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Obturator Nerve Block With Aqueous Phenol Reduces Hip Adductor Spasticity – A Single Centre Experience, Sarah Razaq, Fahim Anwar, Muhammad Aleem Arshad

Pakistan Journal of Neurological Sciences (PJNS)

ABSTRACT

Aim: Spasticity is a cardinal symptom of upper motor neuron disorders. It affects different individuals differently.

Spasticity in the hip adductor muscles can be very painful and may result in postural abnormalities and hip deformities

that interfere with walking, transferring and perineal hygiene. The study aimed to assess the effectiveness of phenol

obturator nerve block on hip adductor spasticity caused by the upper motor neuron lesions.

Materials and methods: This is a single-centre retrospective study of all patients with known spasticity in the hip

adductors who were assessed suitable for phenol nerve block of the obturator nerve. All patients …

Assessment Of Dementia Caregiver Burden In Karachi, Pakistan Using 10/66 Protocol, Qurat Ul Ain Khan

Pakistan Journal of Neurological Sciences (PJNS)

ABSTRACT INTRODUCTION: Care arrangements and caregiver burden of people with dementia (PWD) are different in low and middle income countries (LMICs) than in developed countries. This is the first study in Pakistan assessing caregiver burden using the 10/66 protocol. METHOD: PWD were recruited from outpatient clinics and from the community in Karachi and were diagnosed according to DSM-IV TR. Three scales were used: 1. Zarit Burden Interview (ZBI) to assess caregiver burden. 2. Caregiver Activity Survey (CAS) to assess activities that the caregiver engaged in the last 24 hours to care for PWD and 3. General Health Questionnaire- 12 (GHQ …

A Case Of Heroin Induced Toxic Leukoencephalopathy, Sidra Sattar, Saba Zaidi

Pakistan Journal of Neurological Sciences (PJNS)

ABSTRACT: Heroin-induced leukoencephalopathy comes under the category of Toxic leukoencephalopathies. We report the case of middle-aged gentleman with the history of polysubstance abuse who presented with recurrent falls, difficulty in walking and drowsiness. Diffuse white matter changes were appreciated on MRI Brain with sparing of cerebellum. In context of his history of inhalational heroin abuse with extensive symmetrical white matter changes in cerebrum, a diagnosis of heroin induced toxic leukoencephalopathy was made.

Hemichorea Associated With Type 2 Diabetes: A Rare Neurological Complication, Waleed Shahzad, Tehmina Inayat, Fibhaa Syed, Mohammad Ali Arif, Muhammad Hassan, Haris Majid Rajput, Mazhar Badshah

Pakistan Journal of Neurological Sciences (PJNS)

Diabetic hemichorea/hemiballism is a spectrum of hyper kinetic, involuntary, irregular, purposeless, non-rhythmic, rapid and unsustained movements flowing from one part of the body to another. It involves contra lateral basal-ganglia and often striatum of the brain. Here we are reporting an un-usual case of choreiform movement disorder which was sudden in onset. It was accompanied with abnormally high values of blood glucose. Our patient had a complete remission of symptoms after an adequate control of blood glucose was achieved. This case illustrates the importance and rarity of hyperglycemia as a rare cause of hemichorea. It recovers rapidly and has a …

Longitudinally Extensive Transverse Myelitis And Neuromyelitis Optica Spectrum Disorder: A Tertiary Care Centre Experience, Safia Bano, Muhammad Athar Javed, Ahsan Numan

Pakistan Journal of Neurological Sciences (PJNS)

ABSTRACT OBJECTIVE: To determine the frequency of longitudinally extensive transverse myelitis and Causes of longitudinally extensive transverse myelitis METHODOLOGY: A Cross-Sectional, retrospective study was conducted at Neurology Department, Mayo Hospital, Lahore from 1st January 2015 to 31st December 2015. Patients were included from inpatient with history of weakness of lower limbs/all four limbs with or without visual disturbances. History and clinical examination was consistent with transverse myelitis. Neuroimaging (MRI brain, (orbit in case of optic neuritis) and spinal cord) was done followed by LP/CSF, Vasculitis screening.

