Digital Commons Network^™

Mobile Health In Cardiology – A Review, Keshav Goyal

Manipal Journal of Science and Technology

Cardiovascular disease is the leading global cause of mortality and morbidity. With the widespread and growing usage of smartphones and mobile apps, the use of mobile health (mHealth) in the transmission of physiological parameters and patient-referred symptoms to healthcare professionals and researchers, as well as in the application of notifications and treatment plans from professionals to patients, has the potential to revolutionize the conduct of clinical trials with improved designs, data collection, and reduced costs. In addition, the wide- ranging adoption of ever more advanced mobile applications (apps) and devices offers mobile health the ability to expand on telecardiology, which …

A New Governance Approach To Regulating Human Genome Editing, John M. Conley, Arlene M. Davis, Gail E. Henderson, Eric T. Juengst, Karen M. Meagher, Rebecca L. Walker, Margaret Waltz, Jean Cadigan

North Carolina Journal of Law & Technology

No abstract provided.

Judges Breaking The Law: An Empirical Study Of Financially Interested Judges Deciding Cases, Benjamin B. Johnson, John Newby Parton

North Carolina Law Review

No abstract provided.

Effects Of Daily 24-Gram Doses Of Rice Or Whey Protein On Resistance Training Adaptations In Trained Males, Jessica M. Moon, Kayla M. Ratliff, Julia C. Blumkaitis, Patrick S. Harty, Hannah A. Zabriskie, Richard A. Stecker, Brad S. Currier, Andrew R. Jagim, Ralf Jäger, Martin Purpura, Chad M. Kerksick

Faculty Scholarship

Large (48-g), isonitrogenous doses of rice and whey protein have previously been shown to stimulate similar adaptations to resistance training, but the impact of consuming smaller doses has yet to be compared. We evaluated the ability of 24-g doses of rice or whey protein concentrate to augment adaptations following 8 weeks of resistance training.

A Theacrine-Based Supplement Increases Cellular Nad+ Levels And Affects Biomarkers Related To Sirtuin Activity In C2c12 Muscle Cells In Vitro, Petey W. Mumford, Shelby C. Osburn, Carlton D. Fox, Joshua S. Godwin, Michael D. Roberts

Faculty Scholarship

There is evidence in rodents to suggest that theacrine-based supplements modulate tissue sirtuin activity as well as other biological processes associated with aging. Herein, we examined if a theacrine-based supplement (termed NAD3) altered sirtuin activity in vitro while also affecting markers of mitochondrial biogenesis. The murine C2C12 myoblast cell line was used for experimentation. Following 7 days of differentiation, myotubes were treated with 0.45 mg/mL of NAD3 (containing ~2 mM theacrine) for 3 and 24 h (n = 6 treatment wells per time point). Relative to control (CTL)-treated cells, NAD3 treatments increased (p < 0.05) Sirt1 mRNA levels at 3 h, as well as global sirtuin activity at 3 and 24 h. Follow-up experiments comparing 24 h NAD3 or CTL treatments indicated that NAD3 increased nicotinamide phosphoribosyltransferase (NAMPT) and SIRT1 protein levels (p < 0.05). Cellular nicotinamide adenine dinucleotide (NAD+) levels were also elevated nearly two-fold after 24 h of NAD3 versus CTL treatments (p < 0.001). Markers of mitochondrial biogenesis were minimally affected. Although these data are limited to select biomarkers in vitro, these preliminary findings suggest that a theacrine-based supplement can modulate select biomarkers related to NAD+ biogenesis and sirtuin activity. However, these changes did not drive increases in mitochondrial biogenesis. While promising, these data are limited to a rodent cell line and human muscle biopsy studies are needed to validate and elucidate the significance of these findings.

Fenugreek Counters The Effects Of High Fat Diet On Gut Microbiota In Mice: Links To Metabolic Benefit, Annadora J. Bruce-Keller, Allison J. Richard, Sun Ok Fernandez-Kim, David M. Ribnicky, J. Michael Salbaum, Susan Newman, Richard Carmouche, Jacqueline M. Stephens

Faculty Publications

© 2020, The Author(s). Fenugreek (Trigonella foenum-graecum) is an annual herbaceous plant and a staple of traditional health remedies for metabolic conditions including high cholesterol and diabetes. While the mechanisms of the beneficial actions of fenugreek remain unknown, a role for intestinal microbiota in metabolic homeostasis is likely. To determine if fenugreek utilizes intestinal bacteria to offset the adverse effects of high fat diets, C57BL/6J mice were fed control/low fat (CD) or high fat (HFD) diets each supplemented with or without 2% (w/w) fenugreek for 16 weeks. The effects of fenugreek and HFD on gut microbiota were comprehensively mapped and …

