Digital Commons Network^™

The Effect Of Hibiscus.Sabdariffa. L On Blood Pressure And Arterial Stiffness In Humans, Basirat Tolulope Shittu

Dissertations, Master's Theses and Master's Reports

Cardiovascular diseases (CVD) are the foremost cause of death worldwide. The main risk factor for CVD is uncontrolled hypertension (HTN). The prescription of only anti-hypertensive regimens in the management of HTN is becoming more challenging due to the high cost and adverse effects linked to the persistent usage of the drugs. Eighteen participants completed the study by consuming 2g of Hibiscus sabdariffa or oolong tea twice daily for six weeks. We lost an additional twelve participants in the study due to the COVID-19 pandemic. Central arterial stiffness was analyzed as cfPWV using applanation tonometry technique. The HS tea intervention (n=11) …

The Anesthesia Continuing Education Market And The Value Creation From A Sustainable Unified Platform, Jefferson Souza

MUSC Theses and Dissertations

Practicing anesthesia professionals in the United States are all governed by various profession-specific regulatory bodies that mandate continuing education (CE) requirements. To date, no unified resource exists for anesthesia professionals (i.e., Anesthesiologists, Certified Registered Nurse Anesthetists, and Anesthesiologist Assistants) to explore the CE offerings available within the marketplace. This study endeavored to convey the potential value of a unified anesthesia CE resource. It investigated how to cultivate a sustainable platform to potentially improve how anesthesia professionals search available CE offerings and to potentially enhance how anesthesia CE providers reach anesthesia professionals. This qualitative study was conducted utilizing an integrative review …

The Influence Of Diet On The Gut Microbiome, Kayla Wede

Health and Nutritional Sciences Graduate Students Plan B Capstone Projects

There is growing research that directly looks at the relationship between the human diet and the gut microbiome. This paper is a narrative review of the current literature on how the human diet can influence the gut microbiome. Without a healthy gut, bacterial imbalances can occur which have been linked to health complications. There are many factors that affect the gut microbiome such as diet, medications, and exercise. There is also limited research that looks at the macronutrients and their role in gut health. It is known that the type of food that people consume is a major influencer of …

Persistence: 2019-20 Report Of The President, Office Of The President, Gonzaga University

Office of the President Publications

Each year, Gonzaga University's Office of the President produces an annual Report of the President. This publication that highlights just a few of the many accomplishments over the previous academic year, and is intended to convey gratitude to our Trustees and Regents, benefactors, and many supporters.

The Burden Of Unintentional Drowning: Global, Regional And National Estimates Of Mortality From The Global Burden Of Disease 2017 Study, Richard Charles Franklin, Amy E. Peden, Erin B. Hamilton, Catherine Bisignano

Open Access archive

Background: Drowning is a leading cause of injury-related mortality globally. Unintentional drowning (International Classification of Diseases (ICD) 10 codes W65-74 and ICD9 E910) is one of the 30 mutually exclusive and collectively exhaustive causes of injury-related mortality in the Global Burden of Disease (GBD) study. This study's objective is to describe unintentional drowning using GBD estimates from 1990 to 2017. Methods: Unintentional drowning from GBD 2017 was estimated for cause-specific mortality and years of life lost (YLLs), age, sex, country, region, Socio-demographic Index (SDI) quintile, and trends from 1990 to 2017. GBD 2017 used standard GBD methods for estimating mortality …

The Tera Multi Terrain Mobility Aid Chassis, Colton Kemp, Daniel Nicoll, Ibrahim Suleiman, Mohammad Alyami

Williams Honors College, Honors Research Projects

The natural environment poses a significant number of obstacles and dynamic settings that makes mobility difficult for those with physical and mobility impairments. To approach this problem, a suspension was designed using inspiration from the early Mars rovers developed by NASA for traversing the varied Martian landscape. The course of the project followed the direction of a start-up through problem identification, early design generation and review, and final design production. The project outcome, through client request and proven market research, aimed to produce a multi-terrain wheelchair. The final product is a kinematic body with mobile front “legs” and a rotational …

Effects Of Nutrition, Hydration, Exertion, And Sleep On Injury And Illness In Female Collegiate Soccer Players, Ronald Corbit Franks Jr.

