Digital Commons Network^™

Optimising Ventilator Use During The Covid-19 Pandemic, Sadaf Sheikh, Muhammad Akbar Baig

Department of Emergency Medicine

Hypoxemia is the most common cause for hospitalization in COVID-19 patients. Acute hypoxemic respiratory failure or acute respiratory distress syndrome (ARDS) is the most common complication in COVID-19 patients. Close monitoring of respiratory decompensation is essential. Supplemental oxygen, high flow nasal canula, non-invasive ventilation and endotracheal intubation are the most commonly suggested methods to improve oxygenation. Early intubation with pre-oxygenation, modified rapid sequence intubation and intubation using a video laryngoscope has been advised as a strategy including lung protective ventilation, prone position ventilation, adequate sedation and extracorporeal membrane oxygenation. Strict personal precautions and challenges related to airway management has been …

Mechanical Thrombectomy In The Era Of The Covid-19 Pandemic: Emergency Preparedness For Neuroscience Teams: A Guidance Statement From The Society Of Vascular And Interventional Neurology, Italo Linfante

All Publications

No abstract provided.

Authorship Patterns In Eosinophilia Research Literature: A Scientometric Analysis, Chithiraivel S, Jeyshankar R, Sivasekaran K

Library Philosophy and Practice (e-journal)

The present study the examined the authorship patterns in the field of eosinophilia literature based on the publications indexed in the Web of Science Core Collection during the period from 1998 to 2017. Totally 70337 researchers have contributed 12118 publications produced over 1,797 journals in the subject of eosinophilia. Findings of the analysis revealed that the author’s productivity examines the trend in understanding the research process in any discipline of science; maximum records of 1625 publications produce by four authors. It is found that the degree of collaboration is an increasing and decreasing trend. This study includes an overview of …

Research Trends On Coronavirus (Covid-19) : A Bibliometric Analysis Between 2010– March 2020, Mahendra Kumar Sahu Dr, Chetan Gk Dr, Siba Prasad Panda Dr

Library Philosophy and Practice (e-journal)

Coronavirus is a respiratory syndrome, a virus causing stern pneumonia in humans. The results of the Pandemic virus is high mortality, respiratory infections including the common cold, high fever etc. The main objective of the study is to explore the publications trends of CoronavCirus research by using R-Studio. Scopus database has been used to extract the bibliographic metadata of the publication between 2010 and April 2020. A total of 10515 documents were published across the globe on Coronavirus (Covid-19) during the assessment period under consideration. The result of the current study suggests that the earlier outbreak of Coronavirus were understudied. …

Learning Transferable Deep Convolutional Neural Networks For The Classification Of Bacterial Virulence Factors, Dandan Zheng, Guansong Pang, Bo Liu, Lihong Chen, Jian Yang

Research Collection School Of Computing and Information Systems

Motivation: Identification of virulence factors (VFs) is critical to the elucidation of bacterial pathogenesis and prevention of related infectious diseases. Current computational methods for VF prediction focus on binary classification or involve only several class(es) of VFs with sufficient samples. However, thousands of VF classes are present in real-world scenarios, and many of them only have a very limited number of samples available.Results: We first construct a large VF dataset, covering 3446 VF classes with 160 495 sequences, and then propose deep convolutional neural network models for VF classification. We show that (i) for common VF classes with sufficient samples, …

Immunohistochemical Expression Of P16 Protein And Tgf Β1 In Mice Liver Exposed To Fumonisin B1, Sinai W. Mohammed, Basim M. Khashman, Noorulhuda F. Khalaf, Munira Ch. Ismeeal, Maysaa Kadhim Al-Malkey

Baghdad Science Journal

Fumonisin B1 (FB1) is a mycotoxin produced in some grains (mainly corn) by Fusarium species. Due to a structural similarity between FB1 and sphinganine, sphingolipids metabolism is inhibited. Such inhibition plays a critical role in cell to cell singling and structure of lipoprotein; therefore FB1 has been suggested to have a relationship with human and animal cancer. This research is planned to study the effect of FB1 on male mice at two doses (20 and 30 µg/ ml) on the expression of TGF-β1 and p16 in liver cells. Three groups of Swiss albino male mice; each group was orally administrated …

Homoeopathy In The Management Of Infectious Diseases: Different Facets Of Its Use And Implications For The Future, Roja Varanasi, Debadatta Nayak

Indian Journal of Research in Homoeopathy

Background: Infectious diseases are a major challenge to humanity and public health at large. Objective: The aim of this study is to conduct a systematic narrative review of the clinical research evidence for homeopathy in the management of infectious diseases. Methods: A comprehensive search of major biomedical databases: Cochrane Database of Systematic Reviews, Pubmed, Core-Hom, AYUSH Research Portal) and other individual journal sites were conducted. Relevant research published between 1999 and 2019 was categorised by study type, clinical condition and causative pathogen. Results: The literature search of two decades (1999–2019) gathered 86 articles: Meta-analysis (n = 1), systematic reviews (n …

