Digital Commons Network^™

Machine Girl, Yutong Liu

Theses and Dissertations

Machine girl is a character that mimics biology, labor, and humanity.

She relates to machine sympathy and machine learning; She is updating and processing of big data. During the interaction between me and the machine, I found you --- Machine girl.

Machine girl is a brilliant girl. She is an excellent translator and communicator, which is determined by her ability for machine learning. The cyber living space gives her a fundamental learning gift with a mathematical algorithm. She uses this gift to mimic everything from the human brain. She is not reasonable but sensitive. There are many different versions of …

Reaction Profiling Of Extracellular Protein Phosphorylation Through A Microfluidic Reactor Coupled With Raman Spectroscopy, Abigail Casey

Theses and Dissertations

Diseases and disorders in the human body are considered abnormalities of proper cellular function. Understanding the signal transduction mechanisms that cause these abnormalities is crucial to developing earlier detection methods, better treatment options and effective cures. While current diagnostic procedures are powerful tools in diagnosing diseases, they are ineffective in informing physicians on the real-time behavior of the signal transduction mechanisms associated with diseases and disorders. Currently, disease progression is monitored over time through routine patient visits and testing by one or more of the above techniques. By developing an approach that can monitor structural and conformational changes of proteins …

Metal-Oxide Nanostructures Fabricated From Reactive Laser Ablation In Liquid, Mallory G. John

Theses and Dissertations

The development of metal-oxide nanostructures is a growing area due to their applications in diverse fields spanning energy conversion and storage, chemical manufacturing, and en- vironmental technology. This interest in catalytically active nanomaterials has prompted the synthesis and investigation of highly functionalized nanoparticles (NPs), including core- shell, silicate-stabilized, and bi- and multi-metallic nanocomposites. While wet-chemical synthesis methods of metal-oxide nanostructures have led to several morphologies, compositions, and shapes, these syntheses often require high temperatures, toxic solvents or reducing agents, and long reaction times.

Laser synthesis and processing of colloids (LSPC) encompasses both ‘top down’ and ‘bottom up’ approaches to synthesize …

Parakupa Vena - Fall From The Highest Point, Mariana Parisca Englert

Theses and Dissertations

This document is a collection of the ideas and research that drive my artistic practice. My research focuses on investigating the power structures, historical roots, and existential implications of the current Venezuelan economic crisis, one of the most drastic economic collapses of modern times. The ideological rifts created in the Cold War era created a deep anti-socialist sentiment that inhibits our ability to responsibly acknowledge global interdependence. I visualize collective belief systems that gain power from their proposed neutrality. I point to the existence of value beyond the parameters and measures of global capitalism that encourage dependence. I see the …

Investigation Into The Reaction Profile Of A Bioinspired Nickel Complex, Denver Heitger

Theses and Dissertations

Metal complexes that can activate natural oxidants like H₂O₂ and O₂ have become a key research topic in many labs in hope of mimicking nature, by generating a bioinspired complex that can perform unique chemistry through green processes. To prepare the perfect catalyst, this has lead scientists to explore numerous avenues, including the use of both natural and artificial oxidants, to tease apart the reaction pathway taking place. A ligand system dear to the Lucas Lab (13-DOB) has been metalated with nickel, a cheap and earth abundant transition metal. Our bioinspired metal-(di)oxygen adducts can be formed …

Comparing Coastal Storm Impact To Decadal Change In Barrier Island Ecosystems, Philip A. Tuley

Theses and Dissertations

Highly dynamic coastal systems respond to disturbance events with a combination of topographic and vegetative changes. Sea level rise impacts on barrier islands have been quantified, but storm effects on vegetation are limited. Here we quantified barrier island vegetation change in response to an isolated storm event and compared to long-term periods. We hypothesized that disturbance-resisting areas with high woody vegetation cover and/or high foredune elevation would experience minimal transitions after a storm event, whereas disturbance-reinforcing areas with low vegetation cover and low foredune elevation would experience greater transitions between ecosystem states after a storm event. Patterns of dissonance were …

Why We Use A New Currency: The Role Of Trust And Control In Explaining The Perception And Usage Of Bitcoin, Joseph B. Walton

