Digital Commons Network^™

Effects Of Acculturation On Stigma And Knowledge In Relation To Autism Spectrum Disorder Amongst Latino Populations, Monica M. Abdul-Chani

All ETDs from UAB

In the United States, Latino children receive autism diagnoses at a later age compared to non-Latino Black and non-Latino White children (Jo et al., 2015), have the highest rate of misdiagnosis (Magaña, Lopez, Aguinaga, & Morton, 2013), and are more likely to be under-identified (Pedersen et al., 2012). This study examines the presentation of ASD stigma and potentially influencing factors in Latino populations. Through an online survey, 97 Latino and 115 non-Latino White participants were randomly assigned to read one of two vignettes depicting characteristics and symptoms of ASD in lay terms for either their own child (self) or a …

A Critical Narrative Inquiry Into The Lived Experiences Of African American Male K-12 Novice Educators In An Urban School District In Central Alabama, Herbert Leon Blackmon

All ETDs from UAB

The purpose of this study is to share how African American/Black male K-12 novice educators navigated their own educational journey to become K-12 educators in an urban school district in central Alabama. An urban school district was identified from findings from the Census Bureau and had a school that sat inside an urbanized area and inside a principal city with a population of 250,000 or more. Because of its size, urban school districts were diversified with a large enrollment and an increased number of minority students. By using a qualitative, critical narrative inquiry approach, participants were able to recount their …

Suicidality, Stigma, And Online Help-Seeking, Mercedes Tarasovich

All ETDs from UAB

Suicide rates in the U.S. have been climbing for over two decades, driving increased suicide prevention efforts nationwide. The population of those who have experienced suicidality or attempted suicide are estimated to be at least 25 times the suicide death rate and are not as well-researched. Stigma regarding the utilization of mental health care services and a fear of institutionalization may affect help-seeking behaviors for individuals who have experienced suicidality, potentially prompting use of more anonymous online sources of support. In this study, I aimed to research whether suicidality and perceived mental health stigma can lead to increased use of …

There And Back Again: A Rhetorical Journey From Oppression To Exclusion, Sally Anne Perz

All ETDs from UAB

This thesis addresses parallels between the rhetoric of contemporary secessionists and the arguments surrounding the rise and fall of Jim Crow laws which maintained segregation for decades. Cities like Gardendale, Alabama and Baton Rouge, Louisiana make uncanny arguments in their attempts to break-away from county school systems, promoting new and improved propaganda, alluding to “separate but equal” in their attempts to separate for the good of their communities. Despite years of multicultural instruction, schools are fighting the same battle, on the same turf, generations later—some cities surrounding Birmingham and across the country add a new twist on the same white …

"Autism Friendly Alabama": Identifying Key Criteria To Support An Inclusive Environment, Caro C. Wolfner

All ETDs from UAB

The present study examined potential supports and barriers towards an inclusive or ‘autism friendly’ environment from the perspectives of family members of individuals with ASD (n=127) and adults with ASD (n=16). Groups did not differ on endorsement of importance for any of the criterion, except for crowds (p<0.05). The highest ranked quality by Caregivers/Family members were knowledgeable and helpful staff’ (32.5 percent) and attitudes (22.5 percent). The ASD group ranked knowledgeable and helpful staff (30 percent) and crowds (30 percent) as the most important quality. Qualitative data showed that modulated sensory environment, knowledgeable and trained staff’; access to supports, and awareness of locations & as emerging themes for ‘autism friendly’ environments. The present study represents an approach involving research, education and advocacy to provide evidence-based criteria that will be used as a standard for ASA’s Autism Friendly Alabama program. With criteria identified, stakeholders can move forward with completing subsequent goals for the initiative, such as program implementation and evaluation.

