Digital Commons Network^™

Evaluation Of The Psychometric Properties Of A Version Of The London Measure Of Unplanned Pregnancy For Women’S Partners, Geraldine Barrett, Jennifer A. Hall, Beth Howden, Dilisha Patel, Jill Shawe, Judith Stephenson

School of Nursing and Midwifery

BackgroundThe role of women’s partners in pregnancy planning has gained importance with the development of preconception care. The measurement of pregnancy planning/intention has also changed in the last two decades with the development of psychometric measures such as the London Measure of Unplanned Pregnancy (LMUP). This analysis aimed to evaluate the psychometric properties of a version of the LMUP for women’s partners in the UK. MethodsThe LMUP items, adapted for completion by partners, were piloted and included in a survey of (mainly male) partners in three antenatal clinics in London, UK, as part of a study of pre-pregnancy health and …

Baroreflex Sensitivity During Positional Changes In Patients With Traumatic Brain Injury, Norma D. Mcnair

Dissertations

Traumatic brain injury (TBI) affects 1.7 million Americans annually leading to significant morbidity and health care costs. An important cause of morbidity in TBI is secondary brain injury due to abnormal cerebrovascular autoregulation (CA). Standard measures of CA are not amenable to use outside of the intensive care unit (ICU) and patients continue to be at risk for secondary brain injury post- ICU. Baroreflex sensitivity (BRS) is a non-invasive assessment of autonomic tone that may be useful in evaluating CA. Evaluation of BRS and its relation to CA has not been examined in patients with TBI and predictors of CA …

Immunotherapy In Hepatocellular Cancer Patients With Mild To Severe Liver Dysfunction: Adjunctive Role Of The Albi Grade, David J Pinato, Takahiro Kaneko, Anwaar Saeed, Tiziana Pressiani, Ahmed Kaseb, Yinghong Wang, David Szafron, Tomi Jun, Sirish Dharmapuri, Abdul Rafeh Naqash, Mahvish Muzaffar, Musharraf Navaid, Chieh-Ju Lee, Anushi Bulumulle, Bo Yu, Sonal Paul, Neil Nimkar, Dominik Bettinger, Hannah Hildebrand, Yehia I Abugabal, Celina Ang, Thomas U Marron, Uqba Khan, Nicola Personeni, Lorenza Rimassa, Yi-Hsiang Huang

Faculty, Staff and Students Publications

Immune checkpoint inhibitors (ICI) have shown positive results in patients with hepatocellular carcinoma (HCC). As liver function contributes to prognosis, its precise assessment is necessary for the safe prescribing and clinical development of ICI in HCC. We tested the accuracy of the albumin-bilirubin (ALBI) grade as an alternative prognostic biomarker to the Child-Turcotte-Pugh (CTP). In a prospectively maintained multi-centre dataset of HCC patients, we assessed safety and efficacy of ICI across varying levels of liver dysfunction described by CTP (A to C) and ALBI grade and evaluated uni- and multi-variable predictors of overall (OS) and post-immunotherapy survival (PIOS). We studied …

Effects Of Different Factors On The Hypocotyls Protoplast Isolation Of Common Sainfoin, Yupeng Luo, Bo Zhang, Aiping Chen

IGC Proceedings (1977-2023)

No abstract provided.

Cholera In Present-Day Haiti: Interpretations Of And Responses To A Contemporary Enemy, Melissa Frick

Swarthmore Undergraduate History Journal

Note: In lieu of an abstract, this is the article's first paragraph.

"In his introduction to Epidemics and Ideas, Paul Slack calls to revive the study of social history of epidemics, wanting to show how societies cope with, react to, and interpret crises of disease. He reviews historian Richard Evans’ notion of the “common dramaturgy” to all epidemics, which states that human society responds to mass infection through an inherent response mechanism. Disease presents common dilemmas - including decisions on how the disease is transmitted, whom it infects, who is to blame, and incites common responses. Furthermore, Slack suggests that …

Theatrical Illness: Tuberculosis And Hiv As Presented By "La Boheme" And "Rent", Jessica Downing

Swarthmore Undergraduate History Journal

Note: In lieu of an abstract, this is the article's first paragraph.

