Digital Commons Network^™

Proprotein Convertase Subtilisin/Kexin Type-9 (Pcsk-9) Inhibitors Induced Liver Injury - A Retrospective Analysis., Yousuf Zafar, Yasar Sattar, Waqas Ullah, Sohaib Roomi, Mamoon-Ur- Rashid, Muhammad Shayan Khan, Laura Schmidt

Abington Jefferson Health Papers

Background: Proprotein convertase subtilisin/Kexin type 9 (PCSK-9) inhibitors induced liver dysfunction in patients with or without previous liver injury, and this is not well discussed in the previous literature.

Methods: A total sample of 202 patients were retrospectively reviewed at the University of Missouri, Kansas City, from the year 2015 to 2018 based on predefined selection criteria. Inclusion criteria involved patients with dyslipidemia, with or without PCSK-9 inhibitors, liver function tests and lipid profile at baseline and at a mean of 6-month follow-up. The variables, including age, gender, and confounding factors like other medications (statin, oral antidiabetic, and antihypertensive) induced, …

Implementing Welfare Science: Case Studies In Evidence-Based Zoo Management, Marisa Suzanne Spain

UNF Graduate Theses and Dissertations

Animal welfare science is a field that focuses on how we can improve the lives and well-being of animals in human care. Modern welfare science has moved away from simply preventing suffering and on to promoting positive welfare states, a concept that has been coined animal “wellness”. A process called evidence-based zoo management has been implemented in many zoos as a way to promote and ensure wellness. This is the idea that husbandry and housing standards should be evaluated and tested for their efficacy using data rather than relying on traditional best practices. In this manuscript we discuss an informal …

Nebraska Annual Social Indicators Survey (Nasis) 2020 Winter Methodology Report, Bureau Of Sociological Research

Nebraska Annual Social Indicators Survey (NASIS)

No abstract provided.

Breastfeeding Practices 2008–2009 Among Chinese Mothers Living In Ireland: A Mixed Methods Study, Qianling Zhou, Katherine Younger, Tanya M. Cassidey, Wenyi Wang, John Kearney

Articles

Background

Migration to another country has a potential influence on breastfeeding practices. A significant difference in breastfeeding rates between Irish nationals and non-nationals has been reported. This study was conducted to explore breastfeeding practices of the Chinese in Ireland, one of the largest Irish ethnic groups, and to explore the influence of living in Ireland on breastfeeding practices. This is the first and the only migration study so far on breastfeeding practices among the Chinese in Ireland.

Methods

A sequential explanatory mixed methods approach was adopted. The first phase was a cross-sectional self-administered retrospective mailed survey, to explore breastfeeding practices …

The Prevalence Of Overweight And Obesity In Irish Children Between 1990 And 2019, Aisling O'Donnell, Maria Buffini, Laura Kehoe, Ann Nugent, John Kearney, Janette Walton, Albert Flynn, Breige Mcnulty

Articles

Objective: The present study aimed to examine the temporal prevalence of overweight and obesity in Irish children through different methodologies and evaluate the change in rates between 1990 and 2019.

Resource Selection And Calving Success Of Moose In Colorado, Forest P. Hayes

Graduate Student Theses, Dissertations, & Professional Papers

Across much of North America, moose populations (Alces alces) are declining due to disease, predation, climate, and anthropogenic pressures. Despite this, populations of moose in Colorado have continued to grow. Studying successful (i.e., persistent or growing) populations of moose can facilitate the continued conservation of the species by identifying habitat features critical for moose persistence.

First, I evaluated calving success of moose in Colorado and the impact of willow habitat quality and nutrition. I then estimated the probability of female moose having a calf using repeated observations in a Bayesian occupancy model. I assigned values for dry matter …

Gvsu Undergraduate And Graduate Catalog, 2020-2021, Grand Valley State University

Course Catalogs, 1963 - Current

Grand Valley State University 2020-2021 undergraduate and graduate course catalog. Course catalogs are published annually to provide students with information and guidance for enrollment.

Sex And Age Differences In Prevalence And Risk Factors For Prediabetes In Mexican-Americans, Kristina Vatcheva, Belinda M. Reininger, Susan P. Fisher-Hoch, Joseph B. Mccormick

School of Mathematical & Statistical Sciences Faculty Publications

AIMS:

Over 1/3 of Americans have prediabetes, while 9.4% have type 2 diabetes. The aim of our study was to estimate the prevalence of prediabetes in Mexican Americans, with known 28.2% prevalence of type 2 diabetes, by age and sex and to identify critical socio-demographic and clinical factors associated with prediabetes.

