Digital Commons Network^™

Food Accessibility Related To The Double Your Dollar Program, Julia Carlson, Heather Friedrich, Mechelle Bailey, Curt Rom

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

The Double Your Dollar (DYD) Program is a program that gives Supplemental Nutrition Assistance Program (SNAP) beneficiaries and Senior Farmers Market Nutrition Program (SFMNP) participants match dollars to spend at local farmers markets. The DYD’s goal is to incentivize healthy eating among individuals of low income and promote spending at farmers markets. Food insecurity affects over 60,000 individuals in Washington and Benton counties in Arkansas. The aim of this study was to assess how the DYD program impacted users’ food accessibility and how the program could be improved for the future. A survey was used to address basic demographics, type, …

Contribution Of Adaptive Immune Responses In Chronic Lung Diseases, Thi Kim Tran-Nguyen

All ETDs from UAB

Immune dysregulation is a hallmark of various chronic lung diseases such as Chronic Obstructive Pulmonary Diseases (COPD) and Idiopathic Pulmonary Fibrosis (IPF). Previous studies in our lab have shown evidences of autoimmunity such as increases in autoantibodies, abnormal T cell profile, immune complex deposition and the presence of ectopic lymphoid structures in the lung of these patients. This thesis consolidates two separate projects about various aberrant immune responses in these diseases. The first project identified Glucose-Regulated-Protein 78 (GRP78) as the common autoantigen in COPD and characterized how GRP78 autoantibodies may increase COPD mortality via its atherogenic effects. I demonstrated that …

Understanding Financial Hardship In Women With Breast Cancer, Courtney Williams

All ETDs from UAB

Individuals with cancer are at risk of material, psychological, and behavioral financial hardship due to costly new treatments, increasing time on treatment, and longer survival. Breast cancer is an ideal environment to study financial hardship. Treatment options for metastatic breast cancer are heterogeneous due to differences in patient characteristics, disease biology, and because it has the largest number of treatment options of any metastatic cancer. In early stage breast cancer, treatment options include multimodality treatments, including surgery, radiation, and medical therapy (chemotherapy, hormone therapy, targeted therapy), with the choice for each modality being dependent on the other modality decisions. Despite …

Assessment Of Emergency Department High Utilizer Program In Public Health System Setting, Michael Malaise

All ETDs from UAB

is study examined whether a case management model designed to reduce emergency department utilization among patients described as super-utilizers in a public health system could also reduce the per patient cost of those super-utilizers. The setting for this study was a large public health system in a major metropolitan area. The study focused on a low-income, urban population. Given the program’s stated desire to improve the self-efficacy of patients over time so that they could take more ownership of their own health status, this study reviewed the program within the framework of self-efficacy theory. This research predicted that the case …

Molecular Regulation Of Glioblastoma Spatial Heterogeneity And Therapeutic Resistance, Soniya Bastola

All ETDs from UAB

Glioblastoma multiforme (GBM) is a highly invasive, highly vascularized, and heterogeneous malignant tumor of the brain. Due to the highly infiltrative phenotype of GBM, surgery often leaves behind residual tumor cells. In many cases, recurrence occurs close to the surgical margin suggesting the role of these remaining cells in promoting tumor aggressiveness. Rapidly growing tumor creates subsequent hypoxic, and hypovascular core due to limited nutrients, whereas tumor cells in the leading edge have access to nutrients from vasculature enriched microenvironment. Studies have identified the cellular and molecular heterogeneity between the tumors in core and edge. Still, their mechanisms of intercellular …

Race, Type Ii Diabetes Mellitus And Vertebral Fragility Fractures: A Cross-Sectional Analysis From Nhanes, Yuchen At Xiao

