Digital Commons Network^™

Characterization And Optimization Of The Synthesis Of Bioconjugated Core-Shell Silica Coated Cdte Quantum Dots, Veera Venkata Naga Manohar Devarasetty

Honors Capstone Projects and Theses

No abstract provided.

Systemic Immune-Inflammation Index Predicts Mortality In Infective Endocarditis, Hicaz Z. Agus, Serkan Kahraman, Cagdas Arslan, Ceren Yildirim, Mehmet Erturk, Ali K. Kalkan, Mustafa Yildiz

Journal of the Saudi Heart Association

Objectives: The aim of our study was to evaluate the usefulness of systemic immune-inflammation index (SII) at admission in predicting in-hospital mortality in patients with infective endocarditis. Methods: 133 definite IE patients (≥18 years) according to modified Duke criteria, treated in our tertiary care hospital between December 2009 and May 2019, were retrospectively analysed. Symptoms, comorbidities, predisposing valvular diseases, prosthetic valve, device, history of injectable drug use, blood culture results, echocardiography findings, and complications were collected. We calculated the SII as follows: SII¼platelet count£neutrophil count/lymphocyte count at admission. Results: The median age of the patients was 56 (40e66) years. Prosthetic …

Science And Scientific Discoveries: Through The Lens Of Critical Pedagogies, Aristotelis S. Gkiolmas, Anthimos Chalkidis

Taboo: The Journal of Culture and Education

No abstract provided.

April 20, 2020: Covid-19 Update, Kettering University

Communication Updates

Consistent with our commitment to do so by April 20, we now are able to make a number of decisions concerning the operation of the University through the remainder of the spring term as well as into the start of our new academic year. These, along with updated information on our plans for 2020 Commencement, are summarized below and detailed in the text of this letter.

Acue Effective Teaching Practices: Module Reflections, Nancy Wolf

Q2S Enhancing Pedagogy

This is a collection of ACUE (Association of Colleges and University Educators) implementation and reflection assignments. The Teaching Resource Center partnered with ACUE and the corresponding modules were offered to a set of accepted instructors at CSUSB. These assignments focused on teaching practices designed to enhance the learning experience for both on-ground and online instruction.

CSUSB – CNS – Department of Nursing Full-time Lecturer, Nancy Wolf, completed a 25-module course in effective teaching practices requiring the implementation of evidence-based instructional approaches. The credential is co-issued by the American Council on Education and distinguishes faculty for their commitment to educational excellence …

2020-04-20_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Effect Of Amodiaquine On Gene Expression And Apoptosis In Colorectal Cancer Cells, Holly Pyles

Honors Scholars Collaborative Projects

This study used gene expression analysis to explore the specific response to amodiaquine in HCT116 colorectal cancer cells. Real-time PCR revealed that 20 human stress and toxicity genes were upregulated by at least 3 fold in HCT116 colorectal cancer cells treated with AMQ. Of these 20 upregulated genes, 9 were found to be pro-apoptotic and 2 were DNA damage repair genes, which supports our original hypothesis that amodiaquine is inducing a stress response in these cells. These results are consistent with previous research done by Qiao et al. (2013), as DNA damage repair genes were among the genes upregulated in …

Gw Covid-19 Intelligence Reports: April 20, 2020, George Washington University

GW COVID-19 Intelligence Reports

No abstract provided.

Specialized Covid-19 Clinic Opens At Uab, Staff

Browse All News

No abstract provided.

2020-April-20-Hagemeier Polaha And Quinn Named As Presidential Fellows At Etsu, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY (April 20, 202) – East Tennessee State University President Brian Noland has named Dr. Nicholas Hagemeier, Dr. Jodi Polaha and Dr. Megan Quinn as Presidential Fellows for the fall 2020 semester.

As fellows, the three faculty members will develop and execute a project that is aligned with one of the university’s major initiatives in teaching, learning and service. The fellows will work closely with President Noland, his leadership team and ETSU Center for Teaching Excellence staff.

