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2020

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A Social Review Of The Opioid Epidemic: The History, Pathophysiology, And Effects On Rural America, Holly J. Goehring Jan 2020

A Social Review Of The Opioid Epidemic: The History, Pathophysiology, And Effects On Rural America, Holly J. Goehring

Biology and Microbiology Graduate Students Plan B Research Projects

One of the more pressing issues in modern day health care is the nationwide heath care crisis known as the opioid epidemic. The beginning of this literature review will focus on the history of opioid use and early prescription rates, as well as the summary and definitions of the drugs involved in the current opioid epidemic. The review then shifts to the pathophysiology of addiction involving the activation of opioid receptors and opioid use disorder. The main focus of this literature review is the societal impacts of the opioid epidemic, making special reference to the economic burden and effects on …

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Antidepressant Effects On Rem Sleep, Mitchel Adams Jan 2020

Antidepressant Effects On Rem Sleep, Mitchel Adams

Biology and Microbiology Graduate Students Plan B Research Projects

Individuals who deal with depression are typically prescribed antidepressants in order to alleviate the depressive symptoms that they may be having. Polysomnographic sleep research has revealed that depression is associated with altered sleep architecture and distorted REM sleep quality.2 Specifically, increased REM sleep duration and density have proved to be markers that predict recurrence and relapse for depressed individuals. REM sleep serves to stimulate regions of the brain that are important with learning and memory consolidation. However, an increased duration of REM sleep in depressed individuals proves to be unfavorable. Antidepressants drugs aim to weaken sleep quality, which is …

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Deciphering The Past To Inform The Future: Preparing For The Next (“Really Big”) Extreme Event, Debra Pc Peters, N Dylan Burruss, Gregory S. Okin, Jerry L. Hatfield, Stacey Lp Scroggs, Haitao Huang, Colby W. Brungard, Jin Yao Jan 2020

Deciphering The Past To Inform The Future: Preparing For The Next (“Really Big”) Extreme Event, Debra Pc Peters, N Dylan Burruss, Gregory S. Okin, Jerry L. Hatfield, Stacey Lp Scroggs, Haitao Huang, Colby W. Brungard, Jin Yao

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Climate change will bring more extremes in temperature and precipitation that will impact productivity and ecosystem resilience throughout agroecosystems worldwide. Historical events can be used to identify drivers that impact future events. A catastrophic drought in the US in the 1930s resulted in an abrupt boundary between areas severely impacted by the Dust Bowl and areas that were less severely affected. Historical primary production data confirmed the location of this boundary at the border between two states (Nebraska and Iowa). Local drivers of weather and soils explained production responses across the boundary before and after the drought (1926–1948). During the …

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University Of Texas At Tyler Catalog, 2020 - 2021, University Of Texas At Tyler Jan 2020

University Of Texas At Tyler Catalog, 2020 - 2021, University Of Texas At Tyler

Catalogs

No abstract provided.

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Graduate Bulletin, 2020-2021, Minnesota State University Moorhead Jan 2020

Graduate Bulletin, 2020-2021, Minnesota State University Moorhead

Graduate Bulletins (Catalogs)

No abstract provided.

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Structural Dynamics Of Inosine Triphosphate Pyrophosphatase (Itpa) Protein And Two Clinically Relevant Mutants: Molecular Dynamics Simulations, Yao Houndonougbo, Bethany Pugh, Kandise Vanwormer, Caitlin April, Nicholas Burgis Jan 2020

Structural Dynamics Of Inosine Triphosphate Pyrophosphatase (Itpa) Protein And Two Clinically Relevant Mutants: Molecular Dynamics Simulations, Yao Houndonougbo, Bethany Pugh, Kandise Vanwormer, Caitlin April, Nicholas Burgis

Chemistry and Biochemistry Faculty Publications

The inosine triphosphate pyrophosphatase (ITPA) protein is responsible for removing noncanonical purine nucleoside triphosphates from intracellular nucleotide pools. Absence of ITPA results in genomic instability and increased levels of inosine in DNA and RNA. The proline to threonine substitution at position 32 (P32T) affects roughly 15% of the global population and can modulate treatment outcomes for cancer, lupus, and hepatitis C patients. The substitution of arginine with cysteine at position 178 (R178C) is extremely uncommon and has only been reported in a small cohort of early infantile encephalopathy patients suggesting that a functional ITPA protein is required for life in …

