Digital Commons Network^™

Adaptive Courseware Implementation: Investigating Alignment, Course Redesign, And The Student Experience, Patricia O'Sullivan, Janelle Voegele, Tonya Buchan, Raiza Dottin, Kari Goin Kono, Misty Hamideh, Wendy S. Howard, Jennifer Todd, Lee Tyson, Stanley Kruse, Johannes De Gruyter, Kevin Berg

Current Issues in Emerging eLearning

In this paper, four institutions share student and faculty feedback on the implementation of adaptive courseware through a common case study: biology for undergraduate non-majors. Additionally, each institution has provided a second case study of their choice. Together, researchers at Colorado State University in Fort Collins, CO, Portland State University in Portland, OR, University of Central Florida in Orlando, FL, and the University of Mississippi in Oxford, MS consider student perception of the benefits to the implementation of adaptive courseware, and how the deliberate alignment between adaptive courseware and course organization and structure impacts student experience. This paper highlights the …

Modeling Residence Time Distribution Of Chromatographic Perfusion Resin For Large Biopharmaceutical Molecules: A Computational Fluid Dynamic Study, Kevin Vehar

KGI Theses and Dissertations

The need for production processes of large biotherapeutic particles, such as virus-based particles and extracellular vesicles, has risen due to increased demand in the development of vaccinations, gene therapies, and cancer treatments. Liquid chromatography plays a significant role in the purification process and is routinely used with therapeutic protein production. However, performance with larger macromolecules is often inconsistent, and parameter estimation for process development can be extremely time- and resource-intensive. This thesis aimed to utilize advances in computational fluid dynamic (CFD) modeling to generate a first-principle model of the chromatographic process while minimizing model parameter estimation's physical resource demand. Specifically, …

Designing And Teaching Adaptive+Active Learning Effectively, Peter Van Leusen, James Cunningham, Dale P. Johnson

Current Issues in Emerging eLearning

To fulfill the promise of providing all learners with access to education, institutions of higher education are exploring personalized learning for individuals with different skills, abilities, and interests. These universities have turned to an instructional model that combines adaptive courseware and learner-centered instruction. This is often referred to as active learning. Despite growth in adaptive courseware and generous support through national organizations, successful implementation of adaptive systems is mixed (SRI Education, 2016). This article highlights the need for a systems approach and illustrates this approach through design and pedagogy decisions that have contributed to the success of adaptive learning at …

Core Commitments For Field Trials Of Gene Drive Organisms, Kanya C. Long, Luke Alphey, George J. Annas, Cinnamon S. Bloss, Karl J. Campbell, Jackson Champer, Chun-Hong Chen, Amit Choudhary, George M. Church, James P. Collins, Kimberly L. Cooper, Jason A. Delborne, Owain R. Edwards, Claudia I. Emerson, Kevin Esvelt, Sam Weiss Evans, Robert M. Friedman, Valentino M. Gantz, Fred Gould, Sarah Hartley, Elizabeth Heitman, Janet Hemingway, Hirotaka Kanuka, Jennifer Kuzma, James V. Lavery, Yoosook Lee, Marce Lorenzen, Jeantine E. Lunshof, John M. Marshall, Philipp W. Messer, Craig Montell, Kenneth A. Oye, Megan J. Palmer, Philippos Aris Papathanos, Prasad N. Paradkar, Antoinette J. Piaggio, Jason L. Rasgon, Gordana Rašić, Larisa Rudenko, J. Royden Saah, Maxwell J. Scott, Jolene T. Sutton, Adam E, Vorsino, Omar S. Akbari

United States Department of Agriculture Wildlife Services: Staff Publications

We must ensure that trials are scientifically, politically, and socially robust, publicly accountable, and widely transparent.

Gene drive organisms (GDOs), whose genomes have been genetically engineered to spread a desired allele through a population, have the potential to transform the way societies address a wide range of daunting public health and environmental challenges. The development, testing, and release of GDOs, however, are complex and often controversial. A key challenge is to clarify the appropriate roles of developers and others actively engaged in work with GDOs in decision-making processes, and, in particular, how to establish partnerships with relevant authorities and other …

Functionalized Materials From Atom Transfer Radical Processes, Sean Fischer

Electronic Theses and Dissertations

This work is focused on the synthesis, characterization, and application of functionalized materials prepared from atom transfer radical processes. Atom transfer radical processes encompass both atom transfer radical addition (ATRA) and polymerization (ATRP) reactions, both of which are catalyzed by ppm amounts of copper complexes. The synthetic efforts of ATRA include increasing adduct selectivity through optimization of reaction conditions to generate small molecules in high to moderate yields. ATRA provides retention of the halogen moiety, which is an attractive functional group that can be further modified with other transformations. Specifically, the copper-catalyzed azide-alkyne [3+2] cycloaddition (CuAAC) allows for the realization …

Winter Commencement: December 18, 2020, University Of North Dakota

UND Commencement Programs

UND Winter Commencement program from December 18, 2020.