A Cephalometric Study Of The Effects Of Class Ii Malocclusion Correction Utilizing The Carriere® Motion 3d Appliance And Essix Retainer, Julie Dean

All ETDs from UAB

Objective: The purpose of this study is to determine the dental and skeletal effects of Class II malocclusion correction with a Carriere® Motion 3D appliance and lower Essix retainer for anchorage, as compared to best-matched controls. Methods: This is a retrospective case-control cephalometric study uses pre- and post-distalization lateral cephalometric images from 44 (32 female, 12 male, average age 13y 7m) class II patients treated with a Carriere® Motion 3D appliance and lower Essix retainer. These films were analyzed to determine treatment effects and compared with 35 (17 female, 18 male, average age 13y 3m) untreated controls from a historical …

Molecular Regulation Of Glioblastoma Spatial Heterogeneity And Therapeutic Resistance, Soniya Bastola

All ETDs from UAB

Glioblastoma multiforme (GBM) is a highly invasive, highly vascularized, and heterogeneous malignant tumor of the brain. Due to the highly infiltrative phenotype of GBM, surgery often leaves behind residual tumor cells. In many cases, recurrence occurs close to the surgical margin suggesting the role of these remaining cells in promoting tumor aggressiveness. Rapidly growing tumor creates subsequent hypoxic, and hypovascular core due to limited nutrients, whereas tumor cells in the leading edge have access to nutrients from vasculature enriched microenvironment. Studies have identified the cellular and molecular heterogeneity between the tumors in core and edge. Still, their mechanisms of intercellular …

Tau-Dependent Regulation Of Network Hyperexcitability By Alzheimer’S Disease Risk Gene Bin1, Yuliya Voskobiynyk

All ETDs from UAB

Alzheimer’s disease (AD) is the leading neurodegenerative disorder that affects an astonishing 5.8 million Americans, a number projected to reach 14 million by the year 2050. While only about 1% of all AD cases are caused by mutations in APP, PSEN1, and PSEN2, the cause of sporadic AD remains unknown. Variations in several risk genes have been proposed to contribute to the development of sporadic AD cases. Since, currently, there are no disease-modifying therapies for families affected by AD and multiple anti-amyloid-beta therapies failed in clinical trials, determining how these risk genes contribute to the development of AD is crucial …

A Multiple Case Study On The Experiences And Perspectives Of Instructional Coaches Supporting Teachers With The Literacy Instruction Of Historically Marginalized Populations, Kristie Basila Williams

All ETDs from UAB

This qualitative multiple case study explored the experiences and perspectives of instructional coaches that support teachers with the literacy instruction of students from historically marginalized populations through the lens of the following three theoretical frameworks: the partnership approach, critical literacy, and culturally relevant pedagogy. The three participants involved in the study all came from the same district but different schools and were recruited based on the criteria of being an instructional coach in a middle school that has more than 51% of students from historically marginalized populations, as identified by the state’s department of education website. The data collected included …

Toward The Mechanism Underlying Latanoprost- And Benzalkonium Chloride-Induced Meibomian Gland Dysfunction In Patients Treated For Glaucoma, Jillian Ziemanski

All ETDs from UAB

Once thought to be no more than a vexing eye condition, ocular surface disease (OSD) is now being viewed as a differentiating factor between sight and no sight. In the setting of glaucoma, OSD can interfere with treatment success, potentially allowing the visually devastating pathology of glaucoma to plow onward with little restraint. Compounding the clinical challenge is the growing awareness that glaucoma-associated OSD appears to be iatrogenically induced by topical ophthalmic medications. Daily, topical instillation of preserved prostaglandin analogs (PGAs), the most common first-line treatment for glaucoma, has been linked to a variety of OSD subtypes, including meibomian gland …

Symbolic Annihilation, The Politics Of (Mis)Representation, And The Stress And Health Of Millennial Black Women, Chenoia Nicole Bryant

All ETDs from UAB

The (mis)representation of Black populations in media has been extensively explored and critiqued by several scholars. From their introduction into media through radio to their visi-bility in television and news, the tropes of Black womanhood have carried over from colo-nialist perspectives to present day. Considering race and gender as cultural structures con-straining Black women through the assignment of stereotypical scripts, it is important to consider how, when and where Black women’s agency enters. Negative racialized and gendered stereotypes are informed by culture at large, but Black women’s agency impacts the interpretation of these (mis)representations, offering space for both conformity and …

