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Iron Homeostasis Is Altered In Response To Hypoxia And Hypothermic Preconditioning Inbrain Glial Cells, Lati̇fe Arzu Aral, Mehmet Ali̇ Ergün, Ayşe Başak Engi̇n, Alp Özgün Börcek, Hayrunni̇sa Bolay Belen

Turkish Journal of Medical Sciences

Background/aim: Altered iron metabolism is one of the pathophysiological mechanisms occurring during hypoxic injuries in the central nervous system. Proper homeostasis of cellular iron is regulated by iron import, storage, and export proteins that prevent excess iron overload or iron starvation in cells. Therapeutic hypothermia is an approved treatment for hypoxic ischemia in newborns, but the underlying molecular mechanism is still unknown. We studied the effects of hypoxia, preceded with preconditioning, on the iron homeostasis of glial cells, known as a major actor in the inflammatory process during perinatal brain injury. Materials and methods: Primary microglia and astrocytes in culture …

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

Global Threat Of Covid 19 And Evacuation Of The Citizens Of Different Countries, İrfan Şencan, Semanur Kuzi̇

Turkish Journal of Medical Sciences

Beginning from China on December 2019, COVID-19 epidemic has spreaded all over the world in a short period of time and has been a pandemic. In challenge with this pandemic quarantine technique has been used widely after tens of years. In the course of the pandemic, many countries evacuated their citizens from affected regions and combined the evacuation with quarantine process. Some examples of these countries who evacuated their citizens are Germany, Italy, Spain, and USA. In further times, during the course of pandemic, according to spread, other countries evacuated their citizens from these countries too. Despite being the origin …

Covid-19 Outbreak Control, Example Of Ministry Of Health Of Turkey, Yasemi̇n Demi̇rbi̇lek, Gülen Pehli̇vantürk, Zeynep Özge Özgüler, Emi̇ne Alp Meşe

Turkish Journal of Medical Sciences

Our first COVID-19 case in Turkey was a 44-year-old male who referred to the hospital on March 9, 2020. The first related death occurred on March 17, 2020. Preparedness for the pandemic has been ongoing before the first case was detected. The National Pandemic Plan was published in 2006. The Pandemic Influenza National Preparedness Plan was available after being updated in light of experiences gained during the 2009 Influenza A pandemic. Accordingly, Pandemic Coordination Boards and Operation Centers have been established on the national and provincial levels. This was an adaptable plan to the Novel Coronavirus Disease (COVID-19). We formed …

Critically Ill Covid-19 Patient, Burçi̇n Halaçli, Akin Kaya, Arzu Topeli̇ İski̇t

Turkish Journal of Medical Sciences

Coronavirus disease 2019 (COVID-19) stands out as the major pandemic that we have experienced in the last century. As it affects every social structure, it brought the importance of intensive care support once again to the agenda of healthcare system after causing severe acute respiratory syndrome. The precautions to be taken against this virus, where our knowledge is extremely small, intensive care units take an indispensable place in pandemic planning. In this review, we aimed to emphasize the crucial points regarding intensive care management of COVID-19 patients, which we have written not only for intensivists but also for all healthcare …

Sars-Cov-2 Epidemiology And Control, Different Scenarios For Turkey, Eskild Petersen, Ayşe Deni̇z Gökengi̇n

Turkish Journal of Medical Sciences

Background/aim: Coronavirus Infectious Disease 2019 (COVID-19) is now a pandemic spreading in most countries including Turkey. Materials and methods: The current knowledge of COVID-19 and the virus causing it, SARS-CoV-2, was reviewed. The epidemiology and control in different countries was compared and the differences discussed. Results: The population attack rates and case fatality rates vary from country to country with Lombardy in northern Italy reporting an attack rate in the general population of 0.37% compared to 0.004% in Hong Kong. The differences are caused by different testing strategies and reporting systems. Conclusion: Turkey is early in the outbreak. Different control …

The Early Impact Of The Covid-19 Pandemic On The Global And Turkish Economy, Ömer Açikgöz, Asli Günay