Direct Measurement Of The Cosmic-Ray Carbon And Oxygen Spectra From 10 Gev/ N To 2.2 Tev/ N With The Calorimetric Electron Telescope On The International Space Station, O. Adriani, Y. Akaike, K. Asano, Y. Asaoka, M. G. Bagliesi, E. Berti, G. Bigongiari, W. R. Binns, M. Bongi, P. Brogi, A. Bruno, J. H. Buckley, N. Cannady, G. Castellini, C. Checchia, M. L. Cherry, G. Collazuol, K. Ebisawa, H. Fuke, S. Gonzi, T. G. Guzik, T. Hams, K. Hibino, M. Ichimura, K. Ioka, W. Ishizaki, M. H. Israel, K. Kasahara, J. Kataoka, R. Kataoka, Y. Katayose, C. Kato, N. Kawanaka

Faculty Publications

In this paper, we present the measurement of the energy spectra of carbon and oxygen in cosmic rays based on observations with the Calorimetric Electron Telescope on the International Space Station from October 2015 to October 2019. Analysis, including the detailed assessment of systematic uncertainties, and results are reported. The energy spectra are measured in kinetic energy per nucleon from 10 GeV/n to 2.2 TeV/n with an all-calorimetric instrument with a total thickness corresponding to 1.3 nuclear interaction length. The observed carbon and oxygen fluxes show a spectral index change of ∼0.15 around 200 GeV/n established with a significance >3σ. …

Effectiveness Of An Interdependent Group Contingency With Randomization Using The Ipad, Chelsea Gyke

Electronic Theses and Dissertations

Classroom management, although considered one of the essentials of the optimal learning experience, is often a challenge for teachers. Certain classroom management strategies, such as group contingency interventions and token economies, are evidence-based strategies to aid teachers in gaining successful management of the classroom. The utilization of Class Dojo, a popular classroom management website, as a mechanism to implement an interdependent group contingency (IGC) intervention with randomized components may increase both the effectiveness of the intervention and the social validity of the intervention when compared to a manual implementation.

Participants included students in an elementary school self-contained special education classroom …

Accurate Quantitation Of Hexavalent Chromium For Reference Standard Certification And Quality Control Testing Using Speciated Isotope Dilution Mass Spectrometry, James E. Henderson

Electronic Theses and Dissertations

The ability to perform accurate, repeatable, and defensible elemental and molecular speciated analysis is immensely significant for measurements that support human health, environmental science, and industry. This is especially true since trivalent chromium [Cr(III)] is necessary for proper nutrition, while hexavalent chromium [Cr(VI)] is extremely toxic, genotoxic, and carcinogenic. The main challenges associated with speciated analysis are related to reactive species that are continuously transformed or converted to other species during sample processing. Accurate determination of Cr(III) and Cr(VI) species require a method that is capable of monitoring and correcting for interconversion, bias, and instrumental error. Traditional quantitative methods, such …

Atom Transfer Radical Processes: From Catalyst Design To Polymer Synthesis, Characterization, And Application, Michael Novak

Electronic Theses and Dissertations

Due to the toxicity of heavy metals and their prevalence in the environment there exists a need to develop highly active transition metal catalysts ultimately reducing the amount needed for chemical transformations. Additionally, there is interest in the scientific community for creating new materials that can remove these pollutants from industrial wastewater prior to its release into the environment. The work presented here focuses on the reduction and removal of heavy metals from industrial hazardous waste by designing novel highly active catalysts and developing polymeric adsorbents.

