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Optimization Of Dapoxyl Aptamer For Label-Free Bioanalysis, Jack E. Mordeson, Ryan P. Connelly, Pedro F. Madalozzo, Yulia Gerasimova

Digital Repository: Showcase of Undergraduate Research Excellence

No abstract provided.

Synthesis Of Guanidines From Thioureas Using Photocatalyst, Trin Sae-Tan

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this study, a photo catalytic guanylation is investigated using Ru(bpy)3Cl2 as a photocatalyst under visible light irradiation. The reaction can be performed in green solvent such as ethanol and water and non-toxic K2CO3 base using 1-5% of Ru(bpy)3Cl2 under 19W white LED irradiation. Under optimized condition, this method can be applied for guanylation of various thioureas carrying a variety of functional groups with morpholine. Moreover, the amine scope includes primary and secondary amine carrying various functional groups. As the result, more than twenty examples of guanidine products can be produced in fair to excellent yields. Moreover, the reaction can …

Do Patients Judge Success Of Treatment And Patient Acceptable Symptom State Based On Current Self-Reported Health Status?, Ryan Jacobson, Daniel Kang, Jeff Houck

Faculty Publications - College of Physical Therapy

Background: Value-based care models call for better interpretation of patient-reported outcomes. Patients may reference health status differently when appraising if an intervention was successful versus if their current state is acceptable. The purpose of this study was to determine the association between success of treatment (SOT), patient acceptable symptom state (PASS), and PROMIS measure T-scores, following a single primary care physical therapy encounter.

Methods: Cross-sectional study. Ninety-two patients with musculoskeletal complaints were administered standard SOT and PASS questions, and PROMIS Physical Function, Pain Interference, and Self-Efficacy for Managing Symptoms measures. Association of PASS and SOT was determined using rank biserial …

Can Patient-Reported Outcomes Measurement Information System® (Promis) Measures Accurately Enhance Understanding Of Acceptable Symptoms And Functioning In Primary Care?, Ryan Jacobson, Daniel Kang, Jeff Houck

Faculty Publications - College of Physical Therapy

Background: Value-based healthcare models will require prioritization of the patient’s voice in their own care toward better outcomes. The Patient-Reported Outcomes Measurement Information System® (PROMIS) gives patients a voice and leads providers to actionable treatments across a broad range of diagnoses. However, better interpretation of PROMIS measures is needed. The purpose of this study was to evaluate the accuracy of PROMIS Physical Function (PF), Self-Efficacy for Managing Symptoms (SE), Pain Interference (PI), Fatigue, and Depression measures to discriminate patient acceptable symptom state (PASS) in primary care, determining if that accuracy is stable over time and/or retained when PROMIS score thresholds …

Survival Of Enterococcus FaeciumIn Turkey Litter Under Different Temperature And Moisture Combinations, Steven G. Mcbride, Benjamin Holland, Pradeep Vasudevan, Joanna B. Mott

Virginia Journal of Science

Untreated poultry litter introduces a substantial load of fecal pathogens to the environment, impacting agriculture, public health and ecosystem function. There is substantial evidence that temperature and moisture are the primary drivers of fecal bacteria survival across ecosystems. However, both temperature and moisture effects have been shown to be modulated by the matrix in which the fecal bacteria are living. This context dependence highlights the importance of understanding fecal bacteria survival in a variety of matrices in order to implement effective waste management plans. In this study, we determined the survival patterns of Enterococcus faecium in post-use turkey litter under …

Patient Mental Attitude: A Systematic Review, Arni I. Djais, Heri Siswanto

Journal of Dentomaxillofacial Science

No abstract provided.

Bonding Over Bondage: Slavery, Racial Complexities And Commonalities In New Orleans, 1803-1819, Andrew Ruben Rodriguez

CGU Theses & Dissertations

Different events in the nineteenth century have transformed America’s sociopolitical,

physical and cultural landscape and contributed to the formation of an American identity based on political liberty, a concept that revolved around the notion of freedom. The concept of slavery, which was opposite of liberty, would be a powerful force throughout American history. As Reverend John A. Ryan explained, liberty “consists mainly of the right to engage in an occupation, to make contracts, and to acquire property. From the beginning of our history as a nation, the constitutions of the various states protected this sphere of liberty for members of …

