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2020

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Improving Firefighter Tenability During Entrapment And Burnover: An Analysis Of Vehicle Protection Systems, Greg Penney, Daryoush Habibi, Marcus Cattani Jan 2020

Improving Firefighter Tenability During Entrapment And Burnover: An Analysis Of Vehicle Protection Systems, Greg Penney, Daryoush Habibi, Marcus Cattani

Research outputs 2014 to 2021

When attempting to suppress severe wildfire the possibility for firefighting crews to be overrun by wildfire, known as entrapment and burnover, remains a catastrophic and all too common occurrence. While improvements have been made to vehicle protection systems to increase the safety of firefighters caught in burnover, the potential effectiveness of these systems remains limited. This study involved systematic analysis of 62 historical entrapment and burnover reports from the USA, Australian and New Zealand from 1978 to 2020 (Phase 1), and 135 simulated wildfires encompassing the 99th percentile of Australian fire weather conditions, fuel structures and terrain (Phase 2). Analysis …


Rural Dialysis Nurses’ Experiences With Challenging Patients: A Thematic Qualitative Analysis, Alycia Jacob, Caroline Vafeas, Laurita Stoneman, Elisabeth Jacob Jan 2020

Rural Dialysis Nurses’ Experiences With Challenging Patients: A Thematic Qualitative Analysis, Alycia Jacob, Caroline Vafeas, Laurita Stoneman, Elisabeth Jacob

Research outputs 2014 to 2021

Background: This study explored the experience of nurses encountering challenging patient behaviour while working at a rural hospital-based haemodialysis unit.

Methods: Focus groups were conducted with haemodialysis nurses at a rural hospital. Five participants across two focus groups were asked questions regarding their experiences of challenging patients, including impacts that the experiences may have had on their ongoing professional practice. Transcripts of the focus groups were analysed thematically.

Findings: Three themes arose from the focus group discussion – experiencing challenging behaviour, long-term relationships with patients, and nursing professionalism. Participants described challenges arising when caring for patients who were aggressive, did …


Reviewing The Current Methods Of Assessing Hydration In Athletes, Oliver R. Barley, Dale W. Chapman, Chris R. Abbiss Jan 2020

Reviewing The Current Methods Of Assessing Hydration In Athletes, Oliver R. Barley, Dale W. Chapman, Chris R. Abbiss

Research outputs 2014 to 2021

Background

Despite a substantial body of research, no clear best practice guidelines exist for the assessment of hydration in athletes. Body water is stored in and shifted between different sites throughout the body complicating hydration assessment. This review seeks to highlight the unique strengths and limitations of various hydration assessment methods described in the literature as well as providing best practice guidelines.

Main body

There is a plethora of methods that range in validity and reliability, including complicated and invasive methods (i.e. neutron activation analysis and stable isotope dilution), to moderately invasive blood, urine and salivary variables, progressing to non-invasive …


Can Exercise Adaptations Be Maintained In Men With Prostate Cancer Following Supervised Programmes? Implications To The Covid-19 Landscape Of Urology And Clinical Exercise, Pedro Lopez, Dennis R. Taaffe, Robert U. Newton, Nigel Spry, Tom Shannon, Mark Frydenberg, Fred Saad, Daniel A. Galvão Jan 2020

Can Exercise Adaptations Be Maintained In Men With Prostate Cancer Following Supervised Programmes? Implications To The Covid-19 Landscape Of Urology And Clinical Exercise, Pedro Lopez, Dennis R. Taaffe, Robert U. Newton, Nigel Spry, Tom Shannon, Mark Frydenberg, Fred Saad, Daniel A. Galvão

Research outputs 2014 to 2021

© 2020 The Author(s) In this brief correspondence, we evaluate the potential impact of pivoting from face-to-face supervised to unsupervised home-based exercise programmes to contextualise the coronavirus disease 2019 (COVID-19) pandemic in prostate cancer patients. A meta-analysis was undertaken in fatigue, quality of life, and lean and fat mass outcomes in the four studies included. Our analysis indicates that unsupervised home-based exercise maintains patient-reported outcomes, except for fat mass. In summary, changing to unsupervised exercise is unlikely to provide further benefits on patient-reported and body composition outcomes, but may help maintain initial gains during physical distancing restrictions. Patient summary: We …