Understanding Adolescent Sexual Health Through Exploration Of Their Perceptions, Behaviors, And Beliefs, Jessica L. Corcoran

All ETDs from UAB

Adolescents in the United States disproportionately experience adverse sexual health outcomes compared to adolescents in other developed countries. The purpose of this dissertation is to provide an in-depth examination of adolescent sexual health through the generation of three manuscripts. The first manuscript will provide an integrative review of adolescents’ perceptions of sexual health education programs. The second manuscript will illuminate the five-year trends in adolescent chlamydia rates by region, race, and sex. The third manuscript will provide a qualitative analysis from interviews with African American adolescent females in the southern U.S. Manuscript one reviewed studies from 2008 to 2019. The …

Developing An Assessment Of Reading Impairment And Its Impact On Occupational Performance In Older Adults With Glaucoma In A Metropolitan Area Of The Southeastern Us: A Mixed Methods Approach, Robin Deacy

All ETDs from UAB

According to the United States Administration on Aging (AOA, 2014), the population of individuals over 65 will be 98 million by the year 2060, doubling its 2014 estimates. As our population ages, the prevalence of glaucoma increases. Vision loss resulting from glaucoma can limit participation in valued occupations including engagement in reading. It has long been thought that mobility issues and glare sensitivity were the main factors that characterized glaucoma. In the late 1990s and early 2000s researchers began to examine quality of life (QoL) in those with glaucoma. It was during these early QoL studies that the first reports …

Obesity-Induced Immune Dysfunction: Implications For Anti- Tumor Immunity And Immunotherapeutic Efficacy, Justin Tyler Gibson

All ETDs from UAB

In the US, nearly 40% of adults have obesity. Further, obesity is known toincrease the risk for development, recurrence, and mortality associated with multiple types of cancer. However, despite such high prevalence, the impact of excess body weight on anti-tumor immunity and response to immunotherapeutics remains poorly and incompletely understood. In order to address these deficiencies, we have utilized multiple approaches to study obesity-associated perturbations in the immunogenetic, soluble protein, and cellular profiles of mice bearing mammary tumors and treatment naive human subjects with clear cell renal cell carcinoma (ccRCC). In a pre-clinical murine model of breast cancer, we find …

Confederate Monuments As Badges Of Slavery, Alexander Tsesis

Kentucky Law Journal

No abstract provided.

Why Use A Hammer When A Scalpel Will Do? Suggestions For Fairer Juvenile Plea Bargaining In Kentucky, Aaron Wallace Meek

Kentucky Law Journal

No abstract provided.

Table Of Contents For Volume 109, Issue 1, Kentucky Law Journal

Kentucky Law Journal

No abstract provided.

Hyperreal: Law And The Interpretation Of Visual Media, Amy L. Landers

Kentucky Law Journal

No abstract provided.

The Army's G-Rap Fiasco: How The Lives And Careers Of Hundreds Of Innocent Soldiers Were Destroyed, Jeffrey F. Addicott

Faculty Articles

The purpose of this article is three-fold. First, this article seeks to explore the legal and policy ramifications of the CID's multi-year criminal investigation, which targeted vast numbers of innocent Army National Guard and Army Reserve personnel for alleged criminality as contract employees in the G-RAP or AR-RAP.

