Digital Commons Network^™

Examining The Effect Of Exercise Intensity On Post-Exercise Hypotension In Middle-Aged Adults, Seth F. Mccarthy

Theses and Dissertations (Comprehensive)

Acute bouts of exercise have a transient lowering effect on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in the hours after termed post-exercise hypotension (PEH). While moderate-intensity continuous training (MICT) is effective in reducing BP acutely, little is known regarding the effects of higher intensity exercise. This study examined the effects of different exercise intensities on PEH. Six participants (females: 4; age: 48±9 y, Mean arterial pressure: 84±8 mmHg) had their BP measured before and both immediately post- (<2 h) and for 24 h following 4 experimental sessions: 1) 30 min MICT (65% V̇O_2max); 2) 20 min high-intensity interval training (HIIT; 10 x 1 min @ 90% HR_max with 1 …

Domain-Specific Self-Compassion In Individuals High Versus Low In Social Anxiety, Leah Brassard

Theses and Dissertations (Comprehensive)

Self-compassion involves showing kindness and understanding to the self during times of hardship. Individuals with social anxiety have been shown to exhibit lower levels of self-compassion than the general population. The present set of studies seeks to build support for a domain-specific conceptualization of self-compassion, as it relates to social anxiety. Study One (N=160) explored self-compassionate responding in three domains of stress from self-generated recollections in an online format. It was predicted that individuals high in levels of social anxiety would be more self-compassionate in scenarios involving non-social situations (i.e., burnout, physical illness) than in a socially evaluative …

Synthesis And Biophysical Analysis Of The Cell-Penetrating Peptide Penetratin And Its Aromatic Analogues, An Le

Theses and Dissertations (Comprehensive)

Cell-penetrating peptides (CPPs) interact with biological membranes, undergo cellular intake/uptake, and may act as potential drug delivery agents. Understanding the molecular interactions of these peptides with membranes contributes to gaining a better knowledge of their potential use in medical and pharmaceutical applications to improve human health. The current research focuses on understanding the mechanisms of a CPP in interaction with different model phospholipid membranes. The peptide penetratin (primary sequence: RQIKIWFQNRRMKWKK) is an example of a CPP that can interact with and pass through biological membranes. The current thesis provides spectroscopic and calorimetric evidence that penetratin associates with lipid membranes. Circular …

Can Zooplankton On The North American Great Plains ‘Keep Up’ With Climate-Driven Salinity Change?, Mariam Elmarsafy

Theses and Dissertations (Comprehensive)

The Great Plains of North America are projected to become more arid as the climate changes over the next century. Salinity levels for lakes in this region are linked to climate, suggesting that lakes will become more saline as the climate becomes drier. One group of organisms that might be affected by increased salinity levels are the zooplankton, aquatic invertebrates that transfer energy from primary producers to macroinvertebrates and fish. Little is known about the ability of zooplankton to adapt to long-term increases in lake salinity levels. For my thesis, I used resurrection ecology to examine how a common zooplankter, …

The Role Of Streptococci In Oral Periodontitis: Growth And Disruption Of Yellow Complex Bacteria, Megan Gordon

Theses and Dissertations (Comprehensive)

Periodontitis is described as the inflammation of the periodontium and affects millions of people worldwide. This disease is caused by biofilm growth of certain bacteria on the tooth surface, adjacent to the gum tissue in the oral cavity. There are currently treatments against severe periodontitis, such as oral surgery and use of broad-spectrum antibiotics, but they fail to target the specific bacteria associated with periodontitis. Socransky et al., (1998), identified the preponderance for specific organisms in distinct areas of the subgingival pockets to associate with different bacteria forming consortia and complexes. The yellow complex, containing facultatively anaerobic, Gram positive …

Chlorophyll Fluorescence Corrections From A Rapid-Profiling, Autonomous Wirewalker, Melanie Feen

Open Access Master's Theses

Stimulated chlorophyll fluorescence (ChlF) is a fairly simple measurement to collect, and is ubiquitous on most biogeochemical autonomous platforms. However, complex physiological phenomenon challenge the interpretation of the data. Nonphotochemical quenching (NPQ) markedly reduces the fluorescence during high light regimes, favoring dissipation of this energy as heat. This study evaluates previously developed NPQ correction methods, typically implemented on floats or gliders, for a fast profiling, autonomous, drifting Wirewalker deployed during the EXPORTS field campaign at Ocean Station Papa (OSP) in the Subpolar North Pacific Ocean. Through validating NPQ-corrected chlorophyll to absorption line height, which is not subject to the same …