Theses and Dissertations

Social media, e-commerce, global peer-to-peer technologies, and the near ubiquity of computers and smartphones allow people to interact, trust, and exchange value across traditional socio-economic control boundaries and over significant distances. Since the creation in 2008 of a new cryptographic currency system called Bitcoin, a financial technology market sector of about 250 billion USD has rapidly emerged, raising questions about the nature of currency in society and whether new types of non-national money are warranted and viable. This debate has pitted heterodox economic interests against orthodox economic interests while it has rekindled interest in theories that view money as a …

Probing Vibrational Wave Packets In Organophoshorous Molecules Using Femtosecond Time-Resolved Mass Spectrometry (Ftrms), Derrick Ampadu Boateng

Theses and Dissertations

The study of organophosphorus and nitroaromatic compounds is essential due to their suitability as models for understanding the dynamics of radiation induce damage to DNA sugar-phosphate backbone, and the detection of chemical warfare agents as well as nitroaromatic explosives (such as TNT). The ultrafast dynamics of these polyatomic radicals were studied using femtosecond time-resolved mass spectrometry (FTRMS), a versatile method that is capable of monitoring the ultrafast dynamics of rapid dissociation in the gas phase after the removal of an electron. The method uses a technique called pump-probe, which makes use of two time-delayed laser pulses. In this work, the …

Invariance And Invertibility In Deep Neural Networks, Han Zhang

Theses and Dissertations

Machine learning is concerned with computer systems that learn from data instead of being explicitly programmed to solve a particular task. One of the main approaches behind recent advances in machine learning involves neural networks with a large number of layers, often referred to as deep learning. In this dissertation, we study how to equip deep neural networks with two useful properties: invariance and invertibility. The first part of our work is focused on constructing neural networks that are invariant to certain transformations in the input, that is, some outputs of the network stay the same even if the input …

Novel Bayesian Techniques For Dose Response Data, Faten Alamri

Theses and Dissertations

All forms of life are being exposed to different levels of harmful chemicals that can cause various and serious side effects. Toxicological experiments enable researchers to test these chemicals on animal to determine their major effects. Although optimal and acceptable dose levels have been investigated, researchers continue to strive to minimize side effects and the chemical dosages. Dose-response models and other benchmark approaches play a role in determining the acceptable exposure levels of hazardous chemicals. Parametric techniques, used to determine the tolerable dosages, utilizing ANOVA and non-linear regression models are well represented in the literature. We determined the benchmark dose …

Towards A Greener Route To Blockbuster Statin Drugs: Harnessing The Power Of Biocatalysis And Integrating Cross-Coupling Catalysis In The Synthesis Of Rosuvastatin, Chanaka M. Amarasekarage

Theses and Dissertations

As global and political awareness about green and sustainable practices sharpens in the face of dramatic climate change and environmentally detrimental practices, one attractive approach is to harness the catalytic potential of enzymes. Thus influenced, our efforts focused on the development of an innovative chemoenzymatic route to widely prescribed Blockbuster statin drugs, specifically rosuvastatin. In this work, we engineered novel deoxyribose phosphate aldolase (DERA) variants via rationally designed site-directed mutagenesis to accept non-natural, less polar substrate, acrolein, along with acetaldehyde. Several of new mutants displayed elevated tolerance towards aldehydes and showed effective incorporation of acrolein into the unprecedented enzymatically-derived chiral …

Optical Spectroscopy And Theoretical Modelling Of Carrier Dynamics In Group-Iv Alloy Quantum Dots, Rahnuma Rahman

Theses and Dissertations

In recent years, Ge_1−xSn_x alloy quantum dots (QDs) have attracted significant interest due to their potential applications in photodetectors and light emitting devices in visible to mid IR spectral range and compatibility with silicon based platforms. While bulk Ge is an indirect bandgap semiconductor (0.66 eV), direct transitions can be made possible by incorporation of α-Sn at concentrations of ~10%, which however lowers the bandgap. Utilizing quantum confinement by reducing the size to below the Bohr radius also promotes direct transitions and more importantly increases the fundamental transition energies in GeSn alloy QDs, making them suitable for …