Organizational And Partisan Brokerage Of Social Benefits: Social Policy Linkages In Mexico, Candelaria Garay, Brian Palmer-Rubin, Mathias Poertner

Political Science Faculty Research and Publications

The expansion of large-scale non-discretionary social policy has been one of the most important policy innovations in Latin America in recent decades. While these benefits have reduced the political manipulation of low-income citizens, discretionary social programs—whose distribution follows opaque criteria and are often allocated according to political considerations—continue to exist. Employing an original survey in Mexico, we explore how citizens, both beneficiaries and non-beneficiaries, experience and perceive access to discretionary social programs. While the literature on clientelism emphasizes the distribution of discretionary benefits by party agents in exchange for electoral support, a number of recent studies have found that access …

Engaging Nursing Students And Older Adults Through Service-Learning, Christine S. Gipson, Julie A. Delello, Rochell Mcwhorter

Human Resource Development Faculty Publications and Presentations

Purpose

The purpose of this study is to examine nursing students’ (n = 18) perceptions of interrelating with older adults to understand how such interactions might improve students’ levels of cultural competence and enhance their future nursing practice. Additionally, the study sought to contribute to a higher level of technological competency in older adults.

Design/methodology/approach

A basic qualitative study design (Merriam and Tisdell, 2016) was used to direct the data collection and analysis to achieve the aims of this study.

Findings

Four themes emerged from the data collected based on cultural knowledge, cultural skills, cultural desire and engaging in …

Impact Of Tax Revenue On Economic Growth In Nigeria (1981-2017), Abubakar Biliksu Aliyu, A. A. Mustapha

Bullion

The main objective of this research is to assess empirically the impact of tax revenue on economic growth in Nigeria, spanning from 1981 to 2017. It employs, time series data obtained from the CBN statistical bulletins, FIRS annual publications and National Bureau of Statistics (NBS) portal. To achieve the objectives of the study, OLS and ARDL techniques were employed to estimate the relationships and the dynamics and longrun effects of independent variables on dependent variable. ARDL bound test revealed that the variables are cointegrated while ARDL long-run estimation indicated that petroleum profit, value added tax and government domestic debt are …

A Model Of Sequential Crisis Management, Fei Li, Jidong Zhou

Cowles Foundation Discussion Papers

We propose a model of how multiple societies respond to a common crisis. A government faces a "damned-either-way" policymaking dilemma: aggressive intervention contains the crisis, but the resulting good outcome makes people skeptical about the costly response; light intervention worsens the crisis and causes the government to be faulted for not doing enough. When multiple societies encounter the crisis sequentially, due to this policymaking dilemma, late societies may underperform despite having more information, while early societies can benefit from a dynamic counterfactual effect.

The Scoop, Vol. 7 Issue 9, December 2020, Health Sciences Library

Volume 7

Latest news and updates from the Health Sciences Library in our monthly newsletter for December 2020.

Mb4t (Mathematics By And For Teachers): Bringing Data Science Into The Elementary Classroom, Jennifer Holm

Education Faculty Publications

No abstract provided.

Full Issue

International Journal of Interpreter Education

No abstract provided.

Use Of A Signing Bioscience Dictionary In Increasing Student Interpreters’ American Sign Language Life Science Vocabulary, Judy Vesel, Diane Clark, Tara Robillard

International Journal of Interpreter Education

Interpreters who are skilled in academic ASL content, such as the vocabulary needed to interpret postsecondary science courses, are rare. This is not surprising, because interpreting training programs focus on developing the skills to fluently interpret from sign to voice as well as voice to sign, not on the specialized vocabulary for more specialized content. This study examined the impact of training interpreting students on the use of a Signing Bioscience Dictionary (SBD). Research involved incorporating terms found in undergraduate biology courses into the SBD, conducting an evaluation, and soliciting recommendations for improvement of the SBD. Key findings showed that …

Interview With Samoan-English Specialist Mental Health Interpreter Hoy Neng Wong Soon, Jo Anna Burn, Hoy Neng Wong Soon

International Journal of Interpreter Education

This interview was conducted with Hoy Neng Wong Soon, a specialist mental health Samoan-language interpreter from Aotearoa New Zealand³ . Hoy Neng combines her work as a research project manager with the Pacific Islands Families Study with interpreting and translating and also works as a health interpreter and translator educator. Her experiences offer interpreters and educators an insight into mental health settings and into the very demanding area of forensic psychiatry. She is based in Auckland, Aotearoa New Zealand.