The Effects Of Myriad And Mayo On Molecular-Test Development In The United States And Europe: Interviews From The Frontline, Johnathon Liddicoat, Kathleen Liddell, Mateo Aboy

Vanderbilt Journal of Entertainment & Technology Law

US Supreme Court decisions in Mayo Collaborative Services v. Prometheus Laboratories and Association for Molecular Pathology v. Myriad Genetics Inc. caused US and European law on what is patentable subject matter to diverge significantly. Both cases related to molecular tests and changed decades of patent practice. Whether the decisions adversely affect the development of molecular tests in the United States and Europe has been a matter of much speculation but limited empirical investigation. This interview-based study has three main findings. First, Myriad and Mayo have negatively affected the development of some molecular tests. Notably, half of the US university technology-transfer …

Gmo Corn, Mexico, And Coloniality, Ernesto Hernandez-Lopez

Vanderbilt Journal of Entertainment & Technology Law

Genetically modified ("GMO") corn germinates legal controversies in Mexico. Since 2013, Mexican courts have temporarily suspended GMO corn because it threatens biodiversity. In the Colectividad del Maiz lawsuit, courts have prohibited Mexico from issuing commercial GMO permits while the litigation continues. Companies like Monsanto need these permits to sell GMO seeds. Corn is the most essential food item for millions of Mexicans and is central to Mexican culture. Mexicans wait for Colectividad del Maiz's resolution, siding with biodiversity or GMOs. This Article describes scientific GMO controversies and analyzes biosecurity, class-action, and international environmental law. It argues that this corn fight …

Small-Scale Variability In Carbon Isotope Ratios Of Microphytobenthos And Dissolved Inorganic Carbon In A Northern Gulf Of Mexico Salt Marsh, Trinity Curry, Jeffrey Krause, Ronald Baker

Gulf and Caribbean Research

No abstract provided.

Help-Seeking Behaviour For Fatigue In Inflammatory Bowel Disease, Doireann Ní Dhálaigh

Theses

Background: Fatigue is a common and burdensome symptom of inflammatory bowel disease (IBD). Although many symptoms of IBD can be debilitating, fatigue is reported to be the most burdensome. It is experienced by up to 86% of people in active disease and 41-48% in remission and impacts greatly on all aspects of people’s lives. Fatigue is an invisible symptom and can often be overlooked by healthcare professionals. Since it is invisible, it can only be made known to healthcare professionals if patients seek help for it. This study aims to explore the determinants of help-seeking behaviour for fatigue in IBD …

The Gastromyzophorous Tadpoles Of Atelopus Elegans And A. Palmatus (Anura: Bufonidae), With Comments On Oral And Suction Structures, Alejandro Marcillo-Lara, Luis A. Coloma, Sara Álvarez-Solas, Esteban Terneus

Neotropical Biodiversity

The tadpoles of the Neotropical genus Atelopus are only known for 26 out of 96 species described. Here, we describe the tadpoles of A. elegans and A. palmatus including ontogenetic information, measurements, and images of individuals in several stages of growth. Both species are compared with their congeners taking into account some relevant features such as the coloration and relative measurements. Our description focuses on the abdominal sucker and mouth by providing scanning electron microscopy images and comparing the suctorial mechanism with other groups of anurans and fish. We also provide an update to knowledge of the abdominal suckers, and …

Habitat Use By An Endemic And A Non-Native Gecko: Natural Habitat Provides A Last Refuge For The Barbados Leaf-Toed Gecko, Robert J. Williams, Julia A. Horrocks, Angelo P. Pernetta

Neotropical Biodiversity

Island endemic reptiles face many threats that potentially have a negative effect on their conservation status, such as habitat loss, interactions with introduced predators and competitors, and stochastic environmental events. Since confirmation of the continued existence of the Barbados Leaf Toed gecko (Phyllodactylus pulcher) on the island of Barbados, West Indies, efforts have been made to increase ecological knowledge of the gecko in order to inform conservation direction and safeguard this critically endangered endemic species. The present study is the first to determine the microhabitat use of P. pulcher and that of the non-native gecko Hemidactylus mabouia on Barbados, and …

First Records Of Diptera Associated With Human Corpses In Ecuador, Ana Belén García-Ruilova, Alvaro Barragán, Silvana Del C. Ordoñez, Juan F. García, Jose D. Mazón, René Cueva, David A. Donoso