Sound Propagation In Viscous Flows Using Piezoelectric Sensors And Non-Destructive Propagation Techniques And Its Applications, Ahmed M. Abdulkareem

Theses and Dissertations

Structural non-destructive evaluation techniques are applied to viscous flows to detect fluid property changes. The main operating principle consists of an actuator which provides a stimulus, and a sensor to receive a signal traveling to a fluid domain. The main challenge of the operating principle consists of investigating waves traveling in a viscous flow. Traveling waves utilizing a piezoelectric actuator-sensor pair are modeled and the results are validated experimentally. ANSYS models, coupled with a two-way fluid-solid interaction model, are built to investigate how far a signal travels and what frequency ranges are of interest. The numerical model includes modeling three …

Estimating Response Status In Sequential Multiple Assignment (Smar)-Like Trials, Keighly Bradbrook

Theses and Dissertations

Sequential, multiple assignment, randomized trials (SMARTs) allow investigators to develop and compare experimental treatment regimens in which individuals are successively randomized to different treatments based on some set of predetermined rules. The rules used to make decisions on when and how to switch treatments are based on a chosen set of tailoring variables. Although not always true, intermediate response is commonly used as the primary tailoring variable as it is often predictive of future treatment success. As such, successful implementation depends on identifying patients who respond to treatment, though in some situations such mechanisms may not exist. Further, patient-level covariates …

Data Science Methods For Standardization, Safety, And Quality Assurance In Radiation Oncology, Khajamoinuddin Syed

Theses and Dissertations

Radiation oncology is the field of medicine that deals with treating cancer patients through ionizing radiation. The clinical modality or technique used to treat the cancer patients in the radiation oncology domain is referred to as radiation therapy. Radiation therapy aims to deliver precisely measured dose irradiation to a defined tumor volume (target) with as minimal damage as possible to surrounding healthy tissue (organs-at-risk), resulting in eradication of the tumor, high quality of life, and prolongation of survival. A typical radiotherapy process requires the use of different clinical systems at various stages of the workflow. The data generated in these …

Verification Of The Vertical Bubble Flow Experiments, Reginald Jones Ii

Theses and Dissertations

Detailed experimental design to support basic pedagogy of flow regimes – single phase liquid, bubbly, slug, annular, dispersed droplet, and single phase vapor – occurring in flow channels of nuclear reactors has been developed for EGMN 203 - Nuclear Engineering Practicum offering at Virginia Commonwealth University’s Department of Mechanical and Nuclear Engineering. The laboratory instruction will be used to help students forming ideas and understanding flow regimes occurring in nuclear engineering applications. We designed and constructed four water columns to act as surrogates for water channels in a nuclear reactor. Each column was used for a different experiment: salted versus …

Multi-Label Classification Models For Heterogeneous Data: An Ensemble-Based Approach., Jose Maria Moyano Murillo

Theses and Dissertations

In recent years, the multi-label classification gained attention of the scientific community given its ability to solve real-world problems where each instance of the dataset may be associated with several class labels simultaneously, such as multimedia categorization or medical problems.

The first objective of this dissertation is to perform a thorough review of the state-of-the-art ensembles of multi-label classifiers (EMLCs). Its aim is twofold: 1) study state-of-the-art ensembles of multi-label classifiers and categorize them proposing a novel taxonomy; and 2) perform an experimental study to give some tips and guidelines to select the method that perform the best according to …

The Analysis Of Neural Heterogeneity Through Mathematical And Statistical Methods, Kyle Wendling

Theses and Dissertations

Diversity of intrinsic neural attributes and network connections is known to exist in many areas of the brain and is thought to significantly affect neural coding. Recent theoretical and experimental work has argued that in uncoupled networks, coding is most accurate at intermediate levels of heterogeneity. I explore this phenomenon through two distinct approaches: a theoretical mathematical modeling approach and a data-driven statistical modeling approach.

