of Preconception Oral Health Counseling In And The Association With Birth Outcomes: Evidence From South Carolina Prams, Monique Johnette Williams

Theses and Dissertations

ABSTRACTThe purpose of this study is to examine maternal preventive dental services utilization by analyzing the role of preconception oral health counseling in utilization of dental cleaning services before or during pregnancy and the association of utilization with preterm birth (<37 weeks) and small for gestational age (SGA) (same sex newborns having birth weight for gestational age below the 10th percentile of the reference population as defined by the World Health Organization (WHO)). Studies suggest that unfavorable maternal oral conditions have significance in birth outcomes, specifically periodontal disease (periodontitis), an oral inflammatory condition which is shown to be a risk factor for preterm birth and low birth weight (Dortbudak et al., 2005; Guimarães et al., 2012; Tejada et al., 2012). Dental cleaning before and during pregnancy is effective in the prevention of oral disease including gingivitis and periodontitis (Johnson et al., 2006; Kurien et al., 2013; Steinberg et al., 2013).

Cross-sectional 2012-2015 data from the South Carolina Pregnancy Risk Assessment Monitoring System (SC PRAMS) survey, a population-based surveillance system on prenatal, perinatal and postpartum experiences of resident mothers who recently delivered a live-born infant, were analyzed using weighted analyses in SAS. Analyses included demographic univariate analyses, Rao-Scott Chi-squared tests of significance to study differences between groups, and multivariate logistic …

Metaphysics & Morals In Canadian Criminal Justice: A Pragmatic Analysis Of The Conflict Between Neuroscience And Retributive Folk Psychology, Sarah Greenwood

LLM Theses

The retributive justification of Canadian criminal law contains several assumptions about human nature that conflicts with what neuroscience has established regarding human behavior and the function of rationality. Interdisciplinary discourse on this conflict between law and neuroscience has unnecessarily implicated the free will debate and is further stagnated by epistemic cultural differences between the two disciplines. To avoid these roadblocks, this thesis applies the methodological principles of pragmatic philosophy. Rather than asking which description of human nature is true, pragmatic inquiry focuses on the difference either would make in practice. This analysis reveals that retributive folk psychology in practice causes …

Biosimilars: The Quest For A Rational Regulatory And Intellectual Property Approach In Canada, Elizabeth S. Dipchand

LLM Theses

Biologics and biosimilars represent the promise for more effective treatments of many diseases. International treaty obligations influenced heavily by the biopharmaceutical industry and advanced through the international trade agenda may lead to an imbalance between incentivizing innovation and the public interest. Canada’s implementation of its obligations into national patent and regulatory laws encourages aggressive biologic patent protection strategies that, coupled with linked regulatory assessments, may establish compounding layers of exclusion that disproportionately disincentivizes both the biologics innovation and biosimilar development. This comparative analysis addresses the progression of international obligations and the way in which they have been implemented into Canada’s …

Hive Minded: Like Neurons, Honey Bees Collectively Integrate Negative Feedback To Regulate Decisions, Talia M. Borofsky , '18, Victor J. Barranca, Rebecca Z. Zhou , '19, D. Von Trentini, R. L. Broadrup, C. Mayack

Mathematics & Statistics Faculty Works

Collective decision making is essential for multicellular and self-organized society coordination, but how this occurs when most of the individuals have limited knowledge of the external environment remains elusive. Using empirical data to inform a neuroscience-based firing-rate model, we found that integration of negative feedback and network dynamics in a honeybee, Apis mellifera, hive demonstrates strong similarities to the neuronal interactions of the human brain, where very brief perturbations of feedback in the system result in more rapid and accurate decisions. We show that honey bees used an inhibitory ‘stop’ signal towards dancing honey bees that reduced both waggle dancing …

Headwaters Fed By Subterranean Ice: Potential Climate Refugia For Mountain Stream Communities?, Lusha M. Tronstad, Scott Hotaling, J. Joseph Giersch, Oliver J. Wilmot, Debra S. Finn