Neotropical Biodiversity

Flies in the order Diptera are of forensic value because many species leave tractable evidence while harvesting nutrients from decomposing corpses. From December 2015 to January 2017, 41 fly specimens were collected in human bodies at crime scenes and autopsies across the south of Ecuador. Six species, e.g., Chrysomya albiceps (Widemann 1819), Chrysomya megacephala (Fabricius, 1794), Synthesiomyia nudiseta (Wulp, 1883), Lucilia purpurascens (Walker, 1836), Hemilucilia segmentaria (Fabricius, 1805), and Stomoxys calcitrans (Linneo, 1758) were identified to species level using morphological (dichotomous keys) and molecular (mitochondrial COI barcodes) techniques. One additional specimen remains unidentified to species level, but COI barcodes assigned …

Habitat Simplification Changes Temporal Patterns Of Invertebrate Beta Diversity In A High-Andean Stream, Juan David González-Trujillo, Yenni Lizeth Alonso-Moreno

Neotropical Biodiversity

Several studies have revealed that beta-diversity patterns are tightly coupled to differences in habitat heterogeneity and the spatial distance among headwaters. However, addressing the relative role of these factors over time is yet to be done, particularly in those factors acting at the local scale. Here, we investigated the temporal responses of stream invertebrate communities to habitat simplification and flow variability in two stretches of a high-Andean stream: an undisturbed and a channelized stretch. Both stretches were sampled every month in two hydrologically different years: a “regular year” and a year under the influence of the La Niña phenomenon. Using …

The Use Of Mycobacteriophages As A Novel Therapeutic Option To Control And Treat Johne's Disease, Gillian Catherine Crowley

Theses

The incidences of Johne’s disease (JD) in farms worldwide have increased significantly over the last 80 years. The increase in JD is owing to the lack of diagnostic tests available and the long incubation period of the disease causing pathogen, Mycobacterium avium paratuberculosis (MAP). In addition, treatment of JD with antibiotics has proven difficult due to the emergence of antibiotic resistance MAP strains and the presence of the thick lipid rich mycobacterial cell wall. An alternative diagnostic and treatment method for JD involves the use of mycobacteriophages. As part of this research, individual mycobacteriophages (TM4) and a mycobacteriophage cocktail (LE1 …

Role Of Sodium And Potassium In The Diet Of School-Aged Children In Ireland: Findings From The National Children’S Food Survey Ii, Eoin James Morrissey

Theses

A high sodium to potassium intake ratio (Na:K) resulting from a diet high in sodium and low in potassium can increase the risk of elevated blood pressure or hypertension in children, potentially leading to increased CVD in adulthood. The objective of this thesis was to estimate sodium and potassium intakes and Na:K in school-aged children (5-12y) in Ireland using data from the nationally representative National Children’s Food Survey II (NCFS II) (2017-18). The thesis study collected detailed dietary intake data for 600 children using 4-d food records and also collected spot urine samples from 95% of these participants. Sodium and …

Zoning For Families, Sara C. Bronin

Cornell Law Faculty Publications

Is a group of eight unrelated adults and three children living together and sharing meals, household expenses, and responsibilities—and holding themselves out to the world to have long-term commitments to each other—a family? Not according to most zoning codes—including that of Hartford, Connecticut, where the preceding scenario presented itself a few years ago. Zoning, which is the local regulation of land use, almost always defines family, limiting those who may live in a dwelling unit to those who satisfy the zoning code’s definition. Often times, this definition is drafted in a way that excludes many modern living arrangements and preferences. …

Ground Beetle (Coleoptera: Carabidae) Assemblages In Native, Invasive, And Encroaching Grassland Habitats, Madison Pittenger

Master's Theses or Doctor of Nursing Practice

Ground beetles (Carabidae) are increasingly used as ecological indicators in studies regarding land use because they are ubiquitous, respond quickly to environmental change, have a well-understood taxonomy, and can be trapped with ease. While the effects of various plant communities on ground beetle assemblages are relatively well-known, past studies have operated within boreal and tropical forests and have not placed much emphasis on the effects of native and nonnative species. In this study, ground beetles were investigated as indicators of invasion in a grassland setting. Ground beetles were sampled using pitfall traps throughout the 2018 growing season at Quivira National …