Analysis Of Missing Data In Marine Dissolved Oxygen Time Series Using Dynamic Linear Models, Shajratul Alam

Open Access Master's Theses

The marine ecosystems cannot survive without dissolved oxygen (DO). Low oxygen events (hypoxia) in the ocean cause stress on the benthic community and, hampers their growth rate initiating mortality. To monitor the concentration of oxygen, different water quality monitoring sites have been established across the globe. The Narragansett Bay fixed-site water quality monitoring network (NBFWQMN) is a facility that regularly measures oxygen level as well as other important water parameters (temperature, salinity, pH level, and Chlorophyll) at different locations of Narragansett Bay (NB). Missing observation is a common phenomenon for this times-series dataset and, can occur for various reasons. In …

Applications To Collect And Analyze Or Destroy Energetics And Chemical Warfare Agents, Victoria Stubbs

Open Access Master's Theses

Terrorism is an ever-present threat in our society. In the last decade alone, terrorists killed an average of 21,000 people each year [1]. In 2018, there were 289 bombings in the US, and bomb threats increased by 32% since the year prior [2]. Before that, there was an average of 205 criminal bombings in the US between 2004 and 2005 [3]. All of this is not including the 2,996 lives lost when 4 planes struck the Pentagon, the Twin Towers, and a field in Pennsylvania, leaving long term physical and mental wounds on those who were affected by it [4]. …

Trophic Niche Overlap Of Atlantic Cod And Black Sea Bass In Relation To Warming Southern New England Waters, Nina Santos

Open Access Master's Theses

In southern New England (SNE), a new ecological interaction is occurring as temperate black sea bass abundance increases in the home range of the iconic Atlantic cod as a result of climate-induced ocean warming. In this study, we examined the diet and trophic dynamics of both SNE Atlantic cod and black sea bass using a multi-tracer approach of stomach content analysis as well as bulk and compound-specific amino acid isotope analyses. We reveal a highly selective diet (0.01-0.43 Levin’s index) with decapod crustaceans occurring in 82-89% of stomachs and making up 72-79% of the total wet weight for both species, …

Taxonomic Profiling Of Metagenomic Reads Using Deep Learning, Cecile Cres

Open Access Master's Theses

The field of metagenomics studies microbes from environmental samples in a process generating millions of short DNA sequences called reads. The final outcome is to discover the diversity as well as the function of complex microbial communities using computational tools. The general idea adopted by most taxonomic classifiers, which aim to assign taxonomic groups to individual reads, is to compare the target DNA sequences to a reference database and identify the taxon of the best match. This method has many disadvantages including the necessity for large computing resources in order to process large sequence databases. The current project aims to …

Remote Sensing Of Phytoplankton Size Classes On The Northeast U.S. Continental Shelf, Kyle J. Turner

Open Access Master's Theses

The size structure of phytoplankton communities influences important ecological and biogeochemical processes, including the transfer of energy through marine food webs. A variety of algorithms have been developed to estimate phytoplankton size classes (PSCs) from satellite ocean color data. However, many of these algorithms were developed for application to the open ocean, and their performance in more productive, optically complex continental shelf systems has not been fully evaluated. In this study, several existing PSC algorithms were applied in the Northeast U.S. continental shelf (NES) and assessed by comparison to in situ PSC estimates derived from a regional HPLC pigment data …

Training, Equipping, And Deploying Teenagers For Preaching With A Prophetic Emphasis At The Plantation Seventh-Day Adventist Church, Iosif Salajan

Doctor of Ministry Projects

Problem

Teenagers were not integrated in the preaching ministry of the Plantation Seventh-day Adventist Church. Their involvement in the worship service revealed challenges in publicly expressing their faith and spiritual experience. The absence of training, equipping, and deploying teenagers for preaching ministry contributed to their low retention and their lack of representation in the leadership of the church.

