Digital Commons Network^™

Quantifying Whole Pancreas Area In Type 1 Diabetes Susceptible Rodent Model, Ian Ross, Evann Fowler

Summer Community of Scholars Posters (RCEU and HCR Combined Programs)

No abstract provided.

Gita And Betty: An Internationalist Love Story, Elisabeth Armstrong

Study of Women, Gender, & Sexuality: Faculty Books

"Gita and Betty: An Internationalist Love Story" is part of Faith in the Masses: a collection of 12 essays by historians and activist-scholars on various aspects of the 100-year history of the CPUSA. The essays in this book demonstrate the Communist Party, USA's century long commitment to equality, workers' rights, peace, and socialism. They highlight the struggle for African American equality, Black liberation, and women's rights, and place athletic, cultural, and literary activities well within the scope of CPUSA work. This book asserts that the CPUSA played a leading role in the social and economic justice struggles of the …

Syllabus Language, Teaching Style, And Instructor Self-Perception: Toward Congruence, Christopher Richmann, Courtney Kurinec, Matthew Millsap

International Journal for the Scholarship of Teaching & Learning

As with all language, the words of a syllabus carry emotional associations. Previous literature has not objective-ly measured the emotional associations of syllabus language or explored the relationship between instructors’ teaching style and the emotional associations of syllabus language. Using the Pleasure-Arousal-Dominance (PAD) framework, this article reports baseline measurements for syllabus language, investigates the relationship be-tween Grasha’s teaching styles and instructors’ self-perceived emotional associations with teaching, and compares instructors’ self-perceptions with the emotional associations of their syllabus language. Moderate correlations between teaching PAD scores and Grasha’s teaching style inventory suggest the emotion that may connect with concrete teaching attitudes and …

Comparing Mastery-Based Testing With Traditional Testing In Calculus Ii, Amanda Harsy, Alyssa Hoofnagle

International Journal for the Scholarship of Teaching & Learning

The authors present the results of quantitative data and student feedback from a two-year study of the effects of a new assessment model called “mastery-based testing.” In mastery-based testing, students are given problems in which they can only receive full credit for the problem after they demonstrate mastery of the objective being assessed. This method strives to increase complete understanding of concepts through a growth-mindset approach to learning in addition to helping alleviate math anxiety. In this study, we compare the impact of mastery-based testing with traditional testing in six Calculus II classes. The data sources for the project included …

Virginia Dental Journal (Vol. 97, No. 3, 2020)

Virginia Dental Journal

No abstract provided.

Attachment Dynamics As A Precursor For Sexual Risk-Taking Behaviors In Emerging Adulthood (18-25 Years Old), Eimileanne Delaney

Graduate Research Theses & Dissertations

This study explored the relationship between attachment and sexual risk-taking behaviors in emerging adulthood. Understanding and identifying the variables that influence sexual risk behaviors are important to the design and implementation of therapeutic interventions and psychoeducation. It was hypothesized that there is a statistically significant relationship between attachment and increased levels of sexual risk-taking behaviors in emerging adults. To investigate the research hypothesis, this study used a quantitative correlational design to examine the relationship(s) between the variables. The participants completed three online questionnaires: a demographic questionnaire, the Sexual Risk Survey (SRS), and the Relationship Questionnaire (RQ). Results suggested that there …

Tunable Refractive Index Through Spatially Modified Nanoparticle Films For Long-Range Spr Biosensing Applications, Stephen Joshua Binderup

Graduate Research Theses & Dissertations

Despite optics and refraction being among the oldest scientific principles, material limitations have prevented scientists from taking full advantage of the potential this technology holds. Indeed, films with designer optical properties have potential for use in exotic cloaking architectures, advanced waveguides, and precise optical biosensors. This thesis focuses on the fabrication methodology for making thin films with refractive index tuned to a desired value through self-assembly of amorphous nanoparticle films made of organosilicate materials. The inclusion of a slowly evaporating polymer phase along with the organosilicate nanoparticles results in nanopores formed within the film, which effectively reduce the film’s refractive …

Mobile Health Technologies May Be Acceptable Tools For Providing Social Support To Tuberculosis Patients In Rural Uganda: A Parallel Mixed-Method Study, Angella Musiimenta, Wilson Tumuhimbise, Esther Atukunda, Aaron T. Mugaba, Conrad Muzoora, Mari Armstrong-Hough, David Bangsberg, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background. Social support has been shown to mitigate social barriers to medication adherence and improve tuberculosis (TB) treatment success rates. The use of mobile technology to activate social support systems among TB patients, however, has not been well explored. Moreover, studies that tie supportive SMS (Short Message Service) texts to electronic monitoring of TB medication adherence are lacking.