Electronic Theses and Dissertations

ABSTRACT Injury and illness rates in collegiate athletics continue to rise. Women’s soccer tends to have high numbers of injuries because it is a contact sport. Research has shown that there are several contributing factors to injury and illness rate in collegiate athletics. This study will provide an in depth look at female athletes, more specifically female collegiate soccer players and several factors – including dietary intake, hydration status, exertion and sleep that may attribute to injury and illness in this population. Researchers utilized weekly 3-day diet records, daily urine specific gravity, training load and self-reported sleep quantity to establish …

Assessment Of Heat Stress For Outdoor Work Conditions In Saudi Arabia, Jamal Alanazi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Outdoor workers have an increased risk of heat stress in Saudi Arabia since it is one of the hottest places in the Middle East. Recently, the government decided to limit outdoor work hours during the months of June, July, and August every year, and banned working under the direct sunlight from 12:00 to 03:00 p.m., although outdoor workers in the petroleum, natural gas, or emergency maintenance work industries are exempt from this prohibition. Traditionally, the efforts by safety and health professionals to mitigate work-related heat injury has been directed toward the assessment of environmental heat stress (e.g., wet-bulb globe temperature), …

Community Health Majors, Public Health

Program Revisions/Additions

No abstract provided.

Health Administration Program, Public Health

Program Revisions/Additions

No abstract provided.

Mindfulness, Aortic Wave Reflection, And Arterial Stiffness, Sarah Lewallen

Dissertations, Master's Theses and Master's Reports

Cardiovascular disease and hypertension are leading causes of death worldwide. The mitigation of high blood pressure is essential in decreasing the prevalence of cardiovascular-related deaths worldwide. Stress and anxiety are known to play a role in augmenting blood pressure in individuals of all ages. This increase in pressure can result in premature stiffening of large arteries in systemic circulation. Mindfulness is an ancient, non-secular practice which aids in stress reduction. Decentering, an aspect of mindfulness, involves accepting thoughts as transient rather than permanent associations. The purpose of this project was to examine the relationship between cardiovascular health and mindfulness practices. …

From Synthesis To Utilization: The Ins And Outs Of Mitochondrial Heme, Samantha A. Swenson, Courtney M. Moore, Jason R. Marcero, Amy E. Medlock, Amit R. Reddi, Oleh Khalimonchuk

Department of Biochemistry: Faculty Publications

Heme is a ubiquitous and essential iron containing metallo-organic cofactor required for virtually all aerobic life. Heme synthesis is initiated and completed in mitochondria, followed by certain covalent modifications and/or its delivery to apo-hemoproteins residing throughout the cell. While the biochemical aspects of heme biosynthetic reactions are well understood, the trafficking of newly synthesized heme—a highly reactive and inherently toxic compound—and its subsequent delivery to target proteins remain far from clear. In this review, we summarize current knowledge about heme biosynthesis and trafficking within and outside of the mitochondria.

Structural And Functional Characterization Of Cazyme And Cazyme-Related Proteins From: Bacteroides Thetaiotaomicron And Porphyromonas Gingivalis: Two Abundant Colonizers Of The Human Microbiome, James Stevenson

Theses and Dissertations (Comprehensive)

The human body consists of approximately 30 trillion cells, while non-human microbes that reside on and within the body outnumber human somatic cells by a factor of 1.3 – 2.3. The interplay between our cells and those of the colonizing microorganisms affect physiology in a multitude of ways, both beneficial and detrimental. Microbes found in the oral cavity, such as the Red Complex member Porphyromonas gingivalis, are associated with pathology, namely periodontal diseases including gum deterioration, tooth decay, and loss of underlying alveolar bone. At the other end of the gastrointestinal tract, microbes such as Bacteroides thetaiotaomicron are found …

