A Luminescence-Based System For Identification Of Genetically Encodable Inhibitors Of Protein Aggregation, Travis J. Nelson, Shuo Liang, Cliff I. Stains

Department of Chemistry: Faculty Publications

Molecules that disrupt protein aggregation represent potential tool compounds for the investigation of numerous human disease states. However, the identification of small molecules capable of disrupting protein aggregation has proven challenging. Larger biomolecules such as antibodies and proteins are promising alternatives due to their increased size. Despite the promise of protein-based inhibitors, generalizable assays are needed to more readily identify proteins capable of inhibiting aggregation. Herein, we utilize our previously reported self- assembling NanoLuc luciferase fragments to engineer a platform in which both detection reagents are expressed from the same plasmid, enabling facile co-transformation with a genetically encodable inhibitor. This …

Domain Wall Conduction In Calcium-Modified Lead Titanate For Polarization Tunable Photovoltaic Devices, Chong-Xin Qian, Hong-Jian Hong-Jian, Qiang Zhang, Jiawei He, Zi-Xuan Chen, Ming-Zi Wang, Xiao Cheng Zeng

Department of Chemistry: Faculty Publications

Ferroelectric domain wall (DW) conduction, confirmed in recent experiments, has attracted intense attention due to its promising applications in optoelec- tronic devices. Herein, we provide theoretical evidence of electric conduction in Pb0.8Ca0.2TiO3 (PCT) DWs. The separation of charge accumulation in DWs, corresponding to the electronic conduction-band minimum (CBM) and valence-band maximum (VBM), weakens the tendency for the electron-hole recombination, thereby providing more efficient channels for charge transfer. We fabricate PCT-based functional photovoltaic devices with polarization tunable charge transfer to exploit the combined conduction and ferroelectric properties of the DW. The photovoltaic performance of the devices can be regu- lated by …

The Fluxnet2015 Dataset And The Oneflux Processing Pipeline For Eddy Covariance Data, Gilberto Pastorello, Timothy Arkebauer, Dave P. Billesbach, Anatoly Gitelson, Adam Liska, Andrew Suyker, Elizabeth Walter-Shea, More Than 200 Other

Adam Liska Papers

The FLUXNET2015 dataset provides ecosystem-scale data on CO2, water, and energy exchange between the biosphere and the atmosphere, and other meteorological and biological measurements, from 212 sites around the globe (over 1500 site-years, up to and including year 2014). These sites, independently managed and operated, voluntarily contributed their data to create global datasets. Data were quality controlled and processed using uniform methods, to improve consistency and intercomparability across sites. The dataset is already being used in a number of applications, including ecophysiology studies, remote sensing studies, and development of ecosystem and Earth system models. FLUXNET2015 includes derived-data products, such as …

Adhd Parent And Teacher Symptom Ratings: Differential Item Functioning Across Gender, Age, Race, And Ethnicity, George J. Dupaul, Qiong Fu, Arthur D. Anastopoulos, Robert C. Reid, Thomas J. Power

Department of Special Education and Communication Disorders: Faculty Publications

Parent and teacher ratings of the two attention-deficit/hyperactivity disorder (ADHD) symptom dimensions (i.e., inattention, hyperactivity-impulsivity) have been found to differ across child gender, age, race, and ethnicity. Group differences could be due to actual variation in symptomatic behaviors but also could be due to measurement items functioning differently based on child characteristics. This study extended prior investigations establishing measurement invariance at the symptom dimension and item levels, by examining possible measurement variance across child demographic characteristics at the item level (i.e., differential item functioning [DIF]) in two large national samples. Using the Rasch rating scale model (Andrich Psychometrika, 43, …

Acoustic Space Occupancy: Combining Ecoacoustics And Lidar To Model Biodiversity Variation And Detection Bias Across Heterogeneous Landscapes, Danielle I. Rappaport, J. Andrew Royle, Douglas C. Morton

