Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Social and Behavioral Sciences (9522)
- Education (5391)
- Medicine and Health Sciences (4669)
- Psychology (4131)
- Arts and Humanities (3576)
-
- Law (2021)
- Business (1665)
- Sociology (1483)
- Higher Education (1161)
- Public Health (1087)
- Life Sciences (1085)
- Nursing (890)
- Physical Sciences and Mathematics (881)
- Communication (825)
- Public Affairs, Public Policy and Public Administration (800)
- Teacher Education and Professional Development (709)
- Curriculum and Instruction (666)
- Medical Specialties (648)
- Religion (614)
- Clinical Psychology (607)
- Educational Assessment, Evaluation, and Research (579)
- Educational Leadership (579)
- Social Work (575)
- Mental and Social Health (574)
- Library and Information Science (562)
- Educational Administration and Supervision (554)
- Engineering (527)
- Counseling (515)
- Political Science (501)
- History (489)
- Institution
-
- Walden University (1149)
- University of Nebraska - Lincoln (628)
- City University of New York (CUNY) (543)
- Brigham Young University (465)
- San Jose State University (433)
-
- Association of Arab Universities (428)
- Nova Southeastern University (397)
- University of Mississippi (390)
- Liberty University (378)
- Sigma Theta Tau International Honor Society of Nursing (369)
- Chulalongkorn University (343)
- University of Plymouth (336)
- University of South Florida (318)
- Utah State University (315)
- University of Central Florida (314)
- Portland State University (309)
- Virginia Commonwealth University (302)
- University of Nevada, Las Vegas (294)
- Edith Cowan University (290)
- Georgia Southern University (285)
- University of South Carolina (279)
- University of Kentucky (274)
- Singapore Management University (262)
- Old Dominion University (244)
- Louisiana State University (238)
- Western Michigan University (236)
- Universitas Indonesia (231)
- California State University, San Bernardino (219)
- University of New Mexico (219)
- East Tennessee State University (211)
- Keyword
-
- COVID-19 (438)
- Education (376)
- Psychology (343)
- Mental health (310)
- Depression (290)
-
- Gender (247)
- Leadership (247)
- Stress (236)
- Higher education (219)
- Anxiety (212)
- Trauma (205)
- Children (195)
- Resilience (165)
- Women (162)
- Social media (159)
- Mindfulness (157)
- Motivation (153)
- Coronavirus (151)
- Communication (140)
- Culture (136)
- Self-efficacy (134)
- Identity (130)
- Adolescents (128)
- Ethics (121)
- Undergraduate (120)
- Burnout (117)
- Mental Health (117)
- Students (114)
- Technology (113)
- Race (112)
- Publication
-
- Theses and Dissertations (1110)
- Walden Dissertations and Doctoral Studies (1058)
- Dissertations (637)
- Electronic Theses and Dissertations (422)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (328)
-
- Faculty Publications (321)
- Doctoral Dissertations and Projects (277)
- Library Philosophy and Practice (e-journal) (261)
- Honors Theses (222)
- Dissertations, Theses, and Capstone Projects (199)
- Research outputs 2014 to 2021 (194)
- An-Najah University Journal for Research - B (Humanities) (193)
- USF Tampa Graduate Theses and Dissertations (190)
- Publications and Research (173)
- Theses (167)
- Masters Theses (166)
- Faculty Scholarship (159)
- The Qualitative Report (155)
- Master's Theses (139)
- Electronic Theses and Dissertations, 2020-2023 (138)
- Expressive Therapies Capstone Theses (135)
- Open Access Publications (131)
- Articles (123)
- Psychology Faculty Publications (120)
- Electronic Theses and Dissertations Archive (111)
- Electronic Theses, Projects, and Dissertations (111)
- Doctoral Dissertations (108)
- Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan (107)
- Capstone Projects and Master's Theses (96)
- Graduate Theses and Dissertations (94)
- Publication Type
Articles 1411 - 1440 of 30591
Full-Text Articles in Entire DC Network
Tracing Relations Between Attachment, Social Media Use, Self-Esteem, Loneliness, And Depression: A Mediation Model, Meagan Patricia Sabo
Tracing Relations Between Attachment, Social Media Use, Self-Esteem, Loneliness, And Depression: A Mediation Model, Meagan Patricia Sabo
Masters Theses
An extensive amount of correlational research has well-established the link between insecure attachment style and subsequent adverse interpersonal and psychopathological outcomes. Moreover, the rise of social media has precipitated a shift in the methods by which individuals communicate; consequently, this has resulted in the shifting of preexisting dispositions toward dysfunctional behaviors to a more ubiquitous route of manifestation. Given that attachment literature has indicated notable differences in both underlying mechanisms and resulting outcomes of both avoidant and anxious attachment, examination of this alongside social media use provides valuable insight into potential relationships between the two. Further, research has examined the …
Creating A Music Education Curriculum Based On Current Teaching Strategies, Stanley K. Holloway
Creating A Music Education Curriculum Based On Current Teaching Strategies, Stanley K. Holloway
Masters Theses
Contemporary pedagogical, psychological and sociological researches highlight the need for music education available to every child. Starting from the fundamental point of view according to which music affects the development of the child's whole personality, this idea stands out in history since the 17th century. Various educators in the late nineteenth and early twentieth century emphasized the importance of music education for every child. To nurture a child’s music development, as it is to support the development requires other basic skills in the child’s life. Young children learn most basic life skills from their parents because adults create consciously and …
Disservice: Disabled Library Staff And Service Expectations, Kelsey George
Disservice: Disabled Library Staff And Service Expectations, Kelsey George
Library Faculty Research
No abstract provided.