Implementation, Mechanisms Of Impact And Key Contextual Factors Involved In Outcomes Of The Modification Of Diet, Exercise And Lifestyle (Model) Randomised Controlled Trial In Australian Adults: Protocol For A Mixed-Method Process Evaluation, Reindolf Anokye, Simone Radavelli-Bagatini, Catherine P. Bondonno, Marc Sim, Lauren C. Blekkenhorst, Emma Connolly, Nicola P. Bondonno, John T. Schousboe, Richard Woodman, Kun Zhu, Pawel Zhu, Ben Jackson, James Dimmock, Markus P. Schlaich, Kay L. Cox, Douglas P. Kiel, Wai H. Lim, Amanda Devine, Peter L. Thompson, Jenny Gianoudis, Belinda De Ross, Robin M. Daly, Jonathan M. Hodgson, Joshua Lewis, Mandy Stanley Jan 2020

Implementation, Mechanisms Of Impact And Key Contextual Factors Involved In Outcomes Of The Modification Of Diet, Exercise And Lifestyle (Model) Randomised Controlled Trial In Australian Adults: Protocol For A Mixed-Method Process Evaluation, Reindolf Anokye, Simone Radavelli-Bagatini, Catherine P. Bondonno, Marc Sim, Lauren C. Blekkenhorst, Emma Connolly, Nicola P. Bondonno, John T. Schousboe, Richard Woodman, Kun Zhu, Pawel Zhu, Ben Jackson, James Dimmock, Markus P. Schlaich, Kay L. Cox, Douglas P. Kiel, Wai H. Lim, Amanda Devine, Peter L. Thompson, Jenny Gianoudis, Belinda De Ross, Robin M. Daly, Jonathan M. Hodgson, Joshua Lewis, Mandy Stanley

Research outputs 2014 to 2021

Introduction

The Modification of Diet, Exercise and Lifestyle (MODEL) study aims to examine the impact of providing visualisation and pictorial representation of advanced structural vascular disease (abdominal aortic calcification), on ‘healthful’ improvements to diet and lifestyle. This paper reports the protocol for the process evaluation for the MODEL study.

Methods and analysis

The overall aim of the process evaluation is to understand the processes that took place during participation in the MODEL study trial and which elements were effective or ineffective for influencing ‘healthful’ behavioural change, and possible ways of improvement to inform wider implementation strategies. A mixed-method approach will …


Stopping Targeted Therapy For Complete Responders In Advanced Braf Mutant Melanoma, Lydia Warburton, Tarek M. Meniawy, Leslie Calapre, Michelle Pereira, Ashleigh Mcevoy, Mel Ziman, Elin Gray, Michael Millward Jan 2020

Stopping Targeted Therapy For Complete Responders In Advanced Braf Mutant Melanoma, Lydia Warburton, Tarek M. Meniawy, Leslie Calapre, Michelle Pereira, Ashleigh Mcevoy, Mel Ziman, Elin Gray, Michael Millward

Research outputs 2014 to 2021

BRAF inhibitors revolutionised the management of melanoma patients and although resistance occurs, there is a subgroup of patients who maintain durable disease control. For those cases with durable complete response (CR) it is not clear whether it is safe to cease therapy. Here we identified 13 patients treated with BRAF +/− MEK inhibitors, who cease therapy after prolonged CR (median = 34 months, range 20–74). Recurrence was observed in 3/13 (23%) patients. In the remaining 10 patients with sustained CR off therapy, the median follow up after discontinuation was 19 months (range 8–36). We retrospectively measured ctDNA levels using droplet …


Using A Respectful Approach To Child-Centred Healthcare (Reach) In A Paediatric Clinical Trial: A Feasibility Study, Analise Nicholl, Kate Evelegh, Kane Evan Deering, Kate Russell, David Lawrence, Philippa Lyons-Wall, Therese O'Sullivan Jan 2020

Using A Respectful Approach To Child-Centred Healthcare (Reach) In A Paediatric Clinical Trial: A Feasibility Study, Analise Nicholl, Kate Evelegh, Kane Evan Deering, Kate Russell, David Lawrence, Philippa Lyons-Wall, Therese O'Sullivan

Research outputs 2014 to 2021

Background

There is a growing momentum in paediatric ethics to develop respectful research and healthcare protocols. We developed, tested and refined our ‘Respectful Approach to Child-centred Healthcare’ (ReACH), to underpin respectful participant interactions in a clinical trial.

Objective

To determine whether a ReACH-based approach is acceptable to children and parents, and effective in obtaining compliance with common healthcare assessments in a clinical trial of healthy 4-6-year-old children.

