Digital Commons Network^™

Access Granted: The Journey Of Conditionally Admitted, First-Generation College Students At An Hbcu, Zackeus Dontrell Johnson

LSU Doctoral Dissertations

This qualitative case study was undertaken to understand the perspectives of first-generation, conditionally-admitted students, regarding how their participation in a college access program may or may not have contributed to their persistence at a Historically Black College and University. This study was grounded in Tinto’s (2012) Model of Institutional Action for Student Success, Schlossberg’s (1990) Transition Theory, and Astin’s (1984) Student Involvement Theory. This single case study was positioned at a university in the South, named Success State University for this research. The study included 5 female participants who participated in virtual interviews due to the unforeseen Coronavirus 2019 outbreak. …

Insulin-Like Growth Factor 2 Mrna-Binding Protein 3 Modulates Aggressiveness Of Ewing Sarcoma By Regulating The Cd164-Cxcr4 Axis, Caterina Mancarella, Giulia Caldoni, Irene Ribolsi, Alessandro Parra, Maria Cristina Manara, Arthur M Mercurio, Andrea Morrione, Katia Scotlandi

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Ewing sarcoma (EWS) is the second most common bone and soft tissue-associated malignancy in children and young adults. It is driven by the fusion oncogene EWS/FLI1 and characterized by rapid growth and early metastasis. We have previously discovered that the mRNA binding protein IGF2BP3 constitutes an important biomarker for EWS as high expression of IGF2BP3 in primary tumors predicts poor prognosis of EWS patients. We additionally demonstrated that IGF2BP3 enhances anchorage-independent growth and migration of EWS cells suggesting that IGF2BP3 might work as molecular driver and predictor of EWS progression. The aim of this study was to further define the …

Isotype-Specific Outcomes In Fc Gamma Receptor Targeting Of Pspa Using Fusion Proteins As A Vaccination Strategy Against Streptococcus Pneumoniae Infection, Kari Wiedinger

Seton Hall University Dissertations and Theses (ETDs)

Streptococcus pneumoniae (Spn) remains a considerable threat to public health despite the availability of antibiotics and polysaccharide conjugate vaccines. The lack of mucosal immunity in addition to capsular polysaccharide diversity, has proved to be problematic in developing a universal vaccine against Spn. Targeting antigen to Fc receptors is an attractive way to augment both innate and adaptive immunity against mucosal pathogens, by promoting interactions with activating Fcγ receptors (FcγR) that mediate diverse immunomodulatory functions. The effect of targeting FcγR is highly influenced by the IgG subclass, which bares differential affinities for activating and inhibitory FcγR. In the current study we …

High-Resolution Mapping Of Fish Conservation Priorities Within The Mobile River Basin, James R. Carl

Master of Science in Integrative Biology Theses

Identifying potential protected areas is increasingly important as freshwater fishes and associated aquatic organisms are under increasing peril. Human population, growth and subsequent landscape alteration, is degrading water quality and changing the physical characteristics of streams, potentially threatening aquatic species. The goal is to assess the capacity for protected areas to maintain diverse stream fish communities within the Mobile River Basin, including the upper Coosa River basin, by overlaying projections of fish species distributions and footprints of protected areas. Tools for identifying fish species distributions, environmental predictors, and potential protected areas include spatial conservation prioritization algorithms combined with open access …

Morphological Evidence For An Oral Venom System In Caecilian Amphibians, Pedro Luiz Mailho-Fontana, Marta Maria Antoniazzi, Cesar Alexandre, Daniel Carvalho Pimenta, Juliana Mozer Sciani, Edmund D. Brodie Jr., Carlos Jared

Biology Faculty Publications

Amphibians are known for their skin rich in glands containing toxins employed in passive chemical defense against predators, different from, for example, snakes that have active chemical defense, injecting their venom into the prey. Caecilians (Amphibia, Gymnophiona) are snake-shaped animals with fossorial habits, considered one of the least known vertebrate groups. We show here that amphibian caecilians, including species from the basal groups, besides having cutaneous poisonous glands as other amphibians do, possess specific glands at the base of the teeth that produce enzymes commonly found in venoms. Our analysis of the origin of these glands shows that they originate …