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Impacts Of Rock Climbing On Lichen And Bryophyte Cliff Communities In The Arid West, Giovanna M. Bishop Jan 2020

Impacts Of Rock Climbing On Lichen And Bryophyte Cliff Communities In The Arid West, Giovanna M. Bishop

2020 Symposium Posters

Lichens and bryophytes make up the majority of the diversity and cover in cliff systems around the world. Recently, with the rapid rise of rock climbing, there are concerns rock climbers are negatively impacting cliff communities. My study will compare climbed and unclimbed granite cliffs to better understand the impacts of rock climbing on lichen and bryophyte diversity and cover in eastern Washington. The objectives of this study are to assess the impacts of rock climbing on lichen and bryophyte cliff community diversity and cover and improve route development and cliff management practices for lichens and bryophytes. This study will …

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Invasive Species Shift Fungal Driven Decomposition In Midwestern Forests, Adam M. Reed Jan 2020

Invasive Species Shift Fungal Driven Decomposition In Midwestern Forests, Adam M. Reed

Browse all Theses and Dissertations

Midwestern forests are currently impacted by two prominent invaders, Agrilus planipennis and Lonicera maackii. The Ag. planipennis induced loss of Fraxinus spp. trees can facilitate Lo. maackii invasion, which is likely altering microbial driven forest nutrient cycling. To assess these changes in microbial processes, I conducted litter bag and culture-based decomposition experiments using leaf litter from Acer spp., Quercus spp., F. nigra, F. pennsylvanica, Lindera benzoin, and Lo. maackii. For the culture-based decomposition experiment, I inoculated six species of fungi separately onto both single species and multispecies (half Lo. maackii and half native spp.) leaf litter and measured decomposition rate, …

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Improving Pain Management In Patients With Sickle Cell Disease Using Machine Learning Techniques, Fan Yang Jan 2020

Improving Pain Management In Patients With Sickle Cell Disease Using Machine Learning Techniques, Fan Yang

Browse all Theses and Dissertations

Sickle cell disease (SCD) is an inherited red blood cell disorder that can cause a multitude of complications throughout a patient's life. Pain is the most common complication and a significant cause of morbidity. Since pain is a highly subjective experience, both medical providers and patients express difficulty in determining ideal treatment and management strategies for pain. Therefore, the development of objective pain assessment and pain forecasting methods is critical to pain management in SCD. On the other hand, the rapidly increasing use of mobile health (mHealth) technology and wearable devices gives the ability to build a remote health intervention …

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Reflection And Inquiry-Based Teaching: Exploring Reflective Practices In Beginning Secondary Science Teachers, Ana Rivero, Elizabeth B. Lewis Jan 2020

Reflection And Inquiry-Based Teaching: Exploring Reflective Practices In Beginning Secondary Science Teachers, Ana Rivero, Elizabeth B. Lewis

Department of Teaching, Learning, and Teacher Education: Faculty Publications

Science teachers’ reflections can be used as an opportunity to improve teaching through inquiry-based instruction (White, Frederiksen, & Collins, 2009), especially during their first years as teachers. Yet more work is still needed to support the development of beginning teachers’ reflective practices (Russell & Martin, 2014). The purpose of this exploratory multi-methods study was to describe: (a) beginning secondary science teachers’ reflective practices up to 4 years after completing their teacher education program, (b) the factors that might have an effect on these practices for participants, and (c) the connection (if any) between their inquiry-based instruction and reflective practices. We …

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Educating Effective Science Teachers: Preparing And Following Teachers Into The Field, Elizabeth Lewis, Ana Rivero, Aaron Musson, Lyrica L. Lucas, Amy Tankersley, Brandon Helding Jan 2020

Educating Effective Science Teachers: Preparing And Following Teachers Into The Field, Elizabeth Lewis, Ana Rivero, Aaron Musson, Lyrica L. Lucas, Amy Tankersley, Brandon Helding