Highly active catalyst complexes consisting of novel hybrid ligands, 2-(dimethylamino)ethyl-bis-[2-(pyridylmethyl)amine] (M1-T2), and bis[2-(dimethylamino)ethyl]-2-(pyridylmethyl)amine (M2-T1), …

Fluoride Removal With Augmented Bentonite In Drinking Water And Community Perceptions In Arusha, Tanzania, Kara Okular

Electronic Theses and Dissertations

High fluoride concentrations in drinking water affect millions of people around the world. The World Health Organization recommended a fluoride concentration in drinking water of ≤ 1.5 mg/L; fluoride above this concentration can cause long-term dental and skeletal fluorosis. Fluoride imparts no taste to water; therefore, people do not realize that they are ingesting high fluoridated water. Researchers sought to develop a material to remove fluoride from drinking water through sorption. Aluminum was used to form a double ionic layer on the bentonite clay surface. Once mixed in contaminated water, a coagulant, ferric sulfate, was used to separate the bentonite …

Control Of Corrosion On Ss316l Using Surface Initiated Polymers, Alexander Rupprecht

Electronic Theses and Dissertations

Pitting corrosion is arguably one of the most destructive and dangerous forms of corrosion, resulting in damage to structures, the environment, and public health. In addition, damage caused to structures such as bridges, pipelines, and boats, corrosion also has a profound effect on the biomedical community. Implanted metallic devices (i.e., vascular stents and artificial joints) are prone to pitting corrosion caused by aggressive ions present in extracellular fluid. To provide a corrosion-resistant surface on SS316L, films of poly(styrene), poly(methyl acrylate), and poly(methyl methacrylate) were formed using surface-initiated atom transfer radical polymerization (SI-ATRP). The resulting hydrophobic polymer films had a fractional …

From The Lafitte Greenway To The Carondelet Canal: Genealogy Of An Emerging Place On The New Orleans Landscape, Elizabeth Williams

LSU New Orleans Theses and Dissertations

In 2015, New Orleans opened the Lafitte Greenway, a linear urban bike path. The Lafitte Greenway follows the footprint of the Carondelet Canal, a historic shipping channel developed in the late-eighteenth century. While it was created as a public resource, the Carondelet Canal became a thriving residential and commercial corridor during New Orleans’ antebellum period, accompanied by public spaces in which class- and race-based hierarchies were produced, contested, and reimagined. Archaeological and archival data from Square 240, a block along the canal’s route, illustrate the tensions inherent in the production of urban public spaces, both past and present. A genealogy …

Applied Molecular Dynamics: From Targeting Viral Helicases, To Understanding The Interactions Of Cucurbituril Complexes In Ionic Solutions, Bryan Raubenolt

LSU New Orleans Theses and Dissertations

Molecular Dynamics simulations are a highly useful tool in helping understand the fundamental interactions present in a variety of chemical systems. The work discussed here illustrates it’s use in determining the conformational dynamics of the Zika and SARS-Cov-2 helicase in a physiological environment, largely in an effort to discover inhibitors capable of rendering the protein inert. Additionally, we show how it can be used to understand paradoxical trends in the anion-induced precipitation of Cucurbituril cavitands.

Viral helicases are motor proteins tasked with unwinding the viral dsRNA, a crucial step in preparing the strand to be translatable by host cells. By …

Pharmaceuticals And Personal Care Products In Pacific Northwest Coastal Ecosystems: Spatial Variation, Organism Effects, And Consumer Perspectives, Amy Lynne Ehrhart

Dissertations and Theses

Anthropogenic pollution poses a threat to marine organisms and ecosystems worldwide. Common chemical pollutants that enter the marine environment include legacy contaminants, which are well known and heavily regulated or banned pollutants, and emerging contaminants, which are more recently recognized as pollutants and often lack regulatory limits for their use and discharge. Wastewater treatment plant (WWTP) effluent is a major source of various contaminants of concern, particularly pharmaceutical and personal care products (PPCPs) that are not fully removed during treatment. PPCPs exist at low concentrations in the environment and may have unknown and subtle effects on marine life. Data gaps …

Ypfs Lessons Learned Oral History Project: An Interview With Sohail Khan, Sohail Khan, Steven H. Kasoff, Matthew A. Lieber

Documents

Suggested Citation Form: Khan, Sohail, 2020. “Lessons Learned Interview."Interview by Steven H. Kasoff and Matt A. Lieber. Yale Program on Financial Stability Lessons Learned Oral History Project. December 18, 2020. Transcript. https://ypfs.som.yale.edu/library/ypfs-lesson-learned-oral-history-project-interview-sohail-khan

Nanomaterial Composites Based On Potassium Hexaniobate, Perovskites, And Iron Triazole Spin Crossover Complexes, Alexis A. Blanco

LSU New Orleans Theses and Dissertations

Development of novel materials with sought after properties has been the forefront in the field of nanomaterials. Hybrid nanomaterial architectures, or nanocomposites, is an important subgroup within the material chemistry umbrella. One such example of nanocomposite systems is peapod-like structures that are composed of 0D nanoparticles (“peas”) and 2D nanosheets (“pods”). Nanopeapods may display unique properties that were not attainable within individual components. BaTiO₃ nanoparticles can be produced using solvothermal methods (20 h) in the presence of Ba(NO₃)₂, titanium (IV) butoxide, and oleic acid as the surfactant. Synthesis parameters were modified to allow for both …

A Numerical And Experimental Study Of Lid Driven Square Cavity Flow For Laminar And Turbulent Cases, Abdullah Bin Naeem

LSU New Orleans Theses and Dissertations

Experimental and numerical studies are performed on steady and unsteady lid-driven cavity flow for laminar flow regime. In the experiments, a PIV and an LDA were employed to measure the global and local velocities, respectively inside a cavity of AR 1.0. The velocity vector plots and streamline plots which represent unsteady circulation patterns are obtained using the PIV. The steady local velocities measured with LDA are then used to calibrate the PIV measurements. The numerical study is performed using a commercial CFD solver. For turbulent flow simulation RANS equations with K-Epsilon closure model were used. From the PIV calibration study, …

Multi-Level Small Area Estimation Based On Calibrated Hierarchical Likelihood Approach Through Bias Correction With Applications To Covid-19 Data, Nirosha Rathnayake

Theses & Dissertations

Small area estimation (SAE) has been widely used in a variety of applications to draw estimates in geographic domains represented as a metropolitan area, district, county, or state. The direct estimation methods provide accurate estimates when the sample size of study participants within each area unit is sufficiently large, but it might not always be realistic to have large sample sizes of study participants when considering small geographical regions. Meanwhile, high dimensional socio-ecological data exist at the community level, providing an opportunity for model-based estimation by incorporating rich auxiliary information at the individual and area levels. Thus, it is critical …

Bayesian Modeling For Longitudinal Count Data: Applications In Biomedical Research, Morshed Alam

Theses & Dissertations

Biomedical count data such as the number of seizures for epilepsy patients, number of new tumors at each visit or the number vomiting after each chemo-radiation for the cancer patients are common. Often these counts are measured longitudinally from patients or within clusters in multi-site trials. The Poisson and negative binomial models may not be adequate when data exhibit over or under-dispersion, respectively. On the contrary, a variety of dispersion conditions in count data can be captured by Conway-Maxwell Poisson (CMP) model.

This doctoral dissertation relegates to developing a statistical methodology to model longitudinal count data distributed as CMP via …

Statistical Modeling Of Survival Data Using Frailty Models, Adams Kusi Appiah

Theses & Dissertations

In many clinical trials, time-to-event endpoints are often adopted to demonstrate a clinically convincing effect of treatments appropriately. These variables might be clustered or correlated because of certain common features, such as genetic traits or shared environmental factors or repeated events. Observations from the same cluster are assumed to be correlated because they usually share specific unobserved characteristics. Ignoring the correlations between the survival times may lead to incorrect estimates of parameters of interest and invalid statistical inferences. The scientific interest may lie in the estimation of treatment effect while accounting for the correlated event times. This dissertation proposes a …

Deciphering The Catalytic Mechanism Of Human Manganese Superoxide Dismutase, Jahaun Azadmanesh

Theses & Dissertations

The livelihood of human cells is heavily dependent on the ability to modulate the presence of highly reactive oxygen-based molecules termed reactive oxygen species (ROS). In excess, ROS facilitate oxidative damage to the macromolecules of cellular life. SODs are the major family of antioxidant proteins that prevent the buildup of overwhelming amounts of ROS within cells. Sometimes dubbed the “first line of defense” against oxidative damage, SODs defend against the harmful accumulation of ROS by eliminating superoxide. Superoxide is a ROS itself that is also a precursor to much more harmful ROS molecules. MnSOD is the manganese containing form of …

Machine Learning Model Selection For Predicting Global Bathymetry, Nicholas P. Moran

LSU New Orleans Theses and Dissertations

This work is concerned with the viability of Machine Learning (ML) in training models for predicting global bathymetry, and whether there is a best fit model for predicting that bathymetry. The desired result is an investigation of the ability for ML to be used in future prediction models and to experiment with multiple trained models to determine an optimum selection. Ocean features were aggregated from a set of external studies and placed into two minute spatial grids representing the earth's oceans. A set of regression models, classification models, and a novel classification model were then fit to this data and …

Theatre Arts Integration For Deeper Learning In The English-As-A-Foreign-Language Classroom, Andrew Zutell

LSU New Orleans Theses and Dissertations

This quasi-experimental case study examines the impact of theatre arts integration in an English-as-a foreign language (EFL) course in a competency-based international high school. Aiming to engage students in a process of deeper learning through drama, this study focuses on the domain of speaking and oral communicative competence. Although widely recognized as one of the most important college-and-career-readiness skills, oral communication is often overshadowed by high-stakes testing priorities such as reading and writing. In particular, many Chinese students of English struggle to achieve confident oral fluency despite years of study. This research was designed to investigate whether theatre arts integration …

