Digital Commons Network^™

Deriving Statistical Inference From The Application Of Artificial Neural Networks To Clinical Metabolomics Data, Kevin M. Mendez

Theses: Doctorates and Masters

Metabolomics data are complex with a high degree of multicollinearity. As such, multivariate linear projection methods, such as partial least squares discriminant analysis (PLS-DA) have become standard. Non-linear projections methods, typified by Artificial Neural Networks (ANNs) may be more appropriate to model potential nonlinear latent covariance; however, they are not widely used due to difficulty in deriving statistical inference, and thus biological interpretation. Herein, we illustrate the utility of ANNs for clinical metabolomics using publicly available data sets and develop an open framework for deriving and visualising statistical inference from ANNs equivalent to standard PLS-DA methods.

Development, Assessment And Application Of A Novel Algorithm To Automatically Detect Change Of Direction Movement And Quantify Its Associated Mechanical Load In Elite Australian Football, Aaron Balloch

Theses: Doctorates and Masters

The ability to change direction rapidly and efficiently is critical to team-sport performance, including Australian football (AF), where a player’s capacity to rapidly decelerate, move laterally and re-accelerate is critical when evading opponents, tackling, or reacting to the unpredictable bounce of the ball or movement of another player. The biomechanical loading requirements of change of direction (COD) movement are angle and velocity dependant. Cumulative COD movement can impart high levels of neuromuscular and metabolic fatigue which can adversely affect the efficiency of subsequent movement efforts. Despite widespread use of microtechnology devices (the vast majority containing a global navigation satellite system …

Digital Storytelling As An Astronomy Disciplinary Literacy Enhancement Approach For Adolescent Kyrgyzstani Efl Students, Nadezhda Chubko

Theses: Doctorates and Masters

This research explored the impact of a digital storytelling (DST) video-making intervention in an astronomy course (STEM-A) on EFL students’ STEM-A disciplinary literacy acquisition in English. The research was motivated by the increased significance of English as an international language of STEM instruction and addressed the transition between discourses encountered by students learning STEM in a foreign language.

The study was designed and implemented as a mixed methods four-cycle action research with multiple Case Study, multiple-probe quasi-experimental design. In the first cycle, the researcher transitioned from a teacher of English to speakers of other languages (TESOL) to a teacher of …

Characterising Pd-L1 Expression In Circulating Melanoma And Non-Small Cell Lung Cancer Cells, Isaac Spencer

Theses: Doctorates and Masters

Incidence rates for both melanoma and non-small cell lung cancer (NSCLC) have risen in recent decades. While advanced cases of both diseases have previously demonstrated low survivability, novel therapies such as immune checkpoint inhibitors, have significantly improved the outcome of patients suffering from these cancers. Recent clinical trials have led to the United States Food and Drug Administration (FDA) approving the use of antibodies targeting the PD-1 immune checkpoint for both melanoma and NSCLC. Anti-PD-1 antibodies have been seen to illicit responses in up to 40% of patients, however, particularly for melanoma, there is a lack of biomarkers to select …

Effects Of High-Intensity Position-Specific Drills On Physical And Technical-Skill Performance In Young Soccer Players, Cao Cuong Le

Theses: Doctorates and Masters

Soccer is the most widely played sport in the world, and physical preparation for soccer players has been extensively researched over the years. As the average intensity of a soccer match is close to 80-90% of maximal heart rate (HRmax), it is necessary to train at or above this intensity. Thus, high-intensity interval running and small-sided games are often used to improve aerobic capacity and repeated sprint ability (RSA). However, neither of these approaches consider positional variations in the frequency and type of specific technical skills required in real match situations. Thus, the purpose of this study was to investigate …

Exploring Leadership And Research In Nurse Practitioner Roles Across Australia And Ireland: A Mixed-Methods Study, Mary Ryder

Theses: Doctorates and Masters

Introduction

The Nurse Practitioner role is recognised as the highest level of clinical nursing. Leadership and research are identified as core attributes for Nurse Practitioners in the regulatory frameworks. There is an expectation that as clinical leaders, Nurse Practitioners have the ability to transform healthcare delivery within their specialist area of practice.

