Digital Commons Network^™

Inferior St-Elevation Myocardial Infarction Presenting When Urgent Primary Percutaneous Coronary Intervention Is Unavailable: Should We Adhere To Current Guidelines?, Yochai Birnbaum, Glenn N Levine, John French, Juan Carlos Kaski, Dan Atar, Mahboob Alam, David Hasdai, Hani Jneid, Barry F Uretsky

Faculty, Staff and Students Publications

The pivotal studies that led to the recommendations for emergent reperfusion therapy for ST-elevation myocardial infarction (STEMI) were conducted for the most part over 25 years ago. At that time, contemporary standard treatments including aspirin, statin, and even anticoagulation were not commonly used. The 2013 American College of Cardiology Foundation (ACCF)/American Heart Association (AHA) guidelines and the 2017 European Society of Cardiology guidelines give a class I recommendation (with the level of evidence A) for primary percutaneous coronary intervention (pPCI) in patients with STEMI and ischemic symptoms of less than 12 h. However, if the patient presents to a hospital …

Characterization Of Genetic Sources Associated With Restorability And Seed Dimension In Arkansas Restorer Rice Lines, Ozgur Azapoglu

Graduate Theses and Dissertations

Hybrid rice (Oryza sativa L.) breeding offers a significant opportunity to enhance rice production, and the cultivation of a male sterile line is the most important factor in the success of cross-breeding. One of the key elements of hybrid rice production is to develop a restorer line that is assigned as the male parent. The restorer lines provide viable pollen for fertilization of the male sterile plant due to the presence of a restorer gene (Rf) in their genomes. Any superior restorer line applied to hybrid rice production must contain genes/quantitative trait loci (QTL) associated with the desirable agronomic traits …

A Mixed-Methods Analysis Of Biofuels, Teresa Cristina Garcia

Graduate Theses and Dissertations

Brazil has the largest sugarcane acreage in the world (FAOSTAT, 2020) and is the world leader in the production of sugarcane-based ethanol (Sousa Junior et al., 2017). Due to the technical experience in the production of biofuels and the availability of sugarcane straw and bagasse, the country has a great potential to commercially produce second-generation ethanol (E2G) (Nyko et. al., 2010). In 2017, Brazil enacted a new National Biofuels Policy, called RenovaBio, to expand the production and use of biofuels in the country. This dissertation combines three essays that explore biofuels law and policy with a special focus on Brazil. …

Effect Of Feed Additives And Toxic Elements On Swine Growth Performance, Nutrient Digestibility, Immune Function And Reproductive Performance, Richard A. Mudarra Hernández

Graduate Theses and Dissertations

To evaluate the effects of peptide in combination of zinc oxide (Zno) or acidifiers (Exp 1), and gossypol (G) from cottonseed meal (CSM) ( Exp 2&3) on growth performance, complete blood cell counts (Exp 1, 2&3), nutrient digestibility (Exp 1), plasma gossypol (Exp 2&3) and semen quality (Exp 3), weaned pigs (Exp 1), growing gilts (Exp 2) and growing boars (Exp 3) were randomly allotted to dietary treatments. Treatments for Exp 1 during phase 1&2 were: (1) Positive Control (PC), formulated to meet NRC (2012) nutrient requirements; (2) Negative control (NC), fish meal was reduced to achieve -0.13% SID lysine; …

Multiphoton Microscopy And Deep Learning Neural Networks For The Automated Quantification Of In Vivo, Label-Free Optical Biomarkers Of Skin Wound Healing, Jake D. Jones

Graduate Theses and Dissertations

Non-healing ulcerative wounds that occur frequently in diseases such as diabetes are challenging to diagnose and treat due to numerous possible etiologies and the variable efficacy of wound care products. With advanced age, skin wound healing is often delayed, leaving elderly patients at high risk for developing these chronic injuries. As it is challenging to discriminate age-related delays from disease-related chronicity, there is a critical need to develop new quantitative biomarkers that are sensitive to wound status. Multiphoton microscopy (MPM) techniques are well-suited for 3D imaging of epithelia and are capable of non-invasively detecting metabolic cofactors (NADH and FAD) without …

Neogene And Quaternary Events Shaped Diversification And Speciation In Bhutanese Rheophilic Fishes Of The Family Nemacheilidae (Cypriniformes) And Sisoridae (Siluriformes), Karma Wangchuk

Graduate Theses and Dissertations

Biogeography of the Himalayan region [to include the Qinghai-Tibetan Plateau (QTP)] evolved over a ~30M year span, catalyzed by the collision of the Indian and Eurasian plates. The resulting uplift produced major ecological and climatic effects, that in turn drove the diversification of biodiversity. As a result, the QTP is designated as a global biodiversity hotspot particularly vulnerable to cumulative climatic effects, including shrinking distributions, declining numbers, and local extinctions. Understanding how the biodiversity within the Himalaya/ QTP was established and maintained is a necessary first step in prioritizing conservation efforts.