Methods

ReACH-based child assessments were evaluated at two baseline clinics and one post-intervention, using mixed methods. Children (n = 49; 46.9% female; mean age = 5.24±0.88 years at baseline) and their parents provided …


“Fallen Through The Cracks”: Teachers’ Perceptions Of Barriers Faced By Struggling Literacy Learners In Secondary School, Margaret K. Merga Jan 2020

“Fallen Through The Cracks”: Teachers’ Perceptions Of Barriers Faced By Struggling Literacy Learners In Secondary School, Margaret K. Merga

Research outputs 2014 to 2021

© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Struggling literacy learners are typically low achievers with poor engagement in literacy learning, and the gap between struggling and capable students widens as children move through the years of schooling. Literacy research and interventions for struggling literacy learners typically focus on the primary school years. The 2019 Supporting Struggling Secondary Literacy Learners mixed-methods project collected qualitative data on teacher perceptions of the barriers experienced by their struggling literacy learners in Australian mainstream secondary English classrooms. Recurring barriers included literacy skill gaps and English as an …


Nursing And Midwifery Students' Experiences And Perception Of Their Clinical Learning Environment In Malawi: A Mixed-Method Study, B. C. Mbakaya, F. W. Kalembo, Maggie Zgambo, A. Konyani, F. Lungu, B. Tveit, A. Kaasen, M. Simango, T. Bvumbwe Jan 2020

Nursing And Midwifery Students' Experiences And Perception Of Their Clinical Learning Environment In Malawi: A Mixed-Method Study, B. C. Mbakaya, F. W. Kalembo, Maggie Zgambo, A. Konyani, F. Lungu, B. Tveit, A. Kaasen, M. Simango, T. Bvumbwe

Research outputs 2014 to 2021

© 2020 The Author(s). Background: The clinical learning environment is an important part of the nursing and midwifery training as it helps students to integrate theory into clinical practice. However, not all clinical learning environments foster positive learning. This study aimed to assess the student nurses and midwives' experiences and perception of the clinical learning environment in Malawi. Methods: A concurrent triangulation mixed methods research design was used to collect data from nursing and midwifery students. Quantitative data were collected using a Clinical Learning Environment Inventory, while qualitative data were collected using focus group discussions. The Clinical Learning Environment Inventory …


We Have The Program, What Now? Development Of An Implementation Plan To Bridge The Research-Practice Gap Prevalent In Exercise Oncology, Mary A. Kennedy, Sara Bayes, Robert U. Newton, Yvonne Zissiadis, Nigel A. Spry, Dennis R. Taaffe, Nicolas H. Hart, Michael Davis, Aileen Eiszele, Daniel A. Galvão Jan 2020

We Have The Program, What Now? Development Of An Implementation Plan To Bridge The Research-Practice Gap Prevalent In Exercise Oncology, Mary A. Kennedy, Sara Bayes, Robert U. Newton, Yvonne Zissiadis, Nigel A. Spry, Dennis R. Taaffe, Nicolas H. Hart, Michael Davis, Aileen Eiszele, Daniel A. Galvão

Research outputs 2014 to 2021

© 2020 The Author(s). Background: Exercise has emerged as a promising therapy for people with cancer. Novel programs have been developed to translate research into practice; however, implementation barriers have limited their success in part because successful translation of exercise oncology research into practice requires context-specific implementation plans. The aim of this study was to employ the implementation mapping protocol to develop an implementation plan to support programming of a co-located exercise clinic and cancer treatment center. Methods: The Implementation Mapping protocol, which consists of five specific iterative tasks, was used. A stakeholder advisory group advised throughout the process. Results: …


Keeping Patients With Cancer Exercising In The Age Of Covid-19, Robert U. Newton, Nicolas H. Hart, Tim Clay Jan 2020

Keeping Patients With Cancer Exercising In The Age Of Covid-19, Robert U. Newton, Nicolas H. Hart, Tim Clay

Research outputs 2014 to 2021

The novel 2019 coronavirus disease (COVID-19) pandemic is a global public health emergency. To date, physical distancing and good personal hygiene have been the only effective measures to limit spread. The pandemic has altered routine cancer care, including allied health and supportive care interventions. Clinicians must adapt and find ways to continue to deliver optimal patient care at this time. The prescription of exercise to people with cancer has been demonstrated to have meaningful benefits for both physical and mental health and quality of life, and may even enhance survival. Such exercise interventions provide the largest benefit to patients when …


Prevalence Of Attention-Deficit/Hyperactivity Disorder Among Primary School Children In Oforikrom, Ghana Based On The Disruptive Behavior Disorders Rating Scale, Reindolf Anokye, E. Acheampong, A. Edusei, I. Owusu, W. K. Mprah Jan 2020

Prevalence Of Attention-Deficit/Hyperactivity Disorder Among Primary School Children In Oforikrom, Ghana Based On The Disruptive Behavior Disorders Rating Scale, Reindolf Anokye, E. Acheampong, A. Edusei, I. Owusu, W. K. Mprah