Digital Diet: Addressing The Effects Of Social Media & Internet Addiction On Stress And Anxiety Levels In Students, Brianna Janey

Senior Honors Theses

The contents of this thesis will address the effects of social media and internet addiction on stress and anxiety levels within students. The research process began by comprehensively defining the problem as being how online usage affects the levels of stress and anxiety within students. After establishing the problem, a review of existing literature presenting possible solutions to this problem was conducted. Each artifact was assessed for overall effectiveness in relation to the target demographic. Finally, a cohesive digital social good campaign that seeks to encourage students to create mindful online habits is presented as a creative solution that successfully …

The Bridge Newsletter Winter 2020, Missouri University Of Science And Technology

The Bridge Newsletter

-Kummers give largest single gift in the history of Missouri higher education
-$1M gift from the Sunderland Foundation completes ACML lab
-Miner alumni step up
-Academy of Civil Engineers inducts 11 new members

2020 December 1, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes, December 1, 2020

SUNY Cortland Student Testimonials on Fall 2020

A Litigator’S Guide To The Galaxy: A Look At The Pragmatic Questions For Adjudicating Future Outer Space Disputes, Michael J. Listner, Joshua T. Smith

Vanderbilt Journal of Entertainment & Technology Law

Since the beginnings of the space age, outer space activities have been the realm of government with ancillary involvement by non-governmental actors. The international legal framework for outer space contemplated the involvement of non-governmental actors, but in creating dispute resolution mechanisms the role of non-governmental entities was not considered ripe. The surge of direct non-governmental involvement in outer space activities in recent years again raises the issue of dispute resolution and exemplifies the lack of dispute resolution mechanisms designed to address differences between sovereign states. As the pace of non-governmental activity increases, so does the likelihood of disputes arising between …

When Helping Hurts: Covid-19 Critical Incident Involvement And Resource Depletion In Health Care Workers, Miguel Caldas, Kathryn Ostermeier, Danielle Cooper

Applied Psychology Department Faculty Journal Articles

A focus on helping others is generally lauded, particularly in medicine, but in the context of a pandemic when health care professionals are facing increased risk, loss, and trauma, this focus can potentially be detrimental. In this study, we sought to (a) examine if health care workers intensely involved in the coronavirus 2019 (COVID-19) pandemic are experiencing negative psychological and emotional outcomes, and (b) investigate if helping related factors (prosocial motivation and perceived prosocial impact) exacerbate and mitigate relationships to negative outcomes in a crisis situation. Using data collected from doctors and nurses before and during the COVID-19 pandemic, we …

Transfer Learning With Chest X-Rays For Er Patient Classification, Jonathan Stubblefield, Mitchell Hervert, Jason L. Causey, Jake A. Qualls, Wei Dong, Lingrui Cai, Jennifer Fowler, Emily Bellis, Karl Walker, Jason H. Moore, Sara Nehring, Xiuzhen Huang

Arkansas Biosciences Institute

One of the challenges with urgent evaluation of patients with acute respiratory distress syndrome (ARDS) in the emergency room (ER) is distinguishing between cardiac vs infectious etiologies for their pulmonary findings. We conducted a retrospective study with the collected data of 171 ER patients. ER patient classification for cardiac and infection causes was evaluated with clinical data and chest X-ray image data. We show that a deep-learning model trained with an external image data set can be used to extract image features and improve the classification accuracy of a data set that does not contain enough image data to train …

Point Blue Conservation Science, Mark Dettling, Diana Humple

North American Bird Bander

No abstract provided.

Fundamentals Of Teaching Vocal Music Performance, Malcolm Shaquan Richardson

Masters Theses

This study outlines the significance and sole purpose of developing fundamental techniques of student vocal music performances, using professional constructive evaluation that will improve their overall performance experience. One of the most practical ways to support vocalists is to provide a constructive evaluation of their performances. The implementation of constructive evaluation is to reflect upon what is being done well, discover areas of improvement or refinement, plan and facilitate important lessons, and apply the lessons to future performances. As a music teacher who is actively overseeing the development of students as performing or creating musicians, including constructive evaluation is a …