Department of Teaching, Learning, and Teacher Education: Faculty Publications

This chapter focuses on: (a) our development of a research-based, graduate- level science TPP for teachers with a degree in science; (b) an analysis of teachers’ subject matter knowledge (SMK) as it relates to their subsequent use of inquiry-based instruction; and (c) results of a longitudinal study of beginning science teachers who graduated from a master’s level TPP in comparison with the instructional practices of science teachers prepared through a traditional undergraduate program. We offer what we consider to be a typical case of an undergraduate and less typical case of a graduate science teacher preparation program that occur at …

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Evidence-Based Health Solutions For Challenges Women Face During Pandemics Like Covid-19: A Systematic Review Protocol, Zhaohui Su, Shelly Wagers, Emme Lopez, Lori Ann Terjesen, Jaffar Abbas, Feng Shi, Caifeng Wang, Yuyang Cai Jan 2020

Evidence-Based Health Solutions For Challenges Women Face During Pandemics Like Covid-19: A Systematic Review Protocol, Zhaohui Su, Shelly Wagers, Emme Lopez, Lori Ann Terjesen, Jaffar Abbas, Feng Shi, Caifeng Wang, Yuyang Cai

Criminology Faculty Publications

No abstract provided.

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Renca Macrobeads Inhibit Tumor Cell Growth Via Egfr Activation And Regulation Of Mef2 Isoform Expression, Prithy Caroline Martis Jan 2020

Renca Macrobeads Inhibit Tumor Cell Growth Via Egfr Activation And Regulation Of Mef2 Isoform Expression, Prithy Caroline Martis

Browse all Theses and Dissertations

Tumors are heterogeneous systems, whose growth is influenced by intrinsic properties of malignant cells, external systemic factors (i.e. immune, neural, endocrine, etc.), and the dynamic interactions between tumor cells and their microenvironment. Given the inherent complexity of cancers, combined with the continual evolution of tumors and the development of treatment resistance, a precision medicine approach may not provide an optimal clinical response. Exploring a new paradigm that focuses on regulating cancer as a system may not only control tumor progression but also address the extraordinary challenges of tumor heterogeneity and disease recurrence in order to improve clinical outcomes. As a …

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Characterization Of B3galt2 And Heg1 Expression In Dorsal Root Ganglia, Alexander H. Nguyen Jan 2020

Characterization Of B3galt2 And Heg1 Expression In Dorsal Root Ganglia, Alexander H. Nguyen

Browse all Theses and Dissertations

Proprioception provides unique sensory feedback about the body’s orientation in space and this sensation is essential for creating specific motor functions and coordinated movement. During neurogenesis, unique genetic markers are expressed and classified as early, transient/middle, and late markers depending on their timing of expression. This study focuses on the expression patterns of two late markers: Heg1 and B3galt2. We investigated how expression of these two markers respond to peripheral nerve injury (PNI). We cloned and generated riboprobes to detect expression of B3galt2 and Heg1 in DRGs using in situ hybridization after transection of the sciatic nerve. B3galt2 hybridization in …

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Correlations Between Quality Of Life, Daily Sunlight, And Suicide Risk, Brittany Abeldt Jan 2020

Correlations Between Quality Of Life, Daily Sunlight, And Suicide Risk, Brittany Abeldt

Scholarship in Medicine - All Papers

Methods: Data was collected from the archives provided by the CDC Wonder database; including The Behavioral Risk Factor Surveillance System, The North America Land Data Assimilation System, and The Web-Based Injury Statistic Query and Reporting System. The variables used were quality of life (as measured by mental health days and physical health days), suicide rates, and daily sunlight. Data was obtained for all the states in the United States, excluding Alaska and Hawaii due to lack of available data from these states. Quality of life and suicide rate data was from 2016 and daily sunlight data was from January 1st, …

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Growing Green Minds: Implementation Of A School Garden & Nutrition Program For The Freedom Area School District In Rural Wisconsin, Marissa Schuh Jan 2020

