Exosomes As Systemic Mediators Of Nanotube Induced Neurotoxicity, Christopher G. Canal

Theses and Dissertations

Extra-pulmonary effects of nanoparticle inhalation have been well documented; however, mechanisms for conveying peripheral bioactivity remain elusive. Recent studies point to indirect molecular mediators shed into the circulation. Protein and lipid alternatives to cytokines or chemokines have been proposed, yet the diversity among responses suggests a broader assemblage of factors. Recently we have proposed proteolytic fragment peptides as an additional source of bioactivity, which interestingly were significantly associated with exosomal proteins after enrichment analysis. Here we tested whether modeled exposure to multi-walled carbon nanotubes (MWCNT) could alter the composition and bioactivity of circulating exosomes. Male C57BL/6 mice were exposed by …

Western Representation On Twitter In Relation To Orientalism And Framing: A Content Analysis Of #Saudi Arabia And #Saudis, Wedyan A. Kattan

Theses and Dissertations

Based on framing theory, Said’s Orientalism, and Hall’s theory of representation, this dissertation explores how the kingdom of Saudi Arabia is represented on the social media platform Twitter. Specifically, the study aims to identify how Saudi Arabia and Saudis are represented in English-language tweets by Western media in the years after several political incidents in the region, such as the Yemen war, and new political leadership in Saudi Arabia that has introduced many economic and social reforms. Thus, the overarching research question in this study is, how have Saudi Arabia and Saudis been presented on Twitter recently? This study sheds …

Ca2+/Calmodulin-Dependent Protein Kinase Type Ii (Camkii) Regulates Histone Methylation To Promote Zebrafish Hematopoietic Stem Cell Specification, Sanyam Patel

Theses and Dissertations

Ca²⁺/calmodulin dependent protein kinase II (CaMKII) is an important signaling molecule involved in many developmental processes. This project aims to understand the role of CaMKII in specification of hematopoietic stem cells (HSCs) in zebrafish. HSCs undergo hematopoiesis to specify all cells that constitute blood. The process of hematopoiesis along with the specification of hematopoietic stem cells is conserved in vertebrates. CaMKII is expressed in tissues important for HSC specification, including the somites, notochord, and dorsal aorta. The dorsal aorta is the site of HSC specification in zebrafish. Injection of camk2g1 translational blocking antisense oligonucleotides (MO) or Cas9 guide …

Development Of A Screening Assay For Type Iii Secretion System Inhibitors And High Throughput Screening Campaign Of Inhibitors Of Prp Of Staphylococcus Aureus, Heather A. Pendergrass

Theses and Dissertations

Antibiotics inhibit the growth or survival of bacteria by targeting their essential functions.¹ Due to weaknesses in traditional antibiotics and the increasing prevalence of antibiotic resistance genes, virulence factors are being targeted for therapeutic treatment of bacterial infection.² We have developed an assay to quantify and observe type III secretion system (T3SS) activity. The type III secretion system (T3SS) is a virulence factor present in some Gram-negative pathogens including enteropathogenic and enterohemorrhagic E. coli (EPEC and EHEC, respectively),³ and others.^4–9 The T3SS between EPEC and EHEC are highly conserved and share over 90% sequence identity with …

A Longitudinal Test Of Mexican Teen Mothers’ Cultural Characteristics And Children’S Language Skills Via Mothers’ Language, Arlenis A. Santana

Theses and Dissertations

The current study includes 204 Mexican teen mothers and their children from a larger study who were interviewed when children were 3 years old (Wave 4; W4), 4 years old (W5), and 5 years old (W6). The current study is guided by the integrative model of developmental competencies (García Coll et al., 1996), which suggests that parents’ adaptive cultural characteristics and exchanges with their children inform children’s developmental competencies. Thus, the current study examined whether teen mothers’ adaptive cultural characteristics (i.e., familism values, language competency pressures, and involvement in Mexican culture and U.S. mainstream culture) at W4 informed mothers’ Spanish …

(In)Equities In The Publishing Industry: The Politics Of Representation, Hallie R. Lepphaille