METHODS:

Data were collected between 2004 and 2017 from the Cameron County Hispanic Cohort in Texas. Weighted crude and sex- and age- stratified prevalences were calculated. Survey weighted logistic regression analyses were conducted to identify risk factors for prediabetes.

RESULTS:

The prevalence of prediabetes (32%) was slightly higher than …

Collection Weeding: Innovative Processes And Tools To Ease The Burden, Gregory M. Nelson, Michael C. Goates, David S. Pixton, Megan Frost, Dan Broadbent

Faculty Publications

Evaluating collections and ultimately removing content poses a variety of difficult issues, including choosing appropriate deselection criteria, communicating with stakeholders, providing accountability, and managing the overall timetable to finish projects on time. The Science and Engineering librarians at Brigham Young University evaluated their entire print collection of over 350,000 items within one year, significantly reducing the number of items kept on the open shelves and the physical collection footprint. Keys to accomplishing this project were extensive preparation, tracking progress and accountability facilitated by Google Sheets and an interactive GIS stacks map, and stakeholder feedback facilitated by a novel web-based tool. …

Identifying Gaps In Care: Assessment Of Ancillary Support Service Utilization For Lower Extremity Amputees At A Large Tertiary Care Center, Ryan Johnson, James J. Goodreau Md

USF-LVHN SELECT

No abstract provided.

Socio-Economic Burden Of Malaria: The Case Of Jabi-Tehnan Distric, Getaneh Mihret

All Master’s Theses

This thesis explores the economic burden of malaria incidence by controlling household practices regarding malaria prevention in Jabi-tehnan District. It uses household survey data collected by the Social Sciences and Impact Assessment Unit of the International Centre of Insect Physiology and Ecology(icipe). This study aimed at assessing and examining factors contributing to malaria and the impact of the incidenceby using both descrptive statistics and econometrics aproach. In the descriptive analysis, itis assessed that malaria causes on average 465 ETBexpenditure per person, led to 29 days of absenteeism from school, and 10 workdays lost. We use OLS and RE for malaria …

Evaluation Of Modified Collection Drums And Light Emitting Diode Bulbs For Trapping The Edible Long-Hornedgrasshopper, Ruspolia Differens (Serville) In Uganda, Francis Sengendo

All Master’s Theses

The long-horned grasshopper (Ruspolia differens) is a delicacy in Uganda and many African countries. It is traditionally trapped at night during the swarming seasons using mercury bulbs that consume a lot of electric energy and pollute the environment. In addition, thecollection drums used in the traditional trappingtechnique are non-selective,trapping non-target insects, some of which are allergenic to humans. Further, these traps areinefficient in retaining the insects.The International Centre of Insect Physiology and Ecology designed amodified R. differens collection drum by fitting a funnel to minimize escape of R. differens catches; and partitioningthe drum into three compartments using meshes of varying …

Research And Innovation As A Catalyst For Food System Transformation, A.C.L. Den Boer, K.P.W. Kok, M. Gill, J. Breda, Jean Cahill, C. Callenius, P. Caron, Z. Damianova, M. Gurinovic, L. Lahteenmaki, T. Lang, R. Sonnino, G. Verburg, H. Westhoek, T. Cesuroglu, B.J. Regeer, J.E.W. Broerse

Research and Innovation - Other

Background Food systems are associated with severe and persistent problems worldwide. Governance approaches aiming to foster sustainable transformation of food systems face several challenges due to the complex nature of food systems.

Scope and approach In this commentary we argue that addressing these governance challenges requires the development and adoption of novel research and innovation (R&I) approaches that will provide evidence to inform food system transformation and will serve as catalysts for change. We first elaborate on the complexity of food systems (transformation) and stress the need to move beyond traditional linear R&I approaches to be able to respond to …

Research And Innovation Supporting The Farm To Fork Strategy Of The European Commission, R. Sonnino, C. Callenius, L. Lahteenmaki, J. Breda, Jean Cahill, P. Caron, Z. Damianova, M.A. Gurinovic, T. Lang, A. Laperriere, C. Mango, J. Ryder, G. Verbrugh, T. Achterbpscj, A.C.L. Den Boer, K.P.W. Kok, B.J. Regeer, J.E. Broerse, J.E.W. Cesuroglu, T. Gill

Research and Innovation - Other

No abstract provided.