Research outputs 2014 to 2021

OBJECTIVE: To determine the prevalence of attention-deficit/hyperactivity disorder (ADHD) among primary school children in Oforikrom, Kumasi, Ghana. METHODS: 10 of 35 primary schools in Oforikrom were readily available. Of 2000 children aged 5 to 13 years selected, 1540 (77%) of their parents/guardians consented to participate. Their parents/guardians and six teachers from each school were asked to complete the Disruptive Behavior Disorders Rating Scale to screen children for the presence of ADHD, oppositional defiant disorder, or conduct disorder. Children who displayed symptoms (pretty much or very much) in most related items as determined by parents and/or teachers were considered positive cases. …


Impact Of Commuting Mode On Obesity Among A Working Population In Beijing, China: Adjusting For Air Pollution, Yue Liu, Lixin Tao, Jie Zhang, Jia Liu, Haibin Li, Xiangtong Liu, Yanxia Luo, Jingbo Zhang, Wei Wang, Xiuhua Guo Jan 2020

Impact Of Commuting Mode On Obesity Among A Working Population In Beijing, China: Adjusting For Air Pollution, Yue Liu, Lixin Tao, Jie Zhang, Jia Liu, Haibin Li, Xiangtong Liu, Yanxia Luo, Jingbo Zhang, Wei Wang, Xiuhua Guo

Research outputs 2014 to 2021

© 2020 Liu et al. Background: Few studies have considered the interplay between commuting mode and air pollution on obesity. The aim of this study was to examine whether workplace air pollutants exposure modifying the associations between different commuting mode and obesity. Methods: A cross-sectional study of workers in Beijing was conducted in 2016. The study sample comprised 10,524 participants aged 18 to 65 years old. Outcomes were defined as overall obesity (BMI ≥ 28 kg/m2) and abdominal obesity (WC ≥ 85 cm in men and WC ≥ 80 cm in women). Commuting modes were divided into walking, cycling, bus, …


Deciding To Enrol In A Cancer Trial: A Systematic Review Of Qualitative Studies, Bianca Viljoen, Suzanne K. Chambers, Jeff Dunn, Nicholas Ralph, Sonja March Jan 2020

Deciding To Enrol In A Cancer Trial: A Systematic Review Of Qualitative Studies, Bianca Viljoen, Suzanne K. Chambers, Jeff Dunn, Nicholas Ralph, Sonja March

Research outputs 2014 to 2021

© 2020 Viljoen et al. Background: Clinical trials are essential for the advancement of cancer treatments; how-ever, participation by patients is suboptimal. Currently, there is a lack of synthesized qualitative review evidence on the patient experience of trial entry from which to further develop decision support. The aim of this review is to synthesise literature reporting experiences of participants when deciding to enrol in a cancer clinical trial in order to inform practice. Methods: A systematic review and meta-synthesis of qualitative studies were conducted to describe the experiences of adult cancer patients who decided to enrol in a clinical trial …


Copper Toxicity Links To Pathogenesis Of Alzheimer’S Disease And Therapeutics Approaches, Hafza Wajeeha Ejaz, Wei Wang, Minglin Lang Jan 2020

Copper Toxicity Links To Pathogenesis Of Alzheimer’S Disease And Therapeutics Approaches, Hafza Wajeeha Ejaz, Wei Wang, Minglin Lang

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Alzheimer’s disease (AD) is an irreversible, age-related progressive neurological disorder, and the most common type of dementia in aged people. Neuropathological lesions of AD are neurofibrillary tangles (NFTs), and senile plaques comprise the accumulated amyloid-beta (Aβ), loaded with metal ions including Cu, Fe, or Zn. Some reports have identified metal dyshomeostasis as a neurotoxic factor of AD, among which Cu ions seem to be a central cationic metal in the formation of plaque and soluble oligomers, and have an essential role in the AD pathology. Cu-Aβ complex catalyzes the generation of …


Understanding Factors That Enable And Inhibit Assessment Of Outcomes Of Competence Development, Andreas Wallo, Henrik Kock, Daniel Lundqvist, Alan Coetzer Jan 2020

Understanding Factors That Enable And Inhibit Assessment Of Outcomes Of Competence Development, Andreas Wallo, Henrik Kock, Daniel Lundqvist, Alan Coetzer

Research outputs 2014 to 2021

© The Author(s) 2020. Employee participation in formal and informal learning is essential for the economic viability and competitive advantage of organizations. Therefore, assessing outcomes of competence development activities is important. However, this domain of human resources (HR) practice is often neglected because of factors that are not well understood. Accordingly, this article addresses the question: What factors enable and inhibit HR professionals in assessing outcomes of competence development activities and initiatives? To answer this question, we conducted a review of articles that examine assessment of outcomes of competence development activities. The primary purpose of the review was to identify …