Adapting To Extreme Heat: Social, Atmospheric, And Infrastructure Impacts Of Air Conditioning In Megacities - The Case Of New York City, Harold Gamarro

Dissertations and Theses

Extreme heat events are becoming more frequent and intense in most large cities. Built-up surfaces also limit cooling mechanisms, leading to warmer conditions in cities, a phenomenon called the Urban Heat Island (UHI). This presents major challenges to reduce adverse health effects of hot weather, particularly in vulnerable populations like the elderly and low-income communities. Here we explore the overall impacts of increasing air conditioning (AC) system adoption in residences as an adaptive measure to reduce human health risks under heat waves, with New York City (NYC) as a case study. This study uses AC adoption data from the 2017 …

Epigenetic Alterations In Response To Multi-Walled Carbon Nanotubes And Dha Diet Modification, Elizabeth Michelle Cole

Graduate Student Theses, Dissertations, & Professional Papers

Multi-walled carbon nanotubes (MWCNTs) are a class of engineered nanomaterials that pose airborne exposure risks to human health. Immense variations in physical properties such as size and shape complicate understanding the underlying mechanisms and consequences of MWCNT exposures. There are concerns that exposures can lead to chronic pulmonary inflammation and fibrosis diseases, as is the case with other more known ultra-fine respirable materials with similar physical properties, such as crystalline silica and asbestos. Pro-inflammatory diseases can be regulated by epigenetic changes, which can be influenced by environment, including diet. Docosahexaenoic acid (DHA) is an omega-3 fatty acid that may promote …

The Impact Of A Curricular Change On Undergraduate Human Anatomy And Physiology Students’ Academic Behavior And Performance, Jessica A. Adams

Open Access Dissertations

This dissertation explores learning in context. Undergraduate introductory human anatomy and human physiology courses are either taught as discipline-specific or integrated anatomy and physiology (A&P) sequences. These courses are critically important to future health care professionals yet a consensus is lacking on the optimal course approach. Our institution underwent a curricular revision to change pedagogical methodologies from discipline-specific human anatomy and human physiology to an integrated A&P I and II sequence. Thus, providing a unique opportunity to study the potential impact of contextual learning. Specifically, over three years the effects integrating physiological concepts had on anatomy education were explored as …

Psychosocial And Physiological Correlates Of Chronic Pain In Persons Living With Hiv, Michael Owens

All ETDs from UAB

Due to recent advancements in antiretroviral therapy (ART), people living with HIV (PLWH) who respond well and remain adherent to their medication regimens are achieving “near normal” life expectancies. As a result, HIV is no longer considered a death sentence, but rather a chronic health condition to be managed. However, the longer a person lives with the virus, the more prone to HIV-associated chronic diseases he or she becomes. One particularly important health condition with the potential to significantly and negatively impact quality of life is chronic pain. The prevalence rates of chronic pain in PLWH are estimated to be …

Mcnp Design Of Radiation Shielding For Pulsed Fusion Propulsion, David Jason Hewitt

Theses

Pulsed fusion, fission and fission-fusion hybrid systems are currently being studied for advanced propulsion to enable rapid interplanetary space travel. A testbed for evaluating these technologies at the University of Alabama in Huntsville, called Charger-1, utilizes a form of Magneto-Inertial Fusion to implode small plasma loads with z-pinch that will produce thrust when coupled with a magnetic nozzle. Like all forms of nuclear propulsion, this experiment will also be able to produce significant amounts of ionizing radiation in the form of high energy neutrons and photons that need mitigation to protect personnel and equipment. The laboratory housing this testbed has …

Evolution Of Senescence In Humans - The Rift Between Lifespan And Healthspan, Mitch Beito

Undergraduate Student Research Awards

No abstract provided.