Growing Green Minds: Implementation Of A School Garden & Nutrition Program For The Freedom Area School District In Rural Wisconsin, Marissa Schuh

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Most children in the U.S. consume too few fruits and vegetables which is putting them at risk to develop obesity and other lifestyle diseases. The 2015-2020 Dietary Guidelines for Americans recommends that individuals should increase the amount and variety of fruits and vegetables consumed in order to prevent weight gain and other chronic diseases. Research shows that garden-based educational programs can increase children’s fruit and vegetable intake as well as change their preferences and attitudes towards eating and trying new fruits and vegetables. Incorporating a garden and nutrition curriculum into a school setting is an ideal opportunity to improve children’s …

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Mariana Serpentinite Mud Volcanism Exhumes Subducted Seamount Materials: Implications For The Origin Of Life, Patricia Freyer, C. G. Wheat, Trevor Williams, Christopher Kelley, Kevin Johnson, Jeffrey Ryan, Walter Kurz, John Shervais, Elmar Albers, Barbara Bekins Jan 2020

Mariana Serpentinite Mud Volcanism Exhumes Subducted Seamount Materials: Implications For The Origin Of Life, Patricia Freyer, C. G. Wheat, Trevor Williams, Christopher Kelley, Kevin Johnson, Jeffrey Ryan, Walter Kurz, John Shervais, Elmar Albers, Barbara Bekins

School of Geosciences Faculty and Staff Publications

The subduction of seamounts and ridge features at convergent plate boundaries plays an important role in the deformation of the overriding plate and influences geochemical cycling and associated biological processes. Active serpentinization of forearc mantle and serpentinite mud volcanism on the Mariana forearc (between the trench and active volcanic arc) provides windows on subduction processes.  Here, we present (1) the first observation of an extensive exposure of an undeformed Cretaceous seamount currently being subducted at the Mariana Trench inner slope; (2) vertical deformation of the forearc region related to subduction of Pacific Plate seamounts and thickened crust; (3) recovered Ocean …

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Scientist Of The Week!, Sarah L. Sheffield, Lisette Melendez, Kristin Houdyshell, Mathew Burgos Jan 2020

Scientist Of The Week!, Sarah L. Sheffield, Lisette Melendez, Kristin Houdyshell, Mathew Burgos

School of Geosciences Faculty and Staff Publications

No abstract provided.

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Boosting Computational Effectiveness In Big Spatial Flow Data Analysis With Intelligent Data Reduction, Ran Tao, Zhaoya Gong, Qiwei Ma, Jean-Claude Thill Jan 2020

Boosting Computational Effectiveness In Big Spatial Flow Data Analysis With Intelligent Data Reduction, Ran Tao, Zhaoya Gong, Qiwei Ma, Jean-Claude Thill

School of Geosciences Faculty and Staff Publications

One of the enduring issues of spatial origin-destination (OD) flow data analysis is the computational inefficiency or even the impossibility to handle large datasets. Despite the recent advancements in high performance computing (HPC) and the ready availability of powerful computing infrastructure, we argue that the best solutions are based on a thorough understanding of the fundamental properties of the data. This paper focuses on overcoming the computational challenge through data reduction that intelligently takes advantage of the heavy-tailed distributional property of most flow datasets. We specifically propose the classification technique of head/tail breaks to this end. We test this approach …

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Estimating Dispersal And Evolutionary Dynamics In Diploporan Blastozoans (Echinodermata) Across The Great Ordovician Biodiversification Event, Adriane R. Lam, Sarah L. Sheffield, Nicholas J. Matzke Jan 2020

Estimating Dispersal And Evolutionary Dynamics In Diploporan Blastozoans (Echinodermata) Across The Great Ordovician Biodiversification Event, Adriane R. Lam, Sarah L. Sheffield, Nicholas J. Matzke

School of Geosciences Faculty and Staff Publications

Echinoderms make up a substantial component of Ordovician marine invertebrates, yet their speciation and dispersal history as inferred within a rigorous phylogenetic and statistical framework is lacking. We use biogeographic stochastic mapping (BSM; implemented in the R package BioGeoBEARS) to infer ancestral area relationships and the number and type of dispersal events through the Ordovician for diploporan blastozoans and related species. The BSM analysis was divided into three time slices to analyze how dispersal paths changed before and during the great Ordovician biodiversification event (GOBE) and within the Late Ordovician mass extinction intervals. The best-fit biogeographic model incorporated jump dispersal, …

