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2020

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Development And Characterisation Of An Immunocompetent Three-Dimensional Oral Mucosal Infection Model, Samantha Gould Jan 2020

Development And Characterisation Of An Immunocompetent Three-Dimensional Oral Mucosal Infection Model, Samantha Gould

Other Faculty of Health Theses

Oral mucosal models are valuable tools for studying oral infection. Existing models have been implemented to study pathogen tissue invasion and resultant damage. These models fail to incorporate an innate immune component such as macrophages, essential for study of host response to infection. Macrophages exist within a regulatory to inflammatory polarisation spectrum, whereby the local microenvironment determines their activity, contributing to the overall behaviour of a tissue. Three-dimensional oral mucosal models were formed using primary (POK) or immortalized (HaCaT) keratinocytes seeded upon a human gingival fibroblast (HGF) embedded type-1 collagen matrix. Later, HaCaT based models (3DOMMs) were further developed to …

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A Concept Analysis Of Compassion In Healthcare Practice, Sarah Tobin Jan 2020

A Concept Analysis Of Compassion In Healthcare Practice, Sarah Tobin

Other Faculty of Health Theses

The subject of compassion is frequently discussed in healthcare literature but despite this, is potentially poorly understood and lacks consensus in definition. This study sought to clarify what exactly is meant by the term compassion in a healthcare context and how this is defined in both the literature and, crucially, by the behaviour and experience of healthcare staff and the experience of service users. In order to establish a definition of compassion the hybrid approach to concept analysis based on the method described by Schwartz-Barcott and Kim (2000) was adopted, this model combines comprehensive literature review with a fieldwork element …

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Intrinsic Control Strategies For Herpesvirus-Based Vaccine Vectors, Hujaz Ismail Abdulrazzaq Alqirbi Jan 2020

Intrinsic Control Strategies For Herpesvirus-Based Vaccine Vectors, Hujaz Ismail Abdulrazzaq Alqirbi

Other Faculty of Health Theses

Herpesvirus-based vectors have been used in vaccine strategies to target zoonotic diseases such as Ebola and human monkeypox, through eliciting a highly immunogenic response. We are investigating strategies to attenuate the virus and control its ability to replicate and persist, while maintaining its ability to elicit protective immune responses. In this project we have investigated three distinct and innovative means to provide intrinsic control of herpesvirus-based vectors. The first strategy is based on deletion of a gene essential for viral latency to modify persistence in vivo. Studies by Thirion et al have shown that the bovine herpesvirus 4 (BoHV-4) ORF73 …

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Hot Food Takeaways Around Schools: Can Fast Food Be Healthier?, Claire Louise Turbutt Jan 2020

Hot Food Takeaways Around Schools: Can Fast Food Be Healthier?, Claire Louise Turbutt

Other Faculty of Health Theses

Obesity is the greatest global health challenge facing this generation; over half of the adult population are overweight or obese. Calls for food environment interventions include recommendations for restriction or banning of new fast food retailers (FFRs). The Takeaway Toolkit was published by the Chartered Institute of Environmental Health and aimed to alter consumption of unhealthy takeaway food through reformulation and behavioural insights. A systematic review assessing evidence on FFRs in the environment around schools in the United Kingdom (UK) was completed and published. This revealed a research gap around food environment interventions. A study was designed to investigate “the …

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Social Connectedness And Financial Independence Strategies Supporting Nonprofit Sustainability, Christopher Edmund Maylor Jan 2020

Social Connectedness And Financial Independence Strategies Supporting Nonprofit Sustainability, Christopher Edmund Maylor

Walden Dissertations and Doctoral Studies

Leaders of nonprofit organizations (NPOs) often lack strategies to ensure the sustainability of their organizations beyond initial funding, resulting in significant risk to program continuity. Grounded in social entrepreneurship theory, the purpose of this qualitative single-case study was to explore strategies used by 3 leaders of a small NPO in the southwest region of the United States. Data were collected from semistructured interviews and a review of organizational documents. Through thematic analysis, 6 social themes emerged: optimization of business strategies, income and donor growth, program cost management, funding diversification, program licensing, and public awareness of NPO programs. The contributions to …

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Creative Technologies For Behaviour Change, Joana Galvao Gomes Da Silva Jan 2020