Homoeopathic Nosodes, A Neglected Approach For Epidemics: A Critical Review, Debadatta Nayak, Roja Varanasi

Indian Journal of Research in Homoeopathy

Background: Nosodes are the homoeopathic medicines prepared from diseased products of biological origin. These are commonly used in clinical practice for the prophylaxis and treatment of ailments including infectious diseases. Objective: This review aims at the usage of nosodes for the management of epidemics. Methods: The homoeopathic research literature was searched to find examples of the use of nosodes in different ways and to evaluate their role and position in homoeopathic practice with special reference to epidemic diseases. Results: Research evidence for use of the nosodes as prophylactics and for the treatment of various infectious and non-infectious diseases is emerging. …

World Homoeopathy Day 2020: Connecting Digitally During The Adversities Of Covid-19 Lockdown, Deepti Chalia, O Verma, Kavita Bharti

Indian Journal of Research in Homoeopathy

The Central Council for Research in Homoeopathy (CCRH), with support from the Ministry of AYUSH, Government of India, organised its first Webinar on World Homoeopathy Day on 10 April 2020 to commemorate the birth anniversary of the founder of Homoeopathy, Dr Samuel Hahnemann. Considering the need of hour and utilising the advancements of digital platforms, the CCRH decided to organise this webinar focusing on the role of Homoeopathy in COVID-19, for the homoeopathic fraternity and to unite them digitally. The webinar was inaugurated by Shri. Shripad Naik, Minister of State (IC), Ministry of AYUSH; Vaidya Rajesh Kotecha, Secretary, Sh. PK …

Preparing To Cocreate: Using Learning Circles To Ready Extension Professionals For Meaningful Stakeholder Engagement, Bob Bertsch, Jill Heemstra, Doug Golick

Journal of Extension

Extension professionals are being asked to address complex public issues. Doing so requires cocreative approaches that engage, in a significant way, the people affected by these issues. Successful engagement, however, requires specific skills and a cocreative mind-set. Extension professionals in two states participated in learning circles to improve their engagement skills. Using a survey and interviews, we studied the impact of the learning circle experience on participants. We found that learning circles helped participants practice colearning, build relationships, and change their mind-sets in ways that could move their work toward more cocreative efforts.

Modeling The Spread Of Measles, Alexandria Le Beau

Electronic Theses, Projects, and Dissertations

The measles virus has been around since the 9th century. Throughout the years measles have become less problematic in certain areas of the world due to research and the creation of vaccinations. Sadly, not all countries are fortunate enough to have adequate access to the vaccination, which leads to yearly outbreaks.

The goal of this project is to experiment with different mathematical growth models and examine their suitability for modeling outbreaks of measles. We will compare and contrast the exponential model, the logistic model, the SIR model, and the SEIR model. In addition, we will show how the epidemiological models …

Preparing To Cocreate: Using Learning Circles To Readyextension Professionals For Meaningful Stakeholderengagement, Bob Bertsch, Jill Heemstra, Doug Golick

Department of Entomology: Faculty Publications

Extension professionals are being asked to address complex public issues. Doing so requires cocreativeapproaches that engage, in a significant way, the people affected by these issues. Successful engagement,however, requires specific skills and a cocreative mind-set. Extension professionals in two states participatedin learning circles to improve their engagement skills. Using a survey and interviews, we studied the impact ofthe learning circle experience on participants. We found that learning circles helped participants practicecolearning, build relationships, and change their mind-sets in ways that could move their work toward morecocreative efforts.

Determining The Knowledge Of Primary Healthcare (Phc) Physicians And Factors Influencing Practices In The Implementation Of The Catch-Up Vaccination Program In Phc Clinics In Dammam, Saudi Arabia, Rawan S. Alfaraj, Amal Alshehab, Shahid A. Latif

Saudi Medical Journal

Objectives: To determine the knowledge of primary healthcare (PHC) physicians and factors influencing implementation of the catch-up vaccination program in PHC clinics in Dammam, Saudi Arabia. Methods: A cross-sectional study was conducted with a sample of 136 general and family physicians between October 2018 and August 2019 in PHC clinics. A self-administered questionnaire related to knowledge, practices, and factors affecting their practices regarding vaccination was given to participants. Their responses were assessed for level of knowledge, practices regarding the vaccination program, and factors affecting their practices, and then compared between family and general physicians. Results: The majority of physicians (60%) …

Children’S Mercy Covid-19 Venous Thromboembolism (Vte) Prophylactic Guidelines, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Care Process Models)

No abstract provided.

Initial Acute Otitis Media Antibiotic Treatment, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Care Process Models)

No abstract provided.

