Digital Commons Network^™

Improving Transition To Adult Care: Assessing Health Insurance Literacy In Adolescent Patients With Congenital Heart Disease, Kaitlyn V. Mudge

Doctor of Nursing Practice Final Manuscripts

Background: With advances in surgery and medical management, 95% of children with congenital heart disease (CHD) survive into adulthood. Transition to adult care is an intricate process. Up to 60% of adolescents fail to follow through with cardiology care, facing three times the risk of needing emergency services. Only 25% of young adults with CHD knew of the need to change their care to an adult provider and to acquire health insurance as an adult. One barrier to successful transition is a lack of insurance coverage and limited insurance health literacy. Higher insurance literacy is associated with increased utilization …

Intervention Levers For Stunting Reduction In Indonesia: Evidence From The 2023 Indonesian Health Survey Data, Iwan Ariawan, Hafizah Jusril, Zahra Izza Afifa, Azka Fitri, Elmarizha Sekar Utami, Mikail Hasan, Dwi Puspasari

Kesmas

Stunting remains the largest public health challenge among macro-nutrition problems in Indonesia, affecting almost a quarter of children under five in 2023. The prevalence is considered high according to the World Health Organization standard. This study analyzed 15 aggregated provincial variables from the 2023 Indonesian Health Survey using Structural Equation Modeling (SEM), focusing on determinants of stunting among children under two to identify primary intervention levers. Findings indicated that intervention urgency should focus on the first 1,000 days, particularly the steep increase in stunting prevalence observed in the 12–24-month age range. While the highest prevalence is in Eastern provinces (e.g., …

Makna Simbolik Dan Memori Pascakolonial Dalam Cyanotype Fusion Dialogue “Trade Of Faith” Karya Budi Agung Kuswara: Kajian Semiotika Roland Barthes, Wisesa Abrar Mufid Munawwar Wahyuono, A. Syarifuddin Rohman

Journal of Language, Literature, and Arts

The cyanotype artwork Fusion Dialogue: Trade of Faith by Budi Agung Kuswara represents a contemporary art practice that combines cyanotype techniques and mixed media to construct visual narratives of colonialism, trade, spirituality, and cultural identity. This study aims to identify the visual symbols embedded in the artwork and analyze their meanings based on Roland Barthes’ semiotic theory. A descriptive qualitative approach was employed, with the researcher serving as the primary instrument. Data were collected through observation, documentation, interviews with the artist, and a literature review. Analysis involved symbol identification as well as denotative, connotative, mythological, and aesthetic analyses. The findings …

Developing An Effective And Sustainable Institutional Model For Water Resource Management In ‘Nusantara’ (The New Capital City Of Indonesia), Witra Apdhi Yohanitas, Arif Ramadhan, Tania Andari, Nicco Plamonia, Muhammad Akbar Pribadi, Riardi Pratista Dewa, Hery Wibowo, M. Hasnan Atlandi

BISNIS & BIROKRASI: Jurnal Ilmu Administrasi dan Organisasi

The development of 'Nusantara', the new capital city of Indonesia (IKN), is a strategic effort by the government of Indonesia to advance infrastructure development and management. However, ensuring effective and sustainable water resource management remains a major challenge, particularly amid climate change, population growth, and increasing industrial demand. This study aims to develop a sustainable water resource management model to support IKN effectively. It applies a qualitative descriptive and comparative approach through interviews and policy analysis to identify the needs and challenges in water resource management, while also assessing the potential and risks of the proposed model. The findings indicate …

Pernicious Anemia Presenting As Pseudothrombotic Microangiopathy: A Case Report, Sai Sushrutha M Vemula, Shreeya Adhikari, Shreya Motkur, Alfarooq Alshaikhli, Borys Hrinczenko

School of Medicine Publications

Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening thrombotic microangiopathy (TMA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end-organ dysfunction, with high untreated mortality that can be effectively reduced with timely plasma exchange (PLEX) and immunosuppressive therapy. However, several conditions can produce a clinically similar pseudo-TMA picture, among which severe vitamin B12 deficiency is an underrecognized and potentially treatable mimic that occurs due to ineffective intramedullary erythropoiesis, megaloblastic fragmentation of structurally abnormal erythrocytes, and pancytopenia in the absence of true endothelial injury or ADAMTS13 deficiency. We present a 74-year-old female patient who presented with altered mental status, bradycardia, and severe …

