Digital Commons Network^™

Women For Ireland: Republican Feminism In The Northern Ireland Troubles, Laura Jacobsen

Theses and Dissertations

This paper studies the involvement of republican women in the Northern Ireland conflict, a struggle which defined life in Northern Ireland from 1969-1998. Too often, the Troubles, as the conflict is known, has been conceptualized as a struggle of men, while women are seen to be little more than suffering wives, girlfriends, and mothers. The image of “Mother Ireland” reinforces this notion: in this trope, Ireland is a woman begging for her sons to save her from British subjectivity. Similarly, contemporary feminist critics did not consider republican women to be equal to men. It was their belief that republican women …

Identifying Mcmi-Iv Personality Disorder Subgroups Using Exploratory Factor Analysis And Latent Class Analysis, Amanda Fisher

Theses and Dissertations

Patients diagnosed with personality disorders (PDs) have higher morbidity and mortality rates than those without PDs. The DSM-5 PD diagnoses and the cluster system lack a theoretical and empirical basis, which hinders the development of knowledge about PDs and interventions for PDs. This present study attempts to add to this literature by forming PD groups using a combination of exploratory factor analysis (EFA) and latent class analysis (LCA) based on PD scores from the Millon Clinical Multiaxial Inventory-IV (MCMI-IV), a method recommended by Gorman and Primavera (1983). Participants were 251 English speaking males and females ages 18 to 75 seeking …

Examining The Relationship Between Alzheimer’S Disease, Depression, And Social Support, Marko Lamela

Theses and Dissertations

This study examined the relationship between Alzheimer’s Disease and depression to determine whether a correlation existed and whether depression led to greater outcomes of Alzheimer’s Disease. Depression-Alzheimer’s relations have been mixed in previous research. Data from an existing data set of visitors to the Alzheimer’s Disease Centers with three or more visits (N= 19, 652) was used to test correlations between depression and Alzheimer’s, later odds of developing Alzheimer’s, and possible moderating effects of social support. A positive correlation was found between depression and Alzheimer’s Disease. Patients with depression were found to be more likely to have Alzheimer’s. There was …

Application Of A Biphasic Mathematical Model Of Cancer Cell Drug Response For Formulating Potent And Synergistic Targeted Drug Combinations To Triple Negative Breast Cancer Cells, Jinyan Shen, Li Li, Niall G. Howlett, Paul S. Cohen, Gongqin Sun

Cell and Molecular Biology Faculty Publications

Triple negative breast cancer is a collection of heterogeneous breast cancers that are immunohistochemically negative for estrogen receptor, progesterone receptor, and ErbB2 (due to deletion or lack of amplification). No dominant proliferative driver has been identified for this type of cancer, and effective targeted therapy is lacking. In this study, we hypothesized that triple negative breast cancer cells are multi-driver cancer cells, and evaluated a biphasic mathematical model for identifying potent and synergistic drug combinations for multi-driver cancer cells. The responses of two triple negative breast cancer cell lines, MDA-MB-231 and MDA-MB-468, to a panel of targeted therapy drugs were …

Tiamulin-Resistant Mutants Of The Thermophilic Bacterium Thermus Thermophilus, Erin E. Killeavy, Gerwald Jogl, Steven T. Gregory

Cell and Molecular Biology Faculty Publications

Tiamulin is a semisynthetic pleuromutilin antibiotic that binds to the 50S ribosomal subunit A site and whose (((2-diethylamino)ethyl)thio)-acetic acid tail extends into the P site to interfere with peptide bond formation. We have isolated spontaneous tiamulin-resistant mutants of the thermophilic bacterium Thermus thermophilus, containing either single amino acid substitutions in ribosomal protein uL3 or single base substitutions in the peptidyltransferase active site of 23S rRNA. These mutations are consistent with those found in other organisms and are in close proximity to the crystallographically determined tiamulin binding site. We also conducted a cross-resistance analysis of nine other single-base substitutions in …

Severe Food Restriction Activates The Central Renin Angiotensin System, Aline Maria De Souza, Andrea Linares, Robert C. Speth, Glenda V. Campos, Hong Ji, Deoclécio Chianca, Kathryn Sandberg, Rodrigo C. De Menezes