Hagemeier has been at ETSU since 2011. He is vice chair and associate professor of Pharmacy Practice and director of Student Professional …

Faculty Spotlight—Dr. Phil Danielson, Hannah Stanley, William Moody

DU Undergraduate Research Journal Archive

Interview with Dr. Phil Danielson

Health Concerns In Cambodia Compounded By Historical And Rural Setbacks, Ciera Dehart

Senior Honors Theses

Cambodia is a country in the Greater Mekong Subregion of Southeast Asia. The Khmer Rouge genocide in the mid 1970s produced significant setbacks in the nation’s healthcare system. While much progress has been made, rural areas still lack access to medical professionals, facilities, and equipment. Three of the most problematic diseases in Cambodia have been malaria, HIV, and tuberculosis. Due to the inadequacies of rural healthcare, treatment-resistant varieties of malaria and tuberculosis have become a serious concern for both the nation and Southeast Asia as a whole. The question of how to best provide aid to these isolated communities is …

Le Chatelier’S Principle: Identifying Cancer-Resistant Mechanisms In G1p3 Breast Cancer Cells, Alexander Rodriguez

Honors Theses

No abstract provided.

Nepal's Response To Contain Covid-19 Infection, Rano Mal Piryani, Suneel Piryani, Jay Narayan Shah

Community Health Sciences

Nepal is a landlocked country bordering two most populous countries, India and China. Nepal shares open border with India from three sides, east, south and west. And, in north with China, where the novel coronavirus infection (CVOVID-19) began in late December 2019. The first confirmed imported case in Nepal was reported in 2nd week of January 2020. The initial response of Nepal to COVID-19 were comparably slow but country geared efforts after it was declared a 'global pandemic' by WHO on 11 March, 2020. Government of Nepal's steps from 18 March, 2020 led to partial lock down and countrywide lockdown …

Biol 404- The Effects Of Dioxin-Like Polychlorinated Biphenyls (Pcbs) On The Development Of Myeloid Suppressor Cells, Emma Rogers, Ryan Servis, Talbot Thames, Amorette Barber

Virtual 2020 Spring Student Showcase for Research and Creative Inquiry

Polychlorinated biphenyls (PCBs) are a man-made organic compound consisting of two phenyl rings connected by a single bond, with any number of chlorine molecules occupying positions around the rings. They are most commonly used as a dielectric and coolant fluid in electrical generators and transformers. Manufacture has declined drastically since the 1970s in America due to their exertion of estrogen-mimicking effects in the body, although they continue to persist in harmful concentrations in the environment. PCBs are endocrine-disrupting, and through estrogenic or anti-estrogenic effects have been shown to increase breast cancer risk by changing gene expression in several genes common …

Biol 404- Effects Of Estrogen-Mimicking Compounds, Progesterone And Estriol, On Myeloid-Derived Suppressor Cell Development, Raquel Perez, Tatyana Green, Haley Bresnahan, Matthew Jones, Amorette Barber

Virtual 2020 Spring Student Showcase for Research and Creative Inquiry

Estrogen is primarily known for being a female sex hormone. It has three major subcategories estrone, estradiol, and estriol. They are known to have a role within regulation of the reproductive system and menopause. Progesterone is also a well-known steroid sex hormone that is usually associated with menstruation. These sex hormones are commonly used in oral contraceptive pills. The purpose of this study is to see if progesterone and estriol will have the same effects that estrogen has on MHC II and B7 expression. With the use of flow cytometry, T cell isolation, T cell proliferation, and ELISAs we are …

Biol 404- Effects Of Phytoestrogens - Lycopene And Trans-Resveratrol - On The Development Of Myeloid-Derived Suppressor Cells (Mdsc), Kayla Cooksey, Adrianna Doggett, Debbie Pitt, Maya Young, Amorette Barber

Virtual 2020 Spring Student Showcase for Research and Creative Inquiry

Trans-Resveratrol and Lycopene are chemical compounds found in the skin of red grapes and tomatoes respectively. This study investigates the effects of these two phytoestrogens on MDSCs.We hypothesized that these phytoestrogens will bind to estrogen receptors and block estrogenic activity, effectively decreasing the production of MDSCs in murine cells.