All ETDs from UAB

IntroductionThis study examined the association between race and bone health, and if T2DM modifies this association in a diverse sample of adults. Methods We conducted a cross-sectional study using the 2013-2014 National Health and Nutrition Examine Survey (NHANES) data. Bone health outcomes included lumbar spine BMD (lowered BMD based on T-scores <-1), and vertebral deformities, assessed via vertebral fracture assessment (VFA), including presence, number of deformities, and severity ratio of deformities. T2DM status and other demographic, lifestyle, and health characteristics were self-reported via questionnaire data. To assess if T2DM modifies the association between race and bone health outcomes, we conducted stratified analyses using logistic regression for dichotomous outcomes, Poison regression for count outcomes, and linear regression for continuous outcomes. Results Non-Hispanic (NH) Blacks have significantly less odds of being lowered BMD and osteoporosis comparing to NH-Whites in the crude model and significantly less odds of having vertebral deformities comparing to NH-White in both crude and adjusted model for non-diabetic participants. Such differences are not observed in diabetic groups. Participants in Other race group have significantly more odds of being lowered BMD comparing to NH-Whites in the adjusted model for both diabetic and non-diabetic groups. And have significantly more odds of having vertebral deformities in the diabetic group, crude and adjusted, yet the differences are not significant in non-diabetic groups. Similar results were seen in the number of deformities and total bone loss ratio. The potential modification effect of T2DM was not significant in these models. Conclusions In our national evaluation, bone health differs not only by race and ethnic group but also by T2DM status. The protective vertebral fragility effects observed among NH-Blacks was no longer present among those with diabetes. Likewise, among participants in other racial and ethnic groups, T2DM seemed to magnify the association of worse vertebral fragility. Such trends indicate a potential modifying effect of participants’ T2DM status and should be noted clinically, yet more studies are required for more precise results.

A Modified Standard American Diet (Msad) Induces Physiological Parameters Associated The With Metabolic Syndrome In C57bl/6j Mice, Sophie Bru Chehade

All ETDs from UAB

Obesity manifests physiologically in multiple organ systems of the body, typically increasing the risk of developing cardiometabolic disorders. Researchers have questioned the causative role that western dietary patterns have on disease pathogenesis and have speculated that quality and quantity of dietary fats and/or carbohydrates have a predictive role in the development of these disorders. Standard reference diets such as the AIN-93 rodent diet have historically been used to promote optimal animal model health and reduce variation of results across experiments. These diets have been invaluable to murine research; however, their translational value in studying human nutrition-related pathologies is limited. Early …

Impact Of Diet And Meal Timing On Time-Of-Day Dependent Hippocampal Function, Jennifer Davis

All ETDs from UAB

Circadian rhythms are biological processes that cycle every ~24 hours and have allowed life to adapt for optimal function across the day. These rhythms are present in all tissues in the body and are coordinated to the light/dark cycle by the suprachiasmatic nucleus (SCN) in the hypothalamus. Along with active-rest cycles, cognitive performance fluctuates across the course of the day, peaking during the active phase. In addition to the light cycle, food and meal timing can provide signaling cues to extra-SCN tissues. Food access only during the inactive phase results in weight gain and memory impairment. High fat diet protocols …

Calibration Of Periodontal Diagnosis Among Participants Of Various Dental Education Levels, Shadi Alkhoury

All ETDs from UAB

ABSTRACT: The purpose of this project is to assess the level of calibration among dental students of two different education levels and postgraduate students of two different dental specialties during diagnosis and treatment planning of clinical cases with various levels of periodontal involvement, using the 2018 Classification of Periodontal and Peri-implant Diseases and Conditions. Fifty-seven second year dental students (D2), 45 fourth year dental students (D4), 17 orthodontic postgraduate students (OS) and 12 postgraduate periodontology (PS) students were presented with an anonymous survey of 10 different cases, each with 5 choices of diagnosis and 7 therapeutic approaches. Consensus diagnosis was …

Early Childhood Quality Of Education And Late-Life Cognitive Function In A Population-Based Sample From Puerto Rico, Cheyanne Celine Barba

All ETDs from UAB

In general, greater years of education is associated with reduced risk of cognitive impairment in older adulthood, but the strength of this association has been found to differ by study population. Additionally, quality of education is understudied, despite evidence that quality of education and, in turn, literacy, may be additional indicators of cognitive reserve. This thesis examined years of education, literacy, and childhood quality of education indicators in relation to late-life cognitive outcomes in an older Puerto Rican population. We hypothesized that greater years of education, literacy, and quality of childhood education would be positively associated with each other, as …

Self-Awareness Of Functional Deficits In Older Adults With Mild Cognitive Impairment, Kayla Ann Steward

