Digital Commons Network^™

Intrarenal Renin Angiotensin System Imbalance During Postnatal Life Is Associated With Increased Microvascular Density In The Mature Kidney, Carolina Dalmasso, Alejandro R. Chade, Mariela Mendez, Jorge F. Giani, Gregory J. Bix, Kuey C. Chen, Analia S. Loria

Hypertension and Vascular Research Articles

Environmental stress during early life is an important factor that affects the postnatal renal development. We have previously shown that male rats exposed to maternal separation (MatSep), a model of early life stress, are normotensive but display a sex-specific reduced renal function and exacerbated angiotensin II (AngII)-mediated vascular responses as adults. Since optimal AngII levels during postnatal life are required for normal maturation of the kidney, this study was designed to investigate both short- and long-term effect of MatSep on (1) the renal vascular architecture and function, (2) the intrarenal renin-angiotensin system (RAS) components status, and (3) the genome-wide expression …

What Will It Take To Implement Health And Health-Related Sustainable Development Goals?, Zulfiqar Ahmed Bhutta, Sameen Siddiqi, Wafa Aftab, Fahad Javaid Siddiqui, Luis Huicho, Roman Mogilevskii, Qamar Mahmood, Peter Friberg, Fawad Akbari

Woman and Child Health

No abstract provided.

Testing Validity Of Fitnessgram In Two Samples Of Us Adolescents (12–15 Years), Eun-Young Lee, Joel D. Barnes, Justin J. Lang, Diego A. S. Silva, Grant R. Tomkinson, Mark S. Tremblay

Education, Health & Behavior Studies Faculty Publications

Background

This study examined the validity of the FitnessGram® criterion-reference cut-points for cardiorespiratory fitness (CRF) based on two samples of US adolescents (aged 12–15 years). This study also established the CRF cut-points for metabolically healthy weight status based on a recent national fitness survey for the purposes of cross-validating with pre-existing cut-points including FitnessGram.

Methods

Two cross-sectional data from the 2003–2004 National Health and Nutrition Examination Survey (NHANES) (n = 378) and 2012 NHANES National Youth Fitness Survey (NNYFS) (n = 451) were used. CRF (estimated V˙" role="presentation" style="box-sizing: border-box; margin: 0px; padding: 0px; display: inline-block; line-height: normal; font-size: 16.2px; …

Mechanisms Of Artemisia Scoparia’S Anti-Inflammatory Activity In Cultured Adipocytes, Macrophages, And Pancreatic Β-Cells, Anik Boudreau, Susan J. Burke, J. Jason Collier, Allison J. Richard, David M. Ribnicky, Jacqueline M. Stephens

Faculty Publications

© 2020 The Obesity Society Objective: An ethanolic extract of Artemisia scoparia (SCO) improves adipose tissue function and reduces negative metabolic consequences of high-fat feeding. A. scoparia has a long history of medicinal use across Asia and has anti-inflammatory effects in various cell types and disease models. The objective of the current study was to investigate SCO’s effects on inflammation in cells relevant to metabolic health. Methods: Inflammatory responses were assayed in cultured adipocytes, macrophages, and insulinoma cells by quantitative polymerase chain reaction, immunoblotting, and NF-κB reporter assays. Results: In tumor necrosis factor α–treated adipocytes, SCO mitigated ERK and NF-κB …

Maternal Gestational Diabetes Mellitus Modifies The Relationship Between Genetically Determined Body Mass Index During Pregnancy And Childhood Obesity, Zhaoxia Liang, Huikun Liu, Leishen Wang, Qiying Song, Dianjianyi Sun, Weiqin Li, Junhong Leng, Ru Gao, Gang Hu, Lu Qi

Population and Public Health Science Faculty Publications

Objective: To analyze the interactions between maternal gestational diabetes mellitus (GDM) and genetically determined maternal body mass index (BMI) during pregnancy on offspring childhood obesity. Research Design and Methods: A total of 1114 Chinese mother-child pairs (560 GDM and 554 non-GDM) were included between August 2009 and July 2011. Maternal genetic risk score (GRS) of BMI during pregnancy was derived on the basis of 12 single nucleotide polymorphisms identified from a genome-wide association study. Offspring's BMI, BMI-for-age z score, weight, weight-for-age z score, waist circumference, sum of skinfolds, and body fat percentage during childhood were measured or calculated. Results: Maternal …