Open Access Publishing In The European Union: The Example Of Scientific Works, Nikos Koutras

Research outputs 2014 to 2021

Access to information resources and publicly-funded research outcomes have been considered in Europe during the last decade. Open access practice became part of the European institutions’ agenda since 2006 within the final report of the European Research Advisory Board. The Lisbon Treaty (2007) explicitly confirmed the European Union’s commitment to free circulation of scientific knowledge (Article 179 TFEU) and the dissemination of research results (Article 183 TFEU). In this regard, the Horizon 2020 program illustrates the importance of open access policy towards further dissemination of scientific information. The European Commission also introduced in July 2012 a scientific information package to …

Development Of Pomegranate Extract-Loaded Solid Lipid Nanoparticles: Quality By Design Approach To Screen The Variables Affecting The Quality Attributes And Characterization, Dalia Attia, Noha Badawi, Khalid El-Say, Mohamed El-Nabarawi, Mohamed Elmazar, Mahmoud Teaima

Pharmacy

The aim of this work was to study the influence of process variables on the quality attributes of pomegranate extract loaded solid lipid nanoparticles (PE-SLNs) using Plackett− Burman design. PE-SLN formulations were prepared by hot homogenization followed by ultra-sonication technique and evaluated based on the dependent variables that were analyzed utilizing Statgraphics Centurion XV software. The lipid and surfactant (type and concentration), co-surfactant concentration, sonication time, and amplitude were selected as the independent variables (X1−X7). The dependent parameters were particle size, polydispersity index, zeta potential, entrapment efficiency, and cumulative drug release (Y1−Y5). Response surface plots, Pareto charts, and mathematical equations …

Ecological Characteristics Of Halophytes In The Arid Areas, Wenjun Han, Kunio Hamamura

IGC Proceedings (1977-2023)

No abstract provided.

Response Of Activated Oxygen Metabolism To Water Stress In Different Drought‐Tolerant Alfalfa (Medicago Sativa) At Seedling Stage, Ruihong Han

IGC Proceedings (1977-2023)

No abstract provided.

Effect Of Patch Size Of Metacommunity On Species Diversity In Leymus Chinensis Meadow In The Songnen Plains Of China, Dayong Han, Yunfei Yang, Jiandong Li

IGC Proceedings (1977-2023)

No abstract provided.

The Successional Dynamic Changing Process Of Vegetation Steppe From Central Asia And Mongolian Pasture, Erdenejav Guriin Proffessor

IGC Proceedings (1977-2023)

No abstract provided.

Biological Soil Crust Under Shrubs And Its Topsoil Properties In The Process Of Dune Vegetation Restoration In The Horqin Sandy Grassland, Inner Mongolia, Yirui Guo, Halin Zhao, Xiaoan Zuo

IGC Proceedings (1977-2023)

No abstract provided.

Antibacterial Efficacy Of Novel Eastern Medicine-Inspired Toothpastes Compared To Commercial Formulations, Joshua S. Goldfaden

Pacific Journal of Health

Toothpaste is an oral health care agent that dates back to the 5^th Century B.C. in East Asia. Following the conception of dentistry in the 7^th Century B.C. and the field’s subsequent growth, the embodiment of toothpaste has evolved from containing natural substances such as tea leaves to abrasive chemicals, particularly: fluoride, triclosan, and sodium lauryl sulfate (SLS). Regarding how each respective reagent functions, fluoride forms a complex with calcium ions in the teeth to prevent erosion of the protective enamel coating. This ion also disrupts metabolic activities of Streptococcus mutans (S. mutans), which are the …

Artificial Intelligence Towards Future Industrial Opportunities And Challenges, Gizealew Dagnaw