Background

The voice of Nurse Practitioners is limited in the current literature related to how they view their leadership contribution to Nursing. There has been some criticism in the evidence to date related to volume, consistency and transferability of Nurse Practitioner research. However, there is a shortage of …

Determining Ground-Level Composition And Concentration Of Particulate Matter Across Regional Areas Using The Himawari-8 Satellite, Miles Sowden

Theses: Doctorates and Masters

Speciated ground-level aerosol concentrations are required to understand and mitigate health impacts from dust storms, wildfires and other aerosol emissions. Globally, surface monitoring is limited due to cost and infrastructure demands. While remote sensing can help estimate respirable (i.e. ground level) concentrations, current observations are restricted by inadequate spatiotemporal resolution, uncertainty in aerosol type, particle size, and vertical profile. One key issue with current remote sensing datasets is that they are derived from reflectances observed by polar orbiting imagers, which means that aerosol is only derived during the daytime, and only once or twice per day.

Sub-hourly, infrared (IR), geostationary …

Adolescents With Autism Spectrum Disorder: Understanding The Influence Of Psychosocial Risk Factors And Mothers’ Help-Seeking Behaviour On The Experience Of Depressive Symptoms, Rachel Gallagher

Theses: Doctorates and Masters

Research has shown that adolescents with Autism Spectrum Disorder (ASD) are at an increased risk for experiencing depressive symptoms (DS) resulting in poor quality of life and further vulnerability for the recurrence of DS in adulthood. Adolescence is a complex developmental period marked by dynamic social contexts that must be effectively navigated for the maturation processes associated with psychological wellbeing. This period is particularly challenging for individuals with ASD due to deficits in social communication skills leading to atypical social functioning. Consequently, psychosocial risk factors of DS for ASD adolescents are likely to be multiple and complex, and prominent risk …

I Walk To See, I Walk To Know: Walking To Wongawol. An Exhibition And I Walk To See, I Walk To Know: Walking To Wongawol. An Exegesis, Cim Sears

Theses: Doctorates and Masters

The context of my embodied project, I Walk to See, I Walk to Know: Walking to Wongawol, is an exploration into 1) the absence of Western Desert Aboriginal narratives via the act of walking as knowing and 2) my recently discovered ancestral connections, which were historically erased by the state. The location of my project is Wongawol Station in the Western Desert, Western Australia, where my Indigenous ancestors lived, and whose lives I draw upon to make connections with the narratives and sensations of the desert landscape. I use the methodology of walking to investigate the interconnectivity between body and …

A Study On Performing The Hungarian Rhapsodies In The Liszt Tradition, Nicholas Mark Williams

Theses: Doctorates and Masters

Franz Liszt’s Hungarian Rhapsodies (1851, 1853) have long been among the most popular collections of piano music. They have also long garnered a reputation for “superficial brilliance and effect” which seems to have influenced the way that famous pianists play the works in public. But would a performer immersed in the Liszt tradition have approached them differently? This dissertation aims to promote a re-evaluation of the Hungarian Rhapsodies from this perspective: considering Liszt’s own ideas on music and performance, the writings and recordings of his pupils, and Liszt’s book Des Bohémiens et de leur musique en Hongrie (1859).

Generation 1.5 Learners: Using An Arts-Informed, Grounded Theory Approach To Understanding How These Students Managed Their Undergraduate Studies In A Perth-Based, Public University In Western Australia Over An Academic Year, Elizabeth Jane Charlotte Serventy

Theses: Doctorates and Masters

The International Organization for Migration’s World Migration Report (2020) estimates the number of migrants worldwide to be approximately 272 million. In an era of demographic scarcity and globalisation-driven uncertainties, asylum seeker, migration, and refugee re-settlement programs are now a worldwide phenomenon. Major English-speaking, immigrant-receiving countries such as Australia, Canada, New Zealand, the United Kingdom, and the United States of America (USA) face associated educational, political, and social repercussions.

Rumbaut and Ima (1988) introduced the term ‘Generation 1.5’ in relation to a distinct cohort of immigrant youth, English as second language (L2) learners studying in San Diego, California in the USA. …

Barriers To Ghanaian Midwives’ Ability To Provide Quality Care: A Glaserian Grounded Theory Study, Yakubu Ismaila

Theses: Doctorates and Masters

The midwifery model of care that promotes the employment of trained and regulated midwives for the provision of maternal and neonatal care has been found to be beneficial, especially in Low and Middle-Income Countries that have high maternal and neonatal mortalities. Midwives in those setting are however, facing a myriad of barriers which negatively affect their ability to provide optimal care. Although Ghana is implementing the midwifery model of care, maternal and neonatal mortality remains high in the country. Little is known from the point of view of midwives, who are the primary providers of maternal and neonatal care, about …

Testing Alphas In Conditional Time-Varying Factor Models With High Dimensional Assets, Shujie Ma, Wei Lan, Liangjun Su, Chih-Ling Tsai