College of Natural and Applied Sciences

Near-term extirpations of macroinvertebrates are predicted for mountain streams worldwide as a warming climate drives the recession of high-elevation ice and snow. However, hydrological sources likely vary in their resistance to climate change, and thus streams fed by more resistant sources could persist as climate refugia for imperiled biota. In 2015-2016, we measured habitat characteristics and quantified macroinvertebrate community structure along 6 alpine streams in the Teton Range, Wyoming, USA. Strong differences in habitat characteristics (e.g., temperature, bed stability, conductivity) confirmed 3 major stream sources: surface glaciers, perennial snowfields, and subterranean ice. Subterranean ice-fed streams - termed "icy seeps"- appear …

Ipulse: October 2020, Lynn University

Student Newspapers

Issues:

• October 5, 2020: #OscarsSoWhite to Oscars So Fresh; Newsflash: Patriotism is Not Inclusive; Constitution Day. Your Voice, Your Vote; Musical Theater Showcase
• October 12, 2020: Your Voice, Your Vote; Can iPhones Contact-Trace COVID-19, COVID-19 is Completely Changing Consumer Behavior; Social Distancing at Lynn University; All Clear for Landing
• October 19, 2020: Scheduling Success; Zoom is Coming to a TV Near You; Making Sure Your Vote Counts; Inclusivity is Not Political; Lynn Bucks are Back; Netflix Receives Intense Backlash for "Cuties"
• October 26, 2020: The Franchise Bachelor Casts the First Black American Lead; Unwritten Rules of Baseball; Littering Pandemic; Tips …

Risk Factors For Hospital Admission Among Covid-19 Patients With Diabetes: A Study From Saudi Arabia, Asirvatham A. Robert, Abdullah Bin Matar, Ali Algarni, Haneen Alkubedan, Turki Alharbi, Afrah Al Amro, Seham A. Alrashidi, Mohamed Al Dawish

Saudi Medical Journal

Objectives: To elucidate the risk factors for hospital admission among COVID-19 patients with type 2 diabetes mellitus (T2DM). Methods: This retrospective study was conducted at the Prince Sultan Military Medical City, Riyadh, Saudi Arabia between May 2020 and July 2020. Out of 7,260 COVID-19 patients, 920 were identified as T2DM. After the exclusion process, 806 patients with T2DM were included in this analysis. Patients’ data were extracted from electronic medical records. A logistic regression model was performed to estimate the risk factors of hospital admission. Results: Of the total of 806 COVID-19 patients with T2DM, 48% were admitted in the …

Legislative Brief, Tn Ready Test Development, Process And Costs, Tennessee. Comptroller Of The Treasury.

Office of Research and Education Accountability

No abstract provided.

Dean's Research Newsletter, October 2020, Jerry L. Nadler

SOM Dean's Research Newsletter

No abstract provided.

Agent-Based Modelling Of Values: The Case Of Value Sensitive Design For Refugee Logistics, Christine Boshuijzen-Van Burken, Ross J. Gore, Frank Dignum, Lamber Royakkers, Phillip Wozny, F. Leron Shults

VMASC Publications

We have used value sensitive design as a method to develop an agent-based model of values in humanitarian logistics for refugees. Schwartz’s theory of universal values is implemented in the model in such a way that agents can make value trade-offs, which are operationalized into a measure of refugee wellbeing and a measure of public opinion about how the refugee logistics is being handled. By trying out different ‘value scenarios’, stakeholders who are responsible for, or involved in refugee logistics can have insights into the effects of various value choices. The model is visualized and made usable as a platform …

Removal Of Water Binding Proteins From Dentin Increases The Adhesion Strength Of Low-Hydrophilicity Dental Resins, Ana Paula Farina, Doglas Cecchin, Cristina M. P. Vidal, Ariene A. Leme-Kraus, Ana K. Bedran-Russo

School of Dentistry Faculty Research and Publications

Objectives

To investigate the role of proteoglycans (PGs) on the physical properties of the dentin matrix and the bond strength of methacrylate resins with varying hydrophilicities.