Method

Between August 2018 and May 2019, under the coordination of the researcher, preaching mentors offered teenage mentees from the Plantation Seventh-day Adventist Church a complete learning cycle called sermonic process. It started with producing the sermon, continued with practicing the sermon …

Investigating The Nightime Departures Of Glaucous-Winged Gulls (Larus Glaucescens) And The Role Of Social Facilitation, Devon Leigh Mcclain

Master's Theses

Daytime behaviors and occupancy patterns of Glaucous-winged Gulls (Larus glaucescens) have been described and can be mathematically predicted based on environmental factors. However, little is known about the nighttime behaviors of Glaucous-winged Gulls. I used trail cameras to study the daytime and nighttime colony occupancy patterns of Glaucous-winged Gulls on a breeding colony on Protection Island, Washington, USA. Early in the breeding season gulls desert the colony en masse during nighttime even after some gulls have initiated clutches. Using acoustic recording units to identify an acoustic cue that signals the onset of the coordinated nightly departures from the colony, I …

A Study Of Inactive Enzyme-Homologues: The Biochemical And Biological Function Of Ecm14 In Saccharomyces Cerevisiae, Robert Christian Mcdonald

Master's Theses

Like most major enzyme families, the M14 family of metallocarboxypeptidases (MCPs) contains several pseudoenzymes predicted to lack enzyme activity and with unknown molecular function. The genome of the yeast Saccharomyces cerevisiae encodes only one member of the M14 MCP family, a pseudoenzyme named Ecm14 proposed to function in the extracellular matrix. Ecm14 is found throughout ascomycete fungi, with a group of related pseudoenzymes found in basidiomycetes. Although the prodomain of Ecm14 can be cleaved in vivo and in vitro by endopeptidases, suggesting an activation mechanism, no activity has been detected using standard carboxypeptidase substrates.

In order to examine the function …

Ecological Mechanisms Explaining Interactions Within Plant–Hummingbird Networks: Morphological Matching Increases Towards Lower Latitudes, J Sonne, J Vizentin-Bugoni, Pk Maruyama, Ac Araujo, E Chávez-González, Ag Coelho, Pa Cotton, Oh Marín-Gómez, C Lara, Lr Lasprilla, Cg Machado, Ma Maglianesi, Ts Malucelli, Amm González, Gm Oliveira, Pe Oliveira, R Ortiz-Pulido, Ma Rocca, Lc Rodrigues, I Sazima, Bi Simmons, B Tinoco, Ig Varassin, Mf Vasconcelos, B O'Hara, M Schleuning, C Rahbek, M Sazima, B Dalsgaard

School of Biological and Marine Sciences

Interactions between species are influenced by different ecological mechanisms, such as morphological matching, phenological overlap and species abundances. How these mechanisms explain interaction frequencies across environmental gradients remains poorly understood. Consequently, we also know little about the mechanisms that drive the geographical patterns in network structure, such as complementary specialization and modularity. Here, we use data on morphologies, phenologies and abundances to explain interaction frequencies between hummingbirds and plants at a large geographical scale. For 24 quantitative networks sampled throughout the Americas, we found that the tendency of species to interact with morphologically matching partners contributed to specialized and modular …

An Overview Of Physical Risks In The Mt. Everest Region, Kimberley R. Miner, Paul A. Mayewski, Saraju K. Baidya, Kenneth Broad, Heather Clifford, Aurora Elmore, Ananta P. Gajurel, Bibek Giri, Sam Guilford, Mary Hubbard, Corey Jaskolski, Heather Koldewey, Wei Li, Tom Matthews, Imogen Napper, L. Baker Perry, Mariusz Potocki, John C. Priscu, Alex Tait, Richard Thompson, Subash Tuladhar

School of Biological and Marine Sciences

No abstract provided.

Microplastic Accumulation In Deep-Sea Sediments From The Rockall Trough, Winnie Courtene-Jones, Brian Quinn, Ciaran Ewins, Stefan F. Gary, Bhavani E. Narayanaswamy

School of Biological and Marine Sciences

Microplastics are widely dispersed through the marine environment. Few studies have assessed the long-term or historic prevalence of microplastics, yet acquiring such data can inform their distribution, transport and the environmental risks posed. To quantify the distribution and polymer types temporally, sediment cores were collected from >2000 m water depth in the Rockall Trough, North Atlantic Ocean. As hypothesized, a significant negative trend was observed in the frequency of microplastics with increasing sediment age, however there was an increase in polymer diversity. Microplastics were pervasive throughout the sediment analysed (10 cm depth), yet lead-210 (210Pb) activities were confined to the …

Occurrence And Assemblage Composition Of Intertidal Non-Native Species May Be Influenced By Shipping Patterns And Artificial Structures, Kathryn A. O'Shaughnessy, Stephen J. Hawkins, Anna L.E. Yunnie, Mick E. Hanley, Paul Lunt, Richard C. Thompson, Louise B. Firth

School of Biological and Marine Sciences

Habitat modification coupled with the spread of non-native species (NNS) are among the top threats to marine biodiversity globally. Species are known to be transported to new locations via international shipping and secondarily spread via regional vessels and artificial structures. Rapid Assessment Surveys (RAS) combining quantitative and semi-quantitative methods compared NNS richness and assemblage composition on intertidal natural rocky shores and artificial structures in harbours in different regions along the south coast of England. Quantitative data showed that artificial habitats supported higher richness than natural habitats, while semi-quantitative data found no difference in richness among habitat types. This result was …

Ebola And Emerging Infectious Diseases In Armed Conflict: Contemporary Challenges In Global Health Security Laws And Policies, Caroline Sell

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

No abstract provided.

