Digital Commons Network^™

Examining The Use Of Mhealth Technology For Weight Management: A Hybrid Effectiveness-Implementation Trial In Family Medicine, Laurel A. Brabson M.S.

Graduate Theses, Dissertations, and Problem Reports (ETD)

Overweight and obesity are prevalent and problematic conditions in the United States and worldwide, and effective weight management interventions are underutilized. Efforts to improve weight management practices have focused almost exclusively on changing physician behavior, without considering the larger healthcare context or the reciprocal patient-physician relationship. The current study explored the possibility of leveraging technology to improve the implementation of weight management clinical practice guidelines and increase patient-physician weight management discussions. 100 patients of five family medicine physicians were randomly assigned to either complete a weight management mobile application (app) prior to their primary care visit (app condition), or to …

Breaking The Chain: Evaluating The Links Between Opioid Use Disorder, Overdose, And Suicide, Amanda Nicole Stover Mph

Graduate Theses, Dissertations, and Problem Reports (ETD)

Previous research has estimated that 20–30% of individuals with opioid use disorder (OUD) have a history of both suicide attempt and unintentional opioid overdose. In 2018, more than 1.9 million adults 18 years and older had an OUD; while 1.4 million adults attempted suicide that same year (SAMHSA, 2019). The key to understanding this relationship is examining behaviors that precede these potentially fatal behaviors. One such precursory behavior is self-injury. Self-injurious behaviors (SIB) are one of the most important risk factors for future suicide (Cavanagh et al.,2003). This study has three primary objectives. The first is to conduct a systematic …

Predictors Of Self-Control During Emerging Adulthood: The Roles Of Implicit Beliefs And Early Risk, Katy L. Delong

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study explored how early adverse experiences (i.e., low socioeconomic status, household chaos, attachment insecurity) and implicit beliefs about self-control (i.e., whether self-control is a limited or nonlimited resource) were associated with trait and momentary self-control in a sample of college students. As the first study to explore these factors together, individuals’ implicit beliefs were tested as a moderator and meditator of the association between early risk and self-control. Participants (N = 214) first completed a baseline survey with the main predictors and trait self-control, followed by one week of experience sampling to assess momentary self-control, or success resisting …

The Immunological Response To Chronic Stress In Obese Mice, Matthew Corey Parsley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Obesity and psychological stress are major risk factors for cardiovascular disease and have a positive correlation with vascular dysfunction. This functional deficit has been linked to a pro-inflammatory milieu, exacerbated by an upregulation of pro-inflammatory cytokines. Febuxostat, a xanthine oxidase inhibitor, has been shown to rescue vascular impairment in these models. The purpose of this study was to examine the individual and combined effects of obesity and chronic stress on neuroimmune cell populations, and assess if febuxostat is able mediate immune alterations.

Male mice (n=48) were assigned into either normal chow (lean) and high-fat diet (obese) groups. The lean animals …

Innovative Approaches To 3d Gis Modeling For Volumetric And Geoprocessing Applications In Subsurface Infrastructures In A Virtual Immersive Environment, Pragya Srivastava

Graduate Theses, Dissertations, and Problem Reports (ETD)

As subsurface features remain largely ‘out of sight, out of mind’, this has led to challenges when dealing with underground space and infrastructures and especially so for those working in GIS. Since subsurface infrastructure plays a major role in supporting the needs of modern society, groups such as city planners and utility companies and decision makers are looking for an ‘holistic’ approach where the sustainable use of underground space is as important as above ground space. For such planning and management, it is crucial to examine subsurface data in a form that is amenable to 3D mapping and that can …

Implications Of Variability Of Electromyographic Measurements For Assessing Localized Muscle Fatigue, Hamad Nasser Alasim

Graduate Theses, Dissertations, and Problem Reports (ETD)

The impact of work-related musculoskeletal disorders (WMSDs) is enormous due to a combination of direct and indirect costs associated with healthcare, lost workdays and human suffering. Because of the established relationship between Localized Muscle Fatigue (LMF) development and WMSDs, and in order to reduce and/or prevent WMSDs in workplaces, different fatigue assessment methods have been developed. Surface Electromyography (SEMG) is a commonly used LMF assessment technique. The SEMG signals are typically analyzed in time and frequency domains to predict LMF based on a relative change with respect to initial, or under no-fatigue conditions. Quantifying such change, however, relies on the …