Analyzing Service Barriers And Risk Factors For Reentry Among Formerly Incarcerated Adults, Agustina Alejandra Sepulveda

Electronic Theses, Projects, and Dissertations

Recidivism is a growing problem affecting formerly incarcerated adults struggling with reentry into society. After release, most individuals are dealing with barriers in their environment that affect their access to substance abuse and mental health treatment, which can be important to reducing recidivism. Thus, this study sought to understand the various service barriers and risk factors to reentry among formerly incarcerated individuals to help increase awareness of some of the challenges the reentry population is facing.

Self-administered surveys focusing on housing, employment, public assistance, and mental health barriers were collected among formerly incarcerated individuals from Southern California (n=103). Bivariate chi-square …

An Autoencoder And Artificial Neural Network-Based Method To Estimate Parity Status Of Wild Mosquitoes From Near-Infrared Spectra, Masabho Peter Milali, Samson S. Kiware, Nicodem J. Govella, Fredros Okumu, Naveen K. Bansal, Serdar Bozdag, Jacques D. Charlwood, Marta F. Maia, Sheila B. Ogoma, Floyd E. Dowell, George Corliss, Maggy T. Sikulu-Lord, Richard J. Povinelli

Electrical and Computer Engineering Faculty Research and Publications

After mating, female mosquitoes need animal blood to develop their eggs. In the process of acquiring blood, they may acquire pathogens, which may cause different diseases in humans such as malaria, zika, dengue, and chikungunya. Therefore, knowing the parity status of mosquitoes is useful in control and evaluation of infectious diseases transmitted by mosquitoes, where parous mosquitoes are assumed to be potentially infectious. Ovary dissections, which are currently used to determine the parity status of mosquitoes, are very tedious and limited to few experts. An alternative to ovary dissections is near-infrared spectroscopy (NIRS), which can estimate the age in days …

Seroprevalence And Some Demographic Factors Associated With Toxoplasma Gondii Infection Among Male Population In Duhok Province/Iraq, Janan M. Salih, Wijdan M.S. Mero, Souzan H. Eassa

Baghdad Science Journal

The present study aims to investigate the seroprevalence rate of Toxoplasma gondiiinfection and its relation to some demographic factors among malesin Duhok province/Iraq. A total of 424 random blood samples were collected from the male population of different ages (18-60) years and different social-economic classes. Out of 424 samples examined, 108 (25.47%) were seropositive to the anti- T. gondii antibodies; 88 (20.75%) were found seropositive for IgG, while 20 (4.72%) samples were seropositive for IgM. Regarding occupation, the highest percentage for chronic toxoplasmosis was reported in workers followed by policemen and pensioners at rates of 23.96%, 23.6%, and 23.07%, respectively. …

N Y State Dent J June-July 2020

The New York State Dental Journal

The New York State Dental Journal (NYSDJ) is produced by the New York State Dental Association (NYSDA) six times a year, in January, March, April, July, September and November. Each issue features clinical and scientific articles written by researchers and practitioners from around the globe and is subject to review by a panel of specialists convened by the Editor.

Issues include cover and feature articles alongside regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Understanding Human Astrovirus From Pathogenesis To Treatment, Virginia Hargest

Theses and Dissertations (ETD)

While human astroviruses (HAstV) were discovered nearly 45 years ago, these small positive-sense RNA viruses remain critically understudied. These studies provide fundamental new research on astrovirus pathogenesis and disruption of the gut epithelium by induction of epithelial-mesenchymal transition (EMT) following astrovirus infection. Here we characterize HAstV-induced EMT as an upregulation of SNAI1 and VIM with a down regulation of CDH1 and OCLN, loss of cell-cell junctions most notably at 18 hours post-infection (hpi), and loss of cellular polarity by 24 hpi. While active transforming growth factor- (TGF-) increases during HAstV infection, inhibition of TGF- signaling does not hinder EMT induction. …

Prognosticating Covid-19: A Need For Africa-Specific Laboratory Predictors, Geoffrey Omuse, Janet Maranga, Abubakar Abdillah, Daniel Maina

Pathology, East Africa

No Abstract

Genetic Counseling And Preventive Medicine In Bosnia And Herzegovina, Philip C. Aka

California Western International Law Journal

No abstract provided.

Hypoxia-Inducible Factor (Hif)-2Α Reprograms Liver Macrophages To Protect Against Acute Liver Injury Via The Production Of Interleukin-6, Rachel Y Gao, Meng Wang, Qihui Liu, Dechun Feng, Yankai Wen, Yang Xia, Sean P Colgan, Holger K Eltzschig, Cynthia Ju

Faculty, Staff and Student Publications

BACKGROUND AND AIMS: Acetaminophen (APAP) overdose represents the most frequent cause of acute liver failure, resulting in death or liver transplantation in more than one third of patients in the United States. The effectiveness of the only antidote, N-acetylcysteine, declines rapidly after APAP ingestion, long before patients are admitted to the clinic with symptoms of severe liver injury. The direct hepatotoxicity of APAP triggers a cascade of innate immune responses that may exacerbate or limit the progression of tissue damage. A better understanding of this complex mechanism will help uncover targets for therapeutic interventions.