Covid-19 Newsletter (Vol. 48), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Prevention Of Pediatric Mortality Associated With Malaria: An Exhaustive Literature Review, Taylor Mosley

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Malaria, a disease that is preventable yet frequently fatal, disproportionately affects pediatric African populations at a rate that results in a child under the age of 5 dying every two minutes. Since 1955, the World Health Organization has contributed to a significant reduction in the morbidity and mortality of malaria; however, progress has stalled in recent years. In some countries, particularly those in sub-Saharan Africa, cases have increased since 2015. This literature review seeks to identify factors associated with this incline, as well as what interventions can have the greatest impact to prevent pediatric mortality in areas with the largest …

Improving Clinicians’ Access To Patient Education And Va Resource Information, Ella Bermudez

Doctor of Nursing Practice (DNP) Projects

Abstract

Problem: In a western US Veterans Administration (VA) hospital system, patient education materials are provider-specific, not standardized, and not located in a central, readily available location.

Context: How does a patient education tool affect the clinicians' delivery of health education in increasing health literacy compared to written information alone in the US veteran population? An integrated literature review was performed using Cochrane, Joanna Briggs Institute (JBI), Scopus, CINAHL, and PubMed databases to address the PICOT question above and determine the impact of patient education tools on health literacy and patient engagement. The literature recommended improving patient education for better …

Calorie Restriction For Enhanced Longevity: The Role Of Novel Dietary Strategies In The Present Obesogenic Environment, James L. Dorling, Corby K. Martin, Leanne M. Redman

Clinical Research Faculty Publications

Calorie restriction (CR) is a potent modulator of longevity in multiple species. A growing body of evidence shows that sustained periods of CR without malnutrition improves risk factors involved in the pathophysiology of type 2 diabetes, cardiovascular diseases, cancer, and neurological disorders in humans. Innovative dietary strategies such as intermittent fasting and protein restriction have recently emerged as alternative approaches that improve markers of aging. Some of these newer strategies might provide benefits for healthy aging with little to no CR and therefore, compared to traditional CR, may be easier to follow. Further to providing an update of CR studies …

Challenges And Opportunities With Causal Discovery Algorithms: Application To Alzheimer’S Pathophysiology, Xinpeng Shen, Sisi Ma, Prashanthi Vemuri, Gyorgy Simon, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, Andrew J. Saykin, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Maria Carrillo, Lew Kuller, Marc Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, David Holtzman, M. Marcel Mesulam, William Potter, Peter Snyder, Adam Schwartz, Tom Montine, Ronald G. Thomas, Michael Donohue, Sarah Walter

Clinical Research Faculty Publications

Causal Structure Discovery (CSD) is the problem of identifying causal relationships from large quantities of data through computational methods. With the limited ability of traditional association-based computational methods to discover causal relationships, CSD methodologies are gaining popularity. The goal of the study was to systematically examine whether (i) CSD methods can discover the known causal relationships from observational clinical data and (ii) to offer guidance to accurately discover known causal relationships. We used Alzheimer’s disease (AD), a complex progressive disease, as a model because the well-established evidence provides a “gold-standard” causal graph for evaluation. We evaluated two CSD methods, Fast …

Muhlenberg Magic, Lehigh Valley Health Network

LVHN documents

No abstract provided.

Imposter Syndrome In Academia, Emily Faulconer

Publications

Defining Imposter Syndrome

• Despite evidence, fears being exposed as not having the expertise expected in your role.
• Despite evidence, feels like a fraud.
• Attributes success to luck, masking skills, or the work of other people.
• Internalizes failure and over-focus on mistakes.
• Over-estimates abilities of others, underestimates amount of work those individuals put in.

Imagining A Lean And Agile Digital Health Ecosystem - A Measure Of Pandemic Responsiveness, Zainab Samad, Sana Mahmood, Sameen Siddiqi, Zulfiqar Ahmed Bhutta

Section of Cardiology

No abstract provided.

Comparison Of Conventional And Advanced Radiotherapy Techniques For Left-Sided Breast Cancer After Breast Conserving Surgery, Yibo Xie, Daniel Bourgeois, Beibei Guo, Rui Zhang

Faculty Publications

Whole breast radiotherapy (WBRT) after breast conserving surgery is the standard treatment to prevent recurrence and metastasis of early stage breast cancer. This study aims to compare seven WBRT techniques including conventional tangential, field-in-field (FIF), hybrid intensity-modulated radiotherapy (IMRT), IMRT, standard volumetric modulated arc therapy (STD-VMAT), noncoplanar VMAT (NC-VMAT), and multiple arc VMAT (MA-VMAT). Fifteen patients who were previously diagnosed with left-sided early stage breast cancer and treated in our clinic were selected for this study. WBRT plans were created for these patients and were evaluated based on target coverage and normal tissue toxicities. All techniques produced clinically acceptable WBRT …

Women Leaders And Policy Compliance During A Public Health Crisis, Nichole M. Bauer, Jeong Hyun Kim, Yesola Kweon