Creative Technologies For Behaviour Change, Joana Galvao Gomes Da Silva

Other Faculty of Health Theses

This thesis presents innovative uses of technology to support motivation, using motivational interviewing (MI) and functional imagery training (FIT) scripts developed specifically for remote delivery. MI scripts aimed to develop discrepancy, evoke solutions and promote self-efficacy. FIT scripts included multi-sensory mental imagery exercises at key points in the MI scripts. Four methods of delivery were developed: a human video-counsellor, a NAO robot programmed with Choregraphe software, a video robot counsellor for comparison with the human video-counsellor, and a life-sized two dimensional 'holographic' projection. Four empirical studies tested these developments in participants wanting to become more physically active. Study 1 (N=18) …

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Advanced Glycation End Products As A Biomarker For Accelerated Ocular Ageing And Glaucoma, Leanne Smewing Jan 2020

Advanced Glycation End Products As A Biomarker For Accelerated Ocular Ageing And Glaucoma, Leanne Smewing

Other Faculty of Health Theses

Advanced glycation end products (AGEs) have a large impact on the healthy ageing population and those diagnosed with pathology. Studies have linked AGEs to glaucomatous optic neuropathy, however there is little consensus on the role AGEs play in glaucoma development. Furthermore, it is known that diet is an exogenous source of AGEs, however it is not clear how dietary AGE (dAGE) influences tissue-bound levels in the body. The overarching theme of this thesis was to assess the impact of AGE level, measured both through diet and tissue-bound levels in the skin (skin autofluoresence, SAF), on retinal vessels and the cornea …

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Enhancing Grit In Elite Athletes Through Functional Imagery Training, Jon Rhodes Jan 2020

Enhancing Grit In Elite Athletes Through Functional Imagery Training, Jon Rhodes

Other Faculty of Health Theses

Grit has been researched across a wide variety of domains with negative correlations to drop out rates and positive associations to performance. However, there has been little to empirically change character through interventions, and even fewer in sport. A total of six studies are presented through a mixed-method approach to initially gain an understanding how grit is created, and the processes involved in developing the trait (Studies One and Two). From the phenomenological findings, a bespoke Functional Imagery Training (FIT) intervention is initially tailored to athletes and delivered (Study Three). With ceiling effects present from our performance athletes (and those …

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Influenza A Virus Infection And Innate Immunity In An Established Murine Alveolar-Like Macrophage Model, Connor Wood Jan 2020

Influenza A Virus Infection And Innate Immunity In An Established Murine Alveolar-Like Macrophage Model, Connor Wood

Other Faculty of Health Theses

Influenza is both a seasonal and occasional pandemic respiratory infection in humans, with the most vulnerable of society at the highest risk. With vaccine efficiency dropping and resistance against treatments, better understanding of the host-viral interactions is required to find novel therapy targets. Much of the current understanding for the host-viral interactions comes from epithelial cells or imperfect macrophage models. Alveolar macrophages (AMs) are crucial in the first stages of infection, but due to limited availability, true functional experiments have been impossible. By using the novel AM-like macrophage, Max Plank Institute (MPI) cells, which are available in practically unlimited numbers, …

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The Experience Of Adults With Attention-Deficit/Hyperactivity Disorder In The Workplace, Josephine Laverne Harris Jan 2020

The Experience Of Adults With Attention-Deficit/Hyperactivity Disorder In The Workplace, Josephine Laverne Harris

Walden Dissertations and Doctoral Studies

Attention-deficit/hyperactivity disorder (ADHD) has been associated with children for many decades, but it can continue into adulthood. However, little research has focused on adults with ADHD or the specific processes through which such adults mitigate the challenges they face, especially in the workplace. The purpose of this qualitative, grounded theory study was to provide a better understanding of the strategies and support systems adults with ADHD use to overcome workplace challenges. Self-efficacy theory grounded the study, allowing for an understanding of the lived experiences of adults with ADHD in the workplace. The researcher conducted 12 semistructured interviews with adults with …

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The Empire Strikes Back: Brexit, The Irish Peace Process, And The Limitations Of Law, Kieran Mcevoy, Anna Bryson, Amanda Kramer Jan 2020

The Empire Strikes Back: Brexit, The Irish Peace Process, And The Limitations Of Law, Kieran Mcevoy, Anna Bryson, Amanda Kramer

Fordham International Law Journal

No abstract provided.

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Freedom Of Expression In The Age Of Online Platforms: The Promise And Pitfalls Of A Human Rights-Based Approach To Content Moderation, Barrie Sander Jan 2020

Freedom Of Expression In The Age Of Online Platforms: The Promise And Pitfalls Of A Human Rights-Based Approach To Content Moderation, Barrie Sander

Fordham International Law Journal

No abstract provided.