Through the mathematical approach, I examine firing rate heterogeneity in a feedforward network of stochastic neural oscillators utilizing a high-dimensional model. The firing rate heterogeneity stems from two sources: intrinsic (different individual cells) and network …

Investigations Of Graphene-Supported Single-Atom Catalyst Model Ions In The Gas Phase, Michael Borrome

Theses and Dissertations

Recent developments in heterogeneous catalysis has led to the conception of single-atom catalysts (SACs), a class of catalysts based on isolated metal atoms anchored to a support scaffold. SACs are often much more reactive and can offer better selectivity when compared to nano-scale catalysts. In order to realize the full potential of SACs, a sound understanding of the underlying catalytic mechanisms is required. However, surface analysis tools can become less effective in studying catalytic mechanisms at the atomic scale. Mass spectrometry has proven to be a robust technique for studying organometallic catalytic mechanisms at the single-molecule level. Using mass spectrometry, …

Separate And Unequal: Latinx Access, Enrollment And Completion Of Ap Coursework In The State Of Virginia, Virginia Elizabeth Palencia

Theses and Dissertations

In response to the national problem of overrepresentation of Latinx students in general education classes, this study addresses Latinx access to Advanced Placement (AP) coursework, enrollment, and completion patterns in Virginia, a growing destination state for many Latinx families and students. Through a secondary data analysis of both the Civil Rights Data Collection (2015-6) and College Board data (2016), this quantitative study mapped patterns of disproportionality in AP access, enrollment, and completion for Latinx students, who comprise 13% of enrollment in Virginia public high schools. In addition, a case study of two diverse school districts provides evidence of segregation and …

Sparsity And Weak Supervision In Quantum Machine Learning, Seyran Saeedi

Theses and Dissertations

Quantum computing is an interdisciplinary field at the intersection of computer science, mathematics, and physics that studies information processing tasks on a quantum computer. A quantum computer is a device whose operations are governed by the laws of quantum mechanics. As building quantum computers is nearing the era of commercialization and quantum supremacy, it is essential to think of potential applications that we might benefit from. Among many applications of quantum computation, one of the emerging fields is quantum machine learning. We focus on predictive models for binary classification and variants of Support Vector Machines that we expect to be …

The Role Of Receptive Reasoning In The Development Of Intellectual Humility, Cathryn Richmond

Theses and Dissertations

Intellectual humility (IH) develops throughout childhood and adolescence and is critically important for effective learning, particularly with regard to science; however, the research examining the development of IH in children is quite limited. As such, this study utilized an exploratory, mixed methods, community-engaged research design with children ages three to 10 (n = 60; M_age = 5.98; 69.6% female) and their parents/guardians recruited from a public children’s museum.. As the construct of IH is intended to describe adult cognition, I operationalized the set of components that may lead to the development of IH in preschool children as Receptive …

Interpersonal Competency Configurations And The School Adjustment Of Early Adolescents With Disabilities: A Person-Centered Approach, Brittany I. Sterrett

Theses and Dissertations

The transition to middle school is a critical time in adolescence. The more complex school environment provides opportunities for growth and challenges for students with disabilities. Although special education strives to provide individualized supports to students with disabilities through data-based decision-making, the tools used to understand and meet the needs of these students are often unresponsive to the dynamic nature of development and student adjustment as they age. Grounded in developmental science, this study sought to create a data collection framework through a person-centered approach to inform the individualization process. Specifically, this study: 1) explored a decision process that allows …

Community Development Financial Institutions (Cdfis): An Analysis Within The Political And Economic Context Of Neoliberalism, Tracie Victoria Wynand

Cal Poly Humboldt theses and projects

This thesis explores Community Development Financial Institutions (CDFIs) business models by examining the organizational structures, procedural operations, services, and geography. It aims to understand its overall behavior as a financial institution providing low-income communities financial services and ultimately the role it plays within the neoliberal context. The research identifies that CDFIs ultimately hold a mission that promotes economic prosperity from within the neoliberal project by expanding free-market capitalist beliefs and practices when servicing low-income communities. Additionally, the findings suggest that CDFIs take on the role of the neoliberal state by operating in tandem with the Nonprofit Industrial Complex (NPIC), which …

Changes In Prey Mortality: The Efects Of Multiple Predators And Temperature On California Mussels, Wesley Hull