Research Collection School Of Economics

For conditional time-varying factor models with high dimensional assets, this article proposes a high dimensional alpha (HDA) test to assess whether there exist abnormal returns on securities (or portfolios) over the theoretical expected returns. To employ this test effectively, a constant coefficient test is also introduced. It examines the validity of constant alphas and factor loadings. Simulation studies and an empirical example are presented to illustrate the finite sample performance and the usefulness of the proposed tests. Using the HDA test, the empirical example demonstrates that the FF three-factor model (Fama and French, 1993) is better than CAPM (Sharpe, 1964) …

The Legal Recognition Of Electronic Bills Of Lading, Ali Abbas Khayoon Al-Naseri

World Maritime University Ph.D. Dissertations

The increasing use of electronic devices, new means of communication and Internet affects many areas of life, including trade and transportation. One effect is the dematerialization of bills of lading. Paper bills of lading have traditionally performed three main functions in maritime transportation: (1) as a receipt for the goods, (2) as containing or evidencing the contract of carriage of goods and (3) as a document of title. This legal research examines whether electronic bills of lading can legally perform these three functions as functional equivalents to paper bills of lading. It studies the recognition of electronic bills of lading …

2019 Hrs/Ehra/Aphrs/Lahrs Expert Consensus Statement On Catheter Ablation Of Ventricular Arrhythmias, Edmond M Cronin, Phillip Cuculich, Et Al.

2020-Current year OA Pubs

Ventricular arrhythmias are an important cause of morbidity and mortality and come in a variety of forms, from single premature ventricular complexes to sustained ventricular tachycardia and fibrillation. Rapid developments have taken place over the past decade in our understanding of these arrhythmias and in our ability to diagnose and treat them. The field of catheter ablation has progressed with the development of new methods and tools, and with the publication of large clinical trials. Therefore, global cardiac electrophysiology professional societies undertook to outline recommendations and best practices for these procedures in a document that will update and replace the …

Mapping Of Diabetes Susceptibility Loci In A Domestic Cat Breed With An Unusually High Incidence Of Diabetes Mellitus, Lois Balmer, Caroline Ann O’Leary, Marilyn Menotti-Raymond, Victor David, Stephen O’Brien, Belinda Penglis, Sher Hendrickson, Mia Reeves-Johnson, Susan Gottlieb, Linda Fleeman, Dianne Vankan, Jacquie Rand, Grant Morahan

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Genetic variants that are associated with susceptibility to type 2 diabetes (T2D) are important for identification of individuals at risk and can provide insights into the molecular basis of disease. Analysis of T2D in domestic animals provides both the opportunity to improve veterinary management and breeding programs as well as to identify novel T2D risk genes. Australian-bred Burmese (ABB) cats have a 4-fold increased incidence of type 2 diabetes (T2D) compared to Burmese cats bred in the United States. This is likely attributable to a genetic founder effect. We investigated this …

In Situ Wettability Investigation Of Aging Of Sandstone Surface In Alkane Via X-Ray Microtomography, Nilesh Kumar Jha, Maxim Lebedev, Stefan Iglauer, Jitendra S. Sangwai, Mohammad Sarmadivaleh

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Wettability of surfaces remains of paramount importance for understanding various natural and artificial colloidal and interfacial phenomena at various length and time scales. One of the problems discussed in this work is the wettability alteration of a three-phase system comprising high salinity brine as the aqueous phase, Doddington sandstone as porous rock, and decane as the nonaqueous phase liquid. The study utilizes the technique of in situ contact angle measurements of the several 2D projections of the identified 3D oil phase droplets from the 3D images of the saturated sandstone miniature …

A Preliminary Investigation Of Maintenance Contributions To Commercial Air Transport Accidents, Fatima Najeeb Khan, Ayiei Ayiei, John Murray, Glenn Baxter, Graham Wild

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Aircraft maintenance includes all the tasks needed to ensure an aircraft’s continuing airworthiness. Accidents that result from these maintenance activities can be used to assess safety. This research seeks to undertake a preliminary investigation of accidents that have maintenance contributions. An exploratory design was utilized, which commenced with a content analysis of the accidents with maintenance contributions (n = 35) in the official ICAO accident data set (N = 1277), followed by a quantitative ex-post facto study. Results showed that maintenance contributions are involved in 2.8 ± 0.9% of ICAO official …

Broad Spectrum Epidemiological Contribution Of Cannabis And Other Substances To The Teratological Profile Of Northern New South Wales: Geospatial And Causal Inference Analysis, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2014 to 2021