"The musical Rent made its Broadway debut on January 25, 1996, a century after the opening performance of the opera, La Boheme. This correlation was a coincidence, though Rent draws significantly on the story of La Boheme, to the extent that a New York Times reviewer deemed it a "contemporary answer to Puccini's 'Boheme."' Each of these productions presents the troubles and tragedies of the bohemian lifestyle in a specific time and place-La Boheme in Paris during the 1830s and Rent in New York City during 1989. Disease, …

"Loathsome And Dangerous": Health Screening In A Globalized World, Gabriel Hearn-Desautels

Swarthmore Undergraduate History Journal

Note: In lieu of an abstract, this is the article's first paragraph.

"As the world has become steadily more interdependent over the last century, disease has been able to spread with increasing ease. As a consequence of this new danger, the international community has changed the way that it understands contagion, and public health has taken on new roles and new meanings around the world. I argue that the globalization of public health and the relatively new perception of diseases as “global” threats have dramatically altered practices of health screening, both at the border and beyond. Above all, these changes …

Full Issue: Special Issue On Infectious Disease, Editorial Board

Swarthmore Undergraduate History Journal

No abstract provided.

Primary Jurisdiction And The Limits Of Measurement In Mass Litigation, Jeff Lingwall

Pace Law Review

This Article examines the use of primary jurisdiction through the lens of institutional economics and the ongoing revolution in pre-suit, plaintiff-side testing in mass litigation. In this setting, primary jurisdiction serves a necessary pro-agency institutional role. The ability of plaintiffs’ attorneys to easily generate sophisticated laboratory testing results has allowed them to create a quasi-regulatory quality-control regime for defendants’ products and extract value from it through enhanced settlements. This offers defendants the burdens of regulation without the benefits of uniformity or policymakers with subject-matter expertise and capacity for public input. Primary jurisdiction enables defendants in mass litigation to move these …

Discovery Of A Role For Rab3b In Habituation And Cocaine Induced Locomotor Activation In Mice Using Heterogeneous Functional Genomic Analysis, Jason A. Bubier, Vivek M. Philip, Price E. Dickson, Guy Mittleman, Elissa J Chesler

Faculty Research 2020

Substance use disorders are prevalent and present a tremendous societal cost but the mechanisms underlying addiction behavior are poorly understood and few biological treatments exist. One strategy to identify novel molecular mechanisms of addiction is through functional genomic experimentation. However, results from individual experiments are often noisy. To address this problem, the convergent analysis of multiple genomic experiments can discern signal from these studies. In the present study, we examine genetic loci that modulate the locomotor response to cocaine identified in the recombinant inbred (BXD RI) genetic reference population. We then applied the GeneWeaver software system for heterogeneous functional genomic …

Labib Riachi V. Prometheus Group

2020 Decisions

USDC for the District of New Jersey

Take 10 Program Effects On Fifth Grade Academic Achievement, Emily Janes

Dissertations

Problem Less than one-fourth of children reach their recommended 60-minutes of daily physical activity. Inactivity can result in poor academic performance; whereas physical activity stimulates brain functions responsible for regulating comprehension and attention, release of brain chemicals to improve learning, and enhances neurogenesis resulting in better cognition. The purpose of this quality improvement project was to evaluate the Take 10 exercise program in a rural, Midwestern elementary school fifth grade classroom.