Resilience: Structure And Function, Derrick Manns, Bob D. Lee, David L. Groves

Visions in Leisure and Business

The primary purpose after the establishment of the conceptual framework was an analysis to identify potential causal influences related to structure and function. The many impacts of the virus are too numerous to catalog. Those elements that were identified are just beginning to develop an understanding of how a crisis such as a pandemic influences all segments of society. One element that had greatest impact was the severity of the COVID 19 virus upon the individual and their immediate family and/or social group. The real outcome was a time of reflection of those individuals that were isolated because of the …

Envisioning An Age Friendly Stoneham, Caitlin Coyle, Mary Krebs

Center for Social and Demographic Research on Aging Publications

Tucked between two major highways, about nine miles from Boston, the Town of Stoneham is currently home to more than 22, 000 residents, 27% of which are age 60 and older. According to projections created by the Donahue Institute at the University of Massachusetts, a trend toward an older population in Stoneham is expected in future decades. Donahue Institute vintage projections suggest that by 2035, more than one out of each three Stoneham’s residents will be age 60 or older—28% of the town’s population will be between the ages of 60 and 79, with an additional 10% age 80 and …

Aging Strong For All: Examining Aging Equity In The City Of Boston, Jan Mutchler, Caitlin Coyle, Nidya Velasco Roldán, Paul Watanabe, Cedric Woods, Lorna Rivera, Quito Swan, Elena Stone, Laurie Nsiah-Jefferson

Center for Social and Demographic Research on Aging Publications

The experience of being and becoming older differs substantially based on one’s race, ethnicity, and gender. In the City of Boston, it has never been more critical to strategically pursue greater equity in the aging experience of residents. According to data from the US Census Bureau, the number of Boston residents aged 60 or older increased by more than a third just since 2010 and persons of color now make up half of Boston’s older adults. As well, stakeholders share a growing recognition of the powerful ways in which inequity, racism and discrimination shape health outcomes and the aging experience, …

Bystanders’ Perspectives On The Provision Of Informal, Hospital-Based Care To Bedridden Patients With Cancer In Sri Lanka, B. Sunil S. De Silva

Nursing ETDs

Due to the nursing shortage in Sri Lanka, patients need informal caregivers, known as bystanders, to help provide patient care. This study described bystanders’ perspectives on informal, hospital-based care to bedridden patients with cancer in Sri Lanka. In this qualitative descriptive study, 17 bystanders at Apeksa/Cancer Hospital, Sri Lanka, were recruited using snowballing sampling. Data were collected through telephone interviews and analyzed using content and thematic analyses. Findings showed that paid and unpaid bystanders cover all caregiving tasks with minimum interaction with nurses. Unpaid bystanders described the need for same-sex bystanders and additional help with patients’ mobilization and specialized care. …

Through The Funnel: A Critical Policy Analysis Of Educational Policy Relating To The School-To-Prison Pipeline., Jesse V. Hall

Special Education ETDs

The purpose of the present study involved analyzing the policies of the Trump administration to determine the ways it impacted the school-to-prison pipeline. The focus of the study included the Departments of Education and Justice. The findings revealed educational policies and deregulatory practices that maintained and intensified the school-to-prison pipeline.

Quantification Of Nitric Oxide Via Single-Walled Carbon Nanotubes, Jakob Meier

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Nitric oxide (NO), a free radical present in biological systems, can have many beneficial and detrimental effects on the body. Due to NO’s short half-life, its detection and quantification is difficult. This inability to quantify NO has hindered researchers that are trying to understand NO’s impact in healthy and diseased conditions. Single-walled carbon nanotubes (SWNT), can become selective to various analytes when wrapped in specific single-stranded DNA strands. The presence of the analyte of interest can change the wavelength and/or intensity of the SWNT’s fluorescence, allowing the SWNT to be used as a sensor. One type of SWNT sensor, 6,5 …

The Role Of Liver Sinusoidal Endothelial Cells In Liver Malady Homeostasis, Fatima Cabral

Department of Biochemistry: Dissertations, Theses, and Student Research

Current literature described techniques for the purification of liver cell types through text alone. The techniques described for the isolation of liver sinusoidal endothelial cells as well as hepatocytes described here are modified from a published article in the Journal of Visualized experiments. The video protocol allows for the user to successfully isolate cells as the most difficult parts of the procedure are demonstrated visually. The detection of liver maladies such as the non-alcoholic fatty liver disease, the stage if this disease and differentiation between non-alcoholic and alcoholic fatty liver disease is demonstrated in the development of a unique panel …

