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Isolation, Structure Elucidation, And Synthesis Of Natural Products From Marine Cyanobacteria, Keren Solomon

Electronic Theses and Dissertations

This thesis describes the isolation, structure elucidation, and synthesis of natural products from marine cyanobacteria. A crude extract from a cyanobacterium collected in Curacao showed selective affinity for the dopamine D₅ receptor in a screen against a panel of CNS receptors. Due to the high similarity of the D₅ and D₁ receptor, to date there are no known ligands that differentiate them. Attempts to purify the compound responsible for this affinity led to the isolation of the known compound caylobolide A. A second extract from a cyanobacterium collected in Panama underwent bioassay-guided fractionation and yielded the novel …

Implementing A Loneliness Assessment Tool In An Older Adult Population, Marquette Leach

Doctor of Nursing Practice (DNP) Manuscripts

Abstract

Loneliness is a subjective experience characterized by a profound decrease in the amount and the quality of desired social connectedness. Community-dwelling older adults are particularly vulnerable to loneliness because of age-related changes such as the loss of driving privileges, loss of a spouse, living alone, socioeconomic changes caused by retirement, and a lack of access to meaningful social activities. These factors diminish an older adult’s sense of belonging, the quality of their social relationships, and the degree to which they are socially engaged. Loneliness presents a significant threat not only to the psychosocial wellbeing of older adults, but also …

Therapeutic Potential Of A Ketogenic Diet In The Treatment Of Major Depressive Disorder, Jordan A. Murrin

Masters Theses, 2020-current

Major depressive disorder (MDD) is the second most common mental health condition and a leading cause of disability in the world. It is theorized that MDD develops from a combination of biological, psychological, and social stressors. The condition is typically treated using pharmaceuticals and psychotherapy. However, not all individuals with MDD have access to or choose to use these treatments, or may prefer to incorporate therapeutic lifestyle changes such as exercise, sleep, and healthy eating. Even with treatment, MDD can alter brain structure and function, leading to the development of comorbid mental health and chronic metabolic conditions like obesity, cardiovascular …

Preliminary Investigations On Columbus Grass (Sorghum Almum Parodi) For Fodder In Semi‐Arid Nigeria: Effects Of Nitrogen Fertilizer On Growth Components And Herbage Yield, B. S. Malami, H. M. Tukur, N. B. Ibrahim

IGC Proceedings (1977-2023)

No abstract provided.

Effects Of Water And Nutrient Treatment On Gas Exchange And Water Relations Of Two Casuarina Equisetifolia Clones, Bala Makesh Kumar, Kailash Paliwal

IGC Proceedings (1977-2023)

No abstract provided.

Seasonal Changes Of Mineral Elements In Yak Blood, Herbage And Soil Around Qinghai Lake, X. L. Luo, J. T. Xu, Y. P. Wei, Z. B. Tong, Y. H. Ma, S. M. Chen, Z. J. Ma

IGC Proceedings (1977-2023)

No abstract provided.

Summer Commencement: August 7, 2020, University Of North Dakota

UND Commencement Programs

UND Summer Commencement program from August 7, 2020.

Incorporating Physical Activity Into Your Daily Life, Erin Howie

Diet, Food, Exercise, and Nutrition (D-FEND)

Different forms of physical activity, ways to incorporate physical activity into your daily life, things to consider when choosing a fitness monitor & how to workout safely during COVID-19 pandemic.

Hypoplastic Left Heart Syndrome, Stacey Carey

Nursing Student Class Projects (Formerly MSN)

Hypoplastic left heart syndrome (HLHS) is a severe and rare form of congenital heart disease with no known cause that decreases life expectancy and occurs during fetal cardiac development. Without treatment HLHS is fatal. HLHS consists of the underdevelopment of the left-sided heart structures leading to the failure of the left ventricle to support the systemic circulation resulting in single-ventricle physiology (Mussa & Barron, 2016). Prior to the 1980s HLHS was a universally lethal condition until 1982, when surgical management became available (Mussa & Barron, 2016). However, surgical management is not curative because the heart can never be “normal” (Mussa …

Assessment Of Wild Ring-Tailed Lemur (Lemur Catta) Populations In Southwestern Madagascar With Implications For The Illegal Pet Trade, Samantha D. Calkins

Theses and Dissertations

Accurate population estimates are critical to inform conservation management of species. Incomplete sampling can lead to population underestimates and lacking conservation efforts. Population surveys are important for assessing human and animal welfare to allow for targeted conservation action. Recent ring-tailed lemur (Lemur catta) surveys have led researchers to conclude that L. catta populations are crashing. This has generated much attention and alarm, but may also be based on incomplete information. To better understand population dynamics, more thorough sampling is needed. Here, we survey five such sites to reassess the presence and abundance of L. catta in these locations. …

Genetic Diversity: The Hub Of Plant Breeding, Foster Kangben

International Programs

Agriculture the world over is faced with the threat of food, fiber, and nutrition insecurity especially in the wake of climate change. However, employing two approaches to plant breeding, the molecular and phenotypic methods, can make use of genetic diversity in crop species in order to help surmount these challenges.