Methods

Dentin were obtained from crowns of human molars. Enzymatic removal of PGs followed a standard protocol using 1 mg/mL trypsin (Try) for 24 h. Controls were incubated in ammonium bicarbonate buffer. Removal of PGs was assessed by visualization of glycosaminoglycan chains (GAGs) in dentin under transmission electron microscopy (TEM). The dentin matrix swelling ratio was estimated using fully demineralized dentin. Dentin wettability was assessed on wet, dry and re-wetted dentin surfaces through water …

Phase 1 Study Of The Mdm2 Antagonist Ro6839921 In Patients With Acute Myeloid Leukemia, Geoffrey L Uy, Sarit Assouline, Anne-Marie Young, Steven Blotner, Brian Higgins, Lin-Chi Chen, Karen Yee

2020-Current year OA Pubs

In acute myeloid leukemia (AML), TP53 mutations and dysregulation of wild-type p53 is common and supports an MDM2 antagonist as a therapy. RO6839921 is an inactive pegylated prodrug of the oral MDM2 antagonist idasanutlin (active principle [AP]) that allows for IV administration. This phase 1 monotherapy study evaluated the safety, pharmacokinetics, and pharmacodynamics of RO6839921 in patients with AML. Primary objectives identified dose-limiting toxicities (DLTs) and maximum tolerated dose (MTD). Secondary objectives assessed pharmacokinetic, pharmacodynamic, and antileukemic activity. A total of 26 patients received 120-300 mg AP of idasanutlin. The MTD was 200 mg, with DLTs at 250 (2/8 patients) …

Testing The Motivational Tradeoffs Between Pathogen Avoidance And Status Acquisition, Mitch Brown, Donald F. Sacco

Psychological Science Faculty Publications and Presentations

To reduce disease transmission through interpersonal contact, humans have evolved a behavioral immune system that facilitates identification and avoidance of pathogens. One behavioral strategy in response to pathogenic threat is the adoption of interpersonal reticence. However, reticence may impede status acquisition. This program of research tested whether activating pathogen-avoidant motives through priming fosters reticence related to status, namely disinterest in pursuing a group leadership position (Study 1) or disinterest in accepting a group leadership position bestowed onto them (Study 2). Individuals high in germ aversion were particularly interested in pursuing leadership as a form of status, with disease salience unexpectedly …

Mode Analysis And Applications Of Three-Layer Step-Index And Depressed-Core Optical Fibers, Xiaokang Lian

Doctoral

Optical fibersplay important roles in telecommunication, imaging, sensing, lasers and amplifiers. The rapid development of fiberopticsover the past decades has beenunderpinnedbyvarious designs of the optical fibers and bythe rapid improvement of the understanding of the waveguiding mechanismsand associated models. According to the cross-section refractive index distribution, optical fibers can be generally classified into four basic types: two-layer step-index fiber, three-layer step-index fiber, three-layer depressed-core fiber and hollow-core fiber.Among these four basic fibertypes,the modeproperties and the applications of the three-layer step-index and depressed-core fibers have notbeensufficiently investigated. This thesis presents a detailedmode analysis in three-layer step-index and depressed-core fibers and their …

Carbosilane Dendrimers: Drug And Gene Delivery Applications, Navid Rabiee, Shokooh Ahmadvand, Sepideh Ahmadi, Yousef Fatahi, Rassoul Dinarvand, Mojtaba Bagherzadeh, Mohammad Rabiee, Mohammadreza Tahriri, Lobat Tayebi, Michael R. Hamblin

School of Dentistry Faculty Research and Publications

Carbosilane dendrimers are a particular type of dendrimer structure that has been used as delivery vehicles for drugs and nucleic acids. They have a defined structure according to their generation number, and their terminal groups can be rendered cationic or anionic. The cationic charges can address the limitation of electrostatic repulsion between the negatively charged phosphate groups of nucleic acids and negatively charged cell membranes. Specific drugs can be loaded into the central part of the dendrimer or attached at the exterior, and the overall positive charge may improve the efficacy of anti-inflammatory drugs. One promising feature of dendrimers is …