African Conference on Information Systems and Technology

The industry 4.0 will bring reflective changes to our society, including an important digital shift in the manufacturing sector. At present, several manufacturing firms are trying to adopt the practices of industry 4.0 throughout their supply chain. The Fourth Industrial Revolution and the artificial intelligence at its core are fundamentally changing the way we live, work and interact as citizens. The complexity of this transformation may look overwhelming and to many threatening. Recently, the dramatic growth of new generation information technologies has prompted several countries to seek new strategies for industrial revolution. The globalization and the competitiveness are forcing companies …

The Ai Revolution, Connor Haskins

The E&S Magazine

No abstract provided.

Efficient Data Mining Algorithm Network Intrusion Detection System For Masked Feature Intrusions, Kassahun Admkie, Kassahun Admkie Tekle

African Conference on Information Systems and Technology

Most researches have been conducted to develop models, algorithms and systems to detect intrusions. However, they are not plausible as intruders began to attack systems by masking their features. While researches continued to various techniques to overcome these challenges, little attention was given to use data mining techniques, for development of intrusion detection. Recently there has been much interest in applying data mining to computer network intrusion detection, specifically as intruders began to cheat by masking some detection features to attack systems. This work is an attempt to propose a model that works based on semi-supervised collective classification algorithm. For …

The Comparison Of Photosynthetic Physiological Characteristics Between Leymus Chinensis And Leymus Secalinus In The Songnen Plains, R. Guo, Yunfei Yang

IGC Proceedings (1977-2023)

No abstract provided.

Emphysematous Gastritis: A Complication Of Rare Sarcina Ventriculi Infection, Gerald Cox

Loma Linda University Student Journal

CASE REPORT: A 79-year-old Caucasian man with a history of constipation, uncomplicated umbilical hernia and chronic obstructive pulmonary disease (COPD) requiring 2L 02 via nasal canula at night, presented to the emergency department with increasing shortness of breath of 2 days duration. He was found to be saturating 87% on 5L nasal canula with his remaining vital signs within normal limits. Physical examination revealed mild retractions with wheezing and rhonchi bilaterally, in addition to mild abdominal distention.

Laboratory investigation revealed a hemoglobin of 14.6 g/dL, creatinine of 1.5 mg/dL and blood urea nitrogen of 26 mg/dL. Arterial blood gas …

Evaluating The Effects Of A Brief Assertiveness And Help Seeking Skill Intervention, Madeline S. Blocker

LSU Master's Theses

Children in foster care lead their lives at an increased risk for mental health issues that are often complicated by the unstable and unpredictable nature of their living arrangements and interpersonal relationships. As such, there is substantial need to examine brief therapies and interventions for use with children in foster care and children who have experienced similar trauma and instability. Mental health care providers for children in foster care often may not have sufficient periods of time to implement treatment with fidelity. The present study investigated the efficacy of a summer camp based, brief behavioral intervention targeting help-seeking behavior and …

Researchers Adapt To Telework, Grant Recipients Announced

Jefferson Surgical Solutions

Can pancreatic cancer research continue during a global pandemic? For the Jefferson Pancreas, Biliary and Related Cancer Center within the Department of Surgery, the answer has been a resounding “yes.” Graduate students Samantha Brown and Angelo Montenegro, and Drs. Charles J. Yeo, MD, and Jonathan Brody, PhD, share how Jefferson has made that happen in “Rules for scientific progress while living with the COVID-19 Pandemic: from ‘benchside’ to ‘fireside,’” in Cancer Biology & Therapy.

Here are the four strategies the Jefferson team outlines for navigating the uncertainty without compromising the science.