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Uncovering Host-Microbiome Interactions In Global Systems With Collaborative Programming: A Novel Approach Integrating Social And Data Sciences [Version 1; Peer Review: Awaiting Peer Review], Jenna Oberstaller, Swamy Rakesh Adapa, Guy Dayhoff Ii, Justin Gibbons, Gregory S. Herbert Jan 2020

Uncovering Host-Microbiome Interactions In Global Systems With Collaborative Programming: A Novel Approach Integrating Social And Data Sciences [Version 1; Peer Review: Awaiting Peer Review], Jenna Oberstaller, Swamy Rakesh Adapa, Guy Dayhoff Ii, Justin Gibbons, Gregory S. Herbert

School of Geosciences Faculty and Staff Publications

Microbiome data are undergoing exponential growth powered by rapid technological advancement. As the scope and depth of microbiome research increases, cross-disciplinary research is urgently needed for interpreting and harnessing the unprecedented data output. However, conventional research settings pose challenges to much-needed interdisciplinary research efforts due to barriers in scientific terminologies, methodology and research-culture. To breach these barriers, our University of South Florida OneHealth Codeathon was designed to be an interactive, hands-on event that solves real-world data problems. The format brought together students, postdocs, faculty, researchers, and clinicians in a uniquely cross-disciplinary, team-focused setting. Teams were formed to encourage equitable distribution …

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F2.3 Seasonal Freshwater Lakes, R. T. Kingsford, R. Mac Nally, Mark C. Rains, B. J. Robson, K. Irvine, D. A. Keith Jan 2020

F2.3 Seasonal Freshwater Lakes, R. T. Kingsford, R. Mac Nally, Mark C. Rains, B. J. Robson, K. Irvine, D. A. Keith

School of Geosciences Faculty and Staff Publications

No abstract provided.

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F1.1 Permanent Upland Streams, R. T. Kingsford, R. Mac Nally, P. S. Giller, Mark C. Rains, M. Kelly-Quinn, A. H. Arthington, D. A. Keith Jan 2020

F1.1 Permanent Upland Streams, R. T. Kingsford, R. Mac Nally, P. S. Giller, Mark C. Rains, M. Kelly-Quinn, A. H. Arthington, D. A. Keith

School of Geosciences Faculty and Staff Publications

No abstract provided.

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Serpentinization As A Route To Liberating Phosphorus On Habitable Worlds, Matthew Pasek, Arthur Omran, Carolyn Lang, Maheen Gull, Josh Abbatiello, Tian Feng, Lyle Garong, Heather Abbott-Lyon Jan 2020

Serpentinization As A Route To Liberating Phosphorus On Habitable Worlds, Matthew Pasek, Arthur Omran, Carolyn Lang, Maheen Gull, Josh Abbatiello, Tian Feng, Lyle Garong, Heather Abbott-Lyon

School of Geosciences Faculty and Staff Publications

Planetary habitability is in part governed by nutrient availability, including the availability of the element phosphorus. The nutrient phosphorus plays roles in various necessary biochemical functions, and its biogeochemical cycling has been proposed to be extremely slow due to a strong coupling to the rock cycle via mineral weathering. Here we show a route to P liberation from water-rock reactions that are thought to be common throughout the Solar System. We report the speciation of phosphorus in serpentinite rocks to include the ion phosphite (HPO32- with P3+) and show that reduction of phosphate to phosphite is predicted from thermodynamic models …

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The Subject-Centered Integrative Learning Model: A New Model For Teaching Occupational Therapy’S Distinct Value, Barb Hooper, Matthew Molineux, Wendy Wood Jan 2020

The Subject-Centered Integrative Learning Model: A New Model For Teaching Occupational Therapy’S Distinct Value, Barb Hooper, Matthew Molineux, Wendy Wood