Turkish Journal of Medical Sciences

Background/aim: Individuals infected by the Covid-19 potentially are at risk of health and economic well-being. Today, the Covid-19 is a global issue, and the world economy can be interpreted as almost at the standstill. In this context, this study aims to discuss the potential first reactions of short and long term global economic impacts of the pandemic through sectors by assessing its costs according to the data announced for both the world and Turkey. In addition, this study tries to put forth possible economic and political scenarios for the post-pandemic world. Materials and methods: This is a review article that …

The Prevalence Of Clostridium Perfringens In Retail Meat Of Mardan, Pakistan, Mumtaz Ali Khan, Sher Bahadar Khan, Imdad Ullah Khan, Asad Sultan, Rajwali Khan, Muhammad Shahid, Amjad Islam Aqib, Shakirullah Khan, Alam Zeb Khan, Mubbashar Hassan

Turkish Journal of Veterinary & Animal Sciences

The most prevailing bacteria in distribution is Clostridium perfringens (C. perfringens) which is ranked 1st among fatal diseases in small ruminants. This rapidly growing food borne pathogen is present in water, food, soil, air, and humans and animals intestinal tract. In the present study, a cross-sectional study was performed to sort out the prevalence of C. perfringens types estimation in various retail meats and areas of Mardan district, Pakistan. 600 fresh meat samples (equally from cows, sheep and goats) were collected from retail shops. C. perfringens was diagnosed in various types of meat however highest prevalence was found in goats …

In Vitro Investigation Of Netosis Reaction Developing From Dog Polymorphonuclearneutrophils To Toxoplasma Gondii, Güneş Karakurt, Kader Yildiz

Turkish Journal of Veterinary & Animal Sciences

Toxoplasma gondii is known to develop extracellular traps from neutrophils in some animal species such as mice, cattle, sheep, cats, and donkeys. This study aimed to investigate the extracellular trap structures formed in dog polymorphonuclear leukocytes (PMNs) to T. gondii tachyzoites in vitro. Dog PMN was isolated using Percoll dilutions (45%, 54%, 63%, and 72%). After incubation with tachyzoites, the extracellular traps originating from the dog PMNs were observed in the extracellular areas. Histones (H3), myeloperoxidase (MPO), and neutrophil elastase (NE), the characteristic features of NETosis reaction, were detected in extracellular areas. The tachyzoites were observed between the extracellular trap …

An Atypical Localization Of Bacillus Anthracis In A Cow's Milk And Udder, Mi̇tat Şahi̇n, Fati̇h Büyük, Özgür Çelebi̇, Mustafa Reha Coşkun

Turkish Journal of Veterinary & Animal Sciences

A 6-year-old Simental-Swiss Brown cross-bred cow, which aborted in the first trimester of the gestation and involuntarily presented anthrax bacilli around the udder, was subjected to this study. The cow was vaccinated with an attenuated anthrax vaccine (Bacillus anthracis 34 F2) 6 months ago and had normal physical examination findings. Samples taken 10 days after the abortion were representative of all possible spaces that could carry the bacteria such as milk, blood, environment, and swabs from rectum, udder and tits of an infected cow. Microbiological examination was carried out by staining the smears with Azure and in vitro culture of …

Addition Of Intratympanic Steroid Or Hyperbaric Oxygen Treatment To Systemic Steroid Treatment In Sudden Idiopathic Sensorineural Hearing Loss Treatment, And Long-Term Results Of Salvage Treatment, Kemal Keseroğlu, Gökhan Toptaş, Ahmet Uluat, Ömer Bayir, Emel Çadalli Tatar, Güleser Saylam, Mehmet Hakan Korkmaz, Ali̇ Özdek

Turkish Journal of Medical Sciences

Background/aim: This study aims to determine the therapeutic superiority of the addition of intratympanic steroid or hyperbaric oxygen therapy to systemic steroid treatment in idiopathic sudden sensorineural hearing loss as initial treatment, and evaluate the long-term results of salvage treatment. Materials and methods: This study was a retrospective clinical trial with a total of 96 patients with idiopathic sudden sensorineural hearing loss. Patients were divided into 3 groups. Group 1 (n: 32) received systemic steroid treatment. Group 2 (n: 32) received the Group 1 protocol plus intratympanic steroid treatment. Group 3 (n: 32) received the Group 1 protocol plus hyperbaric …