Strategy #1: Create a plan for essential lab work, …

Monomyth Or Monogamyth? Polyamory’S Conceptual Challenges To The Hero’S Journey, James K. Beggan

Heroism Science

In the context of polyamorous relationships, a unicorn can be defined as a single, bisexual woman interested in forming a relationship with a heterosexual couple. Heroism scholars have suggested that the hero’s journey (or monomyth) can be used as a framework for understanding everyone’s life. By extension, it would be possible to frame the search for a receptive unicorn as a hero’s quest. Unicorn hunters are stigmatized by the general public for challenging the monogamyth, i.e., the monogamy norm. They are also criticized by the polyamorous community for privileging their own interests ahead of those of the women they are …

Office Of Equity And Inclusion Newsletter - July 2020, Office Of Equity And Inclusion, East Tennessee State University

Office of Equity and Inclusion Newsletters

No abstract provided.

Impact Analysis On Distribution Prediction Of Stipa Species Under Climate Change, Xuqing Tang, Jianlin Li

Journal of System Simulation

Abstract: Based on the actual climatic data from 1981 to 2000 in Northeast China, the predicted climatic data and the actual distribution data of Stipa species, 12 climatic factor indicators affecting Stipa species distribution were extracted combining with similar biological and ecological characteristics of Stipa. By introducing Gauss Competitive Exclusion Principle and the statistical analysis method, a competitive stochastic mathematical model of the distribution of Stipa was built, and the corresponding algorithm was given. The forecast figures were obtained for the optimal, medium and general adaptable distribution of the five Stipa species from 2041 to 2050 and from 2091 …

Evidence For The Evolution Of Thermal Tolerance, But Not Desiccation Tolerance, In Response To Hotter, Drier City Conditions In A Cosmopolitan, Terrestrial Isopod, Aaron R. Yilmaz, Sarah E. Diamond, Ryan A. Martin

Faculty Scholarship

Cities are often hotter and drier compared with nearby undeveloped areas, but how organisms respond to these multifarious stressors associated with urban heat islands is largely unknown. Terrestrial isopods are especially susceptible to temperature and aridity stress as they have retained highly permeable gills from their aquatic ancestors. We performed a two temperature common garden experiment with urban and rural populations of the terrestrial isopod, Oniscus asellus, to uncover evidence for plastic and evolutionary responses to urban heat islands. We focused on physiological tolerance traits including tolerance of heat, cold, and desiccation. We also examined body size responses to urban …

Cbl Negatively Regulates Nlrp3 Inflammasome Activation Through Glut1-Dependent Glycolysis Inhibition, Hsin Chung Lin, Yu Jen Chen, Yau Huei Wei, Yu Ting Chuang, Su Heng Hsieh, Jing Yu Hsieh, Yi Lin Hsieh, David M. Ojcius, Kuo Yang Huang, I. Che Chung, Sheng Ning Yuan, Yu Sun Chang, Lih Chyang Chen

All Dugoni School of Dentistry Faculty Articles

Activation of the nod-like receptor 3 (NLRP3) inflammasomes is crucial for immune defense, but improper and excessive activation causes inflammatory diseases. We previously reported that Cbl plays a pivotal role in suppressing NLRP3 inflammasome activation by inhibiting Pyk2-mediated apoptosis-associated speck-like protein containing a CARD (ASC) oligomerization. Here, we showed that Cbl dampened NLRP3 inflammasome activation by inhibiting glycolysis, as demonstrated with Cbl knockout cells and treatment with the Cbl inhibitor hydrocotarnine. We revealed that the inhibition of Cbl promoted caspase-1 cleavage and interleukin (IL)-1β secretion through a glycolysis-dependent mechanism. Inhibiting Cbl increased cellular glucose uptake, glycolytic capacity, and mitochondrial oxidative …

Raman Spectroscopy Characterization Extracellular Vesicles From Bovine Placenta And Peripheral Blood Mononuclear Cells, Han Zhang, Ana Caroline Silva, Wei Zhang, Heloisa M. Rutigliano, Anhong Zhou