Taking Up Space: A Phenomenological Study Of The Shared Experiences Of Black Women In Stem Graduate Programs At Predominantly White Institutions, Ebony C. Blackwell

LSU New Orleans Theses and Dissertations

In the U.S., marginalized populations are underrepresented in STEM. Specifically, there is a disparity in the number of Black women attaining STEM graduate degrees and entering the STEM workforce. The purpose of this qualitative, phenomenological study was to examine the essence of the shared experiences of Black women currently enrolled in STEM graduate programs at predominantly White institutions (PWIs), in order to increase retention of Black women through STEM graduate programs and into careers; as well as to use participant’s experiences to expose any barriers they encountered related to their educational pursuits, and examine how they were able to navigate …

Thermo-Fluid Characterizations Of The Powder-Bed Fusion Additive Manufacturing Processes Using Laser And Electron Beam, M Shafiqur Rahman

LSU New Orleans Theses and Dissertations

The powder-bed fusion (PBF) process is a subdivision of Additive Manufacturing (AM) technology where a heat source at a controlled speed selectively fuses regions of a powder-bed material to form three-dimensional (3-D) parts. Two of the most effective PBF processes are selective laser melting (SLM) and electron beam additive manufacturing (EBAM), which can fabricate full-density metallic parts in a layer-by-layer fashion. In this study, thermal behavior and melt-pool dynamics in the PBF process are investigated by developing 3-D multiphysics-based thermo-fluid models for both SLM and EBAM, containing Ti-6Al-4V alloy as a powder-bed material. The laser and electron beams are modeled …

A Transformative Approach To Incorporating Adaptive Courseware: Strategic Implementation, Backward Design And Research-Based Teaching Practices, Tonya A. Buchan, Stanley Kruse, Jennifer Todd, Lee Tyson

Current Issues in Emerging eLearning

In July 2016, Colorado State University (CSU) joined seven other land-grant institutions in the Accelerating Adoption of Adaptive Courseware grant sponsored by the Personalized Learning Consortium (PLC) of the Association of Public and Land-grant Universities (APLU). A primary objective of the grant was to scale the adoption of adaptive courseware in general education courses at each of the grant institutions. CSU targeted high-enrollment, general education courses and took a three-pronged, transformative approach to the integration of adaptive courseware. Specifically, CSU divided the courseware integration into three components: 1) strategic implementation of courseware, 2) backward course design, and 3) incorporation of …

Adaptive Analytics: It’S About Time, Charles Dziuban, Colm Howlin, Patsy Moskal, Tammy Muhs, Connie Johnson, Rachel Griffin, Carissa Hamilton

Current Issues in Emerging eLearning

This article describes a cooperative research partnership among a large public university, a for-profit private institution and their common adaptive learning platform provider. The focus of this work explored adaptive analytics that uses data the investigators describe as metaphorical “digital learning dust” produced by the platform as a matter of course. The information configured itself into acquired knowledge, growth, baseline status and engagement. Two complimentary models evolved. The first, in the public university, captured end-of-course data for predicting success. The second approach, in the private university, formed the basis of a dynamic real-time data analytic algorithm. In both cases the …

Student Perceptions Of The Effectiveness Of Adaptive Courseware For Learning, Patricia O'Sullivan, Christina Forgette, Stephen Monroe, M. Tyler England

Current Issues in Emerging eLearning

Despite the increasing research on the effectiveness of adaptive learning courseware by vendors and academic institutions, there are few published, peer-reviewed studies on adaptive courseware that address the student experience and student perception of this teaching and learning tool. Over the course of two academic years, 2017/2018 and 2018/2019, researchers at the University of Mississippi conducted 16 course-based student focus groups and gathered data from 4 end-of-semester surveys to understand how students are experiencing adaptive courseware and whether or not they find it adds value to their education. Our study found that, although students generally find courseware to be helpful …

Current Issues In Emerging Elearning, Volume 7, Issue 1: Aplu Special Issue On Implementing Adaptive Learning At Scale

Current Issues in Emerging eLearning

The second of two Specials Issues of the CIEE journal to have been produced and guest edited by the Personalized Learning Consortium (PLC) of the Association of Public and Land-grant Universities (APLU), featuring important research resulting from university initiatives to launch, implement and scale up the use of adaptive courseware and the strategies of adaptive learning.