The Effects Of Intrinsic Foot Muscle Strengthening On Foot Posture, Balance, And Agility In Ice Hockey Players, Rebecca Eve Veltrie

Graduate Theses, Dissertations, and Problem Reports (ETD)

Context: Research has shown that intrinsic foot muscle strengthening over a 4-week period is beneficial for improvements in dynamic postural control, function, stability and foot posture. Ice hockey is a sport that requires immense levels of balance, stability and performance on the lateral aspect of the skate. With research lacking on the impact of intrinsic foot muscle strengthening on ice hockey athletes’ balance, foot posture and performance, implementation of such a program may be beneficial for ice hockey players. Objective: The purpose of this study was to explore the effects of foot intrinsic muscle strengthening versus a traditional …

Prescribing The Profession: Representations Of Medical Professionalization Debates In American Literary Forms, 1830-1940, Jeffrey Wayne Yeager

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation traces the debates concerning the professionalization of medicine in America across the 19^th- and well into the 20^th-century and explores how the debates concerning professionalization in any given moment affected popular literary forms. Using Fredric Jameson’s The Political Unconscious as its theoretical framework, this dissertation’s chapters on the gothic, realism, naturalism, and satire trace each mode’s dominant hegemonic position on this issue while showcasing dissenting voices across this century-long discourse. This project’s methodology is centered in the New Historicism. Unlike other projects before it, this dissertation focuses primarily on the historical problem of state …

Three Essays On The Effect Of Pain-Of-Payment On Consumers' Financial Decisions, Farnoush Reshadi

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the past few years, we have witnessed a growing level of consumer debt. Although being in debt increases consumers’ stress and reduces their financial well-being, many consumers still take on high levels of debt and hold on to it even when they have financial resources to pay off the debt. Thus, it is of utmost importance to study factors that may influence consumers’ debt repayment. In this dissertation, I study consumers’ debt repayment behavior through the lens of the double-entry mental accounting theory (Prelec and Loewenstein 1998). This theory argues that consumers’ debt repayment behaviors are driven by pain-of-payment--negative …

Tree Growth And Water Use Efficiency During The Twentieth Century: From Global Trends To Local Drivers, Justin Michael Mathias

Graduate Theses, Dissertations, and Problem Reports (ETD)

The frequency and severity of extreme environmental conditions will continue to increase under global environmental change. How terrestrial plants respond to prolonged, and often novel environmental stressors, will have profound impacts on, and feedbacks with, the Earth climate system at local to continental scales. Central to these feedbacks are plant stomata, actively regulated pores on the leaves of plants that act as a control valve over the fluxes of carbon dioxide (CO₂) into the leaf during photosynthesis and water vapor (H₂O) out of the leaf during transpiration. Importantly, changes in stomatal aperture do not affect the …

Paper-Based Point-Of-Care Tools For Blood Testing, Xuefei Gao

Graduate Theses, Dissertations, and Problem Reports (ETD)

Early detection of malignant disease is crucial for timely diagnosis and effective medical intervention, which significantly increases survival rates and reduce financial burden on patients. Biomarkers are becoming increasingly important in detection of malignant diseases, because they can be employed for indicating diseases, predicting risks and monitoring the progression of diseases. In addition, biomarkers show up at early stages of diseases in human tissues and fluids (e.g., blood, urine and saliva), which shows great promise for early disease detection. In this dissertation, paper-based lateral flow strips (PLFSs) have been developed for the detection of disease biomarkers, including protein biomarkers and …

Retrospective Evaluation Of The Changes In The Nasal And Pharyngeal Airway Volume After Miniscrew Assisted Rapid Palatal Expansion (Marpe) Appliance, Joanna Song

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background and Objectives: A transverse deficiency of the maxilla is a pervasive skeletal problem that can affect almost a quarter of the primary dentition population. The interesting relationship between rapid maxillary expansion (RME) and its effects on the surrounding airway is not well described in the literature. For today’s contemporary orthodontist, there are a variety of rapid palatal expanders (RPE) and expansion protocols to prescribe for patient treatment. Of late, the miniscrew-assisted RPE (MARPE) has been receiving attention by clinicians because of its increased orthopedic effects when compared to conventional RPE while avoiding the surgical procedure needed with SARPE. …