HPD Articles

We previously showed that 2 weeks of a severe food restricted (sFR) diet (40% of the caloric intake of the control (CT) diet) up-regulated the circulating renin angiotensin (Ang) system (RAS) in female Fischer rats, most likely as a result of the fall in plasma volume. In this study, we investigated the role of the central RAS in the mean arterial pressure (MAP) and heart rate (HR) dysregulation associated with sFR. Although sFR reduced basal mean MAP and HR, the magnitude of the pressor response to intracerebroventricular (icv) microinjection of Ang-[1-8] was not affected; however, HR was 57 ± 13 …

Doxycycline Hyclate, Reema S. Patel, Mayur S. Parmar

HPD Articles

No abstract provided.

Water Deficit Transcriptomic Responses Differ In The Invasive Tamarix Chinensis And T. Ramosissima Established In The Southern And Northern United States, Padmapriya Swaminathan, Michelle K. Ohrtman, Abigail Carinder, Anup Deuja, Cankun Wang, John Gaskin, Anne Fennell, Sharon Clay

Agronomy, Horticulture and Plant Science Faculty Publications

Tamarix spp. (saltcedar) were introduced from Asia to the southern United States as windbreak and ornamental plants and have spread into natural areas. This study determined differential gene expression responses to water deficit (WD) in seedlings of T. chinensis and T. ramosissima from established invasive stands in New Mexico and Montana, respectively. A reference de novo transcriptome was developed using RNA sequences from WD and well-watered samples. Blast2GO analysis of the resulting 271,872 transcripts yielded 89,389 homologs. The reference Tamarix (Tamaricaceae, Carophyllales order) transcriptome showed homology with 14,247 predicted genes of the Beta vulgaris subsp. vulgaris (Amaranthaceae, Carophyllales order) genome …

Examining The Monitoring Of Health Surveillance During A Pandemic: A Review Of Methodology, Jeffrey E. Jarrett

College of Business Faculty Publications

The goal is to examine a common problem is biological analytics and surveillance in health care. These methods can improve greatly the process of monitoring health data to assess changes in the likelihood of Pandemics and disease incidence in a world where medical knowledge is still largely in an embryonic period. Based on an illustration, we suggest that multivariate exponential moving-average (MEWMA) control charts are suitable in many cases where detection and inspection of several or more variables over a lengthy period of testing provide for the best analysis of data leading to pre-­diagnostic and diagnostic therapy. Though …

A Systemic Review And Meta-Analysis On The Antihypertensive Effect Of Aromatherapy Essential Oils, Mikyoung Lee, Ji-Ah Song, Mina Ahn, Ahra Jo, Jeongah Park, Wonjong Kim, Claudia M. Davis, Yeon Sook Kim, Myun-Haeng Hur

Nursing Faculty Publications

Purpose: This study is a systemic review of experimental results on the effects of aromatherapy on blood pressure.

Materials and Methods: Journal articles published to December, 2017, were retrieved from twelve databases. Randomized controlled trials in which were evaluated for changes in blood pressure following aromatherapy were selected. Risks of bias were assessed using the risk-of-bias (ROB) tool of the Cochrane Collaboration. Meta-analysis were dine using RevMan.

Results: Of the 2545 articles retrieved from the electronic databases, 580 duplicate articles and 1891 articles that were unrelated to the PICO (patient/problem, intervention, comparison, outcome) elements or did not satisfy the inclusion …

City Of Portsmouth, New Hampshire Annual Comprehensive Financial Report For The Year Ended June 30, 2020., Portsmouth Town Representatives

Portsmouth, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Virtual Undergraduate Research & Scholarship Competition Award Winners 2020, Office Of Research

Undergraduate Research and Scholarship Symposium

No abstract provided.