Do Schools And Alcohol Mix? Australian Parents' Perspectives, Conor Gilligan, Therese Shaw, Shelley Beatty, Laura Thomas, Karen Louise Lombardi, Robyn Susanne Johnston Jan 2020

Do Schools And Alcohol Mix? Australian Parents' Perspectives, Conor Gilligan, Therese Shaw, Shelley Beatty, Laura Thomas, Karen Louise Lombardi, Robyn Susanne Johnston

Research outputs 2014 to 2021

© 2020, Emerald Publishing Limited. Purpose: Alcohol use by adults at school events and alcohol promotion through school fundraising activities is common, but little is known about secondary school parents' attitudes towards these practices. Parental attitudes may influence principals' decision-making on this topic, particularly in jurisdictions where education department guidance is limited. This study explored parents' attitudes towards the consumption or promotion of alcohol in schools or at school events. Design/methodology/approach: Parents (n = 298) from five non-government secondary schools in Western Australia completed an online survey and provided responses relating to the promotion and availability of alcohol through their …


Psychological Symptoms In Chinese Nurses May Be Associated With Predisposition To Chronic Disease: A Cross-Sectional Study Of Suboptimal Health Status, Jinxiu Zhu, Wenjuan Ying, Li Zhang, Gangyi Peng, Weiju Chen, Enoch Odame Anto, Xueqing Wang, Nan Lu, Shanshan Gao, Guihai Wu, Jingyi Yan, Jianfeng Ye, Shenglin Wu, Chengzhi Yu, Minghui Yue, Xiru Huang, Nuo Xu, Pengxiang Ying, Yanhong Chen, Xuerui Tan, Wei Wang Jan 2020

Psychological Symptoms In Chinese Nurses May Be Associated With Predisposition To Chronic Disease: A Cross-Sectional Study Of Suboptimal Health Status, Jinxiu Zhu, Wenjuan Ying, Li Zhang, Gangyi Peng, Weiju Chen, Enoch Odame Anto, Xueqing Wang, Nan Lu, Shanshan Gao, Guihai Wu, Jingyi Yan, Jianfeng Ye, Shenglin Wu, Chengzhi Yu, Minghui Yue, Xiru Huang, Nuo Xu, Pengxiang Ying, Yanhong Chen, Xuerui Tan, Wei Wang

Research outputs 2014 to 2021

© 2020, The Author(s). Background: Suboptimal health status (SHS) is a reversible state between ideal health and illness and it can be effectively reversed by risk prediction, disease prevention, and personalized medicine under the global background of predictive, preventive, and personalized medicine (PPPM) concepts. More and more Chinese nurses have been troubled by psychological symptoms (PS). The correlation between PS and SHS is unclear in nurses. The purpose of current study is to investigate the prevalence of SHS and PS in Chinese nurses and the relationship between SHS and PS along with predisposing factors as well as to discuss the …


Divergence Of Safety And Security, David J. Brooks, Michael Coole Jan 2020

Divergence Of Safety And Security, David J. Brooks, Michael Coole

Research outputs 2014 to 2021

© 2020, The Author(s). Safety and security have similar goals, to provide social wellness through risk control. Such similarity has led to views of professional convergence; however, the professions of safety and security are distinct. Distinction arises from variances in concept definition, risk drivers, body of knowledge, and professional practice. This chapter explored the professional synergies and tensions between safety and security professionals, using task-related bodies of knowledge. Findings suggest that safety and security only have commonalities at the overarching abstract level. Common knowledge does exist with categories of risk management and control; however, differences are explicit. In safety, risk …


Co-Occurrence Across Time And Space Of Drug- And Cannabinoid- Exposure And Adverse Mental Health Outcomes In The National Survey Of Drug Use And Health: Combined Geotemporospatial And Causal Inference Analysis, Albert Stuart Reece, Gary Hulse Jan 2020

Co-Occurrence Across Time And Space Of Drug- And Cannabinoid- Exposure And Adverse Mental Health Outcomes In The National Survey Of Drug Use And Health: Combined Geotemporospatial And Causal Inference Analysis, Albert Stuart Reece, Gary Hulse

Research outputs 2014 to 2021

Background: Whilst many studies have linked increased drug and cannabis exposure to adverse mental health (MH) outcomes their effects on whole populations and geotemporospatial relationships are not well understood.

Methods

Ecological cohort study of National Survey of Drug Use and Health (NSDUH) geographically-linked substate-shapefiles 2010–2012 and 2014–2016 supplemented by five-year US American Community Survey. Drugs: cigarettes, alcohol abuse, last-month cannabis use and last-year cocaine use. MH: any mental illness, major depressive illness, serious mental illness and suicidal thinking. Data analysis: two-stage, geotemporospatial, robust generalized linear regression and causal inference methods in R.