Cal Poly Humboldt theses and projects

This project contains an overview and key introductory sections of an intersectional, equity-based literary publishing course textbook. The full-length edited collection, currently under external review for publication, seeks to rectify long-held disparities of the publishing industry in regard to hiring, acquisitions, developmental editing, and considerations in audience, readerships, and marketing. Each chapter examines the ways that racism, ableism, heterosexism, and cisnormativity, operate in the industry, limiting who is represented at an editor’s desk and in the pages of published books. The collection is intended to be utilized in upper-division and graduate-level literary publishing courses. This project is a response to …

Aspen Growth Response In The Presence Of Inter-Annual Climate Fluctuation And Disturbance In The Lake Tahoe Basin, Keath K. Sakihara

Cal Poly Humboldt theses and projects

In the western US, aspen forests tend to be small and rare, but have great ecological importance. There is much interest and concern over how aspen in the Sierra Nevada Mountains of the western USA will respond to a changing climate and future disturbances. Impacts from climate change create stress on aspen trees that further compound threats to aspen communities. This analysis assessed the radial growth response of aspen under previously recorded climate conditions to better understand how measurable climate variables affect aspen growth. Along with aspen’s growth response to climate, this analysis also assessed the growth response of aspen …

Corporate Purpose In A Populist Era, Stephen M. Bainbridge

Nebraska Law Review

In the wake of the 2016 U.S. presidential election and similar developments in parts of Europe, commentators widely acknowledged the rise of populist movements on both the right and left of the political spectrum that were deeply suspicious of big business. This development potentially has important implications for the law and practice of corporate purpose.

Left-of-center corporate social responsibility campaigners have long advocated the use of “boycotts, shareholder activism, negative publicity, and so on” to pressure corporate managers to act in ways those campaigners deem socially responsible. Right-of-center populists could use the same tactics to induce corporate directors to make …

Vaccine Hesitancy: Experimentalism As Regulatory Opportunity, Ana Santos Rutschman, Timothy L. Wiemken

All Faculty Scholarship

This symposium on patient innovation has prompted us to explore problems related to departures from official vaccination schedules. At a time in which vaccine confidence has been plummeting across the world, we argue that a more granular understanding—and ultimately a more finely tuned regulatory framework—is needed to reflect the current behavioral heterogeneity among indicated patients who choose to forego or delay administration of recommended vaccines. In particular, we focus on a phenomenon we term “vaccine staggering:” a departure from vaccination schedules in the form of delays in receiving one or more vaccines, which is motivated by the desire to boost …

2019-20 Annual Report, Tennessee. Board Of Paroles

Annual Reports

This document is the annual report for the Tennessee Board of Parole during the fiscal year.

Immunomagnetic Separation And Listeria Monocytogenes Detection With Surface- Enhanced Raman Scattering, Hande Yeğenoğlu Akçinar, Belma Aslim, Hi̇lal Torul, Burcu Güven, Adem Zengi̇n, Zeki̇ye Suludere, İsmai̇l Hakki Boyaci, Uğur Tamer

Turkish Journal of Medical Sciences

Background/aim: We aimed to develop a rapid method to enumerate Listeria monocytogenes (L. monocytogenes) utilizing magnetic nanoparticle based preconcentration and surface-enhanced Raman spectroscopy measurements. Materials and methods: Biological activities of magnetic Au-nanoparticles have been observed to have the high biocompatibility, and a sample immunosensor model has been designed to use avidin attached Au-nanoparticles for L. monocytogenes detection. Staphylococcus aureus (S. aureus) and Salmonella typhimurium (S. typhimurium) bacteria cultures were chosen for control studies. Antimicrobial activity studies have been done to identify bio-compatibility and bio-characterization of the Au-nanoparticles in our previous study and capturing efficiencies to bacterial surfaces have been also …

An Atypical Localization Of Bacillus Anthracis In A Cow's Milk And Udder, Mi̇tat Şahi̇n, Fati̇h Büyük, Özgür Çelebi̇, Mustafa Reha Coşkun