Biol 404- Dual Nature Of Phytoestrogens As Both Procancer And Anticancer Agents, Marcia Lanasa, Grace Freeman, Carrie Reaver, Natalie Wood, Amorette Barber

Virtual 2020 Spring Student Showcase for Research and Creative Inquiry

Phytoestrogens are plant-derived, xenoestrogenic dietary compounds found in various fruits, vegetables, soy products, teas, grains, beans, and more. There are different classes of phytoestrogens, including flavonoids, isoflavonoids, lignans, and coumestans, all of which can affect estrogen-mediated responses in different ways (Bilal et al, 2014). The aim of this project is to investigate the potential duality of phytoestrogens as both estrogen receptor antagonists in cancer cells, but also as potential activators of myeloid-derived suppressor cells. Understanding the complex role phytoestrogens play in cancer progression will prove valuable in the potential development of novel phytoestrogen-base cancer drug therapies.

Biol 404- Can A Soy Diet Mimic The Effects Of Estrogen?, Kelly Tarmon, Jonah Hottinger, Emily Humphries, Cody Gouyer, Amorette Barber

Virtual 2020 Spring Student Showcase for Research and Creative Inquiry

Phytoestrogens are estrogen-mimicking substances that can be found in many of the vegetables, beans, and grains we consume. One of the main phytoestrogens consumed by millions of people can be found in soybeans and tofu and are called isoflavones. We will be examining the first category of isoflavones, the aglycones. The aglycones are made up of daidzein, genistein, and glycitein which are found in soy products. We will determine the function of aglycones using flow cytometry by comparing the effect of these three compounds, estradiol, and the media given. As aglycones are estrogen mimicking compounds, we believe these three phytoestrogens …

The Urgency Of Global Awareness, Julius A. Amin

Proceedings: 2020 Global Voices on the University of Dayton Campus

The 2020 Global Voices Symposium occurred at a momentous time in the world. During the Symposium there was chatter about the looming threat of novel coronavirus (COVID-19), which already had ravaged communities in China. Few predicted its rapid spread. Less than a week after the Symposium, many governors and local leaders in the U.S. ordered K-12 schools and universities to close as a preliminary measure to curb the spread of the virus. Three weeks after the Symposium, eight states in the U.S. issued shelter-in-place orders for their citizens, and other states were contemplating similar action. Repeatedly, people were being told …

Efficacy Of Glutathione Therapy In Relieving Dyspnea Associated With Covid-19 Pneumonia: A Report Of 2 Cases, Richard I. Horowtiz, Phyllis R. Freeeman, James Bruzzese

Publications and Research

Purpose: Infection with COVID-19 potentially can result in severe outcomes and death from “cytokine storm syndrome”, resulting in novel coronavirus pneumonia (NCP) with severe dyspnea, acute respiratory distress syndrome (ARDS), fulminant myocarditis and multiorgan dysfunction with or without disseminated intravascular coagulation. No published treatment to date has been shown to adequately control the inflammation and respiratory symptoms associated with COVID-19, apart from oxygen therapy and assisted ventilation. We evaluated the effects of using high dose oral and/or IV glutathione in the treatment of 2 patients with dyspnea secondary to COVID-19 pneumonia.

Methods: Two patients living in New York City …

Comatose Within 6 Weeks, But Still Alive After 3 Years, Creutzfeldt‐Jakob Disease With Unusual Progression, Julia Kathleen Christopher, Brian Khong, Amin Abolfazli, Antonio Liu

School of Medicine Faculty Research

Creutzfeldt‐Jakob disease (CJD) should still be considered in a patient presenting with rapidly progressive dementia and negative CSF 14‐3‐3 protein and RT‐QulC. Treatable causes of encephalopathy must be ruled out. Neurodegenerative diseases must also be considered.