Results

410,138 NSDUH respondents. Average response rate 76.7%. …


The Effects Of Yam Gruel On Lowering Fasted Blood Glucose In T2dm Rats, Xinjun Lin, Zongting Luo, Shuqin Pang, Carol Chunfeng Wang, Li Ge, Yanling Dai, Jian Zhou, Fang Chen, Xuepei Hong, Jiahui Zhang Jan 2020

The Effects Of Yam Gruel On Lowering Fasted Blood Glucose In T2dm Rats, Xinjun Lin, Zongting Luo, Shuqin Pang, Carol Chunfeng Wang, Li Ge, Yanling Dai, Jian Zhou, Fang Chen, Xuepei Hong, Jiahui Zhang

Research outputs 2014 to 2021

© 2020 Xinjun Lin et al., published by De Gruyter 2020. There is increasing evidence of the linkage between type 2 diabetes mellitus (T2DM) and gut microbiota. Based on our previous studies, we investigated the hypoglycemic mechanisms of yam gruel to provide a scientific basis for its popularization and application. Wistar rats were randomly divided into control and T2DM model groups. Rats in the model group were stimulated by a high-sugar/high-fat diet combined with an intraperitoneal injection of streptozotocin to induce T2DM. The T2DM rats were further subdivided randomly into three groups: (1) DM, (2) DM + yam gruel, and …


Biceps Brachii Muscle Hardness Assessed By A Push-In Meter In Comparison To Ultrasound Strain Elastography, Mitsuyoshi Murayama, Kazunori Nosaka, Takayuki Inami, Norihiro Shima, Tsugutake Yoneda Jan 2020

Biceps Brachii Muscle Hardness Assessed By A Push-In Meter In Comparison To Ultrasound Strain Elastography, Mitsuyoshi Murayama, Kazunori Nosaka, Takayuki Inami, Norihiro Shima, Tsugutake Yoneda

Research outputs 2014 to 2021

© 2020, The Author(s). This study investigated the relationship between push-in meter (PM) and ultrasound strain elastography (USE) for biceps brachii (BB) muscle hardness. BB hardness of 21 young men was assessed by PM and USE during rest and isometric contractions of six different intensities (15, 30, 45, 60, 75, 90% of maximal voluntary contraction: MVC) at 30°, 60° and 90° elbow flexion. Muscle hardness (E) was calculated from the force–displacement relationship in PM, and strain ratio (SR) between an acoustic coupler (elastic modulus: 22.6 kPa) and different regions of interest (ROIs) in BB was calculated and converted to Young’s …


Mapping Of Diabetes Susceptibility Loci In A Domestic Cat Breed With An Unusually High Incidence Of Diabetes Mellitus, Lois Balmer, Caroline Ann O’Leary, Marilyn Menotti-Raymond, Victor David, Stephen O’Brien, Belinda Penglis, Sher Hendrickson, Mia Reeves-Johnson, Susan Gottlieb, Linda Fleeman, Dianne Vankan, Jacquie Rand, Grant Morahan Jan 2020

Mapping Of Diabetes Susceptibility Loci In A Domestic Cat Breed With An Unusually High Incidence Of Diabetes Mellitus, Lois Balmer, Caroline Ann O’Leary, Marilyn Menotti-Raymond, Victor David, Stephen O’Brien, Belinda Penglis, Sher Hendrickson, Mia Reeves-Johnson, Susan Gottlieb, Linda Fleeman, Dianne Vankan, Jacquie Rand, Grant Morahan

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Genetic variants that are associated with susceptibility to type 2 diabetes (T2D) are important for identification of individuals at risk and can provide insights into the molecular basis of disease. Analysis of T2D in domestic animals provides both the opportunity to improve veterinary management and breeding programs as well as to identify novel T2D risk genes. Australian-bred Burmese (ABB) cats have a 4-fold increased incidence of type 2 diabetes (T2D) compared to Burmese cats bred in the United States. This is likely attributable to a genetic founder effect. We investigated this …


A Platform In The Use Of Medicines To Treat Chronic Hepatitis C (Platinum C): Protocol For A Prospective Treatment Registry Of Real-World Outcomes For Hepatitis C, Jessica Ramsay, Julie Marsh, Alisa Pedrana, Nada Andric, Richard Norman, Wendy Cheng, Steve Webb, Nikolajs Zeps, Matthew Bellgard, Todd Graves, Margaret Hellard, Tom Snelling Jan 2020