Impact Of The Demographic And Aetiological Factors And Intraoperative Findings On Postoperative Outcomes In Chronic Otitis Media Surgery, Süleyman Cebeci̇, Mehmet Suat Özbi̇len, İsmet Bayramoğlu, Yusuf Kemal Kemaloğlu, Kadi̇r Kemal Uygur, Yildirim Ahmet Bayazit, Recep Karamert

Turkish Journal of Medical Sciences

Background/aim: Surgical success is related with many factors belonging to both the patient and the disease. This study aims to analyse the preoperative and intraoperative characteristics, the postoperative results, and the factors affecting the surgical success in different types of chronic otitis media (COM).Materials and methods: A total of 1510 ears of 1398 patients who underwent COM surgery were included in the study. Postoperative results were obtained from 376 ears of 356 patients who had been followed after surgery. The demographic characteristics of the patients, such as age and sex, operative findings, preoperative audiological examination results, and final audiometric and …

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

Adiponectin Levels Decrease Independently Of Body Mass Index And Diabetes Type Afterthe Normalization Of Hyperglycemia, Nalan Meti̇n Aksu, Duygu Yazgan Aksoy, Meltem Akkaş, Neşe Çinar, Fatma Uçar, Okan Bülent Yildiz, Aydan Usman

Turkish Journal of Medical Sciences

Background/aim: Acute hyperglycemia is generally a frequently encountered condition in the emergency department (ED), because it is seen as a complication of diabetes mellitus (DM). In this study, we aimed to detect the change in adiponectin levels during acute hyperglycemic states and after normalization of blood glucose with insulin treatment. Materials and methods: Forty-eight patients over the age of 18 years who were admitted to the ED with acute hyperglycemia were included in the study. Serum samples were taken from patients on admission and 6 h after the normalization of blood glucose with insulin treatment, and adiponectin levels were measured …

Different Perspectives Of Immunizations During Pregnancy, Gökce Celep, Aysu Duyan Çamurdan, Fatma Nur Baran Aksakal, Osman Fadil Kara

Turkish Journal of Medical Sciences

Background/aim: Pregnant women and infants are at risk of severe lower respiratory tract infections induced by influenza or pertussis. The uptake of both vaccines is poor in spite of proven benefits and safety. We aimed to determine the knowledge and attitude of pregnant women and their primary healthcare providers towards immunization during pregnancy. Materials and methods: This cross-sectional and interventional study was conducted in northern Turkey in 2016. It had 3 different groups including 786 pregnant women, 146 primary healthcare staff, and 97 family practitioners. Different questionnaires were filled by each group. The intervention phase of the study consisted of …

The Determination Of Antimicrobial And Antibiofilm Activities Of Foodborne Lactic Acid Bacteria Against Enterobacter Cloacae Isolates, Beytullah Kenar, Mi̇ne Eri̇k, Sevi̇m Feyza Erdoğmuş, Safi̇ye Eli̇f Korcan, Zahi̇de Köse, Gül Durmaz

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to investigate the antimicrobial and antibiofilm activities of 10 different lactic acid bacteria (LAB) strains isolated from local food sources of animal origin against 4 Enterobacter cloacae isolates obtained from clinical cases and determine their adhesion potentials to intestinal epithelial cells. In this study, all Enterobacter cloacae isolates (P3, P4, P5, P7) identified with the BD Phoenix automation system were detected to form biofilm with both Congo red agar and Microtiter plate methods. Amoxicillinclavulanate, cefuroxime, and ampicillin resistance was determined in all isolates. It was determined that LAB strains producing exopolysaccharide (EPS) were able …

Effect Of Sesamin On Protection Of Equine Articular Cartilage Degradation In Vitro, Siriporn Peansukmanee, Siriwan Tangyuenyong, Siriwan Ongchai

Turkish Journal of Veterinary & Animal Sciences

Black sesame seed is a potential herbal medicine for osteoarthritis treatment as it contains sesamin, which has antiinflammatory properties and has demonstrated chondroprotective effects in many species. Horses are particularly susceptible to osteoarthritis. Inflammatory mediators and matrix metalloproteinase are important factors causing cartilage degradation. This study aimed to investigate the protective potential of sesamin (0.5-2.0 μM) against interleukin (IL)-1ß-induced equine cartilage explant degradation. The cartilage degradation was monitored by measuring the release of cartilage matrix molecules in culture media including sulfatedglycosaminoglycans and hyaluronan by calorimetric assay and ELISA assay, respectively. The remaining contents of collagen and uronic acid (UA) within …