The Limits Of Equality And Gender Discourses In Counter-Terrorism: The Case Of Women And Children In Syria And Iraq, Fionnuala Ní Aoláin

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

No abstract provided.

Testing Gene-Environment Interactions For Rare And/Or Common Variants In Sequencing Association Studies., Zihan Zhao, Jianjun Zhang, Qiuying Sha, Han Hao

Michigan Tech Publications, Part 1

The risk of many complex diseases is determined by a complex interplay of genetic and environmental factors. Advanced next generation sequencing technology makes identification of gene-environment (GE) interactions for both common and rare variants possible. However, most existing methods focus on testing the main effects of common and/or rare genetic variants. There are limited methods developed to test the effects of GE interactions for rare variants only or rare and common variants simultaneously. In this study, we develop novel approaches to test the effects of GE interactions of rare and/or common risk, and/or protective variants in sequencing association studies. We …

A Review Of Open Source Ventilators For Covid-19 And Future Pandemics., Joshua M. Pearce

Michigan Tech Publications, Part 1

Coronavirus Disease 2019 (COVID-19) threatens to overwhelm our medical infrastructure at the regional level causing spikes in mortality rates because of shortages of critical equipment, like ventilators. Fortunately, with the recent development and widespread deployment of small-scale manufacturing technologies like RepRap-class 3-D printers and open source microcontrollers, mass distributed manufacturing of ventilators has the potential to overcome medical supply shortages. In this study, after providing a background on ventilators, the academic literature is reviewed to find the existing and already openly-published, vetted designs for ventilators systems. These articles are analyzed to determine if the designs are open source both in …

Nonheme Iron–Thiolate Complexes As Structural Models Of Sulfoxide Synthase Active Sites, Danushka M. Ekanayake, Anne A. Fischer, Maya E. Elwood, Alexandra M. Guzek, Sergey V. Lindeman, Cordina V. Popescu, Adam T. Fiedler

Chemistry Faculty Research and Publications

Two mononuclear iron(II)–thiolate complexes have been prepared that represent structural models of the nonheme iron enzymes EgtB and OvoA, which catalyze the O₂-dependent formation of carbon–sulfur bonds in the biosynthesis of thiohistidine compounds. The series of Fe(II) complexes reported here feature tripodal N₄ chelates (L^A and L^B) that contain both pyridyl and imidazolyl donors (L^A = (1H-imidazol-4-yl)-N,N-bis((pyridin-2-yl)methyl)methanamine; L^B = N,N-bis((1-methylimidazol-2-yl)methyl)-2-pyridylmethylamine). Further coordination with monodentate aromatic or aliphatic thiolate ligands yielded the five-coordinate, high-spin Fe(II) complexes [Fe^II(L^A)(SMes)]BPh …

Route Exploration And Synthesis Of The Reported Pyridone-Based Pdi Inhibitor Stk076545, Eric Greve, Sergey V. Lindeman, Christina Scartelli, Lin Lin, Robert Flaumenhaft, Chris Dockendorff

Chemistry Faculty Research and Publications

The enzyme protein disulfide isomerase (PDI) is essential for the correct folding of proteins and the activation of certain cell surface receptors, and is a promising target for the treatment of cancer and thrombotic conditions. A previous high-throughput screen identified the commercial compound STK076545 as a promising PDI inhibitor. To confirm its activity and support further biological studies, a resynthesis was pursued of the reported β-keto-amide with an N-alkylated pyridone at the α-position. Numerous conventional approaches were complicated by undesired fragmentations or rearrangements. However, a successful 5-step synthetic route was achieved using an aldol reaction with an α-pyridone allyl …

Like Sand From The Pyramids: Using Rare Books And Manuscripts To Facilitate Object-Based Learning In The Law School Classroom, Melissa M. Hyland

Faculty Publications

This article advocates adding object-based learning, utilizing rare legal books and manuscripts, to the legal education toolbox. Object-based learning is an educational methodology that explains the many learning benefits resulting from student engagement with tangible objects of material culture. Studies into the use of this methodology with undergraduate and graduate students are rather new, but research indicates that object-based learning produces measurable positive results across the curriculum.