Fishes in global montane regions, such as the Himalaya, …

Legislating Social Inclusion: Social Interaction And Perceptions Of Middle Level Students Toward Those With Disabilities, Deidre Necol Whitehead

Graduate Theses and Dissertations

Recognition of the need for students with disabilities to receive free and appropriate education was brought to the forefront with the passage of Public Law 93 – 112, Rehabilitation Act in 1973. In 1975 Public Law 94-142, the Education for All Handicapped Children Act was enacted requiring all schools to develop and provide a free, appropriate public education for all children and youth with disabilities in the regular classroom to ensure an appropriate education. However, mandating inclusion in classrooms does not ensure social interaction, which is an integral part of learning, especially for early adolescents.

This dissertation uses the Chedoke-McMaster …

Projecting Water Available For Irrigation Use And Identifying Water Supply Stress Under Climate Change Scenarios In Selected U.S. Fruit And Vegetable Production Regions, Andrew Shaw

Graduate Theses and Dissertations

Climate change affects water resources differently across geospatial regions in the United States (U.S). There is a concern of how water availability will be affected by changes in long-term temperature and precipitation patterns, specifically in major production regions for eight fruit and vegetable crops. The effects on surface water available for irrigation use and supply stress in five regions containing 31 Agricultural Statistics Districts (ASDs) were assessed. The Water Supply Stress Index Model was used and modified to project water available for irrigation use across nine climate scenarios driven by historical data, five General Circulation Models, two population scenarios, and …

Biogeography Of The Bovine Respiratory Microbiome And Its Relationship With Bovine Respiratory Disease, Jianmin Chai

Graduate Theses and Dissertations

Bovine respiratory disease (BRD) is the most common and costly disease in the beef cattle industry, leading to high morbidity, mortality and huge economic loss. Despite the recent advances in vaccination and antimicrobial techniques, no significant health-improved outcomes have developed. Due to a deep investigation of the microbiome, respiratory microbiotas are known to have important roles for host health and disease. However, BRD specific pathogens have not yet been identified since they are found in both healthy and diseased animals. A systemic and comprehensive study of the biogeography of the bovine respiratory microbiome and its relationship with BRD is lacking …

Differentially Expressed Genes And Their Clinical Significance In Ischaemic Stroke: An In-Silico Study, Muni Rubens

All Publications

No abstract provided.

Assessment Of Factors Influencing Migratory Landbird Use Of Forested Stopover Sites Along The Delmarva Peninsula During Autumn Migration, J. Andrew Arnold

Biological Sciences Theses & Dissertations

Autumn migration is a time when billions of birds move from breeding grounds in North America to wintering grounds in Central and South America, with many individuals relying on stopover habitats en route for resting and refueling purposes. These stopover sites are critical to the survival of the hundreds of species of migratory landbirds that migrate annually, and thus identifying important stopover sites is a high priority for conserving such taxa. The Delmarva Peninsula; a coastal region of Delaware, Maryland, and Virginia along the mid-Atlantic flyway; consists of forested habitats with ample food and shelter that likely serves as quality …

An Examination Of The Relationship Among Social Services Support, Race, Ethnicity And Recidivism In Justice Involved Mothers, Ne’Shaun Janay Borden

Counseling & Human Services Theses & Dissertations

Historically, women have been ignored and minimized in criminology research and theory, leading to gaps in the literature on justice involved women. In recent years, there has been more focus on women as their rates of involvement in the justice system have increased. Previous studies have found that pathways to justice involvement are different for women and men, with women experiencing higher rates of victimization, sexual abuse and mental health concerns. Further, justice involved women are unique in that over 80% are mothers or primary caregivers for minors. General Strain Theory is used to assert that receiving support should reduce …

An Analysis Of The Effect Of Digital Badging On Workplace Self-Directed E-Learners' Achievement, Persistence, And Self-Regulation, Emma Awuor Agola

STEMPS Theses & Dissertations

Despite the advantages and increase in popularity of self-directed e-learning, this mode of learning is still reported to suffer from low voluntary enrollment rates, high learner dropout rates, as well as low retention of learning. Although there is a paucity of motivation research with regard to self-directed e-learning, a considerable number of studies identify shortfalls in factors related to learner motivation as the most prevalent factor contributing to these pitfalls.