Effectiveness Of Complete Decongestive Therapy (Cdt) As A Lifestyle Management Intervention For Adults With Secondary Lymphedema., Hannah Curlett, Alexia Gallagher, Amy Shaver

Critically Appraised Topics

The National Cancer Institute (2019) explains that lymphedema is a condition where there is a buildup of fluid in soft tissues as a result of the lymphatic system being damaged or blocked. Lymphedema is estimated to impact 2 to 3 million people in the United States, with secondary lymphedema being the most common form (Rockson & Rivera, 2008). Prevalence rates for lymphedema are likely underestimated, as not all patients have received treatment for their condition (Rockson & Rivera, 2008). Secondary lymphedema occurs when the lymph system is damaged or blocked from cancer, infection, injury, removal of lymph nodes, radiation, or …

Sex-Segregated Range Use By Black-And-White Ruffed Lemurs (Varecia Variegata) In Ranomafana National Park, Madagascar, Andrea L. Baden, Jelisa Oliveras, Brian Gerber

Natural Resources Science Faculty Publications

Ranging behavior is one important strategy by which nonhuman primates obtain access to resources critical to their biological maintenance and reproductive success. As most primates live in permanent social groups, their members must balance the benefits of group living with the costs of intragroup competition for resources. However, some taxa live in more spatiotemporally flexible social groups, whose members modify patterns of association and range use as a method to mitigate these costs. Here, we describe the range use of one such taxon, the black-and-white ruffed lemur (Varecia variegata), at an undisturbed primary rain forest site in Ranomafana …

"Torture The Women": A Gaze At The Misogynistic Machinery Of Scary Cinema, Sarah Hankins

Copley Library Undergraduate Research Awards

A frightening truth remains that within horror-thriller films the experience of women is at the heart of the horrifying. This project analyses the effects of film media on the construction, fetishization, and destruction of female figures and engages with feminist critical concepts, such as Laura Mulvey’s “male gaze” and Linda Williams’ “body horror,” to evaluate Alfred Hitchcock’s film Vertigo (1958) and Satoshi Kon’s anime Perfect Blue (1997). Importantly, this essay critiques the misogynistic inner-workings of the horror-thriller genre typified in Vertigo—that evokes visual pleasure from objectification, victimization, and physical, often sexual, violence—and contrasts it with Kon’s anime. This paper finds …

Carbon Limitation In Periphytic Algal Wastewater Treatment Systems, Brandon Furnish, Troy Keller

CSU Datasets

This data set includes the results of 3 independent lab experiments that examined the role of carbon limitation in algal wastewater treatment systems.

Survivor's Guide To Probate And Trust Administration, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2020

Meeting proceedings of a seminar by the same name, held November 6, 2020.

Association Between Baseline Abundance Of Peptoniphilus, A Gram-Positive Anaerobic Coccus, And Wound Healing Outcomes Of Dfus, Kyung R. Min, Adriana Galvis, Katherine L. Baquerizo Nole, Rohita Sinha, Jennifer Clarke, Robert S. Kirsner, Dragana Ajdic

Department of Statistics: Faculty Publications

Diabetic foot ulcers (DFUs) lead to nearly 100,000 lower limb amputations annually in the United States. DFUs are colonized by complex microbial communities, and infection is one of the most common reasons for diabetes-related hospitalizations and amputations. In this study, we examined how DFU microbiomes respond to initial sharp debridement and off- loading and how the initial composition associates with 4 week healing outcomes. We employed 16S rRNA next generation sequencing to perform microbial profiling on 50 sam- ples collected from 10 patients with vascularized neuropathic DFUs. Debrided wound sam- ples were obtained at initial visit and after one week …

Representation Of Features As Images With Neighborhood Dependencies For Compatibility With Convolutional Neural Networks, Omid Bazgir, Ruibo Zhang, Saugato Rahman Dhruba, Raziur Rahman, Souparno Ghosh, Ranadip Pal

Department of Statistics: Faculty Publications

Deep learning with Convolutional Neural Networks has shown great promise in image-based classification and enhancement but is often unsuitable for predictive modeling using features without spatial correlations. We present a feature representation approach termed REFINED (REpresentation of Features as Images with NEighborhood Dependencies) to arrange high-dimensional vectors in a compact image form conducible for CNN-based deep learning. We consider the similarities between features to generate a concise feature map in the form of a two-dimensional image by minimizing the pairwise distance values following a Bayesian Metric Multidimensional Scaling Approach. We hypothesize that this approach enables embedded feature extraction and, integrated …