An Investigation Into The Prospective Effects Of Vitamin D Supplementation On The Development & Attenuation Of Non-Alcoholic Fatty Liver Disease, Gage Fink

Research Papers

The purpose of this study is to shed light on the potential role of vitamin D in its hydroxylated form, 25-OH-Cholecalciferol(25OHD), in moderating the development and attenuation of non-alcoholic fatty liver disease (NAFLD) via an aged laying hen model. Specifically, thirty-month-old single-comb white Leghorn hens were assigned at random to one of three diets: a control diet (CON) consisting of a standard composition of feed and supplements, a vitamin-D-supplemented group (VID) consisting of the CON diet with an additional 69 μg/kg of 25OHD per day, and a whole flaxseed (WFX) supplemented group used as a comparative intervention standard against the …

Reducing Meat Consumption: Drawing On Participatory Action Research To Explore Ways Of Engaging In A Process Of Meat Consumption Reduction, Brittany Spadafore

Theses and Dissertations (Comprehensive)

With growing attention to climate change and human impacts on the environment, an emerging body of literature is exploring the impacts of global reliance on meat consumption. Research is increasingly supporting the feasibility of reducing meat consumption to address the environmental pressures of the global food system. However, recommended strategies to promote a reduction in meat consumption have been limited due to narrowly focusing on individual rational decision-making models. Centralizing a Social Practice theoretical lens, the present study utilized an approach to participatory action research to explore the experiences of seven (N = 7) green-building tenants reducing their meat consumption …

Examining Disability In The Region Of Waterloo: Physical Activity Programming And Caregiving, Nicole J. Reinders Luymes

Theses and Dissertations (Comprehensive)

Physical activity (PA) is a necessary component of wellbeing for individuals with and without disabilities. Disabled young people experience many barriers to PA, resulting in inactive lifestyles that compound health issues and hinder their full participation in schools and communities. The following dissertation includes a literature review regarding the effects of PA for young people with a variety of developmental disabilities, in addition to three research studies examining community-based PA programming, and one study exploring the lived experiences of caregivers, all within the Region of Waterloo.

The first study was a needs assessment to examine PA perceptions, practices, barriers, and …

Attitudes Toward The Hpv Vaccine Among University Students: Identifying Barriers To Vaccine Uptake, Kristina L. Harbaugh

College of Graduate Studies: Theses & Dissertations

Background: In the United States, the Centers for Disease Control and Prevention (CDC) estimates that 32,000 cancers occur annually that can be directly attributable to the acquisition of the Human Papilloma Virus (HPV). Gender specificity data posits that 21,000 of the annual cancer cases are female and the remaining 11,000 cases occur among males. However, because the implementation and trajectory of HPV vaccination and prevention programs have been historically aimed toward women, vaccination rates for men remain significantly lower. The purpose of this study was to assess gender differences in knowledge attitude, subjective norms and perceived behavioral control about HPV …

Athletic Identity And Intention To Report Concussions In High School Athletes, Natalie F. Cook

College of Graduate Studies: Theses & Dissertations

Context: Lack of concussion reporting remains a problem as high school athletes report about fifty percent of all concussions. Purpose: The study sought to determine if there is a relationship between athletic identity and athlete’s intention to report concussions. Methods: The sample consisted of 78 high school athletes (m age = 16.19 + 0.88, 56 males, 22 females). Participants were administered the Athletic Identity Measurement Scale (AIMS) and Intention to Report Subscale which served as dependent measures. The presence of AI was determined by comparing AIMS score to previous norms. A linear regression was used to determine the relationship …

Surfacant Contamination Alters Freshwater Phytoplankton Community Composition, William H. Hodge

College of Graduate Studies: Theses & Dissertations

Pollution from cleaning and personal care products enter freshwater systems and have the potential to alter phytoplankton abundance and diversity. Alkyl polyglucoside (APG), a widely used foaming agent in detergents, decreases phytoplankton abundance, but whether sensitivity to APG is affected by taxonomic identity and/or the presence of competitors is unclear. Establishing taxon-specific responses to APG is important, because taxa differ in nutritional quality and palatability for zooplankton grazers.