© 2020, The Author(s). Background: Whilst cannabis commercialization is occurring rapidly guided by highly individualistic public narratives, evidence that all congenital anomalies (CA) increase alongside cannabis use in Canada, a link with 21 CA’s in Hawaii, and rising CA’s in Colorado indicate that transgenerational effects can be significant and impact public health. It was therefore important to study Northern New South Wales (NNSW) where cannabis use is high. Methods: Design: Cohort. 2008–2015. Setting: NNSW and Queensland (QLD), Australia. Participants. Whole populations. Exposures. Tobacco, alcohol, cannabis. Source: National Drug Strategy Household Surveys 2010, 2013. Main Outcomes. CA Rates. NNSW-QLD comparisons. Geospatial …

Reply To Lipworth Et Al., Angela M. Moran, Sanjay Ramakrishnan, Catherine A. Borg, Clare M. Connolly, Simon Couillard, Christine M. Mwasuku, Ian D. Pavord, Timothy S.C. Hinks, Lauri Lehtimӓki

Research outputs 2014 to 2021

We thank Dr. Lipworth and colleagues for their interest in our work published recently in the Journal (1). They rightly point out that the biology of asthma attacks is more complex than blood eosinophils alone and that corticosteroids have a wide range of other potentially relevant antiinflammatory effects. However, local treatment with inhaled corticosteroids (ICS) is usually the mainstay of patients with frequent eosinophilic exacerbations, and therefore in the great majority of patients, the key question is what oral corticosteroids (OCS) add to ICS in an acute attack (2) and whether this effect is seen with benralizumab. We suggest that …

Quantifiable Isovist And Graph-Based Measures For Automatic Evaluation Of Different Area Types In Virtual Terrain Generation, Andrew Pech, Chiou Peng Lam, Martin Masek

Research outputs 2014 to 2021

© 2013 IEEE. This article describes a set of proposed measures for characterizing areas within a virtual terrain in terms of their attributes and their relationships with other areas for incorporating game designers' intent in gameplay requirement-based terrain generation. Examples of such gameplay elements include vantage point, strongholds, chokepoints and hidden areas. Our measures are constructed on characteristics of an isovist, that is, the volume of visible space at a local area and the connectivity of areas within the terrain. The calculation of these measures is detailed, in particular we introduce two new ways to accurately and efficiently calculate the …

Contemporary Epidemiology Of Rising Atrial Septal Defect Trends Across Usa 1991–2016: A Combined Ecological Geospatiotemporal And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2014 to 2021

© 2020, The Author(s). Background: Cardiovascular anomalies are the largest group of congenital anomalies and the major cause of death in young children, with various data linking rising atrial septal defect incidence (ASDI) with prenatal cannabis exposure. Objectives / Hypotheses. Is cannabis associated with ASDI in USA? Is this relationship causal? Methods: Geospatiotemporal cohort study, 1991–2016. Census populations of adults, babies, congenital anomalies, income and ethnicity. Drug exposure data on cigarettes, alcohol abuse, past month cannabis use, analgesia abuse and cocaine taken from National Survey of Drug Use and Health (78.9% response rate). Cannabinoid concentrations from Drug Enforcement Agency. Inverse …

Correction To: Cooperative Co‑Evolution For Feature Selection In Big Data With Random Feature Grouping (Journal Of Big Data, (2020), 7, 1, (107), 10.1186/S40537-020-00381-Y), A. N.M.Bazlur Rashid, Mohiuddin Ahmed, Leslie F. Sikos, Paul Haskell‑Dowland

Research outputs 2014 to 2021

© 2020, The Author(s). Following publication of the original article [1], the author reported that the 2nd author affiliation was incorrect. It should only be “School of Science, Edith Cowan University, Joondalup, WA, Australia”. The affiliation is presented correctly in this correction article. The original article [1] has been corrected.

Brainwave Nets: Are Sparse Dynamic Models Susceptible To Brain Manipulation Experimentation?, Diego C. Nascimento, Marco A. Pinto-Orellana, Joao P. Leite, Dylan J. Edwards, Francisco Louzada, Taiza E.G. Santos

Research outputs 2014 to 2021

© Copyright © 2020 Nascimento, Pinto-Orellana, Leite, Edwards, Louzada and Santos. Sparse time series models have shown promise in estimating contemporaneous and ongoing brain connectivity. This paper was motivated by a neuroscience experiment using EEG signals as the outcome of our established interventional protocol, a new method in neurorehabilitation toward developing a treatment for visual verticality disorder in post-stroke patients. To analyze the [complex outcome measure (EEG)] that reflects neural-network functioning and processing in more specific ways regarding traditional analyses, we make a comparison among sparse time series models (classic VAR, GLASSO, TSCGM, and TSCGM-modified with non-linear and iterative optimizations) …