Perceptual And Geometric Advances In Crowd Simulation, Bilas Talukdar

Dissertations

Simulating realistic crowd motion remains a fundamental challenge in computer graphics and multi-agent systems, as it requires modeling both physically plausible interactions and perceptually natural behaviors. Existing crowd simulation methods typically employ simplified geometric abstractions, most commonly circular agent representations, and model navigation using either analytical interaction formulations (e.g., force, velocity, or constraint-based methods) or learned policies derived through reinforcement learning. Despite their effectiveness, these approaches often overlook detailed geometric structure and do not explicitly account for perceptual realism. This dissertation addresses these challenges by improving the realism of virtual crowd simulation through two key advancements: perceptual preference learning and …

Principles Of Privacy And Security In Artificial Intelligence And Applications, Khang Tran

Dissertations

Modern artificial intelligence (AI) systems have transformed critical domains such as healthcare, software engineering, finance, and the legal system. Despite their broad impact, concerns about trustworthiness, especially regarding privacy and security, remain major obstacles to wider adoption. Addressing these concerns requires both a systematic understanding of the privacy and security risks inherent in AI systems and the development of principled foundations for trustworthy AI that safeguard client privacy and security. This goal is particularly challenging because of the complexity of modern large-scale AI systems, the trade-offs between privacy and model utility, and the need to simultaneously ensure other important properties …

Mechanics And Physical Attributes Of Nature-Based Alterations: Rock Reinforcement And Urban Heat Island Assessment, Mary Chikondi Ngoma

Dissertations

Ground improvement is critical to geotechnical and geo-engineering systems, where modification of the properties of geomaterials (rocks and soils) is required to maintain stability and prevent failure of infrastructure installed within and around them. This need has become increasingly important with rapid urbanization and population growth, which intensify demands on surface and subsurface systems and further challenge the performance of supporting geomaterials. As a result, there is growing interest in nature-based solutions, particularly biologically mediated processes such as biocementation, which can enhance the physical, hydraulic, and mechanical properties of geomaterials while offering environmentally sustainable alternatives to conventional ground improvement techniques. …

Glass Transition Temperature Of Plga Nanoparticles And The Application In Drug Delivery, Guangliang Liu

Dissertations

The glass transition temperature (T_g) of poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles plays a crucial role in governing molecular mobility, diffusion, and consequently, drug release kinetics. However, the interaction among residual surfactant, drug effect, nanoscale confinement, and release medium on T_g remains insufficiently characterized. This study aims to bridge this gap by correlating the thermal behavior of PLGA nanoparticles with their drug release behavior under physiologically relevant conditions.

In the present study, PLGA nanoparticles were synthesized using both nano-emulsion and surfactant-free nano-precipitation approaches. The influence of residual surfactants - poly(vinyl alcohol) (PVA) and didodecyldimethylammonium bromide (DMAB) - was systematically …

Membrane-Engineered Nanotherapeutic Platforms For Drug Delivery: Hollow Fiber Membrane Synthesis Of Lipid Nanoparticles, Biomimetic Nanocarriers, And Nanobubbles, Zhixiang Liu

Dissertations

Lipid-based nanocarriers have emerged as a cornerstone technology for RNA therapeutics, enabling effective intracellular delivery for applications ranging from vaccination to gene regulation. However, current manufacturing approaches, particularly microfluidic-based platforms, face inherent limitations in scalability, throughput, and structural tunability due to their reliance on confined channel geometries and restricted mixing architectures. Addressing these challenges requires fundamentally new strategies that decouple nanoparticle formation from traditional microscale flow constraints while maintaining precise control over physicochemical properties.

This dissertation presents a comprehensive framework for the design, engineering, and application of advanced lipid-based nanocarriers, centered on a hollow fiber membrane (HFM)—assisted nanopore-mediated assembly platform. …

Parameter Density Estimation For Cardiac Electrophysiology Models Using Data Consistent Deep Learning, Michael Luo

Dissertations

Mathematical models of biological rhythms and excitable systems can provide insights into mechanisms underlying cardiac electrical dynamics. However, estimating the parameters of these models from experimental observations is often difficult due to noise, heterogeneity, and unobserved variables. For example, in an electrocardiogram (ECG) recording, information about the electrical properties of different regions of the heart is compressed into a single voltage trace. Additionally, variability within these signals may contain important information about population heterogeneity, regional differences in electrophysiology, and time-dependent modulation.