Rational Drilling Control Parameters To Reduce Respirable Dust During Roof Bolting Operations, Hua Jiang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Roof bolting has been the primary means to improve mine safety in the aspect of preventing different types of roof falls in underground mines. However, based on the published researches, underground roof bolting operators exhibit a continued risk for overexposure to high levels of respirable coal and crystalline silica dust from the roof drilling operation. Inhaling these dust can cause coal workers’ pneumoconiosis (CWP), also known as black lung. Another job-related lung disease silicosis, a disabling and even fatal and irreversible illness, could be developed through overexposure to quartz-laden dust. A recent NIOSH research shows that the quartz content in …

Hepatitis B In At-Risk Groups: Three Studies To Guide Education, Testing, And Vaccination Efforts In West Virginia, Stacy Tressler

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background and Objectives: For over a decade, West Virginia’s (WV) rate of acute hepatitis B has been the highest in the United States (US). In 2017, WV’s rate was 11.7 per 100,000 population, almost 12 times higher than the national rate. The increase in acute hepatitis B cases is largely due to substance misuse, including injection drug use (IDU). Hepatitis B is a vaccine preventable disease yet many at-risk adults remain unvaccinated and susceptible to infection. The objectives of our studies are to 1) describe yearly changes in acute hepatitis B incidence in WV and assess county-level impact of the …

Clear Aligner Therapy Vs. Traditional Brackets On Smile Arc, Sarah Elizabeth Larue

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background and Objectives: More so than ever, the public is becoming exceedingly aware of esthetics, and will evaluate their treatment outcome based upon the improvement to their smile and overall enhancement of their facial appearance. Smile arc is considered to be a key component of facial esthetics. Literature has demonstrated that orthodontic treatment mechanics utilizing traditional brackets and wires can cause flattening of the smile arc and that smiles with flatter arcs are judged to be less attractive. The aim of this study was to determine whether clear aligner therapy can help to preserve or improve the smile arc …

Adolescents’ Interpretations Of Parental Psychological Control: The Role Of Beliefs And Disapproval On Problematic Outcomes, Katelyn F. Romm

Graduate Theses, Dissertations, and Problem Reports (ETD)

Parental psychological control has consistently been found to be associated with problematic outcomes among adolescents, including substance use (Galambos, Barker, & Almeida, 2003), risky cyber behaviors (Li, Li, & Newman, 2013), problematic eating behaviors (Soenens et al., 2008), and depressive symptoms (Romm & Metzger, 2018). However, few studies have examined how adolescents reason about and react to psychological control. Recent research has suggested that adolescents vary in their beliefs about parental motivations for using psychological control, as well as their level of disapproval of psychological control (Camras et al., 2012; Kakihara & Tilton-Weaver, 2009). These cognitive factors (i.e., beliefs about …

Impact Of Sire Selection And Breed On Parasite Resistance In Sheep, Andrew Ryan Weaver

Graduate Theses, Dissertations, and Problem Reports (ETD)

Selection within and among breeds are strategies to mitigate the impact of parasitism given failing chemotherapeutics. While Texels have improved marketability compared to other parasite-resistant breeds, the mechanism by which Texels reduce fecal egg count (FEC) is unclear. The immune response to Haemonchus contortus (Hc) was compared in Texel, parasite-resistant St. Croix, and parasite-susceptible Suffolk sheep. Adult worms exposed to St. Croix- and Texel-derived peripheral blood mononuclear cells and serum in vitro had greater binding around the reproductive structures than Suffolk and worm egg release tended to be affected by breed (P = 0.09). Resistance in Texels …

The Exploration Of Nanotoxicological Copper And Interspecific Saccharomyces Hybrids, Matthew Joseph Winans Phd

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nanotechnology takes advantage of cellular biology’s natural nanoscale operations by interacting with biomolecules differently than soluble or bulk materials, often altering normal cellular processes such as metabolism or growth. To gain a better understanding of how copper nanoparticles hybridized on cellulose fibers called carboxymethyl cellulose (CMC) affected growth of Saccharomyces cerevisiae, the mechanisms of toxicity were explored. Multiple methodologies covering genetics, proteomics, metallomics, and metabolomics were used during this investigation. The work that lead to this dissertation discovered that these cellulosic copper nanoparticles had a unique toxicity compared to copper. Further investigation suggested a possible ionic or molecular mimicry …

Changing Dynamics Of Opioid Overdoses In West Virginia And Impact Of Medication For Opioid Use Disorder And Recurrence Of Overdose On Reducing Mortality Among West Virginia Medicaid Beneficiaries, Zheng Dai

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background

With increasing number of opioid overdoses in West Virginia (WV) in recent years and limited number of people receiving treatment, the dissertation study aims to better understand fatal overdose problems in WV and the impact of medication for opioid use disorder (MOUD) in preventing overdose deaths.