Global Health At The Local Level: Innovative Approaches For Preventing Hiv/Aids Among Adolescent Girls In Botswana With Evidence From An Evaluation Study On Perceptions Of Cross Generational Sex And Edu-Tainment Strategies, Rebecca L. Upton
Sociology & Anthropology Faculty publications
In Botswana, cross-generational sex (CGS) accounts for a disparity in incidence and prevalence rates of HIV infection between young men and women in the country. Ministry of Health quantitative data and ethnographic research indicate that almost one third of college-aged girls in urban cities had high-risk sex with a partner over ten years older in the past year. Described as “Mma 14s” (in the past this was often translated as “mothers at age 14” or “women at 14”) these girls are caught between cultural imperatives that emphasize the “traditional” and global consumption and goals of being a “modern” person. Rates …
Medicine And Surgery Residents' Perspectives On The Impact Of Covid-19 On Graduate Medical Education., Tanvi Rana, Christopher Hackett, Timothy Quezada, Abhishek Chaturvedi, Veli Bakalov, Jody Leonardo, Sandeep Rana
Medicine And Surgery Residents' Perspectives On The Impact Of Covid-19 On Graduate Medical Education., Tanvi Rana, Christopher Hackett, Timothy Quezada, Abhishek Chaturvedi, Veli Bakalov, Jody Leonardo, Sandeep Rana
COVID-19 Papers, Posters, and Presentations
The COVID-19 crisis has had an unprecedented impact on resident education and well-being: social distancing guidelines have limited patient volumes and forced virtual learning, while personal protective equipment (PPE) shortages, school/daycare closures, and visa restrictions have served as additional stressors. Our study aimed to analyze the effects of COVID-19 crisis-related stressors on residents' professional and personal lives. In April 2020, we administered a survey to residents at a large academic hospital system in order to assess the impact of the pandemic on residency training after >6 weeks of a modified schedule. The primary outcome was to determine which factors or …
Improving Suicide Screening And Safety Plan Documentation Rates In Behavioral Health Clinics, Brandi Hrasdzira
Improving Suicide Screening And Safety Plan Documentation Rates In Behavioral Health Clinics, Brandi Hrasdzira
Doctor of Nursing Practice
Suicide is the 10th leading cause of death in the United States with over 47,000 people dying in 2017 from suicide alone (NIMH, 2019). In the United States, one in three people who die by suicide were seen by a behavioral health provider within the same year (McCabe et al., 2018). The purpose of this project was to determine if suicide screenings and safety plans are being completed and documented properly; how many patients are refusing to complete the patient health questionnaire (PHQ-9) and is there a pattern present in these patients. Objectives are to improve the rates of suicide …
Implementation Of A Guideline For Major Depressive Disorder In A Private Practice Clinic, Doreen Phillips
Implementation Of A Guideline For Major Depressive Disorder In A Private Practice Clinic, Doreen Phillips
Doctor of Nursing Practice
Major depressive disorder (MDD) is a chief mental health illness that carries a profound economic burden. Many who suffer from MDD find little to no relief with traditional pharmacological interventions.The 2010 American Psychiatric Association Guidelines for Treatment of Patients with MDD recognized TMS as a second-line treatment choice. Several double-blind, randomized controlled trials illustrated the efficacy and safety of TMS as a viable treatment option for MDD. The purpose of this project was to implement standardized processes through the use of a treatment guideline to help provide comprehensive treatment options for patients suffering from moderate to severe major depressive disorder …
Increasing Adherence To Measurement-Based Depression Management In Primary Care, Renad Saadat
Increasing Adherence To Measurement-Based Depression Management In Primary Care, Renad Saadat
Doctor of Nursing Practice
Background and Review of Literature. Approximately 11 million Americans 18 years or older experienced a severe symptom of depression leading to impairment in 2017. The severity of depressive symptoms is often miscalculated in primary care as measurement-based tools for the diagnosis and ongoing reassessment varies. Purpose. The purpose of the project was to increase provider adherence in using the patient health questionnaire-9 (PHQ-9) for ongoing evaluation of the severity of depressive symptoms in patients with depression at a primary care clinic in San Antonio, Texas. Objectives. The main objective of this Doctor of Nursing Practice project is …
Blackness As Fighting Words, Etienne C. Toussaint
Blackness As Fighting Words, Etienne C. Toussaint
Faculty Publications
The resurgence of worldwide protests by activists of the Movement for Black Lives (BLM) has ushered a global reckoning with the meaning of this generation’s rallying cry – “Black Lives Matter.” As citizens emblazon their streets with this expression in massive artistic murals, the Trump administration has responded with the militarized policing of non-violent public demonstrations, revealing not merely a disregard for public safety, but far worse, a concerted dismantling of protestors’ First Amendment rights. Nevertheless, BLM protests have persisted. Accordingly, this Essay considers the implications of this generation’s acclamation of Black humanity amidst the social tensions exposed during the …
Burden Of Care As Perceived By Informal Caregivers Of The Patients Receiving Chemotherapy In Tertiary Care Hospital Of Karachi, Pakistan, Asher Ghori, Rubina Barolia, Naghma Rizvi, Ghulam Qadir
Burden Of Care As Perceived By Informal Caregivers Of The Patients Receiving Chemotherapy In Tertiary Care Hospital Of Karachi, Pakistan, Asher Ghori, Rubina Barolia, Naghma Rizvi, Ghulam Qadir
School of Nursing & Midwifery
Background: Almost 32.5 million people are diagnosed with cancer annually. The huge number of cancer patients with deteriorating health renders a far greater number of informal caregivers bearing the burden of care in different forms and magnitude. The main purpose of the study was to explore the types of burden perceived by the informal caregivers and the factors associated with the caregiving burden.
Methods: A quantitative descriptive cross-sectional study design was adopted to answer the research questions from April to May 2016. Around 200 informal caregivers were recruited from one of the tertiary hospitals of Karachi, Pakistan. The modified ZBIS …
The Impact Of A Digital Intervention On Perceived Stress, Resiliency, Social Support, And Intention To Leave Among Newly Licensed Nurses: A Randomized Controlled Trial, Lisa Concilio
Electronic Theses and Dissertations
The nursing shortage has been deemed a public health crisis with the turnover rate of newly licensed nurses (NLNs) growing (Robert Wood Johnson Foundation, 2014). One out of five NLNs are leaving the profession due to work dissatisfaction and feelings of inadequacy (National Academy of Medicine, 2017). NLN attrition during the first year of hire has been associated with feelings of overwhelming stress and decreased sense of support which negatively impact patient safety (Spence Laschinger et al., 2016). As seasoned nurses are attempting to retire amidst a nursing shortage (American Association of Colleges of Nursing, 2018), NLNs require more support …
Trauma Informed E-Newsletter: Issue 3, Jeanne Williamson, Brianca Smith-Austin
Trauma Informed E-Newsletter: Issue 3, Jeanne Williamson, Brianca Smith-Austin
Student Counseling
No abstract provided.
National Coral Reef Management Fellows Newsletter Volume 3 | Issue 2, National Oceanic And Atmospheric Administration (Noaa) Coral Reef Conservation Program
National Coral Reef Management Fellows Newsletter Volume 3 | Issue 2, National Oceanic And Atmospheric Administration (Noaa) Coral Reef Conservation Program
National Coral Reef Management Fellowship Newsletter
No abstract provided.