United States Geological Survey: Staff Publications

There is global interest in quantifying changing biodiversity in human-modified landscapes. Ecoacoustics may offer a promising pathway for supporting multi-taxa monitoring, but its scalability has been hampered by the sonic complexity of biodiverse ecosystems and the imperfect detectability of animal-generated sounds. The acoustic signature of a habitat, or soundscape, contains information about multiple taxa and may circumvent species identification, but robust statistical technology for characterizing community-level attributes is lacking. Here, we present the Acoustic Space Occupancy Model, a flexible hierarchical framework designed to account for detection artifacts from acoustic surveys in order to model biologically relevant variation in acoustic space …

Human-Associated Species Dominate Passerine Communities Across The United States, Helen R. Sofaer, Curtis H. Flather, Catherine S. Jarnevich, Kristin P. Davis

United States Geological Survey: Staff Publications

Aim: Human development and agriculture can have transformative and homogenizing effects on natural systems, shifting the composition of ecological communities towards non-native and native species that tolerate or thrive under human-dominated conditions. These impacts cannot be fully captured by summarizing species presence, as they include dramatic changes to patterns of species abundance. However, how human land use patterns and species invasions intersect to shape patterns of abundance and dominance within ecological communities is poorly understood even in well-known taxa.

Location: Conterminous United States.

Time period: 2010–2012.

Major taxa studied: Passeriformes.

Methods: We analyse continental-scale monitoring data to study the proportional …

Admissions Viewbook, 2020-2021, Illinois State University, Office Of Admissions

Admissions Viewbook

Recruitment booklet created by Illinois State University's Office of Admissions

Signal Passing Self-Assembly Simulates Tile Automata, Angel A. Cantu, Austin Luchsinger, Robert Schweller, Tim Wylie

Computer Science Faculty Publications

The natural process of self-assembly has been studied through various abstract models due to the abundant applications that benefit from self-assembly. Many of these different models emerged in an effort to capture and understand the fundamental properties of different physical systems and the mechanisms by which assembly may occur. A newly proposed model, known as Tile Automata, offers an abstract toolkit to analyze and compare the algorithmic properties of different self-assembly systems. In this paper, we show that for every Tile Automata system, there exists a Signal-passing Tile Assembly system that can simulate it. Finally, we connect our result with …

Revision Of The Eocene 'Platyrhina' Species From The Bolca Lagerstätte (Italy) Reveals The First Panray (Batomorphii: Zanobatidae) In The Fossil Record, Giuseppe Marramà, Giorgio Carnevale, Kerin M. Claeson, Gavin J P Naylor, Jürgen Kriwet

PCOM Scholarly Works

The fossil-Lagerstätte of Bolca (Italy) is well known for the diversity and exquisite preservation of its bony and cartilaginous fishes documenting tropical shallow-water marine environments associated with coral reefs in the western Tethys during the early Eocene. In this study, the taxonomic, systematic and phylogenetic position of two batoid species traditionally assigned to the living thornback ray genus Platyrhina is re-evaluated. †Platyrhina bolcensis Heckel, 1851 is recognized as a separate species of the Platyrhinidae because of its plate-like antorbital cartilage with an irregular outline and a small horn on the nasal capsules. Also, the rostral cartilage does not reach …

Molecular Social Reality, The Cultural Helix & Sequencing Social Dna, Aidan Christopher Haughey

University Honors Theses

This thesis provides a theory for measuring Social Reality, along with a framework and model which apply that theory to measure presented social reality in media. The framework and model utilize the double helical structure of DNA to create a baseline unit of social reality that can be extracted from media to help measure and categorize social realities. An experiment is provided utilizing a custom built machine learning algorithm to demonstrate the practical application of the theory, framework, and model.

Standardized Short-Term Acute Heat Stress Assays Resolve Historical Differences In Coral Thermotolerance Across Microhabitat Reef Sites, Christian R. Voolstra, Carol Buitrago-López, Gabriela Perna, Anny Cárdenas, Benjamin C. C. Hume, Nils Rädecker, Daniel J. Barshis

Biological Sciences Faculty Publications

Coral bleaching is one of the main drivers of reef degradation. Most corals bleach and suffer mortality at just 1–2°C above their maximum monthly mean temperatures, but some species and genotypes resist or recover better than others. Here, we conducted a series of 18‐hr short‐term acute heat stress assays side‐by‐side with a 21‐day long‐term heat stress experiment to assess the ability of both approaches to resolve coral thermotolerance differences reflective of in situ reef temperature thresholds. Using a suite of physiological parameters (photosynthetic efficiency, coral whitening, chlorophyll a , host protein, algal symbiont counts, and algal type association), we assessed …

Squids Use Multiple Escape Jet Patterns Throughout Ontogeny, Carly A. York, Ian K. Bartol, Paul S. Krueger, Joseph T. Thompson

Biological Sciences Faculty Publications

Throughout their lives, squids are both predators and prey for a multitude of animals, many of which are at the top of ocean food webs, making them an integral component of the trophic structure of marine ecosystems. The escape jet, which is produced by the rapid expulsion of water from the mantle cavity through a funnel, is central to a cephalopod's ability to avoid predation throughout its life. Although squid undergo morphological and behavioral changes and experience remarkably different Reynolds number regimes throughout their development, little is known about the dynamics and propulsive efficiency of escape jets throughout ontogeny. We …

Mac Protocols For Terahertz Communication: A Comprehensive Survey, Saim Ghafoor, Noureddine Boujnah, Mubashir Husain Rehmani, Alan Davy

Publications

Terahertz communication is emerging as a future technology to support Terabits per second link with highlighting features as high throughput and negligible latency. However, the unique features of the Terahertz band such as high path loss, scattering, and reflection pose new challenges and results in short communication distance. The antenna directionality, in turn, is required to enhance the communication distance and to overcome the high path loss. However, these features in combine negate the use of traditional medium access protocols (MAC). Therefore, novel MAC protocol designs are required to fully exploit their potential benefits including efficient channel access, control message …

Li Zehou: Synthesizing Kongzi, Marx, And Kant, Andrew Lambert

Publications and Research

To understand the details of Li Zehou’s work, it is helpful to first locate it within the social and historical contexts to which Li was responding. Specifically, his work can be understood as a contribution to the struggle to establish the intellectual foundations of a Chinese modernity. As China transitioned away from the long-lived dynastic system that had ended early in the twentieth century, there was intense debate in China about what forms of social and political order should take its place. Marxism emerged as the governing ideology after the Communist revolution, but this did not settle the outstanding social …

Civil Engineering Research In Ireland 2020: Conference Proceedings, Kieran Ruane, Vesna Jaksic, Bidisha Ghosh, Magdalena Hajdukiewicz, Ciaran Hanley, Niall Holmes, Jennifer Keenahan, Zili Li, Patrick Mcgetrick, Ted Mckenna, Mary Moloney, Vikram Pakrashi, Niamh Power

Publications

Civil Engineering Research in Ireland 2020: Conference Proceedings.

Introducing Parallelism To First-Year Cs Majors, Barbara M. Anthony, D. Cenk Erdil, Olga Glebova, Robert Montante

School of Computer Science & Engineering Faculty Publications

We propose to strengthen the computer science (CS) curriculum by embedding parallel concepts in a required first-semester seminar taken by all incoming declared CS majors. We introduce students to parallel computing concepts through a series of unplugged activities so that students see parallel approaches as a natural form of solution to a task. We describe a pilot offering of the class and activities, with measurements and analysis of what students self-report and their performance on assessments.

Leading Through Change: 2020, Domenick Pinto

School of Computer Science & Engineering Faculty Publications

Having served as department chair and school director for 31 years, I have witnessed a tremendous evolution in the role of chair as economic, social and student climates have changed. My session will summarize collected data from chairs of departments of various sizes and types in order to discuss and understand better our ever changing role as we see responsibilities of delegating, leading change, creative budgeting and fundraising, grant writing and managing conflict become vital to our positions.

Annual Higher Ground Women's Leadership Conference 2020, The Grace E. Harris Leadership Institute At Virginia Commonwealth University

GEHLI - 2026 VCUL Team Project Publications

No abstract provided.

Editorial, Michael E. Whitman, Herbert J. Mattord, Hossain Shahriar

Journal of Cybersecurity Education, Research and Practice

No abstract provided.

Gdom: Granulometry For The Detection Of Obfuscated Malware, John A. Aruta, N. Paul Schembari

Journal of Cybersecurity Education, Research and Practice

We describe the results of a master's thesis in malware detection and discuss the connection to the learning goals of the project. As part of the thesis, we studied obfuscation of malware, conversion of files into images, image processing, and machine learning, a process of benefit to both the student and faculty.

Malware detection becomes significantly more difficult when the malicious specimen is obfuscated or transformed in an attempt to avoid detection. However, computer files have been shown to exhibit evidence of structure when converted into images, so with image processing filters such as granulometry, it is possible to generate …

Storm Tide Amplification And Habitat Changes Due To Urbanization Of A Lagoonal Estuary, Philip Orton, Eric W. Sanderson, Stefan Talke, Mario Giampieri, Kytt Macmanus

Civil and Environmental Engineering Faculty Publications and Presentations

In recent centuries, human activities have greatly modified the geomorphology of coastal regions. However, studies of historical and possible future changes in coastal flood extremes typically ignore the influence of geomorphic change. Here, we quantify the influence of 20th-century man-made changes to Jamaica Bay, New York City, on present-day storm tides. We develop and validate a hydrodynamic model for the 1870s based on detailed maps of bathymetry, seabed characteristics, topography, and tide observations for use alongside a present-day model. Predominantly through dredging, landfill, and inlet stabilization, the average water depth of the bay increased from 1.7 to 4.5 m, tidal …

A Case Study Of Drone Delivery Reliability For Time-Sensitive Medical Supplies With Stochastic Demand And Meteorological Conditions, Travis B. Glick, Miguel Figliozzi, Avinash Unnikrishnan

Civil and Environmental Engineering Faculty Publications and Presentations

Drones are increasingly being utilized to deliver medical supplies, and the COVID-19 pandemic has accelerated this trend. Drones arrive quickly by taking more direct paths and avoiding ground-based obstructions. However, drones are not completely reliable and may also experience failures and delays. For consumer products, delivery delays are an inconvenience, but for some medical supplies, delays may be fatal. This research focuses on the drone reliability of one particular type of supply and event: automatic defibrillators for out-of-hospital cardiac arrests (OHCA). A modeling framework is developed to analyze drone delivery reliability with stochastic demands and meteorological conditions. Using probability distributions …

Synthesis And Design Of Novel Polymer Grafted Nanoparticles Relevant To Drug Delivery Vehicles For Biomedical Application, Maan Abduldiyem Hassan Al-Ali

Theses and Dissertations

The modification of inorganic nanoparticles with organic polymer chains has become a significant field of study for the engineering of advanced nanocomposite materials. This dissertation presents the design, synthesis, and characterization of novel polymer grafted silica nanoparticles as new strategies to combat bacterial resistance. Described herein is the synthesis of monomers that have been graft polymerized onto silica nanoparticles that can be used as a delivery drug vehicle for biomedical applications. The polymerization of these monomers was performed via reversible addition-fragmentation chain transfer (RAFT) polymerization. The molecular design of the RAFT agents that are attached to the surfaces of the …

Facilitating Collaborative Group Work Among Middle School Students Through Digital Game-Based Learning: An Action Research Study To Improve Classroom Instruction, David William Hooks