This dissertation develops, explores, and evaluates methods that perform feature-based distributional inference for complex nonlinear dynamical systems. The objective …

Transcranial Ac Modulation Of Cerebellar Nuclear Activity In Awake Animals, Nuran Kavakli

Dissertations

Entrainment of cerebellar nuclear (CN) cells via cerebellar transcranial alternating current stimulation (ctACS) has been reported in animals under ketamine/xylazine anesthesia. Our main objective was to demonstrate modulation of CN activity in unanesthetized, freely moving animals using ctACS. Multi-channel carbon-fiber electrodes were implanted into the interpositus nucleus for recording multi-unit (MU) activity, and thin-film electrodes were implanted subcutaneously over the posterior cerebellum for stimulation. A frequency-domain-based metric was developed to quantify modulation from MU signals. The results demonstrated modulation in a wide range of frequencies (4 Hz-300 Hz) as in anesthetized animals. In contrast, the amplitude of the peak in …

Enhancing Physiological Complexity Through Mindfulness: A Wearable-Based Intervention For First Responders And Their Partners, Thurmon Lockhart, Rahul Soangra, Christopher W. Frames, Sun-Kyung Lee, Amberlee Martin, Susanne Lee, Abigail H. Gewirtz

Physical Therapy Faculty Articles and Research

Background/Objectives: First responders frequently encounter high-stress environments that challenge physiological resilience and autonomic regulation. Heart rate variability (HRV) complexity is a critical marker of adaptive capacity and stress regulation. This study assessed the impact of a wearable-based mindfulness intervention on HRV complexity among first responders using a smartwatch. Methods: A total of 87 first responders participated in a one-month wearable-based intervention. Participants wore Garmin Vivosmart 5 devices to continuously collect PPG data (photoplethysmogram), focusing on beat-to-beat intervals (BBIs). The intervention involved daily Ecological Momentary Assessments (EMAs) and individual randomization to either a mindfulness message, a prompt to access an audio …

Edge Co-Occurrence Regularization For Node Classification, Kadir Altunel

Theses

We propose a simple yet effective regularization technique for node classification on graphs that leverages edge-based label co-occurrence patterns. We first train an MLP on node features to produce class probability distributions, then compute a fixed penalty matrix from edge-based co-occurrence statistics of these predictions. This penalty matrix, which captures unlikely class combinations on connected nodes, is then used to regularize GNN training without further updates. We evaluate this approach across multiple homophilic datasets (Cora, CiteSeer, PubMed, ogbn-arxiv) and heterophilic benchmarks (Chameleon, Squirrel, Actor, Roman-Empire) using three GNN architectures: GCN, GraphSAGE, and H2GCN. Results show consistent improvements on homophilic graphs, …

Deep Learning Approaches For Ctenophore Identification And Tracking, Anagha Bharadwaj

Theses

Ctenophores are translucent marine organisms with nearly invisible tentacles and pose significant challenges due to their transparent morphology and ambiguous structural features. This research addresses the classification and tracking of these organisms and evaluates the performance of current computer vision models under sparse-data environments.

A dataset from the NJIT Life History Lab consisting of microscopic laboratory videos and photographs of different growth stages is used to train and assess a number of convolutional neural network designs, including VGG16, ResNet, BioCLIP2, YOLO, and DeepLabCut. Additionally, a web-based interface is developed to evaluate expert-labeled ground truth with the model's performance.

The findings …

Evaluation Of Medical Instrument Reliability For The Heath And Maddox Components Of The Accommodative-Vergence System, Jacob Chabuel

Theses

Binocular vision relies on the coordination of near response triad composed in part by the vergence and accommodative systems. Binocular dysfunctions linked to these systems impact the quality of life of those affected by complicating day-to-day tasks and leading to further health concerns. Clinical evaluations that diagnose dysfunctions and tailor therapies rely on subjective methods, creating a need for a reliable, quantitative, measurement tool. This is achieved using a haploscope, a tool that quantitatively measures and observes binocular vision to identify deficiencies within the eye. Modernization of a haploscope system, measurement of the Heath and Maddox components of the visual …

Polarimetric Terahertz Imaging For The Measurement Of Birefringence In Plastic, Rachel Cohen

Theses

Birefringence offers a promising way to observe stress concentration in materials such as glass and plastic, and thereby to identify weaknesses. Polarimetric imaging can be used to measure the birefringence of material, so long as the material is transparent to the light being used for the imaging. In this research, 2D Terahertz imaging was investigated as a means of measuring the birefringence of plastics that are opaque to visible light but transparent to THz radiation, for the eventual purpose of analyzing the residual stress present. In order to do so, two separate terahertz cameras were characterized for potential use in …

Retinomorphic Mid-Wave Infrared In-Sensor Processing Engine: Device-To-Architecture Co-Design, Hemalatha Nagaraju