Shared Service In The Archives: The Johns Hopkins University First-Generation Students Oral History Project, Jennifer Kinniff, Annie Tang
Shared Service In The Archives: The Johns Hopkins University First-Generation Students Oral History Project, Jennifer Kinniff, Annie Tang
Library Books and Book Chapters
"Archivists, like librarians, often provide service to users that is defined by the mission and the institutional context of their employer. University archivists are tasked with documenting the history of their institution, and in doing so, have historically focused much of their attention on the records of institutional offices. This practice leaves out the stories of students and other communities affected by the institution. As immersed as university archivists are in academic libraries and the infrastructure of the academy, activist archivists can still challenge the status quo through intentional collecting of what is neither de facto, nor traditional. As archivists …
Impact Of Need For Cognitive Closure On Framing, Omar Yanouri
Impact Of Need For Cognitive Closure On Framing, Omar Yanouri
McNair Scholars Research Journal
No abstract provided.
Parent Well-Being In Divorce Education, Sharon E. Powell, Sarah Cronin, Ellen Mccann, Jenifer Mcguire, Emily Becher, Eugene Hall
Parent Well-Being In Divorce Education, Sharon E. Powell, Sarah Cronin, Ellen Mccann, Jenifer Mcguire, Emily Becher, Eugene Hall
Journal of Family Strengths
Objective. To describe the role of parent well-being in divorce education and to explore the relationship between parent well-being, coparenting, and child outcomes. Design. Data was analyzed using multiple regression from pre, post, and follow-up surveys from 272 parents who took the Parents Forever divorce education course. Results. Changes in positive and negative coparenting significantly predicted changes in child well-being over time, accounting for 8% of the variance in change in child well-being. Parent-well-being significantly predicted changes in child well-being over and above coparenting and, when entered into the regression model, an additional 7.2% of the variance in changes in …
Applications Of Statistical Methods Studying The Impact Of Mobilization Regimes On The Total Collection Yield Of Hematologic Stem Cell, Mengchen Ding
Applications Of Statistical Methods Studying The Impact Of Mobilization Regimes On The Total Collection Yield Of Hematologic Stem Cell, Mengchen Ding
Dissertations and Theses (Open Access)
Hematologic malignancies are cancers that develop in the blood, bone marrow, and lymph nodes. Hematopoietic stem cell transplantation (HSCT) is a critical therapeutic approach that contributes to offer a potential cure for hematologic cancers and other hematologic disorders by replacing abnormal bone marrow with healthy bone marrow components to help bone marrow function recovery. Peripheral blood is the primary resource for collecting hematopoietic stem cells (HSCs). The collection yield of HSCs is critical for successful transplantation. Few articles have discussed this topic that the collection of stem cells not only from healthy donors but also from donors with a hematologic …
The Comparative Effect Of Automated Reminders/Recalls Interventions On The Appointments Rate Of Adolescent Wellness Care Visit, Biai Dominique Elmir Digbeu
The Comparative Effect Of Automated Reminders/Recalls Interventions On The Appointments Rate Of Adolescent Wellness Care Visit, Biai Dominique Elmir Digbeu
Dissertations and Theses (Open Access)
An Adolescent Wellness Care (AWC) visit is an annual preventive doctor visit predestined to assess the overall health of adolescents aged between 12 and 21 years old. Compared to their younger counterparts, adolescents who are using public insurance are at risk of not completing AWC visits due to several factors related to age or providers disparities in their living environment. This research was a quasiexperimental study aiming to compare two methods of automated Reminders/Recalls (RR) interventions, ‘phone-only’ versus ‘phone-and-text’, in order to evaluate which method is more effective in helping parents/guardians or young adults to schedule an AWC visit. A …
2020-December-01-Going Places, University Marketing And Communication, East Tennessee State University
2020-December-01-Going Places, University Marketing And Communication, East Tennessee State University
ETSU News
Rebecca Fugate is a family-focused solutions counselor with the Center for Community Outreach and Applied Research. She was previously a travel counselor with World Travel Service Inc. She holds an M.A. in psychology-clinical counseling from The Citadel.
Bridget Garland is an assistant HIPAA compliance officer in the Office of HIPAA Compliance and Security after serving ETSU Physicians as EHR director. She holds a master’s degree in English from ETSU.