Method

WV drug-related deaths from 2005 to 2018 was used to describe the involvement of fentanyl and FAs. WV Medicaid claim data was analyzed to describe the recurrent opioid overdose and the changes in receipt of MOUD. Further, a Medicaid opioid overdose cohort was created to evaluate the effect of occurrence of recurrent …

Essays On The Political Economy Of Governance, Yang Zhou

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation studies the governance structure and its economic impacts in the Chinese context. Specifically, I use a public choice framework to analyze how institutions influence economic and political activities of both public officials and private sectors. Chapter 1 employs the synthetic control method to investigate the effects of institutions to regional economic development. Chongqing Municipality, a province-level region in China, had a unique leader from late 2007 to early 2012 who conducted red ideology movements and legal intervention. The empirical results reveal that although the economic policies promoted the Chongqing economy, the Maoist political policies partially undermined its economic …

Effects Of Appalachian Culture And Pregnancy Status On Pain-Related Fear, Cecelia Irene Nelson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fear of pain during pregnancy is an understudied phenomenon with important implications for prenatal and postpartum functioning. The aim of the current study was to understand the role of pregnancy and culture on pain-related fear in Appalachia. Archival datasets, and a new sample of women recruited via Amazon’s Mechanical Turk, were sources of data. Participants completed the Fear of Pain Questionnaire-9 and responded to demographic questions in order to ascertain whether they were pregnant at the time of the study as well as the number and nature of prior pregnancies. In support of hypotheses, results indicated that pregnant women reported …

Time-Dependent Reliability Framework For Durability Design Of Frp Composites, Rajneesh Kumar Bharil

Graduate Theses, Dissertations, and Problem Reports (ETD)

The life-cycle performance, durability, and aging characteristics of Fiber Reinforced Polymer (FRP or Structural Composites) have been of keen interest to the engineers engaged in the FRP design, construction, and manufacturing. Unlike conventional construction materials such as steel and concrete, the design guidelines to account for the aging of FRP are somewhat scattered or not available in an approved or consistent format. Loss of strength over time or aging of any structural material should be of concern to engineers as the in-service lifespan of many engineering structures is expected to exceed 100 years. Use of durability strength-reduction factors or factors …

Using The Social Ecological Model To Build A Path Analysis Model Of Physical Activity In A Sample Of Active Us College Students, Jonathan J. Stewart

Graduate Theses, Dissertations, and Problem Reports (ETD)

Objective: To examine how achievement goal orientation, perceived barriers and benefits, self-efficacy, on-campus residence, transportation, and binge drinking impact physical activity. Participants: Five hundred and twenty (70.23% female) college students participated in the study during Fall 2014. Methods: Students completed an online questionnaire that measured environmental and psychosocial factors, and physical activity behaviors. Results: A path analysis revealed that self-efficacy, episodes of binge drinking, use of active transportation, and use of public transportation all had significant direct effects on physical activity. Meanwhile, perceived barriers had a significant negative direct effect on physical activity. Conclusion: Results indicate that both environmental and …

Two Approaches To Analyzing Institutions’ Spending Responses To Campus Sexual Assault, Amanda M. Rose

Graduate Theses, Dissertations, and Problem Reports (ETD)

Despite occupying a growing portion in contemporary U.S. higher education institutions’ annual budgets, empirical research on sexual assault costs is limited. The purpose of this study is to look at whether incidences of sexual violence on campus are associated with increased costs in policies and programs geared toward prevention of these crimes. Informing the analysis is a theoretical framework consisting of the revenue theory of costs and positional arms race theory. This study examines data from both IPEDS and the U.S. Department of Education Crime and Safety website over a ten year period, 2006-2015, for a set of over 2,300 …

The Role Of Flavors In Electronic Cigarette Abuse Liability In Tobacco-Naïve Young Adults, Ilana Haliwa

Graduate Theses, Dissertations, and Problem Reports (ETD)

A primary public health concern associated with the use of electronic cigarettes (ECIGS) has been the risk of product initiation by vulnerable young adults who are largely naïve to tobacco. The use of ECIGs among such individuals may be influenced by the wide variety of sweet flavored liquids available for purchase. Previous work suggests that one flavor, menthol, increases the likelihood of abuse of cigarettes. Thus, the United States Food and Drug Administration has requested input from the research community regarding the abuse liability of flavored ECIGs in order to inform future product regulation. Using a double-blind, within-subject study design, …