Animal, Dairy, and Veterinary Science Faculty Publications

Placenta-derived extracellular vesicles (EVs) are involved in communication between the placenta and maternal immune cells possibly leading to a modulation of maternal T-cell signaling components. The ability to identify EVs in maternal blood may lead to the development of diagnostic and treatment tools for pregnancy complications. The objective of this work was to differentiate EVs from bovine placenta (trophoblast) and peripheral blood mononuclear cells (PBMC) by a label-free, non-invasive Raman spectroscopy technique. Extracellular vesicles were isolated by ultracentrifugation. Dynamic light scattering (DLS) and scanning electron microscopy (SEM) were applied to verify the presence and the size distribution of EVs. Raman …

Using Optimization Methods For Solving Problems In Sustainable Urban Mobility And Conservation Planning, Zulqarnain Haider

USF Tampa Graduate Theses and Dissertations

This dissertation considers three separate optimization problems related to sustainable urban and environmental systems. The first problem relates to the nightly relocation and recharging operations for Free-floating electric vehicle sharing (FFEVS) systems. Such operations involve a crew of drivers to move the shared electric vehicles (EVs), and a fleet of shuttles to transport those drivers. Mixed integer programs are used to model the relocation and recharging operations. Two approaches are devised: sequential and synchronized approaches. In the sequential approach, the movement of EVs is first decided, then the routing of shuttles and drivers is determined. In the synchronized approach, all …

Changing The Culture Of Consent: Teaching Young Children Personal Boundaries, Marlesha C. Bell

USF Tampa Graduate Theses and Dissertations

Currently, eight states and Washington D.C. mention consent education in their sex education standards (Naide, 2020). Most school-based consent education curricula focus on teaching pre-teens through adults consent within the context of sexual contact (Planned Parenthood, 2016). However, consent may be relevant for behavior outside the context of sexual contact. Young children could develop a repertoire for consent skills and use it to set and respect boundaries. Furthermore, behavior analysis has teaching technologies that could be used to inform a curriculum for teaching consent, such as behavioral skills training (Johnson et al., 2006) and video modeling (Charlop & Milstein, 1989). …

A Comparative Study Of Sleep And Diurnal Patterns In House Mouse (Mus Musculus) And Spiny Mouse (Acomys Cahirinus), Chanung Wang, Lauren E. Guerriero, Dillon M. Huffman, Asma'a A. Ajwad, Trae C. Brooks, Sridhar Sunderam, Ashley W. Seifert, Bruce F. O'Hara

Biomedical Engineering Faculty Publications

Most published sleep studies use three species: human, house mouse, or Norway rat. The degree to which data from these species captures variability in mammalian sleep remains unclear. To gain insight into mammalian sleep diversity, we examined sleep architecture in the spiny basal murid rodent Acomys cahirinus. First, we used a piezoelectric system validated for Mus musculus to monitor sleep in both species. We also included wild M. musculus to control for alterations generated by laboratory-reared conditions for M. musculus. Using this comparative framework, we found that A. cahirinus, lab M. musculus, and wild M. musculus were …

Exploring Associations Between Susceptibility To The Use Of Electronic Nicotine Delivery Systems And E-Cigarette Use Among School-Going Adolescents In Rural Appalachia, Hadii M. Mamudu, Christen Nwabueze, Florence M. Weierbach, Joshua Yang, Antwan Jones, Michelle Mcnabb, Esther Adeniran, Ying Liu, Liang Wang, Cynthia J. Blair, Adeola Awujoola, David L. Wood

ETSU Faculty Works

Electronic nicotine delivery systems (ENDS) use, including e-cigarettes, has surpassed the use of conventional tobacco products. Emerging research suggests that susceptibility to e-cigarette use is associated with actual use among adolescents. However, few studies exist involving adolescents in high-risk, rural, socioeconomically distressed environments. This study examines susceptibility to and subsequent usage in school-going adolescents in a rural distressed county in Appalachian Tennessee using data from an online survey (N = 399). Relying on bivariate analyses and logistic regression, this study finds that while 30.6% of adolescents are ever e-cigarette users, 15.5% are current users. Approximately one in three adolescents are …