The current study investigated the effect of digital badges, an extrinsic reward, on learning effectiveness, persistence and self-regulation in a corporate self-directed e-learning environment. The study employed an experimental between-subjects …

Drag Incorporated: The Homonormative Brand Culture Of Rupaul's Drag Race, Nathan T. Workman

Institute for the Humanities Theses

This thesis argues RuPaul’s Drag Race (RPDR, 2009–) positions itself as a homonormative pathway to LGBTQ+ social inclusion through privileging neoliberal selfbranding and commodity activist practices that reify privileged raced, classed, and sexuality identity markers. Utilizing interdisciplinary and intersectional cultural studies methods to conduct a textual analysis, I examine how RPDR produces homonormative LGBTQ+ identities through the commodification and standardization of drag cultures. In conversation with existing RPDR scholars, I critically survey RPDR’s gender biases and prosocial messaging as an example of brand culture’s reification of hegemony and homonormativity within LGBTQ+ communities. This research considers the …

A Meta-Analysis Of Group Treatment Outcomes For Veterans With Substance Use Disorders, Robert “Tony” Dice

Counseling & Human Services Theses & Dissertations

Group therapy is commonly used in the treatment of substance use disorders (SUD). Many studies exist related to the efficacy of group interventions for veterans with SUDs. A meta-analysis and systematic review of the literature addressing the use of group therapy, specifically psychoeducational groups, cognitive behavioral therapy (CBT) groups and support groups, in the treatment of SUDs with veterans was conducted. The following questions guided the research: What are viable treatment outcomes for psychoeducational, CBT, and support groups of veterans with SUDs? and What are the measures that capture outcomes related to psychoeducational, CBT, and support groups of veterans with …

A Systemic Review And Meta-Analysis Of Psychoeducational Groups For The Treatment Of Psychopathology Resulting From Child Sexual Abuse, Alexis Lynnette Wilkerson

Counseling & Human Services Theses & Dissertations

It is estimated that 16% of men and 26% of women have experienced child sexual abuse (CSA), and studies have shown a strong association with long-term psychosocial consequences. The use of psychoeducational groups with survivors of CSA has been found to produce favorable outcomes; however, no meta-analyses have been conducted on studies assessing the use of psychoeducational groups to treat victims of CSA. The purpose of this systematic review and random-effect meta-analysis was to examine the efficacy of psychoeducational groups for the treatment of psychopathology subsequent to child sexual abuse (CSA) by addressing the following research questions (1) Are psychoeducational …

A Multiple Case Study Investigating Principles Of Design And Implementation Of Operational Safety Plans For Crises At Colleges, Universities, And Affiliated Institutions, Antonio Passaro, Jr.

Educational Leadership & Workforce Development Theses & Dissertations

In the wake of the 2007 Virginia Tech tragedy, the Virginia state legislature mandated that all college-affiliated institutions create an operational safety plan for natural and manmade crises. Previous empirical research has mostly focused on documenting faculty and students’ perceptions of campus safety, preparations for manmade crises over natural disasters, and enhancing specific aspects of emergency responses for future incidents. Thus, design and implementation “best practices” for higher education operational safety plan protocols is an understudied, yet burgeoning area of inquiry. To address this literature gap, a comparative case study of five institutions was conducted using a novel document analysis …

In The Margins: Reconsidering The Range And Contribution Of Diazotrophs In Nearshore Environments, Corday R. Selden

OES Theses and Dissertations

Dinitrogen (N₂) fixation enables primary production and, consequently, carbon dioxide drawdown in nitrogen (N) limited marine systems, exerting a powerful influence over the coupled carbon and N cycles. Our understanding of the environmental factors regulating its distribution and magnitude are largely based on the range and sensitivity of one genus, Trichodesmium. However, recent work suggests that the niche preferences of distinct diazotrophic (N₂ fixing) clades differ due to their metabolic and ecological diversity, hampering efforts to close the N budget and model N₂ fixation accurately. Here, I explore the range of N₂ fixation …