Methods An observational, descriptive design with a purposeful sample of fifth-grade students in a rural elementary school. Grades in math, science, and reading were examined the semester before (quarter …

Physiochemical Characteristics Of Hot And Cold Brew Coffee Chemistry: The Effects Of Roast Level And Brewing Temperature On Compound Extraction., Niny Z. Rao, Megan Fuller, Meghan D Grim

College of Life Sciences Faculty Papers

The role of roasting in cold brew coffee chemistry is poorly understood. The brewing temperature influences extraction processes and may have varying effects across the roast spectrum. To understand the relationship between brew temperature and roast temperature, hot and cold brew coffees were prepared from Arabica Columbian coffee beans roasted to light, medium, and dark levels. Chemical and physical parameters were measured to investigate the relationships among degree of roast, water temperature, and key characteristics of resulting coffees. Cold brew coffees showed differential extraction marked by decreased acidity, lower concentration of browned compounds, and fewer TDS indicating that cold water …

Towards Refining Alzheimer's Disease Into Overlapping Subgroups, Erin R. Hascup, Kevin N Hascup

Articles

Alzheimer’s disease (AD) is an age-related neurodegenerative disorder characterized by progressive anterograde amnesia, cerebral atrophy, and eventual death. Current treatment has limited efficacy and cannot decelerate the disease progression. Clinical trials targeting the removal of the neuropathological hallmarks of AD, including accu- mulation of amyloid plaques or neurofibrillary tangles, have failed to modify disease progression. Without new or innovative hypotheses, AD is poised to become a public health crisis within this decade. We present an alternative hypothesis—that AD is the result of multiple interrelated causalities. The intention of this manuscript is to initiate a discussion regarding these multiple causalities and …

Epidemiology Of Cancers In Men Who Have Sex With Men (Msm): A Protocol For Umbrella Review Of Systematic Reviews, Manoj Kumar Honaryar, Yelena Tarasenko, Maribel Almonte, Vitaly Smelov

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

While earlier studies on men having sex with men (MSM) tended to examine infection-related cancers, an increasing number of studies have been focusing on effects of sexual orientation on other cancers and social and cultural causes for cancer disparities. As a type of tertiary research, this umbrella review (UR) aims to synthesize findings from existing review studies on the effects of sexual orientation on cancer. Relevant peer-reviewed systematic reviews (SRs) will be identified without date or language restrictions using MEDLINE, Cochrane Database of Systematic Reviews, and the International Prospective Register for Systematic Reviews, among others. The research team members will …

Determination Of Reference Intervals For Common Chemistry And Immunoassay Tests For Kenyan Adults Based On An Internationally Harmonized Protocol And Up-To-Date Statistical Methods, Geoffrey Omuse, Kiyoshi Ichihara, Daniel Maina, Mariza Hoffman, Elizabeth Kagotho, Alice Kanyua, Jane Mwangi, Caroline Wambua, Angela Amayo, Peter Ojwang, Zul Premji, Rajiv Erasmus

Pathology, East Africa

Background: Due to a lack of reliable reference intervals (RIs) for Kenya, we set out to determine RIs for 40 common chemistry and immunoassay tests as part of the IFCC global RI project.

Methods: Apparently healthy adults aged 18–65 years were recruited according to a harmonized protocol and samples analyzed using Beckman-Coulter analyzers. Value assigned serum panels were measured to standardize chemistry results. The need for partitioning reference values by sex and age was based on between-subgroup differences expressed as standard deviation ratio (SDR) or bias in lower or upper limits (LLs and ULs) of the RI. RIs …

Anatomical Organization And Distinction Of The Sympathetic Inputs To Interscapular Brown Adipose Tissue And Inguinal White Adipose Tissue In The Mouse, Clara Jane Huesing

LSU Doctoral Dissertations

Adipose tissue is a dynamic endocrine organ that contains both the problem and the solution to discovering new therapies for individuals with obesity. Excessive adipose tissue disrupts energy balance and causes a host of comorbidities like insulin resistance and hypertension. On the other hand, adipose tissue is essential for life. During periods of energy demand, sympathetic nerve activity in brown and white adipose tissue stimulates thermogenesis and lipolysis; both of which decrease body weight and improve metabolic health. Therefore, comprehensive insight into the organization of sympathetic innervation and how it communicates with adipocytes is critical in order to utilize its …

Studies On Root Turion Propagation Technology Of Wild Hazelnut In Daxing'anling, China, Yuliang Liu, Fugui Mi, Puchang Wang

IGC Proceedings (1977-2023)

No abstract provided.