Clonal Hematopoiesis: Mechanisms Driving Dominance Of Stem Cell Clones, Grant A Challen, Margaret A Goodell

2020-Current year OA Pubs

The discovery of clonal hematopoiesis (CH) in older individuals has changed the way hematologists and stem cell biologists view aging. Somatic mutations accumulate in stem cells over time. While most mutations have no impact, some result in subtle functional differences that ultimately manifest in distinct stem cell behaviors. With a large pool of stem cells and many decades to compete, some of these differences confer advantages under specific contexts. Approximately 20 genes are recurrently found as mutated in CH, indicating they confer some advantage. The impact of these mutations has begun to be analyzed at a molecular level by modeling …

Whitworth Today Fall 2020, Whitworth University

Whitworth Alumni and Bulletin Publications

No abstract provided.

The Status Of Northern Flying Squirrels In The Lower Peninsula Of Michigan, Phathit Renas

Student Summer Scholars Manuscripts

Being able to determine the presence of a species is imperative to proper wildlife management. This is especially true if the species is sensitive or endangered. Common methods of surveying like live trapping are invasive, labor-intensive, and often fail to give sufficient detection rates. New methods utilizing technological advancements give the opportunity to survey more effectively for species. We conducted a comparison of three trapping methods with the U.S. forest service to determine the viability of each for surveying northern flying squirrels (Glaucomys sabrinus) which is a species of concern. We compared live trapping and two noninvasive techniques, camera trapping, …

Physical And Metabolic Changes After Ileal Pouch-Anal Anastomosis: A Case Study, Jacob Erickson, Patrick Harty, Paul Molling, Richie Stecker, Chad Kerksick, Andrew Jagim

Faculty Scholarship

This case study examined changes in body composition, resting metabolic rate (RMR), aerobic capacity, and daily physical activity in a patient who had ulcerative colitis and underwent ileal pouch-anal anastomosis (IPAA) surgery. Body composition, RMR, and peak oxygen consumption (VO2peak) were assessed prior to surgery and four, eight, and 16 weeks after IPAA surgery. Daily physical activity data were extracted from a wrist-worn activity tracker preoperatively and 16 months postoperatively. At baseline, total body mass was 95.3 kg; body fat, 11.6%; lean body mass, 81.1 kg; RMR, 2416 kcal/d; and VO2peak, 42.7 mL/kg/min. All values decreased from baseline at four …

Synthesis And Design Of Novel Polymer Grafted Nanoparticles Relevant To Drug Delivery Vehicles For Biomedical Applications, Maan Abduldiyem Hassan Al-Ali

Theses and Dissertations

The modification of inorganic nanoparticles with organic polymer chains has become a significant field of study for the engineering of advanced nanocomposite materials. This dissertation presents the design, synthesis, and characterization of novel polymer grafted silica nanoparticles as new strategies to combat bacterial resistance. Described herein is the synthesis of monomers that have been graft polymerized onto silica nanoparticles that can be used as a delivery drug vehicle for biomedical applications. The polymerization of these monomers was performed via reversible addition-fragmentation chain transfer (RAFT) polymerization. The molecular design of the RAFT agents that are attached to the surfaces of the …

Talkin’ Black And Sounding Gay: An Examination Of The Construction Of A Multiplex Identity Via Intraspeaker Variation, Brianna R. Cornelius

Theses and Dissertations

Gay African-American men hold membership in at least three groups – Gay, Black, and Male – that are grounded in ideologies and which provide linguistic resources that are complex and potentially conflicting. As such, these men exist at the cross-section of socio-cultural groups whose perspectives and presentations are often framed in opposition to one another. This dissertation seeks to explore the ways in which such complex identities are created through the use of language. Specifically, this project will investigate how a Gay Black man (GBM) constructs his complex identity over the course of several interviews/conversations in which topic and interlocutor …