Women In Beekeeping: Impacts Of A Beekeeper Educational Program, Bridget Gross

Department of Entomology: Dissertations, Theses, and Student Research

The decline in honey bee populations over the past two decades in the United States is alarming. The management provided by beekeepers to their honey bee colonies influences the survival of the colony. However, there is a lack of information on the experiences of beekeepers, specifically women beekeepers. The Center for Rural Affairs (CFRA) in Nebraska hosted the “Honey Bees on the Farm: Connecting Women Beekeepers and Women Farmers for Environmental and Economic Benefit” program that provided informal, educational events to women beekeepers and landowners. Using a convergent mixed methods design, the first research question examines the impacts of the …

Heat And Mass Transfer In Micropolar Model For Blood Flow Through A Stenotic Tapered Artery, Moses S. Dada, Funmilola Alamu-Awoniran

Applications and Applied Mathematics: An International Journal (AAM)

Heat and mass transfer in blood flow through a tapered artery with mild stenosis is examined. The blood is considered to be an incompressible, micropolar fluid flowing through a vessel with nonsymmetric axial and symmetric radial axes. The geometry of the model takes into account the shape parameter, tapered angle and height of the stenosis.The variation in the shape parameter is used to describe the changes in the axial shape of the stenosis in the artery. The governing equations for the model, comprising the continuity, momentum, energy, and mass transfer equations are transformed and simplified under the assumption of mild …

Using Expanded Natural Killer Cells As Therapy For Invasive Aspergillosis, Win Mar Soe, Joan Hui Juan Lim, David L. Williams, Jessamine Geraldine Goh, Zhaohong Tan, Qi Hui Sam, Sanjay H. Chotirmall, Nur A’Tikah Binte Mohamed Ali, Soo Chin Lee, Ju Ee Seet, Sharada Ravikumar, Louis Yi Ann Chai

ETSU Faculty Works

Invasive aspergillosis (IA) is a major opportunistic fungal infection in patients with haematological malignancies. Morbidity and mortality rates are high despite anti-fungal treatment, as the compromised status of immune system prevents the host from responding optimally to conventional therapy. This raises the consideration for immunotherapy as an adjunctive treatment. In this study, we evaluated the utility of expanded human NK cells as treatment against Aspergillus fumigatus infection in vitro and in vivo. The NK cells were expanded and activated by K562 cells genetically modified to express 4-1BB ligand and membrane-bound interleukin-15 (K562-41BBL-mbIL-15) as feeders. The efficacy of these cells was …

Large Subcapsular Hematoma Of The Liver Due To Faja Corset: A Rare Case Report, Sheharyar Minhas, Ahmed Minhas, Maira Malik, Phaniram Sumanam

ETSU Faculty Works

Background: Subcapsular hematoma of the liver is a potentially life-threatening but extremely rare condition. It is often caused by a blunt trauma or other predisposing conditions such as a liver tumor, intra-tumor hemorrhage, surgery, preeclampsia, liver biopsy, and hemodialysis. Predisposing causes of liver hematoma include its large size and proximity to fixed structures. To date, there have been no reported cases of subcapsular liver hematoma caused by tight clothing such as corsets. Our case report is about an extremely rare case of subcapsular hematoma of the liver caused by wearing a tight faja corset in a young healthy female. Case …

Telomeric Injury By Kml001 In Human T Cells Induces Mitochondrial Dysfunction Through P53-Pgc-1Α Pathway, Madison Schank, Juan Zhao, Ling Wang, Zhengke Li, Dechao Cao, Lam Nhat Nguyen, Xindi Dang, Sushant Khanal, Lam Ngoc Thao Nguyen, Bal Krishna Chand Thakuri, Stella C. Ogbu, Zeyuan Lu, Jinyu Zhang, Xiao Y. Wu, Zheng D. Morrison, Mohamed El Gazzar, Shunbin Ning, Jonathan P. Moorman, Zhi Q. Yao