A High-Throughput Phenotyping Pipeline For Image Processing And Functional Growth Curve Analysis, Ronghao Wang

Department of Statistics: Faculty Publications

High-throughput phenotyping system has become more and more popular in plant science research. The data analysis for such a system typically involves two steps: plant feature extraction through image processing and statistical analysis for the extracted features. The current approach is to perform those two steps on different platforms. We develop the package “implant” in R for both robust feature extraction and functional data analysis. For image processing, the “implant” package provides methods including thresholding, hidden Markov random field model, and morphological operations. For statistical analysis, this package can produce nonparametric curve fitting with its confidence region for plant growth. …

Tumor Ablation Due To Inhomogeneous Anisotropic Diffusion In Generic Three-Dimensional Topologies, Erdi Kara, Aminur Rahman, Eugenio Aulisa, Souparno Ghosh

Department of Statistics: Faculty Publications

In recent decades computer-aided technologies have become prevalent in medicine, however, cancer drugs are often only tested on in vitro cell lines from biopsies. We derive a full three-dimensional model of inhomogeneous -anisotropic diffusion in a tumor region coupled to a binary population model, which simulates in vivo scenarios faster than traditional cell-line tests. The diffusion tensors are acquired using diffusion tensor magnetic resonance imaging from a patient diagnosed with glioblastoma multiform. Then we numerically simulate the full model with finite element methods and produce drug concentration heat maps, apoptosis hotspots, and dose-response curves. Finally, predictions are made about optimal …

Statistical Downscaling With Spatial Misalignment: Application To Wildland Fire Pm2.5 Concentration Forecasting, Suman Majumder, Yawen Guan, Brian J. Reich, Susan O’Neill, Ana G. Rappold

Department of Statistics: Faculty Publications

Fine particulate matter, PM_2.5, has been documented to have adverse health effects, and wildland fires are a major contributor to PM_2.5 air pollution in the USA. Forecasters use numerical models to predict PM_2.5 concentrations to warn the public of impending health risk. Statistical methods are needed to calibrate the numerical model forecast using monitor data to reduce bias and quantify uncertainty. Typical model calibration techniques do not allow for errors due to misalignment of geographic locations. We propose a spatiotemporal downscaling methodology that uses image registration techniques to identify the spatial misalignment and accounts for and …

At: A Hydro-Economic Modeling Framework For Aquifer Management In Irrigated Agricultural Regions☆, Mani Rouhi Rad, Erin M.K. Haacker, Vaishali Sharda, Soheil Nozari, Zaichen Xiang, A. Araya, Venkatesh Uddameri, Jordan F. Suter, Prasanna Gowda

Department of Earth and Atmospheric Sciences: Faculty Publications

In this paper, we introduce a hydro-economic modeling framework for the management of groundwater resources that are used for irrigated agricultural production. The model, MOD$$AT, can be used to study the costs of aquifer depletion and the net benefits of specific aquifer management policies. MOD$$AT is composed of three components, namely, an economic component, a hydrologic component and an agronomic component. A main goal of this paper is to introduce the hydro-economic model and describe how it can be transferable to different contexts. With this objective in mind, we describe model components step-by-step so that the process of integration can …

Virtual Drug Repurposing Study Against Sars-Cov-2 Tmprss2 Target, Serdar Durdaği

Turkish Journal of Biology

Currently, the world suffers from a new coronavirus SARS-CoV-2 that causes COVID-19. Therefore, there is a need for the urgent development of novel drugs and vaccines for COVID-19. Since it can take years to develop new drugs against this disease, here we used a hybrid combined molecular modeling approach in virtual drug screening repurposing study to identify new compounds against this disease. One of the important SARS-CoV-2 targets namely type 2 transmembrane serine protease (TMPRSS2) was screened with NPC's NIH small molecule library which includes approved drugs by FDA and compounds in clinical investigation. We used 6654 small molecules in …

The Effects Of Modifiable And Non-Modifiable Risk Factors On The Severity Of Gastroparesis-Like Symptoms, Jonathon B. Nelson