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Popes Benedict Xvi And Francis On The Sexual Abuse Of Minors: Ecclesiological Perspectives, Mariusz Biliniewicz Jan 2020

Popes Benedict Xvi And Francis On The Sexual Abuse Of Minors: Ecclesiological Perspectives, Mariusz Biliniewicz

Theology Papers and Journal Articles

This article does not have an abstract.

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The Affectivity Of Good Teaching: Towards The Transformative Practice Of Possessing A 'Thinking Heart', Glenn Morrison Jan 2020

The Affectivity Of Good Teaching: Towards The Transformative Practice Of Possessing A 'Thinking Heart', Glenn Morrison

Theology Papers and Journal Articles

The aim of the article is to develop a phenomenological and theological approach to the affectivity of good teaching to foster a transformative practice of student engagement and awareness of the life of the soul as much as the mind and the heart. Drawing on the Catholic Intellectual Tradition’s search for truth in the context of the theological virtues of faith, hope and love, the article sets out to articulate what it means to possess a thinking heart of education by way of engaging seven transcendental imperatives: be spontaneous, be imaginative, be hopeful, be faithful, be pastoral, be not afraid, …

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Older Adults' Access To Medicaid's Home-And Community-Based Services, Joe Henry Horton Jan 2020

Older Adults' Access To Medicaid's Home-And Community-Based Services, Joe Henry Horton

Walden Dissertations and Doctoral Studies

As the U.S. population ages, the need for public policies regarding long-term care increases, as the need is unequal to demand. The purpose of this qualitative study was to explore and describe the role of senior service providers (SSPs) who have dealt with health policies from being responsible for the decision-making processes of implementing federal and state guidelines in Michigan on access and wait-listing of older adults for home and community-based services (HCBS). The theoretical foundation for this study was the social construction and policy design theory. The central research question sought perceptions of SSPs as to their ability to …

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Midwestern College Student Perceptions Of Police And The Power Of Names, Melessa Renee Henderson Jan 2020

Midwestern College Student Perceptions Of Police And The Power Of Names, Melessa Renee Henderson

Walden Dissertations and Doctoral Studies

The purpose of this study was to explore, understand, and describe college student perceptions of the police based on if they grew up in rural or urban communities. Three aspects of college student perception of the police covered in this study are effectiveness, fairness, and legitimacy. Effectiveness may include police responsiveness and empathy as well as crime prevention and resolution. As opposed to internal biases, fairness is more external and may include equal treatment regardless of demographic differences. Lastly, legitimacy is more philosophical and revolves around the lawfulness of state power via police over a people. Researchers acknowledge that due …

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Self-Efficacy And Burnout And Their Impact On School Counselors, Jacqueline Jacobs Jan 2020

Self-Efficacy And Burnout And Their Impact On School Counselors, Jacqueline Jacobs

Walden Dissertations and Doctoral Studies

Policymakers focused on school and mental health proposals in the wake of shooting in Newton, Connecticut. Since this incident a policy is being considered to restrict gun use and increase mental health and student support services. In 2012, the Department of Education explored five emerging issues that impact learning: (a) school discipline, (b) gender-based violence, (c) behavioral health, (d) bullying, and (e) school safety. These five issues, when they impact the learning environment, the school counselor may exhibit increased anxiety that may lead to burnout. Additionally, the school climate may be impacted by the relationship with administrators and staff. If …

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Perceptions Of Newly Licensed Registered Nurses About Homecare As A Practice Area, Tamara M. Kelley Frazier Jan 2020

Perceptions Of Newly Licensed Registered Nurses About Homecare As A Practice Area, Tamara M. Kelley Frazier

Walden Dissertations and Doctoral Studies

The demand for competent nurses working in a home care setting continues to grow because of decreased length of stay in hospitals and population needs for chronic care management when homebound. Nursing educational programs introduce students to community health and home care nursing, which could influence a student nurse's choice of home health care as an initial practice setting. This qualitative study examined the perceptions of newly licensed registered nurses (NLRNs) about home care as an initial practice area. Ten NLRNs not working in home health care areas responded to 16 open-ended interview questions that were based on the career …

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Examining A Dynamic Leadership Approach That Influences Job Satisfaction In Dynamic And Stable Environments, Francois Kammoe Jan 2020

Examining A Dynamic Leadership Approach That Influences Job Satisfaction In Dynamic And Stable Environments, Francois Kammoe