Theses

Conventional frame-based CMOS image sensors acquire full-frame pixel data at discrete time intervals, resulting in substantial spatial redundancy and loss of temporal information between frames. The repeated conversion and transfer of redundant pixel data increases bandwidth and power consumption in machine vision systems. Retinomorphic sensing architectures address these limitations by enabling programmable, analog-domain processing directly at the sensor interface. A compact behavioral model of the PbSe device is developed in HSPICE based on calibrated TCAD simulation data to capture gate-controlled photocurrent modulation under varying illumination and gate bias conditions. Error analysis is performed to quantify the deviation between TCAD-generated photocurrent …

Investigation Of Environmental Influences On Multiple Sclerosis: A Study For Egypt’S Health, Noha Ezzaldin Alziny Ali

Theses and Dissertations

Background: Multiple sclerosis (MS) is a complex, chronic neuroinflammatory disease influenced by both genetic and environmental factors. While global research has identified potential environmental influences, most evidence comes from Western populations, creating a significant knowledge gap for regions like Egypt, which has witnessed a dramatic rise in MS prevalence over recent decades. This study hypothesized that Egyptian MS patients exhibit a distinct biological signature in their blood, characterized by an imbalance in essential and toxic trace elements (the metallome) and alterations in stress-response biomarkers associated with neuroaxonal injury and cellular stress. Objective: This study aimed to comprehensively profile and compare …

Rethinking Flow: The Paradox Of Renoprotection Without Increased Renal Blood Flow In Cardiopulmonary Bypass, Shiksha Mohan, Ronald A Shaju, Sharan Misra, Titiksha Sharma, Veeraj K Sirivolu, Abhinav Rajkumar, Anthony Rodas-Camacho, Aizah Zaidi, Dhruv Dhingra, Ilma Khan, Rishav Bhattacharya, Vishal Pancholy, Shivam Banerjee, Shreyo Ghosh, Shiyi Li, Kenneth K Liao, Carl P Walther, Nandan K Mondal

Faculty, Staff and Students Publications

No abstract provided.

Perinatal Mental Health Screening And Care Among Those With Pregnancy Complications, Alison N Goulding, Terri L Fletcher, Emily S Miller

Faculty, Staff and Students Publications

Perinatal mental health conditions are common and, without effective treatment, can contribute to adverse maternal and child outcomes. In the United States, mental health conditions are a leading cause of maternal morbidity and mortality, contributing to over 20% of pregnancy-related deaths. This expert review aims to assess current literature and provide recommendations regarding mental health care in high-risk patients who experience pregnancy complications. Individuals experiencing pregnancy complications are at increased risk for perinatal mental health conditions, including depression, anxiety, and post-traumatic stress disorder, as compared to those with uncomplicated pregnancies. Despite this increased disease burden, there is limited research on …

Pickleweed In The Disappearing Marsh: Population Genetics & Metal Accumulation In Salicornia Depressa, Alice Kaisla

Graduate Doctoral Dissertations

Salicornia is a genus of succulent halophytes found in salt marshes around the world. Salicornia species have a remarkably high tolerance for heavy metal pollution and have been shown to accumulate high concentrations of heavy metals in their tissue under experimental conditions. As a result, they are both a useful system for studying evolution in polluted coastlines and a potential candidate for use in phytoremediation. My research focuses on Salicornia depressa, known as pickleweed, a species commonly found in marshes along the heavily urbanized and industrialized New England coast. I investigate genetic diversity and population structure in S. depressa populations …

Streamlined Biomedical Image Processing Pipelines, Jiehyun Kim

Graduate Doctoral Dissertations

This dissertation focuses on advancing carotid artery analysis through a series of visualizations and deep learning tools for calcified plaque assessment and related biomedical imaging tasks. Accurate plaque evaluation is essential, but current workflows depend on slow, clinician-dependent manual review. To address these limitations, this work introduces the CACTAS framework, a set of tools and methods that enable fast and reliable plaque segmentation for clinicians.

The first study, the CACTAS-Tool, provides a web-based labeling tool that enables clinicians to label plaque directly in three dimensions through a streamlined one-click interface. This tool significantly reduces the effort required to generate high-quality …

Computer-Aided Development Of Novel Antioxidants, Rita Bernadett Vlocsko

Graduate Doctoral Dissertations

Physiological redox homeostasis is a fine balance between prooxidants and antioxidants that are integrated elements of several reduction-oxidation mechanisms at molecular, organellar, cellular and tissue levels. When this equilibrium is disrupted and prooxidants become dominant, the body relies on endogenous and exogenous antioxidants to counterbalance the dysregulation and ultimately prevent the progression of oxidative stress. Reactive species (reactive oxygen species, reactive nitrogen species, or reactive sulfur species) are significant contributors to prooxidant activity. Over the years, substantial knowledge has been accumulated regarding their origin and roles in disease development, leading to the discovery and development of antioxidants that effectively target …