Objective. To explore TB patients’ current access to social support and perceptions of utilizing real-time adherence monitoring interventions to support medication adherence. Methods. We purposively selected TB patients who owned phones, had been taking TB medications for ≥1 month, were receiving their …

Super Learner Analysis Of Real-Time Electronically Monitored Adherence To Antiretroviral Therapy Under Constrained Optimization And Comparison To Non-Differentiated Care Approaches For Persons Living With Hiv In Rural Uganda, Alejandra E. Benitez, Nicholas Musinguzi, David Bangsberg, Mwebesa B. Bwana, Conrad Muzoora, Peter Hunt, Jeffrey N. Martin, Jessica E. Haberer, Maya L. Petersen

OHSU-PSU School of Public Health Faculty Publications and Presentations

Introduction

Real‐time electronic adherence monitoring (EAM) systems could inform on‐going risk assessment for HIV viraemia and be used to personalize viral load testing schedules. We evaluated the potential of real‐time EAM (transferred via cellular signal) and standard EAM (downloaded via USB cable) in rural Uganda to inform individually differentiated viral load testing strategies by applying machine learning approaches.

Methods

We evaluated an observational cohort of persons living with HIV and treated with antiretroviral therapy (ART) who were monitored longitudinally with standard EAM from 2005 to 2011 and real‐time EAM from 2011 to 2015. Super learner, an ensemble machine learning method, …

Validation Of Microrna Biomarkers For Alzheimer’S Disease In Human Cerebrospinal Fluid, Jack T. Wiedrick, Jay I. Phillips, Theresa A. Lusardi, Trevor J. Mcfarland, Babbet Lind, Ursula K. Sandau, Christina A. Harrington, Jodi A. Lapidusa, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

We previously discovered microRNAs (miRNAs) in cerebrospinal fluid (CSF) that differentiate Alzheimer’s disease (AD) patients from Controls. Here we examined the performance of 37 candidate AD miRNA biomarkers in a new and independent cohort of CSF from 47 AD patients and 71 Controls on custom TaqMan arrays. We employed a consensus ranking approach to provide an overall priority score for each miRNA, then used multimarker models to assess the relative contributions of the top-ranking miRNAs to differentiate AD from Controls. We assessed classification performance of the top-ranking miRNAs when combined with apolipoprotein E4 (APOE4) genotype status or CSF amyloid-β42 (Aβ42):total …

Screening For Unhealthy Drug Use: Updated Evidence Report And Systematic Review For The Us Preventive Services Task Force, Carrie D. Patnode, Leslie A. Perdue, Megan Rushkin, Tracy Dana, Ian Blazina, Christina Bougatsos, Sara Grusing, Elizabeth A. O'Connor, Rongwei Fu, Roger Chou

OHSU-PSU School of Public Health Faculty Publications and Presentations

IMPORTANCE

Illicit drug use is among the most common causes of preventable morbidity and mortality in the US.

OBJECTIVE

To systematically review the literature on screening and interventions for drug use to inform the US Preventive Services Task Force.

DATA SOURCES MEDLINE, PubMed, PsycINFO, Embase, and Cochrane Central Register of Controlled Trials through September 18, 2018; literature surveillance through September 21, 2019. STUDY SELECTION Test accuracy studies to detect drug misuse and randomized clinical trials of screening and interventions to reduce drug use. DATA EXTRACTION AND SYNTHESIS Critical appraisal and data abstraction by 2 reviewers and random-effects meta-analyses. MAIN OUTCOMES …

A Model For Recommending Custody Of Minors Based On Neutrosophic Cognitive Map, Mesías Elías Machado Maliza, Janneth Ximena Iglesias Lola, Ximena Cangas Oña, Salah Hasan Saleh Al-Subhi

Neutrosophic Sets and Systems

No abstract provided.