Role Of Tannins-Containing Shrub Legume Calliandra Calothyrsus On Rumen Microbes Metabolisms, Firman Nasiu

International Programs

The aim of this study is to evaluate the effect of tannins compound on rumen microbial metabolisms which can be estimated from fermentation parameters including production of VFA (Volatile Fatty Acid), NH₃ and protein microbial in rumen.

The Stakes Of Girls' Education In Senegal, Ndeye Seck

International Programs

No abstract provided.

A Comparison Of The Economic And Cultural Development Of Japan And Thailand Through The Human Development And World Happiness Indices, Tanner Money

Undergraduate Honors Theses

The purpose of this thesis is to make human development and happiness comparisons between two countries that are found in the same region of the world and share similar cultural and historical backgrounds. For this study, the human development measures for Japan and Thailand are compared based on Life Expectancy, Literacy Rates, and Gross Domestic Product (per capita) measures. First, the historical development of Japan and Thailand is presented, highlighting the key historical economic and political moments in each country that has led them to their present state of development. Second, the two countries were compared using quantitative and qualitative …

Consumer Purchasing Response To Mandatory Genetically Engineered Labeling, Elizabeth Macaulay Thomas

Theses and Dissertations

On January 1, 2022, mandatory genetically engineered (GE) food disclosure labeling will be required nationwide in the United States. To date, the only mandatory GE labeling law implemented in the U.S. was Act 120 in Vermont. This thesis examines the consumer purchasing response to the implementation of Vermont Act 120 using store-level scanner data of food purchases. I measure the effects of Vermont Act 120 on the grocery store sales of non-GMO, organic, and GE- labeled products in Vermont. Using a difference-in-difference approach, I can compare stores in Vermont to control states before and after the law was passed, implemented, …

Families In Poverty: Additive And Qualitative Influence Of Risk On Parenting, Lauren Aaron

LSU New Orleans Theses and Dissertations

Co-occurrence of risk for impoverished families is common, but less is known about how compounded risk influences parenting behavior. Mothers (n = 167) and their two-year-old children were visited at home and engaged in a game aimed to elicit everyday parenting behavior. Mothers endorsed experience of sociodemographic and psychosocial risks. Two unique cumulative risk indices were created from these variables. Regression analyses assessed the relation between the risk indices and positive and negative parenting behavior. Latent class analysis examines classes of risk experience on the same indicators. Results show psychosocial risk experience is associated with both parenting factors, while …

Functional Characterization Of Petiolule-Like Pulvinus (Plp) Gene In Abscission Zone Development In Medicago Truncatula And Its Application To Genetic Improvement Of Alfalfa, Juan Du, Shaoyun Lu, Maofeng Chai, Chuanen Zhou, Liang Sun, Yuhong Tang, Jaydeep Kolape, Zhaozhu Wen, Marjan Behzadirad, Tianxiu Zhong, Juan Sun, Yunwei Zhang, Zeng-Yu Wang

Department of Agronomy and Horticulture: Faculty Publications

Alfalfa (Medicago sativa L.) is one of the most important forage crops throughout the world. Maximizing leaf retention during the haymaking process is critical for achieving superior hay quality and maintaining biomass yield. Leaf abscission process affects leaf retention. Previous studies have largely focused on the molecular mechanisms of floral organ, pedicel and seed abscission but scarcely touched on leaf and petiole abscission. This study focuses on leaf and petiole abscission in the model legume Medicago truncatula and its closely related commercial species alfalfa. By analysing the petiolule-like pulvinus (plp) mutant in M. truncatula at phenotypic level (breakstrength and shaking …

Functional Characterization Of Petiolule-Like Pulvinus (Plp) Gene In Abscission Zone Development In Medicago Truncatula And Its Application To Genetic Improvement Of Alfalfa, Juan Du, Shaoyun Lu, Maofeng Chai, Chuanen Zhou, Liang Sun, Yuhong Tang, Jin Nakashima, Jaydeep Kolape, Zhaozhu Wen, Marjan Behzadirad, Tianxiu Zhong, Juan Sun, Yunwei Zhang, Zeng-Yu Wang