Second, this article aims to highlight the CID's longstanding practice referred to as "titling"-of refusing to delete from their system of records those individuals that are subsequently cleared of any wrongdoing by their commands. This highly dubious administrative practice was particularly devastating to the hundreds of innocent and fully exonerated participants in …

Copper Dependent Inhibitors Subvert Common Resistance Mechanisms In Staphylococcus Aureus And Inhibit Crucial Metabolic Pathways, Cameron Crawford

All ETDs from UAB

The effective antibiotic pool is shrinking with antibiotic resistance a constant problem that threatens to make our current therapies obsolete. To combat this, new drug screening methodologies are required since the traditional drug screens are offering limited results or only improvements upon current treatments. This work expands upon the idea that transition metal toxicity can be preferentially targeted towards bacteria. Specifically, the focus is on copper dependent inhibitors that quickly work to eliminate Staphylococcus aureus. S. aureus is a particularly threatening bacteria with high strain variability, a litany of survival and virulence factors, and multiple drug resistance mechanisms that are …

Quality Of Life, Reading And Accommodation In Children With Low Vision, Dawn Kissner Decarlo

All ETDs from UAB

Childhood permanent, uncorrectable vision impairment (VI) is rare, yet it is a public health burden as the impairment lasts a lifetime. Vision impairment describes decreased vision that affects everyday activities. Acuity cut-points commonly used include 20/40, 20/60 or 20/70. Blindness often refers to legal blindness (best corrected visual acuity of 20/200 or worse or a visual field less than 20 degrees). Children with VI often have hereditary conditions such as albinism, optic atrophy and retinal degenerations and are different in many ways than adults with VI. The majority have conditions with onset at or near birth and as a result …

Protective Effects Of Thioredoxin Reductase Inhibition In The Murine Lung: The Regulation And Contribution Of Heme Oxygenase-1, Katelyn Louise Dunigan-Russell

All ETDs from UAB

Endogenous antioxidant responses defend the lung against oxygen toxicity. In premature neonates, oxygen toxicity and impaired antioxidant defenses contribute to the development of bronchopulmonary dysplasia (BPD), the leading cause of long-term morbidity among premature infants. In adults, oxygen toxicity and impaired antioxidant defense contributes to the pathogenesis of acute lung injury (ALI). Acute Respiratory Distress Syndrome (ARDS), a severe form of ALI, can cause permeant lung damage and mortality. Our lab has established that pharmacologic thioredoxin reductase-1 (TXNRD1) inhibition attenuates lung injury in murine BPD and ALI models. The protective effects of TXNRD1 inhibition are mediated by the activation of …

Parent Reactions To Sexual And Gender Identity Disclosure Events In The Deep South, Allison Claire Estep

All ETDs from UAB

Disclosure of sexuality by coming out is a central part of the process of self-identification for LGBT youth (Denes & Afifi, 2014). Parents’ initial response to their child’s coming out is linked to parent-child relationship satisfaction and if the child will later feel the need to come out for a second time or to clarify their sexual identity (Denes et al. 2014). Parental acceptance of LGBT youth’s disclosure has been linked to higher self-esteem and lower rates of suicidal tendencies, depression, and substance abuse (Needham & Austin, 2010; Ryan, Russell, Huebner, Diaz, & Sanchez, 2010). Current research regarding parent reactions …

Contribution Of Adaptive Immune Responses In Chronic Lung Diseases, Thi Kim Tran-Nguyen

All ETDs from UAB

Immune dysregulation is a hallmark of various chronic lung diseases such as Chronic Obstructive Pulmonary Diseases (COPD) and Idiopathic Pulmonary Fibrosis (IPF). Previous studies in our lab have shown evidences of autoimmunity such as increases in autoantibodies, abnormal T cell profile, immune complex deposition and the presence of ectopic lymphoid structures in the lung of these patients. This thesis consolidates two separate projects about various aberrant immune responses in these diseases. The first project identified Glucose-Regulated-Protein 78 (GRP78) as the common autoantigen in COPD and characterized how GRP78 autoantibodies may increase COPD mortality via its atherogenic effects. I demonstrated that …

Espad 2019 Ireland: Results From The European Schools Project On Alcohol And Other Drugs In Ireland, Salome Sunday, Sheila Keogan, Joan Hanafin, Luke Clancy