Chapter one describes comparisons between how individual phytoplankton communities respond to the same range of APG concentrations to test hypotheses that: 1) chemical concentration determines how individual taxa respond to APG; 2) …

Understanding The Context And Social Processes That Shape Person- And Family-Centered Culture In Long-Term Care: The Pivotal Role Of Personal Support Workers, Ellen Helena Melis

Antioch University Dissertations & Theses

This single, exemplar case study explored the context and social processes that shape person-and family-centered culture in a long-term care (LTC) home, using grounded theory and situational analysis for the data collection and analysis. Findings revealed one core dimension: needing to be heard, valued, and understood, and five key roles: personal support workers (PSWs), executive director (ED), senior leadership, nurse managers, and residents and families, which informed five dimensions, each focused on enhancing care for residents: (a) attending to residents’ daily care needs (PSWs), (b) advocating strategically (ED), (c) translating vision into programs and policies (senior leadership), (d) ensuring quality …

Characterization Of Antimicrobial Effects Of Plasma-Treated Water (Ptw) Produced By Microwave-Induced Plasma (Midiplexc) On Pseudomonas Fluorescens Biofilms, Oliver Handorf, Viktoria Isabella Pauker, Thomas Weihe, Eric Freund, Sander Bekeschus, Katharina Riedel, Uta Schnabel, Jörg Ehlbeck

Articles

stract: For the decontamination of surfaces in the food production industry, plasma generated compounds (PGCs) such as plasma-treated water (PTW) or plasma processed air (PPA) offer many promising possibilities for future applications. Therefore, the antimicrobial effect of water treated with microwave-induced plasma (MidiPLexc) on Pseudomonas fluorescensbiofilms was investigated. 10 ml deionized water was treated with the MidiPLexc plasma source for 100 s, 300 s and 900 s (pre-treatment time) and the bacterial biofilms were exposed to the PTW for 1 min, 3 min and 5 min (post treatment time). To investigate the influence of PTW on P. fluorescensbiofilms, microbiological assays …

Effect Of Atmospheric Cold Plasma On The Functional Properties Of Whole Wheat (Triticum Aestivum L.) Grain And Wheat Flour, Sonal Chaple, Chaitanya Sarangapani, John B. Jones, Ed Carey, Lucie Causeret, Annaik Genson, Brendan Duffy, Paula Bourke

Articles

Atmospheric cold plasma (ACP) has emerged as a novel processing technology, with demonstrated efficiencies in microbial inactivation. However, studies on the effects of ACP and potential to modify the functional properties of foods are sparse. The objective of this study is to determine the effect of ACP on physico-chemical and functional properties of wheat flour. In this study, both whole wheat grains and wheat flour were subjected to a dielectric barrier discharge (DBD) contained plasma reactor for a range of treatment times (5–30 min) at 80 kV. Plasma treatment increased the flour hydration properties of wheat flour. Rapid visco-analyser results …

Effects Of Cold Atmospheric Plasma On Mackerel Lipid And Protein Oxidation During Storage, Juan M. Pérez-Andrés, María De Alba, Sabine M Harrison, Nigel P. Brunton, Patrick J. Cullen, Brijesh K. Tiwari

Articles

The present study investigated the effects of cold atmospheric plasma on the shelf-life stability of lipids andproteins of commercially packaged mackerelfillets. The results showed no significant effects on lipid oxidationbetween the control samples and those treated at 80 kV for extended treatment times of 5 min using an in-package plasma system. In addition, no significant changes (p > 0.05) were found in the fatty acid compositionor nutritional quality indices after treatment. Finally, the formation of carbonyls was accelerated by plasmatreatment at the end of the storage period for 4 °C and 8 °C. These results suggest that cold atmospheric plasmatechnologies are …

Food Security And Diet Quality In Native Hawaiian, Pacific Islander, And Filipino Infants 3 To 12 Months Of Age, Sally Campbell, John J. Chen, Carol J. Boushey, Heather Eicher-Miller, Fengqing Zhu, Marie K. Fialkowski