Experimental, Computational And Analytical Studies Towards A Predictive Scenario For A Burning Accident, Furkan Kodakoglu

Graduate Theses, Dissertations, and Problem Reports (ETD)

Historically, accidental gas and dust explosions constitute one of the major hazards to both personnel and equipment in the process industries. The current knowledgebase on such explosions does not provide an acceptable level of risk. Therefore, novel preventive mining/fire safety strategies, based on a rigorous predictive scenario for burning accidents, are critically needed. The present dissertation is devoted to such a predictive scenario, with a particular focus on the flame and pressure evolutions in explosions encountered in an enclosure with or without obstructions. The experimental component of this dissertation comprises a series of experiments on explosion venting. Specifically, the influence …

Role Of Ciliary Proteins Adp Ribosylation Factor Like Gtpase 13b (Arl13b) And Bardet-Biedl Syndrome-8 (Bbs8) In Photoreceptor Outer Segment Morphogenesis, Maintenance, And Viability, Tanya L. Dilan

Graduate Theses, Dissertations, and Problem Reports (ETD)

Photoreceptor neurons are modified primary cilia with an extended ciliary compartment known as the outer segment (OS). The mechanisms behind the elaboration of photoreceptor cilia, OS morphogenesis, and maintenance remain poorly understood. In this work, we focused on dissecting the role of two ciliary proteins, the small GTPase ADP-ribosylation factor-like GTPase 13B (ARL13B) and Bardet-Biedl Syndrome-8 (BBS8) in the context of photoreceptor biology. Both BBS8 and ARL13B are linked to defects in ciliogenesis (cilia development) and Retinitis Pigmentosa (vision loss). ARL13B is implicated in regulating ciliary length, and BBS8 is part of the Bardet-Biedl Syndrome complex (BBSome); the BBSome is …

An In-Depth Investigation Of The Effects Of Work-Related Factors On The Development Of Knee Musculoskeletal Disorders Among Construction Roofers, Amrita Dutta

Graduate Theses, Dissertations, and Problem Reports (ETD)

Construction roofers have the uppermost likelihood of developing knee musculoskeletal disorders (MSDs). Roofers spend more than 75% of their total working time being restricted to awkward kneeling postures and repetitive motions in a sloped roof setting. However, the combined effect of knee-straining posture, roof slope and their association to knee MSDs among roofers are still unknown. This dissertation aimed to provide empirical evidence of the effects of two roofing work-related factors namely, roof slope and kneeling working posture, on the development of knee MSDs among construction roofers. These two factors were assessed as potential to increase knee MSD risks in …

Resilience In The Mountains: Exploring The Labor And Motives Of Food-Caregiver Women Repairing Broken Food Systems In West Virginia Communities, Heidi Lynn Gum

Graduate Theses, Dissertations, and Problem Reports (ETD)

Over the past four years the Food Justice Lab, now housed within the Center for Resilient Communities at West Virginia University, hosted a series of food access planning workshops across the state of West Virginia. Mobilizing more than 200 participants, the Nourishing Networks workshop training program was designed to build grassroots capacity for food system change. Eighty-percent of workshop participants were women and dialogues recorded at these events revealed how women are disproportionately impacted by food insecurity and disproportionately labor to repair a broken food system. Women in West Virginia are not only growing food, feeding their families, selling it …

Stable Aggregate Dynamics And Carbon Storage In Acidified Forest Soils: Influence Of Atmospheric Deposition And Conifer Conversion At The Fernow Experimental Forest, J E. Kemner

Graduate Theses, Dissertations, and Problem Reports (ETD)

This research explored effects of ecosystem change from increased atmospheric nitrogen (N) deposition and stand conversion from mixed-species hardwood to Norway spruce in three experimental watersheds at the Fernow Experimental Forest (FEF). I measured soil aggregation and organic matter (OM) content to investigate the influence of forest fertilization in Watershed 3 (WS3), a hardwood forest receiving (NH₄)₂SO₄ fertilizer, versus Watershed 7 (WS7), a natural hardwood forest. I compared WS7 to Watershed 6 (WS6), a converted Norway spruce (Picea abies) monoculture. I quantified WS6 and WS7 C and N ecosystem pools, including vegetation biomass, …