All ETDs from UAB

Performance of instrumental activities of daily living (IADLs) can become compromised in older adults with mild cognitive impairment (MCI). Poor self-awareness of deficits, also known as anosognosia, occurs in a substantial minority of those with MCI and varies in extent depending on the domain examined. This dissertation attempts to explain the inter- and intra-patient variability in anosognosia by examining (1) differences in objective IADL performance and self-awareness of functional difficulties between those with amnestic single- (-ASD) and multi-domain (-AMD) MCI, and by examining (2) the neuropsychological and (3) neuroanatomical correlates of anosognosia for IADLs in older adults across a broad …

O'Kei: An American Novel, Boris Pilnyak, Ronald D. Leblanc (Translator)

Faculty Publications

On January 4, 1931, Boris Pilnyak (1894-1938) wrote a letter to Joseph Stalin, pleading with the Soviet leader to grant him permission to travel to the United States in order to conduct research for an ambitious book project he was undertaking that would compare communist Russia favorably to capitalist America. Pilnyak’s request received official approval, and a few months later the writer set off for the U.S., arriving in New York by steamer on March 12, 1931, and remaining in the country until August 3, 1931. During his nearly five-month stay in America, Pilnyak became acquainted with a number of …

Psychometric Evaluation Of A Perceived Barriers To Medication Adherence Instrument And Association Between Perceived Barriers And Patient Characteristics, Lynn Andreae

All ETDs from UAB

Medication adherence is an important component of diabetes management, yet nonadherence is common and has substantial patient and economic costs. In order to achieve meaningful improvements in medication adherence, clinicians and researchers need good ways of both identifying those at risk of nonadherence and ascertaining the specific reasons driving nonadherence in those patients. Current options for self-reported medication adherence are limited in their vulnerability to response bias, which may lead to overestimation of adherence. A measure that assesses perceived barriers to medication adherence may be a useful alternative, as it may identify patients at risk of nonadherence while reducing socially …

Spectrum 2020, Saint Mary's College Of California

The Undergraduate Spectrum

No abstract provided.

Individual And Community Social Determinants Of Health Associated With Diabetes Management In A Mexican American Population, Kehe Zhang, Belinda Reininger, Miryoung Lee, Qian Xiao, Cici Bauer

Faculty, Staff and Student Publications

Background: Diabetes is a major health burden in Mexican American populations, especially among those in the Lower Rio Grande Valley (LRGV) in the border region of Texas. Understanding the roles that social determinants of health (SDOH) play in diabetes management programs, both at the individual and community level, may inform future intervention strategies.

Methods: This study performed a secondary data analysis on 1,568 individuals who participated in Salud y Vida (SyV), a local diabetes and chronic disease management program, between October 2013 and September 2018 recruited from a local clinic. The primary outcome was the reduction of hemoglobin A1C (HbA1C) …

Reprograming Neuronal Cells By Overexpression Of Fibroblast-Specific Transcription Factors, Abdulmohsen Alanazi

Masters Theses

In mammals, a complex system of regulatory signals distinguishes tissues, structures and functions. Combinations of transcription factors and co-factors regulate activation and repression of genes that result in cellular differentiation. Whole genome arrays allow the monitoring of genomic expression in specific tissues. Fibroblast microarray studies have shown candidate genes that may be involved in fibroblast identification, including genes that express transcription factors Prrx1, Snai2 and Twist1. A previous study showed that the Prrx1 and Snai2 could reactivate a fibroblast phenotype in hybrid cells that had lost fibroblast identity. Furthermore, overexpression of these factors in liver-derived cells strongly repressed liver gene …

Leadership Development In East Africa: A Case Study Of A Multi-Year College Student Leadership Program, Gregory Armen Muger

Theses and Dissertations

Effectual and ethical leadership is a top need throughout all sectors in Sub-Saharan Africa (Adadevoh, 2007; Ncube, 2010). Unfortunately, there is currently very scant literature on Sub-Saharan African leadership theory or programming (Bolden & Kirk, 2009). A large Christian nonprofit organization operated a multi-year servant leadership-based Christian leadership program for thousands of college students throughout sites in East Africa called the Leadership Development Program (LDP). The LDP endeavored to groom local, ethical, and capable leaders. Therefore, studying the LDP model and its impacts could add significant value to Sub-Saharan African leadership practitioners as well as add to the limited body …