Brianne A. Hayes is the bursar in Business and Finance after serving as bursar at the University of Memphis. She holds a B.S. degree in accounting from the University of South …
A Graphical Eda Tool With Ggplot2: Brinton, Pere Millán-Martínez, Ramon Oller
A Graphical Eda Tool With Ggplot2: Brinton, Pere Millán-Martínez, Ramon Oller
The R Journal
We present brinton package, which we developed for graphical exploratory data analysis in R. Based on ggplot2, gridExtra and rmarkdown, brinton package introduces wideplot() graphics for exploring the structure of a dataset through a grid of variables and graphic types. It also introduces longplot() graphics, which present the entire catalog of available graphics for representing a particular variable using a grid of graphic types and variations on these types. Finally, it introduces the plotup() function, which complements the previous two functions in that it presents a particular graphic for a specific variable of a dataset. This set of functions is …
Ordinalclust: An R Package To Analyze Ordinal Data, Margot Selosse, Julien Jacques, Christophe Biernacki
Ordinalclust: An R Package To Analyze Ordinal Data, Margot Selosse, Julien Jacques, Christophe Biernacki
The R Journal
Ordinal data are used in many domains, especially when measurements are collected from people through observations, tests, or questionnaires. ordinalClust is an innovative R package dedicated to ordinal data that provides tools for modeling, clustering, co-clustering and classifying such data. Ordinal data are modeled using the BOS distribution, which is a model with two meaningful parameters referred to as "position" and "precision". The former indicates the mode of the distribution and the latter describes how scattered the data are around the mode: the user is able to easily interpret the distribution of their data when given these two parameters. The …
Tulip: A Toolbox For Linear Discriminant Analysis With Penalties, Yuqing Pan, Qing Mai, Xin Zhang
Tulip: A Toolbox For Linear Discriminant Analysis With Penalties, Yuqing Pan, Qing Mai, Xin Zhang
The R Journal
Linear discriminant analysis (LDA) is a powerful tool in building classifiers with easy computation and interpretation. Recent advancements in science technology have led to the popularity of datasets with high dimensions, high orders and complicated structure. Such datasetes motivate the generalization of LDA in various research directions. The R package TULIP integrates several popular high-dimensional LDA-based methods and provides a comprehensive and user-friendly toolbox for linear, semi-parametric and tensor-variate classification. Functions are included for model fitting, cross validation and prediction. In addition, motivated by datasets with diverse sources of predictors, we further include functions for covariate adjustment. Our package is …
Testing The Equality Of Normal Distributed And Independent Groups’ Means Under Unequal Variances By Doex Package, Mustafa Cavus, Berna Yazıcı
Testing The Equality Of Normal Distributed And Independent Groups’ Means Under Unequal Variances By Doex Package, Mustafa Cavus, Berna Yazıcı
The R Journal
In this paper, we present the doex package contains the tests for equality of normal distributed and independent group means under unequal variances such as Cochran F, Welch-Aspin, Welch, Box, Scott-Smith, Brown-Forsythe, Johansen F, Approximate F, Alexander-Govern, Generalized F, Modified Brown-Forsythe, Permutation F, Adjusted Welch, B2, Parametric Bootstrap, Fiducial Approach, and Alvandi Generalized F-test. Most of these tests are not available in any package. Thus, doex is easy to use for researchers in multidisciplinary studies. In this study, an extensive Monte-Carlo simulation study is conducted to investigate the performance of the the tests for equality of normal distributed group means …
Frames Of Error: Three Behavioral Approaches To Reducing Stigma Towards People With Disabilities, Rocco Giovanni Catrone
Frames Of Error: Three Behavioral Approaches To Reducing Stigma Towards People With Disabilities, Rocco Giovanni Catrone
Dissertations
What makes a person disabled is a much-debated topic with some focusing on the individuals impairments (putting the onus of disability on the individual) while others focus on how the environment (both architectural and social) exacerbates an individual’s impairments and creates the conceptualization of disability (putting the onus of disability on society). No matter how a person with a disability (PWD) is categorized, they are met with healthcare, education, and work disparities that are perpetuated both unintentionally and intentionally. This paper examines the various ways disability and subsequently stigma arises from a variety of viewpoints both within and outside the …
Has The Pandemic Brought About A Healthier Lifestyle Among Adults?, Amirul Roslee
Has The Pandemic Brought About A Healthier Lifestyle Among Adults?, Amirul Roslee
Introduction to Research Methods RSCH 202
This study is the first in Singapore to examine how the lockdown had an impact on lifestyle habits among adults above 18 years old in Singapore. The results were collected through an online survey consisting of 18 questions. Linear Regression is used to find the relation between healthier people and the variables. The data analysis determined whether significant differences exist between essential workers and non-essential workers. The proposed research will aim to gain a deeper understanding of the lifestyle changes affected by the lockdown mainly with regards to exercise, sleeping habits, and mode of working.