APPROACH AND RESULTS: We observed that …

Seroprevalence, Biochemical Investigation And Risk Factor Assessment For Hbv & Hcv Infection In Hospital Based Patients Of Islamabad, Pakistan, Narmeen Adnan Rana, Bushra Munir, Nazeer Hussain, Nazia Imtiaz, Muhammad Asif Gondal Dr., Fahed Parvaiz Dr.

Journal of Bioresource Management

Viral hepatitis poses a serious threat to mankind. Hepatitis B and C Virus are blood borne pathogens that affect millions of individually globally. This study was conducted on a hospital-based population in Islamabad, Pakistan over a period of 4 months, utilizing ELISA as the diagnostic technique which suggested a higher seroprevalence rate for both HBV and HCV i.e. 2.07% and 8.24% respectively. A correlational analysis of the biochemical parameters of these individuals with HBV and HCV infection was carried out and the results indicated a positive correlation of HBV with Alkaline Phosphatase (ALP), HCV with Total Bilirubin (TBil) and both …

Ssi Postoperative Surgical Bundle: Summary, Children's Mercy Kansas City

Clinical Critically Appraised Topics

No abstract provided.

Design Thinking Intervention In Healthcare, Mohammed Ali Alshehri

Dissertations and Theses Collection (Open Access)

The healthcare industry is currently experiencing numerous challenges. Lack of skilled and innovative practitioners in healthcare organizations disrupts operational functions, administration, and service delivery. Dentistry is full of complex problems. There is currently a significant gap between the desired solutions dental providers offer to solve these problems and the actual outcomes. So, dental providers must rethink their approach to solving healthcare problems. One of the desirable approaches is design thinking.

Application of design thinking in business and healthcare has demonstrated improved results. In this research, the objective was to investigate the application of design thinking in dentistry and its effects …

Community And Health Workers’ Responses To Guidelines During Covid-19 Pandemic- A Critical Review, Ansuman Swain, Parul Malik, Kirtimayee Soumyadarshinee, Arathi P. Rao

Manipal Journal of Medical Sciences

On 30th January 2020, World Health Organization (WHO) declared the Coronavirus disease (COVID-19) as a Public Health Emergency of International Concern (PHEIC), and the first case in the Indian subcontinent was reported. Subsequently, following the directives issued by WHO, the nodal agencies related to health care services in the country like the Indian Council of Medical Research (ICMR) and Ministry of Health and Family Welfare (MoHFW); have been issuing guidelines to public and professionals to enable and equip them to combat and contain the pandemic. Guidelines about health care personnel, necessary infrastructure, personal protective equipment, prophylaxis, access and availability of …

And This Too Shall Pass …!, Sunil R

Manipal Journal of Medical Sciences

No abstract provided.

Bones, Burials, And The Riddle Of Truth: Reconstructing The Past Through What Has Been Left Behind, Jelena M. Begonja

Dissertations, Theses, and Capstone Projects

Mortuary archaeology is known to be the study of human remains and burials. The primary focus of this work has been to study all of the elements associated in burials to learn more about the burial practices and rituals in a group’s culture, however, there is much more potential in studying burial sites than just learning about a group’s burial rituals and practices. This thesis will demonstrate that it is indeed possible to make different inferences about the rest of people’s daily lives, and the truth, based from materials found in studying burials alone. For some groups without much existing …

Multicenter Clinical Evaluation Of The Revogene Strep A Molecular Assay For Detection Of Streptococcus Pyogenes From Throat Swab Specimens, Dithi Banerjee, Jeff Michael, B. Schmitt, H. Salimnia, N. Mhaissen, D. M. Goldfarb, P. Lachance, M. L. Faron, T. Aufderheide, N. Ledeboer, A. Weissfeld, Rangaraj Selvarangan

Manuscripts, Articles, Book Chapters and Other Papers

Copyright © 2020 Banerjee et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license Group A streptococcus (GAS) species cause bacterial pharyngitis in both adults and children. Early and accurate diagnosis of GAS is important for appropriate antibiotic therapy to prevent GAS sequalae. The Revogene Strep A molecular assay (Meridian Bioscience Canada Inc, Quebec City, QC, Canada) is an automated real-time PCR assay for GAS detection from throat swab specimens within approximately 70 min. This multicenter prospective study evaluated the performance of the Revogene Strep A molecular assay compared to that …