Nebraska Center for Biotechnology: Faculty and Staff Publications

Alfalfa (Medicago sativa L.) is one of the most important forage crops throughout the world. Maximizing leaf retention during the haymaking process is critical for achieving superior hay quality and maintaining biomass yield. Leaf abscission process affects leaf retention. Previous studies have largely focused on the molecular mechanisms of floral organ, pedicel and seed abscission but scarcely touched on leaf and petiole abscission. This study focuses on leaf and petiole abscission in the model legume Medicago truncatula and its closely related commercial species alfalfa. By analysing the petiolule-like pulvinus (plp) mutant in M. truncatula at phenotypic level …

Deciphering Type 2 Diabetes-Associated Snp Effects On Islet Chromatin Accessibility And Beta Cell Expression Levels Using Functional Genomics, Shubham Khetan

Doctoral Dissertations

Type 2 diabetes (T2D) results when pancreatic beta cells are unable to secrete adequate amounts of insulin in response to elevated blood glucose levels. Genome-wide association studies (GWAS) have linked single nucleotide polymorphisms (SNPs) in >250 regions of the human genome to a higher risk for developing T2D. These T2D-associated GWAS SNPs are predominantly non-coding (~90%) and enriched at islet regulatory elements, implicating altered transcriptional regulation in islets as a molecular mechanism underlying T2D risk. However, the sharp rise in T2D incidence over the past few decades cannot be attributed to changes in the human genome, but our environment, such …

Con Confianza: Using Community-Based Participatory Research Principles To Inform Community-Academic Partnership Practices And Build Trust In Hispanic Communities, Sharon Tafolla

Master's Projects and Capstones

Hispanic communities are at disproportionate risk for chronic diseases and researchers have cited the need for further community and culturally informed studies to improve research outcomes to either make treatments and interventions more generalizable or modify them to the needs of Hispanic communities. However, many of the same linguistic and cultural barriers to health care access and utilization also impact the ability for Hispanic groups to participate in research studies. Community Academic Partnerships (CAPs) are positioned to conduct culturally and linguistically competent research in Hispanic communities. For research in Hispanic communities to be effective, CAPs must prioritize practices that build …

Chronic Kidney Disease Prevention In The Hispanic/Latino Community: Sf Mission District, Michael Alba Huizar

Master's Projects and Capstones

Chronic kidney disease (CKD) is a growing medical condition that affects many Americans; however, the largest minority group living in the US, Hispanic/Latinos, are suffering the most complications associated with the disease. Multiple research has concluded that due to barriers such as poverty, limited education, and limited English proficiency, it has prevented many Hispanic/Latinos from knowing their disease status. My internship at the Community Health Resource Center was to create a CKD campaign in Spanish that targets the Hispanic/Latino community living in San Francisco's Mission District. As well, the Campaign's goal was to tackle the challenges that prevent Hispanic/Latinos in …

The Vicious Cycle Of Poverty And Unmet Community Health Needs In San Francisco’S Tenderloin (Tl) Neighborhood: Solutions Based On Stakeholder Perceptions, Joya Esagoff

Master's Projects and Capstones

A vicious cycle has arisen in San Francisco’s Tenderloin (TL) neighborhood, in which poverty contributes to significant health disparities, thwarting optimal health outcomes, thus further worsening the underlying poverty which takes on a generational and urban character. TL residents face core socioeconomic and public health challenges with regard to the following themes: access to and coordination of care and services; food security (including healthy eating and active living); housing security; safety from violence and trauma; social, emotional, and behavioral health; poverty; and infrastructure. Essential deficiencies in these domains individually and together worsen the community’s health outcomes. This Capstone examines these …

Emerging Infections: The World Is Not Safe Until Countries Invest In Public Health Infrastructure. A Closer Look At Sub Saharan Africa (Ssa) Public Health Infrastructure During Covid-19 Pandemic., Liziana Nyakubaya

Master's Projects and Capstones

COVID-19 pandemic threatens public health systems across the globe. The ravaging COVID-19 virus does not spare public health systems of large economies such as the US. There are global shortages of PPE, laboratory, and critical care capacity is overwhelmed by the pandemic. Well-resourced public health care infrastructure is essential in reducing mortality, and disease burden in an epidemic, promoting global health security and safeguarding the progress made in other health programs such as HIV/AIDS and TB.

When public health care systems in high-income countries are struggling to manage COVID-19, the situation is worse for under-funded public health systems in SSA. …

Assessing Seasonal Changes In Body Condition For Spotted (Phoca Largha), Ringed (Pusa Hispida), And Bearded (Erignathus Barbatus) Seals, Michelle Hartwick

Master's Theses

Anthropogenic global warming is causing unprecedented changes to occur within Arctic ecosystems. As sea ice continues to decline in both thickness and extent, ice-adapted species will be particularly affected. Specifically, Arctic seals are reliant on sea ice during critical life-history stages and many of their preferred prey depend on reliable patterns in annual sea ice cover. Thus, ongoing changes will likely affect the ability of Arctic seals to carry out key life-history tasks and maintain positive energy balance. One way to assess energy reserves is through examination of body condition. For seals, this is often done by measuring overall blubber …