Dmem And Fbs As Thawing Solutions For Frozen Semen Of Pigs Can Improve Sperm Motility And Sow Reproductive Performance, Peng Zheng, Ziming Wang, Xiaoyu Li, Fushuo Huang, Mingjun Ma, He Huang

Turkish Journal of Veterinary & Animal Sciences

The purpose of this experiment was to investigate the effects of Beltsville thawing solution (BTS), Androhep, and Dulbecco?s modified Eagle medium + Fatal bovine serum (D-F) as diluents of frozen semen on sperm motility and sow reproductive performance. In experiment 1, boar semen was collected and diluted to 2.0 × 109/60 mL, 1.5 × 109/60 mL, and 1.5 × 109/40 mL with Androhep. The appropriate semen dose was determined by postcervical insemination. In experiment 2, boar semen was fumigated with liquid nitrogen and thawed semen was diluted to 1.5 × 109/40 mL with D-F, Androhep, and BTS, respectively. The effects …

The Potential Of Salvia Officinalis As A Suppressor Of Cell Proliferation In Animal Feed And Human Nutrition: An Experimental Stud, Muhammet Kuddusi̇ Erhan

Turkish Journal of Veterinary & Animal Sciences

The objective of this study was to examine the in vitro cytotoxic activities of Salvia officinalis (sage) oil on human immortalized keratinocyte (HaCaT) cell lines by using an [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide] (MTT) cytotoxicity assay after the Salvia officinalis oil administration in different doses and time-points. In vitro cytotoxic activities of Salvia officinalis oil on HaCaT cell lines were assessed, and MTT assays were used to determine cell viability. The HaCaT cells (100 µL) were cultured in 96well plates at 2 × 104 cells per well and treated with different concentrations of Salvia officinalis oil (25 µM, 50 µM, 100 µM, 150 µM, …

Effect Of Supplementing Additives In Leptin-Enriched Maturation Medium During In Vitro Maturation And Vitrification Of Goat Oocytes, Reema Talukdar, Ranjan Kumar Biswas, Govindasamy Kadirvel, Bharat Chandra Deka, Sudip Sinha, Lukumoni Buragohain, Birina Bora

Turkish Journal of Veterinary & Animal Sciences

The present study aimed to evaluate the effect of supplementing epidermal growth factor (EGF), insulin-like growth factor-I (IGF-I), fetal bovine serum (FBS), and bovine serum albumin (BSA) in different combinations in a maturation medium (MM) comprising TCM-199 + 5 µg/mL 17-ß estradiol + 5 µg/mL ovine-luteinizing hormone (oLH) + 5 µg/mL pure follicle-stimulating hormone (pFSH) + 100 µM/mL cysteamine containing the best concentration of leptin among 10/20/25/30 ng/mL on in vitro maturation (IVM) and subsequent vitrification of matured goat oocytes. The IVM of oocytes was carried out in a CO2 incubator for 27 h at 38.5 °C. The percentage of …

Effects Of Selenium And Zinc Supplementation On Cadmium Toxicity In Broilers, Evangelos Zoidis, Athanasios C. Pappas, Ali Al-Waeli, Constantinos A. Georgiou, George P. Danezis, Nikos Demiris, George Zervas, Konstantinos Fegeros

Turkish Journal of Veterinary & Animal Sciences

Cadmium (Cd) is a toxic metal regarded as an environmental pollutant. The potential ameliorative effect of simultaneous addition of Se and Zn to broilers against Cd toxicity was examined. A total of 180 as-hatched broilers were used. There were 4 replicate pens of 3 dietary treatments: T1, T2, and T3. In T1, Se, Cd, and Zn were added to a basal diet at 0.3, 0, and 100 ppm, in T2 at 0.3, 50, and 150 ppm, and in T3 at 0.5, 50, and 150 ppm respectively. Selenium, Cd, Ca, Co, Cu, Fe, Li, Mg, Mn, Sb, As, Cr, Pb, Mo, …