Walden Dissertations and Doctoral Studies

Effectively managing the turnover of qualified staff has become a major challenge for managers. In this dynamic business era, companies in various industries experience an annual staff turnover rate of at least 10%. Scholars have linked employee turnover to job dissatisfaction and inadequate leadership styles. A quantitative non-experimental correlation study was conducted to examine the relationship between servant, transactional, and transformational leadership styles and employee job satisfaction as well as the moderating and mediating mechanisms in which this relationship occurs. The theoretical framework for this study included Harber and McMaster's dynamic leadership approach, the adaptable emphasis leadership model by Staats, …

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Child Witchcraft Accusations In Kinshasa, The Democratic Republic Of Congo, Edmond Kesseh Jan 2020

Child Witchcraft Accusations In Kinshasa, The Democratic Republic Of Congo, Edmond Kesseh

Walden Dissertations and Doctoral Studies

Child witchcraft accusations, which represent a comparatively new phenomenon in Kinshasa, Democratic Republic of Congo, have caused tens of thousands of children aged 5-10 years to be abused, tortured, ostracized, stigmatized, and thrown out of family homes into the streets. The purpose of this phenomenological study was to explore the perceptions of staff of local nongovernmental organizations (NGOs), international organizations, and other child advocacy groups who worked with young children accused of witchcraft concerning how their efforts and collaboration with the government influenced the problem. Critical theory and an attachment conceptual framework were used to analyze the effectiveness of existing …

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Understanding Calculus Through Maple-Based Dynamic Visualization Tools, Segla Kokou Kossivi Jan 2020

Understanding Calculus Through Maple-Based Dynamic Visualization Tools, Segla Kokou Kossivi

Walden Dissertations and Doctoral Studies

First-year college students experience difficulties in understanding the concepts of derivatives and integrals. At the postsecondary level, the use of static visualization and other traditional instruction delivery methods often are unable to meet students' needs in calculus. This problem is current and essential in the field of education and needs consideration to enhance the method of teaching calculus. The rationale for this study was to scrutinize the effects of Maple dynamic visualization instructional activities, within the framework of the animation-visualization theory, on students' conceptual and procedural understanding of differential and integral calculus. The usage of a quantitative 2x2 factorial pretest-posttest …

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Exploring Destination Imagination Alumni Perceptions Of 21st-Century Skills And Workforce Readiness, Sharon Kovalevsky Jan 2020

Exploring Destination Imagination Alumni Perceptions Of 21st-Century Skills And Workforce Readiness, Sharon Kovalevsky

Walden Dissertations and Doctoral Studies

Workplace requirements are vastly different from the past due to rapid changes in technology and globalization, and they require graduates to have well-developed 21st-century skills and innovation strategies. The problem addressed in this study was the lack of understanding of how 21st-century skills that alumni learned through academic extracurricular experiences informed their early career and workforce readiness. The purpose of this qualitative study was to explore how Destination Imagination (DI) alumni perceived that the 21st-century skills they learned as part of their academic extracurricular experiences informed their early career readiness. The study was grounded by the 3 constructs of work …

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Strategies For Hiring People With Disabilities To Prevent A Skilled Worker Shortage, Andreas Kyprianou Jan 2020

Strategies For Hiring People With Disabilities To Prevent A Skilled Worker Shortage, Andreas Kyprianou

Walden Dissertations and Doctoral Studies

Many business sectors are currently facing challenges in the labor market and will need to address inefficiencies in their recruitment and retention strategies. Restaurant managers who lack strategies for recruiting nontraditional staff, such as people with disabilities, risk declining competitiveness because of this labor shortage. Grounded in stakeholder theory, the purpose of this multiple case study was to explore strategies restaurant managers use to recruit and hire people with disabilities to prevent or address skilled worker shortages. The participants comprised 7 quick service restaurant (QSR) franchisees and managers from the same QSR brand in Canada with previous experience recruiting staff …

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Public Policy Response To Violence: Case Study Of Boko Haram Insurgency In Nigeria, Emmanuel Baba Mamman Jan 2020

Public Policy Response To Violence: Case Study Of Boko Haram Insurgency In Nigeria, Emmanuel Baba Mamman

Walden Dissertations and Doctoral Studies

The violence of the Boko Haram insurgency in Nigeria has generated an increased need for public policy responses. Nigerian authorities and community stakeholders have attempted myriad responses to the challenges created by Boko Haram. However, there is a poor understanding of policy frameworks for handling the Boko Haram violence on the immediate, medium-term, and long-term dimensions. The purpose of this qualitative case study was to improve the understanding of the public policy measures that may help to address the Boko Haram challenge. John Burton's theory of human needs provided a theoretical foundation for the study. Purposive sampling technique was used, …

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Relationship Between Transformational Leadership, Employee Satisfaction And Job Performance Of Virtual Workers, Alice Miller Jan 2020