Turkish Journal of Veterinary & Animal Sciences

A 6-year-old Simental-Swiss Brown cross-bred cow, which aborted in the first trimester of the gestation and involuntarily presented anthrax bacilli around the udder, was subjected to this study. The cow was vaccinated with an attenuated anthrax vaccine (Bacillus anthracis 34 F2) 6 months ago and had normal physical examination findings. Samples taken 10 days after the abortion were representative of all possible spaces that could carry the bacteria such as milk, blood, environment, and swabs from rectum, udder and tits of an infected cow. Microbiological examination was carried out by staining the smears with Azure and in vitro culture of …

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

Arsenic, Cadmium, Mercury, And Lead In Date Mussels From The Sarajevo Fish Market (Bosnia And Herzegovina): A Preliminary Study On The Health Risks, Elma Omeragic, Aleksandra Marjanovic, Jasmina Djedjibegovic, Amila Turalic, Amir Causevic, Haris Niksic, Faruk Caklovica, Miroslav Sober

Turkish Journal of Veterinary & Animal Sciences

The main objective of this study was to determine the content of heavy metals (Cd, Pb, Hg) and metalloid (As) in samples of date mussels (Lithophaga lithophaga L., 1758) in order to evaluate the health risks for mussel consumers. Samples of shellfish were obtained from commercial sources and fishery in the area of Sarajevo. The content of heavy metals and arsenic is determined in a total of 46 samples. Samples were prepared by microwave digestion. For the analysis of total As, cadmium and lead, an atomic absorption spectrophotometer with graphite furnace was used, while mercury content was determined using a …

Comparative Evaluation Of The Effects Of Different Thawing Methods On Bull Spermcharacteristics With Computer-Assisted Semen Analysis, Murat Selçuk, Eser Akal, Burcu Esi̇n, Mustafa Yi̇ği̇t Ni̇zam, Merve Deni̇z Genç

Turkish Journal of Veterinary & Animal Sciences

Postthaw survival of spermatozoa with high motility and vitality is required for successful artificial insemination. The aim of this study was to compare the effects of two different thawing methods on motility, morphology, kinematic parameters, and viability of spermatozoa with a computer-assisted semen analyzer (CASA). Frozen bull spermatozoa were thawed by using two different thawing procedures: 1) Water bath; straws were thawed in a water bath at 37 °C for 30 s. 2) Dry thawing system; straws were thawed in a dry thawing device at 37 °C for 30 s. A total of 10 straws were used for each thawing …

“Maths Outside Of Maths”: Pre-Service Teachers’ Awareness Of Mathematical And Statistical Thinking Across Teachers’ Professional Work, Judy Bailey, Bronwen Cowie, Beverley Cooper

Australian Journal of Teacher Education

Mathematical and statistical thinking is involved across the breadth of people’s home and work life and leisure activities. This paper reports on an aspect of a project that aimed to develop pre-service teacher awareness of the mathematical and statistical thinking required across the breadth of primary teachers’ professional role. This thinking is conceptualised as the mathematics and statistics embedded in each of the curriculum learning areas, in data literacy, and administration and management tasks. Mentor meetings indicated pre-service teachers who were completing a one-year graduate diploma initially had a limited awareness of the extent of this thinking. Through focus group …

Influence Of Teachers’ Metacognitive Skills On Development Of Early-Childhood Students, Sunthorn Thienngam, Aree Promlek, Koranit Thongsaard

Australian Journal of Teacher Education

The objectives were to study and develop metacognitive skills of 1,616 early childhood in-service teachers in Child Development Center, Thailand. The quasi-experimental design were implied. Research Tools were Metacognitive Self-Assessment Questionnaire and scoring rubrics for early childhood students’ assessment. Data were analyzed through fundamental statistics and inferential statistics. The research results were as follows:

The teachers who joined with the program had got higher metacognitive skills score for both knowledge of cognition and knowledge of regulation than the other one. The teachers who had different supportive factors, different attitude towards pedagogy and different self-efficacy, would have got statistically significant difference …

A Whole-School Approach To Promoting Staff Wellbeing, Leanne Lester, Carmel Cefai, Valeria Cavioni, Amy Barnes, Donna Cross Professor

Australian Journal of Teacher Education

A caring school community can enhance whole-school wellbeing including the wellbeing of school staff, which directly impacts on student academic, social and emotional wellbeing. This study firstly examines the validity and reliability of a proposed whole-school staff wellbeing evaluation tool which uses a set of whole-school wellbeing indicators to identify strengths and areas for improvement within the school environment which may be impacting on staff wellbeing. Secondly, the association between factors found within the whole-school staff wellbeing tool with staff self-reported mental health are examined, and finally, the influence of person characteristics and role of factors on perceived whole-school staff …