Arsenic, Cadmium, Mercury, And Lead In Date Mussels From The Sarajevo Fish Market (Bosnia And Herzegovina): A Preliminary Study On The Health Risks, Elma Omeragic, Aleksandra Marjanovic, Jasmina Djedjibegovic, Amila Turalic, Amir Causevic, Haris Niksic, Faruk Caklovica, Miroslav Sober

Turkish Journal of Veterinary & Animal Sciences

The main objective of this study was to determine the content of heavy metals (Cd, Pb, Hg) and metalloid (As) in samples of date mussels (Lithophaga lithophaga L., 1758) in order to evaluate the health risks for mussel consumers. Samples of shellfish were obtained from commercial sources and fishery in the area of Sarajevo. The content of heavy metals and arsenic is determined in a total of 46 samples. Samples were prepared by microwave digestion. For the analysis of total As, cadmium and lead, an atomic absorption spectrophotometer with graphite furnace was used, while mercury content was determined using a …

Influence Of Social Rank On Certain Stress Response Variables And Behavioralcharacteristics Of Adult Rams, Eli̇f Ergül Eki̇z, Hülya Yalçintan, Alper Yilmaz, İbrahi̇m Akyazi, Evren Eraslan, Bülent Eki̇z

Turkish Journal of Veterinary & Animal Sciences

Dominance rank within a group can affect the stress level of an animal. However, there is no consensus on whether the dominant or subordinate animals are physiologically more stressed. It was aimed herein to determine the effect of social rank on the stress level and expression of some behaviors of adult Hemsin, Chios, and Karakul rams. According to their dominance index (DI) values, the rams were classified as low-ranked (DI < 0.33; n = 13), medium-ranked (DI: 0.33-0.66; n = 13), and high-ranked (DI > 0.66; n = 13) individuals. The low-ranked rams had lower body weight, body length, chest depth, chest circumference, cannon bone circumference, and tail width than the medium- and high-ranked rams. …

Cd Markers Of Camel (Camelus Dromedarius) Intestine Naturally Infected Withmycobacterium Avium Subsp. Paratuberculosis: Distinct Expression Of Madcam-1 Andcx3cr1, Saeed Al-Ramadan, Kazem Al-Mohammed Salem, Ibrahim Alshubaith, Ahmed Alluwaimi

Turkish Journal of Veterinary & Animal Sciences

Mycobacterium avium subsp. paratuberculosis (MAP) infection in camel requires extensive research, particularly the immune responses in the intestine. This study aimed to investigate the nature of the cellular populations that are driven by the immunopathological responses in the camel intestine infected with MAP at different ages. Immunohistochemical staining was carried out on tissues obtained from naturally infected young (5-10 years old) and older (12-15 years old) camels. The staining of the tissues, ileum, mesenteric lymph node, jejunum, and supramammary lymph nodes, with anti-CD3$^{+}$, CD4$^{+}$, CD8$^{+}$, CD25$^{+}$, CD11c$^{+}$, CD14$^{+}$, WC1$^{+}$, CX3CR1, and Madcam-1 monoclonal antibodies revealed high expression of the molecules …

Antibiotic Susceptibility And Phylogenetic Analyses For The Origins And Serotypes Of Listeria Monocytogenes Strains Isolated From Ice Cream And Cream Cakes, Orkun Babacan

Turkish Journal of Veterinary & Animal Sciences

Listeria monocytogenes is a zoonotic bacterium which also infects humans. The aim of this study was to isolate this organism from cream cakes and ice cream and obtain 16S rRNA and hlyA gene sequences from isolates in order to perform phylogenetic analyses. Serotypes and antibiotic susceptibility were also determined. The cream cake and ice cream samples were examined for L. monocytogenes according to ISO 11290-1 and using the mini Vidas LMO 2 kit procedure. Antibiotic susceptibilities were investigated using the disc diffusion method according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and the Clinical and Laboratory Standards Institute …