Cal Poly Humboldt theses and projects

Organisms serve as prey to a variety of predators within natural systems, detecting threats through physical and chemical means. While predator feeding behavior is also affected by the presence of other predators, it is unclear whether differing modes of detection have similar effects on predator feeding behavior. In rocky intertidal zones in northern California, the California mussel (Mytilus californianus) is a competitively dominant foundation species consumed by a variety of predators. I quantified the individual and combined effects of ochre star (Pisaster ochraceus) and rock crab (Romaleon antennarium) predation on mussels by implementing mussel …

Coho Salmon (Oncorhynchus Kisutch) Dispersal And Life History Variations Among Humboldt Bay Watersheds, Madison J. Halloran

Cal Poly Humboldt theses and projects

The decline of Coho Salmon (Oncorhynchus kisutch) in California is the result of various anthropogenic effects across the landscape, affecting all stages of their anadromous life history. Monitoring a subset of the remaining populations is essential to evaluate the success of management actions and develop new restoration projects. Defining the appropriate spatial scale for this monitoring and restoration depends on the frequency and extent of dispersal of individuals across watershed boundaries. Coho Salmon life-cycle monitoring projects in California estimate the abundance of juveniles and adults over time in selected focal watersheds. If individuals frequently enter or leave the …

The Effects Of Feral Cat Removal On Rat Abundance In An Insular, Tropical Ecosystem, Douglas A. Page

Cal Poly Humboldt theses and projects

The colonization by rats (Rattus spp.) and cats (Felis catus) on islands are known to contribute to the decline of native birds. On the island of Rota, Commonwealth of the Northern Mariana Islands, cats are being lethally removed to conserve two endangered bird species. Although cats are controlled to reduce impacts on birds, they can also prey heavily on sympatric rats. Of euthanized feral cats on Rota, 60% had ≥1 rat in the stomach. Predation by cats could be a mechanism of top-down control of rats. Removing feral cats may reduce the magnitude of that control, leading …

Sediment Production And Delivery From Timber Harvest Roads In Humboldt County, California, Chris P. Faubion

Cal Poly Humboldt theses and projects

Sediment delivery from unpaved actively-used and relatively un-trafficked forest roads are one of the most common sources of impairment to aquatic ecosystems. Hence the objectives of this study were to: 1) compare the variability in erosion rates from actively used and relatively un-trafficked timber harvest roads across multiple water years in Railroad Gulch; 2) identify segment scale controls on road surface erosion and road-to-stream connectivity; 3) develop storm-based and annual segment scale models to predict road sediment production and compare the accuracy of these models to WEPP: Road; and 4) estimate road-related sediment loads to streams.

Between 2014 and 2019 …

Comparisons Of Spatial Reasoning Abilities Of String And Non-String Professional Musicians, Baby Vivian L. Esenbock

Cal Poly Humboldt theses and projects

This study provides evidence to support the transferable benefits of musical training to enhance performance on cognitive tasks involving spatial reasoning abilities. Spatial reasoning is an important skill that is essential for success in science, technology, engineering, and mathematics (STEM) achievement. Previous research indicates that students involved with musical instrument training score higher on measures of spatial temporal abilities than students with no musical training. We hypothesized that the greatest development of spatial visualization will be found in string instrument musicians when compared to non-string musicians, because of the visualization required due to the design of these instruments. Two studies …

Shifting Sands: Social Cues Influence The Long-Term Dynamics Of Snowy Plover Distribution, Jeremy John Pohlman Mr

Cal Poly Humboldt theses and projects

Understanding the social and physical factors that influence the temporal and spatial distribution of a species is imperative for successful management. The Western Snowy Plover (Charadrius nivosus nivosus) selects for wide-open stretches of beach; yet within large expanses of ideal habitat, plover populations tend to be aggregated. Recent evidence suggests plovers may prioritize social information over ideal physical factors alone when selecting breeding locations. I analyzed data collected on an individually marked population of Snowy Plovers in Humboldt County, California from 2001 to 2018 to evaluate the influence of physical (beach width) and social (presence of conspecifics) landscape …