Journal of Occupational Therapy Education

The concept of occupation-centered education has been used to describe what programs do when they infuse occupation throughout an occupational therapy curriculum. In describing occupation-centered education, educators often describe the strategies they use to help students learn occupation, including courses about occupation, direct experience with occupation, cases and questions that connect biomedical sciences and health conditions to occupation, assignments that require students to infuse occupation into therapy, curriculum threads related to occupation, and many others. While each of these strategies is important, no conceptual model exists that defines occupation-centered education, elaborates its concepts and principles, and guides the development of …

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Development And Demography Of Larval Epicrionops Bicolor (Amphibia: Gymnophiona: Rhinatrematidae), Hendrik Müller Jan 2020

Development And Demography Of Larval Epicrionops Bicolor (Amphibia: Gymnophiona: Rhinatrematidae), Hendrik Müller

Neotropical Biodiversity

Information on even the most basic biological aspects is often missing for many species and even higher taxa of caecilians. As in other amphibians, development is plesiomorphically biphasic and aquatic larvae are present in Rhinatrematidae, Ichthyophiidae, and some Indotyphlidae. However, only very little information on larval morphology and ecology is available. Here I describe a series of Epicrionops bicolor larvae and metamorphs from Peru and provide details on the development of the annulation pattern, colouration, external gills, lateral line system, and other morphological characters and discuss the taxonomic value of lateral line characters. Specimens were collected at two different times …

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Test Of The Prey-Attraction Hypothesis For The Scorpion Fluorescence, Dumas Gálvez, Carolina Nieto, Paola Samaniego Jan 2020

Test Of The Prey-Attraction Hypothesis For The Scorpion Fluorescence, Dumas Gálvez, Carolina Nieto, Paola Samaniego

Neotropical Biodiversity

A striking feature of most scorpion species is fluorescence under ultraviolet light, but few studies have investigated the adaptive benefit of this trait. A hypothesis is that fluorescence may lure prey towards the scorpion improving foraging success. In this study, we investigated whether the fluorescence of the scorpion Centruroides granosus Thorell, 1876 lures the house cricket Acheta domesticus Linnaeus, 1758. We performed two experiments: 1) an arena in which crickets were exposed to both fluorescing and black-painted non-fluorescing scorpions and 2) a tunnel in which crickets could walk out through one of the two exits, each with a scorpion treatment. …

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Beyond Equality And Discrimination, Martha Albertson Fineman Jan 2020

Beyond Equality And Discrimination, Martha Albertson Fineman

Faculty Articles

The theme of this Article for the SMU Law Review Forum focuses us on the challenges faced by the “economically disadvantaged” in the past decade and in the future. This framing is rooted in a distinction between that conceptual status of equality and the actuality of discrimination and disadvantage. This is the lens through which contemporary legal culture tends to assess the nature and effect of existing laws and determines the necessary direction of reform. As such, this paradigm provides the governing logic for both criticism and justification of the status quo. It is rooted in an understanding of the …

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Treating Anemia Of Chronic Disease, Sarit Fischer Jan 2020

Treating Anemia Of Chronic Disease, Sarit Fischer

The Science Journal of the Lander College of Arts and Sciences

Anemia of chronic disease (ACD) is the result of altered iron metabolism, blunted erythropoiesis, and shortened red blood cell survival caused by inflammatory cytokines. Hepcidin plays a key role in anemia of chronic disease by inducing endocytosis of the iron exporter ferroportin. Iron is trapped in enterocytes, hepatocytes, and macrophages, and is unavailable for hemoglobin synthesis. When treating the underlying disease is not an option, or anemia is severe, ACD should be treated. While oral iron supplementation is not suitable for ACD, intravenous iron may be effective. Erythropoiesis stimulating agents are a common approach to treating ACD, but a large …

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Full Issue: Volume 14, Number 1, Fall 2020 Jan 2020

Full Issue: Volume 14, Number 1, Fall 2020

The Science Journal of the Lander College of Arts and Sciences

Complete .pdf file of Volume 14, number 1 of The Science Journal of the Lander College of Arts and Sciences. Published Fall 2020.

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