Effect Of Chemical- And Toxin Binder-Treated Cotton Seed Cake On Milk Production, Milkcomposition, And Aflatoxin Concentration In Milk Of Nili Ravi Lactating Buffaloes, Murtaza Ali Tipu, Anjum Khalique, Muhammad Naveed Ul-Haque, Muhammad Qamer Shahid, Maqsood Akhtar, Mubashir Ilyas

Turkish Journal of Veterinary & Animal Sciences

Twelve multiparous Nili Ravi buffaloes were assigned to 1 of 3 treatments in a randomized, replicated 3 × 3 Latin square design to evaluate the effect of chemical (calcium propionate)- and toxin binder (sodium bentonite)-treated cotton seed cake (CSC) on milk yield and transfer of milk toxin (M1). Periods (20 days) were allocated for each treatment. In the 1st treatment (control), CSC with 100 μg/kg of aflatoxin B1 (AFB1) was fed to buffaloes. The 2nd and 3rd treatments were 0.5% calcium-propionate-treated CSC and 1.0% sodium-bentonite-treated CSC, respectively. Each group had 4 multiparous buffaloes. The buffaloes given 0.5% calcium propionate CSC …

Comparative Evaluation Of The Effects Of Different Thawing Methods On Bull Spermcharacteristics With Computer-Assisted Semen Analysis, Murat Selçuk, Eser Akal, Burcu Esi̇n, Mustafa Yi̇ği̇t Ni̇zam, Merve Deni̇z Genç

Turkish Journal of Veterinary & Animal Sciences

Postthaw survival of spermatozoa with high motility and vitality is required for successful artificial insemination. The aim of this study was to compare the effects of two different thawing methods on motility, morphology, kinematic parameters, and viability of spermatozoa with a computer-assisted semen analyzer (CASA). Frozen bull spermatozoa were thawed by using two different thawing procedures: 1) Water bath; straws were thawed in a water bath at 37 °C for 30 s. 2) Dry thawing system; straws were thawed in a dry thawing device at 37 °C for 30 s. A total of 10 straws were used for each thawing …

“Maths Outside Of Maths”: Pre-Service Teachers’ Awareness Of Mathematical And Statistical Thinking Across Teachers’ Professional Work, Judy Bailey, Bronwen Cowie, Beverley Cooper

Australian Journal of Teacher Education

Mathematical and statistical thinking is involved across the breadth of people’s home and work life and leisure activities. This paper reports on an aspect of a project that aimed to develop pre-service teacher awareness of the mathematical and statistical thinking required across the breadth of primary teachers’ professional role. This thinking is conceptualised as the mathematics and statistics embedded in each of the curriculum learning areas, in data literacy, and administration and management tasks. Mentor meetings indicated pre-service teachers who were completing a one-year graduate diploma initially had a limited awareness of the extent of this thinking. Through focus group …

Influence Of Teachers’ Metacognitive Skills On Development Of Early-Childhood Students, Sunthorn Thienngam, Aree Promlek, Koranit Thongsaard

Australian Journal of Teacher Education

The objectives were to study and develop metacognitive skills of 1,616 early childhood in-service teachers in Child Development Center, Thailand. The quasi-experimental design were implied. Research Tools were Metacognitive Self-Assessment Questionnaire and scoring rubrics for early childhood students’ assessment. Data were analyzed through fundamental statistics and inferential statistics. The research results were as follows:

The teachers who joined with the program had got higher metacognitive skills score for both knowledge of cognition and knowledge of regulation than the other one. The teachers who had different supportive factors, different attitude towards pedagogy and different self-efficacy, would have got statistically significant difference …

A Whole-School Approach To Promoting Staff Wellbeing, Leanne Lester, Carmel Cefai, Valeria Cavioni, Amy Barnes, Donna Cross Professor

Australian Journal of Teacher Education

A caring school community can enhance whole-school wellbeing including the wellbeing of school staff, which directly impacts on student academic, social and emotional wellbeing. This study firstly examines the validity and reliability of a proposed whole-school staff wellbeing evaluation tool which uses a set of whole-school wellbeing indicators to identify strengths and areas for improvement within the school environment which may be impacting on staff wellbeing. Secondly, the association between factors found within the whole-school staff wellbeing tool with staff self-reported mental health are examined, and finally, the influence of person characteristics and role of factors on perceived whole-school staff …