ETSU Faculty Works

Telomere erosion and mitochondrial dysfunction are prominent features of aging cells with progressive declines of cellular functions. Whether telomere injury induces mitochondrial dysfunction in human T lymphocytes, the major component of adaptive host immunity against infection and malignancy, remains unclear. We have recently shown that disruption of telomere integrity by KML001, a telomere-targeting drug, induces T cell senescence and apoptosis via the telomeric DNA damage response (DDR). In this study, we used KML001 to further investigate the role and mechanism of telomere injury in mitochondrial dysregulation in aging T cells. We demonstrate that targeting telomeres by KML001 induces mitochondrial dysfunction, …

Lncrna Hotairm1 Promotes Mdsc Expansion And Suppressive Functions Through The Hoxa1-Mir124 Axis During Hcv Infection, Bal Krishna Chand Thakuri, Jinyu Zhang, Juan Zhao, Lam N. Nguyen

ETSU Faculty Works

HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) is a long non-coding RNA (lncRNA) that plays a pivotal role in regulating myeloid cell development via targeting HOXA1 gene expression. We and others have previously shown that myeloid-derived suppressor cells (MDSCs), a heterogeneous population of immature myeloid cells, expand during chronic viral (HCV, HIV) infections. However, the role of HOTAIRM1 in the development and suppression of MDSCs during viral infection remains unknown. In this study, we demonstrate that the expressions of HOTAIRM1 and its target HOXA1 are substantially upregulated to promote the expressions of immunosuppressive molecules, including arginase 1, inducible nitric oxide …

Interventions To Support Staff Caring For Pediatric Behavioral Health Patients In The Emergency Department, Jennifer L. Mattei, Denise Bach, Rebecca Neichter

General Submissions: Presentations (Oral and Poster)

Emergency departments (ED) across the country continue to see increasing volumes of behavioral health (BH) patients. With this increased volume, an increased number of aggressive patients has also been noted. The staff in our pediatric ED frequently expressed their uneasiness when caring for BH patients, and voiced concern over the number of resources being allocated to BH patients. The purpose of this evidence based practice (EBP) project was to discover what additional resources would be perceived by staff to be the most beneficial to increase their safety, comfort level and job satisfaction when caring for BH patients.

Pediatric Severe Sepsis Checklist Improves Timeliness Of Treatment, Sarah Maciolek, Kelly Perez, Megan Hughes, Emily C. Dawson

General Submissions: Presentations (Oral and Poster)

The 2017 American College of Critical Care Medicine recommends a first-hour resuscitation and stabilization bundle for the treatment of pediatric severe sepsis or septic shock. Priorities of care include rapid establishment of vascular access, initiation of fluid resuscitation within 30 minutes, and initiation of empiric antimicrobial therapy within 60 minutes of severe sepsis recognition. The utilization of a protocolized treatment in the Pediatric Emergency Department (ED) is associated with improved timeliness of care and reduced morbidity related to organ dysfunction. The purpose of this evidence-based practice (EBP) project is to improve timeliness of antibiotic administration and intravenous fluid bolus administration …

How To Be A First Responder For Colleagues After Adverse Events: Instituting A Peer Support Program In The Emergency Department, Kerry A. Gold, Melissa Connor, Ashley Trueblood

General Submissions: Presentations (Oral and Poster)

Healthcare workers exposed to adverse events can suffer emotional and physical consequences, often referred to as "second-victim" or "identified individual" After an adverse event occurs, there may be immediate, midterm, and delayed harm to the caregivers involved, including: increased depression, anxiety about future errors, loss of confidence, sleeping difficulties, reduced job satisfaction, and harm to their reputation. In our health system, the Emergency Department (ED) is subject to the highest number of staff assaults, workplace violence and critical events. With this knowledge, an interdisciplinary team was created to address the issues. The objective was to implement a peer support team …

Identification Of Human Trafficking Victims In The Emergency Department, Susan G. Blume

General Submissions: Presentations (Oral and Poster)

Healthcare professionals have not been successful in identifying human trafficking victims. Lack of recognition is related to inadequate training and screening tools. No patients had been identified as potential human trafficking victims in our Emergency Department prior to the initiation of this project. This was a staff development evidenced based practice project. We wanted to educate the staff on how to identify human trafficking victims in the clinical setting. Once patients were identified the staff had to be educated on how to respond appropriately to this patient population.