A Platform In The Use Of Medicines To Treat Chronic Hepatitis C (Platinum C): Protocol For A Prospective Treatment Registry Of Real-World Outcomes For Hepatitis C, Jessica Ramsay, Julie Marsh, Alisa Pedrana, Nada Andric, Richard Norman, Wendy Cheng, Steve Webb, Nikolajs Zeps, Matthew Bellgard, Todd Graves, Margaret Hellard, Tom Snelling

Research outputs 2014 to 2021

© 2020, The Author(s). Background: Safe, highly curative, short course, direct acting antiviral (DAA) therapies are now available to treat chronic hepatitis C. DAA therapy is freely available to all adults chronically infected with the hepatitis C virus (HCV) in Australia. If left untreated, hepatitis C may lead to progressive hepatic fibrosis, cirrhosis and hepatocellular carcinoma. Australia is committed to eliminating hepatitis as a public health threat by 2030 set by the World Health Organization. However, since the introduction of funded DAA treatment, uptake has been suboptimal. Australia needs improved strategies for testing, treatment uptake and treatment completion to address …


Concordant Peripheral Lipidome Signatures In Two Large Clinical Studies Of Alzheimer’S Disease, Kevin Huynh, Wei Ling Florence Lim, Corey Giles, Kaushala S. Jayawardana, Agus Salim, Natalie A. Mellett, Adam Alexander T. Smith, Gavriel Olshansky, Brian G. Drew, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Matthias Arnold, Kwangsik Nho, Andrew J. Saykin, Rebecca Baillie, Xianlin Han, Rima Kaddurah-Daouk, Ralph N. Martins, Peter J. Meikle Jan 2020

Concordant Peripheral Lipidome Signatures In Two Large Clinical Studies Of Alzheimer’S Disease, Kevin Huynh, Wei Ling Florence Lim, Corey Giles, Kaushala S. Jayawardana, Agus Salim, Natalie A. Mellett, Adam Alexander T. Smith, Gavriel Olshansky, Brian G. Drew, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Matthias Arnold, Kwangsik Nho, Andrew J. Saykin, Rebecca Baillie, Xianlin Han, Rima Kaddurah-Daouk, Ralph N. Martins, Peter J. Meikle

Research outputs 2014 to 2021

© 2020, The Author(s). Changes to lipid metabolism are tightly associated with the onset and pathology of Alzheimer’s disease (AD). Lipids are complex molecules comprising many isomeric and isobaric species, necessitating detailed analysis to enable interpretation of biological significance. Our expanded targeted lipidomics platform (569 species across 32 classes) allows for detailed lipid separation and characterisation. In this study we examined peripheral samples of two cohorts (AIBL, n = 1112 and ADNI, n = 800). We are able to identify concordant peripheral signatures associated with prevalent AD arising from lipid pathways including; ether lipids, sphingolipids (notably GM3 gangliosides) and lipid …


Comparing Web-Based Mindfulness With Loving-Kindness And Compassion Training For Promoting Well-Being In Pregnancy: Protocol For A Three-Arm Pilot Randomized Controlled Trial, Amy Louise Finlay-Jones, Jacqueline Ann Davis, Amanda O'Donovan, Keerthi Kottampally, Rebecca Anne Ashley, Desiree Silva, Jeneva Lee Ohan, Susan L. Prescott, Jenny Downs Jan 2020

Comparing Web-Based Mindfulness With Loving-Kindness And Compassion Training For Promoting Well-Being In Pregnancy: Protocol For A Three-Arm Pilot Randomized Controlled Trial, Amy Louise Finlay-Jones, Jacqueline Ann Davis, Amanda O'Donovan, Keerthi Kottampally, Rebecca Anne Ashley, Desiree Silva, Jeneva Lee Ohan, Susan L. Prescott, Jenny Downs

Research outputs 2014 to 2021

© Amy Louise Finlay-Jones, Jacqueline Ann Davis, Amanda O'Donovan, Keerthi Kottampally, Rebecca Anne Ashley, Desiree Silva, Jeneva Lee Ohan, Susan L Prescott, Jenny Downs. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 14.10.2020. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Research Protocols, is properly cited. The complete bibliographic information, a link to the original publication on http://www.researchprotocols.org, as well as this copyright and license information must be included. Background: Promoting psychological well-being and preventing …


Single Nucleotide Polymorphisms In Lcat May Contribute To Dyslipidaemia In Hiv-Infected Individuals On Haart In A Ghanaian Population, Simon Bannison Bani, Kwabena Owusu Danquah, Christian Obirikorang, William K. B. A. Owiredu, Lawrence Quaye, Edmund Muonir Der, Emmanuel Acheampong, Yussif Adams, Peter Paul M. Dapare, Moses Banyeh, Enoch Odame Anto, Samuel Asamoah Sakyi Jan 2020