Constraining Respired Carbon Storage In The Eastern Tropical Pacific Over The Last 25 Thousand Years Using Benthic Foraminiferal Boron/Calcium Ratios, Brian James Close

OES Theses and Dissertations

The storage of inorganic carbon in the deep Pacific Ocean is thought to play an important role in regulating both glacial-interglacial and millennial-scale atmospheric CO₂ concentrations (Broecker and Barker 2007; Sigman et al., 2010). A recent study by Loveley et al. (2017) showed that sedimentary authigenic uranium (aU) concentrations, a proxy for suboxic bottom-water conditions, increased significantly in the Eastern Equatorial Pacific (EEP) during the Last Glacial Maximum (LGM, 18 kyr – 23 kyr). If this is correct, the low-oxygen, CO_2-rich waters would also have a lower pH and a lower carbonate ion concentration ([CO₃^{2- …}

Holy Stitches Batman, Or, Performative Villainy In Gothic/Am, A. Luxx Mishou

English Theses & Dissertations

Holy Stitches, Batman, or, Performative Villainy in Gothic/am is an interdisciplinary examination of gothic affect and deviant fashion in the narrative construction of villainy. It asks not just what a villain looks like, but what it means to look like a villain. A villain is a character who consciously and purposefully deviates from standards of normativity in order to pursue their own, often criminal, interests. The signifier of “villain” articulates a different purpose – an adversarial relationship with normativity that guides personal identification. Not exceptional to a gendered cultural system, they are informed by the societies in which they operate, …

Copper And Cobalt Metal Conjugation Enhances Flaviviral Replication, And Denv/Zikv Caused Thrombocytopenia Suppresses Integrin Signaling, Shovan Dutta

Biomedical Sciences Theses & Dissertations

Vector control is a global concern, and effective strategies have been on the way. Among the many different strategies, insect repellents to protect us from blood-feeding arthropods are very common. Food processing or preservatives in food expose us to several chemicals associated with insect repellents, insecticides, and pesticides. Using metallic conjugation with plant extracts or essential oils has become a widespread strategy to increase their efficacy. But it is worth it to be aware that some of those metallic compounds like Cobalt or Copper upon conjugation with thiosemicarbazone ligands derived from Citral and 2-acetylethiazole at the center coordination enhance both …

Synthesis, Characterization, And Kinetics Studies Of New Cobalt Complexes For The Production Of H2 In Acidic Media, Michael John Celestine

Chemistry & Biochemistry Theses & Dissertations

The kinetics and mechanism of the oxidation of [Co(dmgBF₂)₂(OH₂)₂] (where dmgBF₂ = difluoroboryldimethylglyoximato) by sodium hypochlorite (NaOCl), sodium bromate (NaBrO₃), and bromine (Br₂₎ was investigated by stopped-flow spectrophotometry at 450 nm over a wide temperature range. The pK_a1 value for [Co(dmgBF₂)₂(OH₂)₂] was calculated as 5.27 ± 0.14 at I = 0.60 (NaCl). From the variation in pH studies, the activation parameters were derived from the proposed mechanisms for NaOCl, ΔH_1*, ΔH_2*, ΔS_1*, and …

Improving Collaborations Between Empiricists And Modelers To Advance Grassland Community Dynamics In Ecosystem Models, Kevin R. Wilcox, Kimberly J. Komatsu, Meghan L. Avolio, Nathan P. Lemoine

Biological Sciences Faculty Research and Publications

No abstract provided.

The Response Of Lianas To 20 Yr Of Nutrient Addition In A Panamanian Forest, Stefan A. Schnitzer, Sergio Estrada Villegas, S. Joseph Wright

Biological Sciences Faculty Research and Publications

Over the past two decades, liana density and basal area have been increasing in many tropical forests, which has profound consequences for forest diversity and functioning. One hypothesis to explain increasing lianas is elevated nutrient deposition in tropical forests resulting from fossil fuels, agricultural fertilizer, and biomass burning. We tested this hypothesis by surveying all lianas ≥1 cm in diameter (n = 3,967) in 32 plots in a fully factorial nitrogen (N), phosphorus (P), and potassium (K) addition experiment in a mature tropical forest in central Panama. We conducted the nutrient-addition experiment from 1998 until present and we first …