A Sample Weight And Adaboost Cnn-Based Coarse To Fine Classification Of Fruit And Vegetables At A Supermarket Self-Checkout, Khurram Hameed, Douglas Chai, Alexander Rassau

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. The physical features of fruit and vegetables make the task of vision-based classification of fruit and vegetables challenging. The classification of fruit and vegetables at a supermarket self-checkout poses even more challenges due to variable lighting conditions and human factors arising from customer interactions with the system along with the challenges associated with the colour, texture, shape, and size of a fruit or vegetable. Considering this complex application, we have proposed a progressive coarse to fine classification technique to classify fruit and vegetables at supermarket checkouts. The image and weight of …

Australian Consumers Are Willing To Pay For The Health Star Rating Front-Of-Pack Nutrition Label, Sheri L. Cooper, Lucy M. Butcher, Simone D. Scagnelli, Johnny Lo, Maria M. Ryan, Amanda Devine, Therese A. O’Sullivan

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. The Australia and New Zealand Ministerial Forum on Food Regulation has supported the recommendations set out in the 2019 Health Star Rating System Five Year Review Report. Specifically, the forum supported, in principle, Recommendation 9, to mandate the Health Star Rating if clear uptake targets were not achieved while the system is voluntary. Given that mandatory labelling is being considered, it is important to investigate how much consumers value the Health Star Rating in order to understand potential consumer uptake and inform industry. The aim of this study was to assess …

Self-Supervised Learning To Detect Key Frames In Videos, Xiang Yan, Syed Zulqarnain Gilani, Mingtao Feng, Liang Zhang, Hanlin Qin, Ajmal Mian

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Detecting key frames in videos is a common problem in many applications such as video classification, action recognition and video summarization. These tasks can be performed more efficiently using only a handful of key frames rather than the full video. Existing key frame detection approaches are mostly designed for supervised learning and require manual labelling of key frames in a large corpus of training data to train the models. Labelling requires human annotators from different backgrounds to annotate key frames in videos which is not only expensive and time consuming but …

Aesthetic-Ethical-Political Movements In Professional Learning: Encounters With Feminist New Materialisms And Reggio Emilia In Early Childhood Research, Stefania Giamminuti, Jane Merewether, Mindy Blaise

Research outputs 2014 to 2021

© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Professional learning is considered essential for early childhood teachers, and is frequently associated with childhood outcomes and dominant constructs of quality which perpetuate neoliberal ideals and position early childhood teachers within a framework of rationality, privileging discourses of masculinity and power. By engaging with feminist new materialist perspectives, with the concept of ‘movement’, and with the theory-practice of the educational project of the city of Reggio Emilia, Italy, this paper extends understandings of professional learning to include nonhuman others as worthy interlocutors, and puts forth …

Predictors Of Hand Hygiene Behaviours Among Primary And Secondary School Children In A Rural District Setting In Zimbabwe: A Cross-Sectional Epidemiologic Study, France Ncube, Artwell Kanda, Maude Chahwanda, Margaret Macherera, Bigboy Ngwenya

Research outputs 2014 to 2021

© 2020, IWA Publishing. All rights reserved. Hand hygiene is one of the most effective and efficient ways of controlling faecal–oral diseases. However, little is known about the predictors of hand hygiene behaviours among school children. A predesigned checklist guide was used to observe hygiene behaviours of 460 pupils from four rural schools in Shamva South district, Zimbabwe. A pretested questionnaire was administered to obtain demographic data of the observed school children. Membership of a Water, Sanitation and Hygiene (WASH) club, age, gender and the level of education were associated with hand hygiene practices (p < 0.05). The findings indicated that investing in hand hygiene behaviour change processes among school children using the promotion, formation, resuscitation and empowerment of WASH clubs in schools is important in disease prevention among communities in developing countries.

Tripping Over The Other: Could Psychedelics Increase Empathy?, Emily Blatchford, Stephen Bright, Liam Engel

Research outputs 2014 to 2021

There is increasing evidence that psychedelic-assisted psychotherapy is effective for a range of psy-chological conditions. There are likely numerous mechanisms of action that contribute to these clinicaleffects. One such mechanism of action might involve psychedelics increasing levels of empathicfunctioning. This paper synthesises research concerning the relationship between psychedelics andempathy, emphasising neuroscientific and clinical contexts. We conclude that neuropsychological andclinical evidence imply psychedelics could lead to increased empathic functioning. The effects of psy-chedelics on the 5-HT system, default mode network, neural connectivity and ego dissolution areimplicated in these changes. Changes in empathic functioning also likely relate to increases in thepersonality trait …