Health Literacy In Students In Queens, Ny, Joohyun Lee, Nitesh Kunda

Journal of Vincentian Social Action

No abstract provided.

Improving Clinician Adherence Rates To Aims Testing On Individuals Taking Long-Term Antipsychotics, Shavaun Johnson

Dissertations

Abstract

Problem: Tardive dyskinesia is a common problem that creates challenges in the lives of those affected by it. The Abnormal Involuntary Movement Scale records the occurrence of tardive dyskinesia in patients receiving neuroleptic medication. With this scale, clinicians can detect tardive dyskinesia and its severity over time. The aim of this study is to learn the current rate of adherence for clinicians at the organization and to create and implement an intervention that will increase that rate in an effort to improve patient outcomes and quality of life.

Methods: This quality improvement project will use a descriptive cohort …

Mitigating Suicide Risk Post-Discharge From Inpatient Crisis Stabilization: Safety Planning Intervention, Leighia M. Mcghee

Dissertations

Abstract

Purpose: The purpose of this program evaluation is to evaluate the effectiveness of a newly implemented safety planning intervention (SPI) tool, comparing patient outcomes relating to suicide attempt rates, emergency department (ED) encounter rates, and inpatient rehospitalizations rates pre and post its integration to care in a suburban behavioral health hospital.

Methods: A descriptive cohort design utilizing a retrospective chart review was completed over six months, three months pre, and three months post implementation of the SPI program. A convenience sample of inpatient charts was reviewed to assess the rate of suicide attempts, ED encounters frequencies, and hospitalization rates …

Free L-Glutamate-Induced Modulation In Oxidative And Neurochemical Profile Contributes To Enhancement In Locomotor And Memory Performance In Male Rats, Saiqa Tabassum, Saara Ahmad, Syeda Madiha, Sidrah Shahzad, Zehra Batool, Sadia Sadir, Saida Haider

Department of Biological & Biomedical Sciences

Glutamate (Glu), the key excitatory neurotransmitter in the central nervous system, is considered essential for brain functioning and has a vital role in learning and memory formation. Earlier it was considered as a harmful agent but later found to be useful for many body functions. However, studies regarding the effects of free L-Glu administration on CNS function are limited. Therefore, current experiment is aimed to monitor the neurobiological effects of free L-Glu in male rats. L-Glu was orally administered to rats for 5-weeks and changes in behavioral performance were monitored. Thereafter, brain and hippocampus were collected for oxidative and neurochemical …

The Effects Of Welfare Time Limits On Access To Financial Resources: Evidence From The 2010s, Gabrielle Pepin

Upjohn Institute Working Papers

The Personal Responsibility and Work Opportunity Reconciliation Act of 1996 established the Temporary Assistance for Needy Families (TANF) program within the United States. TANF mandated 60-month lifetime time limits for federal cash assistance dollars. Because states reserve the right to set their own stricter or more generous time limits, the 60-month lifetime limit did not bind in all cases. In recent years, however, several states imposed TANF time limits for the first time or made existing time limits more stringent. Using administrative and survey data, I find that stricter time limits decrease annual TANF participation by 22 percent and annual …

Coeliac Disease Pathogenesis: The Uncertainties Of A Well-Known Immune Mediated Disorder, Greg Byrne, Margaret Dunne, Con Feighery, Fernando Chirdo

Articles

Coeliac disease is a common small bowel enteropathy arising in genetically predisposed individuals and caused by ingestion of gluten in the diet. Great advances have been made in understanding the role of the adaptive immune system in response to gluten peptides. Despite detailed knowledge of these adaptive immune mechanisms, the complete series of pathogenic events responsible for development of the tissue lesion remains less certain. This review contributes to the field by discussing additional mechanisms which may also contribute to pathogenesis. These include the production of cytokines such as interleukin-15 by intestinal epithelial cells and local antigen presenting cells as …