The Impact Of Socio-Economic Status, Life History, And Biological Sex On Affective Empathy In Adults, Shadow R. Love

Master's Theses or Doctor of Nursing Practice

ABSTRACT

A discussion of affective (or emotional) empathy as it is impacted by socioeconomic status (SES), life history, and biological sex is presented. The current study examined a gap in prior research by examining the interaction between these three variables and affective empathy. Participants were 504 adults between the ages of 18-68, with average age of 37 and primarily biological sex male (64%). Ethnicity varied with the majority as White/Caucasian (68.8%) followed in descending response rate by Hispanic or Latino/a, Black or African American, Asian, Native American or American Indian, and Native Hawaiian or Pacific Islander and 1.6% as two …

The Influence Of Landscape Factors On Black-Tailed Prairie Dog (Cynomys Ludovicianus) Colony Persistence In Northwest Kansas, Jamie Oriez

Master's Theses or Doctor of Nursing Practice

The black-tailed prairie dog (Cynomys ludovicianus) is a colonial and fossorial rodent species that serves as an ecosystem engineer and keystone species in North America’s grasslands. Black-tailed prairie dogs historically ranged from northern Mexico to southern Canada, and from eastern Nebraska to the foothills of the Rocky Mountains. However, with the loss and fragmentation of grasslands, introduction of Sylvatic plague (Yersinia pestis), and control measures such as poisoning and shooting, black-tailed prairie dogs are limited to less than 5 percent of their historical range.

In this study, I examined how colony area, location, isolation, and surrounding …

Guiding Students To Success: A Systematic Review Of Research On Guided Notes As An Instructional Strategy From 2009-2019, Bryan Biggers, Tian Luo

STEMPS Faculty Publications

Guided notes were introduced decades ago, but there is still debate over their efficacy in improving student outcomes. The purpose of this study is to examine peer-reviewed research on guided notes for adult learners in general populations since 2009, understanding the effects of guided notes on student learning, the knowledge and content areas supported by guided notes, and the impact of modality. Results of the 22 included studies indicate that students perceive guided notes in a positive light, and guided notes improve results in certain knowledge domains especially with complex content. However, modality does not influence the efficacy of guided …

An Assessment Of Convergence In The Feeding Morphology Of Xiphactinus Audax And Megalops Atlanticus Using Landmark-Based Geometric Morphometrics, Edward Chase Shelburne

Master's Theses or Doctor of Nursing Practice

Convergence is an evolutionary phenomenon wherein distantly related organisms independently develop features or functional adaptations to overcome similar environmental constraints. Historically, convergence among organisms has been speculated or asserted with little rigorous or quantitative investigation. More recent advancements in systematics has allowed for the detection and study of convergence in a phylogenetic context, but this does little to elucidate convergent anatomical features in extinct taxa with poorly understood evolutionary histories. The purpose of this study is to investigate one potentially convergent system—the feeding structure of Xiphactinus audax (Teleostei: Ichthyodectiformes) and Megalops atlanticus (Teleostei: Elopiformes)—using a comparative anatomical approach to assess …

The Influence Of Land Use On The Pollen Diet Of Honey Bee (Apis Mellifera) Colonies In Ellis County, Kansas, Ryan Engel

Master's Theses or Doctor of Nursing Practice

Pollinators are integral to plant ecology as well as to worldwide food availability and security. Understanding how human-driven land use change impacts the nutrition of managed honey bees is important in pollinator conservation efforts and can contribute towards combating recent pollinator declines. The objective of this study was to determine sources of forage for honey bees across different land use types in Ellis County, Kansas, through pollen analysis and taxonomic identification. Replicate study colonies were placed in three separate land use types: Urban, Cropland, or Native/Semi-native prairie. Pollen was sampled every 7 to 14 days throughout a growing season (April …

The Effects Of Prescribed Burning And Microhabitat Type On Ant (Formicidae) Functional Groups And A Survey Of Ants In The Dr. Howard Reynolds Nature Area (A Mixed Grass Prairie), Ashley N. Durr