Books / book chapters

The ESPAD Ireland 2019 Report is the seventh Irish data-collection wave of the European Schools Project for Alcohol and Other Drugs (ESPAD) carried out in Ireland.Data included in the sample reported here and submitted to ESPAD Europe consists of survey results from 1967 students born in 2003, who were 15-16 years old at the time of the survey which was performed in a sample of Irish schools from March to June 2019. These serial data sets enable us to monitor trends in alcohol, tobacco, gaming, internet usage as well as a number of other behaviors including illicit drug usage such …

An Investigation Into The Application Of Raman Spectroscopy For Cervical Cancer Screening, Damien Traynor

Doctoral

aman spectroscopy is a powerful tool that has the potential to be, used for cervical cancer screening. It is a label-free, low-cost method providing a biochemical fingerprint of a given sample. The objective of this thesis was to address issues associated with the application of Raman spectroscopy for cervical cancer screening and to demonstrate the potential for triage of HPV positive cases. The first study investigated hormonal effects due to the menstrual cycle, the use of hormone- based contraceptives (HC) and the onset of menopause on Raman spectra of cervical cells and determined if these changes would affect the ability …

Framing “L’Âme Des Personnages”: Performance And Affect In Jacques Feyder’S Pension Mimosas (1935), Barry Nevin

Articles

Although Jacques Feyder's authorial control over his productions and his direction of actors constituted two of the most widely appreciated aspects of his approach to filmmaking during his own lifetime, the impact of each on his mise en scene has received little critical attention. This article aims to remedy this oversight by linking both aspects in three stages: first, drawing on contemporary periodicals, recollections of Feyder's performers and his own writings, it illustrates Feyder's preoccupation with the creation of in-depth psychological portraits through his actors; second, focusing on Pension Mimosas (1935), it demonstrates that Feyder's technical style, although aligned closely …

(Re)Visions Of The Outre-Mer: Looking At The Male Gaze In Jacques Feyder’S Le Grand Jeu (1934), Barry Nevin

Articles

Cinéma colonial is regarded by certain scholars as a highly conventionalised and commercialised film practice that grants spectators a sense of control over the potentially threatening colonial Other, and Belgian director Jacques Feyder has been subject to particularly harsh criticism in this regard. This article argues that Feyder’s Le Grand Jeu (1934), which depicts a young legionnaire’s relationship with a cabaret singer who bears an uncanny resemblance to a previous lover who jilted him in Paris, challenges dominant tendencies in portrayals of gender and colonialism in French cinema of the 1930s. Drawing on the relationship between Laura Mulvey’s theorisation of …

Evolution Of Growth Rates And Interspecies Interactions Of Prochlorococcus And Alteromonas Under Ocean Acidification Conditions, Matthew Kuhl

All ETDs from UAB

Prochlorococcus is an unusually small and numerous genus of marine cyanobacteria which is thought to contribute 8.5% of marine primary production. Prochlorococcus lacks a gene for catalase, resulting in significant sensitivity to stress from reactive oxygen species (ROS), particularly hydrogen peroxide. Prochlorococcus is known to rely on other species of microbes in the ocean to degrade ROS, such as Alteromonas, a heterotrophic “helper” bacterium with which it is frequently co-located. However, it has been observed that Y2100 predicted ocean acidification conditions (800 ppm atmospheric CO2) reduce catalase production by Alteromonas strain EZ55, increasing oxidative stress on Prochlorococcus strain MIT 9312. …

An Examination Of Welding Inputs And Outputs For The High Frequency Welding Of Steel Pipe, Lindsey Mccall

All ETDs from UAB

Oil and natural gas touch the lives of most people around the world each day in one way or another. As the demand for these products has risen, so has the need for more pipelines. The pipelines that transport oil and natural gas must meet a strict set of criteria to ensure safety. These criteria include mechanical properties and nondestructive testing requirements. The purpose of this study was to determine how to correlate welding inputs and outputs to weld quality, specifically the occurrence of welding discontinuities that are detrimental to the pipe and mechanical properties. The three conclusions of this …