Single Nucleotide Polymorphisms In Lcat May Contribute To Dyslipidaemia In Hiv-Infected Individuals On Haart In A Ghanaian Population, Simon Bannison Bani, Kwabena Owusu Danquah, Christian Obirikorang, William K. B. A. Owiredu, Lawrence Quaye, Edmund Muonir Der, Emmanuel Acheampong, Yussif Adams, Peter Paul M. Dapare, Moses Banyeh, Enoch Odame Anto, Samuel Asamoah Sakyi

Research outputs 2014 to 2021

© 2020, The Author(s). Highly active antiretroviral therapy (HAART) is known to cause lipid abnormalities such as dyslipidaemia in HIV-infected individuals. Yet, dyslipidaemia may not independently occur as it may be worsened by single nucleotide polymorphisms (SNPs) in lecithin cholesterol acyltransferase (LCAT) and lipoprotein lipase (LPL). This case–control study was conducted in three-selected hospitals in the Northern part of Ghana. The study constituted a total of 118 HIV-infected participants aged 19–71 years, who had been on HAART for 6–24 months. Dyslipidaemia was defined based on the NCEP-ATP III criteria. HIV-infected individuals on HAART with dyslipidaemia were classified as cases while …


Perceived Influence Of Value Systems On The Uptake Of Voluntary Medical Male Circumcision Among Men In Kweneng East, Botswana, Thandisizwe R. Mavundla, Fungai Mbengo, Khanyenda Bruce Ngomi Jan 2020

Perceived Influence Of Value Systems On The Uptake Of Voluntary Medical Male Circumcision Among Men In Kweneng East, Botswana, Thandisizwe R. Mavundla, Fungai Mbengo, Khanyenda Bruce Ngomi

Research outputs 2014 to 2021

© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Botswana is one of the countries in Eastern and Southern Africa significantly impacted by the Human Immunodeficiency Virus (HIV). To control the spread of HIV, the government in 2009 rolled out the voluntary medical male circumcision (VMMC) programme as an additional HIV prevention strategy with the goal of circumcising 80% of HIV negative men by 2016. However, the country failed to achieve this goal as less than 30% of the targeted men were circumcised by 2016. A study was therefore conducted to explore and describe …


One-Year Outcome And Adherence To Pharmacological Guidelines In First-Episode Schizophrenia: Results From A Consecutive Cohort Study, Petros Drosos, Kolbjørn Brønnick, Inge Joa, Jan Olav Johannessen, Erik Johnsen, Rune Andreas Kroken, Helen Joy Stain, Wenche Ten Velden Hegelstad, Tor Ketil Larsen Jan 2020

One-Year Outcome And Adherence To Pharmacological Guidelines In First-Episode Schizophrenia: Results From A Consecutive Cohort Study, Petros Drosos, Kolbjørn Brønnick, Inge Joa, Jan Olav Johannessen, Erik Johnsen, Rune Andreas Kroken, Helen Joy Stain, Wenche Ten Velden Hegelstad, Tor Ketil Larsen

Research outputs 2014 to 2021

© Wolters Kluwer Health, Inc. All rights reserved. Background Remission in schizophrenia is difficult to achieve. Antipsychotic drugs are critical in the treatment of schizophrenia. International guidelines for the pharmacological treatment of schizophrenia recommend a 3-step algorithm with clozapine being the third-line antipsychotic agent. This study investigated the 1-year outcome and the application of the guidelines for the pharmacological treatment of nonremitted first-episode schizophrenia (FES) patients during the first year of follow-up. Methods A sample of 78 FES patients from the Norwegian TIPS (Early Treatment and Intervention in Psychosis) 2 study was assessed at the end of the first year …


Being The Adult You Needed As A Kid: Why The Aitsl Standards Are Not The Best Fit For Drama Teachers, Christina Gray, Kirsten Lambert Jan 2020

Being The Adult You Needed As A Kid: Why The Aitsl Standards Are Not The Best Fit For Drama Teachers, Christina Gray, Kirsten Lambert

Research outputs 2014 to 2021

© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. The Australian Professional Standards for teachers attempts to regulate the profession and improve teacher quality. Yet the standardisation of teachers’ work has attracted criticism from researchers who assert that a “one size fits all” model for judging teacher quality fails to recognise the affective, enactive and relational aspects of teaching. Given the interactive and interpersonal nature of teaching drama, this concern has salience. Our research into the experiences of early-career drama teachers reveals the positive influence these teachers have on their students and in their …