Articles

Food insecurity and other nutritional risks in infancy pose a lifelong risk to wellbeing; however, their effect on diet quality in Native Hawaiian, Pacific Islander, and Filipino (NHPIF) infants in Hawai‘i is unknown. In this cross-sectional analysis, the association between various indicators of food security and NHPIF infant diet quality were investigated in 70 NHPIF infants aged 3–12 months residing on O‘ahu, Hawai‘i. The dietary assessments of the infants were collected using a mobile food record^TM. Foods consumed across four days were categorized into seven food groups. Indicators for food security were examined through an adapted infant food …

Moral Reconation Therapy: Efficacy And Predictors Of Dropout, Amber Maiwald

Antioch University Dissertations & Theses

No known research has been conducted on whether Moral Reconation Therapy (MRT) actually reduces criminogenic thinking. Similarly, no known research has been conducted to identify factors associated with dropout from the MRT program (i.e., choosing to leave the group before completion/release). Therefore, the purpose of this study was twofold: (a) to discover whether MRT reduces criminogenic thinking, and (b) to determine if criminogenic thinking, ACEs, cognitive abilities, and personality traits, particularly impulsivity, psychoticism, and antisocial traits, influence dropout. If significant effects in one or more of the aforementioned areas are discovered, individuals predicted to have the same profile as past …

Safety Evaluation Of Plasma-Treated Lettuce Broth Using In Vitro And In Vivo Toxicity Models, Caitlin Heslin, Daniela Boehm, Brendan F. Gilmore, Julianne Megaw, Paula Bourke

Articles

Cold atmospheric plasma is a promising new non-thermal technology for improving the microbiological safety and shelf-life of food products, particularly fresh produce and minimally processed fruit and vegetables. Limited research has been conducted on the safety of plasma-treated foods for human or animal consumption. This study focuses on basic safety studies by investigating lettuce broth treated with a di-electric barrier discharge plasma device as a fresh produce model in terms of in vitro cytotoxic and mutagenic effects on mammalian cells and its in vivo toxicity on Galleria mellonella larvae. Low cytotoxic effects were detected in vitro and mutagenic events were …

Ethics Committees For Clinical Experimentation At International Level With A Focus On Italy, Zakira Naureen, Tommaso Beccari, Robert S. Marks, Richard Brown, Lorenzo Lorusso, Derek Pheby, Stanislav Miertus, Karen L. Herbst, Liborio Stuppia, Gary T. Henehan, Benedetto Falsini, Ludovica Lumer, Munis Dundar, Matteo Bertelli, International Bioethical Study Group

Articles

Guiding legislation and associated bureaucracy for the ethical review of clinical trials observational studies and food related research play an important role in the competitiveness of a nation in the face of tough global competition to attract sponsors and investigators. This is of particular relevance in the case of multicentre trials and multidisciplinary research. Accordingly, in this report we tried to gather in-depth knowledge of the current role and practices of ethics committees nationwide in both clinical and research settings. This mini-review aims to describe the formulation and organization of ethical committees in Italy in order to provide a focus …

Dissipation Of Pesticide Residues On Grapes And Strawberries Using Plasma-Activated Water, Chaitanya Sarangapani, Laurence Scally, Miroslav Gulan, P. J. Cullen

Articles

In this study, we present a novel atmospheric air plasma discharge for the generation of plasma-activated water (PAW), with the aim of reducing pesticide residues on fresh fruit. For this purpose, a large discharge volume pin-to-plate cold plasma reactor was employed. The pesticide-spiked grapes and strawberries were processed with varying PAW concentrations to study their efficacies for pesticide degradation combined with an evaluation of any induced changes in key nutritional and quality attributes. The results suggest that the reduction of chlorpyrifos was 79% on grapes and 69% on strawberries while that of carbaryl was 86% on grapes and 73% on …

Sexual Behavior, Contraceptive Use, And Unmet Needs Among Unmarried Teenage Women In Uganda, Lawrence Were

Walden Dissertations and Doctoral Studies

At 25%, teenage pregnancy in Uganda is one of the highest in the world, and this has been mainly attributed to low contraceptive use and a high unmet need for modern contraceptives. Unmarried women aged 15 to 19 years in Uganda face unique cultural, ethical, financial, and legal barriers to the use of contraception. The purpose of this study was to investigate how sexual behavior, contraceptive use, and unmet needs among unmarried teenage women in Uganda aged 15 to 19 years are influenced by personal and environmental factors. Bandura’s social cognitive theory was used as a theoretical framework for this …