Fun And Friendly Or Wild And Offensive? Preservice Teachers’ Use Of And Image Conveyed By Social Media, Marlynn M. Griffin, Cordelia Zinskie

Australian Journal of Teacher Education

The study presents survey results from 515 preservice teachers at a regional United States institution on their social media use, specifically, their self-reported personal image conveyed on their social media sites, likelihood of posting problematic content on their social media sites, and preference for various others viewing their social media sites. While many preservice teachers reported appropriate social media use, some participants conveyed inappropriate personal images; had reservations about supervisors, employers, and university faculty viewing their sites; and were likely to post problematic content. Thus, it is incumbent for teacher preparation programs to develop clear policies as preservice teachers must …

Elaborating A Model For Teacher Professional Learning To Sustain Improvement In Teaching Practice, Pauline W. Thompson, Jeana A. Kriewaldt, Christine Redman

Australian Journal of Teacher Education

: Effective professional learning is acknowledged as a key lever to improve teacher practice. However, many studies report significant variation in the effectiveness of the types of programs on offer. Recently, there has been a move from the traditional single-event, passive approach to more collaborative and ongoing forms of professional learning. Interestingly, researchers have paid little attention to understanding the experience of professional learning from the teachers’ viewpoint. This research sought to develop this understanding by following the attitudes and behaviours of a group of secondary teachers as they participated in an ongoing professional learning program. This professional learning program …

Examination Of Text And Video-Formatted Learning Diaries In The Teacher Education, Murat Debbag, Mustafa Fidan

Australian Journal of Teacher Education

This study aims to comparatively examine the text and video formatted learning diaries created within the scope of a school experience course which is a part of teacher education programs for prospective science teachers (PSTs). The case study design was used in this study. The participants created their learning diaries both in text and video formats for the school experience. Results showed that both text formatted diaries and video formatted diaries not only made it possible for the PSTs to see, review, and correct their deficiencies with respect to the profession of teaching, but also made contributions to the development …

Asian Students' Perceptions Of How They Are Seen In 'The West': A Case Study At An Australian University, Toni J. Dobinson

Australian Journal of Teacher Education

Australian universities attract increasing numbers of students from the Asia-Pacific region. It is important, therefore, that academics have meaningful understandings of these students in order to provide them with a supportive learning environment. This article suggests that part of this understanding is being aware of the ways in which some of these students perceive they are seen by those in the receiving countries and the discourses which may feed these perceptions. The qualitative study reported here outlines the perceptions of 10 Vietnamese offshore postgraduates (VOPs) and nine Asian onshore postgraduates (AOPs) from different Asian countries at an Australian university. All …

Teacher Wellbeing In Remote Australian Communities, Alison S. Willis, Peter R. Grainger

Australian Journal of Teacher Education

_{^{This paper reports on a project aimed at investigating teacher wellbeing in remote communities in Australia. It utilised a multiple case study methodology to investigate the lived experiences of remote Australian teachers, particularly how remote teachers simultaneously manage the wellbeing and academic needs of their students. Findings show how the challenges of working in remote places impact teacher wellbeing and provides six practical recommendations about how to better support remote teachers. There is a present need to develop a framework of remote teachers thriving, so systems and communities are not over-reliant upon teachers’ individual resilience in hard-to-staff places.}}

Implementing A Teaching Performance Assessment: An Australian Case Study, John Buchanan, George Harb, Terry Fitzgerald

Australian Journal of Teacher Education

This paper reports on the implementation of a Teaching Performance Assessment (TPA), a component of graduation recently introduced into the teaching workforce in Australia. The TPA typically requires graduates to demonstrate that they can plan, implement, assess and reflect on a series of lessons given to school students. This case study used grounded theory to analyse the initial implementation of a TPA at an Australian university, based on interviews, student focus groups, and a classroom readiness survey. We investigated the TPA’s contribution to final-year pre-service teachers’ learning and professional readiness. We conclude that the TPA, as a threshold task, is …