Childhood And Adolescent Obesity Prevention In Twin Falls, Idaho, Allison Welch

Selected Social Change Portfolios in Prevention, Intervention, and Consultation

Obesity, a condition that negatively affects an individual’s physical and mental health, is a growing problem in Twin Falls, Idaho. Like the United States as a whole, Twin Falls County is experiencing an obesity crisis. According to the Centers for Disease Control and Prevention ([CDC], n.d), the national obesity rate has increased by 12% from 2000 to 2018. The Twin Falls County obesity rate has increased from 21% in 2011 to 33% in 2020 (County Health Rankings & Roadmaps, 2018). While it took the nation 18 years to increase the obesity rate by 12% (CDC, n.d.), it only took Twin …

Promoting Healthy Strategies To Reduce Obesity, Jarae Swanstrom

Selected Social Change Portfolios in Prevention, Intervention, and Consultation

Sandpoint is a rural community in Northern Idaho with a population of 9,000 in the city limits and 46,000 within the county. Sandpoint is the largest town and the primary source for all services within Bonner County. There is an abundance of outdoor activities to enjoy with the largest and deepest lake in Idaho and many mountains nearby. Even though Sandpoint residents have many options to stay physically active and maintain a healthy weight, a continual rise in obesity within the community and across America has become a trend (County Health Rankings & Roadmaps, 2018). Likewise, the lack of affordable …

Substance Use In Pender County, North Carolina., Khristine Winstead

Selected Social Change Portfolios in Prevention, Intervention, and Consultation

This portfolio explores substance use in Pender County, NC. Recent data from the community health opinion survey indicates that substance use in Pender County is the number one community issue (Pender County Health Department, 2018). From 2012 through 2016, the number of Pender County resident babies hospitalized with drug withdrawal syndrome per 1,000 was 20. To contrast, as a whole, the state of North Carolina recorded 9 per 1,000 (Pender County Health Department, 2018). To date, the local management entity (LME) in Pender County responsible for managing state and federally funded services, including substance use disorders, is Trillium Health Resources. …

Obesity Prevention In Morrow County, Oregon, Chris Humphreys

Selected Social Change Portfolios in Prevention, Intervention, and Consultation

Morrow County, Oregon, is a county located in the north central part of Oregon, right along the Columbia River. The county’s industrial profile is a mix between large agricultural producers, longtime family ranches, and major tech companies like Amazon and Facebook. The largest town, Boardman, only has a population of around 3400 persons (2018), with several other smaller towns making up the rest of the county. Many of the subjects who work in Morrow County commute from several larger towns in adjacent counties. One result of this is that there are no open-to-the-public fitness clubs in Morrow County. Any access …

Miyokos V Ross, Northern District Of California

Historical and Topical Legal Documents

No abstract provided.

Incorporating Physiology Into Species Distribution Models Moderates The Projected Impact Of Warming On Mediterranean Marine Species, Inbal Gamliel, Yehezkel Buba, Tamar Guy-Haim, Tal Garval, Demian A. Willette, Gil Rilov, Jonathan Belmaker

Biology Faculty Works

Species distribution models (SDMs) correlate species occurrences with environmental predictors, and can be used to forecast distributions under future climates. SDMs have been criticized for not explicitly including the physiological processes underlying the species response to the environment. Recently, new methods have been suggested to combine SDMs with physiological estimates of performance (physiology-SDMs). In this study, we compare SDM and physiology-SDM predictions for select marine species in the Mediterranean Sea, a region subjected to exceptionally rapid climate change. We focused on six species and created physiology-SDMs that incorporate physiological thermal performance curves from experimental data with species occurrence records. We …

On Extreme Perception Bias, Emerico Habacon Aguilar, Klarizze Martin Puzon, Imelda Revilla Molina

DLSU Business & Economics Review

This note investigates perception bias: To what extent do individual opinions confound reality? We estimated the relative gap between self-declared estimates and real data. With a sample of respondents from Laguna, Philippines, we asked about the prevalence of diabetes and smartphone usage. We observed a trend of judgment miscalibration. Responses exhibit significant deviation from facts; for example, inaccuracies can go as high as seven times the real value. Especially for estimates on smartphone ownership, bootstrapped quantile regression models showed that perception bias is associated with age.