Lianas Maintain Insectivorous Bird Abundance And Diversity In A Neotropical Forest, Stefan A. Schnitzer, Nicole L. Michel, Jennifer S. Powers, W. Douglas Robinson

Biological Sciences Faculty Research and Publications

The spatial habitat heterogeneity hypothesis posits that habitat complexity increases the abundance and diversity of species. In tropical forests, lianas add substantial habitat heterogeneity and complexity throughout the vertical forest profile, which may maintain animal abundance and diversity. The effects of lianas on tropical animal communities, however, remain poorly understood. We propose that lianas have a positive effect on animals by enhancing habitat complexity. Lianas may have a particularly strong influence on the forest bird community, providing nesting substrate, protection from predators, and nutrition (food). Understory insectivorous birds, which forage for insects that specialize on lianas, may particularly benefit. Alternatively, …

Pre-Veterinary Medicine Advising Tips, Samantha Super

Honors Projects

This document provides tips and recommendations for advisors to better help their pre-veterinary medicine students. After reviewing numerous resources and conducting a survey with GVSU advisors and pre-veterinary students, I identified gaps in knowledge and compiled tips and information about preparing for veterinary school to increase the advisors' knowledge for the benefit of current of future GVSU pre-veterinary students. This document discusses the general path of veterinary school, how to advise students on obtaining experiences, regional and national symposiums that students and advisors can attend, things to consider when preparing for and applying for veterinary schools, specific advice for students …

Regulation Of In Vitro And In Vivo Hepatic Stellate Cell Activation By The Ayrl Hydrocarbon Receptor, Shivakumar Rayavara Veerabhadraiah

Boise State University Theses and Dissertations

Liver fibrosis is a pathological condition characterized by the excessive deposition of extracellular matrix material by activated hepatic stellate cells (HSCs). We recently reported that activation of the aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) increases HSC activation in vitro and in mouse models of experimental liver fibrosis. The goal of this project was to determine the mechanism by which AhR activation impacts HSC activation and the subsequent development of liver fibrosis. It is possible that HSCs are direct cellular targets for TCDD. Alternatively, TCDD could increase HSC activation indirectly by exacerbating hepatocyte damage …

Unsupervised Structural Graph Node Representation Learning, Mikel Joaristi

Boise State University Theses and Dissertations

Unsupervised Graph Representation Learning methods learn a numerical representation of the nodes in a graph. The generated representations encode meaningful information about the nodes' properties, making them a powerful tool for tasks in many areas of study, such as social sciences, biology or communication networks. These methods are particularly interesting because they facilitate the direct use of standard Machine Learning models on graphs. Graph representation learning methods can be divided into two main categories depending on the information they encode, methods preserving the nodes connectivity information, and methods preserving nodes' structural information. Connectivity-based methods focus on encoding relationships between nodes, …

Constitutive Modeling Of Force-Controlled Fatigue Testing In Human Meniscus Tissue, Bradley Scott Henderson

Boise State University Theses and Dissertations

The meniscus is a wedge-shaped fibrocartilaginous tissue located between the femur and tibia that helps stabilize the knee and protect the underlying cartilage. There are 2.5 million reported knee injuries each year, making it the most injured joint in the human body. Nearly twenty percent of these injuries are due to a torn meniscus, leading to over half a million meniscus surgeries performed in the United States annually. Therefore, it is critical to understand the failure modes of meniscus tissue to prevent these debilitating injuries. A failure mode that accounts for one-third of all meniscus injuries is repeated exposure to …

Additive Manufacturing Of Graphene-Based Devices For Flexible Hybrid Electronics, Twinkle Pandhi

Boise State University Theses and Dissertations

In this work, I investigate and enhance the fundamental sensing properties of printed electronic nanomaterials (e.g., graphene) in real-world environments while decreasing weight, cost, and power consumption. The dissertation addresses this issue with the following foci in mind: (1) developing a straightforward and repeatable process to synthesize graphene ink which is also compatible with Inkjet-printing (IJP) and Aerosol Jet printing (AJP). (2) Tuning additive manufacturing printing (IJP and AJP) parameters to establish a repeatable manufacturing process and print high performing (graphene-based) electrodes and interconnects, compatible with the underlying substrate. (3) Investigate power dissipation and electrical breakdown in AJP printed graphene …