Reproductive Compatibility Among Populations And Host‐Associated Lineages Of The Common Bed Bug (Cimex Lectularius L.), Zachary C. Devries, Richard G. Santangelo, Warren Booth, Christopher G. Lawrence, Ondřej Balvín, Tomáš Bartonička, Coby Schal

Entomology Faculty Publications

As populations differentiate across geographic or host‐association barriers, interpopulation fertility is often a measure of the extent of incipient speciation. The bed bug, Cimex lectularius L., was recently found to form two host‐associated lineages within Europe: one found with humans (human‐associated, HA) and the other found with bats (bat‐associated, BA). No unequivocal evidence of contemporary gene flow between these lineages has been found; however, it is unclear whether this is due to an inability to produce viable “hybrid” offspring. To address this question and determine the extent of compatibility between host‐associated lineages, we set up mating crosses among populations of …

Faculty Senate Chronicle For October 1, 2020, Heather M. Loughney

The University of Akron Faculty Senate Chronicle

Minutes for the regular meeting of The University of Akron Faculty Senate on October 1, 2020

Antisemitism As An Underlying Precursor To Violent Extremism In American Far-Right And Islamist Contexts, Alexander Meleagrou-Hitchens, Bennett Clifford, Lorenzo Vidino, Program On Extremism, George Washington University, National Counterterrorism Innovation, Technology, And Education Center

Reports, Projects, and Research

Antisemitism is pervasive throughout several categories of American extremist movements, both violent and non-violent. American extremists incorporate antisemitic tropes and narratives in every level of their worldviews, using them to help construct “us/them” dichotomies and wide-sweeping conspiracies that are essential to their movements. During the past several decades, the American extremist movements that have been among the most violent—specifically, far-right and jihadist groups—have used antisemitism to target Jewish people, Jewish houses of worship, Jewish community institutions, and Americans supporting the Jewish state of Israel. Antisemitism, as a belief and world-structuring theory, can at times serve as a gateway issue for …

Cosm Diversity & Inclusion Newsletter, Georgia Southern University

College of Science & Mathematics: News & Publications (2012-2022)

Welcome!

The Diversity & Inclusion Newsletter is delivered monthly via email during the fall and spring semesters and is always available on the new COSM D&I webpage. Send contributions and suggestions to any of the COSM D&I Ambassadors (list at the bottom of the newsletter and on the webpage).

This Month’s Theme: Gender & Sexuality

"STEM: More LGBTQIA+ role models needed! But will coming out cost you your career?”

Fall 2020 Fast Facts, Georgia Southern University

Student Enrollment Infographics (2017-2022)

No abstract provided.

Topology-Guided Roadmap Construction With Dynamic Region Sampling, Read Sandström, Diane Uwacu, Jory Denny, Nancy M. Amato

Department of Math & Statistics Faculty Publications

Many types of planning problems require discovery of multiple pathways through the environment, such as multi-robot coordination or protein ligand binding. The Probabilistic Roadmap (PRM) algorithm is a powerful tool for this case, but often cannot efficiently connect the roadmap in the presence of narrow passages. In this letter, we present a guidance mechanism that encourages the rapid construction of well-connected roadmaps with PRM methods. We leverage a topological skeleton of the workspace to track the algorithm's progress in both covering and connecting distinct neighborhoods, and employ this information to focus computation on the uncovered and unconnected regions. We demonstrate …

Volume 4, Nova Southeastern University

be Still

No abstract provided.

The Medicinal Power Of Small Celebrations, Kristina Fritz

be Still

This personal essay provides a first-hand account of a patient and their family celebrating a change in perspective brought about by experiencing clinical studies/medicine. The author infers that celebrations throughout the medical journey could have a medicinal effect on their own for the patient and their families.

Joy In The Mourning, Ludonir Sebastiany Md, Ms

be Still

No abstract provided.