The Five Stages Of Team Development, Caitlin Collins, Ethan Castro
The Five Stages Of Team Development, Caitlin Collins, Ethan Castro
Goal 3: Interpersonal Intelligence Narrative
Purpose: Provide students an introduction to existing business/psychology teachings on group dynamics and the five distinct stages of team development likely to be experienced in any group setting.
How Peer Support Specialists Uniquely Initiate And Build Connection With Young People Experiencing Homelessness, James Erangey, Connor Marvin, Danielle Maude Littman, Meredith Mollica, Kimberly Bender, Tom Lucas, Tara Milligan
How Peer Support Specialists Uniquely Initiate And Build Connection With Young People Experiencing Homelessness, James Erangey, Connor Marvin, Danielle Maude Littman, Meredith Mollica, Kimberly Bender, Tom Lucas, Tara Milligan
Graduate School of Social Work: Faculty Scholarship
Young people experiencing homelessness are often apprehensive to engage in conventional service systems due to prior mistreatment by providers and others in their lives, as well as stigma associated with accessing services. Even when relationships between service providers and young people are initiated, they often end prematurely. Mutual aid, or peer-to-peer support, has a long and promising history within the mental health field, yet has received little empirical attention in work with young people experiencing homelessness. The present study used participatory qualitative methods to understand how peers uniquely initiate and build connection with young people experiencing homelessness. Through interviews and …
Determining The Molecular Events Underlying The Role Of Estradiol In Mediating Sex Differences In Cocaine Reward., Saurabh Sanjeev Kokane
Determining The Molecular Events Underlying The Role Of Estradiol In Mediating Sex Differences In Cocaine Reward., Saurabh Sanjeev Kokane
Psychology Dissertations - Archive
Research has demonstrated that women rapidly progress from recreational cocaine use to dependence, consume greater quantities of cocaine, experience more positive subjective effects of cocaine and have higher incidences of relapse during abstinence. These effects have been well replicated in animal models of cocaine addiction and indicate an enhanced sensitivity and therefore, vulnerability of females to cocaine addiction. This increased vulnerability of women and female animals to cocaine addiction has been attributed to enhanced cocaine reward. Furthermore, it has been demonstrated that the female hormone estradiol (E2) is a key mediator of the aforementioned effects of cocaine in women and …
Humility And Leadership Potential: Testing A Moderated Moderated Mediation Model, Christa Mason
Humility And Leadership Potential: Testing A Moderated Moderated Mediation Model, Christa Mason
Psychology Dissertations - Archive
Despite the growing research on humble leadership, views on humility remain mixed and little is known about how humble individuals become leaders. To address this gap, this study examined how expressed humility was related to perceptions of an aspiring leader’s warmth, competence, and leadership potential. It tested a moderated moderated mediation model to assess: (1) if perceived warmth and competence explained the relationship between humility and leadership potential, and (2) if this relationship varied based on an aspiring leader’s perceived dominance and gender. Professionals with hiring experience (N = 187) evaluated male and female leadership candidates who demonstrated different combinations …
The Pain In The Pleasure: Electrophysiological Analysis Of The Tail Region Of The Ventral Tegmental Area (Tvta), Akshay Parchure
The Pain In The Pleasure: Electrophysiological Analysis Of The Tail Region Of The Ventral Tegmental Area (Tvta), Akshay Parchure
Psychology Dissertations - Archive
The mesolimbic (midbrain) reward system is well documented to be involved with the analgesic effects of opioids, which involves the ventral tegmental area (VTA) causing release of dopamine (DA). The dopamine neurons from the ventral tegmental area (VTA) directly innervate the nucleus accumbens (NAc) and the prefrontal cortex via D1 DA Receptors. GABAergic inhibition of VTA DA system occurs regularly, but in 1990s Johnson and North showed the administration of opioids led to hyperpolarization of GABA interneurons in the VTA removing this inhibition, further leading to the “disinhibition model”. However, more recent studies have defined a new structure heavily influencing …