Theses and Dissertations

This qualitative action research dissertation was an endeavor to strengthen the practitioner-researcher’s ability to foster collaboration skills among eighth grade students in his elective science, technology, engineering, and mathematics (STEM) class. The research question that anchored this study was: To what extent can I foster effective collaboration among my middle school students through the use of an instructional planning framework for collaboration and the strategies associated with digital game-based learning The practitioner-researcher implemented an intervention that utilized a collaborative learning framework while student groups worked together during a digital game-based learning opportunity. The synthesis of a collaboration framework, the elements …

A Gis-Based Risk Assessment For Fire Departments: Case Study Of Richland County, Sc, Tracy Whelen

Theses and Dissertations

Risk assessments enable fire departments to be better prepared for future incidents and to engage in more effective prevention activities. A combination of physical, demographic, and behavioral risk factors combined form a community’s level of risk. This research shows how spatial and nonspatial statistical methods can be used within a GIS framework to create such a risk assessment, with the Columbia-Richland Fire Department in Richland County, SC being used as a case study. Hot spot analysis and thematic mapping of incident rates were used to assess the first research question – what is the spatial variability of structure fires, carbon …

A Mixed Public-Private Partnership Approach For Cyber Resilience Of Space Technologies, Bilge Karabacak, Gokhan Ikitemur, Andy Igonor

All Faculty and Staff Scholarship

Governments today emphasize space systems as critical infrastructures. Many vital services, including communications, transportation, and maritime operations, depend on space systems. Cyber systems represent an essential component that enables effective functioning, configuration, and monitoring of technological space services. Space systems possess unique vulnerabilities and properties that attract the attention of hackers, and often with varying motivations. The private sector increasingly participates in the production of space technologies, and as a result of the differences in perceptions and priorities of governments and the private sector, handling the challenges of governance as it relates to the cybersecurity of space systems presents an …

Human Path Prediction Using Auto Encoder Lstms And Single Temporal Encoders, Hayden Hudgins

Master's Theses

Due to automation, the world is changing at a rapid pace. Autonomous agents have become more common over the last several years and, as a result, have created a need for improved software to back them up. The most important aspect of this greater software is path prediction, as robots need to be able to decide where to move in the future. In order to accomplish this, a robot must know how to avoid humans, putting frame prediction at the core of many modern day solutions. A popular way to solve this complex problem of frame prediction is Auto Encoder …

Lift Ev’Ry Voice: Using Q Methodology To Understand The Shared Perspectives Of African American Undergraduate Students Regarding Strategies That Predominantly White Institutions Can Use To Support Their Persistence In Stem, Dawn Washington, Dawn Felicia Washington

UNF Graduate Theses and Dissertations

Abstract

In this study the researcher used Q methodology to understand the shared perspectives of African American undergraduate students attending predominantly White institutions regarding strategies and supports that would help them persist in their STEM majors. Q methodology involved two phases. In phase 1, the researcher recruited 13 participants (n =10, female; n = 3, male) to respond to an open-ended questionnaire using the following directions: “List and briefly describe up to 8 strategies that predominantly White institutions can use to support African American undergraduate students’ persistence in STEM.” There were 57 opinion statements generated from this questionnaire along with …

Collective History Of Tennessee State University's Building Programs, Vallie Pursley

History of Tennessee State University Building Programs

No abstract provided.

New County Records Of Amphibians And Reptiles From South Texas, Usa, Clinton J. Guadiana, Padraic S. Robinson, Matthew S. Schalk, Drew R. Davis

School of Earth, Environmental, & Marine Sciences Faculty Publications

Several species of amphibians and reptiles reach their northern range limit in south Texas, USA. Herpetological research in the area, as well as frequent visits from amphibian and reptile enthusiasts, have helped to form a more complete understanding of amphibian and reptile distributions across the region. However, gaps in the recognized distribution of many species remain. Efforts to better document species occurrence are confounded by the lack of public land and the fact that most of south Texas is privately owned, making access to suitable habitat difficult (Schmidly et al. 2001)