Honors Undergraduate Theses

Gastroparesis (GP) is a clinical disorder recognized by measured delayed gastric emptying without mechanical obstruction, in addition to symptoms such as nausea, vomiting, chronic abdominal pain, heartburn, early satiety upon eating a regular-sized meal, and exaggerated postprandial fullness. While GP is considered a clinically rare disorder, there is much suspicion that a much larger number of patients experience GP-like symptoms without an official diagnosis. Furthermore, little work has been done to identify the causes and exacerbations of this gastrointestinal (GI) distress in the young adult population. This study's primary goal was to establish a relationship between modifiable and non-modifiable risk …

Expanding The Evolutionary Explanations For Sex Differences In The Human Skeleton, Holly M. Dunsworth

Sociology and Anthropology Faculty Publications

While the anatomy and physiology of human reproduction differ between the sexes, the effects of hormones on skeletal growth do not. Human bone growth depends on estrogen. Greater estrogen produced by ovaries causes bones in female bodies to fuse before males' resulting in sex differences in adult height and mass. Female pelves expand more than males' due to estrogen and relaxin produced and employed by the tissues of the pelvic region and potentially also due to greater internal space occupied by female gonads and genitals. Evolutionary explanations for skeletal sex differences (aka sexual dimorphism) that focus too narrowly on big …

Editorial: Integrating Predation Risk Across Scales: From Neurons To Ecosystems And Milliseconds To Generations, Jacqueline J. Blundell, Evan L. Preisser

Biological Sciences Faculty Publications

No abstract provided.

Seasonal Changes In Eastern Hemlock (Tsuga Canadensis) Foliar Chemistry, Ian G. Kinahan, Chad M. Rigsby, Suzanne K. Savage, Nick L. Houseman, Andrew S. Marsella, Anita Oppong, Brenton L. Deboef, Colin M. Orians, Evan L. Preisser

Biological Sciences Faculty Publications

Eastern hemlock (Tsuga canadensis (L.) Carriére; hemlock) is an eastern North American conifer threatened by the invasive hemlock woolly adelgid (Adelges tsugae Annand). Changes in foliar terpenes and phenolics were evaluated in new (current year growth) and mature (1-year old growth) hemlock needles during the growing season and into plant dormancy. From April through September, foliar concentrations of non-volatile soluble phenolics, condensed tannins, lignin, mono- and sesquiterpenes α-pinene, camphene, isobornyl acetate, and diterpene resin were quantified. After September, additional analyses of metabolites that continued to differ significantly in new versus mature foliage were carried out. Total soluble phenolic …

Datana Drexelii (Lepidoptera: Notododontidae) Occurrence And Larval Survival On Highbush Blueberry Cultivars, Alex K. Baranowski, Steven R. Alm, Evan L. Preisser

Biological Sciences Faculty Publications

Plant genotype influences plant suitability to herbivores; domesticated plants selected for properties such as high fruit yield may be particularly vulnerable to herbivory. Cultivated strains of highbush blueberry, Vaccinium corymbosum L. can be high-quality hosts for larvae of the gregariously-feeding notodontid Datana drexelii (Hy. Edwards). We conducted an experiment assessing D. drexelii larval survival and pupal weight when fed foliage from five blueberry cultivars: ‘Bluecrop’, ‘Bluetta’, ‘Blueray’, ‘Lateblue’, and ‘Jersey’. We complemented this experimental work with repeated bush-level surveys of a managed blueberry patch for naturally occurring D. drexelii larval clusters. Larval survival and pupal weight were significantly higher on …

Environmentally-Induced Parental Or Developmental Conditioning Influences Coral Offspring Ecological Performance, Hollie M. Putnam, Raphael Ritson-Williams, Jolly Ann Cruz, Jennifer M. Davidson, Ruth D. Gates

Biological Sciences Faculty Publications

The persistence of reef building corals is threatened by human-induced environmental change. Maintaining coral reefs into the future requires not only the survival of adults, but also the influx of recruits to promote genetic diversity and retain cover following adult mortality. Few studies examine the linkages among multiple life stages of corals, despite a growing knowledge of carryover effects in other systems. We provide a novel test of coral parental conditioning to ocean acidification (OA) and tracking of offspring for 6 months post-release to better understand parental or developmental priming impacts on the processes of offspring recruitment and growth. Coral …