Professional Learning In Reading Instruction: The Influence Of Context On Engagement And Enactment, Susan Main, Deslea Konza, Mark Hackling, Graeme Lock

Australian Journal of Teacher Education

Professional learning is widely acknowledged as an effective way to improve teacher practice and, consequently, student outcomes. However, this presupposes a direct link from professional learning to the enactment of the content of professional learning in teaching. This paper explores teachers’ engagement with a continuing professional learning (CPL) program intended to improve teachers’ knowledge and practice in reading instruction. Six case study subjects, self-selected from 10 schools participating in a year‑long CPL program, provided the opportunity to explore what teachers enacted from the professional learning. This research highlighted the significance of contextual factors on how teachers engaged with and enacted …

Exploring Zimbabwean Mathematics Teachers’ Integration Of Ethnomathematics Approaches Into The Teaching And Learning Of Geometry., Gladys Sunzuma, Aneshkumar Maharaj Prof

Australian Journal of Teacher Education

This article reports on a study that explored how a group of in-service mathematics teachers integrated ethnomathematics approaches into the teaching and learning of geometry. The study used a convergent parallel mixed-methods design, which combined both quantitative and qualitative methods, to provide a deeper understanding of how the participants integrate ethnomathematics approaches into the teaching and learning of geometry. The data for the study were gathered from 40 in-service mathematics teachers through the use of questionnaires and focus group discussions. Results showed that the in-service teachers integrate ethnomathematics approaches into the teaching and learning of geometry as learning …

Safe Spaces For Enabling The Creative Process In Classrooms, Monique Fuss, Graham R. Daniel

Australian Journal of Teacher Education

Based on interviews with five creative professionals this article looks to investigate the creative experience as a source of data on how educators might create space for enabling the creative process in the classroom. Looking toward professional artists who are also committed educators provides core commentary on how to maximise creative experiences in the classroom. Whilst acknowledging the importance of physical space, the following article looks purposefully toward how to enable space as an internal state of being, with the intent toward establishing transdisciplinary discussions that stimulate and provoke creative pedagogical research across an interdependent continuum. The research concludes that …

Making A Difference To The Student Experience Through Purposeful Course Design, Lucia Zundans-Fraser, Alan Bain

Australian Journal of Teacher Education

The study described examines the student experience in a graduate inclusive education course purposefully designed to address areas of need identified. These include the need for theory to underpin course design, the need for collaborative practice, and the need to reduce the theory-to-practice gap. Throughout their enrolment and after course completion, feedback from students is presented and examined in order to determine whether these needs have been met through the design of the course. Findings suggest that the organisation of learning materials, embedded capacity-building skills, and the practical applicability of course content was highly regarded by students and contributed to …

Factors In Agency Development: A Supervisory Teaching Perspective, Paul Crowhurst, Linley Cornish

Australian Journal of Teacher Education

Promoting student agency is an emerging priority in education. Supervisory teaching is a potentially useful approach for supporting agency development. This approach includes two characteristics, namely, tutorial learning conversations between the teacher and a group of one to four students, and students learning independently for extended periods of time. Supervisory teaching lessons in three primary-school classrooms were observed over a period of five months and teachers were interviewed as part of the data collection process. Five key factors were found to support students to have more agency in their learning: independence and ownership, scaffolding, students as teachers, joyfulness, and reflection. …

Reappraising The Aitsl Professional Engagement Domain: Clarifying Social Capacity Building For School Leaders To Enhance Overall Teacher Job Satisfaction And Career Longevity, Geoffrey M. Lowe, Peter F. Prout, Christina C. Gray, Sarah Jefferson

Australian Journal of Teacher Education

The Australian Professional Standards for Teachers (AITSL, 2018) stipulate what teachers should know and do through each career stage. School leaders are complicit in promoting the Standards are met by all staff, including Professional Engagement (Standards Six and Seven). While the Standards emphasise content and pedagogical capacity building, we contend that teaching is a social enterprise. Although social capacity building is implied in the Professional Engagement domain through terms such as ‘collegiality, collaboration and dialogue’, we question the degree to which it is understood by school leaders. We ask this in light of influential studies by Waldinger (2010) and Vaillant …