Relationship Between Transformational Leadership, Employee Satisfaction And Job Performance Of Virtual Workers, Alice Miller

Walden Dissertations and Doctoral Studies

The effects of leaders on virtual employees job satisfaction and job performance is essential to virtual team success. As virtual workplaces continue to evolve, there is a need to focus research on how leaders affect virtual employees. Previous research has indicated that understanding the relationship between perceived leadership and job satisfaction is crucial as it helps create a motivated and effective workforce. However there remains an essential gap in current literature regarding leadership effectiveness on job satisfaction and job performance of virtual workers. The population group for this study consisted of 70 randomly selected virtual employees. Participants of the study …

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Integrated Threat Management: An Alternative Approach To Regional Security System For Ecowas, Farouck Mohammed-Bashar Jan 2020

Integrated Threat Management: An Alternative Approach To Regional Security System For Ecowas, Farouck Mohammed-Bashar

Walden Dissertations and Doctoral Studies

The onset of new and emerging threats to peace and security in West Africa has added another layer of threat to security in West Africa. There is a need for research on the interconnectedness among existing and new and emerging threats to security in the region. The purpose of this study was to explore the Economic Community of West African States' (ECOWAS') approach to its regional security management strategy. The punctuated equilibrium theory and policy feedback theory were used to conceptualize the problem within the context of ECOWAS' policy inertia and the wide range of security and sociopolitical dynamics in …

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Reported Literacy Engagement Among Low-Income Parents And Their Children., Olugemi Ojo Jan 2020

Reported Literacy Engagement Among Low-Income Parents And Their Children., Olugemi Ojo

Walden Dissertations and Doctoral Studies

Little is known about literacy engagement between low-income parents and their preschool children, although it may affect children's language development and later school achievement. The purpose of this qualitative study was to examine shared reading interactions among low-income parents and their children. The research questions addressed the lexical diversity of books read and the shared book reading experience of preschool children as reported by their low-income parents. The conceptual framework was based on the work of Hart and Risley, who proposed that the extent and value of literacy environment and collaboration during shared book reading are linked to the socioeconomic …

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Education To Improve Health For Rural Africa American Women With Diabetes, Monique Deidre Pendleton Jan 2020

Education To Improve Health For Rural Africa American Women With Diabetes, Monique Deidre Pendleton

Walden Dissertations and Doctoral Studies

Diabetes (DM) is the 7th leading cause of death in the United States. Minorities like Hispanics and African Americans (AA) are at greater risk of developing DM. The prevalence and outcomes affecting diabetes are attributed to socioeconomic status, sex differences, ethnic, cultural, and religious status. Diabetes-related mortality is a major health problem in AA in rural America. The focus for this project was to identify the best evidence regarding educational counseling on lifestyle modifications that positively impact adult AA women with diabetes living in Rural America. The social-ecological theory and health belief model informed this project because these models incorporate …

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Exploring The Impacts Of Workplace Loneliness On Criminal Justice Senior Leaders, Johanna Papa Jan 2020

Exploring The Impacts Of Workplace Loneliness On Criminal Justice Senior Leaders, Johanna Papa

Walden Dissertations and Doctoral Studies

This phenomenological qualitative study aimed to explore the impacts of workplace loneliness on senior leaders of various criminal justice organizations. The theoretical framework used was Descartes' views of the self-concept theory, which explained how individuals defined and described themselves within a social context. Using purposive sampling and semistructured telephone, and email interviews of 16 criminal justice senior leaders from the Washington, D.C. metropolitan area, this research was conducted to answer the overarching question of this study. Workplace loneliness was a professional hazard. The key findings revealed that at least 87% of the criminal justice senior leaders reported feeling or have …

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Parental Characteristics And Lead Knowledge In The Minimization Of Environmental Lead Exposure, Trina Yvette Redford Jan 2020

Parental Characteristics And Lead Knowledge In The Minimization Of Environmental Lead Exposure, Trina Yvette Redford

Walden Dissertations and Doctoral Studies

A method for guiding lead intervention and minimizing lead exposures in Philadelphia, Pennsylvania (PA) is through understanding the relationship between lead knowledge and parental characteristics such as gender, age, income, marital status, and education attainment. Parental characteristic may play a significant role in the identification of population groups where knowledge pertaining to lead exposure is inadequate. Through awareness and intervention, preventive measures can be implemented to minimize and eliminate lead exposure. The theoretical concept used in this quantitative study was Krieger ecosocial theory. The ecosocial theory provides guidance and analyzes differences in existing health relationships, especially those with biological and …

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