The Mother-Infant Dyad: Reconstructing Maternal Nutritional Status At Put Dragulina Cemetery, Julianne Marie Paige

Theses and Dissertations

This research investigates maternal nutritional status through the analysis of young infants (N=27) that are likely pre-weaned from two Roman occupational periods at Put Dragulina. Because young infants are solely dependent on the nutritional status of their mother while in utero and postpartum through the consumption of breast milk, the presence of skeletal pathologies positively associated to nutritional deficiencies on the remains of young infants can be analyzed to reconstruct the nutritional status of the infant’s mother. This study finds that 89% (N=24) of young infants, regardless of occupational period, presented with skeletal pathologies consistent with nutritional deficiencies. These results …

Pyritic Lignite As A Source Of Iron For Soybean As Influenced By Variety And Soil Ph., Andrea Paola Elvir Flores

Theses and Dissertations

Iron deficiency chlorosis (IDC) is a frequent problem in soybean [Glycine max (L.) Merr.] production on calcareous soils. Greenhouse and soil incubation experiments were established to evaluate pyritic lignite efficacy to supply Fe as compared to Fe-EDDHA and Fe-EDTA sources across contrasting IDC tolerance varieties grown on a slightly acid and a calcareous soil. Soybean IDC incidence was influenced by the soil properties and variety tolerance. All iron sources increased plant dry matter accumulation on the Leeper soil, whereas on the Marietta soil only lignite at 0.672 kg ha-1 produced an increase. Lignite at 0.336 kg ha-1 successfully improved Fe …

Response Of Male White-Tailed Deer (Odocoileus Virginianus) To Human Activity On The Landscape, Colby Henderson

Theses and Dissertations

Human activity affects white-tailed deer (Odocoileus virginianus) movement and habitat selection during all times of the year, but knowledge is limited regarding how human risk affects white-tailed deer during the summer and winter. During spring and summer, variation in patch selection varied. Natural vegetation was selected for early in the year, with anthropogenic forages being important for deer use during the summer. During the winter, deer responded to different levels of risk. As hunter risk increased on the landscape, deer altered selection of the landscape. Deer avoided areas that were heavily used by hunters, using areas containing less hunter risk. …

Post-Harvest Reduction Of Salmonella In Pork Trimming, Dishnu Sajeev

Theses and Dissertations

The objective of the current study was to determine the efficacy of 3% acetic acid in reducing Salmonella in pork trimming and the effects of such treatment on meat quality. For 15-s dipping and 5-log CFU/pork cube inoculation, only 0.2- to 0.3-log reduction was observed (P ≤ 0.026). Acetic acid worked best at 75 s and 50°C, providing 1.4-log reduction (P < 0.001), damaging Salmonella cell membranes. When an inoculated pork cube was placed at the geometrical center of 2.3-kg pork trimming, dipping at 50°C for 75 s only reduced Salmonella by 0.2 log (P = 0.040). Although dipping slightly increased lightness (P < 0.001) and decreased redness (P ≤ 0.008) on the meat surface, no inside color change was detected (P = 0.120). Neither lipid oxidation (TBARS, P = 0.644), protein solubility (P = 0.187), nor water-holding capacity (P = 0.076) were affected by treatments.

Early Administration Of Probiotics Through In Ovo Inoculation And Their Impact On Gut Microflora, Immune Response, And Growth Performance Of Broiler Chicks, Claudia Duneska Castañeda Bustillo

Theses and Dissertations

Controlling pathogenic presence in broilers has become a priority in the poultry industry to prevent economic losses due to disease and infection, as well as the possible contamination of chicken products. The use of antibiotics reduces the incidence of infections; however, their removal from production initiated the search for suitable alternatives. Probiotic ineed supplements have been widely evaluated as alternatives. Probiotic use has improved broiler performance, reduced pathogenic loads, and stimulated the immune system at later life stages. However, there is still a gap in protection during the first weeks after the chick hatches. The in ovo supplementation of probiotics …

Practitioner Viewpoints On Diet And Inflammatory Bowel Disease, Eytan Ish Stern

Theses and Dissertations

Diet is a key factor in the development and progression of Inflammatory Bowel Disease (IBD). A variety of diets have been studied with IBD patients. This cross-sectional survey identified current healthcare practitioner views on different diets and their efficacy with IBD patients. Diets were rated on awareness, compliance, and contributors to success by participants (n = 181). Frequencies were conducted, and ANOVA with Duncan pairwise comparison or chi-square analysis were used to determine significant differences. Most participants (96%) and 98% of registered dietitians (RD) considered using diet to help treat IBD patients. RDs perceived the low fiber or low residue …