Faculty Publications

How does the gender of a political leader affect policy compliance of the public during a public health crisis? State and national leaders have taken a variety of policy measures to combat the COVID-19 pandemic, with varying levels of success. While many female leaders have been credited with containing the spread of COVID-19, often through implementing strict policy measures, there is little understanding of how individuals respond to public health policy recommendations made by female and male leaders. This article investigates whether citizens are more willing to comply with strict policy recommendations about a public health issue when those recommendations …

Octenidine/Carbenicillin Gumbos As Potential Treatment For Oropharyngeal Gonorrhoea, Kelsey M. Lopez, Jeffrey A. Hobden, Isiah M. Warner

Faculty Publications

© The Author(s) 2020. Background: Reducing Neisseria gonorrhoeae colonies in the oropharynx is a viable solution to minimize the transmission of this bacterium amongst individuals. Objectives: A strategy involving the electrostatic interaction between a common antiseptic and a discontinued antibiotic (i.e. octenidine and carbenicillin) was evaluated as a potential treatment for gonorrhoea. Octenidine/carbenicillin is a novel group of uniform materials based on organic salts (GUMBOS) with inherent in vitro antibacterial activity that comes from its parent antiseptic and antibacterial ions, octenidine and carbenicillin, respectively. Methods: Antibacterial activities for octenidine dihydrochloride, disodium carbenicillin, octenidine/carbenicillin and stoichiometrically equivalent 1:1 octenidine dihydrochloride to …

Qcm Sensor Arrays, Electroanalytical Techniques And Nir Spectroscopy Coupled To Multivariate Analysis For Quality Assessment Of Food Products, Raw Materials, Ingredients And Foodborne Pathogen Detection: Challenges And Breakthroughs†, David K. Bwambok, Noureen Siraj, Samantha Macchi, Nathaniel E. Larm, Gary A. Baker, Rocío L. Pérez, Caitlan E. Ayala, Charuksha Walgama, David Pollard, Jason D. Rodriguez, Souvik Banerjee, Brianda Elzey, Isiah M. Warner, Sayo O. Fakayode

Faculty Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Quality checks, assessments, and the assurance of food products, raw materials, and food ingredients is critically important to ensure the safeguard of foods of high quality for safety and public health. Nevertheless, quality checks, assessments, and the assurance of food products along distribution and supply chains is impacted by various challenges. For instance, the development of portable, sensitive, low-cost, and robust instrumentation that is capable of real-time, accurate, and sensitive analysis, quality checks, assessments, and the assurance of food products in the field and/or in the production line in a food …

Mobilization Of Iron Stored In Bacterioferritin Is Required For Metabolic Homeostasis In Pseudomonas Aeruginosa, Achala N.D. Punchi Hewage, Leo Fontenot, Jessie Guidry, Thomas Weldeghiorghis, Anil K. Mehta, Fabrizio Donnarumma, Mario Rivera

Faculty Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Iron homeostasis offers a significant bacterial vulnerability because pathogens obtain essential iron from their mammalian hosts, but host-defenses maintain vanishingly low levels of free iron. Although pathogens have evolved mechanisms to procure host-iron, these depend on well-regulated iron homeostasis. To disrupt iron homeostasis, our work has targeted iron mobilization from the iron storage protein bacterioferritin (BfrB) by blocking a required interaction with its cognate ferredoxin partner (Bfd). The blockade of the BfrB–Bfd complex by deletion of the bfd gene (∆bfd) causes iron to irreversibly accumulate in BfrB. In this study we …

Development Of A Degree-Day Model To Predict Egg Hatch Of Aedes Albopictus, Kristen B. Healy, Emily Dugas, Dina M. Fonseca

Faculty Publications

Aedes albopictus, the Asian tiger mosquito, is an important nuisance mosquito species and known vector of arboviruses such as dengue, chikungunya, and Zika. Despite their cosmopolitan distribution around the world, there is a paucity of accurate predictive models based on rates of development at different temperatures (degree-day models). These types of models can benefit mosquito control districts by predicting when to target early-season larval development, when populations are likely at their lowest levels. In this study, we determined the effect of temperature and nutrient levels on the development rates and male and female adult size of 2 Ae. albopictus populations: …

Development Of A Self-Powered Weigh-In-Motion System, Athanassios Papagiannakis, Athanassios Papagiannakis, Samer Dessouky, Sara Ahmed, Reza Khalili, Gopal Vishwakarma

Data

This report describes the development of a novel weigh-in-motion (WIM) system that utilizes piezoelectric elements for sensing load and powering an ultra-low power microcontroller unit (MCU) that serves as its data acquisition system. A system of 4 piezoelectric (PZT) stacks serves as the energy harvester, while load sensing is done via a set of 4 PZT elements connected in parallel. Two alternative MCUs were considered, with various data handling capabilities and power consumption requirements. These MCUs have very short “wake-up” times allowing vehicle sensing without the need for inductive loops commonly used in conventional WIM systems. Special electric circuits were …