Trends Of Pediatric Psychotropic Polypharmacy In Massachusetts Before And During The Covid-19 Pandemic, Gianna D'Ambrozio

Graduate Doctoral Dissertations

Youth in the U.S. and internationally are increasingly being diagnosed with depression and related psychiatric conditions (Murthy, 2021) many of whom are being subjected to non-evidence-based, or what has been termed irrational, psychotropic polypharmacy (Barnett & Concepcion Zayas, 2019). Psychotropic polypharmacy can be defined as “the use of 2 or more psychiatric medications in the same patient,” (Zito et al., 2021) though definitions can vary. Using data from the Center for Health Information Analysis’ Massachusetts All-Payer Claims Database, this study examined the sociodemographic factors associated with high rates of polypharmacy, a hypothesized increase in pediatric psychotropic polypharmacy rates in Massachusetts …

Adapting Population Genetics, Practice, And Policy For Plant Conservation In A Changing World, Cooper M. Kimball-Rhines

Graduate Doctoral Dissertations

Biodiversity conservation is an inherently interdisciplinary goal that requires effective collaboration among academics, ecosystem managers, policymakers, and other stakeholders. Codesigning research with these groups ensures experiments are useful and improves adoption of policy and practice recommendations while advancing our understanding of basic science. This dissertation explores the power of codesigned research in shaping plant conservation strategies using stakeholder engagement, causal inference, demographic modeling, and multi-omic sequencing techniques. In chapter 1 I discuss the history of New England ecosystems and the need for research-driven changes to plant conservation policy and practice in the face of global change. In chapter 2, I …

Static Data-Race Detection For Gpu Programs: Behavioral Types With Partial Completeness Guarantees, Zhen Rong Liew

Graduate Doctoral Dissertations

GPUs are essential to modern computing but notoriously difficult to program correctly. Static analysis tools can verify data-race freedom, but their over-approximations produce spurious reports of data races that do not occur, limiting their practical usefulness. This dissertation establishes when Memory Access Protocols (MAPs), a compositional abstraction modeling memory access behavior between synchronization barriers, can be simultaneously sound and complete. We first prove that MAP-based analysis is sound and complete for well-typed Jaminan programs---those without data-dependent array indexing. This result establishes the theoretical boundary: completeness is achievable when data-dependent control flow and indexing are absent. Jaminan extends MAPs with symbolic …

Talk To Me: Exploring The Sociocultural Ecology Of Home Language And Literacy Practices Of Families In India, Surbhi Puri

Graduate Doctoral Dissertations

Existing research highlights the role of home language and literacy environments (HLLE) in shaping early language and literacy development, yet few studies have examined the practices of multilingual families in India. While home environments offer rich learning opportunities, broader sociocultural and policy contexts influence how families support literacy and language development. Families’ insights into home language use, literacy routines, and cultural practices remain underexplored in early childhood education research.

The purpose of this qualitative multiple case study was to explore the HLLE of preschool-aged children in India and examine how families support early language and literacy development within multilingual home …

Small Molecule Antioxidants As Potential Therapeutics For Preeclampsia, Maxim Mastyugin

Graduate Doctoral Dissertations

The major goal of this work was to develop a therapeutic intervention against preeclampsia (PE). Preeclampsia affects up to 5-7% of all pregnancies and has no causative treatments. It is associated with oxidative stress caused by a prolonged ischemic state and increase in reactive oxygen species (ROS) in the placenta. The cardinal symptoms include high blood pressure, kidney dysfunction, and in severe cases, eclampsia. With no treatment for the underlying causes available, we offer small molecule antioxidants which may scavenge ROS in the placenta arising from the initiating event of PE, the oxidative stress. By reducing placental ROS, these antioxidants …

Xanthogranulomatous Osteomyelitis As A Bone Tumor Mimic: A Systematic Review Of Pre-Biopsy Diagnostic Clues And Management Decision Points, Ethan J. Sack, Max Deneroff, Austin Khau, Zubair Mohammed, Chadi Ellaham, Jared Nichols

Student Publications

Xanthogranulomatous osteomyelitis (XO) is a rare inflammatory form of osteomyelitis that can closely resemble a primary bone tumor or metastatic lesion at presentation. This systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and focused on pre-biopsy diagnostic clues and management decision points in published skeletal XO reports. PubMed, Embase, and Scopus were searched from January 2026 to May 2026, identifying 86 records. Eligible studies included human case reports and case series describing histologically confirmed skeletal XO or xanthogranulomatous inflammation involving bone; non-skeletal xanthogranulomatous disease, duplicate reports, review articles without extractable patient-level …