Room Indirect Calorimetry Operating And Reporting Standards (Ricors 1.0): A Guide To Conducting And Reporting Human Whole-Room Calorimeter Studies, Kong Y. Chen, Steve Smith, Eric Ravussin, Jonathan Krakoff, Guy Plasqui, Shigeho Tanaka, Peter Murgatroyd, Robert Brychta, Christopher Bock, Elvis Carnero, Paul Schoffelen, Yoichi Hatamoto, Corey Rynders, Edward L. Melanson

Clinical Research Faculty Publications

Whole-room indirect calorimeters have been used to study human metabolism for more than a century. These studies have contributed substantial knowledge to the assessment of nutritional needs and the regulation of energy expenditure and substrate oxidation in humans. However, comparing results from studies conducted at different sites is challenging because of a lack of consistency in reporting technical performance, study design, and results. In May 2019, an expert panel was convened to consider minimal requirements for conducting and reporting the results of human whole-room indirect calorimeter studies. We propose Room Indirect Calorimetry Operating and Reporting Standards, version 1.0 (RICORS 1.0) …

The Design Of A Randomized Clinical Trial To Evaluate A Pragmatic And Scalable Ehealth Intervention For The Management Of Gestational Weight Gain In Low-Income Women: Protocol For The Smartmoms In Wic Trial, Emily W. Flanagan, Abby D. Altazan, Natalie R. Comardelle, L. Anne Gilmore, John W. Apolzan, Jessica St. Romain, Julie C. Hardee, Renee S. Puyau, Christy L. Mayet, Robbie A. Beyl, S. Ariel Barlow, Sarah Surber Bounds, Kelsey N. Olson, Betty M. Kennedy, Daniel S. Hsia, Leanne M. Redman

Clinical Research Faculty Publications

Background: Less than one-third of women gain an appropriate amount of weight during pregnancy, which can influence the long-term health of both the mother and the child. Economically disadvantaged women are the most vulnerable to maternal obesity, excessive weight gain during pregnancy, and poor birth outcomes. Effective and scalable health care strategies to promote healthy weight gain during pregnancy specifically tailored for these women are lacking. Objective: This paper presents the design and protocol of a biphasic, community-based eHealth trial, SmartMoms in WIC, to increase the adherence to healthy gestational weight gain (GWG) recommendations in low-income mothers receiving women, infant, …

Biological Aging In Childhood And Adolescence Following Experiences Of Threat And Deprivation: A Systematic Review And Meta-Analysis, Natalie L. Colich, Maya L. Rosen, Eileen S. Williams, Katie A. Mclaughlin

Neuroscience: Faculty Publications

Life history theory argues that exposure to early life adversity (ELA) accelerates development, although existing evidence for this varies. We present a meta-analysis and systematic review testing the hypothesis that ELA involving threat (e.g., violence exposure) will be associated with accelerated biological aging across multiple metrics, whereas exposure to deprivation (e.g., neglect, institutional rearing) and low-socioeconomic status (SES) will not. We meta-analyze 54 studies (n = 116,010) examining associations of ELA with pubertal timing and cellular aging (telomere length and DNA methylation age), systematically review 25 studies (n = 3,253) examining ELA and neural markers of accelerated development (cortical thickness …

Integrated Learning Programme Guidebook : Term 1, 2020/21, Student Services Centre

ILP Guidebook

This Integrated Learning Programme (ILP) guidebook provides details about ILP courses offered during 2020-2021 first term in Lingnan University, Hong Kong.

Identification Of Pathways Associated With Placental Adaptation To Maternal Nutrient Restriction In Sheep, Ashley K. Edwards, Kathrin A. Dunlap, Thomas E. Spencer, M. Carey Satterfield

Faculty Publications

Maternal nutrient restriction impairs placental growth and development, but available evidence suggests that adaptive mechanisms exist, in a subset of nutrient restricted (NR) ewes, that support normal fetal growth and do not result in intrauterine growth restriction (IUGR). This study utilized Affymetrix GeneChip Bovine and Ovine Genome 1.0 ST Arrays to identify novel placental genes associated with differential fetal growth rates within NR ewes. Singleton pregnancies were generated by embryo transfer and, beginning on Day 35 of pregnancy, ewes received either a 100% NRC (control-fed group; n = 7) or 50% NRC (NR group; n = 24) diet until necropsy …