Master's Theses or Doctor of Nursing Practice

This project sought to understand how prescribed burning and microhabitat type impacts Kansas ant functional groups and also whether prescribed burning in different microhabitat types altered the burn’s impact on those functional groups. The Dr. Howard Reynolds Nature Trail, located in Hays, Kansas, was burned in the spring of 2019. The area consists of 2 distinct habitat types: a dry, mixed-grass dominated uphill area and a moist, densely vegetated downhill area. Pitfall trapping was conducted during the summers of the year prior to the burn (2018) and the year following the burn (2019). 15 pitfall traps were spread across each …

Understanding Resilience: Investigating The Relationship Between Risk Factors, Resilience, And Psychological Well-Being, Paulyna Schulz

Master's Theses or Doctor of Nursing Practice

Numerous studies have indicated that adversity serves as a primary antecedent in the development of psychological resilience, however, adversity can have negative effects on psychological well-being. The current study focused on contributing to present literature by further investigating the roles of protective factors and adverse childhood experiences (ACEs) on resilience development, as well as the relationship between risk factors, resilience, and psychological well-being in adulthood. It was hypothesized that ACEs would predict the development of resilience when protective factors were high. It was also hypothesized that resilience positively influences the relationship between risk factors and psychological well-being by negating the …

Effect Of Thermocycling On The Colour Stability Of Aesthetic Restorative Materials: An In-Vitro Spectrophotometric Analysis, Swastika Bhattacharya, Tina Puthen Purayil, Kishore Ginjupalli, Sandya Kini

Open Access archive

Objective: To compare the color stability of Cention N, Fuji IX GP Extra, and Fuji IX GP after thermocycling. Material and Methods: Ten discs of each material of dimension 10 x 1 mm were prepared using a split mold. The preparations of the specimens were done according to the powder/liquid ratio as recommended by the manufacturers [4.6:1, 3.4:1 and 3.6:1 for the groups I, II, and III respectively]. After setting, the samples were retrieved, and the thickness of each specimen was measured using a micrometer at five different locations. The specimens with variations in thickness, porosity or cracks were discarded …

Role Of Mirna Clusters In Epithelial To Mesenchymal Transition In Cancer, Vaibhav Shukla, Divya Adiga, Padacherri Vethil Jishnu, Vinay Koshy Varghese

Open Access archive

Epithelial to mesenchymal transition (EMT) is a multistep biological process in which epithelial cells acquire characteristics of mesenchymal cells. Inappropriate activation of EMT contributes to the acquisition of pro-metastatic characteristics and cancer progression. EMT process involves the downregulation of epithelial markers (EpCAM, CDH1) and upregulation of mesenchymal markers (VIM, CDH2) and EMT-transcription factors (ZEB1/2, TWIST1/2, SNAI1, SLUG). MicroRNAs, a class of non-coding RNA post-transcriptionally govern gene expression by binding to the target mRNAs. A large proportion of miRNAs occur as miRNA clusters consisting of two or more miRNA coding genes. MiRNA clusters are reported to regulate diverse biological functions, including …

The Persisting Threats Of Cholera: A Cyclical Public Health Problem In Ghana, Rita Laryea Amediavor

Browse all Theses and Dissertations

The prevalence of communicable diseases continues to be one of the continent's leading causes of deaths. Cholera is a waterborne disease triggered by toxigenic strains of the Gram-negative bacteria Vibrio Cholerae O1 strain and less common O139 strain. with symptoms such as severe acute watery diarrhea and vomiting leading to dehydration, progressing to hypovolemic shock and death if not treated timely due to its short incubation period (Pasetto et al., 2018). West African countries are largely portrayed as endemic to cholera, though the dynamics of outbreaks in these developing countries remain largely uncertain. The purpose of the study is to …

Topological Analysis Of Averaged Sentence Embeddings, Wesley J. Holmes

Browse all Theses and Dissertations

Sentence embeddings are frequently generated by using complex, pretrained models that were trained on a very general corpus of data. This thesis explores a potential alternative method for generating high-quality sentence embeddings for highly specialized corpora in an efficient manner. A framework for visualizing and analyzing sentence embeddings is developed to help assess the quality of sentence embeddings for a highly specialized corpus of documents related to the 2019 coronavirus epidemic. A Topological Data Analysis (TDA) technique is explored as an alternative method for grouping embeddings for document clustering and topic modeling tasks and is compared to a simple clustering …