Social Grants Transfer Program: The Role Of Policy Actors In Policy Implementation, David Quist

Walden Dissertations and Doctoral Studies

The scholarly literature lacks the knowledge to support the view that policy actor activities in policy streams were not limited to the 3 initial stages of the policy cycle. Finding evidence through a study to either back or refute this view among scholars was important to explain how policy implementation effort works to yield results. Thus, the purpose of this general qualitative and policy implementation research was to generate additional knowledge about the role of policy actors in policy implementation. The 5-stream framework theoretical lens for this study suggested that the policymaking process involved 5 streams with active policy actors …

Effects Of Environmental Heterogeneity And Temporal Variation On Ecological Relationships Of Vegetation In A Seasonally Dry Tropical Forest In Brazil, Alisson Borges Miranda Santos, Nathalle Cristine Alencar Fagundes, Cleber Rodrigo Souza, Vinicius Andrade Maia, Wilder Bento Da Silva, Gabriela Gomes Pires De Paula, Felipe De Carvalho Araujo, Polyanne Coelho, Natália Aguiar-Campos, Diego Teixeira Girardelli, Jean Daniel Morel, Rubens Manoel Dos Santos

Turkish Journal of Botany

Species distribution patterns, community structure, and dynamics are determined on a small scale by soil and habitat heterogeneity. The aim of this work is to evaluate the temporal changes in composition and structure of a tree community, revealing the ecological drivers of the observed vegetation patterns. For 16 years (2000, 2005, 2010, and 2016) we monitored the temporal variations in structure and floristic composition of a semideciduous seasonal forest through 20 × 20 m2 (400 m2) plots, totaling 2.08 ha of sampled area encompassing Cambisol (0.4 ha), Oxysol (1.12 ha), and Nitosol (0.56 ha) soil classes. These tree communities were …

Enhanced Stress Tolerance In Transformed Ajuga Bracteosa Wall. Ex Benth. Regenerants By Upregulated Gene Expression Of Metabolic Pathways, Samina Rubnawaz, Waqas Kayani, Rashid Mahmood, Bushra Mirza

Turkish Journal of Botany

The rol oncogenes of Agrobacterium rhizogenes enhance the production of medicinally important compounds in plants and provide a first barrier against the overproduction of reactive oxygen species during biotic and abiotic stress. This study was designed to evaluate the expression of genes involved in biosynthetic pathways and their impact on metabolic contents and environmental stress tolerance in regenerated Ajuga bracteosa Wall. ex Benth. After successful transformation, real-time quantitative PCR confirmed the increased expression (1.94-6.59-fold) of HMGR, HDS, FDS, PAL, and TTG1 genes in transgenic lines. Furthermore, GC-MS coupled with principal component analysis revealed diverse concentrations of 97 metabolites in A. …

Uncooperative Environmental Federalism 2.0, Jonathan H. Adler

Faculty Publications

As a presidential candidate, Donald Trump promised to curtail federal environmental regulation and empower the states. Has the Trump Administration made good on these pledges to reinvigorate cooperative federalism and constrain environmental regulatory overreach by the federal government? Perhaps less than one would think. This Essay provides a critical assessment of the Trump Administration’s approach to environmental federalism. Despite the Administration’s embrace of “cooperative federalism” rhetoric, environmental policy reforms have not consistently embodied a principled approach to environmental federalism in which the state and federal governments are each encouraged to focus resources on areas of comparative advantage.

Comparative Study On Chinese Network Imported Food Safety Supervision System, Jingquan Wang

Theses

This paper aims to improve the efficiency of food safety supervision and the effective way to ensure food safety through the comparative study of the imported food safety supervision system of China's network, and the comparative study of the main methods to ensure food safety. In this paper, according to the basic theory of food safety, for the world's major developed countries government food safety regulatory system, the Chinese government's food safety regulatory system research, China's food regulatory measures related to a new model idea, several parts, and discover network imported food safety supervision system in our country's own insufficiency, …

Vitamin D Fortification Of Processed Meat To Reduce Self-Reported Deficiencies: Consumer Acceptance In The Irish Market, Emma Lynn Donaldson

Theses

It is believed that many areas of the world are experiencing a Vitamin D deficiency pandemic. With Ireland’s geographic location, genetic characteristics, and the reemergence of rickets in Ireland in the early noughties; Ireland is a part of the deficiency pandemic. Vitamin deficiencies have historically been handled effectively through food fortification schemes, however additional food products, like processed meats, need to be assessed for their ability to address the deficiency and consumer acceptance. Aim: The aim of this study is to analyse the general consumer acceptance of future Vitamin D fortified, processed meats in the Irish market, in order to …