Piezoresistive Disposable Weight Sensor With Increased Sensitivity, Kuter Erdi̇l, Tuğçe Ayraç, Ömer Gökalp Akcan, Yi̇ği̇t Dağhan Gökdel

Turkish Journal of Electrical Engineering and Computer Sciences

This study presents the design, simulation, implementation, and experimental characterization of a paperbased perforated disposable weight sensor system with a double piezoresistive layer. The demonstrated system is designed to achieve highly sensitive weight sensing operations with low-cost materials. For that purpose, the main fabrication material of the proposed disposable sensor is selected as a 289 $\mu$m thick Strathmore 400 series Bristol paper. Approximately 48 $\mu$m thick piezoresistive graphite paste is coated onto both sides of the paper-based cantilever beam with the aim of acquiring more sensitive weight-sensing capability. Additionally, the proposed paper-based structure has rows of closely spaced perforations at …

Familial Caregivers’ Perceptions Of Alcohol Use Among Mature Adults Residing In Assisted Living Communities, Lemeshia Meshana Agee Chambers

Walden Dissertations and Doctoral Studies

Research suggests that alcohol abuse is among the 8 primary causes of death for mature adults, which includes individuals age 65 and older. Alcohol use is a growing, unaddressed, public health concern among this referent population. Additionally, as mature adults enter the retirement phase of their lives, many of them transition to residing in assisted living communities. The purpose of this study was to explore mature adults’ alcohol use in assisted living communities and how such use, as perceived by the familial caregivers, affected the mature adults’ ability to age successfully. The population under study consisted of 8 familial caregivers, …

Intrinsic Motivations And Perceived Benefits Of U.S. Males For Taking Dimethyltryptamine, Timothy Raymond Kazmarek

Walden Dissertations and Doctoral Studies

Dimethyltryptamine (DMT) is a psychedelic drug which has a rapidly increasing user rate, giving rise to concern amongst law enforcement and public health officials around the world. While previous researchers have primarily focused their examinations of motivations for DMT use internationally with diverse populations, this study was an investigation of DMT use in the United States among its most prevalent user demographic, adult men. The purpose of this study was to bridge the gap between knowledge of motivations for DMT use internationally and lack of knowledge domestically. The theoretical foundation for this study was comprised of the self-efficacy theory and …

Strategies Insurance Company Managers Use To Retain Employees, Christopher Ramel Robinson

Walden Dissertations and Doctoral Studies

Insurance business managers who fail to retain employees experience reduced profitability and productivity. Employee retention issues in the insurance industry negatively affect recruitment and training costs, employee engagement, and operational efficiency. Grounded in Herzberg’s 2-factor theory of motivation, the purpose of this qualitative multiple case study was to explore strategies that insurance company managers use to retain employees. Data were collected through semistructured interviews with 5 insurance managers in New York and a review of company documents on employee retention strategies. Data were analyzed using Yin’s 5-step process of compiling, disassembling, reassembling, interpreting, and concluding data. The 3 themes that …

Implementation Of Wearable Sensing Technology For Movement: Pushing Forward Into The Routine Physical Rehabilitation Care Field, Catherine E Lang, Jessica Barth, Carey L Holleran, Jeff D Konrad, Marghuretta D Bland

Open Access Publications

While the promise of wearable sensor technology to transform physical rehabilitation has been around for a number of years, the reality is that wearable sensor technology for the measurement of human movement has remained largely confined to rehabilitation research labs with limited ventures into clinical practice. The purposes of this paper are to: (1) discuss the major barriers in clinical practice and available wearable sensing technology; (2) propose benchmarks for wearable device systems that would make it feasible to implement them in clinical practice across the world and (3) evaluate a current wearable device system against the benchmarks as an …

Electrospinning Piezoelectric Fibers For Biocompatible Devices, Bahareh Azimi, Mario Milazzo, Andrea Lazzeri, Stefano Berrettini, M. Jasim Uddin, Zhao Qin, Markus J. Buehler, Serena Danti

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

The field of nanotechnology has been gaining great success due to its potential in developing new generations of nanoscale materials with unprecedented properties and enhanced biological responses. This is particularly exciting using nanofibers, as their mechanical and topographic characteristics can approach those found in naturally occurring biological materials. Electrospinning is a key technique to manufacture ultrafine fibers and fiber meshes with multifunctional features, such as piezoelectricity, to be available on a smaller length scale, thus comparable to subcellular scale, which makes their use increasingly appealing for biomedical applications. These include biocompatible fiber-based devices as smart scaffolds, biosensors, energy harvesters, and …