Synergisms In Science: Climate Change And Integrated Pest Management Through The Lens Of Communication-2019 Student Debates, Jocelyn R. Holt, Lina Bernaola, Kadie E. Britt, Chirs Mccullough, Morgan Roth, Jennie Wagner, Max Ragozzino, Leslie Aviles, Zhilin Li, Forest Huval, Manoj Pandey, Benjamin W. Lee, Megan Asche, Abigail Hayes, Abigail Cohen, Adrian Marshall, Hannah E. Quellhorst, Rachel V. Wilkins, Valerie Nguyen, Jacqueline Maille, Rachel K. Skinner, John J. Ternest, Sarah Anderson, Scott W. Gula, Kayleigh Hauri, Julius Eason, Megan Mulcahy, Scott Lee, James Michael Villegas, Patricia Shorter

Faculty Publications

Every year, the Student Debates Subcommittee (SDS) of the Student Affairs Committee (SAC) for the annual Entomological Society of America (ESA) meeting organizes the Student Debates. This year, the SAC selected topics based on their synergistic effect or ability to ignite exponential positive change when addressed as a whole. For the 2019 Student Debates, the SAC SDS identified these topic areas for teams to debate and unbiased introduction speakers to address: 1) how to better communicate science to engage the public, particularly in the area of integrated pest management (IPM), 2) the influential impacts of climate change on agriculturally and …

Multiple Decrement Life Tables Of Cephus Cinctus Norton (Hymenoptera: Cephidae) Across A Set Of Barley Cultivars: The Importance Of Plant Defense Versus Cannibalism, Buddhi B. Achhami, Robert K.D. Peterson, Jamie D. Sherman, Gadi V.P. Reddy, David K. Weaver

Faculty Publications

Accurately estimating cause-specific mortality for immature insect herbivores is usually difficult. The insects are exposed to abiotic and biotic mortality factors, causing cadavers to simply disappear before cause of mortality can be recorded. Also, insect herbivores are often highly mobile on hosts, making it difficult to follow patterns for individuals through time. In contrast, the wheat stem sawfly, Cephus cinctus Norton, spends its entire egg, larval, and pupal period inside a host stem. Therefore, with periodic sampling stage-specific causes of mortality can be ascertained. Consequently, we examined C. cinctus mortality in eight barley, Hordeum vulgare L., cultivars in two locations …

Antixenosis, Antibiosis, And Potential Yield Compensatory Response In Barley Cultivars Exposed To Wheat Stem Sawfly (Hymenoptera: Cephidae) Under Field Conditions, Buddhi B. Achhami, Gadi V.P. Reddy, Jamie D. Sherman, Robert K.D. Peterson, David K. Weaver

Faculty Publications

Wheat stem sawfly, Cephus cinctus Norton, is an economically serious pest of cereals grown in North America. Barley cultivars were previously planted as resistant crops in rotations to manage C. cinctus, but due to increasing levels of injury to this crop, this is no longer a valid management tactic in Montana. Therefore, we aimed to understand antixenosis (behavioral preference), antibiosis (mortality), and potential yield compensation (increased productivity in response to stem injuries) in barley exposed to C. cinctus. We examined these traits in eight barley cultivars. Antixenosis was assessed by counting number of eggs per stem and antibiosis was assessed …

The Validity, Time Burden, And User Satisfaction Of The FoodimageTm Smartphone App For Food Waste Measurement Versus Diaries: A Randomized Crossover Trial, Brian E. Roe, Danyi Qi, Robbie A. Beyl, Karissa E. Neubig, Corby K. Martin, John W. Apolzan

Faculty Publications

© 2020 Elsevier B.V. The FoodImageTM smartphone app transmits users’ photographs of food selection and food waste to researchers, and includes user-tagged information about waste reasons and destination. Twenty-four participants were trained to record food waste using FoodImage, food waste diaries requiring visual estimation of waste quantities, and diaries requiring scale weights. Participants used each method during three staged food-waste scenarios (food preparation, eating, and clean-out) in a randomized crossover trial. Two participants had extreme values for the weighed diary method; therefore, accuracy results are reported with and without these two participants’ data. Error was calculated as waste estimated with …

Unpacking The Decline In Food Waste Measured In Chinese Households From 1991 To 2009, Danyi Qi, John W. Apolzan, Ran Li, Brian E. Roe

Faculty Publications

© 2020 Elsevier B.V. Food waste reduction is an explicit goal for many countries, yet a paucity of high-quality primary measurements of food waste are available to inform policy. We analyze repeated physical measurements of discarded food from more than 37,000 households enrolled in the China Health and Nutrition Survey (CHNS) from 1991 to 2009 and describe relevant food waste patterns and trends within households over a period of dramatic change. Over a period in which average real household incomes tripled, food discarded per person declined by about 20% on a quantity basis and by about 40% on a Calorie …

Obesity, Noncommunicable Diseases, And Covid-19: A Perfect Storm, Peter T. Katzmarzyk, J. Michael Salbaum, Steven B. Heymsfield

Division of Basic Science Faculty Publications

No abstract provided.

Assessment Of Energy Expenditure: Are Calories Measured Differently For Different Diets?, Guillermo Sanchez-Delgado, Eric Ravussin

Clinical Research Faculty Publications

Purpose of review The prevalence and burden of obesity has reached alarming levels. The assessment of human energy expenditure enables the identification of obesity-prone and obesity-resistant individuals and helps to explain the short and long-term success of weight loss treatments. In this review, we describe the state-of-the-art methods used in the assessment of human energy expenditure and the impact of dietary intake on the interpretation of the data. Recent findings The reference techniques to assess energy expenditure in humans have not significantly changed during the last century. Today, indirect calorimetry, either using a metabolic chamber or a metabolic cart, is …

Integrative And Quantitative Bioenergetics: Design Of A Study To Assess The Impact Of The Gut Microbiome On Host Energy Balance, Karen D. Corbin, Rosa Krajmalnik-Brown, Elvis A. Carnero, Christopher Bock, Rita Emerson, Bruce E. Rittmann, Andrew K. Marcus, Taylor Davis, Blake Dirks, Zehra Esra Ilhan, Catherine Champagne, Steven R. Smith

Population and Public Health Science Faculty Publications

The literature is replete with clinical studies that characterize the structure, diversity, and function of the gut microbiome and correlate the results to different disease states, including obesity. Whether the microbiome has a direct impact on obesity has not been established. To address this gap, we asked whether the gut microbiome and its bioenergetics quantitatively change host energy balance. This paper describes the design of a randomized crossover clinical trial that combines outpatient feeding with precisely controlled metabolic phenotyping in an inpatient metabolic ward. The target population was healthy, weight-stable individuals, age 18–45 and with a body mass index ≤30 …

Obesity, The Most Common Comorbidity In Sars-Cov-2: Is Leptin The Link?, Candida J. Rebello, John P. Kirwan, Frank L. Greenway

Division of Basic Science Faculty Publications

Overweight and obesity are major risk factors for diabetes, cardiovascular disease, and lung disease. These diseases are the most commonly reported health conditions that predispose individuals with SARS-CoV-2 infection to require hospitalization including intensive care unit admissions. The innate immune response is the host’s first line of defense against a human coronavirus infection. However, most coronaviruses are armed with one strategy or another to overcome host antiviral defense, and the pathogenicity of the virus is related to its capacity to suppress host immunity. The multifaceted nature of obesity including its effects on immunity can fundamentally alter the pathogenesis of acute …

Selection, Intake, And Plate Waste Patterns Of Leftover Food Items Among U.S. Consumers: A Pilot Study, Brian E. Roe, Danyi Qi, John W. Apolzan, Corby K. Martin

Clinical Research Faculty Publications

Many campaigns promote the preservation and consumption of leftover food items as a critical household strategy to accomplish national consumer food waste reduction goals. We fill a gap in knowledge about the consumption and creation of leftovers in the United States by analyzing data from a pilot study in which 18 subjects tracked food selection, intake, and plate waste across all eating occasions for about one week. Subjects noted which items selected for consumption were leftovers, i.e., previously prepared but uneaten items that were stored for future consumption, and which unfinished items were saved to become leftovers. We found that …

Effectiveness Of Aqueous Chlorine Dioxide In Minimizing Food Safety Risk Associated With Salmonella, E. Coli O157:H7, And Listeria Monocytogenes On Sweet Potatoes, Phillip Luu, Vijay Singh Chhetri, Marlene E. Janes, Joan M. King, Achyut Adhikari

Faculty Publications

Sodium hypochlorite (NaOCl) is a commonly used sanitizer in the produce industry despite its limited effectiveness against contaminated human pathogens in fresh produce. Aqueous chlorine dioxide (ClO2) is an alternative sanitizer offering a greater oxidizing potency with greater efficacy in reducing a large number of microorganisms. We investigated the effect of aqueous chlorine dioxide treatment against human pathogens, Salmonella, Escherichia coli O157:H7, and Listeria monocytogenes seeded on sweet potatoes. Sweet potatoes were spot inoculated (4.2 to 5.7 log CFU/cm2) with multi-strain cocktails of Salmonella spp., E. coli O157:H7, and L. monocytogenes and treated for 10-30 min with 5 ppm aqueous …

Population Structure Analysis And Identification Of Genomic Regions Under Selection Associated With Low-Nitrogen Tolerance In Tropical Maize Lines, Gustavo César Sant'ana, Fernando Garcia Espolador, Ítalo Stefanine Correia Granato, Leandro Freitas Mendonça, Roberto Fritsche-Neto, Aluízio Borém

Faculty Publications

Increasing low nitrogen (N) tolerance in maize is an important goal for food security and agricultural sustainability. In order to analyze the population structure of tropical maize lines and identify genomic regions associated with low-N tolerance, a set of 64 inbred lines were evaluated under low-N and optimal-N conditions. The low-N Agronomic Efficiency index (LNAE) of each line was calculated. The maize lines were genotyped using 417,112 SNPs markers. The grouping based on the LNAE values classified the lines into two phenotypic groups, the first comprised by genotypes with high LNAE (named H_LNAE group), while the second one comprised genotypes …

Teachers, Students, And Lessons Learned

In Case You Missed It

SEPTEMBER 2020

Methods For Using Nhanes For Exposure Estimates, Heather R. Campbell, Robert A. Lodder

Pharmaceutical Sciences Faculty Publications

The National Health and Nutrition Examination Survey (NHANES) is a scheme of studies with the objective of measuring the health and nutritional status of adults and children in the United States. The survey is unique in that it has a clinical component (NCT00005154), and combines interviews and physical examinations into its data sets. NHANES is an important program of the National Center for Health Statistics (NCHS). NCHS is a unit of the Centers for Disease Control and Prevention (CDC) and has the responsibility for producing vital and health statistics for the United States. Data from the NHANES studies …

It's The Little Things: A Community Resource For Strengthening Social Connections, Caitlin Coyle, Shayna Gleason, Cindy Bui

Center for Social and Demographic Research on Aging Publications

Now, more than ever, it is imperative that we prioritize connection for ourselves and the people around us. The global COVID-19 pandemic and the national reckoning with systemic racism has made people more aware and appreciative of their relationships and has made some painfully aware of how distant and disconnected they are. While the evidence is clear that social isolation is bad for health and well-being, the evidence base of solutions is far less so. Thus, this report sought to harness the energy, creativity, and progressive thinking of cities and towns in Massachusetts by documenting their efforts to keep people …

Building Implementation Science In Nutrition, Andrea M. Warren, Edward A. Frongillo Jr., Rahul Rawat

Faculty Publications

The field of nutrition has been investing in the development of many nutrition-specific and -sensitive policies and programs aimed at improving population-level malnutrition in all its forms. When there is a need to learn about a new system, programmatic context, or target population to understand how to effectively deploy an intervention to help improve nutrition, it is important to be able to ask a broad range of questions, both in topic and in scope. Our aim is to provide a simple and conceptually clear definition and principles to elaborate the science of implementation for nutrition to distinguish it from other …

Data Management Report September 2020, Tennessee. Department Of Intellectual And Developmental Disabilities

Compliance & System Data/Reports

This monthly report provides data on various aspects of the department's activities and programs.

Bioo 320.B01: General Botany, Marilyn Marler

University of Montana Course Syllabi

No abstract provided.

Biob 524.01: Physiological Plant Ecology, Anna Sala

University of Montana Course Syllabi

No abstract provided.

Writ 201.51: Intermediate College Writing Ii - Writing The Body: The Rhetoric Of Health And Illness (Online), Erik Norbie

University of Montana Course Syllabi

No abstract provided.