Part I of this article provides an overview of object-based learning, with subsections addressing its relationship to active learning, its incorporation of multiple learning styles, and its ability to encourage affective learning. Part …

Dynamic Prostatic And Laser-Ablated Lesion Volume Change After Transperineal Laser Ablation In Canine: Preliminary Observation And Its Clinical Significance., Rui-Qing Liu, Ji-Bin Liu, Shao-Bo Duan, Si-Guo Cheng, Zhi-Yang Chang, Hui-Cun Cao, Guang-Shao Cao, Ya-Qiong Li, Na Li, Lian-Zhong Zhang

Department of Radiology Faculty Papers

AIM: The purpose of this study is to observe the volume change of prostate and laser-ablated lesions in the canine and to explore the mechanism and clinical significance through histopathology.

MATERIALS AND METHODS: Transperineal laser ablation (TPLA) was performed under the guidance of transrectal ultrasound (TRUS) in eight canines. Two canines were sacrificed 1 day and 1 week after TPLA, respectively. The remaining six canines were sacrificed after finishing transrectal contrast-enhanced ultrasound (TR-CEUS) at three phases.

RESULTS: The prostatic volumes immediately following TPLA and 1 week later were larger than before TPLA (20.1 ± 3.9 vs 17.1 ± 3.8 ml; …

Can Farmers And Bats Co-Exist? Farmer Attitudes, Knowledge, And Experiences With Bats In Belize, Hannah G. Shapiro, Adam S. Willcox, Mallory Tate, Emma V. Willcox

Human–Wildlife Interactions

Bats (Chiroptera) are often viewed negatively by the public. Negative public perceptions of bats may hinder efforts to conserve declining populations. In Belize, the presence of vampire bats (Desmodus rotundus and Diphylla ecaudata) exacerbates the potential for conflicts with humans because of the increased rabies transmission risks. To mitigate these risks, the Belize government provides farmers with assistance to trap and remove vampire bats. In June 2018, we surveyed farmers (n = 44) in and adjacent to the Vaca Forest Reserve in Belize to learn more about their attitudes, knowledge, and experiences with bats. This information may …

Evaluation Of The Impacts Of Radio-Marking Devices On Feral Horses And Burros In A Captive Setting, Kathryn A. Schoenecker, Sarah R. B. King, Gail H. Collins

Human–Wildlife Interactions

Radio-collars and other radio-marking devices have been invaluable tools for wildlife managers for >40 years. These marking devices have improved our understanding of wildlife spatial ecology and demographic parameters and provided new data facilitating model development for species conservation and management. Although these tools have been used on virtually all North American ungulates, their deployment on feral horses (Equus ferus caballus) or burros (E. asinus) has been limited. To determine if radio-collars and radio-tags could be safely deployed on feral equids, we conducted a 1-year observational study in 2015 to investigate fit and wear of radio-collars …

Post-Tonal Postcards: Communicating Analysis And Reflection Through Prose Writing, Angela Ripley

Journal of Music Theory Pedagogy

Postcard assignments provide a concise alternative to the traditional analysis paper. In this article, I outline a series of four postcard assignments developed for an undergraduate post-tonal theory course, discuss connections to the Scholarship of Teaching and Learning (particularly to Self-Determination Theory), and examine student responses and pedagogical benefits. Synthesizing analysis and reflection, each postcard includes a 300- to 500-word essay as its message and a single page of annotated musical examples as its picture. Students analyze complete compositions through the lenses of specific themes; for example, students discuss pentatonic collections and pitch centricity in Debussy’s “La fille aux cheveux …

Age-Related Changes In Speech And Voice: Spectral And Cepstral Measures, Christopher Dromey, Sammi Taylor, Shawn L. Nissen, Kristine Tanner, Dennis Eggett, Kim Corbin-Lewis

Faculty Publications

Purpose

This study examined differences in selected acoustic measures of speech and voice according to age and sex and across families.

Method

Participants included 169 individuals, 79 men and 90 women, from 18 families, ranging in age from 17 to 87 years. Participants reported no history of articulation disorders, stroke or active neurologic disease, or severe-to-profound hearing loss. They read aloud two passages to facilitate examination of the following speech and voice acoustic parameters: fricative spectral moments (center of gravity, standard deviation, skewness, and kurtosis), the proportion of time spent speaking, mean speaking fundamental frequency, semitone standard deviation (STSD), and …