Dietary Nitrate And The Oral Microbiome In Obesity, Health And Exercise, Christian E. Behrens

All ETDs from UAB

Obesity ranks among the top growing health concerns worldwide. The prevalence of obesity at all life stages continues to rise with nearly 40% of adults and 35% of children/adolescents being affected. Equally troublesome is the increased risk for a number of comorbidities associated with obesity including cardiovascular disease, stroke, type 2 diabetes mellitus, and certain types of cancer. The successful treatment of obesity, particularly long-term, continues to prove challenging and is often met with limited success. This highlights the importance of continued investigation into alternative strategies that may reduce the incidence and severity of obesity and associated pathophysiologies. Regular physical …

A Cellulose-Based Biological Sensor For The Quantitative Determination Of Glucose And Glycated Hemoglobin (Hba1c), Gilberto Henao-Pabon

Open Access Theses & Dissertations

ABSTRACT

Importance: Diabetes is a common world-wide disease characterized by insulin resistance and as result there is an increased risk of cardiovascular disease and other metabolic abnormalities, that contribute to irreversible end-organ damage. The cause of diabetes is multifactorial and includes genetic, inflammatory and environmental factors plus lifestyle issues. Because in diabetes there are high levels of glucose and glycated hemoglobin, these molecules are used in clinical settings for the acute and chronic management of diabetic patients.

Objectives: a. To design and build an electrochemical biological sensor using the enzyme Glucose Oxidase (GOX) to detect glucose in biological fluids.

b. …

The In Vitro Cytotoxic, Genotoxic, And Oxidative Damage Potentials Of The Oral Artificialsweetener Aspartame On Cultured Human Blood Cells, Kenan Çadirci, Özlem Özdemi̇r Tozlu, Hasan Türkez, Adi̇l Mardi̇noğlu

Turkish Journal of Medical Sciences

Background/aim: Aspartame (APM, L-aspartyl-L-phenylalanine methylester) is a low-calorie, nonsaccharide artificial sweetener widely used in foods and beverages. When metabolized by the body, APM is broken down into aspartic acid, phenylalanine amino acids, and a third substance, methanol. Since the amino acid phenylalanine serves as a neurotransmitter building block affecting the brain, and methanol is converted into toxic formaldehyde, APM has deleterious effects on the body and brain. Thus, its safety and, toxicity have been the subjects of concern ever since it was first discovered. Although many studies have been performed on it, due to the presence of conflicting data in …

Light And Scanning Electron Microscopic Examination Of The Saanen Goat Heart, Sedef Selvi̇ler Si̇zer, Yonca Beti̇l Kabak, Murat Kabak

Turkish Journal of Veterinary & Animal Sciences

It is important to know the morphological structure of the heart, which is a vital organ of the body, in detail. For this reason, we aimed to examine the morphological structure of the Saanen goat heart using light and scanning electron microscopy (SEM). A total of thirteen Saanen goat hearts were used in the study. To demonstrate the histological structure of the heart, samples taken from 9 hearts were fixed in 10% formaldehyde solution and blocked in paraffin after routine histological procedures. Histological staining was performed on the sections taken from the blocks. Four hearts were fixed in a 2.5% …

On Body Mass Index Analysis From Human Visual Appearance, Min Jiang

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the past few decades, overweight and obesity are spreading widely like an epidemic. Generally, a person is considered overweight by body mass index (BMI). In addition to a body fat measurement, BMI is also a risk factor for many diseases, such as cardiovascular diseases, cancers and diabetes, etc. Therefore, BMI is important for personal health monitoring and medical research. Currently, BMI is measured in person with special devices. It is an urgent demand to explore conveniently preventive tools. This work investigates the feasibility of analyzing BMI from human visual appearances, including 2-dimensional (2D)/3-dimensional (3D) body and face data.

Motivated …