Global Risks Of Intensive Animal Farming And The Wildlife Trade, Deborah Cao

Animal Sentience

This commentary discusses two issues highlighted by Wiebers & Feigin in the context of the current and future global health crisis: the wildlife trade and factory farming. Both are instances of globalized animal cruelty – in China as well as worldwide -- that require global solutions for the well-being of both humans and nonhumans.

Childhood Abuse And Early Menarche Among Peruvian Women, Yasmin V. Barrios, Sixto E. Sanchez, Christina Nicolaidis, Pedro Garcia, Bizu Gelaye, Qiuyue Zhong, Michelle A. Williams

School of Social Work Faculty Publications and Presentations

Purpose

Childhood abuse has been associated with age of menarche in some studies, but not all, and few have assessed the independent associations of sexual and physical abuse with early menarche. We examined the association between childhood abuse and early menarche among pregnant women in Lima, Peru.

Methods

Multinomial logistic regression procedures were used to estimate odds ratios (OR) and 95% confidence intervals (CIs) for early menarche (≤11 years) in relation to any physical or sexual childhood abuse, physical abuse only, sexual abuse only, and both physical and sexual abuse in a cohort of 1,499 pregnant (first trimester) women.

Results …

Cultural Humility In Community Practice: Reflections From The Neighborhood Story Project, Amie Thurber

School of Social Work Faculty Publications and Presentations

Although cultural humility is frequently emphasized in social work education as a lifelong commitment to reflection and action, there are few examples of what this looks like in practice—particularly outside the scope of clinical health settings. This paper situates the need for practitioner reflections on cultural humility and offers an autoethnographic case study of efforts to cultivate cultural humility in myself and among participants in a neighborhood-based action research project. I consider cultural humility from three relational positions: holding oneself accountable, creating conditions for cultural humility within groups, and acknowledging how group members co-create conditions for cultural humility.

Integration Of Steam With Allyl-Isothiocyanate For Soil Disinfestation, Dong Sub Kim, Mark Hoffmann, Steven Kim, Bertha A. Scholler, Steven A. Fennimore

Mathematics and Statistics Faculty Publications and Presentations

Steam has long been used to disinfest greenhouse soils. However, there is increasing interest in expanding the use of steam for in-field soil disinfestation as an alternative to chemical fumigants. Previous studies demonstrated that allyl-isothiocyanate (AITC) reduced viability of weed seeds and plant pathogen propagules, but AITC has a low vapor pressure and is relatively immobile in soil. Heat has been used in the past to enhance the mobility of soil fumigants such as methyl bromide (i.e., “hot gassing”). The effect of steam heat on the mobility of AITC is unknown. The objective of this study was to investigate the …

Community Violence Exposure Among Ethnic Minority Youth: Understanding The Predictive Roles Of Depressive Symptoms And Risky Behavior In A Community Sample, Amanda Nicole Burnside

Dissertations

Ethnic-minority youth residing in urban communities are disproportionately impacted by community violence exposure (ECV), and despite decades of research, rates of ECV in youth continue to increase. Further, person-based analyses have demonstrated variability in rates of ECV, even among youth who share similar risky demographic factors and it is important to examine the utility of psychological factors as predictors of ECV. Drawing from public health frameworks and the reciprocal-stress model, the current study seeks to better understand the longitudinal relationship between various components of depressive symptoms (depressed affect, somatic symptoms, depressive cognitions, suicidal thoughts and behaviors) in the prediction of …

Suffocated Cd8 T Cells In The Hypoxic Tumor Microenvironment, Lourdes Beatriz Plaza Rojas

Dissertations

Hypoxia is a common feature of solid tumors that plays an important role in angiogenesis, malignant progression and metastatic development. However, its impact on T cell anti-tumor responses is less known. We determined that CD8 tumor infiltrating lymphocytes (TILs) tend to localize to non-hypoxic tumor areas, suggesting a susceptibility to tumor-associated hypoxia. This led us to further study the effects of hypoxia in vitro by culturing spleen-derived mouse T cells in a humidified chamber at 0.5% O2, 5% CO2 and 37 °C. We found that T cell proliferation and effector function are reduced by hypoxia, severely affecting inflammatory cytokine production. …

Plant-Pollinator Associations In An Eastern Serpentine Savannah And The Effects Of Overbrowsing, Allyson Richins

Theses and Dissertations

Chapter 1: Native plant response to deer overbrowsing in a serpentine savannah

Plants are particularly vulnerable to physical disturbance in low productivity areas, due to a high cost of replacing lost plant tissue. In the eastern United States, serpentine grasslands are fragmented ecosystems with high concentrations of rare endemic plant species, low concentrations of soil nutrients, and uncontrolled deer overpopulation. This study assessed functional responses of native angiosperms in a rare eastern serpentine savannah to selective deer browsing. Plant count, flower count, floral area, vegetative area, and plant height of 10 serpentine plant species were compared inside and outside of …

Structural Basis For The Stereoselective Epoxidation Reaction In Polyether Natural Product Biosynthesis, Qian Wang

Open Access Theses & Dissertations

Polycyclic polyether natural products have received much attention due to their diverse biological activities, ranging from extreme toxicity to therapeutic properties, including antimicrobial, antifungal, and anticancer activities. They are featured by multiple cyclic ether groups that vary in the number, size, and arrangement. Ionophore polyethers contain multiple tetrahydrofuran and tetrahydropyran rings connected by either spiroketal systems or carbon-carbon single bonds. Over the past 40 years, significant progress has been made in deciphering polyether biosynThesis pathways. Remarkably, all members of the polycyclic polyether family are thought to be generated via a common biosynthetic scheme. In 1983, Cane, Celmer, and Westly proposed …

Additive Manufacturing Of Engineered Material Systems For Energy Applications, Luis Angel Chavez

Open Access Theses & Dissertations

Despite increasing efforts to use renewable electricity generation techniques in the last couple of decades, the world is still heavily reliant on traditional power generation techniques. This creates the need to make such systems cheaper and less pollutant through improvements to their efficiency. Increasing the efficiency and reliability of energy conversion systems, specially those based on combustion processes has been of interest for many years. However, material limitations have brought these systems to a stagnant condition.

A novel approach to help increase the efficiency of such systems is to closely monitor their operating conditions and therefore be able to increase …

Synthesis Of Nanotemplated, Glucose-Derived Adsorbents For The Removal Of Organic And Inorganic Pollutants From Water, Luis Alfonso Barrera

Open Access Theses & Dissertations

With an ever-present rise in population, along with an increase in industrial and manufacturing plants, contamination of potable water has become a global concern. While water treatment facilities exist which can help with the purification of water from bacterial and organic contaminants, these facilities are expensive to set in place and maintain. Therefore, in impoverished areas, point of use (POU) purification systems are often preferred, such as filters made from activated carbon. These filters are inexpensive and relatively easy to install and use. However, while activated carbons generally display excellent adsorption capabilities towards organic contaminants, their adsorption towards inorganic pollutants …

Some Fermi-Lowdin Orbital Self-Interaction Correction Studies On Atomic Systems, Christopher Alexis Ibarra

Open Access Theses & Dissertations

Density Function Theory (DFT) is a popular quantum chemistry calculation method with many appeals but also deficiencies. Many modification and additions to the method have been made over the years, such as self-interaction corrections and new density functional approximations. We review here the theoretical background needed for a basic understanding of quantum chemistry calculations. In addition, we present the quantum chemistry calculation method used in this paper called Fermi-Lowdin Self-Interaction Correction (FLOSIC), including the base code it was implemented on, the Naval Research Laboratory Molecular Orbital Library (NRLMOL) Code, and the resulting modified code simply called FLOSIC. Furthermore, we explore …

Reconciling Carbon Flux Discrepancies In A Desert Environment: Characterizing Influences Of Soil Processes Using Automated Co2 Flux Chambers, Alejandro Lara

Open Access Theses & Dissertations

Dryland ecosystems play a fundamental role in controlling the balance of carbon on a global scale. These ecosystems dominate the inter-annual variability of carbon uptake by terrestrial ecosystems, and this is driven by temperature and precipitation patterns. Despite this global importance, there are some important discrepancies that have been reported between CO2 fluxes measured with differing techniques, particularly between eddy covariance tower measurements of net ecosystem exchange (NEE) of carbon (C) versus on-the-ground methods such as chambers and biomass surveys. The discrepancy is a consequence of instrumentation and measurement technique differences; yet, its biological origins remain unknown. The goal of …

Race, Gender And Mediated Representations In The Farah Strike, Matthew Desiderio Minnich

Open Access Theses & Dissertations

May 1972, 4,000 garment workers at Farah Manufacturing Company in El Paso went out on strike for the right to be represented by a union. The strike against Farah was the first major social movement in the El Paso area in modern times. Over 80% of the striking workers were Latina. The female employees at Farah were at the forefront of the Chicana feminist movement. The labor battle at Farah proves the organic link between Chicana feminism and class struggle. The Farah strike caused a new family dynamic to rise from the ashes of the traditional Mexican household. Using Burke's …

Using Computational Fluid Dynamics And Machine Learning To Predict Sled Profile During High Speed Water Braking At Holloman High Speed Test Track, Jose A. Terrazas

Open Access Theses & Dissertations

Accurate prediction of a rocket sled test profile and water braking phenomena has potential to result in radical changes in designs of specific sleds and provide greater confidence of braking mechanism and recovery of critical infrastructures. Understanding the water's behavior with the sled is critical to predicting how the water could damage the sled and affect recoverability of the sled and determine success of the missions. Traditionally, sled design for the test missions had been guided by empirical/hand calculations to estimate the forces on various components. The calculations involved various approximations to arrive at the force balance law and predict …

A Role For Mek3 In The Oncogenesis Of Acute Lymphocytic Leukemia: Inactivation Of Mapk P38 Promotes Cell Proliferation Through Enhanced Degradation Of Mutant Mek3, Yoshira Marie Ayala-Marin

Open Access Theses & Dissertations

In the United States, pediatric leukemia has the second-highest cancer mortality rate in Hispanic children, especially Acute Lymphocytic Leukemia (ALL). While treatment of ALL has improved overall the five-year survival rate of ~90 %, not everyone has benefited. Twenty percent of them will experience relapse, and from these, 30 - 50 % will die. Unfortunately, the cause behind these dreadful statistics is poorly understood due to the complex etiology of this disease. Thereby, it is essential to identify potential oncogenic proteins that promote ALL so that new strategies can be developed to diagnose and treat this cancer. Whole Exome Sequencing …

Identification Of Interkingdom Interactions Of Cryptococcus Neoformans In Pigeon Excreta Using Next Generation Sequencing, Marlynn Cadena

Open Access Theses & Dissertations

Cryptococcus neoformans is an encapsulated fungus with worldwide distribution and associated with pigeon excreta. C. neoformans causes pulmonary cryptococcosis in immunocompromised populations, which results in high mortality. C. neoformans main virulence factor is its polysaccharide capsule that confers the fungus with the ability to form biofilms. Interkingdom interactions can have a positive, neutral or negative effect on C. neoformans in relation to its virulence and/or pathogenicity. C. neoformans survival within polymicrobial and other challenging communities has been shown to affect the evolution of its virulence factors. For example, the size of C. neoformans polysaccharide capsule is modulated during interactions with …

Integration Of 3d Structural And Sequence Features To Predict Gpcr Ligand Binding, Kwabena Owusu Dankwah

Open Access Theses & Dissertations

G protein-coupled receptors (GPCRs) are the largest class of cell-surface receptor proteins with important functions in signal transduction and often serve as therapeutic drug targets. With the rapidly growing public data on three dimensional (3D) structures of GPCRs and GPCR-ligand interactions, computational prediction of GPCR ligand binding becomes a convincing option to high throughput screening and other experimental approaches during the beginning phases of ligand discovery. Such predictions are cost-efficient and can be important aides for planning wet lab experiments to help elucidate signaling pathways and expedite drug discovery. There are existing computational tools for GPCR ligand binding prediction using …

The Study Of Non-Permanent Tattoo Ink Using Nano Silver Compounds And Untact 3d Printing Technology, Jisu Lee

Open Access Theses & Dissertations

Due to a recent epidemic of COVID 19, the possibility of 3D tattoo printing technology using the Internet of Things (IoT) control system developed in a non-face-to-face contact process was identified. A non-surgical tattoo process and hygiene safety differentiated with silver tattoo ink was used to solve the health problems arising from the surgical tattoo process and to identify 3D tattoo printing techniques through a non-personal contact concept. During the tattoo processing, the image selected by the customer is sent to a designated printer via an IoT control system in a separate location. A piston-type extruder (PTE) printing technique was …