The Role Of Parent Self-Regulation In Youth Type 1 Diabetes Management., Katherine W Bauer, Marisa E Hilliard, Dana K. Albright Phd, Sharon L Lo, Emily M. Fredericks, Alison L Miller

Health Services and Informatics Research

PURPOSE OF REVIEW: Youth with strong self-regulation (SR), or the ability to manage thoughts, emotions, and behaviors, engage in more effective type 1 diabetes (T1D) management. However, while parent support and engagement are critical to ensuring positive youth T1D outcomes, it is rarely considered that parents' SR may also influence youth T1D management. If this is the case, novel interventions to improve parents' SR or ensure adequate support for parents with SR challenges offer great potential to improve family functioning and youth T1D management.

RECENT FINDINGS: Theoretical and preliminary empirical evidence suggests that parental SR impacts family processes that support …

Spatio-Temporal Dynamics Of Landscape Use By The Bumblebee Bombus Pauloensis (Hymenoptera: Apidae) And Its Relationship With Pollen Provisioning, Pablo Cavigliasso, Colin Phifer, Erika M. Adams, David J. Flaspohler, Gerardo P. Gennari, Julian A. Licata, Natacha P. Chacoff

Michigan Tech Publications, Part 1

Understanding how bees use resources at a landscape scale is essential for developing meaningful management plans that sustain populations and the pollination services they provide. Bumblebees are important pollinators for many wild and cultivated plants, and have experienced steep population declines worldwide. Bee foraging behavior can be influenced by resource availability and bees' lifecycle stage. To better understand these relationships, we studied the habitat selection of Bombus pauloensis by tracking 17 queen bumblebees with radio telemetry in blueberry fields in Entre Ríos province, Argentina. To evaluate land use and floral resources used by bumblebees, we tracked bees before and after …

Socioeconomic And Neuroanatomic Contributions To Language Performance In Children Born Very Preterm At Preschool And School Age, Rebecca E. Avila-Rieger

Psychology ETDs

Background: Children born very preterm are more likely to have difficulties with language acquisition and use that persist throughout childhood. Preterm birth occurs at a critical time in brain development and interrupts neurodevelopment, which has downstream implications for altered neural structure and function. Prematurity and socioeconomic status greatly impact language performance in children, but the neural substrates are poorly understood. Here the neural constituents of language performance are examined in select cortical and subcortical regions.

Methods: Fifty-one children born preterm (24-31 weeks) and 20 born full-term were seen at preschool (mean age = 47 months) and school age (mean age …

Need For Professionals Who Speak A Second Language Greater Than Ever, Shannon Thomason

Browse All News

No abstract provided.

Rsif Weekly Vol.1 No.6, Regional Scholarship And Innovation Fund (Rsif)

Rsif Newsletters

No abstract provided.

Metformin Enhances Autophagy And Normalizes Mitochondrial Function To Alleviate Aging-Associated Inflammation, Leena P Bharath, Madhur Agrawal, Grace Mccambridge, Dequina A Nicholas, Hatice Hasturk, Jing Liu, Kai Jiang, Rui Liu, Zhenheng Guo, Jude Deeney, Caroline M Apovian, Jennifer Snyder-Cappione, Gregory S Hawk, Rebecca M Fleeman, Riley M F Pihl, Katherine Thompson, Anna C Belkina, Licong Cui, Elizabeth A Proctor, Philip A Kern, Barbara S Nikolajczyk

Faculty, Staff and Student Publications

Age is a non-modifiable risk factor for the inflammation that underlies age-associated diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine profiling and bioinformatic analyses showed that Th17 cytokine production differentiates CD4+ T cells from lean, normoglycemic older and younger subjects, and mimics a diabetes-associated Th17 profile. T cells from older compared to younger subjects also had defects in autophagy and mitochondrial bioenergetics that associate with redox imbalance. Metformin ameliorated the Th17 inflammaging profile by increasing autophagy and improving mitochondrial bioenergetics. By contrast, autophagy-targeting siRNA disrupted redox balance in T cells from young subjects and activated the Th17 …