2020-04-18_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

A Study Of Cholera Transmission, Urmi Ghosh-Dastidar

Open Educational Resources

A recent cholera outbreak in Haiti brought public attention to this disease. Cholera, a diarrheal disease, is caused by an intestinal bacterium, and if not addressed in a timely manner may become fatal. During the project described here, the students will learn how to solve and address a practical problem such as cholera transmission using various mathematical tools. Students will learn to develop a differential equation model based on practical scenarios, analyze the model using mathematics as well as numerical simulation, and finally describe the results in words that are understandable by the people who are not specialists in this …

Combating Sars-Cov-2: Leveraging Microbicidal Experiences With Other Emerging/Re-Emerging Viruses, M. Khalid Ijaz, Syed A. Sattar, Joseph R. Rubino, Raymond W. Nims, Charles P. Gerba

Publications and Research

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan City, China, late in December 2019 is another example of an emerging zoonotic virus that threatens public health and international travel and commerce. When such a virus emerges, there is often insufficient specific information available on mechanisms of virus dissemination from animal to human or from person to person, on the level or route of infection transmissibility or of viral release in body secretions/excretions, and on the survival of virus in aerosols or on surfaces. The effectiveness of available virucidal agents and hygiene practices as interventions for disrupting …

The Population Health Outcomes And Information Exchange (Phoenix) Program - A Transformative Approach To Reduce The Burden Of Chronic Disease, Steven J. Korzeniewski, Carla Bezold, Jason T. Carbone, Shooshan Danagoulian, Bethany Foster, Dawn Misra, Maher M. El-Masri, Dongxiao Zhu, Robert Welch, Lauren Meloche, Alex B. Hill, Phillip Levy

Urban Studies and Planning Faculty Research Publications

This concept article introduces a transformative vision to reduce the population burden of chronic disease by focusing on data integration, analytics, implementation and community engagement. Known as PHOENIX (The Population Health OutcomEs aNd Information EXchange), the approach leverages a state level health information exchange and multiple other resources to facilitate the integration of clinical and social determinants of health data with a goal of achieving true population health monitoring and management. After reviewing historical context, we describe how multilevel and multimodal data can be used to facilitate core public health services, before discussing the controversies and challenges that lie ahead.

The Role Of Diet In The Onset Of Depression: A Biochemical Connection Between Nutrition And Mental Health, Katlin Wildeman

Senior Honors Theses

Depression is a major clinical concern, having a complex onset and the presence of multiple, often unidentifiable causes. Depression affects millions of individuals worldwide, with a high prevalence in regions of the world with a Western-style diet as compared to regions with a Mediterranean diet. A Western-style diet consists of foods high in sugar, fat, and processed meats and grains, whereas the Mediterranean diet contains significantly more vegetables, fruits, lean meats, and whole grains. The link between diet and mental health disorders has implications for individuals of all ages who are hesitant to turn to medication. In addition to presenting …

Editorial. Covid-19 And Spinal Surgery., Zoher Ghogawala, Shekar Kurpad, Asdrubal Falavigna, Michael W Groff, Daniel M Sciubba, Jau-Ching Wu, Paul Park, Sigurd Berven, Daniel J Hoh, Erica F Bisson, Michael P Steinmetz, Marjorie C Wang, Dean Chou, Charles A Sansur, Justin S Smith, Luis M Tumialán

Neurosurgery

No abstract provided.

April 17, 2020: Covid-19 Update, Kettering University

Communication Updates

The Kettering University Student Emergency Fund has been established to provide financial assistance to current undergraduate and graduate students impacted by the Covid-19 crisis.

2020-04-17_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …